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Activity of monomeric, dimeric, and trimeric flavonoids on NO production, TNF-alpha secretion, and NF-kappaB-dependent gene expression in RAW 264.7 macrophages. | Flavonoids are potent antioxidants and have been associated with lowering the risk of cardiovascular diseases. In this study, the effect of flavonoids (monomers, dimers and a trimer) as well as French maritime pine bark extract, Pycnogenol, on NO production, tumor necrosis factor-alpha (TNF-alpha) secretion and nuclear... | ['Animals', 'Biopolymers', 'Cell Line', 'Flavonoids', 'Gene Expression Regulation', 'Interferon-gamma', 'Macrophages', 'Mice', 'NF-kappa B', 'Nitric Oxide', 'Tumor Necrosis Factor-alpha'] | 10,631,311 | [['B01.050'], ['D05.750.078', 'D25.720.099', 'J01.637.051.720.099'], ['A11.251.210'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G05.308'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Molecular cloning and expression of a Bacillus subtilis beta-glucanase gene in Escherichia coli. | A Bacillus subtilis gene coding for an endo-beta-1,3-1,4-glucanase has been transferred to Escherichia coli by molecular cloning using bacteriophage lambda and plasmid vectors. The gene is contained within a 1.6-kb EcoRI-PvuI DNA fragment and directs the synthesis in E. coli of a beta-glucanase which specifically degra... | ['Bacillus subtilis', 'Bacteriophage lambda', 'Chromosome Mapping', 'Cloning, Molecular', 'DNA Restriction Enzymes', 'Escherichia coli', 'Genes', 'Genes, Bacterial', 'Genetic Techniques', 'Glycoside Hydrolases', 'Plasmids'] | 6,311,687 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['E05.393.183'], ['E05.393.220'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.3... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Teaching target-oriented and diversity-oriented organic synthesis at Harvard University. | Diversity-oriented synthesis presents many formidable challenges to the practitioners of synthetic organic chemistry. Those challenges include the effective teaching of this new and evolving discipline to ensure that students are well positioned to begin exploring its full potential. Fortunately, the teaching of synthe... | ['Alkylation', 'Chemistry, Organic', 'Curriculum', 'Drug Design', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Organic Chemicals', 'Teaching', 'Universities'] | 12,031,659 | [['G02.111.035', 'G02.607.094', 'G03.059'], ['H01.181.404'], ['I02.158'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02'], ['I02.903'], ['I02.783.830', 'J03.832.830']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
A colourimetric, microplate assay for the leucotoxin of Pasteurella haemolytica. | Culture supernates of Pasteurella haemolytica, which contain leucotoxin, inhibited the reduction of nitroblue tetrazolium (NBT) by bovine and ovine but not rabbit leucocytes in response to phorbol 12-myristate 13-acetate (PMA). Culture supernates of P. multocida, which contain no leucotoxin, had no inhibitory effect on... | ['Animals', 'Bacterial Toxins', 'Cattle', 'Cells, Cultured', 'Colorimetry', 'Cytotoxins', 'Exotoxins', 'Leukocytes', 'Nitroblue Tetrazolium', 'Oxidation-Reduction', 'Pasteurella', 'Sheep', 'Tetradecanoylphorbol Acetate'] | 2,363,244 | [['B01.050'], ['D23.946.123'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['E05.196.922.250'], ['D27.888.569.213'], ['D23.946.350'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['D03.383.129.617.700.500'], ['G02.700', 'G03.295.531'], ['B03.440.450.600.600', 'B03.660.250.550.590'], ['B01.050.150.900.64... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antileishmanial and antifungal activity of plants used in traditional medicine in Brazil. | The antileishmanial and antifungal activity of 24 methanol extracts from 20 plants, all of them used in the Brazilian traditional medicine for the treatment of several infectious and inflammatory disorders, were evaluated against promastigotes forms of two species of Leishmania (L. amazonensis and L. chagasi) and two y... | ['Anacardiaceae', 'Animals', 'Antifungal Agents', 'Antiprotozoal Agents', 'Bixaceae', 'Brazil', 'Cajanus', 'Candida albicans', 'Cryptococcus neoformans', 'Drug Evaluation, Preclinical', 'Inhibitory Concentration 50', 'Leishmania', 'Medicine, Traditional', 'Microbial Sensitivity Tests', 'Ocimum', 'Piper', 'Plant Extract... | 17,234,373 | [['B01.650.940.800.575.912.250.044'], ['B01.050'], ['D27.505.954.122.136'], ['D27.505.954.122.250.100'], ['B01.650.940.800.575.912.250.146'], ['Z01.107.757.176'], ['B01.650.940.800.575.912.250.401.094'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['B01.300.381.258.366', 'B01.300.930.316.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Influence of human T-lymphotropic virus type 1 coinfection on the development of hepatocellular carcinoma in patients with hepatitis C virus infection. | BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1) may worsen the clinical course of hepatitis C virus (HCV) infection. The aim of this study was to investigate whether HTLV-1 coinfection influences the clinical characteristics of patients with HCV infection.METHODS: This retrospective study included 523 consecutiv... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Hepatocellular', 'Coinfection', 'Female', 'Follow-Up Studies', 'HTLV-I Antibodies', 'HTLV-I Infections', 'Hepatitis C, Chronic', 'Human T-lymphotropic virus 1', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Retrospective Studies', 'Risk Factors',... | 24,463,696 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C01.218'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D12.776.124.486.485.114.254.150.500', 'D12.776.124.790.651.114.254.150.500', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evidence for recombination in natural populations of dengue virus type 1 based on the analysis of complete genome sequences. | Recombination events are known to occur in non-segmented RNA viruses like polioviruses or alphaviruses. Analysis of the subgenomic sequences of dengue virus type 1 (DENV-1) structural genes has recently allowed the identification of possible recombination breakpoints. Because DENV is a major human pathogen, this discov... | ['Base Sequence', 'Cambodia', "Cote d'Ivoire", 'DNA, Complementary', 'Dengue Virus', 'Evolution, Molecular', 'Genetic Linkage', 'Genome, Viral', 'Humans', 'Male', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Viral', 'Recombination, Genetic', 'Sequence Alignment', 'Singapore', 'Viral Vaccines'] | 11,369,871 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.145.182'], ['Z01.058.290.190.272'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B04.820.578.344.350.270'], ['G05.045.250', 'G16.075.250'], ['G05.348'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.11... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Cord blood leucocyte expression of functionally significant molecules involved in the regulation of cellular immunity. | The cellular immune system of the newborn infant is immature and hypo-responsive when compared with adults. The extent to which immaturity of the leucocyte function underlies hyporesponsiveness in the newborn is incompletely understood. In this study flow cytometric techniques were applied to investigate the concurrent... | ['Adult', 'Antigens, CD', 'Cells, Cultured', 'Disease Susceptibility', 'Fetal Blood', 'Flow Cytometry', 'Genes, MHC Class II', 'HLA-DR Antigens', 'Humans', 'Immune System', 'Immunity, Cellular', 'Infant, Newborn', 'Interferon-gamma', 'Interleukin-2', 'Interleukin-6', 'Killer Cells, Natural', 'Leukocytes', 'Monocytes', ... | 11,169,209 | [['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251'], ['C23.550.291.687', 'G07.100.250'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.24... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Mycobacterium leprae-specific human T cell epitope cross-reactive with an HLA-DR2 peptide. | Mycobacterium leprae induces T cell reactivity and protective immunity in the majority of exposed individuals, but the minority that develop leprosy exhibit various types of immunopathology. Thus, the definition of epitopes on M. leprae antigens that are recognized by T cells from different individuals might result in ... | ['Amino Acid Sequence', 'Antibodies, Monoclonal', 'Antigens, Bacterial', 'Epitopes', 'HLA-DR Antigens', 'HLA-DR2 Antigen', 'Leprosy', 'Molecular Sequence Data', 'Mycobacterium leprae', 'Peptides', 'T-Lymphocytes', 'T-Lymphocytes, Helper-Inducer'] | 2,459,778 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.161'], ['D23.050.550'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050.301.500.400.400.440', 'D23.050.301.500.450.400.440', 'D23.050.705.552.410.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Diagnostic Accuracy of MR Mammography in Diagnosing Malignant Breast Lesions Taking Histopathology as Gold Standard. | OBJECTIVE: To find out the diagnostic accuracy of MR Mammography in diagnosing malignant breast lesions taking histopathology as gold standard.STUDY DESIGN: Cross-sectional survey.PLACE AND DURATION OF STUDY: Department of Radiology in collaboration with Department of Pathology, Sir Ganga Ram Hospital, Lahore, from Apr... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biopsy', 'Breast', 'Breast Neoplasms', 'Contrast Media', 'Cross-Sectional Studies', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Mammography', 'Middle Aged', 'Pakistan', 'Sensitivity and Specificity'] | 30,630,562 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['D27.505.259.500', 'D27.720.259'], ['E05.318.372.500.875', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of tolmetin sodium dihydrate on normal and postsurgical peritoneal cell function. | Recent studies utilizing intraperitoneal (i.p.) administration of NSAIDs to rabbits after surgical injury to the parietal peritoneum demonstrated macrophage involvement. NSAIDs are known to inhibit the metabolism of arachidonic acid to prostaglandins, which in turn modulate a variety of macrophage functions. Studies pr... | ['Animals', 'Cytotoxicity, Immunologic', 'Female', 'Injections, Intraperitoneal', 'Peritoneal Cavity', 'Peritoneum', 'Phagocytosis', 'Pyrroles', 'Rats', 'Superoxides', 'Time Factors', 'Tolmetin'] | 2,836,323 | [['B01.050'], ['G12.287'], ['E02.319.267.530.490'], ['A01.923.047.025.600.678'], ['A01.923.047.025.600', 'A10.615.789.596'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['D03.383.129.578'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.248.497.158.685.750.850', 'D01.339.431.374.850', 'D01.650.550... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Career options for the dental graduate: report of a conference. | The unexpectedly high attendance (over five hundred) at the conference and the large number of individuals who had to be turned away provide proof that there is considerable interest in diverse dental careers. Interest is high not only among students and recent graduates: there were members of classes ranging from 1940... | ['Career Choice', 'Choice Behavior', 'Dentistry', 'Female', 'Humans', 'Male', 'Professional Practice', 'Students, Dental'] | 6,953,134 | [['F02.463.785.373.346.400'], ['F02.463.785.373.346'], ['E06', 'H02.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.758'], ['M01.848.769.519']] | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A new technique for the treatment of guilt. | A behavioural technique is described suitable for the treatment of patients with high levels of guilt who attempt to relieve their depression by risk-taking activities which reflect their individual wishes and fears, or who suffer anxiety due to unacceptable past behaviour. It is recommended as an alternative brief met... | ['Adult', 'Behavior Therapy', 'Female', 'Guilt', 'Humans', 'Injections, Intravenous', 'Male', 'Methohexital', 'Sexual Behavior'] | 871,573 | [['M01.060.116'], ['F04.754.137'], ['F01.470.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D03.383.742.698.253.488'], ['F01.145.802']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
CEA immunohistochemical localization is correlated with growth and metastasis of human gallbladder carcinoma. | Carcinoembryonic antigen (CEA) is a good marker of colorectal cancer. Recent studies have demonstrated that CEA may function as a metastatic potentiator by different pathways; i.e., modulation of immune responses, facilitation of intercellular adhesion and cellular migration. However, expression patterns of CEA have no... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoembryonic Antigen', 'Female', 'Gallbladder Neoplasms', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Middle Aged', 'Neoplasm Metastasis'] | 10,601,548 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.130.564.401', 'C06.301.120.401'], ['B01.050.150.900.649.313.988.40... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Universality analysis of the existence of substantia nigra "swallow tail" appearance of non-Parkinson patients in 3T SWI. | OBJECTIVE: To use the 3.0T susceptibility-weighted imaging (SWI) for universality analysis of the "swallow tail" appearance in the substantia nigra of non-Parkinson disease and discuss its lack of the value of imaging diagnosis of Parkinson disease (PD).PATIENTS AND METHODS: Take 3.0TMR SWI in 60 PD patients (Group PD)... | ['Aged', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Parkinson Disease', 'Sensitivity and Specificity', 'Substantia Nigra'] | 27,097,951 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Older Russian emigr?s and medical care. | Although emigration from the former Soviet Union is dramatically increasing nationwide, little information has been reported on the medical problems of these emigr?s. For older emigr?s in particular, the medical realities of aging, in combination with cultural expectations, make the United States' medical system an are... | ['Aged', 'Aging', 'Attitude to Health', 'Cohort Studies', 'Cross-Cultural Comparison', 'Culture', 'Delivery of Health Care', 'Emigration and Immigration', 'Ethnic Groups', 'Female', 'Humans', 'Interviews as Topic', 'Jews', 'Male', 'Ukraine', 'United States'] | 1,413,780 | [['M01.060.116.100'], ['G07.345.124'], ['F01.100.150', 'N05.300.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['I01.076.201.450', 'I01.880.853.100'], ['N04.590.374', 'N05.300'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.85... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Recruitment of extravascular fluid by hyperoncotic albumin. | BACKGROUND: Although hyperoncotic albumin may be used to recruit oedema, its effectiveness remains unclear. Therefore, this issue was studied during infusion experiments in healthy volunteers.METHOD: Fifteen healthy volunteers (mean age 31 years) received an infusion of 3 mL/kg of 20% albumin over 30 minutes. Their uri... | ['Adult', 'Albumins', 'Albuminuria', 'Extracellular Fluid', 'Female', 'Fluid Therapy', 'Healthy Volunteers', 'Hematocrit', 'Hemoglobins', 'Humans', 'Infusions, Intravenous', 'Intracellular Fluid', 'Male', 'Middle Aged', 'Osmotic Pressure', 'Plasma Substitutes', 'Plasma Volume', 'Sodium', 'Young Adult'] | 29,845,612 | [['M01.060.116'], ['D12.776.034'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['A11.284.295.260', 'A12.207.270'], ['E02.319.360'], ['M01.774.500', 'M01.955.236'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bystander activation of irrelevant CD4+ T cells following antigen-specific vaccination occurs in the presence and absence of adjuvant. | Autoimmune and other chronic inflammatory diseases (AID) are prevalent diseases which can severely impact the quality of life of those that suffer from the disease. In most cases, the etiology of these conditions have remained unclear. Immune responses that take place e.g. during natural infection or after vaccination ... | ['Adjuvants, Immunologic', 'Animals', 'Antigens', 'Autoimmune Diseases', 'CD4-Positive T-Lymphocytes', 'Chronic Disease', "Freund's Adjuvant", 'Humans', 'Inflammation', 'Lymphocyte Activation', 'Male', 'Mice, Inbred BALB C', 'Mice, Transgenic', 'Proteoglycans', 'Vaccination', 'Vaccines'] | 28,489,886 | [['D27.505.696.477.067'], ['B01.050'], ['D23.050'], ['C20.111'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['C23.550.291.500'], ['D20.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ochratoxin A in conventional and organic cereal derivatives: a survey of the Italian market, 2001-02. | Ochratoxin A is a mycotoxin produced mainly by Penicillium verrucosum and Aspergillus ochraceus. Although typically considered a cereal contaminant, it has also been detected in dried fruit, nuts, meat and derivatives. To estimate the quantity of ochratoxin A that might be ingested by Italian consumers from these foods... | ['Carcinogens', 'Chromatography, High Pressure Liquid', 'Edible Grain', 'Flour', 'Food Analysis', 'Food Contamination', 'Food, Organic', 'Humans', 'Infant', 'Infant Food', 'Italy', 'Ochratoxins'] | 15,204,537 | [['D27.888.569.100'], ['E05.196.181.400.300'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['G07.203.300.484', 'J02.500.484'], ['E05.362', 'J01.576.423.850.100'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Agreement and clinical utility of 2 techniques for measuring cardiac output in patients with low cardiac output. | BACKGROUND: The reliability of cardiac output obtained with the bolus technique is a problem.OBJECTIVES: To compare measurements of cardiac output measured with bolus and continuous techniques in patients with low cardiac output and to determine if measurements obtained with the continuous technique increased the numbe... | ['Cardiac Output', 'Cardiac Output, Low', 'Catheterization, Swan-Ganz', 'Critical Care', 'Decision Making', 'Female', 'Humans', 'Likelihood Functions', 'Male', 'Middle Aged', 'Poisson Distribution', 'Regression Analysis', 'Reproducibility of Results', 'Thermodilution'] | 9,987,544 | [['E01.370.370.380.150', 'G09.330.380.124'], ['C14.280.148', 'C23.888.192'], ['E01.370.370.380.140.210', 'E02.148.224.165', 'E02.148.442.165', 'E04.100.814.529.937.165', 'E04.502.382.937.165', 'E05.157.250.165', 'E05.157.375.165'], ['E02.760.190', 'N02.421.585.190'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hopf bifurcation stability in Hopfield neural networks. | In this paper we consider a simple discrete Hopfield neural network model and analyze local stability using the associated characteristic model. In order to study the dynamic behavior of the quasi-periodic orbit, the Hopf bifurcation must be determined. For the case of two neurons, we find one necessary condition that ... | ['Algorithms', 'Neural Networks, Computer', 'Systems Theory'] | 23,037,776 | [['G17.035', 'L01.224.050'], ['G17.485', 'L01.224.050.375.605'], ['H01.770.808']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Antiproliferative and antimitotic effect, S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells. | Rhodiola rosea is a medicinal plant having stimulating and adaptogenic properties, and some reports also indicate its anticancer and antimutagenic effect. However, the mechanism of its anticancer effect is unknown as there have been no cytological studies regarding cytostatics, cell cycle, induction of apoptosis or the... | ['Antimitotic Agents', 'Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Chromatography, High Pressure Liquid', 'Dose-Response Relationship, Drug', 'HL-60 Cells', 'Humans', 'Mitotic Index', 'Necrosis', 'Plant Extracts', 'Rhodiola', 'S Phase'] | 16,169,692 | [['D27.505.519.593.249', 'D27.505.954.248.147'], ['D27.505.954.248.179'], ['G04.146.954.035'], ['E05.196.181.400.300'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.500', 'E05.200.500... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Edge transfer lithography using alkanethiol inks. | Edge lithographic patterning techniques are based on the utilization of the edges of micrometer-sized template features for the reproduction of submicrometer structures. Edge transfer lithography (ETL) permits local surface modification in a single step by depositing self-assembled monolayers onto a metal substrate sel... | ['Alkanes', 'Gold', 'Ink', 'Materials Testing', 'Nanostructures', 'Nanotechnology', 'Particle Size', 'Printing', 'Sulfhydryl Compounds', 'Surface Properties'] | 16,771,586 | [['D02.455.326.146'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['J01.637.500'], ['E05.570'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['G02.712'], ['L01.737.787'], ['D02.886.489'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[Malnutrition screening in hospitalized children: influence of the hospital unit on its management]. | OBJECTIVES: The aims of this study were to assess the prevalence of malnutrition in a pediatric population hospitalized in a French regional hospital and to evaluate the influence of type of hospital unit (pediatric or not) in the screening and the management of malnutrition.PATIENTS AND METHODS: This one-day cross-sec... | ['Adolescent', 'Body Height', 'Body Mass Index', 'Body Weight', 'Child', 'Child, Hospitalized', 'Child, Preschool', 'Cross-Sectional Studies', 'France', 'Humans', 'Infant', 'Malnutrition', 'Mass Screening', 'Nutrition Assessment', 'Nutrition Surveys', 'Nutritional Status', 'Prevalence'] | 16,051,076 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glove perforation in hand surgery. | A survey of glove perforation in 100 consecutive hand surgery operations was undertaken. A total of 397 pairs of gloves were tested for punctures after the operation. Evidence of perforation was found in 19% of the gloves used, and only in 12 cases did the surgeons actually realize that a perforation had occurred. With... | ['Gloves, Surgical', 'Hand', 'Humans'] | 1,748,747 | [['E07.700.600.400.400', 'E07.858.594.500', 'J01.637.215.600.400.400', 'J01.637.708.560.875.400.400'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of continuous intravenous oxycodone infusion in opioid-na?ve cancer patients with dyspnea. | Aim: Dyspnea is among symptoms that decrease quality of life for terminal cancer patients. There are few reports of the positive effects of oxycodone for the treatment of dyspnea, and no studies have focused on opioid-na?ve patients. This study aimed to determine the efficacy and safety of continuous intravenous oxycod... | ['Aged', 'Aged, 80 and over', 'Analgesics, Opioid', 'Dyspnea', 'Female', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Neoplasms', 'Oxycodone', 'Quality of Life', 'Retrospective Studies', 'Treatment Outcome'] | 29,893,883 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['C08.618.326', 'C23.888.852.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['M01.060.116.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Inflammation resolved by retinoid X receptor-mediated inactivation of leukotriene signaling pathways. | Leukotrienes are implicated in the pathogenesis of diverse, inflammation-driven diseases. Metabolic inactivation of leukotriene signaling is an innate response to resolve inflammation, yet little is known of mechanisms regulating disposition of leukotrienes in peripheral tissues afflicted in common inflammatory disease... | ['Cell Differentiation', 'Cells, Cultured', 'Cytochrome P-450 Enzyme System', 'Epidermal Cells', 'Epidermis', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Inflammation', 'Leukotrienes', 'Retinoid X Receptors', 'Signal Transduction', 'Tretinoin', 'Up-Regulation'] | 17,884,973 | [['G04.152'], ['A11.251'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A11.409'], ['A10.272.497', 'A17.815.250'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D10.251.355.255.100.450', 'D10.251.355.310.166.887', 'D23.469.050.175.450'], ['D12.776.826.701.5... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells. | BACKGROUND: Oxidative stress causes the defects of retinal pigment epithelial (RPE) cells that contribute to age-related macular degeneration (AMD). This study was conducted to determine whether wogonin could prevent H2O2-induced oxidative stress in RPE cells.METHODS: A RPE cell line, ARPE-19, was obtained for the cell... | ['Antioxidants', 'Apoptosis', 'Cell Line', 'Cell Survival', 'Cytoprotection', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Flavanones', 'Humans', 'Hydrogen Peroxide', 'Oxidative Stress', 'Phosphatidylinositol 3-Kinase', 'Phosphorylation', 'Proto-Oncogene Proteins c-akt', 'Retinal Pigment Epithelium', 'Signa... | 25,432,585 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['A11.251.210'], ['G04.346'], ['G07.690.773.500'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Colletotrichum orbiculare MTF4 Is a Key Transcription Factor Downstream of MOR Essential for Plant Signal-Dependent Appressorium Development and Pathogenesis. | The cucumber anthracnose fungus Colletotrichum orbiculare forms a specialized infection structure, called an appressorium. Appressorium differentiation relies on fungal perception of physical and biochemical signals at the plant surface. Our previous report showed that the morphogenesis-related NDR (nuclear Dbf2-relate... | ['Colletotrichum', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Genome, Fungal', 'Mutation', 'Plant Diseases', 'Signal Transduction', 'Transcription Factors'] | 30,398,907 | [['B01.300.381.235'], ['D12.776.354'], ['G05.308.330'], ['G05.360.340.358.365'], ['G05.365.590'], ['G15.610'], ['G02.111.820', 'G04.835'], ['D12.776.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sound localization ability of young children with bilateral cochlear implants. | OBJECTIVE: To evaluate the benefit of bilateral cochlear implantation in young children.STUDY DESIGN: Clinical trial comparing a group of bilaterally implanted children with a group of unilaterally implanted children.SETTING: Tertiary referral center.PATIENTS: Five bilaterally implanted children (mean age at testing, 3... | ['Audiometry', 'Child', 'Child, Preschool', 'Cochlear Implants', 'Deafness', 'Female', 'Functional Laterality', 'Humans', 'Infant', 'Male', 'Meningitis', 'Parents', 'Quality of Life', 'Retrospective Studies', 'Sound Localization', 'Speech Perception', 'Surveys and Questionnaires'] | 17,473,710 | [['E01.370.382.375.060'], ['M01.060.406'], ['M01.060.406.448'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sex differences in genetic and environmental influences on DSM-III-R attention-deficit/hyperactivity disorder. | Approximately 5% of children are affected by attention-deficit/hyperactivity disorder (ADHD), and more boys are affected than girls. This study examined the magnitude of genetic and environmental influences on ADHD and several questions regarding sex differences in its prevalence and liability. The participants were 2,... | ['Adolescent', 'Attention Deficit Disorder with Hyperactivity', 'Australia', 'Bias', 'Child', 'Child, Preschool', 'Comorbidity', 'Conduct Disorder', 'Diseases in Twins', 'Environment', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Models, Genetic', 'Prevalence', 'Regression Analysis', 'Sex Character... | 10,066,990 | [['M01.060.057'], ['F03.625.094.150'], ['Z01.639.100', 'Z01.678.100.373'], ['N05.715.350.150', 'N06.850.490.500'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.625.094.300'], ['C23.550.291.750'], ['G16.500.275', 'N06.230'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
TRAF6-Mediated Inflammatory Cytokines Secretion in LPS-induced Colorectal Cancer Cells Is Regulated by miR-140. | BACKGROUND/AIM: Colorectal cancer (CRC) cells secrete inflammatory cytokines that affect CRC progression. The aim of the present study was to determine if micro-RNA-140(miR-140) regulates inflammatory cytokine secretion induced by lipopolysaccharide (LPS) in colorectal cancer cells by targeting tumor necrosis factor re... | ["3' Untranslated Regions", 'Apoptosis', 'Biomarkers, Tumor', 'Case-Control Studies', 'Cell Proliferation', 'Colorectal Neoplasms', 'Cytokines', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Inflammation Mediators', 'Intracellular Signaling Peptides and Proteins', 'Lipopolysaccharides', 'MicroRNAs', 'Prognosis',... | 31,882,548 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['G04.146.954.035'], ['D23.101.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307', 'C06.301.371... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dietary supplementation with Withania somnifera root powder ameliorates experimentally induced Infectious Bursal Disease in chicken. | Infectious Bursal Disease (IBD) is an economically important, immunosuppressive viral disease of chicken. Withania somnifera, a well-known Indian medicinal plant and functional food, finds extensive ethnomedicinal and ethnoveterinary use in the subcontinent. Root extracts of Withania somnifera have been shown to inhibi... | ['Animals', 'Birnaviridae Infections', 'Chickens', 'Dietary Supplements', 'Female', 'Infectious bursal disease virus', 'Male', 'Plant Extracts', 'Plant Roots', 'Plants, Medicinal', 'Withania'] | 31,705,357 | [['B01.050'], ['C01.925.782.123'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.300.456', 'J02.500.456'], ['B04.820.223.500.060.400'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['B01.650.560'], ['B01.650.940.800.575.912.250.908.500.950']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The misoprostol vaginal insert compared with oral misoprostol for labor induction in term pregnancies: a pair-matched case-control study. | AIM: To compare the efficacy and safety of the misoprostol vaginal insert (MVI) with an off-label use of oral misoprostol (OM).METHODS: Pair-matched case-control study comparing the induction of labor with a retrievable MVI to OM. The primary outcomes were the time from induction to delivery and the cesarean section ra... | ['Administration, Intravaginal', 'Administration, Oral', 'Case-Control Studies', 'Cesarean Section', 'Female', 'Humans', 'Infant, Newborn', 'Labor, Induced', 'Misoprostol', 'Oxytocics', 'Pregnancy', 'Pregnancy Outcome'] | 28,672,758 | [['E02.319.267.120.500'], ['E02.319.267.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.520.252.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E04.520.252.968'], ['D10.251.355.255.550.775.450.500', 'D23.469.050.175.725.775.450.500', 'D23.469.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy of different antibiotics in the treatment of pelvic inflammatory disease. | A total of 40 patients with acute pelvic inflammatory disease (APID) were studied over a period of 7 months; one aim was to evaluate the use of different antibiotics in treatment. The most important findings were: (i) most patients had a polymicrobial aetiology for their APID; (ii) Chlamydia trachomatis and the anaerob... | ['Ampicillin', 'Anti-Bacterial Agents', 'Doxycycline', 'Drug Evaluation', 'Drug Therapy, Combination', 'Female', 'Humans', 'Metronidazole', 'Oxytetracycline', 'Pelvic Inflammatory Disease', 'Random Allocation', 'Tetracycline'] | 3,616,808 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D27.505.954.122.085'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['E05.290.625', 'E05.337.425'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.640.672.500', 'D03.383.129.308.658.500'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Throat disease in the periphery of Europe: the introduction of diphteria antitoxin in Romsdal county]. | Diphteria played a key role in establishing the bacteriological model for explaining infectious disease. This understanding of bacteriological factors spurred research that culminated in the development of diphteria antitoxin, the first effective therapeutic cure for an epidemiological disease. Prior to the introductio... | ['Diphtheria', 'Diphtheria Antitoxin', 'Healthcare Disparities', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Immunologic Factors', 'Medically Underserved Area', 'Norway'] | 24,721,865 | [['C01.150.252.410.040.246.388'], ['D12.776.124.486.485.114.573.601.438', 'D12.776.124.790.651.114.573.601.438', 'D12.776.377.715.548.114.573.601.438', 'D20.215.401.601.388'], ['N04.590.374.380', 'N05.300.493'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Prediction models of donor arrest and graft utilization in liver transplantation from maastricht-3 donors after circulatory death. | Shortage of organs for transplantation has led to the renewed interest in donation after circulatory-determination of death (DCDD). We conducted a retrospective analysis (2001-2009) and a subsequent prospective validation (2010) of liver Maastricht-Category-3-DCDD and donation-after-brain-death (DBD) offers to our prog... | ['Adult', 'Aged', 'Brain Death', 'Child', 'Female', 'Graft Survival', 'Heart Arrest', 'Humans', 'Liver Transplantation', 'Male', 'Middle Aged', 'Models, Statistical', 'Organ Preservation', 'Prognosis', 'Prospective Studies', 'Retrospective Studies', 'Tissue Donors', 'Tissue and Organ Procurement'] | 23,016,623 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.151', 'C10.597.606.358.800.200.100', 'C23.550.260.159'], ['M01.060.406'], ['G12.875.545.340'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of Approaches to Analyzing Continuous Correlated Eye Data When Sample Size Is Small. | PURPOSE: To evaluate the performance of commonly used statistical methods for analyzing continuous correlated eye data when sample size is small.METHODS: We simulated correlated continuous data from two designs: (1) two eyes of a subject in two comparison groups; (2) two eyes of a subject in the same comparison group, ... | ['Computer Simulation', 'Data Interpretation, Statistical', 'Disease Management', 'Eye Diseases', 'Humans', 'Models, Statistical', 'Sample Size'] | 28,891,730 | [['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['N04.590.607'], ['C11'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.370.762', 'E05.581.500.902... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[General practice and family medicine vocational training: the specialty internship doctor's profile, in Portugal]. | AIM: To characterize a vocational training doctor's population that chooses General Practice and Family Medicine as career, in Portugal, trying to identify a profile; to know the proportion of the trainees that choose this specialty as a first-line option, for their professional future; to analyze the relationship betw... | ['Adult', 'Career Choice', 'Cross-Sectional Studies', 'Family Practice', 'Female', 'Humans', 'Male', 'Portugal'] | 20,353,706 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.727']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of alkaline growth pH on the expression of cell envelope proteins in Fusobacterium nucleatum. | Fusobacterium nucleatum is a Gram-negative anaerobic organism that plays a central role in the development of periodontal diseases. The progression of periodontitis is associated with a rise in pH of the gingival sulcus which promotes the growth and expression of virulence factors by periodontopathic bacteria. We have ... | ['Bacterial Outer Membrane Proteins', 'Fusobacterium nucleatum', 'Gene Expression Regulation, Bacterial', 'Gingiva', 'Hydrogen-Ion Concentration', 'Periplasm', 'Proteome', 'Virulence'] | 20,299,401 | [['D12.776.097.120', 'D12.776.543.100'], ['B03.370.250.500', 'B03.440.425.410.420.500'], ['G05.308.300'], ['A14.549.167.646.480'], ['G02.300'], ['A11.284.295.680'], ['D12.776.817'], ['G06.930']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Validation of the GAP score in Korean patients with idiopathic pulmonary fibrosis. | BACKGROUND: No study has determined whether the risk of mortality predicted by the GAP (gender, age, and physiologic variables) model matches the observed mortality from idiopathic pulmonary fibrosis (IPF) in non-Western populations. We evaluated the clinical course of IPF and validated the GAP model in Korean patients... | ['Aged', 'Disease Progression', 'Female', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Models, Statistical', 'Retrospective Studies', 'Risk Assessment'] | 25,211,374 | [['M01.060.116.100'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.765.500'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Maturation-promoting factor governs mitogen-activated protein kinase activation and interphase suppression during meiosis of rat oocytes. | Meiosis is a particular example of a cell cycle, characterized by two successive divisions without an intervening interphase. Resumption of meiosis in oocytes is associated with activation of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK). The activity of MPF declines during the transitio... | ['Animals', 'Cyclic AMP', 'Cyclin B', 'Cyclin B1', 'Enzyme Activation', 'Female', 'Interphase', 'Maturation-Promoting Factor', 'Meiosis', 'Mitogen-Activated Protein Kinases', 'Oncogene Proteins v-mos', 'Oocytes', 'Rats', 'Rats, Wistar'] | 12,606,439 | [['B01.050'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.644.360.262.120', 'D12.776.167.218.120', 'D12.776.476.262.120'], ['D12.644.360.262.120.100', 'D12.776.167.218.120.100', 'D12.776.476.262.120.100'], ['G02.111.263', 'G03.328'], ['G04.144.500'], ['D08.811... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression Patterns and Potential Biological Roles of Dip2a. | Disconnected (disco)-interacting protein 2 homolog A is a member of the DIP2 protein family encoded by Dip2a gene. Dip2a expression pattern has never been systematically studied. Functions of Dip2a in embryonic development and adult are not known. To investigate Dip2a gene expression and function in embryo and adult, a... | ['Animals', 'Embryo, Mammalian', 'Female', 'Gene Expression', 'Gene Expression Regulation', 'Gene Expression Regulation, Developmental', 'Genes, Reporter', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Transgenic', 'Nuclear Proteins', 'Organ Specificity', 'Receptors, Cell Surface', 'beta-Galactosidase'] | 26,605,542 | [['B01.050'], ['A16.254'], ['G05.297'], ['G05.308'], ['G05.308.310'], ['G05.360.340.024.340.435'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Phase II randomized study of daily gefitinib treatment alone or with vinorelbine every 2 weeks in patients with adenocarcinoma of the lung who failed at least 2 regimens of chemotherapy. | BACKGROUND: The objective of this study was to assess the efficacy of adding chronic, intermittent, low-dose vinorelbine to gefitinib treatment for patients who had adenocarcinoma of the lung who failed>or=2 regimens of chemotherapy.METHODS: Patients were randomized into 2 arms: Oral gefitinib 250 mg daily (the G arm) ... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Non-Small-Cell Lung', 'DNA Mutational Analysis', 'Disease-Free Survival', 'Drug Resistance, Neoplasm', 'ErbB Receptors', 'Female', 'Gefitinib', 'Humans', 'In Situ Hybridization, Fluorescence', 'Kaplan-... | 17,351,950 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.393.760.700.300'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of MS-857, a new and potent cardiotonic agent, in isolated mammalian cardiac muscles. | The positive inotropic activity of MS-857, a novel cardiotonic agent, was assessed in isolated atrial and ventricular muscle of several mammalian species. MS-857 (0.1-300 microM) increased the developed tension of the dog, rabbit, monkey, cat, and guinea pig ventricular muscles in a concentration-dependent manner. Howe... | ['1-Methyl-3-isobutylxanthine', 'Animals', 'Carbachol', 'Cardiotonic Agents', 'Cats', 'Cyclic AMP', 'Cyclic GMP', 'Dogs', 'Female', 'Guinea Pigs', 'Heart', 'In Vitro Techniques', 'Isoquinolines', 'Macaca mulatta', 'Male', 'Milrinone', 'Myocardial Contraction', 'Pyridones', 'Rabbits', 'Rats', 'Rats, Inbred Strains', 'Re... | 2,481,195 | [['D03.633.100.759.758.824.751.500'], ['B01.050'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['D27.505.954.411.222', 'D27.720.799.080'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A cadaveric investigation into the links between macroscopic and microscopic osteoarthritic changes at the hip. | Our objective was to investigate the frequency and distribution of osteoarthritic changes at the hip, including the relationship between osteoarthritic lesions on the femoral head surface and histological changes in articular cartilage, in 12 cadavers. Twelve embalmed cadavers (five males and seven females) were dissec... | ['Aged', 'Aged, 80 and over', 'Cadaver', 'Cartilage, Articular', 'Chondrocytes', 'Female', 'Femur Head', 'Humans', 'Male', 'Orthopedics', 'Osteoarthritis, Hip'] | 16,283,648 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.260.224'], ['A02.165.407.150', 'A02.835.583.192'], ['A11.329.171'], ['A02.835.232.043.150.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.494'], ['C05.550.114.606.400', 'C05.799.613.400']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Ampicillin and propylthiouracil pharmacokinetics in intestinal bypass patients followed up to a year after operation. | The pharmacokinetics of ampicillin and prophylthiouracil were studied in 6 and 9 patients, respectively, before and several times up to a year after a shunt operation for extreme obesity. The drugs were given intravenously and orally making it possible to estimate the absolute bioavailability. The bioavailability of pr... | ['Adult', 'Ampicillin', 'Female', 'Humans', 'Ileum', 'Intestinal Absorption', 'Jejunum', 'Kinetics', 'Male', 'Middle Aged', 'Obesity', 'Propylthiouracil', 'Time Factors'] | 6,713,763 | [['M01.060.116'], ['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The impact of single and dual hydrothermal modifications on the molecular structure and physicochemical properties of normal corn starch. | Effect of single and dual hydrothermal modifications with annealing (ANN) and heat-moisture treatment (HMT) on molecular structure and physicochemical properties of corn starch was investigated. Normal corn starch was modified by ANN at 70% moisture at 50 degrees C for 24h and HMT at 30% moisture at 120 degrees C for 2... | ['Amylopectin', 'Amylose', 'Animals', 'Crystallization', 'Enzymes', 'Gelatin', 'Hydrolysis', 'Spectroscopy, Fourier Transform Infrared', 'Starch', 'Sus scrofa', 'Temperature', 'Water', 'X-Ray Diffraction'] | 19,136,026 | [['D09.301.915.194', 'D09.698.365.855.194'], ['D09.301.915.361', 'D09.698.365.855.361'], ['B01.050'], ['E05.196.300', 'G02.171'], ['D08.811'], ['D12.776.860.476'], ['G02.380'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855'], ['B01.050.150.900.649.313.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The MMPI and the MCMI in the evaluation of narcissism in a clinical sample. | Narcissistic and nonnarcissistic groups of psychiatric patients (n = 35 in each group) were formed on the basis of a criterion comprised of clinical judgment and scores on the Narcissistic Personality Inventory and compared on the Minnesota Multiphasic Personality Inventory (MMPI) and the Millon Clinical Multiaxial Inv... | ['Adult', 'Female', 'Humans', 'MMPI', 'Male', 'Mental Disorders', 'Narcissism', 'Personality Assessment', 'Personality Disorders', 'Personality Inventory', 'Psychometrics'] | 8,473,963 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.647.513.607'], ['F03'], ['F02.739.794.582'], ['F04.513'], ['F03.675'], ['F04.711.647.513'], ['F04.711.780']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Polysomnographic outcomes following lingual tonsillectomy for persistent obstructive sleep apnea in down syndrome. | OBJECTIVES/HYPOTHESIS: Lingual tonsil hypertrophy is a common cause of persistent airway obstruction in patients with Down syndrome (DS) following adenotonsillectomy (T&A); however, little is known about the effect of lingual tonsillectomy (LT) on polysomnographic outcomes in these patients. Our objective was to descri... | ['Adenoidectomy', 'Adolescent', 'Child', 'Down Syndrome', 'Female', 'Humans', 'Hypertrophy', 'Male', 'Palatine Tonsil', 'Polysomnography', 'Retrospective Studies', 'Sleep Apnea, Obstructive', 'Tongue', 'Tonsillectomy'] | 27,515,709 | [['E04.580.068'], ['M01.060.057'], ['M01.060.406'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['A04.623.603.925', 'A10.549.580', 'A14.724.603.925', 'A15.382.520.604.580'], ['E01.370.520.625'], ['E05.318.372.500.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of Bax in glutamate-induced nerve cell death. | The role of the Bax gene product was examined in three forms of cortical nerve cell death in primary cultures. These include spontaneous cell death, oxidative glutamate toxicity, in which exogenous glutamate inhibits cystine uptake resulting in toxic oxidative stress, and ionotropic glutamate receptor-mediated excitoto... | ['Animals', 'Apoptosis', 'Cell Death', 'Cell Survival', 'Cells, Cultured', 'Enzyme Inhibitors', 'Glutamic Acid', 'Heterozygote', 'Homozygote', 'Mice', 'Mice, Inbred BALB C', 'Mice, Knockout', 'Neurons', 'Oxidative Stress', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-bcl-2', 'Receptors, Glutamate', 'Receptors,... | 11,146,002 | [['B01.050'], ['G04.146.954.035'], ['G04.146'], ['G04.346'], ['A11.251'], ['D27.505.519.389'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['G05.380.383'], ['G05.380.554'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.33... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A combination of soft-shell turtle powder and essential oil of a unicellular chorophyte prevents bone loss and decreased bone strength in ovariectomized rats. | The effects of soft-shell turtle (Trionyx sinensis) powder (SST) on the proximal tibiae of ovariectomized (OVX) rats were investigated using peripheral quantitative computed tomography (pQCT) and examination of serum biochemical markers. Considering the relationship between the antioxidative property and antiosteoporot... | ['Animals', 'Bone Density', 'Drug Therapy, Combination', 'Eukaryota', 'Female', 'Oils, Volatile', 'Osteoporosis', 'Ovariectomy', 'Powders', 'Rats', 'Rats, Wistar', 'Turtles'] | 15,684,483 | [['B01.050'], ['G11.427.100'], ['E02.319.310'], ['B01'], ['D10.627.675'], ['C05.116.198.579', 'C18.452.104.579'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['D26.255.779'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['B01.050.150.900.833.848']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of Xenopus gastrulation by ErbB signaling. | During Xenopus gastrulation, mesendodermal cells are internalized and display different movements. Head mesoderm migrates along the blastocoel roof, while trunk mesoderm undergoes convergent extension (C&E). Different signals are implicated in these processes. Our previous studies reveal that signals through ErbB recep... | ['Animals', 'Cell Adhesion', 'Cell Movement', 'ErbB Receptors', 'Gastrula', 'Immunohistochemistry', 'In Situ Hybridization', 'In Situ Nick-End Labeling', 'Mesoderm', 'Morphogenesis', 'Oligonucleotides', 'Receptor, ErbB-4', 'Signal Transduction', 'Xenopus'] | 17,134,691 | [['B01.050'], ['G04.022'], ['G04.198', 'G07.568.500.180'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['A16.441'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Distinct cortical areas for names of numbers and body parts independent of language and input modality. | Some models of word comprehension postulate that the processing of words presented in different modalities and languages ultimately converges toward common cerebral systems associated with semantic-level processing and that the localization of these systems may vary with the category of semantic knowledge being accesse... | ['Adult', 'Behavior', 'Brain', 'Cerebral Cortex', 'Female', 'Human Body', 'Humans', 'Language', 'Magnetic Resonance Imaging', 'Male', 'Mathematics', 'Mental Processes', 'Middle Aged', 'Names', 'Parietal Lobe', 'Prefrontal Cortex', 'Reproducibility of Results'] | 10,988,032 | [['M01.060.116'], ['F01.145'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['I01.076.201.450.560', 'K01.093.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['E01.370.350.825.500'], ['H01.548'], ['F02.463'], ['M01.060.116.630'], ['L01.559.598.400.556'], ['A08.186.211.200.885... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Differential effects of monocular deprivation seen in different layers of the lateral geniculate nucleus. | Recent investigations have suggested that the morphological effects of monocular deprivation can be explained by a developmental competitive interaction between the pathways from the two eyes. This study presents evidence in the tree shrew for binocular competition and for an unequal effect of such competition on the d... | ['Animals', 'Eye', 'Functional Laterality', 'Geniculate Bodies', 'Ocular Physiological Phenomena', 'Strepsirhini', 'Tupaiidae'] | 417,098 | [['B01.050'], ['A01.456.505.420', 'A09.371'], ['F02.830.297.425', 'G11.561.225.425'], ['A08.186.211.200.317.826.701.444'], ['G14'], ['B01.050.150.900.649.313.988.700'], ['B01.050.150.900.649.313.996.770']] | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of multiattribute decision models in evaluating triptan treatment options in migraine. | BACKGROUND: The physician treating patients with migraine is now able to choose from among seven triptans-almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan and zolmitriptan. These differ, to greater or lesser degrees, on a range of clinical attributes important for treatment selection.OBJECTI... | ['Clinical Trials as Topic', 'Decision Support Techniques', 'Humans', 'Migraine Disorders', 'Tryptamines'] | 15,761,676 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.546.399.750'], ['D02.092.211.215.801', 'D03.633.100.473.914']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Biotransformations of oxaliplatin in rat blood in vitro. | The partitioning and biotransformations of oxaliplatin [trans-l-1,2-diaminocyclohexaneoxalatoplatinum(II)] were investigated in the blood of Wistar male rats in vitro. [3-H]-Oxaliplatin was incubated with rat blood at 37 degrees C in 5% CO2 and the concentrations of all Pt complexes containing the [3-H]-dach carrier li... | ['Animals', 'Antineoplastic Agents', 'Biotransformation', 'Chromatography, High Pressure Liquid', 'Half-Life', 'Male', 'Organoplatinum Compounds', 'Oxaliplatin', 'Rats', 'Rats, Wistar'] | 10,098,901 | [['B01.050'], ['D27.505.954.248'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.196.181.400.300'], ['G01.910.405'], ['D02.691.788'], ['D02.257.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of alcohol and extract concentration in beer samples using a combined method of near-infrared (NIR) spectroscopy and refractometry. | A new approach of combination of near-infrared (NIR) spectroscopy and refractometry was developed in this work to determine the concentration of alcohol and real extract in various beer samples. A partial least-squares (PLS) regression, as multivariate calibration method, was used to evaluate the correlation between th... | ['Beer', 'Ethanol', 'Refractometry', 'Spectroscopy, Near-Infrared'] | 21,090,679 | [['G07.203.100.100.200', 'G07.203.200.250', 'J02.200.100.200', 'J02.350.250'], ['D02.033.375'], ['E05.196.808', 'H01.671.617.755'], ['E01.370.350.750', 'E05.196.867.851']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Evidence of cross-fertilization in a gonochoric population of the tadpole shrimp Triops numidicus (Crustacea: Branchiopoda: Notostraca). | Cross-fertilization was evident in a gonochoric population of the notostracan Triops numidicus, in which a thick, hard eggshell had been suspected of preventing the sperm from reaching the egg. Most of the eggs from copulated females hatched into larvae, but the eggs from virgin females did not develop. In the larvae, ... | ['Animals', 'DNA', 'Decapoda', 'Female', 'Larva', 'Male', 'Oviposition', 'Ovum', 'Sperm-Ovum Interactions', 'Spermatozoa'] | 17,261,925 | [['B01.050'], ['D13.444.308'], ['B01.050.500.131.365.190'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G08.686.784.480'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['G08.686.784.277.800'], ['A05.360.490.890', 'A11.497.760']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Semantic priming effects in a lexical decision task: comparing third graders and college students in two different stimulus onset asynchronies. | Differences in the semantic priming effect comparing child and adult performance have been found by some studies. However, these differences are not well established, mostly because of the variety of methods used by researchers around the world. One of the main issues concerns the absence of semantic priming effects on... | ['Adolescent', 'Adult', 'Aging', 'Child', 'Cues', 'Decision Making', 'Humans', 'Male', 'Mental Recall', 'Paired-Associate Learning', 'Psycholinguistics', 'Reaction Time', 'Semantics', 'Young Adult'] | 22,059,305 | [['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['M01.060.406'], ['F02.463.425.234'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.425.952.500'], ['F02.694', 'F04.096.586', 'L01.559.598.628'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], [... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Context-dependent impairment of recollection in list-method directed forgetting. | In list-method directed forgetting, people's ability to forget one of the sets of learned material is examined. Research shows that memory for to-be-forgotten items is impaired when assessed by a recall test and by recognition tests reliant on recollective processes. Retrieval inhibition and context-change mechanisms h... | ['Analysis of Variance', 'Association Learning', 'Discrimination, Psychological', 'Female', 'Humans', 'Male', 'Memory', 'Mental Recall', 'Motivation', 'Psychomotor Performance', 'Recognition, Psychology', 'Verbal Learning', 'Young Adult'] | 22,862,302 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.463.425.069.296'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['F01.658', 'F01.752.543.500.750'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.463.425.540.706'], ['F02.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of P2Y(14) protein in platelets and investigation of the role of P2Y(14) in platelet function in comparison with the EP(3) receptor. | mRNA encoding the recently discovered P2Y(14) receptor has been reported in platelets, but the presence of P2Y(14) receptor protein and its functionality have not been studied. If P2Y(14) is expressed along with P2Y(1) and P2Y(12) receptors it may have a role in haemostasis. It was the objective of this study to invest... | ['Adenosine Diphosphate', 'Adenosine Monophosphate', 'Animals', 'Blood Platelets', 'Cell Adhesion Molecules', 'Dinoprostone', 'Humans', 'Immunoblotting', 'Microfilament Proteins', 'Microscopy, Confocal', 'Phosphoproteins', 'Phosphorylation', 'Platelet Aggregation', 'Platelet Count', 'Purinergic P2 Receptor Agonists', '... | 18,690,346 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D10.251.355.255.550.250.200', 'D23.469.050.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolated autosomal dominant type E brachydactyly: exclusion of linkage to candidate regions 2q37 and 20q13. | Type E brachydactyly is a digital malformation which characteristically causes an asymmetrical shortening of one or more metacarpals or metatarsals or both. Although commonly seen as part of a syndrome, it can be inherited as an autosomal dominant characteristic, the gene acting with variable expressivity, but complete... | ['Chromosomes, Human, Pair 2', 'Chromosomes, Human, Pair 20', 'Female', 'Fingers', 'Genes, Dominant', 'Genetic Linkage', 'Humans', 'Male', 'Pedigree', 'Toes'] | 8,933,344 | [['A11.284.187.520.300.235.245', 'G05.360.162.520.300.235.245'], ['A11.284.187.520.300.460.470', 'G05.360.162.520.300.460.470'], ['A01.378.800.667.430'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.673'], ['A01.378.610.250.300.792']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Colour vision can contribute to fast corrections of arm movements. | Can chromatic information be used for the fast on-line control of action? In order to find out we asked subjects to tap a red square as quickly as possible. In half of the trials the red square's position changed as soon as the subject's hand started to move. We examined how quickly subjects could adjust their movement... | ['Acceleration', 'Arm', 'Color Perception', 'Feedback', 'Humans', 'Lighting', 'Movement', 'Photic Stimulation', 'Psychomotor Performance', 'Reaction Time', 'Visual Perception'] | 15,167,975 | [['G01.482.107'], ['A01.378.800.075'], ['F02.463.593.932.217'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.230.150.410'], ['G07.568', 'G11.427.410'], ['E05.723.729'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.9... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The evaluation of therapeutic efficacy of hachimi-jio-gan (traditional Chinese medicine) to rat galactosemic cataract. | Hachimi-jio-gan (Rehmannia Eight Formula, pa-wei-ti-huang-wan or Bawei dihuang wan) is one of traditional Chinese medicines which has been used for treating various senile disease for a few hundred years. This drug was evaluated for its therapeutic efficacy to rat galactosemic cataract from the suppressive rate of vari... | ['Animals', 'Calcium', 'Cataract', 'Drugs, Chinese Herbal', 'Galactosemias', 'Lens, Crystalline', 'Male', 'Potassium', 'Rats', 'Rats, Inbred Strains', 'Sodium', 'Therapeutic Equivalency'] | 3,503,915 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C11.510.245'], ['D20.215.784.500.350', 'D26.335'], ['C10.228.140.163.100.320', 'C16.320.565.189.320', 'C16.320.565.202.355', 'C18.452.132.100.320', 'C18.452.648.189.320', 'C18.452.648.202.355'], ['A09.371.060.500'], ['D01.268.549.550', 'D01.268.557.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of single pulse electrical stimulation (SPES) to guide electrode implantation under general anaesthesia in presurgical assessment of epilepsy. | PURPOSE: Single-pulse electrical stimulation (SPES) during intracranial recordings is part of the epilepsy presurgical evaluation protocol at King's College Hospital (London). Epileptiform responses correlated to the stimulus (delayed responses - DRs) tend to occur in areas of seizure onset, thereby allowing interictal... | ['Adult', 'Brain Mapping', 'Cerebral Cortex', 'Child', 'Electric Stimulation', 'Electrodes, Implanted', 'Electroencephalography', 'Epilepsy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Preoperative Period'] | 23,298,606 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['M01.060.406'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prenatal Contraceptive Counseling by Video. | OBJECTIVE: Effective postpartum contraception can improve interpregnancy intervals. Opportunities exist for counseling and education during prenatal care. Few studies have assessed the use of multimedia as a tool to improve long-acting reversible contraception (LARC) use postpartum. The objective of this study was to e... | ['Adult', 'Birth Intervals', 'Contraception', 'Counseling', 'Delivery of Health Care', 'Family Planning Services', 'Female', 'Humans', 'Long-Acting Reversible Contraception', 'Patient Acceptance of Health Care', 'Postpartum Period', 'Pregnancy', 'Prenatal Care', 'Video Recording', 'Young Adult'] | 30,608,623 | [['M01.060.116'], ['I01.240.361.150', 'N01.224.361.150'], ['E02.875.194'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['N04.590.374', 'N05.300'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.875.194.589'], ['F01.100.150.750.500', 'F01.145.488.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome. | UNLABELLED: Acetaminophen (APAP) overdose is a major cause of acute liver failure (ALF). Numerous studies have shown that APAP hepatotoxicity in mice involves mitochondrial dysfunction, and recent data suggest that this is also the case in humans. We have previously shown that glutamate dehydrogenase (GDH), mitochondri... | ['Acetaminophen', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers', 'Case-Control Studies', 'Chemical and Drug Induced Liver Injury', 'DNA', 'DNA Fragmentation', 'DNA, Mitochondrial', 'Dose-Response Relationship, Drug', 'Female', 'Glutamate Dehydrogenase', 'Humans', 'Male', 'Middle Aged', 'Predictive Va... | 24,923,598 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['D13.444.308'], ['G05.200.230'], ['D13.444.308.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tissue engineering of heart valves: in vitro experiences. | BACKGROUND: Tissue engineering is a new approach, whereby techniques are being developed to transplant autologous cells onto biodegradable scaffolds to ultimately form new functional tissue in vitro and in vivo. Our laboratory has focused on the tissue engineering of heart valves, and we have fabricated a trileaflet he... | ['Animals', 'Biomedical Engineering', 'Bioprosthesis', 'Cells, Cultured', 'Culture Techniques', 'Heart Valve Prosthesis', 'Prosthesis Design', 'Sheep'] | 10,921,698 | [['B01.050'], ['H02.070', 'J01.293.140'], ['E07.695.100'], ['A11.251'], ['E05.481.500'], ['E07.695.310'], ['E05.320.550', 'E07.695.680'], ['B01.050.150.900.649.313.500.380.791']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Natural history of Helicobacter pylori infection in childhood: 12-year follow-up cohort study in a biracial community. | We assessed the pattern of acquisition and loss of Helicobacter pylori infection in a cohort of 212 children from a biracial community with a homogeneous socioeconomic class. The children were followed over 12 years (1973-1974 to 1985-1986) from childhood to young adulthood. H. pylori status was assessed by the presenc... | ['Adult', 'African Continental Ancestry Group', 'Age Factors', 'Child', 'Cohort Studies', 'European Continental Ancestry Group', 'Female', 'Follow-Up Studies', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Prevalence', 'Residence Characteristics', 'Sex Factors'] | 10,064,244 | [['M01.060.116'], ['M01.686.508.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['M01.686.508.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.150.252.400.466'], ['B03.44... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nutrient content of the diet when the fat is reduced. | When the fat content of the typical US diet was reduced from 40 to 44% of total energy (en %) to approximately 25 en % there was a marked improvement in the overall nutrient content of the diet. Cholesterol, saturated fatty acid, and monounsaturated fatty acid intake were decreased and the polyunsaturated fatty acid co... | ['Dietary Carbohydrates', 'Dietary Fats', 'Dietary Fiber', 'Dietary Proteins', 'Energy Intake', 'Energy Metabolism', 'Fatty Acids, Unsaturated', 'Humans', 'Minerals', 'Nutritive Value', 'Vitamins'] | 2,844,078 | [['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.240.340'], ['G03.295'], ['D10.251.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.578'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A cytokinesis-blocked micronucleus study of the radioadaptive response of lymphocytes of individuals occupationally exposed to chronic doses of radiation. | Human lymphocytes pre-exposed to very low doses of ionizing radiation show an adaptive response, which make these cells less sensitive to subsequent higher exposures. To verify the hypothesis that a similar phenomenon can be induced by occupationally (in vivo) received doses of ionizing radiation, the cytogenetic respo... | ['Adult', 'Cells, Cultured', 'DNA Damage', 'DNA Repair', 'Dose-Response Relationship, Radiation', 'Female', 'Gamma Rays', 'Health Personnel', 'Humans', 'Lymphocytes', 'Male', 'Maximum Allowable Concentration', 'Micronucleus Tests', 'Middle Aged', 'Occupational Exposure', 'Radiation Tolerance', 'Radiology', 'Technology,... | 9,800,192 | [['M01.060.116'], ['A11.251'], ['G05.200'], ['G02.111.222', 'G05.219'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A1... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Motor unit activity, force steadiness, and perceived fatigability are correlated with mobility in older adults. | The purpose of our study was to examine the associations between the performance of older adults on four tests of mobility and the physical capabilities of the lower leg muscles. The assessments included measures of muscle strength, muscle activation, and perceived fatigability. Muscle activation was quantified as the ... | ['Aged', 'Aging', 'Female', 'Humans', 'Leg', 'Locomotion', 'Male', 'Motor Activity', 'Muscle Fatigue', 'Muscle, Skeletal', 'Perception', 'Recruitment, Neurophysiological'] | 30,044,670 | [['M01.060.116.100'], ['G07.345.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['G07.568.500', 'G11.427.410.568'], ['F01.145.632', 'G11.427.410.698'], ['G11.427.550'], ['A02.633.567', 'A10.690.552.500'], ['F02.463.593'], ['G07.265.753.760', 'G11.561.601.760']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Formation of heterocyclic amines during cooking of duck meat. | Heterocyclic amines (HAs) are an important class of food mutagens and carcinogens produced in meat cooked at high temperature. In the present study, the effects of various cooking methods: boiling, microwave cooking, charcoal-grilling, roasting, deep-frying and pan-frying on the formation of HAs in duck breast were stu... | ['Amines', 'Animals', 'Carbolines', 'China', 'Chromatography, High Pressure Liquid', 'Cooking', 'Ducks', 'Food Contamination', 'Harmine', 'Heterocyclic Compounds', 'Hot Temperature', 'Imidazoles', 'Maillard Reaction', 'Meat', 'Microwaves', 'Mutagens', 'Quinolines', 'Quinoxalines', 'Solid Phase Extraction', 'Time Factor... | 22,838,849 | [['D02.092'], ['B01.050'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['Z01.252.474.164'], ['E05.196.181.400.300'], ['J01.576.423.200.200'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['D03.132.436.384.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Ischemic necrosis of small bowel following laparoscopic surgery. | BACKGROUND AND OBJECTIVE: Small bowel ischemia following laparoscopy was described recently as a rare fatal complication of the CO2 pneumoperitoneum. Of the 8 cases reported in the surgical literature, 7 were fatal, 1 was not. In this report, we describe the first gynecological case.METHODS: A 34-year-old woman who und... | ['Adult', 'Carbon Dioxide', 'Female', 'Gases', 'Humans', 'Intestinal Perforation', 'Intestine, Small', 'Ischemia', 'Laparoscopy', 'Pneumoperitoneum, Artificial', 'Tissue Adhesions'] | 15,119,662 | [['M01.060.116'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.362'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['A03.556.124.684'], ['C23.550.513'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.370.388.605'], ['C23.550.355.274.840']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrafast dynamics through conical intersections and intramolecular vibrational energy redistribution in styrene. | We report a femtosecond time-resolved photoelectron spectroscopy (TRPES) investigation of internal conversion in the first two excited singlet electronic states of styrene. We find that radiationless decay through an S(1)/S(0) conical intersection occurs on a timescale of ?4 ps following direct excitation to S(1) with ... | ['Algorithms', 'Chemical Phenomena', 'Lasers', 'Models, Molecular', 'Photoelectron Spectroscopy', 'Styrene', 'Ultraviolet Rays'] | 21,069,216 | [['G17.035', 'L01.224.050'], ['G02'], ['E07.632.490', 'E07.710.520'], ['E05.599.595'], ['E05.196.867.618'], ['D02.455.426.559.389.150.750.800'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578.891', 'G16.500.275.063.725.525.600', 'G16.500.750.775.525.600', 'N06.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effect of herpes simplex virus type 1 infection on cytokine gene expression in activated murine peritoneal macrophages. | The intrinsic resistance to herpes simplex virus type 1 (HSV-1) of murine peritoneal macrophages (PM phi) obtained after in vivo infection of different stimuli has been investigated and shown to vary depending on the state of M phi activation. Activation of M phi by C. parvum (CP-M phi) or by an avirulent strain of S. ... | ['Animals', 'Female', 'Gene Expression', 'Herpes Simplex', 'Interleukin-1', 'Interleukin-3', 'Interleukins', 'Macrophage Activation', 'Macrophages', 'Mice', 'Vero Cells'] | 1,514,441 | [['B01.050'], ['G05.297'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D12.644.276.374.410.240.400', 'D12.644.276.374.465.032', 'D12.776.39... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes. | BACKGROUND: Interleukin (IL)-10 levels are increased in dengue virus (DENV)-infected patients with severe disorders. A hypothetical intrinsic pathway has been proposed for the IL-10 response during antibody-dependent enhancement (ADE) of DENV infection; however, the mechanisms of IL-10 regulation remain unclear.PRINCIP... | ['Antibody-Dependent Enhancement', 'Cell Line', 'Dengue', 'Dengue Virus', 'Host-Pathogen Interactions', 'Humans', 'Interleukin-10', 'Monocytes', 'Signal Transduction', 'Virus Replication'] | 25,412,261 | [['G06.920.095', 'G12.113'], ['A11.251.210'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['B04.820.578.344.350.270'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'],... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of heme oxygenase-1 in hydrogen peroxide-induced VEGF synthesis: effect of HO-1 knockout. | Hydrogen peroxide is an important mediator of intracellular signaling, which potently enhances the expression of heme oxygenase-1 (HO-1) and upregulates synthesis of vascular endothelial growth factor (VEGF). The purpose of the present study was to explore the involvement of HO-1 in regulation of H(2)O(2)-mediated indu... | ['Animals', 'Aorta', 'Endothelial Cells', 'Gene Expression Regulation', 'Heme Oxygenase (Decyclizing)', 'Heme Oxygenase-1', 'Hydrogen Peroxide', 'Membrane Proteins', 'Mice', 'Mice, Knockout', 'Vascular Endothelial Growth Factor A'] | 15,596,152 | [['B01.050'], ['A07.015.114.056'], ['A11.436.275'], ['G05.308'], ['D08.811.682.690.708.410'], ['D08.811.682.690.708.410.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania. | Lysates of Leishmania promastigotes can metabolise arachidonic acid to prostaglandins. Prostaglandin production was heat sensitive and not inhibited by aspirin or indomethacin. We cloned and sequenced the cDNA of Leishmania major, Leishmania donovani, and Leishmania tropica prostaglandin F(2alpha) synthase, and overexp... | ['Animals', 'Arachidonic Acid', 'Base Sequence', 'Blotting, Western', 'DNA, Complementary', 'DNA, Protozoan', 'Hydroxyprostaglandin Dehydrogenases', 'Leishmania', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Prostaglandin H2', 'Prostaglandins', 'Prostaglandins H', 'Recombinant... | 12,464,415 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D13.444.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Molecular characterisation and genetic variation of Elephant Endotheliotropic Herpesvirus infection in captive young Asian elephants in Thailand. | Elephant Endotheliotropic Herpesvirus (EEHV) is emerging as a new threat for elephant conservation, since being identified as the cause of severe, often fatal, haemorrhagic disease in young Asian elephants. To describe positive cases and the molecular relatedness of virus detected in elephants in Thailand, we re-examin... | ['Animal Diseases', 'Animals', 'Elephants', 'Female', 'Genes, Viral', 'Genetic Variation', 'Genotype', 'Herpesviridae', 'Herpesviridae Infections', 'Male', 'Phylogeny', 'Thailand'] | 27,503,594 | [['C22'], ['B01.050'], ['B01.050.150.900.649.833.249'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G05.365'], ['G05.380'], ['B04.280.382'], ['C01.925.256.466'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['Z01.252.145.841']] | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
[Diagnostic value of dimerix myelography in postoperative patients]. | Myelography with dimerix was performed and postoperative changes were studied in 88 cases after operations on the intervertebral disks in the lumbar region. The informative value of myelography in recurrence of Schmorl's body is discussed. The use of myelography with a water-soluble contrast medium is indicated in aggr... | ['Adult', 'Arachnoiditis', 'Cicatrix', 'Contrast Media', 'Female', 'Humans', 'Intervertebral Disc Displacement', 'Iothalamic Acid', 'Male', 'Meglumine', 'Meningocele', 'Middle Aged', 'Myelography', 'Postoperative Complications', 'Recurrence', 'Sorbitol', 'Spinal Osteophytosis', 'Tissue Adhesions'] | 7,468,017 | [['M01.060.116'], ['C10.228.614.097'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['D02.241.223.100.400.880.430', 'D02.455.426.559.389.127.375.880.430'], ['D02.033.800.813.550', '... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Capsosomes as Long-Term Delivery Vehicles for Protein Therapeutics. | We report the preparation of polymer capsules containing liposomal subcompartments, termed capsosomes, and their ability for the sustained delivery of protein therapeutics. Capsosomes were formed through the layer-by-layer (LbL) assembly of polymers and protein-loaded liposomes, followed by the formation of a capsule m... | ['Brain-Derived Neurotrophic Factor', 'Capsules', 'Disulfides', 'Drug Liberation', 'Glycerophospholipids', 'Liposomes', 'Muramidase', 'Polymethacrylic Acids'] | 26,155,947 | [['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['D26.255.150'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['D10.570.755.375.760.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.63... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison of compound and cross-modal training on postoperative visual relearning of visual decorticate rats. | The effects of postoperative bimodal compound conditioning and cross-modal transfer of learning on behavior were compared by training rats prior to visual decortication to avoid shock with visual intensity cues. On Postop Day 6, rats were given avoidance training in one of three cue conditions: auditory intensity cues ... | ['Acoustic Stimulation', 'Animals', 'Avoidance Learning', 'Cues', 'Discrimination Learning', 'Electroshock', 'Lighting', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Visual Cortex', 'Visual Perception'] | 8,883,825 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.425.234'], ['F02.463.425.280'], ['E05.723.402.403', 'F04.669.224'], ['N06.230.150.410'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A08.186.211.200.885.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Percutaneous intratumoral injection of cisplatin microspheres in tumor-bearing rats to diminish acute nephrotoxicity. | Poly(D,L-lactide) microspheres loaded with cisplatin (PLA-CDDP MS) were prepared by a solvent evaporation technique for direct intratumoral injection. The microspheres, 50-100 microns, containing 40.04% of cisplatin produce sustained release in vitro. PLA-CDDP MS (6 mg/kg body weight of cisplatin) suspensions were inje... | ['Animals', 'Antineoplastic Agents', 'Cisplatin', 'Drug Carriers', 'Drug Evaluation', 'Injections, Intralesional', 'Kidney', 'Microspheres', 'Rats'] | 8,740,729 | [['B01.050'], ['D27.505.954.248'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D26.255.260', 'E02.319.300.380'], ['E05.290.625', 'E05.337.425'], ['E02.319.267.530.430'], ['A05.810.453'], ['E07.565'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pitfalls in computed tomography of the paranasal sinuses. | The advent of functional endoscopic sinus surgery has created the need for high-quality radiographic images to assess the paranasal sinuses, document the detailed anatomy of the lateral nasal wall and provide an anatomical map allowing safe functional endoscopic sinus surgery. This paper will discuss our experience of ... | ['Artifacts', 'Diagnosis, Differential', 'Endoscopy', 'Evaluation Studies as Topic', 'Humans', 'Sinusitis', 'Tomography, X-Ray Computed'] | 1,774,800 | [['E05.047'], ['E01.171'], ['E01.370.388.250', 'E04.502.250'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.749', 'C08.460.692.752', 'C08.730.749', 'C09.603.692.752'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The relationship of coffee and green tea consumption with high-sensitivity C-reactive protein in Japanese men and women. | BACKGROUND: Circulating high-sensitivity C-reactive protein (CRP) is a good marker of chronic low-grade inflammation. The few studies that have addressed the relationship between coffee consumption and CRP concentrations report inconsistent findings. The authors of this study examined the relationship between coffee an... | ['Aged', 'Alcohol Drinking', 'Body Mass Index', 'C-Reactive Protein', 'Coffee', 'Cohort Studies', 'Female', 'Humans', 'Inflammation', 'Japan', 'Life Style', 'Male', 'Middle Aged', 'Smoking', 'Tea'] | 20,441,477 | [['M01.060.116.100'], ['F01.145.317.269'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Inhibition of myelopoiesis by conditioned medium from cultured canine thymic cells exposed to estrogen. | Therapeutic doses of estrogens can cause fatal bone marrow damage in dogs, which are more sensitive than other species to these myelotoxic effects. Investigations with mice indicated that estrogens did not directly damage the bone marrow progenitor cells, but that the thymus responded to estrogen by producing a factor ... | ['Animals', 'Bone Marrow', 'Bone Marrow Cells', 'Bone Marrow Diseases', 'Cells, Cultured', 'Culture Media, Conditioned', 'Dog Diseases', 'Dogs', 'Estradiol', 'Female', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Thymus Gland'] | 8,214,911 | [['B01.050'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['C15.378.190'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', ... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibodies to protein P in systemic lupus erythematosus. | A synthetic peptide was used to develop an enzyme linked immunosorbent assay (ELISA) to detect antibodies to the ribosomal proteins P0, P1, and P2. Significantly increased levels of IgG antibodies to protein P were found in 16% (18/116) of patients with systemic lupus erythematosus but slightly increased levels were de... | ['Antibodies', 'Antibodies, Antinuclear', 'Antibody Specificity', 'Arthritis, Rheumatoid', 'Blotting, Western', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoglobulin G', 'Lupus Erythematosus, Systemic', 'Mental Disorders', 'Nervous System Diseases', 'Phosphoproteins', 'Ribosomal Proteins'] | 1,586,246 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['G12.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.196.401.143', 'E05.301.300.096', 'E05.47... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transfected DNA is mutated in monkey, mouse, and human cells. | Papovavirus-based shuttle vectors containing the bacterial lacI gene were used to show that a mutation frequency in the range of 1% occurs in lacI when such vectors are transfected into COS7 and CV-1 simian cells, NIH 3T3, 3T6, L, and C127 mouse cells, and human 293 and HeLa cells. This frequency is approximately four ... | ['Animals', 'Cell Division', 'Chromatography, Ion Exchange', 'DNA Restriction Enzymes', 'DNA Transposable Elements', 'DNA, Viral', 'Deoxyribonuclease EcoRI', 'Deoxyribonucleases, Type II Site-Specific', 'Haplorhini', 'Humans', 'Kinetics', 'Mice', 'Mutation', 'Plasmids', 'Simian virus 40', 'Transfection'] | 6,095,032 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.196.181.400.383'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D13.444.308.568'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determinants of Drosophila fushi tarazu mRNA instability. | The fushi tarazu gene is essential for the establishment of the Drosophila embryonic body plan. When first expressed in early embryogenesis, fushi tarazu mRNA is uniformly distributed over most of the embryo. Subsequently, fushi tarazu mRNA expression rapidly evolves into a pattern of seven stripes that encircle the em... | ['Animals', 'Animals, Genetically Modified', 'Base Sequence', 'DNA Primers', 'Drosophila', 'Drosophila Proteins', 'Fushi Tarazu Transcription Factors', 'Gene Expression Regulation, Developmental', 'Genes, Insect', 'Homeodomain Proteins', 'Models, Biological', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'RNA... | 8,649,416 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['D12.776.260.400.155', 'D12.776.930.312'], ['G05.308.310'], ['G05.360.340.02... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evidence for modulation of hydrogen peroxide-induced endothelial barrier dysfunction by nitric oxide in vitro. | Acute effects of the nitric oxide (NO) donors sodium nitroprusside and glyceryl trinitrate on hydrogen peroxide (H2O2)-induced increases in endothelial monolayer permeability to trypan blue-labelled bovine serum albumin have been investigated in vitro. Exposure of bovine pulmonary artery endothelial cell monolayers to ... | ['Animals', 'Cattle', 'Cell Survival', 'Cells, Cultured', 'Endothelium', 'Hydrogen Peroxide', 'In Vitro Techniques', 'Microscopy, Electron', 'Nitric Oxide', 'Nitrites', 'Nitroglycerin', 'Nitroprusside', 'Pulmonary Artery', 'Serum Albumin, Bovine', 'Spectrophotometry, Ultraviolet', 'Trypan Blue'] | 8,832,226 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G04.346'], ['A11.251'], ['A10.272.491'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['E05.481'], ['E01.370.350.515.402', 'E05.595.402'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Post-transplant survival in idiopathic pulmonary fibrosis patients concurrently listed for single and double lung transplantation. | BACKGROUND: Lung transplantation is a widely accepted treatment for patients with end-stage lung disease related to idiopathic pulmonary fibrosis (IPF). However, there are conflicting data on whether double lung transplant (DLT) or single lung transplant (SLT) is the superior therapy in these patients. The purpose of t... | ['Graft Survival', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Lung', 'Lung Transplantation', 'Pulmonary Fibrosis'] | 26,856,664 | [['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.765.500'], ['A04.411'], ['E04.928.600.495', 'E04.936.450.495'], ['C08.381.765']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extragenital Chlamydia and Gonorrhea in Young Black Men Who Have Sex With Men: Missed Treatment Opportunities for Human Immunodeficiency Virus-Infected Men Who Have Sex With Men? | OBJECTIVES: This study of young black men who have sex with men (YBMSM) assessed the prevalence of extragenital chlamydia and gonorrhea among those testing negative for urethral infections, and compared prevalence of both by human immunodeficiency virus (HIV) status.METHODS: A convenience sample of 609 YBMSM was recrui... | ['Adult', 'African Americans', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Cross-Sectional Studies', 'Gonorrhea', 'HIV', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Male', 'Mass Screening', 'Neisseria gonorrhoeae', 'Nucleic Acid Amplification Techniques', 'Rectal Diseases', 'Sexual Behavior', 'Sexual and ... | 29,465,695 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.190.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Coexisting undifferentiated thymic carcinoma and thymic carcinoid tumor. | Thymic carcinoma is an unusual neoplasm, and the undifferentiated type is rare. Thymic carcinoid is also rare. This report describes a patient with coexisting undifferentiated thymic carcinoma and a carcinoid tumor. Both lesions were completely excised. The carcinoid cells showed argyrophilic granules by Grimelius' met... | ['Carcinoid Tumor', 'Humans', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Thymoma', 'Thymus Neoplasms'] | 8,265,883 | [['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.651'], ['C04.557.435.850', 'C04.588.894.949.500', 'C15.604.861.800'], ['C04.588.894.949', 'C15.604.861']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Primary surgical treatment of congenital hip dislocation]. | After discussing some technical aspects of the surgical treatment of the congenital luxation of the hip, the Author reports on 148 of his own cases operated over a period of 8 years. He then goes on to evaluate the follow up also with regard to the age when treated and to describe the more unsuccessful cases. Also in t... | ['Age Factors', 'Casts, Surgical', 'Child, Preschool', 'Evaluation Studies as Topic', 'Female', 'Hip Dislocation, Congenital', 'Humans', 'Infant', 'Male', 'Osteochondritis', 'Osteotomy', 'Time Factors'] | 1,236,287 | [['N05.715.350.075', 'N06.850.490.250'], ['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['M01.060.406.448'], ['E05.337', 'N05.715.360.335'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C05.116.791', 'C05.182.520', 'C17.300.1... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis. | INTRODUCTION: The clinical tests currently in use for obstructive nephropathy (such as renal ultrasonography, differential radionuclide renal scans and urinary creatinine concentration data) are not efficient predictors of the subsequent clinical course. Novel and simple biomarkers are required which, if proven, could ... | ['Acute-Phase Proteins', 'Biomarkers', 'Case-Control Studies', 'Child, Preschool', 'Enzyme-Linked Immunosorbent Assay', 'Fatty Acid-Binding Proteins', 'Female', 'Follow-Up Studies', 'Hepatitis A Virus Cellular Receptor 1', 'Humans', 'Hydronephrosis', 'Infant', 'Infant, Newborn', 'Lipocalin-2', 'Lipocalins', 'Male', 'Me... | 26,096,437 | [['D12.776.124.050'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.157.170'], ['E05.318.372.500.750.249', 'N05.715.360.330.50... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer. | KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognosis. In the present study, we selected a homogeneous cohort including 139 patients of advanced high-grade serous ovarian cancer (FIGO stage III/IV) and assessed the mRNA levels of KLK9, 10, 11, and 15 in tumor tissue by q... | ['Disease Progression', 'Female', 'Humans', 'Kallikreins', 'Ovarian Neoplasms', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Survival Rate'] | 29,095,848 | [['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.959.350.442', 'D12.776.124.125.597', 'D23.119.597'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['D13.444.735.544'], ['E05.393.620.500.706... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Proteolytic activities of two types of mannose-binding lectin-associated serine protease. | Mannose (or mannan)-binding lectin (MBL) is an oligomeric serum lectin that plays a role in innate immunity by activating the complement system. In human, two types of MBL-associated serine protease (MASP-1 and MASP-2) and a truncated protein of MASP-2 (small MBL-associated protein; sMAP or MAp19) are complexed with MB... | ['Binding, Competitive', 'Carrier Proteins', 'Collectins', 'Complement Activation', 'Complement C1 Inactivator Proteins', 'Dose-Response Relationship, Immunologic', 'Enzyme Activation', 'Humans', 'Hydrolysis', 'Lectins', 'Mannose', 'Mannose-Binding Protein-Associated Serine Proteases', 'Serine Endopeptidases', 'Serine ... | 10,946,292 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D12.776.157'], ['D12.776.503.280.249'], ['G12.274'], ['D12.644.861.140', 'D12.776.124.486.274.920.250', 'D12.776.872.140'], ['G12.300'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['D12.776.503'], ['D09.947.875.359.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression profiling of claudins in the human gastrointestinal tract in health and during inflammatory bowel disease. | BACKGROUND: Claudins, being part of the tight junction protein family, partially determine the integrity and paracellular permeability of the intestinal epithelium. The aim of this study was twofold. First, the authors set out to create an overview of claudin mRNA expression along the proximal-distal axis of the health... | ['Adolescent', 'Adult', 'Aged', 'Case-Control Studies', 'Claudins', 'Colitis, Ulcerative', 'Crohn Disease', 'Female', 'Gene Expression Profiling', 'Humans', 'Intestinal Mucosa', 'Male', 'Middle Aged', 'Protein Isoforms', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Young Adult'] | 23,205,909 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.776.543.940.200'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E05.393.332'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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