Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Esophageal cancer developed after gastrectomy. | Between 1965 and 1983 we treated 129 patients with primary esophageal squamous cell carcinoma. Of these patients, 12 (9.3%) had previously undergone partial gastrectomy and six manifested tumors in the lower thoracic esophagus. Esophagitis of the noncancerous esophageal mucosa surrounding the cancer was confirmed in th... | ['Adult', 'Age Factors', 'Aged', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Gastrectomy', 'Humans', 'Male', 'Middle Aged', 'Nutritional Physiological Phenomena', 'Retrospective Studies', 'Risk', 'Time Factors'] | 3,942,003 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predictors of event-free survival after percutaneous mitral commissurotomy. | OBJECTIVE: To assess the long term functional result after percutaneous mitral commissurotomy and identify the predictors of event-free survival following 10 years of experience.DESIGN: Analysis of clinical, echocardiographic, and haemodynamic variables at baseline and after the procedure by univariate and multivariate... | ['Age Factors', 'Aged', 'Analysis of Variance', 'Catheterization', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Mitral Valve Stenosis', 'Risk Factors', 'Survival Rate'] | 9,875,112 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E02.148', 'E05.157'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.3... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
SecB binds only to a late native-like intermediate in the folding pathway of barstar and not to the unfolded state. | SecB is a cytosolic, tetrameric chaperone of Escherichia coli which maintains precursor proteins in a translocation competent state. We have investigated the effect of SecB on the refolding kinetics of the small protein barstar in 1 M guanidine hydrochloride at pH 7.0 and 25 degreesC using fluorescence spectroscopy. We... | ['Bacterial Proteins', 'Enzyme Inhibitors', 'Escherichia coli', 'Guanidine', 'Kinetics', 'Molecular Chaperones', 'Protein Binding', 'Protein Denaturation', 'Protein Folding', 'Ribonucleases', 'Spectrometry, Fluorescence', 'Thermodynamics'] | 9,772,175 | [['D12.776.097'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.078.370.472'], ['G01.374.661', 'G02.111.490'], ['D12.776.580'], ['G02.111.679', 'G03.808'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G01.154.651', 'G02.111.688'], ['D08.811.277.352.700'], ['E05.196.712.516.600.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MISET: an immunological technique for the serodiagnosis of Cryptobia salmositica (Sarcomastigophora: Kinetoplastida) infection in Oncorhynchus mykiss. | A serodiagnostic technique, microscopic immuno-substrate-enzyme technique (MISET), is described using the Cryptobia-Oncorhynchus mykiss system. The reactions of specific antibodies, phosphatase-labeled antibody, and substrate with subsequent color development on the parasite (cell membrane, flagella, kinetoplast, and n... | ['Animals', 'Antibodies, Protozoan', 'Eukaryota', 'Fish Diseases', 'Fluorescent Antibody Technique', 'Immunoenzyme Techniques', 'Protozoan Infections', 'Protozoan Infections, Animal', 'Salmon', 'Trout'] | 2,191,102 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['B01'], ['C22.362'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early pregnancy blood lead levels and the risk of premature rupture of the membranes. | To clarify the effects of lead on fetal premature rupture of the membranes (PROM), blood lead concentrations were measured using inductively coupled plasma-mass spectrometry in 332 women, aged 16-35 years, during their early pregnancy period (8-12 weeks). Blood lead concentrations were significantly higher in the 36 PR... | ['Adolescent', 'Adult', 'Case-Control Studies', 'Environmental Pollutants', 'Female', 'Fetal Membranes, Premature Rupture', 'Humans', 'Lead', 'Logistic Models', 'Pregnancy', 'Pregnancy Trimester, First', 'Risk Factors', 'Spectrophotometry, Atomic', 'Young Adult'] | 20,576,532 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D27.888.284'], ['C13.703.420.339'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.435', 'D01.552.544.435'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effects of cromolyn sodium on intestinal ischemia-reperfusion injury by inhibiting PAR-2 expression in rats]. | OBJECTIVE: To explore the effects of cromolyn sodium (CS) on intestinal ischemia-reperfusion (IIR) and its relationship with mast cell activation and protease-activated receptor 2 (PAR-2) expression.METHODS: A total of 32 SD rats were randomly divided into 4 groups: sham-operated (S), intestinal ischemia reperfusion (I... | ['Animals', 'Cromolyn Sodium', 'Female', 'Intestinal Mucosa', 'Intestines', 'Male', 'Mast Cells', 'Rats', 'Rats, Sprague-Dawley', 'Receptor, PAR-2', 'Reperfusion Injury'] | 23,290,058 | [['B01.050'], ['D03.383.663.283.266.300', 'D03.633.100.150.266.300'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['A11.329.427', 'A15.382.652'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D12.776.543.750.695.035', 'D12.776.543.750.792.249'], ['C14.907.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A proposed evaluation of a primary health care approach to control schistosomiasis in Zimbabwe. | Zimbabwe has undertaken a national control programme for schistosomiasis. Targets have been set for the next five year period and implementation of the programme will be through the primary health care system. Improved water supplies and sanitation are seen as a major part of the programme which will be supplemented by... | ['Adolescent', 'Adult', 'Animals', 'Child', 'Child, Preschool', 'Community Health Workers', 'Humans', 'Infant', 'Middle Aged', 'Patient Education as Topic', 'Primary Health Care', 'Sanitation', 'Schistosomiasis haematobia', 'Schistosomiasis mansoni', 'Snails', 'Water Supply', 'Zimbabwe'] | 3,092,333 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['M01.526.485.067.080', 'N02.360.067.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['I02.233.332.500', 'N02.421.726.407.680'], ['N04.590.233.727'], ['H02.229.782', 'N06.850.780.200.800',... | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Genomics and microarray for detection and diagnostics. | Genomics provided biomedical scientists an inventory of all genes and sequences present in a living being. This provides an unique opportunity to the scientists to predict and study biological functions of these genes. The changes in the gene expression regulated by genomic sequences therefore reflect changes in the mo... | ['Drug Design', 'Genomics', 'Humans', 'Microarray Analysis', 'Neoplasms'] | 15,704,334 | [['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.588.570'], ['C04']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A 30 kDa functional size for the erythrocyte water channel determined in situ by radiation inactivation. | The functional unit size of the water channel in rabbit erythrocytes was assessed using target size analysis following radiation inactivation. Using Radiochromic nylon dosimetry, accurate values of accumulated dose yielded an absolute target analysis, leading to direct determination of molecular size. The erythrocyte w... | ['Acetylcholinesterase', 'Alkaline Phosphatase', 'Animals', 'Dose-Response Relationship, Radiation', 'Erythrocyte Membrane', 'Ion Channels', 'Kidney Tubules, Proximal', 'Kinetics', 'Microvilli', 'Molecular Weight', 'Rabbits'] | 1,375,458 | [['D08.811.277.352.100.170.176'], ['D08.811.277.352.650.035'], ['B01.050'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['A05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10:interferon-gamma-secreting cells in the peripheral blood. | OBJECTIVE: To compare the phenotype and frequency of cells that actively secrete type 1 and type 2 cytokines in systemic lupus erythematosus (SLE) patients (n = 46), versus normal controls (n = 60).METHODS: ELISPOT analysis of freshly isolated peripheral blood mononuclear cells (PBMC).RESULTS: T cells were the major so... | ['Adult', 'Cytokines', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Immunophenotyping', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-2', 'Interleukin-6', 'Leukocytes, Mononuclear', 'Lupus Erythematosus, Systemic', 'Macrophages', 'Male', 'Middle Aged', 'Monocytes', 'Phytohemagglutinins', 'Predictive Value of Te... | 8,607,886 | [['M01.060.116'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Partitioning of exhaled NO in ventilated patients undergoing cardiac surgery. | The change in exhaled NO after cardio-pulmonary bypass remains controversial. The aims were to determine whether exhaled NO sources (alveolar or bronchial) are modified after bypass, and whether mechanical ventilation (MV) settings during bypass modify exhaled NO changes. Thirty-two patients were divided into three gro... | ['Aged', 'Aged, 80 and over', 'Biomarkers', 'Bronchi', 'Cardiac Surgical Procedures', 'Cardiopulmonary Bypass', 'Exhalation', 'Female', 'Humans', 'Lung Injury', 'Male', 'Middle Aged', 'Nitric Oxide', 'Positive-Pressure Respiration', 'Pulmonary Alveoli', 'Respiration, Artificial', 'Respiratory Dead Space'] | 20,219,698 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['A04.411.125'], ['E04.100.376', 'E04.928.220'], ['E04.292.413'], ['G09.772.705.700.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.520', 'C26.891.554'], ['M01.060.116.630'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diagnosis and subclassification of lymphomas and non-neoplastic lesions involving mediastinal lymph nodes using endobronchial ultrasound-guided transbronchial needle aspiration. | INTRODUCTION: The value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been established for staging mediastinal lymph nodes in lung carcinoma patients with radiologically enlarged lymph nodes, but its utility for evaluation of primary lymph node disorders is not well defined. The ob... | ['Adult', 'Aged', 'Aged, 80 and over', 'Diagnosis, Differential', 'Endoscopic Ultrasound-Guided Fine Needle Aspiration', 'Female', 'Granuloma', 'Hodgkin Disease', 'Humans', 'Immunophenotyping', 'Lymph Nodes', 'Lymphadenitis', 'Lymphatic Diseases', 'Lymphoma', 'Male', 'Mediastinum', 'Middle Aged', 'Young Adult'] | 21,630,485 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.171'], ['E01.370.225.500.384.100.119.500.500', 'E01.370.225.500.384.100.370.500', 'E01.370.225.998.054.119.500.500', 'E01.370.225.998.054.370.500', 'E01.370.350.850.855.500', 'E01.370.388.100.100.500.500', 'E01.370.388.100.370.500', 'E04.074.119.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A murine model of ex vivo angiogenesis using aortic disks grown in fibrin clot. | The rat aortic ring model is well utilized for evaluation of angiogenesis. We report here an alternative assay employing an ex vivo mouse aorta angiogenesis model that can be extensively manipulated and serially evaluated using digital-assisted image analysis. Mouse aortas were harvested, cut into 2-mm disks, and cultu... | ['Animals', 'Aorta', 'Cell Proliferation', 'Cell Separation', 'Endostatins', 'Endothelium, Vascular', 'Fibrin', 'Flow Cytometry', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'Mice', 'Microcirculation', 'Neovascularization, Pathologic', 'Neovascularization, Physiologic', 'Physiology', 'Platelet Endoth... | 15,501,237 | [['B01.050'], ['A07.015.114.056'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D12.644.276.100.450.750', 'D12.776.467.100.450.750', 'D12.776.860.300.250.400.537.500', 'D23.529.100.450.750'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.124.270'], ['E01.370.2... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Platelet aggregation: its relation with ADP-induced fibrinogen binding to platelets and ADP-related membrane enzyme activities. | The receptor for ADP on the platelet membrane, which triggers exposure of fibrinogen-binding sites and platelet aggregation, has not yet been identified. Two enzymes with which ADP interacts on the platelet surface, an ecto-ATPase and nucleosidediphosphate kinase, have been proposed as possible receptors for ADP in ADP... | ['Adenosine Diphosphate', 'Adenosine Monophosphate', 'Adenosine Triphosphate', 'Blood Platelets', 'Cell Membrane', 'Creatine Kinase', 'Fibrinogen', 'Humans', 'Phosphocreatine', 'Platelet Aggregation', 'Platelet Membrane Glycoproteins', 'Receptors, Cell Surface'] | 6,088,225 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.118.188', 'A15.145.229.188'], ['A11.284.149'], ['D08.811.913.696.640.150'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploiting E. coli auxotrophs for leucine, valine, and threonine specific methyl labeling of large proteins for NMR applications. | A simple and cost effective method to independently and stereo-specifically incorporate [(1)H,(13)C]-methyls in Leu and Val in proteins is presented. Recombinant proteins for NMR studies are produced using a tailored set of auxotrophic E. coli strains. NMR active isotopes are routed to either Leu or Val methyl groups f... | ['Escherichia coli Proteins', 'Isotope Labeling', 'Leucine', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Protein Conformation', 'Recombinant Proteins', 'Threonine', 'Valine'] | 27,255,761 | [['D12.776.097.275'], ['E05.522'], ['D12.125.070.637', 'D12.125.142.441'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570.820.709'], ['D12.776.828'], ['D12.125.142.815', 'D12.125.154.900'], ['D12.125.070.950', 'D12.125.142.930']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Carcinomatous perforation of the sigmoid colon presenting as a thigh mass. | We report a patient presenting with a left psoas abscess causing necrotizing fasciitis of the upper thigh. The patient underwent exploration of the left thigh through a medial approach, confirming necrotizing fasciitis of the adductor compartment and the femoral triangle. The infective process also involved the left ps... | ['Aged', 'Diagnosis, Differential', 'Fasciitis, Necrotizing', 'Fatal Outcome', 'Female', 'Humans', 'Intestinal Perforation', 'Psoas Abscess', 'Radiography', 'Sigmoid Neoplasms'] | 8,879,743 | [['M01.060.116.100'], ['E01.171'], ['C05.321.550'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['C01.830.025.700'], ['E01.370.350.700'], ['C04.588.274.476.411.307.180.800', 'C06.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Being Fully Present: Gains Patients Attribute to a Telephone-Delivered Parenting Program for Child-Rearing Mothers With Cancer. | BACKGROUND: Oncology nurses can assist patients in gaining skills and confidence in multiple areas of illness self-management, including parenting skills. Child-rearing parents with cancer are a unique population because they must self-manage their illness and also help their child manage the intrusion of cancer on eve... | ['Adult', 'Breast Neoplasms', 'Child', 'Child Rearing', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mother-Child Relations', 'Neoplasms', 'Nursing Evaluation Research', 'Parenting', 'Qualitative Research', 'Telephone'] | 28,591,011 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['M01.060.406'], ['F01.318'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.263.370.290.170'], ['C04'], ['H01.770.644.145.390.432', 'H02.478.395.432', 'N04.590.233.508.613.432'], ['F01.829.263.370.310'], ['H01.7... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Trichotillomania and related disorders in children and adolescents. | Eleven chronic hair pullers, 11 subjects with obsessive-compulsive disorders (OCD), and 11 subjects with a non-OCD anxiety disorder were assessed with structured interviews and the Child Behavior Checklist (CBCL). Only 4 hair pullers (36%) reported both rising tension and relief with hair pulling. Each group had signif... | ['Adolescent', 'Case-Control Studies', 'Child', 'Diagnosis, Differential', 'Female', 'Humans', 'Internal-External Control', 'Male', 'Manuals as Topic', 'Mental Disorders', 'Multivariate Analysis', 'Trichotillomania'] | 9,200,885 | [['M01.060.057'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['L01.178.682.192.609', 'L01.178.820.500'], ['F03'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Free cortisol in sepsis and septic shock. | BACKGROUND: Severe sepsis activates the hypothalamopituitary axis, increasing cortisol production. In some studies, hydrocortisone substitution based on an adrenocorticotropic hormone-stimulation test or baseline cortisol measurement has improved outcome. Because only the free fraction of cortisol is active, measuremen... | ['Adrenal Cortex Function Tests', 'Adrenal Insufficiency', 'Adult', 'Biomarkers', 'Female', 'Finland', 'Hospital Mortality', 'Humans', 'Hydrocortisone', 'Kaplan-Meier Estimate', 'Male', 'Predictive Value of Tests', 'Prospective Studies', 'Sepsis', 'Severity of Illness Index', 'Shock, Septic', 'Treatment Outcome'] | 18,499,615 | [['E01.370.374.050'], ['C19.053.500'], ['M01.060.116'], ['D23.101'], ['Z01.542.816.186'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Collaboration in investigator initiated public health nursing research: university and agency considerations. | There is a significant difference in the collaborative process between whether a public health nursing research project is requested (of the researchers) by the agency or if it is conceived by an outside investigator. This article discusses the underlying concepts of negotiation, mutuality, and respect that support the... | ['Community-Institutional Relations', 'Humans', 'Interinstitutional Relations', 'Nursing Research', 'Planning Techniques', 'Public Health Nursing', 'Research Personnel', 'Universities'] | 7,971,692 | [['N04.452.822.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.822.400'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['N04.452.718'], ['H02.478.676.755'], ['M01.526.839'], ['I02.783.830', 'J03.832.830']] | ['Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
Effects of endurance training on glucose tolerance and plasma lipid levels in older men and women. | Eleven healthy men and women (63 +/- 1 years) participated in a 12-month endurance-training program to determine the effects of low-intensity and high-intensity training on glucose tolerance and plasma lipids in older persons. Plasma glucose, insulin, and C-peptide concentrations were measured for three hours after ing... | ['Aged', 'Blood Glucose', 'C-Peptide', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Lipids', 'Lipoproteins, HDL', 'Lipoproteins, LDL', 'Male', 'Middle Aged', 'Oxygen', 'Physical Education and Training', 'Respiration'] | 6,376,837 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Chemical nature of stochastic generation of protein-based carbonyls: metal-catalyzed oxidation versus modification by products of lipid oxidation. | An assessment of 2,4-dinitrophenylhydrazine (DNPH)-detectable protein-based carbonyls is one of the most common assays used to quantify oxidative stress in vitro and in vivo. In this study, we compared, for the lipid-binding protein beta-lactoglobulin, the extent to which carbonyl reactivity could be introduced by adve... | ['Catalysis', 'Chromatography, High Pressure Liquid', 'Electrophoresis, Polyacrylamide Gel', 'Ketones', 'Lactoglobulins', 'Lipid Peroxidation', 'Lipids', 'Metals', 'Oxidation-Reduction', 'Peptide Mapping', 'Spectrometry, Mass, Electrospray Ionization', 'Stochastic Processes', 'Trypsin'] | 17,226,935 | [['G02.130'], ['E05.196.181.400.300'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.522'], ['D12.776.256.159.750.816.500', 'D12.776.377.457'], ['G02.111.515', 'G03.295.531.587'], ['D10'], ['D01.552'], ['G02.700', 'G03.295.531'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Coenzyme B12 Repurposed for Photoregulation of Gene Expression. | Old cofactor, new tricks: In enzymes, coenzyme B12 has a well-known function as a radical initiator through homolysis of the Co-C bond. It has recently been shown that nature has repurposed this cofactor as a photosensitive switch for the regulation of bacterial carotenoid biosynthesis. Co-C bond breakage is again the ... | ['Bacterial Proteins', 'Binding Sites', 'Cobamides', 'DNA', 'Gene Expression', 'Molecular Dynamics Simulation', 'Photoreceptors, Microbial', 'Promoter Regions, Genetic', 'Protein Binding', 'Protein Structure, Quaternary', 'Thermus thermophilus'] | 27,010,518 | [['D12.776.097'], ['G02.111.570.120'], ['D03.383.129.578.840.437.777.270', 'D03.633.400.909.437.777.270', 'D04.345.783.437.777.270', 'D08.211.175'], ['D13.444.308'], ['G05.297'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D12.776.752'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chondrogenic differentiation of adult dermal fibroblasts. | Cell sources for generation of articular cartilage ex vivo are limited. To explore options other than stem cells, dermal fibroblasts were tested for their developmental potential when cultured on the cartilage matrix proteoglycan, aggrecan. A previous study suggested such an effort would be successful (M. M. French et ... | ['Aggrecans', 'Animals', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'Cells, Cultured', 'Chondrocytes', 'Collagen', 'Culture Techniques', 'Extracellular Matrix', 'Extracellular Matrix Proteins', 'Fibroblasts', 'Lectins, C-Type', 'Proteoglycans', 'Rabbits', 'Skin', 'Tissue Engineering'] | 14,964,721 | [['D09.698.735.200.500', 'D12.776.395.650.750.687.100', 'D12.776.503.280.437.100', 'D12.776.860.300.140'], ['B01.050'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['A11.251'], ['A11.329.171'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E05.481.500'], ['A11... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Schedule of stereotactic radiotherapy: a study considering the factors of repair and cell proliferation]. | Stereotactic radiosurgery (SRS: stereotactic irradiation [STI] delivered in a single high dose) was initially developed by Leksell for non-malignant brain lesions, but there has been increasing interest in using it to treat small primary brain tumors or metastases. Recently, stereotactic radiotherapy (SRT: fractionated... | ['Brain', 'Brain Neoplasms', 'Cell Division', 'Humans', 'Radiosurgery', 'Stereotaxic Techniques'] | 9,778,938 | [['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['E04.525.800', 'E05.873']] | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. | A mysterious outbreak of atypical pneumonia in late 2019 was traced to a seafood wholesale market in Wuhan of China. Within a few weeks, a novel coronavirus tentatively named as 2019 novel coronavirus (2019-nCoV) was announced by the World Health Organization. We performed bioinformatics analysis on a virus genome from... | ['Amino Acid Sequence', 'Betacoronavirus', 'COVID-19', 'China', 'Coronavirus Infections', 'Genome, Viral', 'Humans', 'Phylogeny', 'Pneumonia, Viral', 'SARS-CoV-2', 'Sequence Analysis, Protein', 'Travel', 'Viral Proteins'] | 31,987,001 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['Z01.252.474.164'], ['C01.925.782.600.550.200'], ['G05.360.340.358.840'], ['B01.050.150.90... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
Role of spontaneous physical activity in prediction of susceptibility to activity based anorexia in male and female rats. | Anorexia nervosa (AN) is a chronic eating disorder affecting females and males, defined by body weight loss, higher physical activity levels and restricted food intake. Currently, the commonalities and differences between genders in etiology of AN are not well understood. Animal models of AN, such as activity-based ano... | ['Animals', 'Anorexia', 'Disease Models, Animal', 'Disease Susceptibility', 'Female', 'Male', 'Motor Activity', 'Physical Conditioning, Animal', 'Rats', 'Running', 'Weight Loss'] | 24,912,135 | [['B01.050'], ['C23.888.821.108'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.687', 'G07.100.250'], ['F01.145.632', 'G11.427.410.698'], ['G11.427.410.698.277.280'], ['B01.050.150.900.649.313.992.635.505.700'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Use of an affinity label to probe the function of the NADPH binding component of the respiratory burst oxidase of human neutrophils. | The respiratory burst oxidase of neutrophils can be activated in a cell-free system in which solubilized membranes, cytosol, and Mg2+ are required and in which sodium dodecyl sulfate is used to convert the dormant oxidase to an active form. The 2',3'-dialdehyde analog of NADPH was used as an affinity label for the cyto... | ['Affinity Labels', 'Cell-Free System', 'Cytosol', 'Enzyme Activation', 'Granulomatous Disease, Chronic', 'Humans', 'Kinetics', 'NADH, NADPH Oxidoreductases', 'NADP', 'NADPH Oxidases', 'Neutrophils', 'Oxidation-Reduction', 'Peroxides', 'Protein Binding'] | 2,745,440 | [['D27.720.470.410.080'], ['A11.284.835.168'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G02.111.263', 'G03.328'], ['C15.378.553.774.535', 'C16.320.322.233', 'C20.673.774.535'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.608'], ['D03.633... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomical Organization and Spatiotemporal Firing Patterns of Layer 3 Neurons in the Rat Medial Entorhinal Cortex. | Layer 3 of the medial entorhinal cortex is a major gateway from the neocortex to the hippocampus. Here we addressed structure-function relationships in medial entorhinal cortex layer 3 by combining anatomical analysis with juxtacellular identification of single neurons in freely behaving rats. Anatomically, layer 3 app... | ['Action Potentials', 'Animals', 'Calbindins', 'Entorhinal Cortex', 'Pyramidal Cells', 'Rats', 'Rats, Wistar', 'Theta Rhythm'] | 26,354,904 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D12.776.157.125.090'], ['A08.186.211.180.590.750.225', 'A08.186.211.180.710.225', 'A08.186.211.200.885.287.500.382.750.225', 'A08.186.211.200.885.287.500.620.562', 'A08.186.211.200.885.287.500.814.695.374', 'A08.186.211.200.885.287.750.562'], ['A08.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imaging live cell in micro-liquid enclosure by X-ray laser diffraction. | Emerging X-ray free-electron lasers with femtosecond pulse duration enable single-shot snapshot imaging almost free from sample damage by outrunning major radiation damage processes. In bioimaging, it is essential to keep the sample close to its natural state. Conventional high-resolution imaging, however, suffers from... | ['Actinobacteria', 'Animals', 'Imaging, Three-Dimensional', 'Lasers', 'Scattering, Radiation', 'X-Ray Diffraction'] | 24,394,916 | [['B03.510.024', 'B03.510.460.400.400.049'], ['B01.050'], ['E01.370.350.400', 'L01.224.308.410'], ['E07.632.490', 'E07.710.520'], ['E05.196.822', 'G01.867'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Urethral carcinosarcoma from bladder carcinosarcomatous lesions: analysis of clinicopathological features. | Carcinosarcoma (CS) of the bladder is a rare malignancy of the genitourinary tract that is highly aggressive with unfavorable prognoses. Data regarding the epidemiological and clinicopathological characteristics of CS of the urinary bladder have been limited due to the low reported incidence of the tumor. In particular... | ['Aged', 'Carcinosarcoma', 'Humans', 'Male', 'Neoplasm Invasiveness', 'Urethral Neoplasms', 'Urinary Bladder Neoplasms'] | 19,222,894 | [['M01.060.116.100'], ['C04.557.435.290', 'C04.557.450.795.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.645', 'C23.550.727.645'], ['C04.588.945.947.945', 'C12.758.820.937', 'C12.777.767.601', 'C13.351.937.820.890', 'C13.351.968.767.601'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Distinct binding properties of eaeA-negative verocytotoxin-producing Escherichia coli of serotype O113:H21. | Infection of humans with verotoxin-producing Escherichia coli (VTEC) O113:H21 is associated with clinical features comparable to those associated with infection with attaching and effacing VTEC strains including those of serotype O157:H7. We have shown previously that the adhesion phenotype of VTEC O157:H7 is influence... | ['Actinin', 'Adhesins, Bacterial', 'Bacterial Adhesion', 'Bacterial Outer Membrane Proteins', 'Bacterial Toxins', 'Carrier Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Genes, Bacterial', 'Humans', 'Phosphotyrosine', 'Shiga Toxin 1', 'Tyrosine', 'Virulence'] | 7,518,809 | [['D05.750.078.730.248', 'D12.776.210.500.095', 'D12.776.220.525.250'], ['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['G06.099.050'], ['D12.776.097.120', 'D12.776.543.100'], ['D23.946.123'], ['D12.776.157'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.360.340... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stability-indicating chromatographic methods for the determination of sertindole. | In this work, two chromatographic methods have been developed and validated for the determination of sertindole (an antipsychotic agent) in the presence of its oxidative degradation product. Sertindole was subjected to stress stability studies, including acid, alkali, oxidative, photolytic and thermal degradation. The ... | ['Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Drug Stability', 'Imidazoles', 'Indoles', 'Reproducibility of Results'] | 23,733,912 | [['E05.196.181.400.300'], ['E05.196.181.400.537'], ['E05.916.330'], ['D03.383.129.308'], ['D03.633.100.473'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Actions of the opioid antagonist, nalmefene, and congeners on reperfusion cardiac arrhythmias and regional left coronary blood flow. | Opioid antagonists have been shown to prevent the occurrence of lethal arrhythmias following coronary reperfusion. In this study, we have examined the effect of a new, long-lasting, potent opioid antagonist, nalmefene, and congeners in the prevention of reperfusion arrhythmias in dogs. Nalmefene given at a dose of 1 mg... | ['Animals', 'Arrhythmias, Cardiac', 'Coronary Circulation', 'Dogs', 'Female', 'Injections, Intravenous', 'Male', 'Myocardial Reperfusion', 'Naltrexone', 'Narcotic Antagonists', 'Premedication', 'Time Factors', 'Ventricular Function, Left'] | 2,277,810 | [['B01.050'], ['C14.280.067', 'C23.550.073'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E04.100.700.600', 'E05.680.730.600'], ['D03.132.577.249.706.550', 'D03.605.497.750.550', 'D03.633.400.686.750.550', 'D04.615.723.795.706.550'], ['D27.505.696.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of body mass index and other body composition parameters in early post-transplant complications in patients undergoing allogeneic stem cell transplantation with busulfan-cyclophosphamide conditioning. | Patients with impaired nutritional status may show increased risk of hematopoietic stem cell transplantation (HSCT)-related complications. This study was conducted to determine whether body mass index (BMI) and other body composition parameters, such as lean body mass index (LBMI) and body fat mass (BFM), are associate... | ['Adolescent', 'Adult', 'Antineoplastic Agents, Alkylating', 'Body Composition', 'Body Mass Index', 'Busulfan', 'Cyclophosphamide', 'Female', 'Humans', 'Leukemia', 'Male', 'Middle Aged', 'Nutritional Status', 'Retrospective Studies', 'Stem Cell Transplantation', 'Survival Analysis', 'Transplantation Conditioning', 'Tra... | 22,160,835 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D02.033.455.125.125', 'D02.455.326.146.100.050.500.100', 'D02.886.645.600.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring. | The 4-piperidyl moiety and the pyrazole ring in 1-(3-chlorophenyl)-5-(4-phenoxyphenyl)-3-(4-piperidyl)pyrazole 2, which has previously shown improved DNA gyrase inhibition and target-related antibacterial activity, were transformed to other groups and the in vitro antibacterial activity of the synthesized compounds was... | ['Anti-Bacterial Agents', 'Azoles', 'DNA Gyrase', 'Enzyme Inhibitors', 'Microbial Sensitivity Tests', 'Staphylococcus aureus', 'Topoisomerase II Inhibitors'] | 15,465,328 | [['D27.505.954.122.085'], ['D03.383.129'], ['D08.811.399.403.741.149', 'D12.776.097.237'], ['D27.505.519.389'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100'], ['D27.505.519.389.892.750', 'D2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A clinic within a general hospital for the assessment of urgent psychiatric problems. | Of 100 consecutive referrals to a clinic for urgent psychiatric assessment only a third (34 patients) were considered to warrant such urgent attention. In 29 of the 34 cases the patient's behaviour--either intent to harm himself or unpredictable behaviour that alarmed the referring agent--was the most important conside... | ['Emergency Service, Hospital', 'Emergency Services, Psychiatric', 'Evaluation Studies as Topic', 'Female', 'Hospitals, General', 'Humans', 'London', 'Male', 'Mental Health Services', 'Patient Admission', 'Personality Disorders', 'Psychotic Disorders', 'Referral and Consultation', 'Social Behavior Disorders'] | 72,968 | [['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['F04.408.525', 'N02.421.297.200'], ['E05.337', 'N05.715.360.335'], ['N02.278.421.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.433.553', 'Z01.542.363.300.553'], ['F04.408', 'N02.421.461'], ['E02.760.400.600', 'N02.421.585.400.6... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Abnormal glucose metabolism among older men with or at risk of HIV infection. | OBJECTIVES: To determine factors associated with diabetes, insulin resistance, and abnormal glucose tolerance in older men with or at risk of HIV infection.METHODS: Diabetes was assessed by self-report in 643 men >or=49 years old with or at risk of HIV infection. In a subset of 216 men without previously diagnosed diab... | ['Antiretroviral Therapy, Highly Active', 'Body Composition', 'Cohort Studies', 'Diabetes Complications', 'Diabetes Mellitus', 'Glucose Intolerance', 'Glucose Tolerance Test', 'HIV Infections', 'HIV Protease Inhibitors', 'Humans', 'Insulin Resistance', 'Interviews as Topic', 'Male', 'Middle Aged', 'Risk Factors', 'Subs... | 16,903,984 | [['E02.319.310.075'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C19.246.099'], ['C18.452.394.750', 'C19.246'], ['C18.452.394.952.500'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['C01.221.250.875', 'C01.221.81... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Fullerene C60 functionalized ã-Fe2O3 magnetic nanoparticle: Synthesis, characterization, and biomedical applications. | Hybrid magnetic nanoparticles composed from C60 fullerene and ã-Fe2O3 were synthesized by hydrothermal method. XRD, FT-IR, VSM, SEM, and HR-TEM were employed for characterizations. The magnetic saturation value of C60-ã-Fe2O3 magnetic nanoparticles was 66.5 emu g(-1). Concentration of Fe in nanoparticles as determined ... | ['Adsorption', 'Anti-Inflammatory Agents, Non-Steroidal', 'Drug Carriers', 'Ferric Compounds', 'Flurbiprofen', 'Fullerenes', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Magnetite Nanoparticles', 'Particle Size'] | 25,118,710 | [['G01.030', 'G02.020'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D26.255.260', 'E02.319.300.380'], ['D01.490.100'], ['D02.241.081.751.161', 'D02.455.426.559.389.185.350'], ['D01.268.150.250', 'J01.637.512.600.612.350'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Temporal expression of inflammatory mediators in brain basilar artery vasculitis and cerebrospinal fluid of rabbits with coccidioidal meningitis. | Strokes due to transmural vasculitis associated with coccidioidal meningitis result in significant morbidity and mortality. The immunological and inflammatory processes responsible are poorly understood. To determine the inflammatory mediators, i.e. cytokines, chemokines, iNOS, matrix metalloproteinase-9 (MMP-9), that ... | ['Animals', 'Basilar Artery', 'Brain', 'Coccidioides', 'Coccidioidomycosis', 'Cytokines', 'Disease Models, Animal', 'Inflammation Mediators', 'Male', 'Matrix Metalloproteinase 9', 'Meningitis, Fungal', 'RNA, Messenger', 'Rabbits', 'Reverse Transcriptase Polymerase Chain Reaction', 'Spinal Cord', 'Up-Regulation', 'Vascu... | 16,487,245 | [['B01.050'], ['A07.015.114.106'], ['A08.186.211'], ['B01.300.381.230'], ['C01.150.703.203'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D23.469'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252.445', 'D08.811.277.656.300.480.525.700.350', '... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Binocular coordination during reading of blurred and nonblurred text. | PURPOSE: Reading a text requires vergence angle adjustments, so that the images in the two eyes fall on corresponding retinal areas. Vergence adjustments bring the two retinal images into Panum's fusional area and therefore, small remaining errors or regulations do not lead to double vision. The present study evaluated... | ['Accommodation, Ocular', 'Adolescent', 'Adult', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Reading', 'Saccades', 'Vision Disparity', 'Vision, Binocular', 'Visual Perception', 'Young Adult'] | 22,058,330 | [['G14.010'], ['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.423.557'], ['G14.350.500'], ['F02.463.593.778.255.780', 'F02.463.593.932.877', 'G14.930'], ['F02.463.593.932.885'], ['F02.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Hemostatic disorders with secretolytics? A contribution to drug safety]. | Based on literature and on the results of this open clinical trial we conclude, that there is no connection between application of the above named group of drugs and the change in parameters of haemostasis function, which might lead to a manifest haemorrhagic diathesis. Within the period surveyed of 14 days no case of ... | ['Ambroxol', 'Blood Coagulation', 'Bromhexine', 'Drug Combinations', 'Hemorrhagic Disorders', 'Humans', 'Oxytetracycline', 'Thrombocytopenia'] | 1,002,355 | [['D02.092.146.300.100', 'D02.092.384.175.100'], ['G09.188.390.150'], ['D02.092.146.300', 'D02.092.384.175'], ['D26.310'], ['C15.378.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.847.562.900.600', 'D04.615.562.900.600'], ['C15.378.140.855']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of environmental toxins on lymphocyte function: studies in rhesus and man. | The immune system is a potential target of environmental toxins. Impairment of immune function could have a disastrous effect upon the affected individual. We had the unique opportunity to study the results of a prolonged exposure to TCDD (2,3,7,8-tetrachlorodibenzo-P-dioxin) in rhesus monkeys and their offspring. Subs... | ['Adult', 'Aged', 'Aldicarb', 'Animals', 'Environmental Pollutants', 'Female', 'Humans', 'Immunoglobulins', 'Lymphocyte Subsets', 'Lymphocytes', 'Macaca mulatta', 'Middle Aged', 'Polychlorinated Dibenzodioxins'] | 2,048,762 | [['M01.060.116'], ['M01.060.116.100'], ['D02.241.081.251.046'], ['B01.050'], ['D27.888.284'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['A11.118.637.555.567.550', 'A15.145.229.637.555.567.550', 'A15.382.490.555.567.550'], ['A11.118.637.555.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Action of ammonium meta vanadate on hepatic enzymes in vitro. | In an in vitro study with rat liver, ammonium meta vanadate (NH4VO3) was found to inhibit microsomal ketamine N-demethylation, lipid peroxidation, and hydrogen peroxide formation; to have no effects on 4-methylaminoantipyrine N-demethylation and on glucuronyltransferase I activity, and to enhance glucuronyltransferase ... | ['Animals', 'Cytosol', 'In Vitro Techniques', 'Liver', 'Microsomes, Liver', 'Mitochondria, Liver', 'Rats', 'Vanadium'] | 6,605,135 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['E05.481'], ['A03.620'], ['A11.284.835.540.541'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.268.556.920', 'D01.268.956.886', 'D01.552.544.920']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Equity in access to public dental services: the experience from Norway. | The aim of this study was to identify possible factors associated with the marked geographical variation in supply of public dental services in Norway. We identified three sources for this uneven distribution: differences in dental care needs, differences in revenue levels between counties, and differences in the party... | ['Adolescent', 'Child', 'Child, Preschool', 'Dental Health Services', 'Dentists', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Humans', 'Income', 'Infant', 'Local Government', 'Norway', 'Politics', 'Public Health Dentistry', 'Regression Analysis', 'Small-Area Analysis', 'Workforce'] | 11,831,487 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['N02.421.240'], ['M01.526.485.330', 'N02.360.330'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['M01.060.703'], ['I01.409.700', 'N03.540.348.750'], ['Z01.542.816.374'],... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
COVID-19: Initial Perioperative and Perianesthesia Nursing Response in a Military Medical Center. | Nurses have historically led efforts to improve the health of populations while simultaneously and unselfishly providing care during pivotal moments of national need. The COVID-19 pandemic has placed an unprecedented strain on the US health care system, including severe shortages of hospital beds, supplies, equipment, ... | ['COVID-19', 'Clinical Competence', 'Coronavirus Infections', 'Hospitals, Military', 'Humans', "Nurse's Role", 'Pandemics', 'Perioperative Nursing', 'Pneumonia, Viral', 'United States'] | 32,561,253 | [['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['C01.925.782.600.550.200'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.... | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Costs and outcomes of total hip and knee joint replacement for rheumatoid arthritis. | The objective of the study was to ascertain costs and outcomes of total joint replacement surgery for rheumatoid arthritis (RA) in Australia from the patients' perspective and to explore whether costs were affected by health status pre- or postsurgery. RA patients, scheduled for primary unilateral total knee replacemen... | ['Aged', 'Arthritis, Rheumatoid', 'Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Australia', 'Female', 'Health Expenditures', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Quality of Life', 'Treatment Outcome'] | 18,500,442 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['Z01.639.100', 'Z01.678.100.373'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Antibody to staphylococcal enterotoxin A-induced human immune interferon (IFN gamma). | Antiserum to human gamma interferon (IFN gamma) was produced in rabbits immunized with partially purified (10(4.8) to 10(6.2) antiviral U/mg protein) staphylococcal enterotoxin A-induced IFN gamma. Staphylococcal enterotoxins, phytohemagglutinin M, concanavalin A, and pokeweed mitogen-induced antiviral activity in huma... | ['Animals', 'Antibodies, Viral', 'Antibody Formation', 'Antibody Specificity', 'Enterotoxins', 'Humans', 'Immune Sera', 'Immunity, Cellular', 'Interferons', 'Killer Cells, Natural', 'Rabbits', 'Staphylococcus'] | 6,162,895 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G12.450.050.370.250'], ['G12.100'], ['D23.946.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bypass surgery for complex middle cerebral artery aneurysms: impact of the exact location in the MCA tree. | OBJECT: The object of this study was to describe the authors' institutional experience in the treatment of complex middle cerebral artery (MCA) aneurysms necessitating bypass and vessel sacrifice.METHODS: Cases in which patients with MCA aneurysms were treated with a combination of bypass and parent artery sacrifice we... | ['Adolescent', 'Adult', 'Aged', 'Anesthesia', 'Central Nervous System Vascular Malformations', 'Cerebral Angiography', 'Cerebrovascular Circulation', 'Child', 'Embolization, Therapeutic', 'Female', 'Glasgow Outcome Scale', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Middle Cerebral Artery', 'Neurosurgica... | 24,286,147 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E03.155'], ['C10.500.190', 'C14.240.850.875', 'C16.131.240.850.875', 'C16.131.666.190'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['G09.330.100.159'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Apoptosis-like death was involved in freeze-drying-preserved fungus Mucor rouxii and can be inhibited by L-proline. | UNLABELLED: Freeze-drying is one of the most effective methods to preserve fungi for an extended period. However, it is associated with a loss of viability and shortened storage time in some fungi. This study evaluated the stresses that led to the death of freeze-dried Mucor rouxii by using cell apoptotic methods. The ... | ['Apoptosis', 'Caspases', 'Cell Nucleus', 'Cell Survival', 'Freeze Drying', 'Mucor', 'Proline', 'Reactive Oxygen Species'] | 26,681,175 | [['G04.146.954.035'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.346'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Construction and molecular dynamics simulation of calmodulin in the extended and in a bent conformation. | Analysis of sequence similarity and comparison of the three-dimensional (3D) structures of troponin C and calmodulin have revealed a sequence in the central helix of calmodulin with a high probability for bending. The three amino acids known to form a bend in the N-terminal portion of troponin C are also found in the c... | ['Calcium', 'Calmodulin', 'Cations', 'Protein Conformation', 'X-Ray Diffraction'] | 1,541,304 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D01.248.497.300'], ['G02.111.570.820.709'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of pomegranate peel extract on the oxidative stability of pomegranate seed oil. | Pomegranate seed oil is valuable source of bioactive compounds with health-beneficial effects, but it is sensitive to oxidation due to high content of PUFA. In order to improve stability of pomegranate seed oil, the influence of natural antioxidant (0.1% pomegranate peel extract) and a combination of synthetic antioxid... | ['Antioxidants', 'Butylated Hydroxytoluene', 'Fruit', 'Oxidation-Reduction', 'Phenols', 'Plant Extracts', 'Plant Oils', 'Pomegranate', 'Thiobarbituric Acid Reactive Substances'] | 32,682,230 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.657.239.216'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G02.700', 'G03.295.531'], ['D02.455.426.559.389.657'], ['D20.215.784.500', 'D26.667'], ['D10.627.700', 'D20.215.784.750'], ['B01.650.940.800.575.912.250.859.833.500.6... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Options to meet the future global demand of radionuclides for radionuclide therapy. | Nuclear medicine continues to represent one of the important modalities for cancer management. While diagnostic nuclear medicine for cancer management is fairly well established, therapeutic strategies using radionuclides are yet to be utilized to their full potential. Even if 1% of the patients undergoing diagnostic n... | ['Beta Particles', 'Gamma Rays', 'Half-Life', 'Humans', 'Internationality', 'Radioisotopes', 'Radiotherapy'] | 23,116,551 | [['G01.750.750.125'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615'], ['D01.496.749'], ['E02.815']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
RAB2A: a major subacrosomal protein of bovine spermatozoa implicated in acrosomal biogenesis. | The perinuclear theca (PT) of mammalian sperm is a unique subcellular structure encapsulating the nucleus. Compositionally, the PT is made up of at least six prominent polypeptides (60, 36, 31, 28, 24, and 15 kDa), of which only two have been sequence identified, as well as many less prominent ones. As an ongoing proce... | ['Acrosome', 'Algorithms', 'Amino Acid Sequence', 'Animals', 'Cattle', 'Golgi Apparatus', 'Humans', 'Male', 'Models, Biological', 'Molecular Sequence Data', 'Nuclear Envelope', 'Protein Isoforms', 'Sequence Homology, Amino Acid', 'Spermatozoa', 'Transport Vesicles', 'rab2 GTP-Binding Protein'] | 18,401,013 | [['A05.360.490.890.820.100', 'A11.284.430.214.190.875.190.550.040', 'A11.497.760.400.100'], ['G17.035', 'L01.224.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['L... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Unicompartmental Knee Arthroplasty Provides Higher Activity and Durability Than Valgus-Producing Proximal Tibial Osteotomy at 5 to 7 Years. | BACKGROUND: The cases of patients with medial compartment osteoarthritis who were ?55 years old and had a proximal tibial osteotomy (PTO) or medial unicompartmental knee arthroplasty (UKA) were compared. Outcomes included postoperative activity level, function, and survivorship free of revision to total knee arthroplas... | ['Adolescent', 'Adult', 'Arthroplasty, Replacement, Knee', 'Female', 'Humans', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Osteotomy', 'Prosthesis Failure', 'Range of Motion, Articular', 'Reoperation', 'Tibia', 'Treatment Outcome', 'Young Adult'] | 28,099,301 | [['M01.060.057'], ['M01.060.116'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400.410'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E04.555.580'], ['C23.550.767.865', 'E05.325.771'], ['E01.370.600.700', 'G11.427.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Augmentation or inhibition of IFN-gamma-induced MHC class II expression by lipopolysaccharides. The roles of TNF-alpha and nitric oxide, and the importance of the sequence of signaling. | MHC class II expression on macrophages is one determinant of Ag presentation and the vigor of CD4+ T cell immunity. We show that LPS may either inhibit or augment IFN-gamma-induced MHC class II on macrophages depending on the sequence of the IFN-gamma and LPS signals. LPS inhibited MHC class II when added simultaneousl... | ['Animals', 'Cells, Cultured', 'Drug Synergism', 'Female', 'Histocompatibility Antigens Class II', 'Interferon-gamma', 'Lipopolysaccharides', 'Macrophages', 'Mice', 'Mice, Inbred C3H', 'Nitric Oxide', 'RNA Processing, Post-Transcriptional', 'Signal Transduction', 'Time Factors', 'Tumor Necrosis Factor-alpha'] | 7,499,872 | [['B01.050'], ['A11.251'], ['G07.690.773.968.477'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['D09.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Parallelism between male mating propensity and chromosome arrangement frequency in natural populations of Drosophila ananassae. | Mating ability of different karyotypes due to sub-terminal (alpha or In(2L)A) inversion in 2L from two natural populations of Drosophila ananassae was investigated. The results show that the average number of females inseminated by a single male in 12-hour period varies for different karyotypes in males. The analysis o... | ['Animals', 'Chromosomes', 'Drosophila', 'Female', 'Genetics, Population', 'Male', 'Polymorphism, Genetic'] | 3,366,629 | [['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['H01.158.273.343.335'], ['G05.365.795']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Expansion of human embryonic stem cells in defined serum-free medium devoid of animal-derived products. | Human embryonic stem cells (hESCs) can serve as an unlimited cell source for cellular transplantation and tissue engineering due to their prolonged proliferation capacity and their unique ability to differentiate into derivatives of all three-germ layers. In order to reliably and safely produce hESCs, use of reagents t... | ['Animals', 'Cell Culture Techniques', 'Cell Differentiation', 'Cells, Cultured', 'Culture Media, Conditioned', 'Culture Media, Serum-Free', 'Dose-Response Relationship, Drug', 'Embryo, Mammalian', 'Fibroblast Growth Factors', 'Growth Substances', 'Humans', 'Laminin', 'Recombinant Proteins', 'Stem Cells'] | 15,971,228 | [['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['D27.720.470.305.255', 'E07.206.255'], ['G07.690.773.875', 'G07.690.936.500'], ['A16.254'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['D27.505.696.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensibility following innervated free TRAM flap for breast reconstruction: Part II. Innervation improves patient-rated quality of life. | BACKGROUND: Restoring sensory innervation may be a useful adjunct in free flap head and neck reconstruction but, as yet, has not been shown to improve outcomes of breast reconstruction. The authors' previous study demonstrated objectively improved sensation in a group of innervated transverse rectus abdominis musculocu... | ['Adult', 'Aged', 'Body Image', 'Breast Neoplasms', 'Confounding Factors, Epidemiologic', 'Female', 'Humans', 'Mammaplasty', 'Mastectomy, Modified Radical', 'Microsurgery', 'Middle Aged', 'Nerve Transfer', 'Patient Satisfaction', 'Prospective Studies', 'Quality of Life', 'Rectus Abdominis', 'Surgical Flaps', 'Surveys a... | 20,009,826 | [['M01.060.116'], ['M01.060.116.100'], ['F01.752.747.792.110', 'F02.463.593.112'], ['C04.588.180', 'C17.800.090.500'], ['N05.715.350.240', 'N06.850.490.718'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['E04.466.678.476'], ['E04.494', 'E05.591.580'], ['M01.060.116.630'], ['E04.525.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm. | During organogenesis, Sonic hedgehog (Shh) possesses dual functions: Shh emanating from midline structures regulates the positioning of bilateral structures at early stages, whereas organ-specific Shh locally regulates organ morphogenesis at later stages. The mesonephros is a transient embryonic kidney in amniote, wher... | ['Animals', 'Cell Differentiation', 'Cell Lineage', 'Crosses, Genetic', 'Female', 'Forkhead Transcription Factors', 'Gene Expression Regulation, Developmental', 'Hedgehog Proteins', 'In Situ Hybridization', 'Kidney', 'Male', 'Mesoderm', 'Mesonephros', 'Mice', 'Mice, Inbred ICR', 'Mice, Knockout', 'Notochord'] | 24,370,450 | [['B01.050'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['E05.393.281'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.308.310'], ['D12.644.276.671', 'D12.776.467.671', 'D23.529.671'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Integrated microelectrode array and microfluidics for temperature clamp of sensory neurons in culture. | A device for cell culture is presented that combines MEMS technology and liquid-phase photolithography to create a microfluidic chip that influences and records electrical cellular activity. A photopolymer channel network is formed on top of a multichannel microelectrode array. Preliminary results indicated successful ... | ['Action Potentials', 'Animals', 'Equipment Design', 'Ganglia, Spinal', 'Microelectrodes', 'Microfluidic Analytical Techniques', 'Neurons, Afferent', 'Patch-Clamp Techniques', 'Temperature'] | 15,616,746 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E05.320'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['E07.305.250.500'], ['E05.588.465'], ['A08.675.650', 'A11.671.650'], ['E05.200.500.905', 'E05.242.800'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710',... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolation of the volatile oil from Satureja thymbra by supercritical carbon dioxide extraction: chemical composition and biological activity. | Satureja thymbra L. is well known in Italy by the popular name of "Santoreggia sarda". It grows only in Sardinia and nowadays it is restricted to the slope of the Colle San Michele in Cagliari. The composition of the aromatic extracts obtained by supercritical CO2 and by hydrodistillation and their antifungal activity ... | ['Carbon Dioxide', 'Chromatography, Supercritical Fluid', 'Oils, Volatile', 'Plant Oils', 'Satureja'] | 22,164,799 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.196.181.750'], ['D10.627.675'], ['D10.627.700', 'D20.215.784.750'], ['B01.650.940.800.575.912.250.583.520.935']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epidural infection associated with epidural catheterization in a cancer patient with back pain: case report. | Single epidural injections of local anaesthetic/steroid mixtures and epidural catheterization are useful in controlling pain when other measures fail. However, epidural infection is a recognized risk of these procedures, but can be difficult to diagnose. This case report illustrates the complexity of diagnosis and mana... | ['Analgesia, Epidural', 'Back Pain', 'Cross Infection', 'Epidural Space', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Sacrum', 'Spinal Neoplasms', 'Staphylococcal Infections'] | 7,952,374 | [['E03.091.080'], ['C23.888.592.612.107'], ['C01.248', 'C23.550.291.875.500'], ['A02.835.232.834.803.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['A02... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hybrid Magnetic-DNA Directed Immobilisation Approach for Efficient Protein Capture and Detection on Microfluidic Platforms. | In this study, a hybrid magnetic-DNA directed immobilisation approach is presented to enhance protein capture and detection on a microfluidic platform. DNA-modified magnetic nanoparticles are added in a solution to capture fluorescently labelled immunocomplexes to be detected optically. A magnetic set-up composed of cu... | ['Animals', 'DNA', 'Finite Element Analysis', 'Magnetic Phenomena', 'Mice', 'Microfluidic Analytical Techniques', 'Nanoparticles', 'Proteins'] | 28,298,637 | [['B01.050'], ['D13.444.308'], ['E05.355'], ['G01.358'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.588.465'], ['J01.637.512.600'], ['D12.776']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
If you hold it off-hours, will they come? Results from a feasibility project intended to stimulate interest in the physician-investigator career path among medical oncology trainees. | BACKGROUND: An "endangered species," the physician-scientist faces challenges in oncology. The authors thus implemented a series of voluntary off-hours sessions on academic development for their trainees.METHODS: Numerous workday interruptions among trainees led the authors to conclude that off-hours sessions would be ... | ['Biomedical Research', 'Career Choice', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Medical Oncology', 'Physicians', 'Pilot Projects', 'Research Personnel'] | 19,526,407 | [['H01.770.644.145'], ['F02.463.785.373.346.400'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['M01.526.485.810', 'N02.360.810'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'],... | ['Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Changes in the circadian rhythm of urinary cyclic adenosine monophosphate during the alcoholic withdrawal syndrome and related neurobiological correlations]. | Urinary cyclic adenosine monophosphate (AMP-c) was measured morning and evening in 35 patients with alcohol withdrawal syndrome (AWS). 65% of the patients revealed a higher night time than day time concentration of AMP-c in the urine, reflecting increased sympathetic adrenergic activity. The circadian rhythm was lost i... | ['Adult', 'Alcoholism', 'Circadian Rhythm', 'Clonidine', 'Cyclic AMP', 'Female', 'Humans', 'Piracetam', 'Sleep Initiation and Maintenance Disorders', 'Sleep, REM', 'Substance Withdrawal Syndrome', 'Tiapamil Hydrochloride'] | 2,993,962 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['G07.180.562.190'], ['D03.383.129.308.436.500'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.064.650', 'D02.241.081.018.110.650', 'D03.383.773.812.5... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of L-threonine dehydrogenase in somatic cell reprogramming. | Increasing evidence suggests that metabolic remodeling plays an important role in the regulation of somatic cell reprogramming. Threonine catabolism mediated by L-threonine dehydrogenase (TDH) has been recognized as a specific metabolic trait of mouse embryonic stem cells. However, it remains unknown whether TDH-mediat... | ['Alcohol Oxidoreductases', 'Animals', 'Arginine', 'Cell Differentiation', 'Cellular Reprogramming', 'Gene Expression Regulation, Developmental', 'Induced Pluripotent Stem Cells', 'Methylation', 'Mice', 'MicroRNAs', 'Protein Methyltransferases', 'Protein-Arginine N-Methyltransferases', 'RNA Interference', 'Stem Cells',... | 23,355,387 | [['D08.811.682.047'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G04.152'], ['G04.152.262', 'G05.135'], ['G05.308.310'], ['A11.872.040.500', 'A11.872.700.500'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.150.650.319', 'D13.444... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Macrophage-adipocyte interaction: marked interleukin-6 production by lipopolysaccharide. | OBJECTIVE: Recent studies suggested macrophages were integrated in adipose tissues, interacting with adipocytes, thereby exacerbating inflammatory responses. Persistent low-grade infection by gram-negative bacteria appears to promote atherogenesis. We hypothesized a ligand for toll-like receptor 4 (TLR4), bacterial lip... | ['3T3-L1 Cells', 'Adipocytes', 'Animals', 'Cell Communication', 'Cell Line', 'Cells, Cultured', 'Coculture Techniques', 'Drug Synergism', 'Interleukin-6', 'Lipopolysaccharides', 'Macrophages', 'Mice', 'Toll-Like Receptor 4', 'Tumor Necrosis Factor-alpha'] | 18,070,744 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['B01.050'], ['G04.085'], ['A11.251.210'], ['A11.251'], ['E05.481.500.374'], ['G07.690.773.968.477'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.52... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system. | BACKGROUND: Type III secretion systems (TTSS) are employed by numerous pathogenic and symbiotic bacteria to inject a cocktail of different "effector proteins" into host cells. These effectors subvert host cell signaling to establish symbiosis or disease.METHODOLOGY/PRINCIPAL FINDINGS: We have studied the injection of S... | ['Bacterial Proteins', 'Computer Simulation', 'Microscopy, Fluorescence', 'Protein Transport', 'Salmonella typhimurium'] | 18,478,101 | [['D12.776.097'], ['L01.224.160'], ['E01.370.350.515.458', 'E05.595.458'], ['G03.143.700'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Adding conversational interviews to a patient simulator. | In order to model motivational interviewing in a simulated case of alcohol abuse, a system of creating conversations was added to a computerized patient simulator. | ['Alcoholism', 'Communication', 'Counseling', 'Humans', 'Interviews as Topic', 'Kentucky', 'Medical History Taking', 'Motivation', 'Patients', 'Therapy, Computer-Assisted'] | 18,998,816 | [['C25.775.100.250', 'F03.900.100.350'], ['F01.145.209', 'L01.143'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.107.567.875.075.400', 'Z01.107.567.875.5... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Thyroid activity of spontaneous hypertensive rats. | Thyroid activity of both male and female spontaneous hypertensive (SH) rats was studied by measurements of uptake and rate of release of 131-I, urinary excretion of 131-I, and thyroxine secretion rate (TSR). In addition, thyroid glands were removed at death and weighed. Radioactivity of the thyroid gland of male rats m... | ['Animals', 'Body Weight', 'Chick Embryo', 'Female', 'Hypertension', 'Injections, Intraperitoneal', 'Iodine', 'Iodine Radioisotopes', 'Male', 'Methimazole', 'Organ Size', 'Rats', 'Thyroid Gland', 'Thyroxine', 'Time Factors'] | 1,144,416 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A13.350.150', 'A16.331.200'], ['C14.907.489'], ['E02.319.267.530.490'], ['D01.268.380.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D02.886.489.600', 'D03.38... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of fibular osteotomy in rotational osteotomy of the distal tibia. | A randomized prospective study was undertaken to assess the role of fibular osteotomy in distal tibial derotational osteotomies. Thirty-five patients were randomized to "intact fibula" and "osteotomized fibula" groups. There were no statistically significant differences in the amount of intraoperative derotation, time ... | ['Adolescent', 'Bone Diseases, Developmental', 'Child', 'Child, Preschool', 'Fibula', 'Humans', 'Infant', 'Osteotomy', 'Postoperative Complications', 'Postoperative Period', 'Prospective Studies', 'Tibia', 'Weight-Bearing', 'Wound Healing'] | 7,962,503 | [['M01.060.057'], ['C05.116.099'], ['M01.060.406'], ['M01.060.406.448'], ['A02.835.232.043.650.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04.555.580'], ['C23.550.767'], ['E04.614.750', 'N02.421.585.753.750'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.50... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The collection of general practice data for psychiatric service contracts. | A three-month prospective collection of primary care data from general surgery attendances in an inner London Health District was carried out to inform the setting of contracts for psychiatric services. This involved 21 general practitioners (GPs) selected from a total of 102 in the District. Information was collected ... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Contract Services', 'Data Collection', 'Family Practice', 'Female', 'Humans', 'Infant', 'London', 'Male', 'Mental Disorders', 'Mental Health Services', 'Middle Aged', 'Prospective Studies', 'Referral and Consultation'] | 8,037,958 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.463.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.433.553', 'Z01.542.363.300.553'], ['F03'],... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Lipid--lipoprotein composition in hypercholesterolemic children and their parents. | In 13 hypercholesterolemic children, re-screened for serum cholesterol after a 1-year interval, hypercholesterolemia was confirmed in only 61.5% of the cases. A tentative explanation seems to be the statistical principle of regression towards the mean. The lipid--lipoprotein analysis showed that serum and LDL cholester... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Cholesterol', 'Female', 'Humans', 'Hypercholesterolemia', 'Lipoproteins', 'Lipoproteins, HDL', 'Lipoproteins, LDL', 'Lipoproteins, VLDL', 'Male', 'Middle Aged', 'Phenotype', 'Triglycerides'] | 222,302 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Theory for the feedback inhibition of fast release of neurotransmitter. | Autoinhibition of neurotransmitter release occurs via binding of transmitter to appropriate receptors. Experiments have provided evidence suggesting that the control of neurotransmitter release in fast systems is mediated by these inhibitory autoreceptors. Earlier, the authors formulated and analysed a mathematical mod... | ['Acetylcholine', 'Acetylcholinesterase', 'Animals', 'Autoreceptors', 'Binding Sites', 'Computer Simulation', 'Excitatory Amino Acid Agonists', 'Feedback', 'Glutamic Acid', 'Humans', 'Membrane Potentials', 'Models, Biological', 'Muscarine', 'Muscarinic Antagonists', 'N-Methylaspartate', 'Neurotransmitter Agents', 'Seco... | 10,938,630 | [['D02.092.211.111'], ['D08.811.277.352.100.170.176'], ['B01.050'], ['D12.776.543.750.035', 'D12.776.543.750.720.670.100'], ['G02.111.570.120'], ['L01.224.160'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['L01.906.394.211'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells. | We used a combined biochemical, pharmacological, and electrophysiological approach to study the effects of hyposmotic swelling on organic osmolyte efflux in endothelial cells (EC). In [3H]taurine-loaded monolayers of calf pulmonary artery EC (CPAEC), hyposmolality activated time- and dose-dependent effluxes of [3H]taur... | ["4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid", 'Acetophenones', 'Amino Acids', 'Animals', 'Cattle', 'Cells, Cultured', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'Hypotonic Solutions', 'Ion Channels', 'Kinetics', 'Niflumic Acid', 'Nitrobenzoates', 'Phospholipases A', 'Phospholipases A2', 'Pulmonary Artery', 'Q... | 9,252,459 | [['D02.455.426.559.389.150.700.200', 'D02.500.375.125', 'D02.886.250.125'], ['D02.522.120'], ['D12.125'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.389'], ['D26.776.399'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imaging of Kingella kingae musculoskeletal infections in children: a series of 5 cases. | PURPOSE: Kingella kingae musculoskeletal infections continue to be under-diagnosed and there remains a paucity of literature on its imaging features. The purpose of this manuscript is to review the imaging, clinical, and laboratory findings of microbiology-proven K. kingae infections.MATERIALS AND METHODS: A retrospect... | ['Arthritis, Infectious', 'Child, Preschool', 'Diagnosis, Differential', 'Discitis', 'Female', 'Humans', 'Infant', 'Kingella kingae', 'Male', 'Myositis', 'Neisseriaceae Infections', 'Osteomyelitis', 'Retrospective Studies'] | 29,909,593 | [['C01.100', 'C05.550.114.099'], ['M01.060.406.448'], ['E01.171'], ['C01.160.762.301', 'C05.116.165.762.301', 'C05.116.900.853.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['B03.440.400.425.550.400.375', 'B03.660.075.525.410.410'], ['C05.651.594', 'C10.668.491.562'], ['C01.150.252.400.625'],... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc. | Thanatos-associated proteins (THAPs) are zinc-dependent, sequence-specific DNA-binding factors involved in cell proliferation, apoptosis, cell cycle, chromatin modification and transcriptional regulation. THAP11 is the most recently described member of this human protein family. In this study, we show that THAP11 is ub... | ['Animals', 'Cell Proliferation', 'DNA-Binding Proteins', 'Down-Regulation', 'Fibroblasts', 'Humans', 'Mice', 'Mice, Knockout', 'Nerve Tissue Proteins', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins c-myc', 'RNA Interference', 'Repressor Proteins', 'Transcription, Genetic', 'Tumor Cells, Cultured'] | 19,008,924 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.260'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic respiratory illnesses in Jordan: pulmonary physicians' experiences in risk reduction. | Chronic respiratory diseases are on the rise in Jordan. However, there is limited research on the symptoms reported by patients, the triggers associated with their illnesses, and the health education efforts of pulmonary physicians. Thus, the purpose of this qualitative study was to understand these issues from physici... | ['Adult', 'Asthma', 'Chest Pain', 'Dyspnea', 'Health Promotion', 'Humans', 'Interviews as Topic', 'Jordan', 'Male', 'Middle Aged', 'Needs Assessment', 'Patient Education as Topic', 'Physicians', 'Prevalence', 'Pulmonary Disease, Chronic Obstructive', 'Smoking', 'Tuberculosis, Pulmonary'] | 20,570,802 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C23.888.592.612.233'], ['C08.618.326', 'C23.888.852.371'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The effect of social support and physical touch on cardiovascular reactions to mental stress. | To examine the effects of social support on cardiovascular reactions to behavioral stress, the present study tested the relative contribution of three elements of social support: the presence of another person in the laboratory; the presence of a person considered to be a friend; and physical touch. Sixty undergraduate... | ['Adult', 'Arousal', 'Blood Pressure', 'Female', 'Heart Rate', 'Humans', 'Interpersonal Relations', 'Problem Solving', 'Psychomotor Performance', 'Self Concept', 'Social Environment', 'Social Support', 'Stress, Psychological', 'Touch'] | 1,593,512 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F01.752.747.792'], ['I01.880.85... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Growth differentiation factor 11 locally controls anterior-posterior patterning of the axial skeleton. | Growth and differentiation factor 11 (GDF11) is a transforming growth factor â family member that has been identified as the central player of anterior-posterior (A-P) axial skeletal patterning. Mice homozygous for Gdf11 deletion exhibit severe anterior homeotic transformations of the vertebrae and craniofacial defects... | ['Animals', 'Body Patterning', 'Bone Morphogenetic Proteins', 'Gene Expression Regulation, Developmental', 'Growth Differentiation Factors', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mosaicism', 'Osteogenesis', 'Signal Transduction', 'Spine'] | 31,183,862 | [['B01.050'], ['G07.345.500.100'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['G05.308.310'], ['D12.644.276.954.300', 'D12.776.467.942.300', 'D23.529.942.300'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome. | The complete nucleotide sequence of the mitochondrial genome of the domestic dog, Canis familiaris, was determined. The length of the sequence was 16,728 bp; however, the length was not absolute due to the variation (heteroplasmy) caused by differing numbers of the repetitive motif, 5'-GTACACGT(A/G)C-3', in the control... | ['Animals', 'Base Sequence', 'Cats', 'DNA, Mitochondrial', 'Dogs', 'Evolution, Molecular', 'Genome', 'Phylogeny', 'RNA, Ribosomal', 'RNA, Transfer', 'Sequence Homology, Nucleic Acid', 'Untranslated Regions'] | 9,878,232 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D13.444.308.283.225'], ['B01.050.150.900.649.313.750.250.216.200'], ['G05.045.250', 'G16.075.250'], ['G05.360.340'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686'], ['D13.444.735.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Influence of filtration on concentrations of 62 elements analysed on crystalline bedrock groundwater samples by ICP-MS. | Analyses of unfiltered and filtered (< 0.45 micron and < 0.10 micron) groundwater samples from 15 selected wells in crystalline bedrock aquifers of the Oslo area, Norway, have been studied for 62 chemical elements. While concentrations of almost all elements vary over several orders of magnitude between the individual ... | ['Filtration', 'Humans', 'Mass Spectrometry', 'Norway', 'Particle Size', 'Water Pollutants, Chemical', 'Water Purification', 'Water Supply'] | 10,507,155 | [['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['Z01.542.816.374'], ['G02.712'], ['D27.888.284.903.655'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900'], ['J01.293.821.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
A novel, conserved gene of the rat that is developmentally regulated in the testis. | From a rat testis library three overlapping cDNA clones were isolated that represent a novel single-copy gene, designated Tegt. Two transcripts of 2.8 and 1.0 kb were found in each organ tested. The shorter transcript was highly abundant in adult testis. A similar expression pattern was found in the mouse. Analysis of ... | ['Aging', 'Amino Acid Sequence', 'Animals', 'Apoptosis Regulatory Proteins', 'Base Sequence', 'Blotting, Southern', 'Cattle', 'Chickens', 'Chromosome Mapping', 'Conserved Sequence', 'Female', 'Gene Expression Regulation', 'Gene Library', 'Humans', 'Male', 'Membrane Proteins', 'Mice', 'Molecular Sequence Data', 'Organ S... | 8,012,111 | [['G07.345.124'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hemodialysis using a valveless pulsatile blood pump. | Research on pulsatile blood pumps for extracorporeal life support has been widely performed because of the proven advantageous effects of blood pulsation. However, studies on the use of pulsatile blood pumps for hemodialysis are limited, although available evidence demonstrates that pulsatile blood flow has a positive ... | ['Animals', 'Assisted Circulation', 'Blood Flow Velocity', 'Cattle', 'Dogs', 'Equipment Design', 'Kidney Failure, Chronic', 'Pulsatile Flow', 'Renal Dialysis'] | 18,356,654 | [['B01.050'], ['E04.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.320'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['G01.482.620', 'G09.330.380.630.555'], ['E02.870.300', 'E02.912.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonsurgical treatment of Brodie bite assisted by 3-dimensional planning and assessment. | This case report describes the nonsurgical treatment of an adolescent patient with a severe transverse discrepancy presented as a Brodie bite and retrognathic mandible. Distraction osteogenesis has been often used for similar cases in the literature. However, in this patient, a fixed appliance with 1 maxillary extracti... | ['Cephalometry', 'Child', 'Cone-Beam Computed Tomography', 'Dental Models', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Malocclusion, Angle Class II', 'Orthodontic Appliances, Functional', 'Radiography, Panoramic', 'Retrognathia', 'Tooth Extraction', 'Tooth, Supernumerary'] | 30,173,846 | [['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['C07.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
[Application of CiteSpace software in the visualization analysis of work-related musculoskeletal disorders]. | Objective: To investigate the visual application of the CiteSpace software in the field of work-related musculoskeletal disorders (WMSDs) . Methods: The literature on WMSDs research, published from 1991 to 2017, was retrieved in Web of Science database. The CiteSpace 5.2 was used to make visualization analysis on the h... | ['Diagnosis, Computer-Assisted', 'Humans', 'Musculoskeletal Diseases', 'Occupational Diseases', 'Software'] | 31,726,509 | [['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05'], ['C24'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The use of smartphones in radiographic diagnosis: accuracy on the detection of marginal gaps. | OBJECTIVE: To compare the accuracy of computer monitor and smartphone screen for radiographic diagnosis of marginal gap.MATERIALS AND METHODS: Forty teeth with mesial-occlusal-distal inlays (each tooth with a perfect fit and a 0.4-mm marginal gap restoration) were imaged with a phosphor plate system. Original digital r... | ['Humans', 'Inlays', 'Radiography, Dental', 'Sensitivity and Specificity', 'Smartphone', 'Tooth'] | 30,783,793 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.323.428.275', 'E06.780.346.737.500', 'E07.695.190.190.350'], ['E01.370.350.700.720', 'E06.342.764'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['L01.178.847.698.30... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Changes in the electrical activity of the medial septal region, piriform cortex and amygdala during epileptogenesis in the model of temporal lobe epilepsy]. | Local field potentials (EEGs) in the medial septal area, amygdala and piriform cortex were recorded in waking guinea pigs in the control and during epileptogenesis in the model of chronic temporal lobe epilepsy (lithium-pilocarpin model of status epilepticus). Analysis of changes in rhythmical activity and interstructu... | ['Amygdala', 'Animals', 'Disease Models, Animal', 'Electroencephalography', 'Epilepsy, Temporal Lobe', 'Female', 'Guinea Pigs', 'Lithium Chloride', 'Male', 'Pilocarpine', 'Septum of Brain', 'Status Epilepticus'] | 21,675,228 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['B01.050.150.900.649.313.992.550'], ['D01.210.450.150.450', 'D01.510.500'], ['D03.132.672'], ['A08.186... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Separate MRI quantification of dispersed (ferritin-like) and aggregated (hemosiderin-like) storage iron. | A new MRI method is proposed for separately quantifying the two principal forms of tissue storage (nonheme) iron: ferritin iron, a dispersed, soluble fraction that can be rapidly mobilized, and hemosiderin iron, an aggregated, insoluble fraction that serves as a long-term reserve. The method utilizes multiple spin echo... | ['Adolescent', 'Adult', 'Biomarkers', 'Female', 'Ferritins', 'Hemosiderin', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Liver', 'Magnetic Resonance Imaging', 'Male', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tissue Distribution', 'Young Adult', 'beta-Thalassemia'] | 20,432,291 | [['M01.060.057'], ['M01.060.116'], ['D23.101'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D12.776.556.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A03.620'], ['E01.370.350.825.500'], ['E05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Studies on fine structure and location of lipids in quick-freeze replicas of atherosclerotic aorta of WHHL rabbits. | The fine structure of intracellular and extracellular lipids in the atherosclerotic aorta of Watanabe-heritable hyperlipidemic (WHHL) rabbits was demonstrated by a quick-freeze etching technique. Many lipid droplets, with and without a membrane, were observed in the foam cells. Membrane-free droplets were observed as o... | ['Animals', 'Aorta, Thoracic', 'Aortic Diseases', 'Arteriosclerosis', 'Extracellular Matrix', 'Extracellular Space', 'Foam Cells', 'Freeze Etching', 'Lipids', 'Male', 'Microscopy, Electron', 'Microscopy, Electron, Scanning', 'Rabbits'] | 3,099,465 | [['B01.050'], ['A07.015.114.056.372'], ['C14.907.109'], ['C14.907.137.126'], ['A11.284.295.310'], ['A10.082.500', 'A11.284.295'], ['A11.329.372.368', 'A11.627.482.368', 'A11.733.397.368', 'A15.382.670.522.368', 'A15.382.680.397.368'], ['E01.370.225.500.620.620.260.400', 'E01.370.225.750.600.620.260.400', 'E05.200.500.6... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary influences in the preferences of pre-weanling Long-Evans rats for the anal excreta of adult males. | Male rats which ingest feces of lactating females produce anal excreta which is attractive to pups. This excreta is as attractive as that of lactating females and more attractive than the excreta of males eating a diet of lab chow only. Anal excreta of males which consume feces of lactating females is more attractive t... | ['Animals', 'Coprophagia', 'Diet', 'Feces', 'Female', 'Food Preferences', 'Humans', 'Lactation', 'Male', 'Odorants', 'Pregnancy', 'Rats', 'Rats, Inbred Strains'] | 6,685,320 | [['B01.050'], ['F01.145.113.547.500'], ['G07.203.650.240'], ['A12.459'], ['F01.145.407.516', 'G07.203.650.353.516'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.523', 'G08.686.702.500'], ['G16.500.275.640', 'N06.230.480'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.19... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sequence, organization, transcription and evolution of RNA polymerase subunit genes from the archaebacterial extreme halophiles Halobacterium halobium and Halococcus morrhuae. | The genes for the four largest subunits, A, B', B" and C, of the DNA-dependent RNA polymerase were cloned from the extreme halophile Halobacterium halobium and sequenced and their transcription was analyzed. The downstream half of this gene cluster from another extreme halophile Halococcus morrhuae was also cloned, seq... | ['Archaea', 'Bacteria', 'Base Sequence', 'Biological Evolution', 'Chromosome Mapping', 'Cloning, Molecular', 'DNA-Directed RNA Polymerases', 'Genes, Bacterial', 'Halobacterium', 'Molecular Sequence Data', 'Multigene Family', 'Transcription, Genetic'] | 2,495,365 | [['B02'], ['B03'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['E05.393.183'], ['E05.393.220'], ['D08.811.913.696.445.735.270'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B02.200.400.400.410'], ['L01.453.245.667'], ['G05.360.340.024.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Effectiveness of a patient-centered psychosomatic consultation service. Report of a catamnestic study]. | After a short review of the latest scientific publications on psychosomatic consultation activity the results of an empirical study of the consultant service in the Department of Psychotherapy and Psychosomatic Medicine at the Frankfurt University Medical Center are presented. Patient documentations and data from a ret... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Psychophysiologic Disorders', 'Psychotherapy', 'Referral and Consultation'] | 2,717,697 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.592.700'], ['F04.754'], ['N04.452.758.849']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets. | CONTEXT: Development of floating drug delivery systems (FDDS) is challenging. To facilitate this task, an evaluation method was proposed, which allows for a combined investigation of drug release and flotation.OBJECTIVE: It was the aim of the study to use functionalized calcium carbonate (FCC)-based lipophilic mini-tab... | ['Caffeine', 'Calcium Carbonate', 'Chemistry, Pharmaceutical', 'Computer Simulation', 'Delayed-Action Preparations', 'Drug Delivery Systems', 'Drug Liberation', 'Excipients', 'Gastric Mucosa', 'In Vitro Techniques', 'Solubility', 'Tablets', 'Technology, Pharmaceutical'] | 26,307,090 | [['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['H01.158.703.007', 'H01.181.466'], ['L01.224.160'], ['D26.255.210', 'E02.319.300.253'], ['E02.319.300'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['D26.650.700.419', 'D27.720.744.770.419'], ['A03.556.875.8... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Primordial germ cells in the dorsal mesentery of the chicken embryo demonstrate left-right asymmetry and polarized distribution of the EMA1 epitope. | Despite the importance of the chicken as a model system, our understanding of the development of chicken primordial germ cells (PGCs) is far from complete. Here we characterized the morphology of PGCs at different developmental stages, their migration pattern in the dorsal mesentery of the chicken embryo, and the distr... | ['Animals', 'Biomarkers', 'Cell Movement', 'Chick Embryo', 'Epitopes', 'Germ Cells', 'Mesentery'] | 24,697,411 | [['B01.050'], ['D23.101'], ['G04.198', 'G07.568.500.180'], ['A13.350.150', 'A16.331.200'], ['D23.050.550'], ['A05.360.490', 'A11.497'], ['A01.923.047.025.600.451']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Impact of the standardized uptake value on the body trunk with truncation error of ì-map in the positron emission tomography/computed tomography: phantom studies]. | PURPOSE: The aim of this study was evaluate to impact of standardized uptake value (SUV) on the body trunk with truncation error of ì-map for CT attenuation correction (CTAC) in whole-body 2-deoxy-2-[(18)F] fluoro-D-glucose ((18)F-FDG)-positron emission tomography (PET)/CT with use of anthropomorphic phantom.METHODS: W... | ['Humans', 'Multimodal Imaging', 'Neoplasms', 'Phantoms, Imaging', 'Positron-Emission Tomography', 'Tomography, X-Ray Computed'] | 23,448,836 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.567'], ['C04'], ['E07.671'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.825.800.399', 'E01.370.384.730.800.399'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrochemical biosensing of galactose based on carbon materials: graphene versus multi-walled carbon nanotubes. | In this study, two enzyme electrodes based on graphene (GR), Co3O4 nanoparticles and chitosan (CS) or multi-walled carbon nanotubes (MWCNTs), Co3O4 nanoparticles, and CS, were fabricated as novel biosensing platforms for galactose determination, and their performances were compared. Galactose oxidase (GaOx) was immobil... | ['Biosensing Techniques', 'Electrochemical Techniques', 'Electrodes', 'Enzymes, Immobilized', 'Galactose', 'Glucose Oxidase', 'Graphite', 'Humans', 'Limit of Detection', 'Nanotubes, Carbon'] | 27,074,783 | [['E05.601.043'], ['E05.301'], ['E07.305.250'], ['D08.811.180', 'D12.776.463.500'], ['D09.947.875.359.377'], ['D08.811.682.047.239'], ['D01.268.150.300', 'D01.578.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['D01.268.150.250.500'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Ultrastructure of spermiogenesis and the spermatozoon in Taenia crassiceps strobilae WFU strain (Cestoda, Cyclophyllidea, Taeniidae) from golden hamsters. | Strobilae from Taenia crassiceps (WFU strain) were obtained from outbred hamsters (Mesocricetus auratus) by feeding them viable metacestodes maintained by intraperitoneal passage in female Balb/c mice. Mature and gravid proglottids from strobilae were recovered from hamster intestines and fixed for light and electron m... | ['Animals', 'Animals, Outbred Strains', 'Cricetinae', 'Female', 'Male', 'Mesocricetus', 'Mice', 'Mice, Inbred BALB C', 'Spermatogenesis', 'Spermatozoa', 'Taenia'] | 15,146,328 | [['B01.050'], ['B01.050.050.284'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['G04.152.650.624', 'G08.686.784.310.760'], ['A05.360.490.890'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are there good ways to give 'bad news'? | There has been considerable speculation about the inevitability of parental dissatisfaction with being informed about their child's disability. Mothers and fathers of 24 infants with a recently diagnosed disability were interviewed regarding their preferences for how to be told the "bad news." Qualitative analyses reve... | ['Humans', 'Infant, Newborn', 'Parents', 'Physician-Patient Relations', 'Truth Disclosure'] | 8,441,562 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F01.829.401.046.800', 'I01.880.604.583.080.134.800']] | ['Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
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