Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Pregnancy imprints regulatory memory that sustains anergy to fetal antigen. | Pregnancy is an intricately orchestrated process where immune effector cells with fetal specificity are selectively silenced. This requires the sustained expansion of immune-suppressive maternal FOXP3(+) regulatory T cells (T(reg) cells), because even transient partial ablation triggers fetal-specific effector T-cell a... | ['Adoptive Transfer', 'Animals', 'Antigens', 'CD4-Positive T-Lymphocytes', 'Clonal Anergy', 'Female', 'Fetal Proteins', 'Fetus', 'Forkhead Transcription Factors', 'Immunologic Memory', 'Interferon-gamma', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Postpartum Period', 'Pregnancy', 'T-Lymphocytes, Regu... | 23,023,128 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['D23.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G12.535.425.100'], ['D12.776.320'], ['A16.378'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G12.450.050.500'], ['D12.644.276.374.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Centrioles and cilia in the mesothelial cells of the pericanalicular region. | An evaluation of 70 trabecular meshwork biopsies obtained at the time of therapeutic surgery in glaucomatous and cataractous eyes revealed that the mesothelial cells in the iridocorneal angle had a marked abundance of cilia and centrioles. The distribution of cells showing cilia and/or centrioles is positively correlat... | ['Biopsy', 'Cataract', 'Cilia', 'Connective Tissue', 'Connective Tissue Cells', 'Cornea', 'Eye', 'Glaucoma', 'Humans', 'Iris', 'Organoids'] | 931,695 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C11.510.245'], ['A11.284.180.165'], ['A10.165'], ['A11.329'], ['A09.371.060.217'], ['A01.456.505.420', 'A09.371'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Potential interventions for the prevention of childhood pneumonia: geographic and temporal differences in serotype and serogroup distribution of sterile site pneumococcal isolates from children--implications for vaccine strategies. | Streptococcus pneumoniae is a leading cause of fatal bacterial pneumonia in young children. Pneumococcal polysaccharide vaccines have not been promoted for use in young children because many constituent serotypes are not immunogenic in children < 2 years old. Conjugating pneumococcal polysaccharide epitopes to a protei... | ['Age Distribution', 'Bacterial Vaccines', 'Child, Preschool', 'Developing Countries', 'Europe', 'Humans', 'Pneumococcal Infections', 'Pneumonia, Bacterial', 'Prevalence', 'Seroepidemiologic Studies', 'Serotyping', 'Streptococcus pneumoniae', 'United States', 'Vaccination'] | 7,667,055 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['D20.215.894.135'], ['M01.060.406.448'], ['I01.615.500.300'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.890.670'], ['C01.150.252.620', 'C01.748.610.540', 'C08.381.677.540', 'C08.730.610.540'], ['E05.318.308.985.525.750', 'N01... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp). | Experimental biological model system outcomes such as altered animal movement capability or behaviour are difficult to quantify manually. Existing automatic movement tracking devices can be expensive and imposing upon the typical environment of the animal model. We have developed a novel multiplatform, free-to-use open... | ['Algorithms', 'Animals', 'Drosophila', 'Larva', 'Mice, Inbred C57BL', 'Video Recording'] | 31,451,798 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['L01.280.960']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence and risk factors of nonalcoholic fatty liver disease in breast cancer patients. | AIMS AND BACKGROUND: We aimed to evaluate the prevalence of nonalcoholic fatty liver disease (NAFLD) in breast cancer patients using liver magnetic resonance imaging (MRI), and to investigate factors associated with NAFLD.METHODS: We evaluated 104 patients surgically treated for breast cancer at our hospital between Se... | ['Alanine Transaminase', 'Aspartate Aminotransferases', 'Body Mass Index', 'Breast Neoplasms', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Hypertension', 'Liver', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Odds Ratio', 'Prevalence', 'Risk Factors'] | 27,647,227 | [['D08.811.913.477.700.100'], ['D08.811.913.477.700.225'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', 'C17.800.090.500'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['A03.620'], ['M01.060.11... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Normative study of the implicit causality of 100 interpersonal verbs in Spanish. | This study provides normative data on the implicit causality of interpersonal verbs in Spanish. Two experiments were carried out. In Experiment 1, ratings of the implicit causality of 100 verbs classified into four types (agent-patient, agent-evocator, stimulus-experiencer, and experiencer-stimulus) were examined. An o... | ['Adult', 'Female', 'Humans', 'Language', 'Linguistics', 'Male', 'Spain', 'Vocabulary'] | 18,697,672 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['L01.559.598'], ['Z01.542.846'], ['L01.559.598.901']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Adsorption and expression of penicillin G acylase immobilized onto methacrylate polymers generated with varying pore generating solvent volume. | Adsorption and expression of penicillin G acylase was studied on macroporous methacrylate polymer beads of differing pore volume, generated with kerosene. The absorption and expression of the penicillin G acylase was dependent on pore volume. Maximum expression of 57% of adsorbed enzyme was obtained on beads synthesize... | ['Enzymes, Immobilized', 'Escherichia coli', 'Kerosene', 'Penicillin Amidase', 'Polymethacrylic Acids', 'Porosity'] | 1,768,081 | [['D08.811.180', 'D12.776.463.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D20.345.630.600', 'N06.230.132.258.630.600'], ['D08.811.277.087.690'], ['D02.241.081.069.800', 'D05.750.716.822.111.650', 'D25.720.716.822.111.650', 'J01.637.051.720.716.822.111.650'], ['G01.374.710']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Identification of health damage due to alcohol abuse; importance of alterations in cardiac function and blood chemistries. | Like in any other disease, diagnosis of health damage caused by alcohol abuse can be established all the easier and sooner, the more results of medical examinations are taken into consideration simultaneously. Evidence is presented that a larger proportion (96.4%) of alcoholics suffer from compromised cardiac function ... | ['Adult', 'Alcoholism', 'Blood Chemical Analysis', 'Electrocardiography', 'Electrolytes', 'Female', 'Heart', 'Humans', 'Liver Function Tests', 'Male', 'Reference Values'] | 2,636,362 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E01.370.370.380.240', 'E01.370.405.240'], ['D01.248'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.372.460'], ['E05.978.810']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Indoor air pollution due to tobacco smoke under real conditions. Preliminary results. | A short review exploring the generation and composition of tobacco smoke is given. Experimental arrangements used to record sidestream smoke are critically discussed. Data from own experiments in a tobacco smoke polluted office room were presented and discussed. These data include nicotine, ammonia, formaldehyde, aceta... | ['Carbon Monoxide', 'Climate', 'Humans', 'Microclimate', 'Microscopy, Electron', 'Nitrogen Dioxide', 'Nitrous Oxide', 'Smoking', 'Tobacco Smoke Pollution'] | 3,836,513 | [['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['G16.500.275.071', 'N06.230.300.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.275.071.450', 'N06.230.300.100.250.450'], ['E01.370.350.515.402', 'E05.595.402'], ['D01.362.635.600', 'D01.625.550.525', 'D01.650.550.587.625'], ['D01.362.635.625', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Wrong-way swallowing as a possible cause of bronchitis in patients with gastroesophageal reflux disease. | A new theory was tested that swallowing the wrong way is the cause of the strong correlation between bronchial symptoms and gastroesophageal reflux disease (GERD). One hundred and nineteen patients who were operated on for hiatal hernia and GERD were compared with 89 patients treated with the proton pump inhibitor omep... | ['Bronchitis', 'Chronic Disease', 'Cough', 'Deglutition Disorders', 'Female', 'Gastroesophageal Reflux', 'Hernia, Hiatal', 'Humans', 'Male', 'Middle Aged', 'Omeprazole'] | 8,517,146 | [['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['C23.550.291.500'], ['C08.618.248', 'C23.888.852.293'], ['C06.405.117.119', 'C09.775.174'], ['C06.405.117.119.500.484'], ['C23.300.707.960.500.467'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.886.640.074.500', 'D03.383... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structural organization and regulation of the gene for the androgen-dependent glutathione peroxidase-like protein specific to the mouse epididymis. | Genomic clones containing the gene for the glutathione peroxidase-like androgen-regulated murine epididymal protein of 24 kilodaltons (arMEP24) were isolated. A 9-kilobase DNA fragment was sequenced and found to contain the entire coding region of the gene, which is divided into five exons. The exact sizes and boundari... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Chromosome Mapping', 'Consensus Sequence', 'Dihydrotestosterone', 'Epididymis', 'Gene Expression Regulation, Enzymologic', 'Genes', 'Glutathione Peroxidase', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Recombinant F... | 8,469,239 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['G02.111.570.580.175'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['A05.360.444.371'], ['G05.308.320'], ['G05.360.340.024.340'], ['D08.811.682.732.500'], ['B01.050.150.900... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The independence of medical ethics. | This paper discusses the relation between medical ethics and general moral theory, the argument being that medical ethics is best seen as independent from general moral theory. According to this independence thesis, here explicated in terms of what is called a disunitarian stance, the very idea of applied ethics, which... | ['Biomedical Research', 'Ethical Analysis', 'Ethical Theory', 'Ethics, Medical', 'Humans', 'Interdisciplinary Communication', 'Moral Obligations', 'Personal Autonomy', 'Philosophy, Medical', 'Physician-Patient Relations', 'Social Values'] | 29,770,916 | [['H01.770.644.145'], ['K01.752.566.479.113', 'N05.350.244'], ['K01.752.566.479.118', 'N05.350.256'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['F01.829.500.760.500', 'K01.752.566.869.500'], ['F02.600', 'I01.880.... | ['Disciplines and Occupations [H]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
A graph theoretical approach for predicting common RNA secondary structure motifs including pseudoknots in unaligned sequences. | MOTIVATION: RNA structure motifs contained in mRNAs have been found to play important roles in regulating gene expression. However, identification of novel RNA regulatory motifs using computational methods has not been widely explored. Effective tools for predicting novel RNA regulatory motifs based on genomic sequence... | ['Algorithms', 'Base Sequence', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'RNA', 'Regulatory Sequences, Ribonucleic Acid', 'Sequence Alignment', 'Sequence Analysis, RNA', 'Sequence Homology, Nucleic Acid'] | 14,962,926 | [['G17.035', 'L01.224.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735'], ['D13.444.735.790.878.942', 'G02.111.570.080.689.687', 'G05.360.080.689.687'], ['E05.393.751'], ['E05.393.760.710'], ['G02.111.810.550', 'G05.810.550']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Juxtatumoral perinephric fat analysis in clear cell renal cell carcinoma. | PURPOSE: The purpose of the study was to evaluate the feasibility of using contrast-enhanced computed tomography (CECT)-based texture analysis (CTTA) metrics to differentiate between juxtatumoral perinephric fat (JPF) surrounding low-grade (ISUP 1-2) versus high-grade (ISUP 3-4) clear cell renal cell carcinoma (ccRCC).... | ['Adipose Tissue', 'Carcinoma, Renal Cell', 'Contrast Media', 'Female', 'Humans', 'Iopamidol', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Nephrectomy', 'Radiographic Image Interpretation, Computer-Assisted', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 30,506,142 | [['A10.165.114'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.400.880.410', 'D02.455.426.559.389.127.375.... | ['Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Antibody epitope mapping of the gastric H+/K(+)-ATPase. | Several antibodies against the gastric H+/K(+)-ATPase were analysed for the topological and sequence location of their epitopes. Topological mapping was done by comparing indirect immunofluorescent staining in intact and permeabilised rat parietal cells. Epitope definition was by Western analysis of intact and of tryps... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Endopeptidases', 'Epitopes', 'Fluorescent Antibody Technique', 'Gastric Mucosa', 'H(+)-K(+)-Exchanging ATPase', 'Molecular Sequence Data', 'Parietal Cells, Gastric', 'Rabbits', 'Rats', 'Restriction Mapping', 'Swine', 'Trypsin'] | 7,686,397 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['D08.811.277.656.300'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo release and turnover of secreted platelet antiheparin proteins in rhesus monkey (Macaca mulatta). | Human and rhesus monkey platelets secrete at least two antiheparin proteins: platelet factor 4 (PF4) and low affinity platelet factor 4 (LA-PF4). Neither of these proteins showed species-related antigenic differences. As determined by radioimmunoassay, the levels of PF4 and LA-PF4 antigen per 10(9) monkey platelets amo... | ['Animals', 'Beta-Globulins', 'Blood Coagulation Factors', 'Epitopes', 'Epoprostenol', 'Half-Life', 'Heparin', 'Humans', 'Macaca', 'Macaca mulatta', 'Platelet Factor 4', 'Species Specificity', 'beta-Thromboglobulin'] | 6,158,350 | [['B01.050'], ['D12.776.124.790.223', 'D12.776.377.715.182'], ['D12.776.124.125', 'D23.119'], ['D23.050.550'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['G01.910.405'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Saccadic oscillations in 4 dogs and 1 cat. | Disorders affecting the control of saccadic eye movements result in involuntary saccadic oscillations and are widely reported in human medicine. Information regarding the occurrence and potential importance of saccadic oscillations in veterinary medicine is currently limited. The clinical histories of three dogs and on... | ['Animals', 'Cat Diseases', 'Cats', 'Dog Diseases', 'Dogs', 'Eye Movement Measurements', 'Female', 'Male', 'Neurologic Examination', 'Ocular Motility Disorders'] | 29,704,274 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.380.230', 'E01.370.405.245.787'], ['E01.370.376.550', 'E01.370.600.550'], ['C10.228.758', 'C10.292.562', 'C11.590']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Active Crohn's disease patients show a distinctive expansion of circulating memory CD4+CD45RO+CD28null T cells. | In a previous study we found an expansion of circulating memory (CD45RO(+)) CD4(+) T cells in patients with Crohn's disease (CD). The aim of this work was to investigate the phenotypic and functional characteristics of this T-cell subset in CD. We analyzed in peripheral blood CD4(+)CD45RO(+) T cells from CD patients th... | ['Adult', 'Apoptosis', 'CD28 Antigens', 'CD4-Positive T-Lymphocytes', 'Crohn Disease', 'Cytokines', 'Female', 'Humans', 'Immunologic Memory', 'Leukocyte Common Antigens', 'Male'] | 15,024,186 | [['M01.060.116'], ['G04.146.954.035'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pilot Study to Assess the Use of Ultrasound in Evaluating the Abnormal Pediatric Airway. | In this study, we sought to explore the feasibility of using ultrasonography to evaluate airway anomalies in awake children with previous airway reconstruction. For the month of December 2018, we reviewed the medical records of patients aged <18 years old with prior airway reconstruction who had an outpatient appointme... | ['Adolescent', 'Child', 'Child, Preschool', 'Feasibility Studies', 'Female', 'Glottis', 'Humans', 'Laryngostenosis', 'Male', 'Otorhinolaryngologic Surgical Procedures', 'Pilot Projects', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Trachea', 'Tracheal Stenosis', 'Ultrasonography'] | 32,204,669 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360.591', 'C09.400.591', 'C16.131.740.658'], ['E04.580'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Coronary angioplasty. Statewide experience in California. | BACKGROUND: This report describes the in-hospital experience with percutaneous transluminal coronary angioplasty (PTCA) for the state of California in 1989. Data are derived from the statewide hospital discharge abstracts.METHODS AND RESULTS: A total of 24,883 PTCAs were performed; most patients (70%) were men and most... | ['Adolescent', 'Adult', 'Aged', 'Angioplasty, Balloon, Coronary', 'California', 'Coronary Artery Bypass', 'Female', 'Heart Diseases', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Risk Factors'] | 8,252,686 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
An arabinogalactan from the skin of Opuntia ficus-indica prickly pear fruits. | The cold-water extract from the skin of Opuntia ficus-indica fruits was fractionated by anion-exchange chromatography. The major fraction, which was purified by size exclusion chromatography, consisted of a polysaccharide composed of galactose and arabinose residues in the ratio 6.3:3.3, with traces of rhamnose, xylose... | ['Arabinose', 'Carbohydrate Sequence', 'Chromatography, Ion Exchange', 'Galactans', 'Galactose', 'Glucose', 'Magnetic Resonance Spectroscopy', 'Methylation', 'Microscopy, Electron, Scanning', 'Molecular Sequence Data', 'Opuntia', 'Polysaccharides', 'Rhamnose', 'Uronic Acids', 'Xylose'] | 15,063,212 | [['D09.947.875.627.166'], ['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.181.400.383'], ['D09.698.360'], ['D09.947.875.359.377'], ['D09.947.875.359.448'], ['E05.196.867.519'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['L01.453.245.667'], ['B01.650.940... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Ovarian insufficiency and galactosemia ]. | A primitive gonadal failure was observed in 2, 20 and 18 years old galactosemic female patients. The conditions was clinically suspected because of primary amenorrhea in one case and delayed puberty, followed by spaniomenorrhea in the other case, and confirmed by very low plasma estradiol and very high plasma gonadotro... | ['Adolescent', 'Adult', 'Amenorrhea', 'Child', 'Child, Preschool', 'Estrogens', 'Female', 'Galactosemias', 'Gonadotropins, Pituitary', 'Humans', 'Hypogonadism', 'Infant'] | 7,125,830 | [['M01.060.057'], ['M01.060.116'], ['C23.550.568.500'], ['M01.060.406'], ['M01.060.406.448'], ['D27.505.696.399.472.277'], ['C10.228.140.163.100.320', 'C16.320.565.189.320', 'C16.320.565.202.355', 'C18.452.132.100.320', 'C18.452.648.189.320', 'C18.452.648.202.355'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nursing documentation: a valuable clinical activity. | Professional codes and guidelines in combination with organisational and institutional policies and procedures identify and benchmark the standards of good documentation practices within a health care context. The Nursing and Midwifery Board of Australia has adopted, as part of the regulatory framework for nursing and ... | ['Australia', 'Documentation', 'Humans', 'Nursing Process'] | 25,715,532 | [['Z01.639.100', 'Z01.678.100.373'], ['L01.453.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.508']] | ['Geographicals [Z]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
The utility of targeted perioperative transthoracic echocardiography in managing an adult patient with anomalous origin of the left coronary artery-pulmonary artery for noncardiac surgery. | Congenital coronary artery anomalies as a whole are uncommon. Abnormal origin of the left coronary artery from the pulmonary artery (ALCAPA) is probably the most common congenital coronary defect. An overwhelming majority of the patients with untreated ALCAPA do not survive to adulthood. As yet, there is no consensus o... | ['Analgesics, Opioid', 'Anesthesia', 'Angina, Unstable', 'Bland White Garland Syndrome', 'Breast Neoplasms', 'Coronary Vessel Anomalies', 'Echocardiography', 'Female', 'Fentanyl', 'Humans', 'Middle Aged', 'Pain, Postoperative', 'Perioperative Care', 'Pulmonary Artery'] | 28,701,611 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E03.155'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['C14.240.400.210.249', 'C14.240.850.984.500.500', 'C14.280.400.210.249', 'C14.907.933.110.500', 'C16... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fentanyl attenuates the hemodynamic response to endotracheal intubation more than the response to laryngoscopy. | UNLABELLED: We examined the effectiveness of avoiding laryngoscopy in reducing the hemodynamic responses to orotracheal intubation during the induction of anesthesia. One hundred surgical patients who required orotracheal intubation were randomly allocated into four groups. The first and third groups underwent fiberopt... | ['Adult', 'Aged', 'Analgesics, Opioid', 'Blood Pressure', 'Female', 'Fentanyl', 'Heart Rate', 'Hemodynamics', 'Humans', 'Intubation, Intratracheal', 'Laryngoscopy', 'Male', 'Middle Aged', 'Oxygen'] | 12,088,976 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.383.621.265'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Methods to establishment of serum induced syndrome of liver-depression and spleen-deficiency cell model]. | To explore the method of establishing a cell model of traditional Chinese medicine (TCM) syndromes, HepG2 cells were induced by human serum of liver-depression and spleen-deficiency syndrome(LDSDS) to establish a cell model of LDSDS in this research. The concentration of cells, the content of human serum in culture med... | ['Biomarkers', 'Humans', 'Liver', 'Metabolomics', 'Reproducibility of Results', 'Spleen'] | 30,111,061 | [['D23.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A10.549.700', 'A15.382.520.604.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Histopathological atlas of renal diseases: Acute post-streptococcal glomerulonephritis. | Acute post-streptococcal glomerulonephritis, also known as "proliferative-exudative nephritis" is morphologically characterized by intense endocapillary proliferation and massive accumulation of inflammatory cells. | ['Capillaries', 'Diagnosis, Differential', 'Glomerulonephritis', 'Humans', 'Kidney Glomerulus', 'Leukocytes', 'Renal Circulation', 'Streptococcal Infections'] | 15,593,046 | [['A07.015.461.165'], ['E01.171'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['G08.852.725', 'G09.330.100.812'], ['C01.150.252.410.890']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Guided bone regeneration in standardized calvarial defects using beta-tricalcium phosphate and collagen membrane: a real-time in vivo micro-computed tomographic experiment in rats. | Guided bone regeneration (GBR) procedures using graft materials have been used for reconstruction of osseous defects. The aim of the present in vivo micro-computed tomographic (µCT) and histologic study was to assess in real time the bone regeneration at GBR sites in standardized experimental calvarial defects (diamete... | ['Animals', 'Bone Regeneration', 'Calcium Phosphates', 'Collagen', 'Female', 'Osteogenesis', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Skull'] | 26,156,449 | [['B01.050'], ['G11.427.213.140', 'G16.762.150.150'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Microbial interactions: bacteria talk to (some of) their neighbors. | A recent study reports that Bacillus subtilis biofilm formation depends upon paracrine signaling where the signal-producing and target-responsive cells are different. | ['Bacillus subtilis', 'Bacterial Proteins', 'Biofilms', 'Escherichia coli', 'Extracellular Matrix', 'Lipopeptides', 'Membrane Proteins', 'Myxococcus xanthus', 'Paracrine Communication', 'Peptides, Cyclic', 'Quorum Sensing', 'Spores, Bacterial', 'Transferases'] | 19,706,277 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['A20.593', 'G06.120'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.284.295.310'], ['D10.477', 'D12.644.365'], ['D12.776.543'], ['B03.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiation dose reduction using a neck detection algorithm for single spiral brain and cervical spine CT acquisition in the trauma setting. | Cervical spine injuries occur in 4-8 % of adults with head trauma. Dual acquisition technique has been traditionally used for the CT scanning of brain and cervical spine. The purpose of this study was to determine the efficacy of radiation dose reduction by using a single acquisition technique that incorporated both an... | ['Algorithms', 'Brain', 'Brain Injuries', 'Cervical Vertebrae', 'Humans', 'Radiation Dosage', 'Tomography, Spiral Computed'] | 23,873,606 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E01.370.350.350.810.800', 'E01.370.350.600.350.700.810.800', 'E01.370.350.700.700.810.80... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The curious case of cyberchondria: A longitudinal study on the reciprocal relationship between health anxiety and online health information seeking. | The current study is the first to longitudinally investigate the reciprocal relationship between online health information seeking and health anxiety, i.e., cyberchondria. Expectations were that health anxious individuals who go online to find health information, experience an increase in health anxiety, which in turn ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Anxiety Disorders', 'Female', 'Humans', 'Information Seeking Behavior', 'Internet', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Young Adult'] | 27,497,667 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['F03.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.372', 'F01.145.535', 'L01.143.458'], ['L01.224.230.110.500'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival. | PURPOSE: Human chorionic gonadotropin (hCG) is produced by colorectalcancers and may play a role in its progression. The clinical and immunological effects of a synthetic vaccine targeting beta-hCG composed of the COOH terminal peptide of beta-hCG (CTP37) conjugated to diphtheria toxoid (DT) was investigated in patient... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antibodies, Neoplasm', 'Cancer Vaccines', 'Chorionic Gonadotropin', 'Colorectal Neoplasms', 'Diphtheria Toxin', 'Female', 'Humans', 'Immunotherapy', 'Male', 'Middle Aged', 'Recombinant Fusion Proteins', 'Safety', 'Survival Rate', 'Vaccination'] | 12,114,402 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.240', 'D12.776.124.790.651.114.240', 'D12.776.377.715.548.114.240'], ['D20.215.894.200'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['C04.588.274.476.411.307', 'C06.301.371.411.307',... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Propofol facilitated excitatory postsynaptic currents frequency on nucleus tractus solitarii (NTS) neurons. | Propofol, an intravenous anesthetic, is broadly used for general anesthesia and diagnostic sedations due to its fast onset and recovery. Propofol depresses respiratory and cardiovascular reflex responses, however, their underlying mechanisms are not well known. Cardiorespiratory information from visceral afferent vagus... | ['Anesthetics, Intravenous', 'Animals', 'Excitatory Postsynaptic Potentials', 'Male', 'Neurons, Afferent', 'Organ Culture Techniques', 'Propofol', 'Rats', 'Rats, Sprague-Dawley', 'Solitary Nucleus'] | 22,119,393 | [['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['B01.050'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['A08.675.650', 'A11.671.650'], ['E05.481.500.484'], ['D02.455.426.559.389.657.773'], ['B01.050.150.900.649.313.992.635.505.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of a site-specific recombination-based biosensor for detecting bioavailable toluene and related compounds on roots. | We constructed and characterized a plasmid-based genetic system that reports the expression of a toluene-responsive promoter (PtbuA1) by effecting an irreversible, heritable change in the biosensor cell. Expression of the reporter gene gfp is strongly repressed in the absence of expression from the PtbuA1 promoter, and... | ['Bacteria', 'Biosensing Techniques', 'Gene Expression Regulation', 'Genes, Plant', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Luminescent Proteins', 'Plant Roots', 'Plasmids', 'Promoter Regions, Genetic', 'Recombination, Genetic', 'Solvents', 'Toluene', 'Trichloroethylene'] | 12,662,171 | [['B03'], ['E05.601.043'], ['G05.308'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.024.340.435'], ['D12.776.532.265'], ['D12.776.532'], ['A18.400'], ['G05.360.600'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G05.728'], ['D27.720.844'], ['D02.455.426.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of the Dietary Approaches to Stop Hypertension, Physical Activity, and Their Combination with Semen Quality: A Cross-Sectional Study. | The influence of individual lifestyle factors is widely described in studies on semen quality. However, their synergistic effect is often neglected. The aim of the study was to examine the association between semen quality and dietary approaches to stop hypertension (DASH) diet, physical activity (PA), and the two sepa... | ['Adult', 'Cross-Sectional Studies', 'Dietary Approaches To Stop Hypertension', 'Exercise', 'Feeding Behavior', 'Humans', 'Hypertension', 'Infertility, Male', 'Life Style', 'Male', 'Middle Aged', 'Semen Analysis', 'Sperm Count', 'Sperm Motility', 'Young Adult'] | 31,877,862 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.642.249.475', 'G07.203.650.240.325'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C12.294.365.700'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The clastogenic potential in vitro of pyrrolizidine alkaloids employing hepatocyte metabolism. | Three pyrrolizidine alkaloids (PAs), monocrotaline, retrorsine and isatidine, were tested for their clastogenic activity under different conditions of metabolic activation in vitro. All three compounds exhibited a weak activity when V79 cells were treated at very high concentrations for 18 h in the absence of a metabol... | ['Animals', 'Biotransformation', 'Cell Line', 'Chromosome Aberrations', 'Liver', 'Liver Extracts', 'Monocrotaline', 'Mutagenicity Tests', 'Mutagens', 'Pyrrolizidine Alkaloids', 'Rats', 'Rats, Inbred Strains'] | 1,378,549 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['A03.620'], ['D20.777.351'], ['D03.132.716.500', 'D03.633.100.772.500'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['D03.132.716', 'D03.633.100.772'], ['B01.050.150.900.649.313.992.635.505.700']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bilateral subthalamic stimulation effects on oral force control in Parkinson's disease. | Dysarthria in Parkinson's disease (PD) consists of articulatory, phonatory and respiratory impairment. Bilateral subthalamic nucleus (STN) stimulation greatly improves motor disability, but its long-term effect on speech within a large group of patients has not been precisely evaluated. The aim of this study was to det... | ['Adult', 'Aged', 'Antiparkinson Agents', 'Articulation Disorders', 'Electric Stimulation Therapy', 'Electrodes, Implanted', 'Female', 'Follow-Up Studies', 'Humans', 'Levodopa', 'Male', 'Middle Aged', 'Movement', 'Neurosurgical Procedures', 'Parkinson Disease', 'Psychomotor Performance', 'Reaction Time', 'Speech Articu... | 12,574,948 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.427.090.050'], ['C10.597.606.150.500.800.150', 'C23.888.592.604.150.500.800.150'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conjugated linoleic acids attenuate FSH- and IGF1-stimulated cell proliferation; IGF1, GATA4, and aromatase expression; and estradiol-17â production in buffalo granulosa cells involving PPARã, PTEN, and PI3K/Akt. | Conjugated linoleic acid (CLA) has drawn much interest in last two decades in the area ranging from anticancer activity to obesity. A number of research papers have been published recently with regard to CLA's additional biological functions as reproductive benefits. However, not much is known how this mixture of isome... | ['Animals', 'Aromatase', 'Buffaloes', 'Cell Proliferation', 'Cells, Cultured', 'Estradiol', 'Female', 'Follicle Stimulating Hormone', 'GATA4 Transcription Factor', 'Gene Expression', 'Granulosa Cells', 'Insulin-Like Growth Factor I', 'Linoleic Acids, Conjugated', 'PPAR gamma', 'PTEN Phosphohydrolase', 'Phosphatidylinos... | 22,733,801 | [['B01.050'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['B01.050.150.900.649.313.500.380.135'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D04.210.500.365.415.248', 'D06... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemodilutional anemia impairs neurologic outcome after cardiopulmonary bypass in a piglet model. | OBJECTIVES: The effect of hemodilution on neurologic outcome after cardiopulmonary bypass remains unclear. We studied the influences of hematocrit on cerebral oxygenation and neuropathologic outcome in a piglet model.METHODS: Eleven piglets (9.3 +/- 1.1 kg) were randomized into 2 groups. Five piglets (group H) received... | ['Anemia', 'Animals', 'Blood Pressure', 'Body Temperature', 'Brain', 'Cardiopulmonary Bypass', 'Cytochromes a', 'Heart Rate', 'Hematocrit', 'Hemodilution', 'Hemoglobins', 'Monitoring, Intraoperative', 'Oxygen', 'Oxygen Consumption', 'Oxyhemoglobins', 'Spectroscopy, Near-Infrared', 'Sus scrofa'] | 17,198,777 | [['C15.378.071'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['E04.292.413'], ['D08.244.175.249', 'D12.776.422.220.175.249'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['E02.514'], ['D12.7... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Role and Effects of ANXA1 in Temporal Lobe Epilepsy: A Protection Mechanism? | BACKGROUND The endogenous protein annexin A1 (ANXA1) is an anti-inflammatory mediator in the brain that is thought to contribute to the progression of many neurological conditions. However, its exact role in temporal lobe epilepsy (TLE) remains unclear. We hypothesized that ANXA1 exerts negative actions on TLE by allev... | ['Animals', 'Annexin A1', 'Brain', 'Disease Models, Animal', 'Epilepsy, Temporal Lobe', 'Hippocampus', 'Male', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley'] | 26,609,771 | [['B01.050'], ['D12.776.157.125.050.050'], ['A08.186.211'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Two new phenylpropanoid esters from Bulbophyllum retusiusculum. | Two new phenylpropanoid esters bobulretulates A (1) and B (2), together with eleven known compounds, were isolated from the whole plants of Bulbophyllum retusiusculum. Their structures were elucidated by means of extensive spectroscopic analysis. | ['Esters', 'Orchidaceae', 'Phenylpropionates'] | 29,334,258 | [['D02.241.400'], ['B01.650.940.800.575.912.250.618.100.640'], ['D02.241.223.701']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medicare program; monthly actuarial rates and Part B premium rates beginning January 1, 1986--HCFA. Notice. | This notice announces the monthly actuarial rates for aged (age 65 or over) and disabled (under age 65) enrollees in the Medicare Supplementary Medical Insurance (SMI) program for calendar year 1986. It also announces the monthly SMI premium rate to be paid by all enrollees during calendar year 1986. | ['Actuarial Analysis', 'Centers for Medicare and Medicaid Services, U.S.', 'Fees and Charges', 'Insurance, Physician Services', 'Medicare', 'United States'] | 10,324,858 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['N03.219.442'], ['N03.219.521.576.343.616'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['Z01.107.567.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Stromal IGF-II messenger RNA in breast cancer: relationship with progesterone receptor expressed by malignant epithelial cells. | In breast cancer, insulin-like growth factor II (IGF-II) is stromal in origin and is considered an important regulator of tumour epithelium growth. The presence of progesterone receptor (PR) is expression of an intact oestrogen regulatory pathway of breast malignant epithelial cells and represents a parameter of cell d... | ['Breast Neoplasms', 'Epithelial Cells', 'Female', 'Fibroblasts', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Insulin-Like Growth Factor II', 'Middle Aged', 'RNA, Messenger', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Stromal Cells'] | 9,591,211 | [['C04.588.180', 'C17.800.090.500'], ['A11.436'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.57... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Disruption of tight junction structure in salivary glands from Sj?gren's syndrome patients is linked to proinflammatory cytokine exposure. | OBJECTIVE: Disorganization of acinar cell apical microvilli and the presence of stromal collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is impaired in patients with Sj?gren's syndrome. Tight junctions define cell polarity and regulate the paracellular flow of ions and water, c... | ['Adult', 'Aged', 'Biopsy', 'Claudin-1', 'Claudin-3', 'Claudin-4', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Interferon-gamma', 'Male', 'Membrane Proteins', 'Microscopy, Electron, Transmission', 'Middle Aged', 'Occludin', 'Phosphoproteins', 'RNA, Messenger', 'Salivary Glands', "Sjogren's Syndrome", 'Tight ... | 20,131,287 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D12.776.543.940.200.100'], ['D12.776.543.940.200.300'], ['D12.776.543.940.200.400'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.55... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pregnancy outcomes of Southeast Asian immigrant pregnant women compared with Thai pregnant women in Rajavithi Hospital. | OBJECTIVE: To determine the pregnancy outcomes of Southeast Asian immigrant women compared to native Thai women in Rajavithi Hospital.MATERIAL AND METHOD: A retrospective cohort study was conducted on singleton Southeast Asian immigrant pregnant women in Thailand between January 2007 and December 2008.RESULTS: One thou... | ['Adolescent', 'Adult', 'Apgar Score', 'Asia, Southeastern', 'Case-Control Studies', 'Delivery, Obstetric', 'Emigrants and Immigrants', 'Female', 'Humans', 'Incidence', 'Infant, Newborn', 'Odds Ratio', 'Population Surveillance', 'Postpartum Hemorrhage', 'Pregnancy', 'Pregnancy Outcome', 'Prenatal Care', 'Retrospective ... | 21,534,359 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.050'], ['Z01.252.145'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.520.252'], ['M01.189'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.85... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Interacton of Bdellovibrio bacteriovorus and host bacteria. I. Kinetic studies of attachment and invasion of Escherichia coli B by Bdellovibrio bacteriovorus. | Quantitative methods were developed for the study of the early stages in the interaction of Bdellovibrio bacteriovorus and host bacteria. Attachment measurements were based on the differential filtration of host and parasite. Invasion was measured by estimation of radioactively labeled Bdellovibrio cells remaining atta... | ['Azides', 'Bacteria', 'Bacteriolysis', 'Chloramphenicol', 'Escherichia coli', 'Iodoacetates', 'Kinetics', 'Puromycin', 'Streptomycin'] | 4,868,362 | [['D01.625.100', 'D02.159'], ['B03'], ['G06.099.115'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.081.018.487', 'D02.455.526.581.247'], ['G01.374.661', 'G02.111.490'], ['D02.241.223.200.380', 'D03.633.100.759.590.138.711',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of amylin binding sites in a human hepatoblastoma cell line. | Amylin binding sites in a human hepatoblastoma cell line (HepG2) have been characterized in detail. 125I-Amylin (rat) bound to HepG2 cells with high affinity. Binding was reversible and selective, and dependent on time and temperature. Scatchard analysis revealed the presence of high (Kd = 0.11 +/- 0.04 nM) and low (Kd... | ['Adenylyl Cyclases', 'Amyloid', 'Calcitonin Gene-Related Peptide', 'Carcinoma, Hepatocellular', 'Gluconeogenesis', 'Glycogen', 'Humans', 'Iodine Radioisotopes', 'Islet Amyloid Polypeptide', 'Liver Neoplasms', 'Receptors, Calcitonin', 'Receptors, Cell Surface', 'Receptors, Islet Amyloid Polypeptide', 'Receptors, Peptid... | 1,337,379 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['D05.500.049', 'D12.776.049'], ['D12.644.400.097', 'D12.776.631.650.097'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G02.111.158.500', 'G03.191.500'], ['D05.750.078.562.388', 'D09.698.365.388'], ['B01.050.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Iloperidone redux: a dissection of the Drug Approval Package for this newly commercialised second-generation antipsychotic. | OBJECTIVE: To describe the contents of a Drug Approval Package and to describe the efficacy and safety of iloperidone for the treatment of schizophrenia.DATA SOURCES: Drug Approval Package from the US Food and Drug Administration available at http://www.accessdata.fda.gov/drugsatfda_docs/nda/2009/022192s000TOC.cfm.DATA... | ['Adult', 'Antipsychotic Agents', 'Clinical Trials as Topic', 'Drug Approval', 'Humans', 'Isoxazoles', 'Piperidines', 'Psychiatric Status Rating Scales', 'Schizophrenia', 'Treatment Outcome', 'United States', 'United States Food and Drug Administration'] | 20,201,991 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.385'], ['D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Unilateral aural atresia in childhood: case selection and rehabilitation. | The classic management of children and adolescents with unilateral aural atresia, with or without microtia, is to assess audition, to exclude cholesteatoma formation both clinically and radiologically, to offer amplification in unilateral cases, and to consider surgical repair in bilateral cases. However, evidence indi... | ['Adolescent', 'Audiometry', 'Child', 'Congenital Abnormalities', 'Counseling', 'Ear, External', 'Female', 'Hearing Aids', 'Humans', 'Male', 'Patient Selection', 'Preoperative Care', 'Skin Transplantation'] | 7,674,443 | [['M01.060.057'], ['E01.370.382.375.060'], ['M01.060.406'], ['C16.131'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['A09.246.272'], ['E07.305.906.500', 'E07.814.458'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500.653', 'N04.590.731'], ['E02.760.795', 'E04.604.750', 'N02.421... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of development system on growth and reproductive performance of beef heifers. | Reproductive performance was evaluated in beef heifers born over a 2-yr period to determine the effects of target breeding weight (TBW) and development system (SYS) on growth and subsequent reproductive efficiency. Spring-born Angus heifers (253 ± 0.7 kg) were randomly allocated over 2 consecutive yr (yr 1, n = 80; yr ... | ['Animal Feed', 'Animal Husbandry', 'Animals', 'Breeding', 'Cattle', 'Diet', 'Eating', 'Female', 'Pregnancy', 'Reproduction', 'Seasons'] | 24,778,339 | [['G07.203.300.300.100', 'J02.500.300.100'], ['J01.040.090'], ['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['G08.686.784.769'], ['G08.686.784'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Role of endogenous basic fibroblast growth factor in the healing of gastric ulcers in rats. | Recently, it has been pointed out that growth factors play an important role in the healing of gastrointestinal ulcers. In the present study, we examined the role of endogenous basic fibroblast growth factor (bFGF) in the healing of gastric ulcers in the rat. In male SD rats, gastric ulcers were induced in the antrum b... | ['Animals', 'Anti-Ulcer Agents', 'Antibodies, Monoclonal', 'Cimetidine', 'Fibroblast Growth Factors', 'Gastric Acid', 'Gastric Mucosa', 'Humans', 'Male', 'Neovascularization, Physiologic', 'Rats', 'Rats, Sprague-Dawley', 'Recombinant Proteins', 'Stomach', 'Stomach Ulcer', 'Time Factors', 'Wound Healing'] | 9,032,135 | [['B01.050'], ['D27.505.954.483.203'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D02.078.370.200', 'D03.383.129.308.130'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['A12.200.307.603'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2,5-Dimethyl-4-hydroxy-3[2H]-furanone 6'O-malonyl-beta-D-glucopyranoside in strawberry fruits. | 2,5-Dimethyl-4-hydroxy-3[2H]-furanone 6'-O-malonyl-beta-D-glucopyranoside was isolated from a glycosidic extract of strawberry fruit (Fragaria x ananassa, cv. Senga Sengana) by means of countercurrent chromatography and reverse-phase HPLC. Identification was achieved by comparison of chromatographic and 1H, 13C and 2D-... | ['Chromatography, High Pressure Liquid', 'Countercurrent Distribution', 'Fruit', 'Furans', 'Glucosides', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry'] | 8,987,510 | [['E05.196.181.400.300'], ['E05.196.181.400.555', 'E05.196.278'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D03.383.312'], ['D09.408.348'], ['E05.196.867.519'], ['E05.196.566']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Changes in growth factor levels in human wound fluid. | BACKGROUND: It has been suggested that platelet-derived growth factor (PDGF) plays a central role in wound healing. Analysis of human wound fluid revealed the presence of PDGF AA (30 kd) and monocyte/macrophage-derived growth factor (MDGF) (12 to 14 kd) in the immediate postoperative period.METHODS: The amount of PDGF ... | ['3T3 Cells', 'Adolescent', 'Animals', 'Antibodies', 'Blotting, Western', 'Cell Division', 'Chemotaxis', 'DNA Replication', 'Humans', 'Interleukin-8', 'Kinetics', 'Mice', 'Orthopedics', 'Platelet-Derived Growth Factor', 'Wounds and Injuries'] | 1,621,222 | [['A11.251.210.100', 'A11.329.228.100'], ['M01.060.057'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.75... | ['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Spontaneous allocation of visual attention: dominant role of uniqueness. | Common sense suggests that unique or abruptly changing (transient) elements in a visual scene often draw attention involuntarily. Visual search studies paint a seemingly different picture, however Unique items usually draw attention involuntarily only when observers seek a unique target. One type of transient--abrupt o... | ['Attention', 'Humans', 'Visual Perception'] | 11,848,595 | [['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932']] | ['Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co-glycolide) microspheres: influence of the encapsulation technique and polymer purity on microsphere characteristics. | Recombinant human erythropoietin (EPO) and fluorescein isothiocyanate-labelled dextran (FITC-dextran) loaded biodegradable microspheres were prepared from poly(lactide-co-glycolide) (PLG) by a modified spray-drying technique. This microencapsulation method was compared with the water-in-oil-in-water (w/o/w) double-emul... | ['Calorimetry, Differential Scanning', 'Dextrans', 'Drug Compounding', 'Drug Stability', 'Erythropoietin', 'Fluorescein-5-isothiocyanate', 'Humans', 'Lactic Acid', 'Microscopy, Electron, Scanning', 'Microspheres', 'Molecular Weight', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Polymers', 'Recom... | 9,653,634 | [['E05.196.131.310', 'E05.196.370.310'], ['D05.750.078.562.272', 'D09.698.365.272'], ['E05.916.270'], ['E05.916.330'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Oxidative stress and oxygen status in ischemic stroke]. | A dynamic assessment of oxygen status of the arterial blood, activity of antioxidant system enzymes (AOS), succinatedehydrogenase (SDG), mitochondrial alpha-glycero-phosphate-dehydrogenase (alpha-GPDH) and alkaline phosphatase (AP) as well as concentrations of reduced glutathione (GSH) and secondary products of lipid p... | ['Aged', 'Aged, 80 and over', 'Alkaline Phosphatase', 'Biomarkers', 'Brain Infarction', 'Electroencephalography', 'Female', 'Follow-Up Studies', 'Glutathione', 'Glycerolphosphate Dehydrogenase', 'Humans', 'Lipid Peroxidation', 'Male', 'Middle Aged', 'Oxidative Stress', 'Oxygen Consumption', 'Prognosis', 'Succinate Dehy... | 17,310,794 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.352.650.035'], ['D23.101'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['E01.370.376.300', 'E01.370.405.245'], ['E05.318.372.500.750.249', 'N05.715.360.33... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Facile Preparation of a Thiol-Reactive (18)F-Labeling Agent and Synthesis of (18)F-DEG-VS-NT for PET Imaging of a Neurotensin Receptor-Positive Tumor. | UNLABELLED: Accumulating evidence suggests that neurotensin receptors (NTRs) play key roles in cancer growth and survival. In this study, we developed a simple and efficient method to radiolabel neurotensin peptide with (18)F for NTR-targeted imaging.METHODS: The thiol-reactive reagent (18)F-(2-(2-(2-fluoroethoxy)ethox... | ['Adenocarcinoma', 'Chemistry Techniques, Synthetic', 'Colonic Neoplasms', 'Drug Stability', 'HT29 Cells', 'Humans', 'Isotope Labeling', 'Neurotensin', 'Positron-Emission Tomography', 'Radiochemistry', 'Receptors, Neurotensin', 'Sulfhydryl Compounds', 'Tissue Distribution', 'Vinyl Compounds'] | 24,854,793 | [['C04.557.470.200.025'], ['E05.197', 'J01.897.836.249'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E05.916.330'], ['A11.251.210.190.475', 'A11.251.860.180.475', 'A11.436.365'], ['B01.050.150.900.649.313.988.400.112.400... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Serotonin level and turnover rate in brown adipose tissue of developing rats. | The level and turnover rate (TR) of serotonin (5-HT) were determined in the brown adipose tissue (BAT) of rats born and reared at 28 degrees C and 16 degrees C. The serotonin/norepinephrine ratio was high in BAT of both groups for the first 2 days. Thereafter it fell. During the first 3 days, the TR was three times hig... | ['Adipose Tissue, Brown', 'Animals', 'Animals, Newborn', 'Female', 'Fetus', 'Hydroxyindoleacetic Acid', 'Kinetics', 'Male', 'Norepinephrine', 'Rats', 'Rats, Sprague-Dawley', 'Serotonin', 'Temperature'] | 7,520,339 | [['A10.165.114.322'], ['B01.050'], ['B01.050.050.282'], ['A16.378'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['G01.374.661', 'G02.111.490'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['B01.050.150.900.649.313.992.635.505.700'], [... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Use of Unsintered Hydroxyapatite and Poly-L-lactic Acid Composite Sheets for Management of Orbital Wall Fracture. | Although unsintered hydroxyapatite and poly-L-lactic acid (u-HA/PLLA) composite sheets have various applications, such as in craniomaxillofacial fractures, orthognathic surgery, and orthopedic surgery, and have been proven to be safe and effective, no studies have reported the use of u-HA/PLLA composite sheets for orbi... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Diplopia', 'Durapatite', 'Enophthalmos', 'Female', 'Humans', 'Male', 'Middle Aged', 'Orbital Fractures', 'Orthognathic Surgical Procedures', 'Polyesters', 'Young Adult', 'Zygoma'] | 31,283,640 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['C10.597.751.941.339', 'C11.966.339', 'C23.888.592.763.941.339'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['C11.675.319'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Bulk leaf delta(18)O and delta(13)C reflect the intensity of intraspecific competition for water in a semi-arid tussock grassland. | We investigated the extent to which plant water and nutrient status are affected by intraspecific competition intensity and microsite quality in a monodominant tussock grassland. Leaf gas exchange and stable isotope measurements were used to assess the water relations of Stipa tenacissima tussocks growing along a gradi... | ['Carbon', 'Carbon Isotopes', 'Ecosystem', 'Oxygen', 'Oxygen Isotopes', 'Phosphorus', 'Photosynthesis', 'Plant Leaves', 'Plant Stomata', 'Plant Transpiration', 'Poaceae', 'Spain', 'Water'] | 19,552,668 | [['D01.268.150'], ['D01.268.150.075', 'D01.496.123'], ['G16.500.275.157', 'N06.230.124'], ['D01.268.185.550', 'D01.362.670'], ['D01.268.185.550.500', 'D01.362.670.300', 'D01.496.625'], ['D01.268.666'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['A18.0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Intracellular calcium homeostasis in patients with early stages of chronic kidney disease: effects of vitamin D3 supplementation. | BACKGROUND: Chronic renal failure has been referred to as a state of cellular calcium toxicity. The aim of this study was to investigate the status of free cytosolic calcium ([Ca(2+)](i)), intracellular calcium reserves and the capacitative calcium entry in peripheral blood mononuclear cells (PBMCs) of early-stage chro... | ['Adult', 'Aged', 'Calcium', 'Cholecalciferol', 'Chronic Disease', 'Dietary Supplements', 'Homeostasis', 'Humans', 'Kidney Diseases', 'Middle Aged', 'Receptors, Purinergic P2', 'Receptors, Purinergic P2X7'] | 19,531,669 | [['M01.060.116'], ['M01.060.116.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['C23.550.291.500'], ['G07.203.300.456', 'J02.500.456'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Raising the curtain on the gray region. | The gray region in EPA Document QA/G-4 is defined as the range of possible parameter values near the action level where the cost of determining that the alternative condition is true outweighs the expected consequences of a decision error. The gray region is also described as a range of true parameter values within the... | ['Decision Support Techniques', 'Environmental Monitoring', 'Humans', 'United States', 'United States Environmental Protection Agency'] | 12,008,893 | [['E05.245', 'L01.313.500.750.190'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875'], ['I01.409.418.750.937', 'N03.540.348.500.500.937']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Outcomes of mechanical stapling for postlaryngectomy open pharyngotomy closure. | OBJECTIVES/HYPOTHESIS: A total laryngectomy (TL) is performed as a primary or salvage therapy for laryngeal carcinoma. Pharyngotomy closure after TL is typically performed using manual sutures. Automatic stapling devices are routinely used in thoracoabdominal surgery, but have not been widely accepted for use in pharyn... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Cohort Studies', 'Disease-Free Survival', 'Equipment Design', 'Female', 'Follow-Up Studies', 'Humans', 'Laryngeal Neoplasms', 'Laryngectomy', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Retrospective Studies', 'Surgical Staplers', 'Surg... | 27,546,171 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.9... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metabolic and thermodynamic responses to dehydration-induced reductions in muscle blood flow in exercising humans. | 1. The present study examined whether reductions in muscle blood flow with exercise-induced dehydration would reduce substrate delivery and metabolite and heat removal to and from active skeletal muscles during prolonged exercise in the heat. A second aim was to examine the effects of dehydration on fuel utilisation ac... | ['Adult', 'Blood Glucose', 'Body Temperature', 'Carbon Dioxide', 'Dehydration', 'Epinephrine', 'Exercise', 'Exercise Test', 'Fatigue', 'Fatty Acids, Nonesterified', 'Fever', 'Glucagon', 'Glycerol', 'Glycogen', 'Humans', 'Insulin', 'Lactic Acid', 'Male', 'Muscle, Skeletal', 'Oxygen Consumption', 'Phosphocreatine', 'Regi... | 10,523,424 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.875.374', 'G07.110'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C18.452.950.179', 'C23.550.274'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['G11.427.410.698.277... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Pancreatic adaptation to dietary lipids is mediated by changes in lipase mRNA. | Lipase activity, rates of biosynthesis of lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) and amylase (1,4-alpha-D-glucan glucanohydrolase, EC 3.2.1.1) as well as concentrations of their corresponding mRNAs were measured in the pancreatic tissue of rats fed isocaloric and isoprotein diets with inverse changes in the... | ['Amylases', 'Animals', 'Dietary Fats', 'Lipase', 'Male', 'Pancreas', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'Sulfur Radioisotopes'] | 2,465,787 | [['D08.811.277.450.066'], ['B01.050'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D08.811.277.352.100.400'], ['A03.734'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D01.268.185.900.500.690', 'D01.496.749.858',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study. | OBJECTIVE: To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation.DESIGN: Prospective, randomized clinical study.SETTING: Institute of Reproductive Medicine, Kolkata, India.PATIENT(S): A total of 1,373 infertile women undergoing IVF parti... | ['Abortion, Spontaneous', 'Administration, Intravaginal', 'Administration, Oral', 'Adult', 'Capsules', 'Dydrogesterone', 'Female', 'Fertility Agents, Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Female', 'Luteal Phase', 'Pregnancy', 'Pregnancy Rate', 'Progesterone', 'Vaginal Creams, Foams, and Jellies', '... | 21,333,984 | [['C13.703.039', 'G08.686.784.769.496.125'], ['E02.319.267.120.500'], ['E02.319.267.100'], ['M01.060.116'], ['D26.255.150'], ['D04.210.500.745.432.296'], ['D27.505.696.875.552.344', 'D27.505.954.705.552.344'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin. | LFA-1 (áLâ2) and Mac-1 (áMâ2) integrins regulate leukocyte trafficking in health and disease by binding primarily to IgSF ligand ICAM-1 and ICAM-2 on endothelial cells. Here we have shown that the anti-coagulant molecule thrombomodulin (TM), found on the surface of endothelial cells, functions as a potentially new liga... | ['CD18 Antigens', 'Cell Adhesion', 'Humans', 'Leukocytes, Mononuclear', 'Lymphocyte Function-Associated Antigen-1', 'Macrophage-1 Antigen', 'Mutation', 'Protein Binding', 'Protein Interaction Domains and Motifs', 'Thrombomodulin'] | 27,055,590 | [['D12.776.395.550.200.275.750', 'D12.776.543.550.200.275.750', 'D12.776.543.750.705.408.200.249', 'D12.776.543.750.705.408.600.100.750', 'D12.776.543.750.705.833.249.750', 'D23.050.301.264.894.118', 'D23.050.301.350.275.750', 'D23.101.100.894.118'], ['G04.022'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of the Effect of Enteral Lipid Sensing on Endogenous Glucose Production in Humans. | Administration of lipids into the upper intestine of rats has been shown to acutely decrease endogenous glucose production (EGP) in the preabsorptive state, postulated to act through a gut-brain-liver axis involving accumulation of long-chain fatty acyl-CoA, release of cholecystokinin, and subsequent neuronal signaling... | ['Blood Glucose', 'Emulsions', 'Fatty Acids, Nonesterified', 'Glucagon', 'Humans', 'Insulin', 'Lipid Metabolism', 'Male', 'Middle Aged', 'Phospholipids', 'Soybean Oil', 'Triglycerides'] | 25,754,959 | [['D09.947.875.359.448.500'], ['D20.280.260', 'D26.255.165.260'], ['D10.251.310'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.458'], ['M01.060.116.630'], ['D10.570.755'], ['D10.212.302.380... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The functional vanGCd cluster of Clostridium difficile does not confer vancomycin resistance. | vanGCd, a cryptic gene cluster highly homologous to the vanG gene cluster of Enterococcus faecalis is largely spread in Clostridium difficile. Since emergence of vancomycin resistance would have dramatic clinical consequences, we have evaluated the capacity of the vanGCd cluster to confer resistance. We showed that exp... | ['Anti-Bacterial Agents', 'Bacteria', 'Bacterial Proteins', 'Clostridioides difficile', 'Drug Resistance, Microbial', 'Enterococcus', 'Enterococcus faecalis', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Genetic Complementation Test', 'Microbial Sensitivity Tests', 'Multige... | 23,782,343 | [['D27.505.954.122.085'], ['B03'], ['D12.776.097'], ['B03.353.625.657.500'], ['G06.225', 'G07.690.773.984.269'], ['B03.353.750.250.250', 'B03.510.550.250.250'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['E05.393.332'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An outbreak of shigellosis in a child care centre. | Outbreaks of shigellosis in child care are not commonly reported in Australia, however Shigella bacteria can easily spread in these settings. We report an outbreak of shigellosis in a child care centre and discuss the control measures implemented. This investigation identified 20 confirmed cases of Shigella sonnei biot... | ['Adolescent', 'Adult', 'Age Distribution', 'Child', 'Child Day Care Centers', 'Child, Preschool', 'Disease Outbreaks', 'Dysentery, Bacillary', 'Female', 'Food Contamination', 'Food Microbiology', 'Humans', 'Incidence', 'Infection Control', 'Male', 'Middle Aged', 'Risk Assessment', 'Sanitation', 'Severity of Illness In... | 15,460,959 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['J03.160', 'N02.421.143.098'], ['M01.060.406.448'], ['N06.850.290'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Mechanical and Finite Element Analysis of an Innovative Orthopedic Implant Designed to Increase the Weight Carrying Ability of the Femur and Reduce Frictional Forces on an Amputee's Stump. | This study was designed to test the hypothesis that: "A properly designed implant that harnesses the principle of the incompressibility of fluids can improve the weight carrying ability of an amputee's residual femur and reduce the frictional forces at the stump external socket interface." The hypothesis was tested bot... | ['Amputation Stumps', 'Biomechanical Phenomena', 'Femur', 'Finite Element Analysis', 'Friction', 'Humans', 'Prostheses and Implants', 'Prosthesis Design', 'Weight-Bearing'] | 30,901,446 | [['A01.378.100'], ['G01.154.090', 'G01.374.089'], ['A02.835.232.043.150'], ['E05.355'], ['G01.374.618'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695'], ['E05.320.550', 'E07.695.680'], ['G01.374.965']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relative fitness can decrease in evolving asexual populations of S. cerevisiae. | It is generally accepted from the darwinian theory of evolution that a progressive increase in population adaptation will occur in populations containing genetic variation in fitness, until a stable equilibrium is reached and/or the additive genetic variation is exhausted. However, the theoretical literature of populat... | ['Biological Evolution', 'Diploidy', 'Epistasis, Genetic', 'Genetic Variation', 'Genotype', 'Haploidy', 'Mutation', 'Reproduction, Asexual', 'Saccharomyces cerevisiae'] | 16,752,492 | [['G05.045', 'G16.075'], ['G05.700.264'], ['G05.308.207'], ['G05.365'], ['G05.380'], ['G05.700.456'], ['G05.365.590'], ['G08.686.784.830'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extracorporeal shock wave lithotripsy and intravenous contrast media application for localization of radiolucent calculi. | BACKGROUND AND PURPOSE: The present study was carried out to compare the efficacy of ESWL treating radiolucent ureteric calculi visible in the ureter after application of contrast media.MATERIAL AND METHODS: Medical records of 47 patients who had verified ureteric calculi by intravenous urography and retrograde pyelogr... | ['Adult', 'Contrast Media', 'Female', 'Humans', 'Infusions, Intravenous', 'Lithotripsy', 'Male', 'Middle Aged', 'Radiography, Interventional', 'Ureteral Calculi', 'Young Adult'] | 21,585,180 | [['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E02.600', 'E04.943.500'], ['M01.060.116.630'], ['E01.370.350.700.725', 'E04.502.780'], ['C12.777.725.938.500', 'C12.777.967.374.500', 'C12.777.967.500.851', 'C13.351.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antioxidant action of extract of the traditional medicinal plant Rhazya stricta Decne. in rats. | The effects of a leaf extract of the traditional medicinal plant Rhazya stricta (0.25, 1.0 and 4.0 g/kg/day for 3 days) on reduced glutathione (GSH), lipid peroxidation (LP) and ascorbic acid (AA) concentrations in the liver and kidneys were studied in rats 24 h after the last dose. The plant extract, at a dose of 0.25... | ['Animals', 'Antioxidants', 'Ascorbic Acid', 'Glutathione', 'Kidney', 'Lipid Peroxidation', 'Liver', 'Male', 'Medicine, Traditional', 'Plant Extracts', 'Plant Leaves', 'Rats', 'Rats, Wistar', 'Saudi Arabia'] | 10,960,906 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D12.644.456.448'], ['A05.810.453'], ['G02.111.515', 'G03.295.531.587'], ['A03.620'], ['E02.190.488', 'I01.076.201.450.654'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['B0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
The effect of cilostazol on right heart function and pulmonary pressure. | INTRODUCTION: Cilostazol is a PDE3 inhibitor and used to treat peripheral arterial disease. There are few reports on the influence of cilostazol on heart.AIMS: The aim of this study was to assess this effect on right ventricular function and pulmonary artery pressure.METHODS: Forty patients with normal left and right v... | ['Aged', 'Cilostazol', 'Familial Primary Pulmonary Hypertension', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Phosphodiesterase 3 Inhibitors', 'Pulmonary Artery', 'Tetrazoles', 'Ventricular Function, Right'] | 23,911,039 | [['M01.060.116.100'], ['D03.383.129.617.293', 'D03.633.100.810.069'], ['C08.381.423.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.116.630'], ['D27.505.519.389.735.249'], ['A07.015.114.715'], ['D03.383.129.617'], ['G09.330.955.900']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Location of medical education and choice of location of practice. | The geographical distribution of physicians is affected by a number of factors, including the location of their medical education. The authors of the present paper examined the physicians' decisions on where to locate after they completed their training by determining where a state's practicing physicians come from and... | ['Education, Medical', 'Female', 'Foreign Medical Graduates', 'Male', 'Physicians', 'Physicians, Women', 'Private Practice', 'Schools, Medical', 'United States'] | 3,723,565 | [['I02.358.399'], ['M01.526.407.435', 'M01.526.485.810.390', 'N02.360.810.390'], ['M01.526.485.810', 'N02.360.810'], ['M01.526.485.810.820', 'M01.975.790', 'N02.360.810.820'], ['N04.452.758.745'], ['I02.783.495.552', 'N02.278.020.578'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Enhanced proliferation of progenitor cells following long-term potentiation induction in the rat dentate gyrus. | The dentate gyrus (DG) is among the few areas in the mammalian brain where production of new neurons continues in the adulthood. Although its functional significance is not completely understood, several lines of evidence suggest the role of DG neurogenesis in learning and memory. Considering that long-term potentiatio... | ['Adult Stem Cells', 'Animals', 'Cell Proliferation', 'Dentate Gyrus', 'Electric Stimulation', 'Long-Term Potentiation', 'Male', 'Perforant Pathway', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate', 'Statistics, Nonparametric', 'Synapses'] | 16,824,772 | [['A11.872.040'], ['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['E05.723.402'], ['G11.561.638.350'], ['A08.186.211.180.730', 'A08.612.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D12.776... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pedobacter huanghensis sp. nov. and Pedobacter glacialis sp. nov., isolated from Arctic glacier foreland. | Two psychrotolerant, Gram-stain-negative, rod-shaped bacterial strains, designed M1-27(T) and 8-24(T), were subjected to polyphasic taxonomic studies. Strain M1-27(T) was isolated from the foreland of the Midtre Lov?nbreen glacier, whereas strain 8-24(T) was isolated from the foreland of the Austre Lov?nbreen glacier. ... | ['Arctic Regions', 'Bacterial Typing Techniques', 'Base Composition', 'DNA, Bacterial', 'Fatty Acids', 'Ice Cover', 'Molecular Sequence Data', 'Pedobacter', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Svalbard', 'Vitamin K 2'] | 24,763,603 | [['Z01.208'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['D13.444.308.212'], ['D10.251'], ['G01.311.400', 'G16.500.275.410.500', 'N06.230.291.500'], ['L01.453.245.667'], ['B03.440.080.600', 'B03.440.400.425.611'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['E05.393.7... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Design of antibiotic containing hydrogel wound dressings: biomedical properties and histological study of wound healing. | Keeping in view the antioxidant nature of the acacia gum and mucoadhesive nature of carbopol hydrogels, in the present studies, an attempt has been made to explore the potential of these materials in designing new hydrogel wound dressings meant for slow release of gentamicin, an antibiotic drug, and to enhance the woun... | ['Animals', 'Anti-Bacterial Agents', 'Antioxidants', 'Bandages', 'Drug Design', 'Gentamicins', 'Hydrogels', 'Mice', 'Mice, Inbred BALB C', 'Pseudomonas', 'Skin', 'Staphylococcus', 'Tensile Strength', 'Wound Healing'] | 24,075,861 | [['B01.050'], ['D27.505.954.122.085'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E07.101'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D09.408.051.374'], ['D20.280.320.375', 'D26.255.165.320.375'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.33... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective effects of cyanide (100 microM) on the excitatory amino acid-induced elevation of intracellular calcium levels in neuronal culture. | The effect of low concentrations of cyanide on the excitatory amino acid-induced elevations of intracellular calcium levels ([Ca2+]i) was studied in cerebellar granule cells using ratio fluorometry with fura-2. Glutamate, kainate, N-methyl-D-aspartate (NMDA), quisqualate (50 microM, each) and membrane depolarization by... | ['Amino Acids', 'Animals', 'Calcium', 'Cells, Cultured', 'Cerebellum', 'Diltiazem', 'Glutamates', 'Glutamic Acid', 'Kainic Acid', 'Lanthanum', 'Membrane Potentials', 'N-Methylaspartate', 'Neurons', 'Potassium Chloride', 'Quisqualic Acid', 'Rats', 'Rats, Inbred Strains', 'Sodium Cyanide'] | 1,353,614 | [['D12.125'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['A08.186.211.132.810.428.200'], ['D03.633.100.079.150'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D03.383.773.400'], ['D01.268.558.362.500', 'D01.552.550.39... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental alteration and phenotypic regulation of Candida albicans adhesion to plastic. | The adhesion of Candida albicans to plastic was examined after growth in two chemically defined media, Lee-Buckley-Campbell (LBC) and yeast nitrogen base (YNB), by binding isotherms, Langmuir isotherms, and Scatchard plots, and the number of binding sites (N) and the affinity constants (K) were calculated. K and N were... | ['Adhesiveness', 'Candida albicans', 'Culture Media', 'Detergents', 'Osmolar Concentration', 'Phenotype', 'Plastics'] | 2,680,985 | [['G02.860.139'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D27.720.470.305', 'E07.206'], ['D27.720.877.265', 'J01.516.381'], ['G02.640'], ['G05.695'], ['D05.750.716', 'D25.720.716', 'J01.637.051.720.716']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Artificial neural networks and geometric morphometric methods as a means for classification: A case-study using teeth from Carcharhinus sp. (Carcharhinidae). | Over the past few decades, geometric morphometric methods have become increasingly popular and powerful tools to describe morphological data while over the same period artificial neural networks have had a similar rise in the classification of specimens to preconceived groups. However, there has been little research in... | ['Animals', 'Neural Networks, Computer', 'Sharks', 'Species Specificity', 'Tooth'] | 27,892,600 | [['B01.050'], ['G17.485', 'L01.224.050.375.605'], ['B01.050.150.900.493.370.853'], ['G16.824'], ['A14.549.167.860']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Delayed sleep phase syndrome: A placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset. | In a double-blind placebo-controlled cross-over study, 30 patients with Delayed Sleep Phase Syndrome (DSPS) were included, of whom 25 finished the study. Melatonin 5 mg was administered during two weeks in a double-blind setting and two weeks in an open setting successively or interrupted by two week of placebo. The st... | ['Adult', 'Antioxidants', 'Body Temperature', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Humans', 'Light', 'Male', 'Melatonin', 'Middle Aged', 'Sleep Wake Disorders', 'Sleep, REM', 'Syndrome', 'Time Factors'] | 9,682,186 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E01.370.600.875.374', 'G07.110'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improvement of the quantitative method for glucose determination using hexokinase and glucose 6-phosphate dehydrogenase. | This paper has two aims. The first one is to point out the shortcomings of Food and Drug Administration's (FDA's) reference method for the measurement of glucose. We found that the quantity of enzyme used in the method recommended by the FDA was more than the exact quantity needed for accurate measurement. The use of e... | ['Adenosine Triphosphate', 'Blood Glucose', 'Colorimetry', 'Enzyme Inhibitors', 'Glucosephosphate Dehydrogenase', 'Hexokinase', 'Humans', 'Hydrogen-Ion Concentration', 'Reference Standards'] | 11,434,388 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D09.947.875.359.448.500'], ['E05.196.922.250'], ['D27.505.519.389'], ['D08.811.682.047.150.300'], ['D08.811.913.696.620.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.978.808']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of age-related dopaminergic neuron loss in the substantia nigra on the circadian rhythms of locomotor activity in mice. | Elderly people often develop sleep and autonomic dysfunctions, which are regulated by circadian rhythm. Recently, we reported on the degradation of neural output from the central circadian clock in the suprachiasmatic nucleus (SCN) with aging. However, it is likely that many other factors contribute to the age-related ... | ['1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine', 'Aging', 'Animals', 'Circadian Rhythm', 'Dopamine Agents', 'Dopaminergic Neurons', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Motor Activity', 'Nerve Degeneration', 'Substantia Nigra'] | 23,044,185 | [['D03.383.725.450'], ['G07.345.124'], ['B01.050'], ['G07.180.562.190'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['A08.675.278', 'A11.671.270'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensory innervation of periodontal ligament of rat molars consists of unencapsulated Ruffini-like mechanoreceptors and free nerve endings. | The trigeminal ganglion (TG) of adult rats was injected with 3H-amino acids to label periodontal receptors by axonal transport; 20-24 hours after injection, samples of molar ligament were prepared for autoradiography and electron microscopy. Four types of neurites labeled from TG were found in the avascular ligament fi... | ['Animals', 'Axons', 'Male', 'Mechanoreceptors', 'Microscopy, Electron', 'Molar', 'Nerve Endings', 'Periodontal Ligament', 'Rats', 'Rats, Inbred Strains', 'Trigeminal Nerve'] | 3,968,252 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['E01.370.350.515.402', 'E05.595.402'], ['A14.549.167.860.525'], ['A08.800.550'], ['A14.549.167.646.771'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Allergic rhinitis and recurrent epistaxis in children. | BACKGROUND: Many allergists, but few otolaryngologists, consider allergic rhinitis to be a common cause of nosebleeds in childhood.OBJECTIVE: To determine whether the two conditions are related, and whether epistaxis could be due solely to the local effects of nasal symptoms.METHODS: We studied 557 children who were re... | ['Adolescent', 'Child', 'Child, Preschool', 'Epistaxis', 'Female', 'Humans', 'Hypersensitivity', 'Infant', 'Male', 'Recurrence', 'Regression Analysis', 'Rhinitis'] | 7,719,879 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C08.460.261', 'C09.603.261', 'C23.550.414.712', 'C23.888.852.040'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['M01.060.703'], ['C23.550.291.937'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['C01.748.674', 'C08.460.79... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Environmental factors and asthma in the child population of Vizcaya]. | Authors have studied relationship of several environmental factors (climatic changes and atmospheric pollution) and occurrence of asthma in childhood population of Vizcaya. Sample studied was composed of 290 asthmatic children and the same normal controls as counterpart exposed to equal risk. They also consider data ob... | ['Asthma', 'Child', 'Climate', 'Environmental Pollutants', 'Humans', 'Nitrogen Oxides', 'Spain', 'Sulfur Dioxide'] | 3,178,054 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['G16.500.275.071', 'N06.230.300.100.250'], ['D27.888.284'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.362.635', 'D01.625.550', 'D01.650.550.587'], ['Z01.542.846'], ['D01.362.810', 'D01.650.550.850.925', 'D01.875.82... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The incidence of primary dysmenorrhea in teenagers. | By means of a questionnaire we studied the menstrual patterns of 502 adolescent girls aged 10--19 years in 1979. The incidence of occasional or consistent primary dysmenorrhea was 43%. The incidence of dysmenorrhea increased considerably with increasing age and the interval between the menarche and the onset of dysmeno... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Dysmenorrhea', 'Female', 'Humans', 'Menarche', 'Surveys and Questionnaires', 'Sweden'] | 7,247,462 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['C23.550.568.750', 'C23.888.592.612.944.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760.410', 'G08.686.841.374.410'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.542.816.500']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Risk assessment of trace elements in sediments: the case of the estuary of the Nerbioi-Ibaizabal River (Basque Country). | Long term (January 2005-January 2008) monitoring of sediments was used to investigate metal pollution in the estuary of the Nerbioi-Ibaizabal River (Bilbao, Basque Country). Sediments were collected from eight representative locations of the estuary approximately every three months. The concentration of fourteen elemen... | ['Environmental Monitoring', 'Environmental Pollution', 'Geologic Sediments', 'Risk Assessment', 'Rivers', 'Spain', 'Trace Elements', 'Water Pollutants, Chemical'] | 20,542,636 | [['N06.850.460.350.080', 'N06.850.780.375'], ['N06.850.460'], ['G01.311.330', 'G16.500.320'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['Z01.542.846'], ['D01.268.811', 'D27.... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Comparison of Patient Characteristics and Course of Hypertensive Hypokinetic Cardiomyopathy Versus Idiopathic Dilated Cardiomyopathy. | Hypertensive hypokinetic cardiomyopathy (HHC) is defined by left ventricular (LV) systolic dysfunction with a history of systemic hypertension as the only possible cause. Although commonly encountered in clinical practice, its characterization and differences with true idiopathic dilated cardiomyopathy (IDC) are lackin... | ['Adrenergic beta-Antagonists', 'Adult', 'Aged', 'Amiodarone', 'Angiotensin Receptor Antagonists', 'Angiotensin-Converting Enzyme Inhibitors', 'Anti-Arrhythmia Agents', 'Cardiomyopathies', 'Cardiomyopathy, Dilated', 'Cause of Death', 'Disease Progression', 'Female', 'Heart Failure', 'Heart Transplantation', 'Heart-Assi... | 27,988,039 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['M01.060.116.100'], ['D03.633.100.127.075'], ['D27.505.519.162'], ['D27.505.519.389.745.085'], ['D27.505.954.411.097'], ['C14.280.238'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['E05.318.308.985.550.250', 'N01.224.935.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adsorption in vitro to Escherichia coli of antibodies and other proteins in bovine serum and colostrum and its effects on the production of E. coli agglutinins. | IgGl, IgG2, IgA and IgM from bovine serum and colostrum are adsorbed by Escherichia coli in vitro; lactoferrin is also adsorbed from colostrum and alpha2 macroglobulin from serum. The colostral adsorbed proteins on E. coli appear to reduce formation of agglutinins when the treated bacteria are injected into rabbits and... | ['Adsorption', 'Agglutinins', 'Animals', 'Antibodies', 'Cattle', 'Colostrum', 'Escherichia coli', 'Female', 'Guinea Pigs', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Lactoferrin', 'Rabbits'] | 1,095,472 | [['G01.030', 'G02.020'], ['D27.505.696.477.136', 'D27.505.954.502.270.232'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.150.900.649.313.500.380.271'], ['A12.200.194'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.992.550... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Work-family conflict, gender, and health-related outcomes: a study of employed parents in two community samples. | On the basis of identity theory and research on sex role socialization, it was predicted that both work interfering with family (W-->F conflict) and family interfering with work (F-->W conflict) are uniquely related to depression, poor physical health, and heavy alcohol use (Hypothesis 1). It also was predicted that ge... | ['Adult', 'Alcohol Drinking', 'Conflict, Psychological', 'Data Collection', 'Depressive Disorder', 'Employment', 'Family Relations', 'Female', 'Gender Identity', 'Health Status', 'Humans', 'Male', 'Sex Factors', 'Stress, Psychological', 'Workload'] | 9,547,034 | [['M01.060.116'], ['F01.145.317.269'], ['F01.658.209'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F03.600.300'], ['N01.824.245'], ['F01.829.263.370', 'I01.880.853.150.439'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['I01.240.425', 'N01.224.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Population genetics of blood group polymorphisms in a sample of newborns from Melbourne, Australia. | Blood from 304 newborn infants of Melbourne, Australia, was examined for 9 polymorphic systems (red cell antigens ABO, MNSs, Rh, Kell, Duffy and Kidd, the red cell enzyme ESD and serum proteins GC and TF) in order to investigate the evolution of the Melbourne gene pool since 1975. Immigration patterns have changed cons... | ['Australia', 'Blood Group Antigens', 'Gene Frequency', 'Haplotypes', 'Humans', 'Infant, Newborn', 'Phenotype', 'Polymorphism, Genetic'] | 3,759,106 | [['Z01.639.100', 'Z01.678.100.373'], ['D23.050.301.290', 'D23.050.705.230'], ['G05.330'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G05.695'], ['G05.365.795']] | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Neonatal Diesel Exhaust Particulate Exposure Does Not Predispose Mice to Adult Cardiac Hypertrophy or Heart Failure. | Background: We have previously reported that in utero and early life exposure to diesel exhaust particulates predisposes mice to adult heart failure, and that in utero exposure alone is sufficient to confer this predisposition. This follow up study addresses whether neonatal exposure alone can also confer this predispo... | ['Aging', 'Animals', 'Animals, Newborn', 'Cardiomegaly', 'Disease Susceptibility', 'Echocardiography', 'Follow-Up Studies', 'Heart Failure', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Particulate Matter', 'Vehicle Emissions'] | 27,886,143 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['C14.280.195', 'C23.300.775.250'], ['C23.550.291.687', 'G07.100.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['B01.050.150.900... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Emergency department use after pediatric pharmaceutical ingestion: comparison of two national databases. | BACKGROUND: As no "gold standard" measure exists for the number of children evaluated in emergency departments (EDs) for medication-related injuries, the public health impact is based on estimates. In January 2006 the Morbidity and Mortality Weekly Report published a National Electronic Injury Surveillance System-All I... | ['Age Factors', 'Child, Preschool', 'Databases, Factual', 'Emergency Service, Hospital', 'Female', 'Hospitalization', 'Humans', 'Infant', 'Male', 'Pharmaceutical Preparations', 'Poisoning', 'Reference Standards', 'United States'] | 20,070,181 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406.448'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D26'], ['C25.723'], ['E05.9... | ['Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Parallel synthesis of 7-heteroaryl-pyrazolo[1,5-a]pyrimidine-3-carboxamides. | A simple and practical four-step protocol for the parallel synthesis of 7-heteroaryl-pyrazolo[1,5-[Formula: see text]]pyrimidine-3-carboxamides was developed. The synthesis starts with transformation of commercially available 2-acetylpyridine and acetylpyrazine with [Formula: see text] [Formula: see text]-dimethylforma... | ['Combinatorial Chemistry Techniques', 'Cyclization', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Pyrazoles', 'Pyrimidines'] | 23,975,596 | [['E05.197.312', 'J01.897.836.249.249'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['G02.111.570', 'G02.466'], ['E05.196.867.519.550'], ['D03.383.129.539'], ['D03.383.742']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Positioning an intraaortic balloon pump using intraoperative transesophageal echocardiogram guidance. | A 72-year-old man with an ejection fraction of 25% is scheduled to undergo elective coronary artery bypass graft using cardiopulmonary bypass. Because of the high-risk nature of the operation, the surgeon wants to insert an intraaortic balloon pump (IABP) before initiating cardiopulmonary bypass. An intraoperative tran... | ['Aged', 'Echocardiography, Transesophageal', 'Humans', 'Intra-Aortic Balloon Pumping', 'Male', 'Monitoring, Intraoperative', 'Patient Positioning'] | 21,467,559 | [['M01.060.116.100'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.050.215.400'], ['E01.370.520.510', 'E04.510'], ['E02.760.670', 'N02.421.585.700']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Licensing: pros and cons for biotech. | This article guides the reader through strategic considerations when facing the option to license a drug development project. It is crucial to understand these licensing events in their full complexity in order to achieve maximum value for the company and the shareholders, while minimizing risk. First, the nature of va... | ['Biotechnology', 'Contract Services', 'Decision Making', 'Drug Design', 'Drug Industry', 'Legislation, Drug', 'Licensure'] | 19,200,456 | [['H01.158.550', 'J01.897.120'], ['N03.219.463.100'], ['F02.463.785.373'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['J01.576.655.750'], ['I01.880.604.605', 'N03.706.615.402'], ['N03.706.110.510', 'N05.700.200.450']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Adenovirus-mediated gene transfer in the transplant setting. Part III. Variables affecting gene transfer in liver grafts. | We have established a system of efficient gene transfer to liver grafts using adenovirus vectors. The purpose of this study was to examine variables affecting gene transfer to rat liver grafts during cold preservation. Our results demonstrate that gene transfer efficiency was directly correlated with the ratio of vecto... | ['Adenoviridae', 'Animals', 'Biopsy', 'Cryopreservation', 'Gene Transfer Techniques', 'Genetic Vectors', 'Liver', 'Liver Transplantation', 'Male', 'Organ Preservation', 'Rats', 'Rats, Inbred BN', 'Recombinant Proteins'] | 7,886,789 | [['B04.280.030'], ['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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