Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Swiss hypertension treatment programme with verapamil and/or enalapril in diabetic patients. | The purpose of the present study was to assess the efficacy and tolerability of diuretic-free antihypertensive therapy with a calcium antagonist and/or an angiotensin converting enzyme (ACE) inhibitor in patients with diabetes mellitus. 54 hypertensive [blood pressure (BP) above 140/90mm Hg] patients with diabetes mell... | ['Adolescent', 'Adult', 'Aged', 'Blood Glucose', 'Blood Pressure', 'Creatinine', 'Diabetes Complications', 'Drug Therapy, Combination', 'Enalapril', 'Female', 'Humans', 'Hypertension', 'Lipids', 'Male', 'Middle Aged', 'Switzerland', 'Verapamil'] | 1,283,588 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.383.129.308.207'], ['C19.246.099'], ['E02.319.310'], ['D12.644.456.345.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D10'], ['M01.060.116.630'], ['Z01.542.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Microbial contamination of raw meat and its environment in retail shops in Karachi, Pakistan. | BACKGROUND: This study was conducted to examine the frequency of contamination in retail meat available in Karachi, Pakistan.METHODOLOGY: Raw meat samples (250) and surface swabs (90) from meat processing equipment and the surrounding environment were analyzed for microbiological contamination.RESULTS: Out of 340 sampl... | ['Bacteria', 'Colony Count, Microbial', 'Drug Resistance, Bacterial', 'Environmental Microbiology', 'Humans', 'Meat', 'Microbial Viability', 'Pakistan', 'Prevalence'] | 20,601,790 | [['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['H01.158.273.540.274', 'N06.850.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.600', 'J02.500.600'], ['G06.580'], ['Z01.252.245.723'], ['E05.318.308.985.525.750', 'N01.224.935.597.750... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
[Hiatal hernia. Symptoms, diagnosis and therapy]. | Forty-eight patients with a mean age of 53 years were treated for hiatal hernia at the University of W?rzburg Department of Surgery between 1983 and 1989. The cohort was subdivided according to type of herniation, age and sex, and symptoms. Conservative treatment sufficed in 22%, but the majority (78%) underwent surger... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Esophagoscopy', 'Female', 'Gastric Fundus', 'Gastroesophageal Reflux', 'Hernia, Hiatal', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Pyloric Antrum'] | 1,927,088 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['A03.556.875.875.419'], ['C06.405.117.119.500.484'], ['C23.300.707.960.500.467'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rapid binding of beta 2-microglobulin to renal brush-border membranes. | 125I-labelled human beta 2-microglobulin binding to rat renal brush-border membranes was assessed by an in vitro assay under near physiological incubation conditions (i.e. low content of albumin). Binding rate was 55 pmol/min per mg protein in the presence of 200 nM of beta 2-microglobulin and degradation rate was negl... | ['Aminopeptidases', 'Animals', 'Cell Membrane', 'Kidney Cortex', 'Male', 'Microvilli', 'Protein Binding', 'Rats', 'Rats, Inbred Strains', 'beta 2-Microglobulin'] | 3,318,931 | [['D08.811.277.656.350.100'], ['B01.050'], ['A11.284.149'], ['A05.810.453.324'], ['A11.284.180.565'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D12.776.124.790.223.100', 'D12.776.377.715.182.100', 'D12.776.395.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plantar fasciitis treated with local steroid injection: comparison between sonographic and palpation guidance. | PURPOSE: To compare the effectiveness of sonographically guided and palpation-guided steroid injection for the treatment of proximal plantar fasciitis.PATIENTS AND METHODS: Twenty-five consecutive patients with unilateral proximal plantar fasciitis were recruited and randomly divided into a sonographically guided group... | ['Adult', 'Anti-Inflammatory Agents', 'Dexamethasone', 'Fasciitis, Plantar', 'Female', 'Humans', 'Injections, Intralesional', 'Male', 'Middle Aged', 'Pain Measurement', 'Physical Examination', 'Ultrasonography, Interventional'] | 16,353,228 | [['M01.060.116'], ['D27.505.954.158'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['C05.321.600', 'C05.360.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.430'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['E01.370.600'], ['E01.370.350.850.855', 'E04.502.890']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Conjugated linoleic acid determination in human milk by fast-gas chromatography. | An efficient direct method for measuring c9,t11- and t10,c12-conjugated linoleic acid (CLA) isomer content in human and rat milk was developed and validated using an RTX-2330 capillary column (40 m x 0.18 mm x 0.1 microm). In comparison with the commonly used 100 m x 0.25 mm x 0.20 microm columns, this new type of fast... | ['Animals', 'Chromatography, Gas', 'Humans', 'Linoleic Acids, Conjugated', 'Methylation', 'Milk', 'Milk, Human', 'Rats', 'Time Factors'] | 17,936,116 | [['B01.050'], ['E05.196.181.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.251.355.343.500.750'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sulfhydryl oxidation of mutants with cysteine in place of acidic residues in the lactose permease. | To examine further the role of charge-pair interactions in the structure and function of lactose permease, Asp237 (helix VII), Asp240 (helix VII), Glu126 (cytoplasmic loop IV/V), Glu269 (helix VIII), and Glu325 (helix X) were replaced individually with Cys in a functional mutant devoid of Cys residues. Each mutant was ... | ['Amino Acid Substitution', 'Aspartic Acid', 'Cysteine', 'Escherichia coli', 'Escherichia coli Proteins', 'Glutamic Acid', 'Membrane Transport Proteins', 'Monosaccharide Transport Proteins', 'Mutagenesis, Site-Directed', 'Oxidation-Reduction', 'Structure-Activity Relationship', 'Sulfhydryl Compounds', 'Sulfinic Acids',... | 9,609,715 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of digital rectal examination, transrectal ultrasonography, and multicoil magnetic resonance imaging for preoperative evaluation of prostate cancer. | OBJECTIVE: A prospective study was designed to compare the potentials of digital rectal examination (DRE), transrectal ultrasound (TRUS), and magnetic resonance imaging (MRI) using integrated endorectal and pelvic phased-array coils for preoperative estimation of tumor volume and local extent of prostate cancer.METHODS... | ['Aged', 'Biopsy, Needle', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Palpation', 'Predictive Value of Tests', 'Prospective Studies', 'Prostate', 'Prostatic Neoplasms', 'Sensitivity and Specificity', 'Ultrasonography'] | 9,286,643 | [['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.600.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ginkgolic acid promotes autophagy-dependent clearance of intracellular alpha-synuclein aggregates. | The accumulation of intracytoplasmic inclusion bodies (Lewy bodies) composed of aggregates of the alpha-synuclein (á-syn) protein is the principal pathological characteristic of Parkinson's disease (PD) and may lead to degeneration of dopaminergic neurons. To date there is no medication that can promote the efficient c... | ['Animals', 'Autophagosomes', 'Autophagy', 'Cell Line, Tumor', 'Cells, Cultured', 'Humans', 'Neurons', 'Neuroprotective Agents', 'Protein Aggregates', 'Rats', 'Rats, Wistar', 'Salicylates', 'Sumoylation', 'alpha-Synuclein'] | 31,654,699 | [['B01.050'], ['A11.284.430.214.190.875.190.700.500'], ['G04.011'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675', 'A11.671'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['D05.875'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.64... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Resection of multiple thymoma: a case report]. | A 74-year-old male, who had been treated for hypertension at the out-patient clinic, was admitted to our hospital because of an abnormal shadow on a chest radiograph. After diagnosis of thymoma by needle biopsy surgery was carried out on July 6, 1995, when an extended thymectomy along with removal of the entire tumor w... | ['Aged', 'Humans', 'Male', 'Thymectomy', 'Thymoma', 'Thymus Neoplasms'] | 9,396,265 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928.770'], ['C04.557.435.850', 'C04.588.894.949.500', 'C15.604.861.800'], ['C04.588.894.949', 'C15.604.861']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mitochondrial function in type I cells isolated from rabbit arterial chemoreceptors. | 1. In this, and the accompanying paper (Duchen & Biscoe, 1992), we test the hypothesis that the oxygen sensitivity of mitochondrial electron transport forms a basis for transduction in the carotid body, the primary peripheral arterial oxygen sensor. We here describe for isolated type I cells the changes in autofluoresc... | ['Animals', 'Calcium', 'Carotid Body', 'Cells, Cultured', 'Chemoreceptor Cells', 'Cyanides', 'Flavin-Adenine Dinucleotide', 'Fluorescence', 'Mitochondria', 'NADP', 'Oxygen Consumption', 'Rabbits'] | 1,432,706 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A08.675.650.915.500.600.150', 'A08.800.950.500.600.150', 'A11.671.650.915.500.600.150'], ['A11.251'], ['A08.675.650.915.500', 'A08.800.950.500', 'A11.671.650.915.500'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D03.633.100.733.315.650.249', 'D03... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treating the condemned to death. | Psychiatrists should refrain from treating mentally ill prisoners on death row in order to restore their "competency to be executed." Such "treatment" renders them double agents, in the service of the state as well as the prisoner. Participation in an act that will bring about a prisoner's death is expressly forbidden ... | ['Capital Punishment', 'Ethics, Medical', 'Humans', 'Mentally Ill Persons', 'National Socialism', 'Psychiatry', 'Trust', 'United States'] | 3,804,727 | [['I01.880.604.160'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.150.725'], ['I01.696.586'], ['F04.096.544', 'H02.403.690'], ['F01.829.401.825'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Single arterial trunk arising from the aortic arch. Evidence that the fifth branchial arch can persist as the definitive aortic arch. | A seven month old female having a single arterial trunk arising from the aortic arch is presented. The baby also had severe coarctation of the aorta and a patent ductus arteriosus. This anomaly cannot be explained by Edwards' embryonic double aortic arch model. However, it can be explained by persistence of the fifth b... | ['Aorta, Thoracic', 'Branchial Region', 'Child, Preschool', 'Female', 'Humans'] | 1,771,120 | [['A07.015.114.056.372'], ['A16.142'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Correlates of functional status, self-management, and developmental competence outcomes in adolescents with spina bifida. | Adolescents with spina bifida (SB), a congenital spinal cord impairment, are at high risk for negative outcomes. Even those with favorable cognitive status often fail to achieve independence, exhibiting poor functional and psychosocial outcomes. The purpose of this study was to examine the relationship between adaptati... | ['Adolescent', 'Adult', 'Attitude', 'Child', 'Decision Making', 'Female', 'Humans', 'Male', 'Self Care', 'Self Concept', 'Self Efficacy', 'Social Adjustment', 'Spinal Dysraphism', 'Surveys and Questionnaires'] | 14,626,030 | [['M01.060.057'], ['M01.060.116'], ['F01.100'], ['M01.060.406'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.900', 'I03.050.563', 'N02.421.784.680'], ['F01.752.747.792'], ['F01.752.747.792.700'], ['F01.145.813.621'], ['C10.500.680.800', 'C16.131.666.680.800'], ['E05.318.308.980', 'N05.71... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Overexpression of tumour-associated trypsin inhibitor (TATI) enhances tumour growth and is associated with portal vein invasion, early recurrence and a stage-independent prognostic factor of hepatocellular carcinoma. | Tumour-associated trypsin inhibitor (TATI) overexpresses in various tumours, but its clinicopathological significance in hepatocellular carcinoma (HCC) is unclear. Differential display analysis revealed expression of TATI in HCC. By RT-PCR in the linear range, TATI was found to be overexpressed in 176 of 258 unifocal p... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Disease Progression', 'Female', 'HeLa Cells', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Proteins', 'Neoplasm Recurrence, Local', 'Osteopontin', 'Portal Vein', 'Prognosis', 'Survival Analysis', 'Trypsin Inhibitor, Kazal Pancreat... | 17,267,202 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C23.550.291.656'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.0... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expanding the Coverage of the Metabolome with Nitrogen-Based NMR. | Isotopically labeling a metabolite and tracing its metabolic fate has provided invaluable insights about the role of metabolism in human diseases in addition to a variety of other issues. 13C-labeled metabolite tracers or unlabeled 1H-based NMR experiments are currently the most common application of NMR to metabolomic... | ['Acetates', 'Adenine', 'Ammonium Chloride', 'Arginine', 'Carbon Isotopes', 'Escherichia coli', 'Glutamine', 'Humans', 'Metabolome', 'Metabolomics', 'Molecular Structure', 'Nitrogen Isotopes', 'Nuclear Magnetic Resonance, Biomolecular', 'Ornithine', 'Staphylococcus aureus', 'Thiamine'] | 29,505,241 | [['D02.241.081.018', 'D10.251.400.045'], ['D03.633.100.759.138'], ['D01.210.450.150.050', 'D01.625.062.249'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D01.268.150.075', 'D01.496.123'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The prevalence of intestinal nematodes in cats and dogs from Lancashire, north-west England. | OBJECTIVES: To estimate prevalence of clinically-relevant intestinal nematodes in UK cats and dogs using the sensitive faecal analysis technique FLOTAC.METHODS: Faecal samples were collected from 171 domestic dogs and 131 domestic cats living in urban areas of Lancashire and examined for the ova of intestinal parasites... | ['Animals', 'Anthelmintics', 'Cat Diseases', 'Cats', 'Dog Diseases', 'Dogs', 'England', 'Female', 'Intestinal Diseases, Parasitic', 'Male', 'Nematode Infections', 'Parasite Egg Count', 'Strongylida', 'Toxocara canis', 'Urban Population'] | 27,071,856 | [['B01.050'], ['D27.505.954.122.250.075'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['Z01.542.363.300'], ['C01.610.432', 'C06.405.469.452'], ['C01.610.335.508'], ['E01.370.225.932.600', 'E05.200.932.600'], ['B01.050.500.500.294.400.968'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Secondary structure formations of conotoxin genes: a possible role in mediating variability. | Small venomous peptides called conotoxins produced by the predatory marine snail (genus Conus) present an interesting case for mutational studies. They have a high degree of amino acid variability among them yet they possess highly conserved structural elements that are defined by cysteine residues forming disulfide br... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Codon', 'Conotoxins', 'Conserved Sequence', 'DNA, Complementary', 'Molecular Sequence Data', 'Mutation', 'Nucleic Acid Conformation', 'Protein Structure, Secondary', 'Sequence Homology, Amino Acid', 'Sequence Homology, Nucleic Acid', 'Snails'] | 16,949,043 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D20.888.590.162', 'D23.946.580.590.162', 'D23.946.833.590.162'], ['G02.111.570.580'], ['D13.444.308.497.220', 'D13.444.600.223... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of a Functional Ruthenium(II) Complex that Can Act as a Photoluminescent and Electrochemiluminescent Dual-signaling Probe for Hypochlorous Acid. | A functional ruthenium(II) complex that can act as a probe for response to hypochlorous acid (HOCl) in aqueous media with photoluminescence (PL) and electrochemiluminescence (ECL) dual-signals, [Ru(bpy)2(DB-phen)](PF6)2 [bpy: 2,2'-bipyridine; DB-phen: 5-(2,4-dimethoxybenzylamino)-1,10-phenanthroline)], has been designe... | ["2,2'-Dipyridyl", 'Electrochemical Techniques', 'Fluorescent Dyes', 'Hypochlorous Acid', 'Light', 'Luminescent Measurements', 'Molecular Structure', 'Organometallic Compounds', 'Phenanthrolines', 'Ruthenium', 'Water'] | 25,962,768 | [['D03.383.725.220'], ['E05.301'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D01.029.260.365', 'D01.210.465', 'D01.339.431.311', 'D01.650.550.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.712.516'], ['G02.111.570', 'G02.466'], ['D02.691'], ['D03.633.300.669'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tamoxifen inhibits 5-lipoxygenase in human polymorphonuclear leucocytes. | Breast cancer patient survival is increased by tamoxifen, and we therefore need to understand how this drug exerts its effect. We describe a novel action of tamoxifen, the inhibition of LTB4 and 5-HETE production from [14C]-arachidonic acid by human polymorphonuclear leucocytes. | ['Arachidonate Lipoxygenases', 'Humans', 'Lipoxygenase Inhibitors', 'Neutrophils', 'Tamoxifen'] | 2,884,303 | [['D08.811.682.690.416.583.500', 'D12.776.556.579.374.568.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.389.480'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D02.455.426.559.389.150.700.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liver storage iron in normal population of Cuba. | One hundred sixty-one liver specimens from subjects who died acute traumatic deaths were studied. Of these, 127 came from male subjects and 34 from female subjects. The liver storage iron values of subjects in the persent study dying acutely from traumas and the differences found are in agreement with those expected ac... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Anemia, Hypochromic', 'Child', 'Child, Preschool', 'Cuba', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Iron', 'Liver', 'Male', 'Middle Aged', 'Nutritional Physiological Phenomena', 'Sex Factors'] | 7,355,774 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C15.378.071.196'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.084.900.225', 'Z01.639.880.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D01.268.556.412', 'D01.268.956.2... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Antigen-presenting cells transfected with Hsp65 messenger RNA fail to treat experimental tuberculosis. | In the last several years, the use of dendritic cells has been studied as a therapeutic strategy against tumors. Dendritic cells can be pulsed with peptides or full-length protein, or they can be transfected with DNA or RNA. However, comparative studies suggest that transfecting dendritic cells with messenger RNA (mRNA... | ['Animals', 'Antigen-Presenting Cells', 'Bacterial Proteins', 'Chaperonin 60', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mycobacterium tuberculosis', 'RNA, Messenger', 'Spleen', 'Transfection', 'Tuberculosis', 'Tuberculosis Vaccines'] | 22,983,180 | [['B01.050'], ['A11.066', 'A15.382.066'], ['D12.776.097'], ['D08.811.277.040.025.142.500.500', 'D12.776.580.216.210.590.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sound imaging of nocturnal animal calls in their natural habitat. | We present a novel method for imaging acoustic communication between nocturnal animals. Investigating the spatio-temporal calling behavior of nocturnal animals, e.g., frogs and crickets, has been difficult because of the need to distinguish many animals' calls in noisy environments without being able to see them. Our m... | ['Acoustics', 'Animals', 'Behavior, Animal', 'Circadian Rhythm', 'Ecosystem', 'Environment', 'Ethology', 'Ranidae', 'Sound', 'Species Specificity', 'Video Recording', 'Vocalization, Animal'] | 21,584,762 | [['H01.671.031'], ['B01.050'], ['F01.145.113'], ['G07.180.562.190'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275', 'N06.230'], ['F04.096.208'], ['B01.050.150.900.090.180.708'], ['G01.750.770.776'], ['G16.824'], ['L01.280.960'], ['F01.145.113.055.800']] | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Disorders of taste. | At least 2 million Americans suffer with chemosensory dysfunction or disorders of taste and smell. In addition to the obvious aesthetic deprivation, loss of taste may affect an individual's health and psychosocial situation. Most taste disorders are associated with antecedent upper respiratory infection, trauma, or all... | ['Humans', 'Taste Disorders', 'Zinc'] | 2,794,747 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.751.861', 'C23.888.592.763.861'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-idiotypic antibodies raised against anti-metenkephalin antibodies in rabbits. | Anti-idiotypic antibodies were raised in rabbits immunized against immunoglobulins purified from anti-metenkephalin antibody. The antibodies competed dose-dependently with metenkephalin in binding to anti-metenkephalin antibody on a solid phase metenkephalin enzyme-linked immunosorbent assay (ELISA). The titers of the ... | ['Animals', 'Antibodies', 'Antigen-Antibody Complex', 'Enkephalin, Methionine', 'Enzyme-Linked Immunosorbent Assay', 'Immunoglobulin G', 'Immunoglobulin Idiotypes', 'Rabbits', 'Receptors, Opioid'] | 2,828,978 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combining ECG Criteria for Left Ventricular Hypertrophy Improves Risk Prediction in Patients With Hypertension. | BACKGROUND: Patients with hypertension with ECG left ventricular hypertrophy (LVH) have higher cardiovascular morbidity and mortality, but single ECG criteria may underestimate risk. Whether continued presence or new development of ECG LVH by 2 criteria can further concentrate risk during blood pressure lowering is unc... | ['Aged', 'Antihypertensive Agents', 'Atenolol', 'Electrocardiography', 'Female', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Incidence', 'Losartan', 'Male', 'Risk Factors', 'Survival Rate', 'Treatment Outcome', 'United States'] | 29,151,037 | [['M01.060.116.100'], ['D27.505.954.411.162'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.280.195.400', 'C23.300.775.250.400'], ['E05.318.308.985.525.375', 'N01.224... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Value of urine sediment phenotyping in renal allograft recipients. | Leukocytes excreted in urine of renal transplant recipients were phenotyped and the results were correlated with their post-transplant course. The majority of excreted cells were monocytes, a phenomenon that bore no relationship to clinical status of the patients. T-lymphocyturia was associated with both acute rejectio... | ['Cell Count', 'Graft Rejection', 'Humans', 'Kidney Transplantation', 'Leukocytes, Mononuclear', 'Phenotype', 'Predictive Value of Tests', 'T-Lymphocytes', 'Urinary Tract Infections', 'Urine'] | 8,010,879 | [['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['G05.695'], ['E05.318.370.800.650', 'N05.715.360.325.700.640... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparing predictability between eyes after bilateral laser in situ keratomileusis: a theoretical analysis of simultaneous versus sequential procedures. | OBJECTIVE: To compare the predictability of laser in situ keratomileusis (LASIK) between eyes of individuals to determine whether the refractive result of the first eye is useful in improving fellow eye outcomes.DESIGN: Single-center case series.PARTICIPANTS: One surgeon and 196 eyes of 98 patients.INTERVENTION: All pa... | ['Adult', 'Cohort Studies', 'Cornea', 'Corneal Transplantation', 'Female', 'Follow-Up Studies', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Models, Theoretical', 'Myopia', 'Prognosis', 'Refraction, Ocular', 'Surgical Flaps', 'Visual Acuity'] | 10,485,535 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A09.371.060.217'], ['E02.095.147.725.225', 'E04.540.825.374', 'E04.936.580.225'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
15N-1H scalar coupling perturbation: an additional probe for measuring structural changes due to ligand binding. | Chemical shift perturbation mapping of backbone amides is one of the most widely employed techniques in biomolecular NMR, providing residue-by-residue information on interaction interfaces, ligand binding, and chemical modification sites, even for samples where poor solubility, short lifetime, or large size precludes m... | ['Amides', 'Binding Sites', 'Ligands', 'Models, Molecular', 'Molecular Structure', 'Nitrogen Isotopes', 'Nuclear Magnetic Resonance, Biomolecular', 'Protons'] | 19,580,276 | [['D02.065'], ['G02.111.570.120'], ['D27.720.470.480'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D01.268.604.500', 'D01.362.625.500', 'D01.496.586'], ['E05.196.867.519.550'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pedigree analysis for quantitative traits: variance components without matrix inversion. | Recent developments in the animal breeding literature facilitate estimation of the variance components in quantitative genetic models. However, computation remains intensive, and many of the procedures are restricted to specialized designs and models, unsuited to data arising from studies of natural populations. We dev... | ['Algorithms', 'Analysis of Variance', 'Animal Husbandry', 'Animals', 'Biometry', 'Crosses, Genetic', 'Female', 'Male', 'Models, Genetic', 'Models, Statistical', 'Pedigree'] | 2,364,130 | [['G17.035', 'L01.224.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['J01.040.090'], ['B01.050'], ['E05.318.740.225', 'N06.850.505.200'], ['E05.393.281'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.393.673']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Protein cryoprotective activity of a cytosolic small heat shock protein that accumulates constitutively in chestnut stems and is up-regulated by low and high temperatures. | Heat shock, and other stresses that cause protein misfolding and aggregation, trigger the accumulation of heat shock proteins (HSPs) in virtually all organisms. Among the HSPs of higher plants, those belonging to the small HSP (sHSP) family remain the least characterized in functional terms. We analyzed the occurrence ... | ['Acclimatization', 'Amino Acid Sequence', 'Cloning, Molecular', 'DNA, Complementary', 'Fagaceae', 'Gene Expression Regulation, Plant', 'Heat-Shock Proteins', 'Molecular Sequence Data', 'Plant Proteins', 'Plant Stems', 'RNA, Messenger', 'Sequence Analysis, DNA', 'Temperature'] | 15,064,380 | [['G07.025.133', 'G16.012.500.133'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.650.940.800.575.912.250.859.750.300'], ['G05.308.375'], ['D12.776.580.216'], ['L01.453.245.667'], ['D12.776.765'], ['A18.024.937'], ['D13... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Four novel cases of permanent neonatal diabetes mellitus caused by homozygous mutations in the glucokinase gene. | Permanent neonatal diabetes mellitus (PNDM) caused by homozygous mutations in the glucokinase gene (GCK) is rare and only eight homozygous GCK mutations have been reported so far. Heterozygous GCK mutations cause maturity-onset diabetes of the young (MODY). We report four patients with growth retardation from two separ... | ['Codon, Nonsense', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Glucokinase', 'Homozygote', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Mutation, Missense', 'Pedigree', 'Siblings'] | 21,518,409 | [['D13.444.735.544.355.250.235', 'G05.360.335.355.250.235', 'G05.365.590.195'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['D08.811.913.696.620.250'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['G05.365.590.65... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Changing nursing practice through a nursing journal club. | As hospitals seek to promote evidence-based nursing practice and improve the quality of bedside nursing care, formation of a nursing journal club can be one strategy to accomplish both goals. | ['Clinical Competence', 'Education, Nursing, Continuing', 'Evidence-Based Medicine', 'Humans', 'Periodicals as Topic', 'Quality of Health Care'] | 16,447,830 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.212.450', 'I02.358.462.399'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.829.678'], ['N04.761', 'N05.715']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Lean Mass and Fat Mass as Mediators of the Relationship Between Physical Activity and Bone Mineral Density in Postmenopausal Women. | BACKGROUND: The relationship between physical activity (PA) and bone health is well known, but the role of lean mass (LM) and fat mass (FM) in this relationship remains uncertain. Therefore, the aim of this study was to examine the mediating effect of LM and FM on the relationship between PA and bone mineral density (B... | ['Absorptiometry, Photon', 'Aged', 'Asian Continental Ancestry Group', 'Body Composition', 'Body Mass Index', 'Bone Density', 'China', 'Cross-Sectional Studies', 'Exercise', 'Female', 'Humans', 'Middle Aged', 'Obesity', 'Postmenopause', 'Thinness'] | 28,437,220 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116.100'], ['M01.686.508.200'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Testing patients with non-specific symptoms for antibodies against Borrelia burgdorferi sensu lato does not provide useful clinical information about their aetiology. | The aim of this study was to determine whether patients with antibodies against Borrelia burgdorferi sensu lato or who report a history of erythema migrans (EM) or tick bite are more likely to have non-specific symptoms such as musculoskeletal pain, fatigue, sensory disorder, and headache. The study group comprised 423... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Bacterial', 'Borrelia burgdorferi', 'Child', 'DNA, Bacterial', 'Erythema Chronicum Migrans', 'Fatigue', 'Female', 'Headache', 'Humans', 'Male', 'Middle Aged', 'Musculoskeletal Pain', 'Sensation Disorders', 'Tick Bites', 'Young Adult'] | 26,321,669 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['M01.060.406'], ['D13.444.308.212'], ['C01.150.252.400.536.400', 'C01.150.252.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Experiencing Body Worlds: voyeurism, education, or enlightenment? | Until the advent of plastinated cadavers, few outside the medical professions have had firsthand experience with human corpses. Such opportunities are now available at the Body Worlds exhibits of Gunther von Hagens. After an overview of these exhibits, we explore visitor responses as revealed in comment books available... | ['Anatomy, Artistic', 'Humans', 'Medical Illustration', 'United States', 'Voyeurism'] | 17,876,528 | [['H01.158.100.091', 'K01.093.410.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.385', 'J01.897.280.500.480', 'K01.093.410', 'L01.178.820.090.480'], ['Z01.107.567.875'], ['F03.657.900']] | ['Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 |
Effect of butylated hydroxytoluene on alpha-tocopherol content in liver and adipose tissue of rats. | Female rats were fed an antioxidant supplemented diet containing butylated hydroxytoluene (BHT; 0.5% and 1.0%) with or without vitamin E acetate (0.4%) for 4 weeks, after which the contents of BHT and alpha-tocopherol in the liver and abdominal adipose tissue were analysed. The body weight gain was similar in all group... | ['Adipose Tissue', 'Analysis of Variance', 'Animals', 'Antioxidants', 'Butylated Hydroxytoluene', 'Cytochrome P-450 Enzyme System', 'Female', 'Frozen Sections', 'Liver', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species', 'Spectrophotometry, Ultraviolet', 'Vitamin E'] | 8,914,617 | [['A10.165.114'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.657.239.216'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['E01.370.225.500.620.530.160.260', 'E01.370.225.750.60... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Oropouche virus is detected in peripheral blood leukocytes from patients. | Oropouche virus (OROV) is a frequent cause of arboviral febrile disease in the Amazon. The present report describes studies done in two patients, one of them; the first OROV human case acquired outside of the Amazon, which have revealed for the first time the presence of OROV in peripheral blood leukocytes. This novel ... | ['Adolescent', 'Animals', 'Bunyaviridae Infections', 'Female', 'Humans', 'Leukocytes', 'Male', 'Middle Aged', 'Orthobunyavirus'] | 27,787,907 | [['M01.060.057'], ['B01.050'], ['C01.925.782.147'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['M01.060.116.630'], ['B04.820.480.750.640']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Peritoneal dialysis in Hungary. | In 1991 the technical conditions and the number of patients receiving peritoneal dialysis were surveyed in the Hungarian nephrology and dialysing units. Not only the number of patients with chronic uraemia (undergoing dialysis + transplantation) is lower in this country as compared to the European average (106 and 236 ... | ['Data Collection', 'Dialysis Solutions', 'Disinfectants', 'Humans', 'Hungary', 'Peritoneal Dialysis', 'Peritoneal Dialysis, Continuous Ambulatory', 'Uremia'] | 1,459,835 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['D26.776.708.322', 'D27.505.954.578.483', 'D27.720.752.483'], ['D27.505.954.122.425', 'D27.720.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['E02.870.300.650', 'E02.912.800.650'], ['E02.760.106.500', 'E02.870.300.650... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
[Effects of roncoleukin on immune parameters and mixed anxiety/depression state induced by chronic social defeat stress in male mice]. | UNLABELLED: Chronic social defeat stress leads to the development of mixed anxiety-depression state, which accompanied by immune deficiency in male mice. Paper aimed to study effects of ronkoleukin on the parameters of cellular immunity in the thymus and spleen and psychoemotional state in these animals.METHODS: Mixed ... | ['Animals', 'Antidepressive Agents', 'Anxiety', 'Behavior, Animal', 'Depression', 'Immunity, Cellular', 'Immunity, Innate', 'Immunocompromised Host', 'Immunologic Factors', 'Immunophenotyping', 'Injections, Intraperitoneal', 'Interleukin-2', 'Lymphocyte Count', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Spleen', 'Stress, P... | 25,470,897 | [['B01.050'], ['D27.505.954.427.700.122'], ['F01.470.132'], ['F01.145.113'], ['F01.145.126.350'], ['G12.450.050.400'], ['G12.450.564'], ['G12.470'], ['D27.505.696.477'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['E02.319.267.530.490'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.77... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organochlorine and heavy metal residues in black duck eggs from the Atlantic Flyway, 1978. | Black duck (Anas rubripes) eggs were collected during 1978 in the Atlantic Flyway. One egg from each of 49 clutches was analyzed for organochlorine compounds and mercury. DDE was detected in 39 eggs, ranging from 0.09 ppm to 3.4 ppm, wet weight. DDE residues were highest in eggs from Delaware, where the mean DDE level ... | ['Animals', 'Arsenic', 'Chromium', 'Copper', 'Ducks', 'Egg Shell', 'Eggs', 'Hydrocarbons, Chlorinated', 'Insecticides', 'Mercury', 'Metals', 'Time Factors', 'United States'] | 7,232,104 | [['B01.050'], ['D01.268.513.249'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['A13.316'], ['G07.203.300.470', 'J02.500.470'], ['D02.455.526.439'], ['D27.720.031.700.491', 'D27.888.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
[Metabolic features of continuous cell lines of mosquitoes]. | The metabolism of a continuous Ae. albopictus cell line (clone C6/36) was studied relative to the consumption of an environmental component by mammalian cells of the continuous lines Vero(B) and BNK-21 under steady-state cultivation conditions. The Ae. albopictus cells were found to utilize the amino acid glycine and o... | ['Aedes', 'Animals', 'Cell Culture Techniques', 'Cell Line', 'Glycine', 'Glycolysis', 'Lactic Acid'] | 19,566,064 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210'], ['D12.125.481'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['D02.241.511.459.450']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intramuscular innervation of the human soleus muscle: a 3D model. | The purpose of this study was to document the neural distribution patterns within the human soleus muscle using 3D computer modelling. Through serial dissection, pinning, and digitization, nerve distribution and muscle volume of a human cadaveric soleus muscle were documented and a detailed 3D computer model of neural ... | ['Computer Simulation', 'Humans', 'Imaging, Three-Dimensional', 'Models, Anatomic', 'Muscle, Skeletal', 'Tibial Nerve'] | 12,903,058 | [['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['A02.633.567', 'A10.690.552.500'], ['A08.800.800.720.450.760.820']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Healing current through a goiter. The life, work and after effects of the magic healer Bruno Gr?ning]. | During the years between 1949 and 1959 the wonder healer Bruno Gr?ning (1906-1959) gripped the public and medical interest in Germany. He explained to be a descent of Jesus Christ, sending "healing waves" to end diseases and made a lot of money. Finally he was found guilty in letting a persuaded fan dying and was convi... | ['Famous Persons', 'Germany', 'Goiter', 'History, 20th Century', 'Humans', 'Male', 'Mental Healing', 'National Socialism', 'Quackery', 'Religion and Medicine'] | 18,693,642 | [['K01.517.211.506', 'M01.228'], ['Z01.542.315'], ['C19.874.283'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.500', 'E02.190.901.500'], ['I01.696.586'], ['I01.880.735.728'], ['K01.844.619']] | ['Humanities [K]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Aureobasidins as new inhibitors of P-glycoprotein in multidrug resistant tumor cells. | Cyclic depsipeptide antibiotic aureobasidin A (AbA) and its analogs were tested for the inhibitory activity of P-glycoprotein in multidrug resistant cancer cells as well as for the antifungal activity. Some analogs with lower antifungal activity than AbA showed higher inhibition of P-glycoproteins indicating difference... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'ATP-Binding Cassette Transporters', 'Antifungal Agents', 'Depsipeptides', 'Humans', 'Multidrug Resistance-Associated Proteins', 'Peptides, Cyclic', 'Structure-Activity Relationship', 'Tumor Cells, Cultured', 'Vincristine'] | 9,589,072 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation of in vivo cow control blood samples for cadmium analysis. | Quality control is essential for any analysis in the laboratory. The objective of this study was to prepare in vivo cow control blood samples. The experiment was performed by feeding cows with a single dose of cadmium in the form of cadmium chloride, withdrawing the blood at an appropriate time to get the highest level... | ['Administration, Oral', 'Analysis of Variance', 'Animals', 'Cadmium Chloride', 'Cattle', 'Male', 'Quality Control'] | 17,120,977 | [['E02.319.267.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D01.142.175', 'D01.210.450.150.125'], ['B01.050.150.900.649.313.500.380.271'], ['J01.897.608']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Characterization, in vitro and in vivo studies on primaquine diphosphate liposomes. | In this study, several Primaquine diphosphate (PQ) liposomal formulations containing phospholipid, charge inducer and with or without cholesterol in molar ratios of 7:1:(2) and 10:1:(4) were investigated. Gel state (DPPC:CHEMS:CHOL and PL-100H:CHEMS:CHOL) and liquid-crystalline state (PL-100:CHEMS:CHOL and PL-90G:CHEMS... | ['Animals', 'Antimalarials', 'Drug Carriers', 'Drug Compounding', 'Isotope Labeling', 'Kinetics', 'Liposomes', 'Magnetic Resonance Spectroscopy', 'Mice', 'Particle Size', 'Primaquine', 'Quality Control', 'Technetium', 'Tissue Distribution'] | 8,544,091 | [['B01.050'], ['D27.505.954.122.250.100.085'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.270'], ['E05.522'], ['G01.374.661', 'G02.111.490'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E05.196.867.519'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.712'], ['D03.633.100.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Does maintaining or changing shift types affect BMI? A longitudinal study. | OBJECTIVES: To examine the impact of maintaining or changing shift work status on body mass index (BMI) among female nurses and midwives.METHODS: A longitudinal study. Measurements included day work maintainers, shift work maintainers, day to shift changers and shift to day changers, changes in BMI, and potential confo... | ['Adult', 'Aged', 'Alcohol Drinking', 'Body Mass Index', 'Chi-Square Distribution', 'Diet', 'Female', 'Humans', 'Life Style', 'Longitudinal Studies', 'Middle Aged', 'Midwifery', 'Motor Activity', 'Multivariate Analysis', 'Nursing', 'Personnel Staffing and Scheduling', 'Smoking', 'Work Schedule Tolerance', 'Young Adult'... | 22,576,459 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.317.269'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Research in psychoanalytic therapy 1930-1990]. | The author provides a survey of three phases of psychoanalytic therapy research, each one is being characterized by its most important representatives and their contributions. The first phase (1930-1970) sought in essence to justify, i.e. to prove, that analytical therapies are useful. The second phase (1960-1980) was ... | ['History, 20th Century', 'Humans', 'Psychoanalysis', 'Psychoanalytic Theory', 'Psychoanalytic Therapy', 'Research', 'Treatment Outcome'] | 1,581,701 | [['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.544.779'], ['F02.739.794'], ['F04.754.709'], ['H01.770.644'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Analysis of mannans of two relatively avirulent mutant strains of Candida albicans. | We previously reported the isolation of two cerulenin-resistant mutant strains of Candida albicans 4918 that differ in adherence properties and are less virulent than the parental strain. In addition, biochemical characterization demonstrated significant differences in both protein and polysaccharide composition of cel... | ['Acetylation', 'Candida albicans', 'Chromatography, High Pressure Liquid', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Mannans', 'Mannose', 'Mutation', 'Virulence'] | 2,643,567 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['E05.196.181.400.300'], ['G02.300'], ['G02.380'], ['E05.196.867.519'], ['D09.698.550'], ['D09.947.875.359.588'], ['G05.365.590'], ['G06.930']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurobehavioral functioning of persons with Parkinson's disease. | This study examines the neurobehavioral functioning of persons with Parkinson's disease (PD) using the Neuropsychology Behavior and Affect Profile (NBAP), a self-report version of the Neurobehavioral Rating Scale (NRS-Revised), and the Dysexecutive Questionnaire (DEX). In the absence of existing data, the psychometric ... | ['Case-Control Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Parkinson Disease', 'Personality', 'Psychometrics', 'Severity of Illness Index', 'Social Behavior', 'Surveys and Questionnaires', 'Task Performance and Analysis'] | 12,788,680 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['F01.752'], ['F04.711.780'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phocine distemper in a harp seal (Phoca groenlandica) from the Gulf of St. Lawrence, Canada. | The first case of phocine distemper in a seal from Canadian waters and the first case of clinical phocine distemper in a harp seal, Phoca groenlandica, is reported. A two-month-old female harp seal stranded on Prince Edward Island in May 1991. Significant clinical findings were lethargy and severe conjunctivitis. Pulmo... | ['Animals', 'Astrocytes', 'Cerebral Cortex', 'Female', 'Inclusion Bodies, Viral', 'Lung', 'Neurons', 'Paramyxoviridae', 'Prince Edward Island', 'Respirovirus Infections', 'Seals, Earless', 'Urinary Bladder'] | 8,445,769 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211.200.885.287.500'], ['A11.284.420.390', 'G06.920.400'], ['A04.411'], ['A08.675', 'A11.671'], ['B04.820.480.937.600'], ['Z01.107.567.176.732', 'Z01.639.820'], ['C01.925.782.580.600.600'], ['B01.050.150.900.649.313.750.250.700'], ['A05.810.890']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Baculovirus-mediated immediate-early gene expression and nuclear reorganization in human cells. | Baculovirus, Autographa californica multiple nucleopolyhedrovirus (AcMNPV), has the ability to transduce mammalian cell lines without replication. The general objective of this study was to detect the transcription and expression of viral immediate-early genes in human cells and to examine the interactions between vira... | ['Animals', 'Anthraquinones', 'Capsid', 'Cell Line', 'Cell Nucleus', 'Chromatin Assembly and Disassembly', 'Gene Expression', 'Genes, Immediate-Early', 'Histones', 'Humans', 'Mice', 'Microscopy, Confocal', 'Microscopy, Fluorescence', 'Nucleopolyhedroviruses', 'Viral Proteins'] | 18,042,259 | [['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['A21.249.500.250'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.400.095', 'G05.213.095', 'G05.308.095'], ['G05.297'], ['G05.360.340.024.340.330', 'G05.360.340.024.340.364.875.345', 'G05.360.340.358.024.875.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuroprotective Effect of Lutein on NMDA-Induced Retinal Ganglion Cell Injury in Rat Retina. | Lutein injection is a possible therapeutic approach for retinal diseases, but the molecular mechanism of its neuroprotective effect remains to be elucidated. The aim of this study was to investigate its protective effects in retinal ganglion cells (RGCs) against N-methyl-D-aspartate (NMDA)-induced retinal damage in viv... | ['Animals', 'Apoptosis', 'Behavior, Animal', 'Blotting, Western', 'Caspase 3', 'Cell Count', 'Cytochromes c', 'Electroretinography', 'Female', 'Glycogen Synthase Kinase 3 beta', 'Intravitreal Injections', 'Lutein', 'Mitogen-Activated Protein Kinases', 'N-Methylaspartate', 'Neuroprotective Agents', 'Photic Stimulation',... | 26,119,305 | [['B01.050'], ['G04.146.954.035'], ['F01.145.113'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['E01.370.225.500.195', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal response to atrial natriuretic factor in conscious dogs with caval constriction. | Constriction of the thoracic inferior vena cava to decrease venous return and atrial filling markedly elevates plasma renin activity (PRA) and plasma aldosterone concentration (PAC) and produces chronic sodium retention and ascites in the dog. Infusion of a synthetic atrial natriuretic factor into conscious dogs with c... | ['Aldosterone', 'Animals', 'Atrial Natriuretic Factor', 'Blood Pressure', 'Cardiomyopathies', 'Consciousness', 'Constriction, Pathologic', 'Creatine', 'Dogs', 'Female', 'Heart Rate', 'Kidney', 'Muscle Proteins', 'Potassium', 'Renin', 'Sodium', 'Vena Cava, Inferior', 'p-Aminohippuric Acid'] | 3,157,329 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.238'], ['F02.463.188.409', 'F02.830.233'], ['C23.300.287'], ['D02.078.370.280', 'D12.125.373'], ['B01.050.150.900.649.313.750.250.216.200'], ['E... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Demographic history of Canary Islands male gene-pool: replacement of native lineages by European. | BACKGROUND: The origin and prevalence of the prehispanic settlers of the Canary Islands has attracted great multidisciplinary interest. However, direct ancient DNA genetic studies on indigenous and historical 17th-18th century remains, using mitochondrial DNA as a female marker, have only recently been possible. In the... | ['African Continental Ancestry Group', 'Chromosomes, Human, Y', 'DNA, Mitochondrial', 'European Continental Ancestry Group', 'Evolution, Molecular', 'Female', 'Gene Pool', 'Genetics, Population', 'Humans', 'Male', 'Polymorphism, Restriction Fragment Length', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA', ... | 19,650,893 | [['M01.686.508.100'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['D13.444.308.283.225'], ['M01.686.508.400'], ['G05.045.250', 'G16.075.250'], ['G05.342'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.5... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
A decision analysis of mandatory compared with voluntary HIV testing in pregnant women. | BACKGROUND: The benefit of antiretroviral therapy in reducing maternal-fetal transmission of HIV during pregnancy has caused a public policy debate about the relative benefits of mandatory HIV screening and voluntary HIV screening in pregnant women.OBJECTIVE: To evaluate the benefits and risks of mandatory compared wit... | ['Anti-HIV Agents', 'Decision Trees', 'Female', 'HIV Infections', 'Health Policy', 'Humans', 'Infectious Disease Transmission, Vertical', 'Mandatory Testing', 'Patient Acceptance of Health Care', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Pregnant Women', 'Prenatal Care', 'Prevalence', 'Risk Assessment', 'Sen... | 9,556,471 | [['D27.505.954.122.388.077.088'], ['G17.162.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.875'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Nested allosteric interaction in tarantula hemocyanin revealed through the binding of oxygen and carbon monoxide. | We have examined the competitive binding of oxygen and carbon monoxide to the multisubunit hemocyanin of the tarantula Eurypelma californicum. Employment of high-precision thin-layer methods has enabled detailed characterization of the pure oxygen and pure carbon monoxide binding curves, as well as binding curves perfo... | ['Allosteric Site', 'Animals', 'Arthropods', 'Binding, Competitive', 'Carbon Monoxide', 'Hemocyanins', 'Models, Chemical', 'Oxygen'] | 3,196,690 | [['G02.111.570.120.147'], ['B01.050'], ['B01.050.500.131'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['D12.776.093.375', 'D12.776.556.462', 'D23.767.482'], ['E05.599.495'], ['D01.268.185.550', 'D01.362.670']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison between human and automated electrocardiographic waveform measurements for calculating the Anderson-Wilkins acuteness score in patients with acute myocardial infarction. | The Anderson-Wilkins (AW) electrocardiographic (ECG) acuteness score complements time from pain onset in prognostic stratification of patients with acute myocardial infarction (AMI). However, for the AW acuteness score to be of practical use in the acute situation, it must be an integral component of a commercial autom... | ['Diagnosis, Computer-Assisted', 'Electrocardiography', 'Humans', 'Myocardial Infarction'] | 15,892,017 | [['E01.158', 'L01.313.500.750.100.158'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
New ways for the standardization of autoantibody assays: chimeric monoclonal antibodies. | Recombinant production of human autoantigens and new assay methodologies have created new opportunities for the detection of autoantibodies in autoimmune disease situations. However, the standardization of test results remains unsatisfactory which can be traced to supply and batch variation problems of the patient sera... | ['Animals', 'Antibodies, Monoclonal', 'Autoantibodies', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoglobulin G', 'Mice', 'Mice, Transgenic', 'Recombinant Fusion Proteins', 'Reference Standards'] | 11,712,698 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lung and dermal vascular injury produced by preformed immune complexes. | Tissue injury was studied in rat lung and in the dermal vasculature after the injection of preformed, heterologous immune complexes. In lung, these complexes induced an acute, hemorrhagic alveolitis with large numbers of neutrophils. There were marked increases in permeability and extensive intrapulmonary hemorrhage. S... | ['Animals', 'Antigen-Antibody Complex', 'Cell Membrane Permeability', 'Lung', 'Lymphocyte Depletion', 'Male', 'Neutrophils', 'Rats', 'Serum Albumin, Bovine', 'Skin', 'Time Factors'] | 629,488 | [['B01.050'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['G03.143.335', 'G04.175'], ['A04.411'], ['E02.095.465.425.450.521', 'E05.478.610.570'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Independent predictors of survival in patients with incurable malignant gastric outlet obstruction: a multicenter prospective observational study. | OBJECTIVE: Gastric outlet obstruction (GOO) is one of the late complications of a variety of malignancies. Palliation of symptoms of obstruction rather than cure is the primary aim of treatment in affected patients. Thus far prognostic information on life expectancy is lacking in these patients although it can be of im... | ['Adult', 'Aged', 'Aged, 80 and over', 'Analgesics, Opioid', 'Analysis of Variance', 'Female', 'Gastric Outlet Obstruction', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasms', 'Netherlands', 'Pain Measurement', 'Palliative Care', 'Predictive Value of Tests', 'Prognosis', 'Pr... | 20,459,356 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C06.405.748.340'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A facile synthesis of pyridazinone derivatives under ultrasonic irradiation. | A new, efficient and general method for preparation of N-substituted-pyridazinones using ultrasound irradiation is reported. Under ultrasound the reaction time decreases substantially, the yields are high and the reaction conditions are mild. It was noticed that substituents at the 3-(6)-position of pyridazone heterocy... | ['Molecular Structure', 'Pyridazines', 'Temperature', 'Ultrasonics'] | 19,121,972 | [['G02.111.570', 'G02.466'], ['D03.383.710'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['H01.671.031.849']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro insertion and assembly of outer membrane protein PhoE of Escherichia coli K-12 into the outer membrane. Role of Triton X-100. | The assembly of the in vitro synthesized outer membrane protein PhoE into purified outer membranes was investigated. The assembly appeared to be strongly stimulated by the presence of low amounts of Triton X-100 (optimal 0.08%, w/v). The role of Triton X-100 in the in vitro system was further examined. Pretreating oute... | ['Cell Membrane', 'Escherichia coli', 'Escherichia coli Proteins', 'Lipopolysaccharides', 'Mutation', 'Octoxynol', 'Porins'] | 8,662,743 | [['A11.284.149'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['G05.365.590'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.637.051.720.741.610'], ['D12.776.157.530.400... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Interferon-gamma enhances susceptibility of cervical cancer cells to lysis by tumor-specific cytotoxic T cells. | Recently we have demonstrated that tumor-specific cytotoxic T lymphocytes (CTLs) can be activated by cervical carcinoma cells expressing the costimulatory molecule CD80, which may be used as a therapeutic vaccine for patients with cervical cancer. For activated CTLs to be effective, appropriate amounts of MHC class I e... | ['B7-1 Antigen', 'CD58 Antigens', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Intercellular Adhesion Molecule-1', 'Interferon-gamma', 'Major Histocompatibility Complex', 'T-Lymphocytes, Cytotoxic', 'Tumor Cells, Cultured', 'Up-Regulation', 'Uterine Cervical Neoplasms'] | 9,159,336 | [['D12.776.467.150.100', 'D12.776.543.095.100', 'D23.050.301.285.100', 'D23.529.168.100'], ['D12.776.395.550.034', 'D12.776.543.550.158'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.200.450', 'D12.776.543.550.200.450', 'D23.050.301.350.450'], ['D12.644.276.374.440.893', 'D12.644... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human plasma dynamically quenches the fluorescein at the initial point of oxygen radical absorption capacity (ORAC) assay. | OBJECTIVE: Oxygen radical absorbance capacity (ORAC) assay measures the quenching of fluorescent probe by peroxyl radicals. Antioxidants present in biological systems block the quenching of fluorescence probe. We experienced the dynamic quenching of fluorescein, the fluorescence probe used in ORAC assay by the human pl... | ['Antioxidants', 'Fluorescein', 'Fluorescence', 'Fluorescent Dyes', 'Humans', 'Oxygen Radical Absorbance Capacity', 'Peroxides', 'Plasma'] | 31,843,018 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.657'], ['D01.248.497.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle. | Coronin 1C (synonyms: coronin-3, CRN2), a WD40 repeat-containing protein involved in cellular actin dynamics, is ubiquitously expressed in human tissues. Here, we report on the identification and functional characterization of two novel coronin 1C isoforms, referred to as CRN2i2 and CRN2i3, which also associate with F-... | ['Actins', 'Amino Acid Sequence', 'Base Sequence', 'Binding Sites', 'Cell Line', 'Chromatin Immunoprecipitation', 'Computational Biology', 'Humans', 'Immunohistochemistry', 'Microfilament Proteins', 'Molecular Sequence Data', 'Muscle, Skeletal', 'Myofibrils', 'Neuromuscular Junction', 'Promoter Regions, Genetic', 'Prot... | 19,651,142 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251.210'], ['E05.393.170', 'E05.478.605.160'], ['H01.158.273.180', 'L01.313.124'], ['B01.050.150.900.649.313.988.400.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Photographic capture-recapture sampling for assessing populations of the Indian gliding lizard Draco dussumieri. | The usage of invasive tagging methods to assess lizard populations has often been criticised, due to the potential negative effects of marking, which possibly cause increased mortality or altered behaviour. The development of safe, less invasive techniques is essential for improved ecological study and conservation of ... | ['Animals', 'Data Collection', 'India', 'Lizards', 'Photography', 'Population Density'] | 23,418,477 | [['B01.050'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.252.245.393'], ['B01.050.150.900.833.393'], ['E01.370.350.600', 'E05.712'], ['N01.224.600', 'N06.850.505.400.600']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Naphthalene-induced cataract model in rats: A comparative study between slit and retroillumination images, biochemical changes and naphthalene dose and duration. | PURPOSE: The purpose of the study was to compare different methods of photographic evaluation of cataract formation in rats in response to different regimes of naphthalene treatment. Furthermore, we intended to study the relationship between cataract extension and biochemical parameters.METHODS: Brown Norway rats were ... | ['Animals', 'Cataract', 'Cations', 'Crystallins', 'Diagnostic Imaging', 'Dose-Response Relationship, Drug', 'Female', 'Lens, Crystalline', 'Naphthalenes', 'Rats', 'Rats, Inbred BN', 'Time Factors'] | 10,520,218 | [['B01.050'], ['C11.510.245'], ['D01.248.497.300'], ['D12.776.306.366'], ['E01.370.350'], ['G07.690.773.875', 'G07.690.936.500'], ['A09.371.060.500'], ['D02.455.426.559.847.638', 'D04.615.638'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.110', 'B01.050.150.900.649.313.992.635.505.700.400.110... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multi-exposure and clustering of adverse childhood experiences, socioeconomic differences and psychotropic medication in young adults. | PURPOSE: Stressful childhood experiences have negative long-term health consequences. The present study examines the association between adverse childhood experiences, socioeconomic position, and risk of psychotropic medication in young adulthood.METHODS: This register-based cohort study comprises the birth cohorts bet... | ['Child', 'Child Abuse', 'Cluster Analysis', 'Educational Status', 'Female', 'Humans', 'Male', 'Prevalence', 'Psychotropic Drugs', 'Risk Factors', 'Socioeconomic Factors', 'Sweden', 'Young Adult'] | 23,341,951 | [['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'],... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Titanium Mesh Nasal Repair without Nasal Lining. | The objective of this study was to describe outcomes for patients who underwent titanium mesh reconstruction of full-thickness nasal defects without internal lining repair. This is a retrospective cohort study. Patients with through-and-through nasal defects were identified at a single academic institution between 2008... | ['Aged', 'Aged, 80 and over', 'Blood Loss, Surgical', 'Female', 'Follow-Up Studies', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Nasal Mucosa', 'Nose', 'Nose Deformities, Acquired', 'Nose Neoplasms', 'Operative Time', 'Postoperative Complications', 'Radiotherapy', 'Retrospective Studies', 'Rhinoplasty', 'Surgic... | 28,226,380 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.414.300', 'C23.550.505.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['A04.531.520', 'A04.760.600... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A concept for all the family. Family centred care: a concept analysis. | Family centred care is now perceived as fundamental to meeting hospitalised children's physical and emotional needs. It is important, however, that nurses fully understand the concept or it may be implemented more with the intention of meeting ward goals than family needs. | ['Family', 'Humans', 'Models, Nursing', 'Nursing Theory', 'Patient Participation', 'Pediatric Nursing'] | 8,367,510 | [['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.645'], ['H02.478.408'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.360.300', 'N05.300.150.800.500.620'], ['H02.478.676.631', 'N02.421.533.691']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Interferon-gamma production and HLA-DR expression in patients with retinitis pigmentosa. | Other investigators have reported deficient production of interferon-gamma (IFN-gamma) and reduced expression of class II major histocompatibility (HLA-DR) antigens on monocytes from patients with retinitis pigmentosa (RP). Our previous investigation did not demonstrate deficient IFN-gamma production by lymphocytes fro... | ['Adult', 'Female', 'Genes, Dominant', 'Genes, Recessive', 'HLA-D Antigens', 'HLA-DR Antigens', 'Humans', 'Interferon-gamma', 'Male', 'Middle Aged', 'Monocytes', 'Retinitis Pigmentosa', 'T-Lymphocytes'] | 3,123,268 | [['M01.060.116'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.360.340.024.340.415', 'G05.420.325'], ['D12.776.395.550.509.400', 'D12.776.543.550.440.400', 'D23.050.301.500.400.400', 'D23.050.301.500.450.400', 'D23.050.705.552.410.400', 'D23.050.705.552.450.400'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Innovative encapsulated oxygen-releasing beads for bioremediation of BTEX at high concentration in groundwater. | Both a low concentration of dissolved oxygen and the toxicity of a high concentration of BTEX inhibit the bioremediation of BTEX in groundwater. A novel method of preparing encapsulated oxygen-releasing beads (encap-ORBs) for the biodegradation of BTEX in groundwater was developed. Experimental results show that the in... | ['Benzene Derivatives', 'Biodegradation, Environmental', 'Groundwater', 'Oxygen', 'Polyvinyl Alcohol', 'Toluene', 'Water Pollutants, Chemical', 'Xylenes'] | 28,846,890 | [['D02.455.426.559.389'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G01.311.355'], ['D01.268.185.550', 'D01.362.670'], ['D02.033.750', 'D02.455.326.271.884.533.532', 'D05.750.716.721.616', 'D25.720.716.721.616', 'J01.637.051.720.716.721.616'], ['D02.455.426.559.389.832'], ['D27.888.284.903.655'], ['D02.455.426.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Infectious complications after multivisceral transplantation in adults. | UNLABELLED: It is thought that multivisceral transplantation requires high levels of immunosuppression and therefore, patients run an increased risk of infection. We retrospectively reviewed our center's experience with clinically relevant infectious complications.PATIENTS: Between 2000 and 2005, 10 adult patients unde... | ['Adult', 'Aged', 'Bacterial Infections', 'Female', 'Follow-Up Studies', 'Humans', 'Immunosuppression', 'Infections', 'Male', 'Middle Aged', 'Mycoses', 'Postoperative Complications', 'Retrospective Studies', 'Time Factors', 'Viscera'] | 17,098,039 | [['M01.060.116'], ['M01.060.116.100'], ['C01.150.252'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ['C01'], ['M01.060.116.630'], ['C01.150.703'], ['C23.550.767'], ['E05.318.372.500.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Suppression of an exocellular proteinase synthesis in Bacillus megaterium by increased temperature. | During cultivation of Bacillus megaterium at 42 degrees C the amount of the exocellular protease produced by growing cells sharply decreases as compared with temperatures of 28 and 35 degrees C. Within the above range the growth rate and incorporation of amino acids increase with increasing temperature. The culture ada... | ['Bacillus megaterium', 'Bacterial Proteins', 'Endopeptidases', 'Hot Temperature'] | 6,406,305 | [['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['D12.776.097'], ['D08.811.277.656.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.71... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Glucose enhancement of 24-h memory retrieval in healthy elderly humans. | When administered soon before or after training, glucose facilitates memory in rodents and in several populations of humans, including healthy elderly people. Thus, glucose appears to enhance memory formation in a time- and dose-dependent manner. By assessing the effects of glucose at the time of memory tests, the pres... | ['Aged', 'Aged, 80 and over', 'Blood Glucose', 'Dose-Response Relationship, Drug', 'Female', 'Glucose', 'Humans', 'Male', 'Memory', 'Mental Recall', 'Middle Aged'] | 9,659,988 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D09.947.875.359.448.500'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['M01.060.116.630']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
n of 1 trial for an ornithine transcarbamylase deficiency carrier. | Ornithine transcarbamylase deficiency (OTCD) is an X-linked disorder of the urea cycle. It is often fatal in affected males. Treatment for affected individuals includes dietary protein restriction, activation of alternative pathways of nitrogen excretion and L-arginine supplementation. Depending on the amount of X chro... | ['Affect', 'Arginine', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Genetic Diseases, X-Linked', 'Glutamine', 'Heterozygote', 'Humans', 'Male', 'Middle Aged', 'Ornithine Carbamoyltransferase', 'Ornithine Carbamoyltransferase Deficiency Disease', 'Quality of Life', 'Surveys and Questionnaires', 'X Chromosome ... | 18,343,177 | [['F01.470.047'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C16.320.322'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ['G05.380.383'... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Individual differences in the cortisol and salivary á-amylase awakening responses in early childhood: relations to age, sex, and sleep. | Recent studies have examined post-waking changes in cortisol as a marker of HPA functioning, but questions remain about the stability of this response, as well as its relation to sleep and other ANS markers. The purposes of this study were to a) examine the presence and developmental changes in the cortisol awakening r... | ['Age Factors', 'Cross-Sectional Studies', 'Female', 'Humans', 'Hydrocortisone', 'Individuality', 'Infant', 'Male', 'Saliva', 'Salivary alpha-Amylases', 'Sex Factors', 'Sleep', 'Wakefulness'] | 24,604,597 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['F01.752.488'], ['M01.060.703'], ['A12.200.666'], ['D08.811.277... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sequence analysis of ADARB1 gene in patients with familial bipolar disorder. | BACKGROUND: The ADARB1 gene is located in 21q22.3 region, previously linked to familial bipolar disorder, and its product has a documented action in the editing of the pre-mRNA of glutamate receptor B subunit. Dysfunction of glutamatergic neurotransmission could play an important role in the pathophysiology of bipolar ... | ['Adenosine Deaminase', 'Adolescent', 'Adult', 'Anticonvulsants', 'Bipolar Disorder', 'Chromosomes, Human, Pair 21', 'DNA Mutational Analysis', 'Female', 'Genetic Predisposition to Disease', 'Glutamic Acid', 'Humans', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Polymorphism, Genetic', 'RNA Precursors', 'RNA-Bind... | 15,183,604 | [['D08.811.277.151.486.075'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.080'], ['F03.084.500'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['E05.393.760.700.300'], ['C23.550.291.687.500', 'G05.380.355'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Associations between ethnicity, body composition, and bone mineral density in a Southeast Asian population. | CONTEXT AND OBJECTIVE: Chinese men in Singapore have a higher incidence of hip fractures than Malay and Indian men. We investigated whether there were corresponding ethnic differences in peak bone mineral density (BMD) in young men and whether differences in body composition influenced peak BMD.DESIGN AND SETTING: This... | ['Abdominal Fat', 'Adult', 'Asia, Southeastern', 'Asian Continental Ancestry Group', 'Body Composition', 'Body Mass Index', 'Bone Density', 'Cross-Sectional Studies', 'European Continental Ancestry Group', 'Femur Neck', 'Hip Fractures', 'Humans', 'Incidence', 'India', 'Lumbar Vertebrae', 'Malaysia', 'Male', 'Risk Facto... | 24,037,892 | [['A10.165.114.830.500'], ['M01.060.116'], ['Z01.252.145'], ['M01.686.508.200'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.... | ['Anatomy [A]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Renal failure in acute pancreatitis. Timing of dialysis and surgery. | UNLABELLED: Despite the progress in intensive care treatment the ongoing systemic inflammatory response syndrome (SIRS) in patients with severe pancreatitis (SP) and renal failure (RF) is associated with high mortality. The aim of this lecture is to outline the knowledge drawn from literature and personal experience an... | ['Acute Disease', 'Acute Kidney Injury', 'Decompression, Surgical', 'Humans', 'Pancreatitis', 'Renal Dialysis', 'Risk Factors'] | 11,202,287 | [['C23.550.291.125'], ['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.689.750'], ['E02.870.300', 'E02.912.800'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Applications of analytical ultracentrifugation to protein size-and-shape distribution and structure-and-function analyses. | The rebirth of modern analytical ultracentrifugation (AUC) began in 1990s. Since then many advanced AUC detectors have been developed that provide a vast range of versatile choices when characterizing the physical and chemical features of macromolecules. In addition, there have been remarkable advances in software that... | ['Apolipoprotein E3', 'Coronavirus 3C Proteases', 'Cysteine Endopeptidases', 'Humans', 'Kinetics', 'Lipids', 'Protein Structure, Quaternary', 'Structure-Activity Relationship', 'Ultracentrifugation'] | 21,087,667 | [['D10.532.091.500.500', 'D12.776.070.400.500.500', 'D12.776.521.120.500.500'], ['D08.811.277.656.262.500.108.500', 'D08.811.277.656.979.250.500', 'D12.776.964.900.500.500.500'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity. | Genomic copy number imbalances are being increasingly identified as an important cause of intellectual disability and behavioral abnormalities. The typical deletion in WAGR syndrome encompasses the PAX6 and WT1 genes, but larger deletions have been associated with neurobehavioral abnormalities and obesity. We identifie... | ['Attention Deficit Disorder with Hyperactivity', 'Autistic Disorder', 'Child', 'Chromosome Deletion', 'Chromosome Disorders', 'Chromosomes, Human, Pair 11', 'Developmental Disabilities', 'Humans', 'In Situ Hybridization, Fluorescence', 'Infant', 'Male', 'Microarray Analysis', 'Obesity', 'Oligonucleotide Array Sequence... | 21,567,907 | [['F03.625.094.150'], ['F03.625.164.113.500'], ['M01.060.406'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['C16.131.260', 'C16.320.180'], ['A11.284.187.520.300.325.355', 'G05.360.162.520.300.325.355'], ['F03.62... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
General practitioners' attitudes and decision making regarding admission for older adults with infection: a UK qualitative interview study. | BACKGROUND: The world has an ageing population. Infection is common in older adults; serious infection has a high mortality rate and is associated with unplanned admissions. In the UK, general practitioners (GPs) must identify which older patients require admission to hospital and provide appropriate care and support f... | ['Aged', 'Attitude of Health Personnel', 'Decision Making, Shared', 'Female', 'General Practitioners', 'Hospitalization', 'Humans', 'Infections', 'Interviews as Topic', 'Male', "Practice Patterns, Physicians'", 'Primary Health Care', 'Qualitative Research', 'Social Support', 'United Kingdom'] | 30,219,922 | [['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F02.463.785.810.250', 'I03.743.500'], ['M01.526.485.810.485', 'N02.360.810.485'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Geographicals [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Measures of cutaneous human papillomavirus infection in normal tissues as biomarkers of HPV in corresponding nonmelanoma skin cancers. | Cutaneous human papillomavirus (HPV) may be associated with the development of nonmelanoma skin cancer (NMSC), as suggested by reports of HPV DNA in NMSC tumors. HPV has also been investigated as an NMSC risk factor in epidemiologic studies, although findings vary across studies that used different biomarkers of HPV in... | ['Betapapillomavirus', 'Biomarkers', 'Carcinoma, Basal Cell', 'Carcinoma, Squamous Cell', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Papillomavirus Infections', 'Risk Factors', 'Skin Diseases, Viral', 'Skin Neoplasms'] | 18,729,188 | [['B04.280.210.655.100', 'B04.613.204.655.100'], ['D23.101'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Total obliteration of the mastoid, middle ear, and external auditory canal. A review of 27 cases. | In the past 22 years, 27 patients had undergone total obliteration of the mastoid, middle ear, and external auditory canal. Most of the patients had severely diseased ears, many with multiple previous operations. When performed for chronic otorrhea, the operation resulted in a dry ear in all but two cases, though heali... | ['Adolescent', 'Adult', 'Child', 'Chronic Disease', 'Ear Canal', 'Ear Diseases', 'Ear, Middle', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mastoid', 'Methods', 'Middle Aged', 'Postoperative Complications'] | 7,242,201 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C23.550.291.500'], ['A09.246.272.396'], ['C09.218'], ['A09.246.397'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.885.444'], ['E05.581'], ['M01.060.116.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Influence of celecoxib on invasiveness of human high-metastatic nasopharyngeal carcinoma cell line CNE-2Z]. | OBJECTIVE: To investigate the effect and mechanism (a selective cyclooxygenase-2 inhibitor) on invasive ability of human nasopharyngeal carcinoma (NPC) line CNE-2Z.METHODS: The proliferation of NPC cells was examined by MTT assay. The invasive and migrating ability of NPC cells was detected with transwell chamber. E-ca... | ['Apoptosis', 'Cadherins', 'Carcinoma, Squamous Cell', 'Celecoxib', 'Cell Line, Tumor', 'Cell Proliferation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Nasopharyngeal Neoplasms', 'Neoplasm Metastasis', 'Pyrazoles', 'Sulfonamides'] | 21,215,211 | [['G04.146.954.035'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.370'], ['B01.0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection. | Conceptually, blocking human immunodeficiency virus type 1 (HIV-1) integration is the last possibility for preventing irreversible cellular infection. Using cocultures of monocyte-derived dendritic cells and CD4(+) T cells, which represent primary targets in sexual transmission, we demonstrated that blocking integratio... | ['Anilides', 'Anti-HIV Agents', 'CD4-Positive T-Lymphocytes', 'Cell Line', 'Cells, Cultured', 'Coculture Techniques', 'Dendritic Cells', 'Female', 'Furans', 'HIV Infections', 'HIV Integrase Inhibitors', 'HIV-1', 'Humans', 'Male', 'Naphthyridines', 'Pyrimidines', 'Reverse Transcriptase Inhibitors', 'Thioamides', 'Virus ... | 18,474,579 | [['D02.065.199', 'D02.092.146.113'], ['D27.505.954.122.388.077.088'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.251.210'], ['A11.251'], ['E05.481.500.374'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D03.383.312'], ['C01.221.250... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of Leukocyte Telomere Length with Mild Cognitive Impairment and Alzheimer's Disease: Role of Folate and Homocysteine. | BACKGROUND: Leukocyte telomere length (LTL) is associated with the aging process and age-related degenerative diseases. The relation of peripheral blood LTL to mild cognitive impairment (MCI) and Alzheimer's disease (AD) and the role of folate and homocysteine (Hcy) in this relation remain unclear.OBJECTIVES: We aimed ... | ['Aged', 'Alzheimer Disease', 'Case-Control Studies', 'Cognitive Dysfunction', 'Correlation of Data', 'Female', 'Folic Acid', 'Homocysteine', 'Humans', 'Leukocytes', 'Male', 'Middle Aged', 'Telomere Shortening'] | 31,437,841 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F03.615.250.700'], ['H01.548.832.500'], ['D03.633.100.733.631.400'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Gastrointestinal transit in thyroid disease. | Diarrhea and malabsorption are common manifestations of hyperthyroidism, whereas constipation or obstipation frequently occur in hypothyroidism. Abnormalities of gastrointestinal motility have been proposed as the primary cause of these complaints, but documentation has been conflicting and largely limited to observati... | ['Adult', 'Aged', 'Constipation', 'Female', 'Gastric Acid', 'Gastric Emptying', 'Gastrointestinal Motility', 'Humans', 'Malabsorption Syndromes', 'Male', 'Metabolic Clearance Rate', 'Middle Aged', 'Thyroid Diseases', 'Time Factors'] | 6,706,068 | [['M01.060.116'], ['M01.060.116.100'], ['C23.888.821.150'], ['A12.200.307.603'], ['G10.261.360.400'], ['G10.261.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.637', 'C18.452.603'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['M01.060.116.630'], ['C19.874'], [... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Middle cerebral artery median peak systolic velocity validation: effect of measurement technique. | We sought to validate center-specific published medians and estimate the effects of sonologist and Doppler measurement techniques on middle cerebral artery (MCA) peak systolic velocity (PSV) values. We studied 154 gravidas with normal singletons who underwent MCA PSV measurement at 18 to 35 weeks' gestation by one of t... | ['Blood Flow Velocity', 'Female', 'Fetal Diseases', 'Fetus', 'Humans', 'Middle Cerebral Artery', 'Observer Variation', 'Pregnancy', 'Reference Standards', 'Rheology', 'Ultrasonography, Doppler, Color', 'Ultrasonography, Prenatal'] | 20,225,170 | [['E01.370.370.130', 'G09.330.380.630.080'], ['C13.703.277', 'C16.300'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.228.550'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['G08.686.784.769'], ['E05.978.808'], ['E05.830', 'H01.671.808'], ['E01.370.35... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Synergistic effects of ethanol and UV radiation to reduce levels of selected foodborne pathogenic bacteria. | The purpose of this study was to determine whether combined treatments would produce synergistic disinfection effects on food products during food processing compared with single treatments. We investigated the bactericidal effects of a commercial chemical disinfectant (ethanol) and of UV radiation on Bacillus cereus F... | ['Bacteria', 'Colony Count, Microbial', 'Consumer Product Safety', 'Disinfection', 'Dose-Response Relationship, Drug', 'Dose-Response Relationship, Radiation', 'Ethanol', 'Food Contamination', 'Food Irradiation', 'Food Microbiology', 'Humans', 'Ultraviolet Rays'] | 20,202,345 | [['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.850.210'], ['N06.850.780.200.450.850.375'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D02.033.375'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis. | OBJECTIVE: Previously, we described risk factors for disease progression in moderate asymptomatic carotid artery stenosis (ASCAS). The aim of the current study was to develop a risk prediction model for disease progression in this group.METHODS: All patients presenting between January 2005 and May 2012 with moderate (5... | ['Aged', 'Aged, 80 and over', 'Area Under Curve', 'Asymptomatic Diseases', 'Blood Flow Velocity', 'Carotid Artery, Common', 'Carotid Artery, Internal', 'Carotid Stenosis', 'Chi-Square Distribution', 'Decision Support Techniques', 'Disease Progression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis',... | 25,238,724 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['C23.550.291.187'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A07.015.114.186.200'], ['A07.015.114.186.200.230'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The effect of hydroxyurea on rabbit subconjunctival fibroblast culture and use of hydroxyurea in rabbits after glaucoma filtration surgery. | In an in vitro study, rabbit subconjunctival fibroblasts were cultured and the effects of an antineoplastic drug, hydroxyurea (HU), on fibroblast proliferation and fibroblast attachment was investigated. The effects of HU were compared with those of mitomycin C (MMC). Different concentrations of HU and MMC were added t... | ['Animals', 'Cell Adhesion', 'Cells, Cultured', 'Conjunctiva', 'Dose-Response Relationship, Drug', 'Fibroblasts', 'Filtering Surgery', 'Glaucoma', 'Hydroxyurea', 'Mitomycin', 'Nucleic Acid Synthesis Inhibitors', 'Postoperative Care', 'Rabbits'] | 10,516,520 | [['B01.050'], ['G04.022'], ['A11.251'], ['A09.371.060.200', 'A09.371.337.168'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.329.228'], ['E04.540.450'], ['C11.525.381'], ['D02.065.950.395'], ['D02.806.400.249.350', 'D03.383.097.500.350', 'D03.633.100.473.412.249.350'], ['D27.505.519.389.675'], ['E02.760.731.700', 'E04... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Towards functional glycomics by localization of binding sites for tissue lectins: lectin histochemical reactivity for galectins during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster. | Endogenous lectins act as effectors of cellular activities such as growth regulation, migration, and adhesion. Following their immunohistochemical localization in our previous study (Saussez et al. in Histochem Cell Biol 123:29-41, 2005) we purified several galectins and used them as tools for monitoring accessible bin... | ['Animals', 'Binding Sites', 'Biotin', 'Carcinogens', 'Cell Line', 'Cell Line, Tumor', 'Cricetinae', 'Diethylstilbestrol', 'Fluorescent Antibody Technique', 'Galectin 1', 'Galectin 3', 'Galectins', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'Kidney Neoplasms', 'Lectins', 'Male', 'Mesocricetus', 'Mic... | 16,435,123 | [['B01.050'], ['G02.111.570.120'], ['D03.383.129.308.080', 'D08.211.096'], ['D27.888.569.100'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.455.426.559.389.150.700.725.500'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Combined use of metformin and Diane35 in polycystic ovary syndrome]. | UNLABELLED: The aim of our study was to compare the effect of Metformin applied independently to the effect of Metformin used in combination with Diane35, the latter given only during the first two months of the treatment.METHODS: In this prospective, open clinical study, 30 women with PCOS were included, divided in tw... | ['Administration, Oral', 'Adolescent', 'Adult', 'Androgen Antagonists', 'Cyproterone Acetate', 'Drug Administration Schedule', 'Drug Combinations', 'Drug Therapy, Combination', 'Ethinyl Estradiol', 'Female', 'Humans', 'Metformin', 'Polycystic Ovary Syndrome', 'Prospective Studies', 'Treatment Outcome'] | 15,341,255 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['D06.347.065', 'D27.505.696.399.450.065'], ['D04.210.500.745.432.219.150', 'D04.210.500.883.419.150'], ['E02.319.283'], ['D26.310'], ['E02.319.310'], ['D04.210.500.668.651.568.291', 'D06.472.334.851.437.968.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Massive lymphocyte apoptosis in the thymus of functionally deficient TrkB mice. | The occurrence of TrkB in the murine thymus (15-day and 3-month old) was investigated by Northern blot, Western blot and immunohistochemistry. Furthermore, the thymus of 15-day-old mice carrying a non-functional mutation on trkB was analyzed. Both trkB mRNA and 145 kDa TrkB protein were detected. In addition, isolated ... | ['Animals', 'Apoptosis', 'Immunohistochemistry', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Microscopy, Electron', 'Mutation', 'Nerve Growth Factors', 'RNA, Messenger', 'Receptor, trkB', 'Stromal Cells', 'T-Lymphocytes', 'Thymus Gland'] | 12,161,017 | [['B01.050'], ['G04.146.954.035'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['B01.050.150.900.649.313.992.635.505.500'], ['B0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain Activation in Response to Personalized Behavioral and Physiological Feedback From Self-Monitoring Technology: Pilot Study. | BACKGROUND: The recent surge in commercially available wearable technology has allowed real-time self-monitoring of behavior (eg, physical activity) and physiology (eg, glucose levels). However, there is limited neuroimaging work (ie, functional magnetic resonance imaging [fMRI]) to identify how people's brains respond... | ['Adult', 'Brain', 'Exercise', 'Feedback, Physiological', 'Female', 'Health Behavior', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pilot Projects'] | 29,117,928 | [['M01.060.116'], ['A08.186.211'], ['G11.427.410.698.277', 'I03.350'], ['G07.410.732'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Estimating foodborne gastroenteritis, Australia. | We estimated for Australia the number of cases, hospitalizations, and deaths due to foodborne gastroenteritis in a typical year, circa 2000. The total amount of infectious gastroenteritis was measured by using a national telephone survey. The foodborne proportion was estimated from Australian data on each of 16 pathoge... | ['Australia', 'Computer Simulation', 'DNA Virus Infections', 'Foodborne Diseases', 'Gastroenteritis', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacterial Infections', 'Hospitalization', 'Humans', 'Incidence', 'Protozoan Infections', 'Public Health', 'RNA Virus Infections'] | 16,102,316 | [['Z01.639.100', 'Z01.678.100.373'], ['L01.224.160'], ['C01.925.256'], ['C25.723.415'], ['C06.405.205'], ['C01.150.252.400'], ['C01.150.252.410'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.8... | ['Geographicals [Z]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
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