Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotine patch for the prevention of postoperative nausea and vomiting: a prospective randomised trial. | BACKGROUND AND OBJECTIVE: It has been demonstrated that smoking significantly reduces postoperative nausea and vomiting (PONV). However, there are approximately 4000 substances in cigarette smoke that can be responsible for this effect. To demonstrate whether nicotine is the substance with antiemetic effects we applied... | ['Administration, Cutaneous', 'Antiemetics', 'Cholecystectomy, Laparoscopic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nicotine', 'Postoperative Nausea and Vomiting', 'Prospective Studies', 'Smoking'] | 17,638,396 | [['E02.319.267.120.060'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.760.570', 'D03.383.725.518'], ['C23.550.767.859', 'C23.888.821.712.700', 'C23.888.821.937.0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Speckle reduction in ultrasound medical images using adaptive filter based on second order statistics. | This article discusses an adaptive filtering technique for reducing speckle using second order statistics of the speckle pattern in ultrasound medical images. Several region-based adaptive filter techniques have been developed for speckle noise suppression, but there are no specific criteria for selecting the region gr... | ['Algorithms', 'Animals', 'Image Processing, Computer-Assisted', 'Liver', 'Signal Processing, Computer-Assisted', 'Spleen', 'Ultrasonography'] | 17,566,930 | [['G17.035', 'L01.224.050'], ['B01.050'], ['L01.224.308'], ['A03.620'], ['L01.224.800'], ['A10.549.700', 'A15.382.520.604.700'], ['E01.370.350.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Virus-induced asthma attack: The importance of allergic inflammation in response to viral antigen in an animal model of asthma. | Asthma exacerbation can be a life-threatening condition, and is most often triggered by common respiratory viruses. Poor asthma control and worsening of respiratory function is associated with increased airway inflammation, including eosinophilia. Prevention of asthma exacerbation relies on treatment with corticosteroi... | ['Animals', 'Anti-Inflammatory Agents', 'Asthma', 'Dexamethasone', 'Disease Models, Animal', 'Female', 'Guinea Pigs', 'Humans', 'Immunologic Memory', 'Inflammation', 'Lymphocytes', 'Parainfluenza Virus 1, Human', 'Respiratory Hypersensitivity', 'Respirovirus Infections'] | 28,742,120 | [['B01.050'], ['D27.505.954.158'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.500'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Should we modify our indications after the EVAR-2 trial conclusions? | BACKGROUND: To compare the results of the endovascular aneurysm repair (EVAR) in patients considered as unfit for surgery in a "high volume" center with the EVAR-2 trial results.METHODS: In our center, between January 2006 and December 2008, 469 endovascular aorta treatments were performed in high-risk patients. All th... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm, Abdominal', 'Aortography', 'Blood Vessel Prosthesis Implantation', 'Chi-Square Distribution', 'Endovascular Procedures', 'Evidence-Based Medicine', 'France', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Kaplan-Meier Estimate', 'Patient Selection', 'Platele... | 21,724,099 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['E04.100.814.868.500', 'E04.650.200'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.100.814.529', 'E04.502.382'], ['H... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Competing species in a changing climate: effects of recruitment disturbances on two interacting barnacle species. | 1. The climate is changing and data-based simulation models can be a valuable tool for predicting population response to such changes and investigate the mechanisms of population change. In this study, a data-based two-species matrix model was constructed to explore the possible effects of elevated sea surface temperat... | ['Animals', 'Atlantic Ocean', 'Climate', 'Ecology', 'Models, Biological', 'Population Density', 'Population Dynamics', 'Reproduction', 'Species Specificity', 'Thoracica', 'Time Factors'] | 16,689,959 | [['B01.050'], ['Z01.756.092'], ['G16.500.275.071', 'N06.230.300.100.250'], ['H01.158.273.248', 'H01.277.249'], ['E05.599.395'], ['N01.224.600', 'N06.850.505.400.600'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G08.686.784'], ['G16.824'], ['B01.050.500.131.365.880'], ['G01.910.857']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The cortisol response in policemen: intraindividual variation, not concentration level, predicts truncal obesity. | OBJECTIVES: Chronic stress, characteristic of police work, affects the hypothalamic-pituitary-adrenal axis' control of cortisol production. Capacity to vary cortisol may be the appropriate measurement to interpret associations with chronic diseases, including obesity, best measured by variability within a person, not c... | ['Adult', 'African Americans', 'Body Fat Distribution', 'Body Mass Index', 'Body Weights and Measures', 'Cross-Sectional Studies', 'European Continental Ancestry Group', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Obesity', 'Police', 'Saliva', 'Stress, Psychological'] | 23,606,277 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E01.370.600.115.100.062', 'G02.111.130.134', 'G03.180.134', 'G07.100.049.134'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['E05.318.372.500.875', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of the refolding of hen lysozyme from dimethyl sulfoxide and guanidinium chloride. | The folding of hen egg white lysozyme is complex, involving parallel pathways and distinct folding domains [Radford, S.E., Dobson, C.M., & Evans, P.A. (1992) Nature 358, 302-307]. In the present work the refolding of this protein from two denatured states that have different conformational properties, one generated by ... | ['Animals', 'Chickens', 'Circular Dichroism', 'Dimethyl Sulfoxide', 'Egg White', 'Female', 'Guanidine', 'Guanidines', 'Magnetic Resonance Spectroscopy', 'Muramidase', 'Protein Denaturation', 'Protein Folding', 'Protein Structure, Secondary'] | 7,849,031 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.867.151'], ['D02.886.640.150'], ['G07.203.300.470.700', 'J02.500.470.700'], ['D02.078.370.472'], ['D02.078.370'], ['E05.196.867.519'], ['D08.811.277.450.642'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G01.154.651', 'G02.111... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Reparative Effects of Poloxamer P188 in Astrocytes Exposed to Controlled Microcavitation. | Blast-induced traumatic brain injury (bTBI) is a neurological dysfunction that can result from a sudden exposure to shockwave and lead to adverse health consequences. Currently, there are no preventive measures that specifically target bTBI. Several hypotheses have been formulated to explain such injuries, including th... | ['Animals', 'Astrocytes', 'Blast Injuries', 'Brain Injuries, Traumatic', 'Calcium Signaling', 'Mice', 'Models, Biological', 'Poloxamer', 'Reactive Oxygen Species'] | 29,110,266 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['C26.120.126'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['D02.033.455.250.700.682', 'D05.750.741.667', 'D25.720.741.6... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Long-term results of talus fractures]. | In a retrospective study we analysed 29 operative treated fractures of the Talus. The classification of Marti and Weber has been used in this study. The incidence of necrosis was 17% of the group III and IV and that one of arthritis 27%. There was no infection in our series. We doubt that a longterm non weight-bearing ... | ['Adolescent', 'Adult', 'Aged', 'Bone Screws', 'Bone Wires', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Talus', 'Wound Healing'] | 1,497,967 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased episomal replication accounts for the high rate of adaptive mutation in recD mutants of Escherichia coli. | Adaptive mutation has been studied extensively in FC40, a strain of Escherichia coli that cannot metabolize lactose (Lac-) because of a frameshift mutation affecting the lacZ gene on its episome. recD mutants of FC40, in which the exonuclease activity of RecBCD (ExoV) is abolished but its helicase activity is retained,... | ['Adaptation, Physiological', 'Colony Count, Microbial', 'Electrophoresis, Gel, Pulsed-Field', 'Escherichia coli', 'Escherichia coli Proteins', 'Exodeoxyribonuclease V', 'Exodeoxyribonucleases', 'Genotype', 'Lactose', 'Models, Genetic', 'Mutation', 'Plasmids', 'Recombination, Genetic', 'Time Factors', 'beta-Galactosida... | 10,224,241 | [['G07.025', 'G16.012.500'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E05.196.401.220', 'E05.301.300.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D08.811.277.352.335.375.750'], ['D08.811.277.352.335.375', 'D08.811.277.352.365.290'], ['G05.380'], ['D09.698.629.305.340', 'D09... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Towards an environmentally-friendly laboratory: dimensionality and reactivity in the mechanosynthesis of metal-organic compounds. | We present a proof-of-principle study of an environmentally-friendly approach to laboratory research, in which the synthesis and structural characterisation of metal-organic complexes and frameworks are achieved without using bulk solvents; our study addresses the use of heteroditopic ligands for manipulating the dimen... | ['Green Chemistry Technology', 'Kinetics', 'Laboratories', 'Ligands', 'Organometallic Compounds', 'Research'] | 21,060,924 | [['J01.897.360'], ['G01.374.661', 'G02.111.490'], ['J03.520', 'N02.278.487'], ['D27.720.470.480'], ['D02.691'], ['H01.770.644']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Cranial growth after distraction osteogenesis of the craniosynostosis. | The authors describe the continuance of the growth of the distracted cranium after the reshaping of the cranium by distraction osteogenesis (DO) in children with simple symmetric and asymmetric craniosynostosis. From 2000 until 2002, 9 children with simple craniosynostosis underwent cranial reshaping by gradual distrac... | ['Cephalometry', 'Child, Preschool', 'Computer-Aided Design', 'Cranial Sutures', 'Craniosynostoses', 'External Fixators', 'Follow-Up Studies', 'Frontal Bone', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Infant', 'Longitudinal Studies', 'Occipital Bone', 'Osteogenesis, Distraction', '... | 18,216,664 | [['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406.448'], ['L01.224.108.150', 'L01.296.110.150'], ['A02.835.232.781.200'], ['C05.116.099.370.894.232', 'C05.660.207.240', 'C05.660.906.364', 'C16.131.621.207.240', 'C16.131.621.906.364'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Auditory event-related potentials demonstrate early cognitive impairment in children with subclinical hypothyroidism. | Background The aim of this study was to examine the cognitive functions of children with subclinical hypothyroidism (SH) and healthy children with the use of auditory event-related potentials (AERPs) and neuropsychological tests. Methods Twenty children aged between 8 and 17 years, diagnosed with SH, and 20 age-matched... | ['Adolescent', 'Case-Control Studies', 'Child', 'Cognitive Dysfunction', 'Evoked Potentials', 'Evoked Potentials, Auditory', 'Female', 'Follow-Up Studies', 'Humans', 'Hypothyroidism', 'Male', 'Neuropsychological Tests', 'Prognosis', 'Reaction Time'] | 31,194,683 | [['M01.060.057'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['F03.615.250.700'], ['G07.265.216.500', 'G11.561.200.500'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polymorphonuclear neutral protease activity in multiple sclerosis and other diseases. | Polymorphonuclear neutral protease activity (PMN-NPA) was examined in 87 patients with definite multiple sclerosis (MS) (48 active, 39 inactive), 49 patients with other neurological diseases (OND), 24 patients with immune-mediated non-neurological diseases (INND), and 32 normal subjects. PMN-NPA was found to be signifi... | ['Adult', 'Aged', 'Endopeptidases', 'Female', 'Humans', 'Kinetics', 'Male', 'Multiple Sclerosis', 'Neprilysin', 'Nervous System Diseases', 'Neutrophils'] | 3,907,490 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.656.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['D08.811.277.656.300.480.600', 'D08.811.277.656.675.374.600', 'D23.050.285.550', 'D23.101.140.500'], ['C10'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Plasma proatrial natriuretic peptide associates with lipid oxidation during exercise and cardiorespiratory fitness in healthy young adults. | Atrial natriuretic peptide (ANP) is known for its natriuretic, diuretic, and vasodilatory properties. However, ANP also has metabolic effects stimulating lipolysis and lipid oxidation. Overweight individuals have decreased circulating ANP concentrations. It has been proposed that this potential ANP deficiency could hav... | ['Atrial Natriuretic Factor', 'Body Mass Index', 'Cardiorespiratory Fitness', 'Exercise', 'Female', 'Humans', 'Lipid Peroxidation', 'Lipolysis', 'Male', 'Oxidation-Reduction', 'Oxygen Consumption', 'Respiratory Function Tests', 'Young Adult'] | 31,550,524 | [['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.685.500', 'I03.450.642.845.054.300', 'I03.450.642.845.054.800.500', 'N01.400.150', 'N01.400.545.500'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.98... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Addressing concerns about cisplatin application during pregnancy. | INTRODUCTION: Cervical cancer in second trimester of pregnancy is an oncologic challenge. Cisplatin is recommended to prevent cancer progression. This is a series correlating in vivo cisplatin concentration in the fetomaternal compartment and in breast milk with child development.METHODS: Eight consecutive patients wit... | ['Adult', 'Amniotic Fluid', 'Antineoplastic Agents', 'Cesarean Section', 'Cisplatin', 'Conization', 'Female', 'Fetal Blood', 'Gestational Age', 'Humans', 'Hysterectomy', 'Infant, Newborn', 'Lymph Node Excision', 'Milk, Human', 'Positron-Emission Tomography', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Pregnanc... | 21,391,877 | [['M01.060.116'], ['A12.098', 'A16.378.149'], ['D27.505.954.248'], ['E04.520.252.500'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E01.370.225.500.384.100.160', 'E01.370.225.998.054.160', 'E01.370.388.100.160', 'E04.074.160', 'E05.200.500.384.100.160', 'E05.200.998.054.160', 'E05.242.384.100.160'], ['A12.207.152.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Comparative study of self-expanding metal stent and intraluminal radioactive stent for inoperable esophageal squamous cell carcinoma. | BACKGROUND: We compared the effectiveness of self-expanding metal stent alone vs. radioactive stent embedded with 125I seeds implantation insertion in patients of inoperable esophageal squamous cell cancer combined with malignant esophageal stenosis.METHODS: We studied two groups of patients with stenosis attribute to ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brachytherapy', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Comparative Effectiveness Research', 'Esophageal Neoplasms', 'Esophageal Squamous Cell Carcinoma', 'Esophageal Stenosis', 'Female', 'Follow-Up Studies', 'Humans', 'Iodine Radioisotopes', 'Kaplan-Meier Estim... | 26,800,661 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.815.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['H01.770.644.145.360.500', 'N05.425.157'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['C04.557.470.200.400.330', 'C04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Defining Conditions for Optimal Inhibition of Food Intake in Rats by a Grape-Seed Derived Proanthocyanidin Extract. | Food intake depends on homeostatic and non-homeostatic factors. In order to use grape seed proanthocyanidins (GSPE) as food intake limiting agents, it is important to define the key characteristics of their bioactivity within this complex function. We treated rats with acute and chronic treatments of GSPE at different ... | ['Animals', 'Appetite Regulation', 'Dose-Response Relationship, Drug', 'Eating', 'Female', 'Glucagon-Like Peptide 1', 'Glucagon-Like Peptide-1 Receptor', 'Grape Seed Extract', 'Intestinal Mucosa', 'Proanthocyanidins', 'Rats', 'Rats, Wistar', 'Signal Transduction'] | 27,775,601 | [['B01.050'], ['G07.203.650.170', 'G07.203.650.390.070.290', 'G10.261.390.070.290'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.203.650.283', 'G10.261.330'], ['D06.472.317.680.500.500'], ['D12.776.543.750.695.021.500', 'D12.776.543.750.750.360.100.500'], ['D20.215.784.500.400', 'D26.667.500'], ['A03.556.124.369', 'A... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnostic accuracy of PCR for Jaagsiekte sheep retrovirus using field data from 125 Scottish sheep flocks. | Using a representative sample of Scottish sheep comprising 125 flocks, the sensitivity and specificity of PCR for Jaagsiekte sheep retrovirus (JSRV) was estimated. By combining and adapting existing methods, the characteristics of the diagnostic test were estimated (in the absence of a gold standard reference) using re... | ['Animals', 'Female', 'Jaagsiekte sheep retrovirus', 'Male', 'Polymerase Chain Reaction', 'Predictive Value of Tests', 'Pulmonary Adenomatosis, Ovine', 'Reproducibility of Results', 'Scotland', 'Sensitivity and Specificity', 'Sheep'] | 19,931,475 | [['B01.050'], ['B04.613.807.124.400', 'B04.820.650.124.400'], ['E05.393.620.500'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['C01.925.782.815.725', 'C01.925.928.740', 'C04.557.470.200.025.715', 'C22.836.715'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Osteochondral grafting for treatment of a massive chondral defect in the knee of a young adult with anterior cruciate ligament deficit. | We report the case of a 28-year-old woman who underwent osteochondral grafting and anterior cruciate ligament (ACL) reconstruction for treatment of a massive cartilage defect in a knee joint with ACL deficit. Arthroscopy showed a full-thickness degenerative cartilage defect measuring 22 x 35 mm in the weight-bearing ar... | ['Adult', 'Anterior Cruciate Ligament', 'Arthroscopy', 'Bone Transplantation', 'Cartilage, Articular', 'Female', 'Humans', 'Knee Injuries', 'Knee Joint'] | 17,868,845 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.835.5... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Decreased protein catabolism after exercise in subjects with IDDM. | We examined whether the increased rates of protein catabolism (proteolysis and leucine oxidation) associated with moderate insulinopenia in subjects with IDDM would be accentuated by prior bicycle exercise (53% VO2max for 82 min). Insulin infusions maintained plasma glucose concentrations on one study day in "tight" co... | ['Adolescent', 'Adult', 'Amino Acids, Branched-Chain', 'Blood Glucose', 'Blood Proteins', 'Diabetes Mellitus, Type 1', 'Fatty Acids, Nonesterified', 'Humans', 'Ketone Bodies', 'Male', 'Physical Exertion'] | 8,063,035 | [['M01.060.057'], ['M01.060.116'], ['D12.125.070'], ['D09.947.875.359.448.500'], ['D12.776.124'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D10.251.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522.585'], ['G11.427.683']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An insight into the environmental effects of the pocket of the active site of the enzyme. Ab initio ONIOM-molecular dynamics (MD) study on cytosine deaminase. | We applied the ONIOM-molecular dynamics (MD) method to cytosine deaminase to examine the environmental effects of the amino acid residues in the pocket of the active site on the substrate taking account of their thermal motion. The ab initio ONIOM-MD simulations show that the substrate uracil is strongly perturbed by t... | ['Binding Sites', 'Computer Simulation', 'Cytosine Deaminase', 'Hydrogen', 'Hydrogen Bonding', 'Methylation', 'Models, Molecular', 'Movement', 'Protein Structure, Tertiary', 'Software', 'Substrate Specificity', 'Temperature', 'Uracil'] | 17,663,441 | [['G02.111.570.120'], ['L01.224.160'], ['D08.811.277.151.486.625'], ['D01.268.406', 'D01.362.340'], ['G02.282'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['E05.599.595'], ['G07.568', 'G11.427.410'], ['G02.111.570.820.709.610'], ['L01.224.900'], ['G02.111.835'], ['G01.906.595', 'G16.500.275.063.725.710', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Vertically aligned GaAs nanowires on graphite and few-layer graphene: generic model and epitaxial growth. | By utilizing the reduced contact area of nanowires, we show that epitaxial growth of a broad range of semiconductors on graphene can in principle be achieved. A generic atomic model is presented which describes the epitaxial growth configurations applicable to all conventional semiconductor materials. The model is expe... | ['Arsenicals', 'Crystallization', 'Gallium', 'Graphite', 'Macromolecular Substances', 'Materials Testing', 'Molecular Conformation', 'Nanotubes', 'Particle Size', 'Surface Properties'] | 22,889,019 | [['D01.075', 'D02.129'], ['E05.196.300', 'G02.171'], ['D01.268.556.289', 'D01.552.544.289'], ['D01.268.150.300', 'D01.578.300'], ['D05'], ['E05.570'], ['G02.111.570.820'], ['J01.637.512.850'], ['G02.712'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Evaluation of the past history of chilblain in cases of systemic lupus erythematosus (SLE) and its similar diseases]. | We sent out a questionnaire to 47 patients of SLE and its similar diseases as to their past histories of chilblain. The results of the patients were compared to those of 141 cases of control. Although the percentage of cases who had revealed chilblain frequently (40.0%) and the age of chilblain onset (mean: 10.8 years ... | ['Adolescent', 'Adult', 'Aged', 'Chilblains', 'Female', 'Humans', 'Lupus Erythematosus, Cutaneous', 'Lupus Erythematosus, Systemic', 'Male', 'Medical History Taking', 'Middle Aged', 'Seasons', 'Sex Factors'] | 1,920,892 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C26.212.500.217', 'C26.417.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.475', 'C17.800.480'], ['C17.300.480', 'C20.111.590'], ['E01.370.510'], ['M01.060.116.630'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['N05.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changing pattern of hepatitis C virus spread in rural areas of Egypt. | BACKGROUND/AIMS: To identify patterns of HCV spread in the Nile Delta of Egypt.METHODS: Residents in a Nile Delta village were invited to participate in a cohort study of HCV infection. Risk factors for past or current infection were identified at cohort intake using generalized estimated equations models. Attributable... | ['Adolescent', 'Adult', 'Child', 'Egypt', 'Female', 'Hepatitis C', 'Humans', 'Male', 'Middle Aged', 'Models, Statistical', 'Prevalence', 'Risk Factors', 'Time Factors'] | 16,019,104 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['Z01.058.266.317'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Trends of spinal fusion surgery in Australia: 1997 to 2006. | BACKGROUND: This study aims to explore the trend in spine fusion surgery in Australia over the past 10 years, and to explore the possible influence of health insurance status (private versus public) on the rate of surgery.METHODS: Data pertaining to the rate of lumbar spine fusion from 1997 to 2006 were collected from ... | ['Australia', 'Humans', 'Insurance Coverage', 'Insurance, Health', 'National Health Programs', 'Private Sector', 'Spinal Fusion'] | 20,078,526 | [['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.265'], ['N03.219.521.576.343'], ['N03.349.550'], ['I01.791', 'N04.452.633.390'], ['E04.555.100.700']] | ['Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Thermodynamics of micelle formation in water, hydrophobic processes and surfactant self-assemblies. | The critical micelle concentration (c.m.c.) for four cationic surfactants, alkyl-trimethyl-ammonium bromides, was determined as a function of temperature by conductivity measurements. The values of the standard free energy of micellisation DeltaG degrees(mic) at different temperatures were calculated by using a pseudo-... | ['Cations', 'Gases', 'Hydrophobic and Hydrophilic Interactions', 'Micelles', 'Models, Molecular', 'Solubility', 'Surface-Active Agents', 'Temperature', 'Thermodynamics', 'Water'] | 18,688,390 | [['D01.248.497.300'], ['D01.362'], ['G02.409'], ['D05.374', 'D26.255.560'], ['E05.599.595'], ['G02.805'], ['D27.720.877'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Topography of remyelinated chronic spinal cord lesions in herpes simplex virus type 2 infections of mice. | Six-week-old outbred mice were infected intracerebrally with a low dose of the MS strain of herpes simplex virus type 2. About 1% of neurologically abnormal survivors developed paralysis or severe leg weakness during the first three weeks of infection. Weakness persisted with little subsequent improvement. Five to 8 mo... | ['Animals', 'Female', 'Herpes Simplex', 'Hindlimb', 'Mice', 'Multiple Sclerosis', 'Myelin Sheath', 'Nerve Fibers, Myelinated', 'Nerve Regeneration', 'Peripheral Nerves', 'Spinal Cord'] | 6,655,486 | [['B01.050'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['A13.473'], ['B01.050.150.900.649.313.992.635.505.500'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149.165.6... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Kinetics of formation of the primary compound (compound I) from hydrogen peroxide and turnip peroxidases. | A kinetic study of the reaction of two turnip peroxidases (P1 and P7) with hydrogen peroxide to form the primary oxidized compound (compound I) has been carried out over the pH range from 2.4 to 10.8. In the neutral and acidic pH regions, the rates depend linearly on hydrogen peroxide concentration whereas at alkaline ... | ['Glycerol', 'Hydrogen Peroxide', 'Hydrogen-Ion Concentration', 'Kinetics', 'Peroxidases', 'Plants'] | 28,821 | [['D02.033.800.875.500', 'D09.853.875.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.732'], ['B01.650']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of anti-MuLV cytotoxic T lymphocytes in the AKR.H-2b and AKR.H-2b:Fv-1b mouse strains. | Following secondary in vitro sensitization with AKR/Gross virus-induced tumors, AKR.H-2b:Fv-1b mice develop cytotoxic T lymphocytes (CTL) specific for AKR/Gross viral antigens. It has recently been determined that the responder status of AKR.H-2b:Fv-1b to AKR/Gross virus declines with age. The nonresponsiveness observe... | ['AKR murine leukemia virus', 'Age Factors', 'Animals', 'Antigens, Viral', 'Cytotoxicity, Immunologic', 'Friend murine leukemia virus', 'Genes, MHC Class II', 'Immune Tolerance', 'Immunity, Cellular', 'Immunologic Memory', 'Leukemia Virus, Murine', 'Mice', 'Mice, Inbred AKR', 'Moloney murine leukemia virus', 'Rauscher ... | 2,834,071 | [['B04.613.807.375.525.050', 'B04.820.650.375.525.050'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D23.050.327'], ['G12.287'], ['B04.613.807.375.525.225', 'B04.820.650.375.525.225'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['G12.535.425'], ['G12.450.050.400'], ['G... | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Risk and circumstances in which people are bitten by dogs in Cracow-- observations from the Consulting Clinic of Infectious Diseases]. | Inquiries about incidence of bites people by dogs have been made in the Consulting Ward for prophylactics of rabies of Chair and Department of Infectious Diseases in Cracow. There are frequent cases of people bitten by dogs, which usually occur in the streets. Victims are usually young. In the most cases there are not ... | ['Adolescent', 'Adult', 'Animals', 'Behavior', 'Bites and Stings', 'Child', 'Dogs', 'Humans', 'Incidence', 'Poland', 'Risk Factors', 'Social Responsibility'] | 8,754,322 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['F01.145'], ['C25.723.127', 'C26.176'], ['M01.060.406'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.... | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Long-term Outcomes of Laparoscopic Versus Open Surgery for Clinical Stage II/III Gastric Cancer: A Multicenter Cohort Study in Japan (LOC-A Study). | OBJECTIVE: A large-scale multicenter historical cohort study was conducted to investigate the efficacy of laparoscopic gastrectomy (LG) in comparison to open gastrectomy (OG) for locally advanced gastric cancer.BACKGROUND: LG is now practiced widely, but its applicability for advanced gastric cancer is still controvers... | ['Adenocarcinoma', 'Aged', 'Cohort Studies', 'Female', 'Gastrectomy', 'Humans', 'Japan', 'Laparoscopy', 'Male', 'Neoplasm Staging', 'Retrospective Studies', 'Stomach Neoplasms', 'Time Factors', 'Treatment Outcome'] | 29,697,447 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.789.625'], ['E05.318.372.500.500.500', 'E0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cerebral gumma. | A patient presented with symptoms from a tumour in the frontal region. Syphilis had been treated 15 years earlier but the serological tests were inconclusive on this admission. The CT-scan showed oedema surrounding a contrast enhancing tumour. Angiography showed displaced but otherwise normal vessels. Histologically th... | ['Adult', 'Brain Diseases', 'Humans', 'Male', 'Neurosyphilis', 'Radiography'] | 3,268,149 | [['M01.060.116'], ['C10.228.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.223.600', 'C01.150.252.400.794.840.500.750', 'C01.150.252.400.840.500.750', 'C01.207.180.600', 'C10.228.228.180.600'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Favorable Clinical Outcomes of Transcatheter Aortic Valve Implantation in Japanese Patients?- First Report From the Post-Approval K-TAVI Registry. | BACKGROUND: Very limited data exist on the outcomes of transcatheter aortic valve implantation (TAVI) since Japanese marketing approval of the first TAVI device.Methods and Results:The Kyoto University-related hospital Transcatheter Aortic Valve Implantation (K-TAVI) registry includes prospectively collected data from ... | ['Aged', 'Aged, 80 and over', 'Aortic Valve Stenosis', 'Asian Continental Ancestry Group', 'Disease-Free Survival', 'Female', 'Humans', 'Japan', 'Male', 'Prospective Studies', 'Registries', 'Survival Rate', 'Transcatheter Aortic Valve Replacement'] | 27,916,776 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.484.048.750', 'C14.280.955.249'], ['M01.686.508.200'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A study on the immunological basis of the dissociation between type I-hypersensitivity skin reactions to Blomia tropicalis antigens and serum anti-B. tropicalis IgE antibodies. | BACKGROUND: Two conditions are used as markers of atopy: the presence of circulating anti-allergen IgE antibodies and the presence of positive skin prick test (SPT) reactions to allergenic extracts. The correlation between these conditions is not absolute. This study aimed at investigating immunological parameters that... | ['Animals', 'Antigens', 'Ascaris lumbricoides', 'Blood Cells', 'Carbohydrates', 'Cross Reactions', 'Epitopes', 'Humans', 'Hypersensitivity, Immediate', 'Immunoglobulin E', 'Interleukin-10', 'Mites', 'Skin', 'Skin Tests'] | 21,631,925 | [['B01.050'], ['D23.050'], ['B01.050.500.500.294.400.500.100.108.425'], ['A11.118', 'A15.145.229'], ['D09'], ['G12.122.281'], ['D23.050.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maytenin Plays a Special Role in the Regulation of the Endophytic Bacillus megaterium in Peritassa campestris Adventitious Roots. | Peritassa campestris (Celastraceae) root bark accumulates potent antitumor quinonemethide triterpenes (QMTs). When grown in their natural habitat, plants of the family Celastraceae produce different QMTs such as celastrol (3) and pristimerin (4). However, when they are inserted in in vitro culture systems, they accumul... | ['Anti-Infective Agents', 'Antineoplastic Agents', 'Bacillus megaterium', 'Celastraceae', 'Endophytes', 'Plant Extracts', 'Plant Roots', 'Time Factors', 'Triterpenes'] | 31,422,514 | [['D27.505.954.122'], ['D27.505.954.248'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['B01.650.940.800.575.912.250.859.500.750'], ['B05.237'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['G01.910.857'], ['D02.45... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peptide-biphenyl hybrids as calpain inhibitors. | Calpain is a cysteine protease that is activated by Ca2+. The over-activation of calpain, which occurs on increasing Ca2+ concentration, causes a variety of diseases. This paper reports experimental results on the inhibition of calpain I (mu-calpain) by peptide-biphenyl hybrids. We have found that some peptide-biphenyl... | ['Biphenyl Compounds', 'Glycoproteins', 'Peptides'] | 17,191,858 | [['D02.455.426.559.389.185'], ['D09.400.430', 'D12.776.395'], ['D12.644']] | ['Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alpha-linolenic acid enhances the phagocytic and secretory functions of alternatively activated macrophages in part via changes to the oxylipin profile. | Alternatively activated macrophages are innate immune cells that contribute to resolution of inflammation and maintenance of homeostasis. Modulation of available fatty acid sources is thought to affect cellular physiology through a variety of mechanisms, including through alterations to the profile of oxygenated free f... | ['Arachidonate 15-Lipoxygenase', 'Chemokine CCL2', 'Cytokines', 'Humans', 'Lipopolysaccharides', 'Lipoxygenase Inhibitors', 'Macrophage Activation', 'Macrophages', 'Oxylipins', 'Phagocytosis', 'Phospholipases A2', 'THP-1 Cells', 'alpha-Linolenic Acid'] | 31,811,954 | [['D08.811.682.690.416.583.500.065', 'D12.776.556.579.374.568.500.030'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor. | Bone can adapt its structure in response to mechanical stimuli. At the cellular level, this involves changes in chromatin organization, gene expression, and differentiation, but the underlying mechanisms are poorly understood. Here we report on the involvement of RUNX2, a bone-related transcription factor, in this proc... | ['Acetylation', 'Animals', 'Biomechanical Phenomena', 'Bone and Bones', 'Cell Line', 'Cell Nucleus', 'Chromatin', 'Core Binding Factor Alpha 1 Subunit', 'Extracellular Signal-Regulated MAP Kinases', 'Gene Expression Regulation', 'Histones', 'Mice', 'Mice, Inbred C57BL', 'Models, Biological', 'Osteoblasts', 'Phosphoryla... | 22,337,141 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['A02.835.232', 'A10.165.265'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.930.155.200.100'], ['D08.811.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Faculty preparation: is clinical specialization a benefit or a deterrent to quality nursing education? | This article presents a point of view regarding the impact of specialty preparation at the master's level on performance as a faculty member in an entry-level program. Essentially, the focus in depth on a particular branch of nursing practice restricts the perception of the individual to the role and demands of the beg... | ['Clinical Competence', 'Curriculum', 'Education, Nursing, Baccalaureate', 'Education, Nursing, Graduate', 'Faculty, Nursing', 'Health Services Needs and Demand', 'Humans', "Nurse's Role", 'Nursing Education Research', 'Specialties, Nursing', 'Teaching'] | 14,870,906 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.462.316'], ['I02.358.337.450', 'I02.358.462.565'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
A spectroscopic and theoretical investigation of a free-base meso-trithienylcorrole. | The unique optical properties of free-base meso-tris(5-methylthien-2-yl)corrole were compared to those of the widely investigated meso-triphenyl-substituted analogue. A combination of spectroscopic and computational experiments was undertaken to elucidate the relationship between structural features of the neutral, mon... | ['Porphyrins', 'Proton Magnetic Resonance Spectroscopy', 'Spectrometry, Mass, Electrospray Ionization', 'Spectrophotometry, Ultraviolet'] | 24,303,811 | [['D03.383.129.578.840.500', 'D03.633.400.909.500', 'D04.345.783.500', 'D23.767.727'], ['E05.196.867.519.775'], ['E05.196.566.600'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma. | OBJECTIVE: To investigate the antitumor effects of intrasplenically transplanted interleukin-18 (IL-18) gene-modified hepatocytes on murine implanted liver carcinoma.METHODS: Embryonic murine hepatocyte cell line (BNL-CL2) was transfected with a recombinant adenovirus encoding IL-18 and used as delivery cells for IL-18... | ['Adenoviridae', 'Animals', 'Cell Line', 'Gene Transfer Techniques', 'Genetic Therapy', 'Genetic Vectors', 'Hepatocytes', 'Interleukin-18', 'Liver Neoplasms, Experimental', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Neoplasm Transplantation', 'T-Lymphocytes, Helper-Inducer', 'Transfection'] | 14,570,604 | [['B04.280.030'], ['B01.050'], ['A11.251.210'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['A11.436.348'], ['D12.644.276.374.465.518', 'D12.776.467.374.465.518', 'D23.529.374.465.518'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['B01... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis. | In order to determine key MMPs for invasion and metastasis in various human cancers, we examined the expression of ten MMPs (MMP-1, 2, 3, 7, 8, 9, 13 and MT1, 2, 3-MMPs) and tissue inhibitors of metalloproteinases (TIMP-1 and 2) in breast carcinomas, thyroid papillary carcinomas, endometrial carcinomas, ovarian carcino... | ['Extracellular Matrix', 'Female', 'Humans', 'Matrix Metalloproteinases', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Neoplasms', 'Tissue Inhibitor of Metalloproteinase-1', 'Tissue Inhibitor of Metalloproteinase-2', 'Tumor Cells, Cultured'] | 11,217,446 | [['A11.284.295.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.525', 'D08.811.277.656.675.374.525'], ['C04.697.645', 'C23.550.727.645'], ['C04.697.650', 'C23.550.727.650'], ['C04'], ['D12.776.645.875.450'], ['D12.776.645.875.500'], ['A11.251.860']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical and morphological features of gold neuropathy. | Three cases of gold-related neuropathy are reported. Clinical features include an acute, symmetrically progressive polyneuropathy, focal or generalized myokymia and a tendency for initial neurological deterioration followed by improvement, after cessation of chrysotherapy. The degree of clinical recovery related to max... | ['Adult', 'Aged', 'Animals', 'Arthritis, Rheumatoid', 'Chickens', 'Female', 'Gold', 'Humans', 'Male', 'Middle Aged', 'Peripheral Nerves', 'Peripheral Nervous System Diseases', 'Sural Nerve'] | 6,251,941 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incidence and mortality of sepsis, severe sepsis, and septic shock in intensive care unit patients with candidemia. | In this incidence study, of 16 074 patients admitted to the intensive care unit (ICU) from 1/1/2003 to 7/31/2011, 161 cases of candidemia were identified. The incidence of sepsis (27%), severe sepsis (31%), and septic shock (40%) was remarkably high in these cases of candidemia, as was the all-cause in-hospital mortali... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Candida', 'Candidemia', 'Female', 'Hospital Mortality', 'Humans', 'Incidence', 'Intensive Care Units', 'Length of Stay', 'Male', 'Middle Aged', 'Prospective Studies', 'Sepsis', 'Shock, Septic', 'Time Factors', 'United States', 'Young Adult'] | 25,811,137 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['C01.150.703.160.175.500', 'C01.150.703.492.500.500', 'C01.757.360.150', 'C23.550.470.790.500.360.150'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.97... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The Ded1 DEAD box helicase interacts with Chk1 and Cdc2. | Ded1 is a fission yeast DEAD box protein involved in translation. We isolated Ded1 in a screen for multi-copy suppressors of a cold-sensitive, loss-of-function mutant of the cyclin-dependent kinase Cdc2. The checkpoint protein kinase Chk1, required for cell cycle arrest in response to DNA damage, was also isolated in t... | ['CDC2 Protein Kinase', 'Cell Cycle', 'Cell Cycle Proteins', 'Checkpoint Kinase 1', 'DEAD-box RNA Helicases', 'DNA Damage', 'Fungal Proteins', 'Hot Temperature', 'Immunoblotting', 'MAP Kinase Signaling System', 'Models, Biological', 'Mutation', 'Phenotype', 'Protein Binding', 'Protein Biosynthesis', 'Protein Kinases', ... | 11,711,540 | [['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.776.744.360'], ['G04.144'], ['D12.776.167'], ['D08.811.91... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Phosphatase-negative Staphylococcus epidermidis]. | As a result of the study of a number of additional characteristics, more than a half of the cultures, formerly identified as phosphatase-negative S. epidermidis according to the scheme of the International Subcommittee on the Taxonomy of Staphylococci and Micrococci, have been shown to be more similar to S. Hominis and... | ['Coagulase', 'Genetic Variation', 'Phosphoric Monoester Hydrolases', 'Species Specificity', 'Staphylococcus'] | 6,270,934 | [['D08.811.277.656.300.174', 'D12.776.097.181'], ['G05.365'], ['D08.811.277.352.650'], ['G16.824'], ['B03.300.390.400.800.750', 'B03.353.500.750.750', 'B03.510.100.750.750', 'B03.510.400.790.750']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wilms' tumor in an adult with multiple osteoblastic metastases. | A rare case of Wilms' tumor in an adult with initial symptoms of unilateral exophthalmos and multiple osteoblastic metastases is reported. | ['Adult', 'Bone Neoplasms', 'Humans', 'Kidney Neoplasms', 'Male', 'Orbital Neoplasms', 'Wilms Tumor'] | 6,324,401 | [['M01.060.116'], ['C04.588.149', 'C05.116.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.588.149.721.656', 'C04.588.364.659', 'C05.116.231.754.659', 'C11.319.457', 'C11.675.659'], ['C04.557.435.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A formula for the displacement of an arch wire when subjected to a second-order couple. | A new formula, expressing the local angular displacement of an orthodontic beam when subjected to a second-order couple applied at midspan, has been developed and analyzed. The computed displacements were compared with the results of ex vivo testing. There was good agreement between the results from the theoretical eva... | ['Algorithms', 'Elasticity', 'Humans', 'Linear Models', 'Models, Biological', 'Models, Theoretical', 'Nonlinear Dynamics', 'Orthodontic Brackets', 'Orthodontic Wires', 'Pliability', 'Rotation', 'Stainless Steel', 'Stress, Mechanical', 'Surface Properties'] | 9,637,566 | [['G17.035', 'L01.224.050'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.599.395'], ['E05.599'], ['E05.599.850', 'H01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Section thickness and mitotic counts in ovarian mucinous carcinoma. Methodological study with scanning confocal microscopy. | To study the effect of section thickness on mitotic counts, paraffin sections of 28 cases of mucinous ovarian carcinomas were analyzed. Mitotic counts, estimated with the number of mitoses per mm2 of neoplastic epithelium (M/Vv index) and per mm3 from optical sections and through the whole section thickness were done. ... | ['Adenocarcinoma, Mucinous', 'Female', 'Histological Techniques', 'Humans', 'Microscopy, Confocal', 'Mitotic Index', 'Ovarian Neoplasms', 'Paraffin Embedding'] | 8,798,286 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['E01.370.225.750', 'E05.200.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'], ['E01.370.225.500.385.500', 'E05.200.500.385.500', 'E05.242.385.500'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', '... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibitory Effect of Spice Powders on the Development of Heated and Irradiated Bacillus subtilis Spores as Evaluated by Calorimetry. | Inhibitory effects of the powders of paprika, red pepper, black pepper, sage, oregano and thyme in a solid medium after heat treatment and gamma-irradiation on the development from spore of Bacillus subtilis were examined using calorimetry. Based on the f(t) curve (Antoce et al., 1996) from the thermogram obtained, two... | ['Bacillus subtilis', 'Calorimetry', 'Capsicum', 'Dose-Response Relationship, Drug', 'Gamma Rays', 'Hot Temperature', 'Microbial Viability', 'Origanum', 'Piper nigrum', 'Plant Preparations', 'Powders', 'Salvia officinalis', 'Spices', 'Spores, Bacterial', 'Thymus Plant'] | 30,249,961 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['E05.196.131'], ['B01.650.940.800.575.912.250.908.500.145'], ['G07.690.773.875', 'G07.690.936.500'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['G01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Study of triacylglycerol polymorphs by nuclear magnetic resonance: effects of temperature and chain length on relaxation parameters. | It is very important to monitor the characteristics of triacylglycerol crystal network in fats, as these crystals have an impact on many food properties such as texture, sensory taste, and extended shelf life. Although time-domain NMR (TD-NMR) is now the reference technique to determine the solid fat index in food, the... | ['Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Molecular Weight', 'Phase Transition', 'Sensitivity and Specificity', 'Spin Labels', 'Temperature', 'Triglycerides'] | 18,357,571 | [['E05.196.867.519'], ['G02.111.570.820'], ['G02.494'], ['G01.645', 'G02.734'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['D02.389.678'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pulmonary hemodynamics in the obstructive sleep apnea syndrome. Results in 220 consecutive patients. | We have investigated pulmonary hemodynamics in a large series of consecutive, unselected patients with obstructive sleep apnea syndrome (OSAS). The aims of this study were to evaluate the frequency of pulmonary artery hypertension (PH) in OSAS and to analyze, as far as possible, its mechanisms. Two hundred twenty patie... | ['Adult', 'Aged', 'Female', 'Hemodynamics', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Prospective Studies', 'Respiratory Function Tests', 'Respiratory Mechanics', 'Sleep Apnea Syndromes'] | 8,620,709 | [['M01.060.116'], ['M01.060.116.100'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.370.386.700'], ['G09.772.705.700'], ['C08.618.085.852', 'C10.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Spectroscopic determination of aboveground biomass in grasslands using spectral transformations, Support Vector Machine and Partial Least Squares Regression. | Aboveground biomass (AGB) is one of the strategic biophysical variables of interest in vegetation studies. The main objective of this study was to evaluate the Support Vector Machine (SVM) and Partial Least Squares Regression (PLSR) for estimating the AGB of grasslands from field spectrometer data and to find out which... | ['Algorithms', 'Biomass', 'Data Interpretation, Statistical', 'Environmental Monitoring', 'Least-Squares Analysis', 'Poaceae', 'Regression Analysis', 'Spectrum Analysis', 'Support Vector Machine'] | 23,925,082 | [['G17.035', 'L01.224.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['B01.650.940.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Targeting of the BclA and BclB proteins to the Bacillus anthracis spore surface. | The exosporium is the outermost layer of the Bacillus anthracis spore. The predominant protein on the exosporium surface is BclA, a collagen-like glycoprotein. BclA is incorporated on the spore surface late in the B. anthracis sporulation pathway. A second collagen-like protein, BclB, has been shown to be surface-expos... | ['Bacillus anthracis', 'Cytoplasm', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Membrane Glycoproteins', 'Protein Sorting Signals', 'Protein Structure, Tertiary', 'Protein Transport', 'Recombinant Fusion Proteins', 'Spores, Bacterial'] | 18,761,690 | [['B03.300.390.400.158.218.151', 'B03.353.500.100.218.151', 'B03.510.100.100.218.151', 'B03.510.415.400.158.218.151', 'B03.510.460.410.158.218.151'], ['A11.284.430.214'], ['G05.360.340.024.340.435'], ['D12.776.532.265'], ['D12.776.395.550', 'D12.776.543.550'], ['D12.644.770', 'G02.111.570.060.670'], ['G02.111.570.820.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neural responses to food stimuli among individuals with eating and weight disorders: a systematic review of event-related potentials. | A systematic review was conducted to investigate event-related potentials (ERPs) in response to food and non-food stimuli among individuals with eating and weight disorders. Limiting the search to studies that have analysed ERPs relating to motivated attention and inhibitory control, 19 research papers were extracted f... | ['Attentional Bias', 'Craving', 'Evoked Potentials', 'Feeding Behavior', 'Feeding and Eating Disorders', 'Food', 'Humans', 'Hunger', 'Inhibition, Psychological', 'Overweight'] | 31,246,114 | [['F02.830.104.214.500'], ['F01.658.293.195'], ['G07.265.216.500', 'G11.561.200.500'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F03.400'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.293.391', 'G07.203.650.390', 'G10.261.390'], ['F01.145.544', 'F02.463.425.475'... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Familial preductal aortic coarctation. Report on a sibling observation]. | The cases of two siblings, who died of preductal coarctation of the aorta, are reported. The rare familiar congenital cardiopathies are of special importance for the etiological questions and for judgement of the prognosis of inheritance. | ['Aortic Coarctation', 'Autopsy', 'Ductus Arteriosus', 'Humans', 'Infant, Newborn', 'Male'] | 1,258,512 | [['C14.240.400.090', 'C14.280.400.090', 'C16.131.240.400.090'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['A07.541.278.395', 'A16.378.303.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Inline fluid dynamics in piggyback and manifold drug delivery systems. | Inline mixing characteristics of primary and secondary i.v. solutions were evaluated for the piggyback and manifold systems. Dextrose (5%) and sodium chloride (0.9%) were used as markers for the primary and secondary solutions, respectively. With a 120-mL/hr flow rate, samples (up to 180) were collected over 36 minutes... | ['Drug Therapy, Combination', 'Glucose', 'Infusion Pumps', 'Intensive Care Units', 'Models, Theoretical', 'Pharmaceutical Preparations', 'Sodium Chloride', 'Solutions', 'Time Factors'] | 2,712,034 | [['E02.319.310'], ['D09.947.875.359.448'], ['E07.505', 'E07.858.082.505'], ['N02.278.388.493'], ['E05.599'], ['D26'], ['D01.210.450.150.875', 'D01.857.650'], ['D26.776'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Meta-analysis of multiple outcomes: a multilevel approach. | In meta-analysis, dependent effect sizes are very common. An example is where in one or more studies the effect of an intervention is evaluated on multiple outcome variables for the same sample of participants. In this paper, we evaluate a three-level meta-analytic model to account for this kind of dependence, extendin... | ['Computer Simulation', 'Data Interpretation, Statistical', 'Humans', 'Meta-Analysis as Topic', 'Reference Standards', 'Sample Size', 'Sampling Studies', 'Treatment Outcome'] | 25,361,866 | [['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500', 'E05.581.500.501', 'N05.715.360.325.515', 'N06.850.520.445.500'], ['E05.978.808'], ['E05.318.370.762', 'E05.581.500.902', 'N... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3'-azido-3'-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM). | The metabolism and cytostatic effects of 3'-azido-3'-deoxythymidine (AZT), one of the most effective agents being used in the treatment of acquired immunodeficiency syndrome, were investigated in the CCRF-CEM line of human T lymphoid cells. The concentration of drug required to inhibit cell growth by 50% (CD50) was sig... | ['Cell Division', 'Cell Line', 'Chromatography, High Pressure Liquid', 'DNA Replication', 'Deoxyribonucleotides', 'Dideoxynucleotides', 'Flow Cytometry', 'Kinetics', 'T-Lymphocytes', 'Thymine Nucleotides', 'Tumor Cells, Cultured', 'Zidovudine'] | 2,338,944 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['E05.196.181.400.300'], ['G02.111.225', 'G05.226'], ['D13.695.201'], ['D13.695.225'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
US childhood asthma prevalence estimates: the Impact of the 1997 National Health Interview Survey redesign. | The 1997 redesign of the National Health Interview Survey (NHIS) affected US childhood asthma prevalence estimates. The 1997 asthma attack prevalence estimate for children 0-17 years was 5.4%. Pre-redesign NHIS childhood asthma period prevalence estimates peaked in 1995 at 7.5%. It is unclear whether the difference ref... | ['Adolescent', 'Asthma', 'Child', 'Child, Preschool', 'Confidence Intervals', 'Health Surveys', 'Humans', 'Infant', 'Population Surveillance', 'Prevalence', 'United States'] | 12,851,220 | [['M01.060.057'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Epigenomic Reprogramming of Adult Cardiomyocyte-Derived Cardiac Progenitor Cells. | It has been believed that mammalian adult cardiomyocytes (ACMs) are terminally-differentiated and are unable to proliferate. Recently, using a bi-transgenic ACM fate mapping mouse model and an in vitro culture system, we demonstrated that adult mouse cardiomyocytes were able to dedifferentiate into cardiac progenitor-l... | ['Animals', 'Cell Dedifferentiation', 'Cellular Reprogramming', 'Cellular Reprogramming Techniques', 'Cluster Analysis', 'DNA Methylation', 'Epigenesis, Genetic', 'Epigenomics', 'Gene Expression Profiling', 'Induced Pluripotent Stem Cells', 'Mice', 'Models, Biological', 'Myoblasts, Cardiac', 'Myocardium', 'Myocytes, Ca... | 26,657,817 | [['B01.050'], ['G04.148'], ['G04.152.262', 'G05.135'], ['E05.200.500.380', 'E05.242.378', 'E05.393.085'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.308.203'], ['H01.158.273.180.350.074', 'H01.158.273.343.350.042'], ['E0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Web-based decision support for clinical trial eligibility determination in an international clinical trials network. | Matching individuals to multisite cooperative clinical trials can be a complex and nonintuitive decision process that expends considerable time and may be prone to errors. We developed and tested a web-based decision support tool to aid investigators in matching patients to open clinical trials for children with rhabdo... | ['Child', 'Controlled Clinical Trials as Topic', 'Decision Support Techniques', 'Feasibility Studies', 'Humans', 'Internet', 'Patient Selection', 'Program Development', 'Rhabdomyosarcoma'] | 14,662,275 | [['M01.060.406'], ['E05.318.372.250.250.365', 'N05.715.360.330.250.250.365', 'N06.850.520.450.250.250.365'], ['E05.245', 'L01.313.500.750.190'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E05.581.500.653',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Poor antenatal care in 20 French districts: risk factors and pregnancy outcome. | STUDY OBJECTIVE: Poor attendance to antenatal visits was studied to identify risk factors and to analyse the association with adverse pregnancy outcome.DESIGN: All poor attenders and a sample of good attenders were compared within three groups of women: women < 20 years, French women > or = 20 years, and foreigners > o... | ['Adolescent', 'Adult', 'Appointments and Schedules', 'Female', 'France', 'Health Services Accessibility', 'Humans', 'Patient Acceptance of Health Care', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Prenatal Care', 'Quality of Health Care', 'Risk Factors'] | 9,876,361 | [['M01.060.057'], ['M01.060.116'], ['N04.452.095'], ['Z01.542.286'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['G08.686.784.769'], ['C13.703'], ['E01.789.700', 'G08.686.784.769.496'], ['E02.760.786', 'N02.... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Detection of type III collagen fragments in specimens of abdominal aortic aneurysms. | The purpose of this study was to analyze the collagens in aortic aneurysm walls and to investigate the mechanism of the formation of calcified abdominal aortic aneurysms (AAAs). Collagens were extracted from human aneurysmal aortic walls obtained during surgery, and from human nonaneurysmal aortic walls obtained at aut... | ['Aortic Aneurysm, Abdominal', 'Aortic Diseases', 'Calcinosis', 'Collagen', 'Electrophoresis', 'Humans', 'Immunoblotting', 'Peptide Fragments'] | 9,590,702 | [['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.109'], ['C18.452.174.130'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.644.541']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical characteristics of non-steroidal anti-inflammatory drugs associated gastroduodenal ulcer bleeding]. | OBJECTIVE: To study the clinical characteristics of non-steroidal anti-inflammatory drugs (NSAIDs) associated gastroduodenal ulcer bleeding.METHODS: Patients who were hospitalized in our ward because of gastroduodenal bleeding from Jan, 1997 to Dec, 2001 were divided into two groups according to consumption of NSAIDs o... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Anti-Inflammatory Agents, Non-Steroidal', 'Duodenal Ulcer', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Middle Aged', 'Peptic Ulcer Hemorrhage', 'Sex Factors', 'Stomach Ulcer'] | 12,887,811 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.50... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Artifacts detection-based adaptive filtering to noise reduction of strain imaging. | Strain imaging in medical ultrasound is the imaging modality of elastic properties of biological tissue. In general, strain image will suffer from artifacts noise, which degrades lesion detectability and increases the likelihood of misdiagnosis. How to both suppress artifacts effectively and preserve the structure is v... | ['Algorithms', 'Artifacts', 'Image Processing, Computer-Assisted', 'Phantoms, Imaging', 'Signal-To-Noise Ratio', 'Ultrasonography'] | 31,238,255 | [['G17.035', 'L01.224.050'], ['E05.047'], ['L01.224.308'], ['E07.671'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750'], ['E01.370.350.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Membrane segment organization in the stator complex of the flagellar motor: implications for proton flow and proton-induced conformational change. | MotA and MotB are membrane proteins that form the stator of the bacterial flagellar motor. Each motor contains several MotA 4MotB 2 complexes, which function independently to conduct protons across the membrane and couple proton flow to rotation. The mechanism of rotation is not understood in detail but is thought to i... | ['Amino Acid Sequence', 'Cellular Structures', 'Cross-Linking Reagents', 'Escherichia coli', 'Escherichia coli Proteins', 'Flagella', 'Membrane Proteins', 'Membranes', 'Models, Biological', 'Molecular Motor Proteins', 'Molecular Sequence Data', 'Protein Conformation', 'Protons', 'Sequence Homology, Amino Acid'] | 18,834,143 | [['G02.111.570.060', 'L01.453.245.667.060'], ['A11.284'], ['D27.720.470.410.210'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['A11.284.180.290'], ['D12.776.543'], ['A10.615'], ['E05.599.395'], ['D05.500.500', 'D08.811.277.040.025.193'], ['L01.453.245.667'], ['G02.111.570.820.709'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Regulation of Kalirin by Cdk5. | Kalirin, one of the few Rho guanine nucleotide exchange factors (GEFs) that contains spectrin-like repeats, plays a critical role in axon extension and maintenance of dendritic spines. PC12 cells were used to determine whether Cdk5, a critical participant in both processes, regulates the action of Kalirin. Expression o... | ['Animals', 'Aspartic Acid', 'Cells, Cultured', 'Cyclin-Dependent Kinase 5', 'Dendritic Spines', 'Guanine Nucleotide Exchange Factors', 'Models, Biological', 'PC12 Cells', 'Phosphorylation', 'Protein Phosphatase 1', 'Rats', 'Threonine'] | 18,628,310 | [['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['A11.251'], ['D08.811.913.696.620.682.700.646.500.500.500', 'D12.644.360.250.067.875', 'D12.776.167.200.067.875', 'D12.776.476.250.067.875'], ['A08.675.256.200', 'A11.284.180.225.169', 'A11.671.240.169'], ['D12.644.360.325.300', 'D12.776.476.325.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TNF-alpha induced p21(WAF1) but not Bax in colon cancer cells WiDr with mutated p53: important role of protein stabilization. | The p21(WAF1)induces cell cycle arrest at G(1)and its expression is regulated by the functional p53. TNF-alpha induced expression of p21(WAF1)at protein and mRNA levels in a dose-dependent fashion with an association with G(1)-arrest in human colon cancer cells WiDr that carry mutated p53 at codon 273 (His(273)). Howev... | ['Apoptosis', 'Binding Sites', 'Blotting, Western', 'Cell Nucleus', 'Colonic Neoplasms', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclins', 'Cycloheximide', 'DNA', 'DNA, Complementary', 'Dose-Response Relationship, Drug', 'Flow Cytometry', 'G1 Phase', 'Genes, p53', 'Histidine', 'Humans', 'Luciferases', 'Mutation', 'Pl... | 11,097,743 | [['G04.146.954.035'], ['G02.111.570.120'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.46... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional analysis of the factor IX epidermal growth factor-like domain mutation Ile66Thr associated with mild hemophilia B. | The present study focused on the functional role of the mutation Ile66Thr located in the N-terminal epidermal growth factor-like domain of coagulation factor IX (FIX). This mutation causes mild hemophilia B with approximately 25% FIX coagulant activity and FIX antigen levels of around 90% of normal. In the 3-dimensiona... | ['Epidermal Growth Factor', 'Factor IX', 'Factor VIIIa', 'Factor X', 'Hemophilia B', 'Humans', 'Models, Molecular', 'Mutation, Missense', 'Protein Binding'] | 17,230,038 | [['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.622.355', 'D12.776.124.125.375', 'D12.776.811.243.355', 'D23.119.375'], ['D12.776.124.125.350.300', 'D23.119.350.300'], ['D08.622.471', 'D12.776.124.125.400', 'D12.776.811.243.471', 'D23.119.400'], ['C15.378.100.100.510', 'C15.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The critical-reflexive teaching-learning process]. | This study aimed at showing how the learning process is being built in the FAMEMA nursing course and identifying the different aspects of this process perceived by students based on the logics of the political-pedagogical project. The subjects of the research were fourth-grade students in the course. Research technique... | ['Education, Nursing', 'Problem Solving'] | 15,782,709 | [['I02.358.462'], ['F02.463.425.725', 'F02.463.785.810']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Should lymph nodes from colorectal cancer resection specimens be processed in their entirety? | AIMS: To quantify the benefit of processing each lymph node in its entirety in colorectal cancer specimens.METHODS: 391 consecutive cases were examined retrospectively to assess how often cases were upstaged to node positive disease by examining each node in its entirety.RESULTS: 7 out of 391 patients were upstaged by ... | ['Aged', 'Aged, 80 and over', 'Colorectal Neoplasms', 'Humans', 'Lymph Node Excision', 'Lymph Nodes', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies', 'Specimen Handling'] | 22,011,451 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.55... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social support and psychological adjustment among Latinas with arthritis: a test of a theoretical model. | BACKGROUND: Among people coping with chronic illness, tangible social support sometimes has unintended negative consequences on the recipient's psychological health. Identity processes may help explain these effects. Individuals derive self-worth and a sense of competence by enacting social roles that are central to th... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthritis, Rheumatoid', 'Factor Analysis, Statistical', 'Female', 'Hispanic Americans', 'Housekeeping', 'Humans', 'Middle Aged', 'Models, Psychological', 'New York City', 'Regression Analysis', 'Role', 'Self Concept', 'Se... | 15,184,092 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['M01.686.754.441'], ['N02.508']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Assessment of the effect of cigarette smoking on regional brain volumes and lesion load in patients with clinically isolated syndrome. | PURPOSE: Smoking has been associated with an increased risk of developing multiple sclerosis, disease progression and clinical disability. We detected the effects of smoking on regional brain volumes and lesion load in patients with clinically isolated syndrome using quantitative magnetic resonance imaging.MATERIALS AN... | ['Adult', 'Atrophy', 'Cross-Sectional Studies', 'Demyelinating Diseases', 'Female', 'Gray Matter', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Smoking', 'White Matter', 'Young Adult'] | 26,268,999 | [['M01.060.116'], ['C23.300.070'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C10.314'], ['A08.186.211.168', 'A08.186.854.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['F01.145.805'], ['A08.186.211.204', 'A08.186.854.880'], ['M01.060.116.815']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Setup accuracy of stereotactic body radiation therapy (SBRT) using virtual isocenter in image-guided radiation therapy (IGRT)]. | We use Novalis Body system for stereotactic body radiation therapy (SBRT) in lung and liver tumors. Novalis system is dedicated to SBRT with image-guided patient setup system ExacTrac. The spinal bone is the main landmark in patient setup during SBRT using ExacTrac kV X-ray system. When the target tumor is located late... | ['Humans', 'Liver Neoplasms', 'Lung Neoplasms', 'Phantoms, Imaging', 'Radiosurgery', 'Radiotherapy, Image-Guided'] | 23,089,838 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E07.671'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['E02.815.768']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Menefee model for patient-focused interdisciplinary team collaboration. | The conversion to electronic plans of care in a community hospital setting offered an opportunity to design an interdisciplinary, collaborative model for patient-focused care. The performance improvement initiative began with the development of evidence-based interdisciplinary plans of care and concluded with a consist... | ['Cooperative Behavior', 'Electronic Health Records', 'Hospitals, Community', 'Humans', 'Interdisciplinary Communication', 'Interprofessional Relations', 'Models, Nursing', 'Nursing Evaluation Research', 'Nursing Staff, Hospital', 'Patient Care Planning', 'Patient Care Team', 'Program Evaluation'] | 25,340,925 | [['F01.145.813.115'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['N02.278.421.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['F01.829.401.205'], ['E05.599.645'], ['H01.770.644.14... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
On the evolution of the terminal redundancies of Klebsiella phage No. 11 and of coliphages T3 and T7. | The phylogenetic relationship between Klebsiella phage No. 11 and the classical coliphages T7 and T3, postulated in a previous study, was investigated at the nucleotide level by sequencing the termini of phage No. 11 DNA. This DNA was found to have a terminal redundancy of 181 base pairs. Comparison of the terminal seq... | ['Bacteriophages', 'Base Sequence', 'Coliphages', 'DNA, Viral', 'Klebsiella'] | 3,968,536 | [['B04.123'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.123.205'], ['D13.444.308.568'], ['B03.440.450.425.425', 'B03.660.250.150.400']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Heartbeat Wales--a community programme. | Heartbeat Wales is a broadly based initiative designed to decrease the incidence of cardiovascular disease. After three years there are encouraging signs that the people of the Principality are adopting a healthier lifestyle. | ['Cardiovascular Diseases', 'Health Promotion', 'Humans', 'Wales'] | 2,587,503 | [['C14'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.363.914']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Use of sexed sorted semen for fixed-time artificial insemination or fixed-time embryo transfer of in vitro-produced embryos in cattle. | Artificial insemination and in vitro embryo production are powerful tools for disseminating superior genetic qualities and improving the reproductive performance of dairy and beef cattle. In conjunction with these biotechnologies, sexed-sorted semen has been used to obtain offspring of a predetermined sex. This study c... | ['Animals', 'Cattle', 'Embryo Transfer', 'Female', 'In Vitro Oocyte Maturation Techniques', 'Insemination, Artificial', 'Male', 'Pregnancy', 'Sex Preselection'] | 27,068,357 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.906', 'E05.820.800.906'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['G08.686.784.769'], ['E05.393.420.890']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ethnic differences in the sudden infant death syndrome: what we can learn from immigrants to the UK. | AIMS: To compare the effect of potential maternal and birth factors on rates of sudden infant death syndrome (SIDS) within and between infants born to mothers of different ethnic groups.METHODS: Routinely collected obstetric, child health data relating to 39,101 residents of three East London Districts born in 1989-199... | ['Africa', 'Asia', 'Bangladesh', 'Europe', 'Female', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Male', 'Pregnancy', 'Prevalence', 'Risk Factors', 'Smoking', 'Sudden Infant Death', 'United Kingdom', 'West Indies'] | 7,821,257 | [['Z01.058'], ['Z01.252'], ['Z01.252.245.131'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['G08.686.784.769'], ['E05.318.30... | ['Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Probing essential water in yeast pyrophosphatase by directed mutagenesis and fluoride inhibition measurements. | The pattern of yeast pyrophosphatase (Y-PPase) inhibition by fluoride suggests that it replaces active site Mg(2+)-bound nucleophilic water, for which two different locations were proposed previously. To localize the bound fluoride, we investigate here the effects of mutating Tyr(93) and five dicarboxylic amino acid re... | ['Amino Acid Substitution', 'Binding Sites', 'Diphosphates', 'Fluorides', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Inorganic Pyrophosphatase', 'Kinetics', 'Magnesium', 'Models, Chemical', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Mutation', 'Protein Binding', 'Pyrophosphatases', 'Water', 'Yeasts'] | 11,031,269 | [['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.120'], ['D01.029.260.700.675.374.775.150', 'D01.248.497.158.730.650.200', 'D01.695.625.675.650.775.150'], ['D01.248.497.158.380', 'D01.303.350.300'], ['G02.300'], ['G02.380'], ['D08.811.277.040.600.399', 'D12.776.157.530.450.250.875.487', 'D12.776.543.585.450.250.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The low rate of HIV infection in Japanese homosexual and bisexual men: an analysis of HIV seroprevalence and behavioural risk factors. | OBJECTIVE: To assess the seroprevalence of HIV-1 infection in homosexual and bisexual men in Nagoya City, Japan.DESIGN: A prospective study ongoing since April 1986.METHODS: Nine hundred and thirty-eight serum samples were collected from 531 participants in August 1990 in an anonymous, confidential testing programme. A... | ['Adolescent', 'Adult', 'Aged', 'Bisexuality', 'HIV Seroprevalence', 'Homosexuality', 'Humans', 'Interviews as Topic', 'Japan', 'Male', 'Middle Aged', 'Prospective Studies', 'Risk Factors', 'Risk-Taking', 'Telephone'] | 1,616,657 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.802.975.200', 'G08.686.867.200'], ['E05.318.372.500.950.375', 'N05.715.360.330.500.950.375', 'N06.850.520.450.500.950.375'], ['F01.145.802.975.500', 'G08.686.867.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Epidural spinal cord compression in a patient with blue rubber bleb nevus syndrome. | Blue rubber bleb nevus syndrome (BRBNS) can present with vascular malformations throughout the body, especially in the gastrointestinal tract. Spinal cord compression from these lesions is rare, particularly in the pediatric population. The authors report a case of BRBNS involving an 18-year-old female patient who pres... | ['Adolescent', 'Decompression, Surgical', 'Female', 'Gastrointestinal Neoplasms', 'Humans', 'Laminectomy', 'Nevus, Blue', 'Skin Neoplasms', 'Spinal Cord Compression', 'Thoracic Vertebrae', 'Treatment Outcome'] | 25,238,626 | [['M01.060.057'], ['E04.188'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['C04.557.665.560.615.550'], ['C04.588.805', 'C17.800.882'], ['C10.228.854.761', 'C26.819.678'], ['A02.835.232.834.892'], ['E01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Modafinil for the treatment of attention-deficit/hyperactivity disorder: A meta-analysis. | Attention-deficit/hyperactivity disorder (ADHD) is one of the most common and a debilitating neuro-behavior disorder in the pediatric population. Although numerous effective psychostimulants are available, more than 30% of patients still do not show adequate treatment response rendering diverse pharmacological options.... | ['Adolescent', 'Attention Deficit Disorder with Hyperactivity', 'Benzhydryl Compounds', 'Central Nervous System Stimulants', 'Child', 'Humans', 'Modafinil', 'Psychotropic Drugs', 'Randomized Controlled Trials as Topic'] | 27,810,669 | [['M01.060.057'], ['F03.625.094.150'], ['D02.455.426.559.389.115'], ['D27.505.696.282', 'D27.505.954.427.220'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.115.550'], ['D27.505.954.427.700'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pluripotency: capacity for in vitro differentiation of undifferentiated embryonic stem cells. | Embryonic stem (ES) cells, the pluripotent cells of early embryos have been successfully cultured as undifferentiated cells. The cells are characterized by two unique properties, unlimited self-renewal capacity and the ability to differentiate into all cells of the body. Because of the high in vitro differentiation pot... | ['Animals', 'Cell Adhesion', 'Cell Culture Techniques', 'Cell Differentiation', 'Culture Media', 'Embryo, Mammalian', 'Enzyme-Linked Immunosorbent Assay', 'Liver', 'Mice', 'Myocytes, Cardiac', 'Neurons', 'Pancreas', 'Stem Cells'] | 16,761,727 | [['B01.050'], ['G04.022'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['D27.720.470.305', 'E07.206'], ['A16.254'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A03.620'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behaviour of surface acoustic wave interdigitated array electrode sensor in non-aqueous solution and determination of blood plasma recalcification time. | A novel SAW-IDA sensor system was constructed for the first time by connecting the IDA electrodes in series with a SAW resonator. The frequency characteristics of the SAW-IDA sensor in non-aqueous solution were investigated. The effects of the parallel capacitance and cell constant were studied, and were calculated wit... | ['Acoustic Stimulation', 'Blood Coagulation Tests', 'Electrodes', 'Humans', 'Partial Thromboplastin Time', 'Solutions', 'Surface Properties'] | 8,729,241 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['E01.370.225.625.115', 'E05.200.625.115'], ['E07.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.600', 'E05.200.625.115.600', 'G09.188.660'], ['D26.776'], ['G02.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Continuous measurement of left ventricular volume using a single dimensional transducer: a comparison of two techniques in open chested dogs. | A comparison has been made of the continuous measurement of left ventricular volume in open chested dogs by two simple dimensional transducer systems: a mercury-in-rubber strain gauge measuring epicardial arc length at the ventricular equator and a pair of electromagnetically coupled coils placed on opposite sides of t... | ['Animals', 'Cardiac Volume', 'Dogs', 'Electromagnetic Phenomena', 'Mercury', 'Transducers', 'Ventricular Function'] | 1,175,179 | [['B01.050'], ['G09.330.380.249'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.358.500'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['E07.305.812'], ['G09.330.955']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phase I study of twelve-day prolonged infusion of high-dose ifosfamide and doxorubicin as first-line chemotherapy in adult patients with advanced soft tissue sarcomas. | PURPOSE: To determine whether a prolonged 12-day continuous infusion allows the administration of high-dose ifosfamide (IFO) with an acceptable toxicity profile when combined with full-dose doxorubicin (Adriamycin; ADM) as first-line chemotherapy in patients with advanced soft tissue sarcomas.PATIENTS AND METHODS: Esca... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Disease Progression', 'Dose-Response Relationship, Drug', 'Doxorubicin', 'Female', 'Humans', 'Ifosfamide', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Sarcoma', 'Time Factors', 'Treatment Outcome'] | 11,863,099 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C23.550.291.656'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.728... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Micromultiplane transesophageal echocardiographic probe for intraoperative study of congenital heart disease repair in neonates, infants, children, and adults. | This study reports the development of a micromultiplane 8.2-mm transesophageal echocardiographic probe. The probe is applicable to newborn infants and can deliver diagnostic images in adults. | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Echocardiography, Transesophageal', 'Equipment Design', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Infant, Newborn', 'Intraoperative Period'] | 10,073,843 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E05.320'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E04.614.374... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hepatitis B virus X protein upregulates DNA methyltransferase 3A/3B and enhances SOCS-1CpG island methylation. | The aim of the present study was to investigate the effect of hepatitis B virus X protein (HBx) on the expression of DNA methyltransferase (DNMT)3A/3B and suppressors of cytokine signaling‑1 (SOCS‑1), as well as promoter CpG island methylation of the SOCS‑1 gene. Stable hepatocyte cell lines expressing the HBx gene (pc... | ['Blotting, Western', 'Cell Line', 'CpG Islands', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Methylation', 'Humans', 'Immunohistochemistry', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Suppressor of Cytokine Signaling 1 Protein', 'Suppressor of Cytokine Signaling Proteins', 'Trans-Activators', 'Transfec... | 26,573,490 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D08.811.913.555.500.350.100.500'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['B01.050.150.900.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
BP‑1‑102 exerts an antitumor effect on the AGS human gastric cancer cell line through modulating the STAT3 and MAPK signaling pathways. | BP‑1‑102, a novel inhibitor of signal transducer and activator of transcription 3 (STAT3), exhibits significant antitumor effects in several malignancies in vitro and in vivo. However, its role in gastric cancer (GC) remains to be elucidated. In the present study, the effect and potential molecular mechanisms of BP‑102... | ['Aminosalicylic Acids', 'Antineoplastic Agents', 'Apoptosis', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Humans', 'Mitogen-Activated Protein Kinases', 'STAT3 Transcription Factor', 'Signal Transduction', 'Stomach Neoplasms', 'Sulfonamides'] | 30,720,080 | [['D02.241.223.100.300.595.100', 'D02.241.511.390.595.100', 'D02.455.426.559.389.127.281.595.100', 'D02.455.426.559.389.657.410.595.100'], ['D27.505.954.248'], ['G04.146.954.035'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of prematurely condensed chromosomes from testicular cells of the mouse. | Mitotic CHO cells and mouse testicular cells were fused with polyethylene glycol. Several types of prematurely condensed chromosomes were observed. From chromosome morphology it was possible to determine that most of the PCC represented mouse cells. Labeling of either the CHO cells in vitro or the testicular cells in v... | ['Animals', 'Cell Fusion', 'Cell Line', 'Chromosomes', 'Cricetinae', 'Cricetulus', 'Female', 'Haplorhini', 'Male', 'Mice', 'Mitosis', 'Ovary', 'Testis', 'Thymidine', 'Tritium'] | 117,994 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of prenatal ethanol exposure on rat brain radial glia and neuroblast migration. | Prenatal ethanol exposure (PEE) induces morphologic and functional alterations in the developing central nervous system. The orderly migration of neuroblasts is a key process in the development of a layered structure such as the cerebral cortex (CC). From initial stages of corticogenesis, the transcription factor Pax6 ... | ['Analysis of Variance', 'Animals', 'Brain', 'Cell Movement', 'Ethanol', 'Eye Proteins', 'Female', 'Fluorescent Antibody Technique', 'Homeodomain Proteins', 'Immunohistochemistry', 'Intermediate Filament Proteins', 'Microtubule-Associated Proteins', 'Nerve Tissue Proteins', 'Nestin', 'Neuroglia', 'Neurons', 'Neuropepti... | 21,414,313 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.186.211'], ['G04.198', 'G07.568.500.180'], ['D02.033.375'], ['D12.776.306'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['D12.776.260.400']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhancing excitatory activity of somatosensory cortex alleviates neuropathic pain through regulating homeostatic plasticity. | Central sensitization and network hyperexcitability of the nociceptive system is a basic mechanism of neuropathic pain. We hypothesize that development of cortical hyperexcitability underlying neuropathic pain may involve homeostatic plasticity in response to lesion-induced somatosensory deprivation and activity loss, ... | ['Action Potentials', 'Animals', 'Behavior, Animal', 'Channelrhodopsins', 'Disease Models, Animal', 'Excitatory Postsynaptic Potentials', 'Homeostasis', 'Hyperalgesia', 'Inhibitory Postsynaptic Potentials', 'Ischemia', 'Mice, Inbred C57BL', 'Neuralgia', 'Neuronal Plasticity', 'Optogenetics', 'Pyramidal Cells', 'Somatos... | 28,986,567 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F01.145.113'], ['D12.776.157.530.400.163', 'D12.776.543.550.450.163', 'D12.776.543.585.400.163', 'D12.776.765.593.250'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.91... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mid-term results of revision total hip arthroplasty with an uncemented modular femoral component. | INTRODUCTION: During revision total hip arthroplasty (THA), the surgeon commonly faces deficient proximal femoral bone. In this situation, distal fixation of the prosthesis is required. The aim of the current retrospective study is to assess the clinical and radiographic mid-term outcome of revision total hip arthropla... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Female', 'Femur', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Periprosthetic Fractures', 'Prosthesis Design', 'Prosthesis Failure', 'Reoperation', 'Retrospective Studies', 'Treatment Outcome'] | 29,027,190 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['A02.835.232.043.150'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C26.404.550'], ['E05.320.550', 'E07.695.680'], ['C23.550.767.865', 'E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. | The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not fully understood. In D. melanogaster, RB-dependent repression is mediated in part by the multisubunit protein complex Drosophila RBF, E2F, and Myb (dREAM) that contains homologs of the C. el... | ['Animals', 'Caenorhabditis elegans', 'Cell Cycle', 'Cellular Senescence', 'Conserved Sequence', 'Crk-Associated Substrate Protein', 'Drosophila melanogaster', 'E2F4 Transcription Factor', 'Evolution, Molecular', 'Gene Deletion', 'Gene Expression Regulation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kv Chan... | 17,531,812 | [['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['G04.144'], ['G04.043'], ['G02.111.570.580'], ['D12.644.360.024.282', 'D12.776.157.057.016', 'D12.776.476.024.316', 'D12.776.744.425'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D12.776.930.211.812'], ['G05.045.250', 'G16.075.250'], ['G05.365.590.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The plasma membrane of yeast protoplasts exposed to hypotonicity becomes porous but does not disintegrate in the presence of protons or polyvalent cations. | Protoplasts of Saccharomyces cerevisiae swelled, lysed and disintegrated when exposed to hypotonic solutions at neutral pH. At pH 4.5 or lower the hypotonically treated protoplasts did not disintegrate and they retained their intracellular proteins, nucleic acids and nucleotides. However, they became leaky for K+ and C... | ['Cell Membrane', 'Freeze Etching', 'Hydrogen-Ion Concentration', 'Hypotonic Solutions', 'Indicators and Reagents', 'Microscopy, Electron', 'Protoplasts', 'Saccharomyces cerevisiae'] | 3,555,618 | [['A11.284.149'], ['E01.370.225.500.620.620.260.400', 'E01.370.225.750.600.620.260.400', 'E05.200.500.620.620.260.400', 'E05.200.750.600.620.260.400'], ['G02.300'], ['D26.776.399'], ['D27.720.470.410'], ['E01.370.350.515.402', 'E05.595.402'], ['A11.789'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delaying virus maturation for a higher yield of cell associated virus antigens. | Negligible amounts of virus were released when infected cells were maintained in low ionic strength medium. The cells accumulated a high titre of virus and its specific antigenic proteins, detected by complement-fixation test. The procedure has potential for production of virus subunit vaccines. | ['Animals', 'Antigens, Viral', 'Cell Line', 'Complement Fixation Tests', 'Culture Media', 'Dengue Virus', 'Encephalitis Virus, Japanese', 'Encephalitis Virus, St. Louis', 'Epitopes', 'Flavivirus', 'West Nile virus'] | 2,481,802 | [['B01.050'], ['D23.050.327'], ['A11.251.210'], ['E01.370.225.812.735.150', 'E05.200.812.735.150', 'E05.478.594.760.150'], ['D27.720.470.305', 'E07.206'], ['B04.820.578.344.350.270'], ['B04.820.230.475.227', 'B04.820.578.344.350.300.227'], ['B04.820.230.475.330', 'B04.820.578.344.350.300.330'], ['D23.050.550'], ['B04.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms. | The role of dopamine D3 receptors was investigated in mediating the neuroprotective effect of the dopamine D2/D3 receptor agonist (S)-2-amino-4,5,6,7-tetrahydro-6-propylamine-benzothiazole (pramipexole) in vivo. Pramipexole retained the ability to inhibit 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopa... | ['Animals', 'Benzothiazoles', 'Dopamine', 'Dopamine D2 Receptor Antagonists', 'Dose-Response Relationship, Drug', 'MPTP Poisoning', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Piperazines', 'Pramipexole', 'Pyrimidines', 'Receptors, Dopamine D2', 'Receptors, Dopamine D3', 'Thiazoles'] | 12,954,356 | [['B01.050'], ['D03.383.129.708.089', 'D03.633.100.185'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D27.505.519.625.150.175.500', 'D27.505.696.577.150.175.500'], ['G07.690.773.875', 'G07.690.936.500'], ['C10.228.140.079.862.800.300', 'C10.228.662.600.700.250', 'C10.720.606', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.