Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish. | Dorsal retinal fate is established early in eye development, via expression of spatially restricted dorsal-specific transcription factors in the optic vesicle; yet the events leading to initiation of dorsal fate are not clear. We hypothesized that induction of dorsal fate would require an extraocular signal arising fro... | ['Animals', 'Bone Morphogenetic Protein 2', 'Cell Differentiation', 'DNA Primers', 'Ectoderm', 'Eye', 'Gene Expression Regulation, Developmental', 'Genotype', 'Growth Differentiation Factor 6', 'In Situ Hybridization', 'Morphogenesis', 'Polymerase Chain Reaction', 'Pyrazoles', 'Pyrimidines', 'Retina', 'Zebrafish', 'Zeb... | 22,921,921 | [['B01.050'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['G04.152'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A16.504.273'], ['A01.456.505.420', 'A09.371'], ['G05.308.310'], ['G05.380'], ['D12.644.276.954.300.600', 'D12.776.467.942.300.600', 'D23.529.942.300.600... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[MADEsmart: a web-based system for accessing data and healthcare indicators]. | Methods for accessing information have evolved making thus possible the planning of a new generation of web applications. In the Piemonte region, tools for accessing demographic data and main health and epidemiologic indicators are available since several years. A new application named MADEsmart (from the Italian for "... | ['Computer Systems', 'Databases, Factual', 'Demography', 'Female', 'Health Services', 'Health Status Indicators', 'Hospitalization', 'Humans', 'Internet', 'Italy', 'Male', 'Mortality', 'Quality Indicators, Health Care', 'Regional Health Planning', 'Software'] | 19,219,083 | [['L01.224.230'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['N02.421'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.... | ['Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
The economics of clinical genetics services. III. Cognitive genetics services are not self-supporting. | We investigated the amount of time required to provide, and the charges and reimbursement for, cognitive genetics services in four clinical settings. In a prenatal diagnostic center, a mean of 3 h/couple was required to provide counseling and follow-up services with a mean charge of $30/h and collection of $27/h. Only ... | ['Costs and Cost Analysis', 'Fees and Charges', 'Genetic Counseling', 'Genetics, Medical', 'Maryland', 'Task Performance and Analysis'] | 2,912,071 | [['N03.219.151'], ['N03.219.442'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['H01.158.273.343.385.500', 'H02.403.350'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Strontium promotes cell proliferation and suppresses IL-6 expression in human PDL cells. | This study was designed to investigate the effect of strontium on human PDL cells in vitro. Strontium is used to treat osteoporosis because of its bone formation promoting effect on osteoblast cells. This investigation presents evidence that strontium promotes PDL cell proliferation. Simultaneously, strontium suppresse... | ['Adolescent', 'Cell Proliferation', 'Cells, Cultured', 'Female', 'Guided Tissue Regeneration, Periodontal', 'Humans', 'Interleukin-6', 'Osteoblasts', 'Periodontal Ligament', 'RNA', 'Real-Time Polymerase Chain Reaction', 'Strontium'] | 22,051,238 | [['M01.060.057'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['E04.680.300.500', 'E06.645.410', 'E06.721.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['A11.329.629'], ['A14.549.167.646.771'], ['D13.444.735'], ['E05.393.6... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hydraulic water permeability and transepithelial voltage in the isolated perfused rabbit cortical collecting tubule following acute unilateral ureteral obstruction. | Ureteral obstruction affects the kidney's ability to conserve water and sodium. Using the isolated perfused tubule technique, we studied cortical collecting tubules (CCT) taken from rabbits subjected to a sham operation or to 4 h of unilateral ureteral obstruction (UUO). Tubules were perfused in the presence of an osmo... | ['Adrenal Cortex Hormones', 'Animals', 'Bucladesine', 'Electric Conductivity', 'Female', 'Kidney Tubules', 'Kidney Tubules, Collecting', 'Osmotic Pressure', 'Prostaglandins', 'Rabbits', 'Ureteral Obstruction', 'Vasopressins', 'Water-Electrolyte Balance'] | 2,981,250 | [['D06.472.040'], ['B01.050'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['G01.358.500.249.277'], ['A05.810.453.736.560'], ['A05.810.453.736.560.510'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['D10.251.355.255.550', 'D23.469.050.175.725'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of des-aspartate-angiotensin I on neointima growth and cardiovascular hypertrophy. | The in vitro anti-hypertrophic and hyperplastic actions of des-aspartate-angiotensin I (DAA-I) on cultured cardiovascular cells have been demonstrated in earlier experiments. The present study investigated its effects on the development of neointima in balloon catheter-injured carotid artery of the Sprague-Dawley (SD) ... | ['Angiotensin I', 'Angiotensin III', 'Animals', 'Arterial Occlusive Diseases', 'Arteriosclerosis', 'Cardiomegaly', 'Cardiomyopathy, Hypertrophic', 'Dose-Response Relationship, Drug', 'Hypertension', 'Injections, Intravenous', 'Male', 'Rats', 'Tunica Intima'] | 14,749,042 | [['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['D06.472.699.094.080', 'D12.644.400.070.080', 'D12.644.456.073.055', 'D12.644.548.058.080', 'D12.776.631.650.070.080', 'D23.469.050.050.075'], ['B01.050'], ['C14.907.137'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism. | Changes in systemic redox balance can alter platelet activation and aggregation. Acute pulmonary embolism (PE) is a systematic inflammatory disease associated with mechanical shear stress, increased thrombin, catecholamines, serotonin and hemolysis, which cumulatively can hyperactivate platelets and accelerate their tu... | ['Acute Disease', 'Adult', 'Aged', 'Apoptosis', 'Blood Coagulation', 'Blood Platelets', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mitochondria', 'Oxidative Stress', 'Platelet Activation', 'Pulmonary Embolism', 'Reactive Oxygen Species', 'Thrombophilia'] | 28,528,289 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['G04.146.954.035'], ['G09.188.390.150'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G03.673', 'G07.775.750'], ['G09.188.390.600'], ['C08.381.7... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Age-related differences in parameters of vestibular evoked myogenic potentials. | CONCLUSIONS: The statistically significant correlations between vestibular evoked myogenic potential (VEMP) parameters and age may be due to hair cell loss of the otolith organ and/or to degenerative changes of the vestibular neural pathway. These findings indicate that age should be taken into account when interpretin... | ['Acoustic Maculae', 'Acoustic Stimulation', 'Adolescent', 'Adult', 'Aged', 'Aging', 'Child', 'Dominance, Cerebral', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motor Neurons', 'Neck Muscles', 'Reaction Time', 'Reference Values', 'Signal Processing, Computer-Assisted', 'S... | 17,851,962 | [['A09.246.300.909.625.125'], ['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['M01.060.406'], ['F02.830.297', 'G11.561.225'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
pH Sensitive graft copolymers for zero order drug release: a mechanistic analysis. | Aliphatic polyesters containing pendent unsaturation were synthesized by the polycondensation of a diol, dicarboxylic acid and glycidyl methacrylate. Grafting methacrylic acid (MAA) resulted in graft copolymers containing polyester backbone and MAA grafts. Depending on composition, the polymers swelled extensively and ... | ['Chemistry, Pharmaceutical', 'Delayed-Action Preparations', 'Dicarboxylic Acids', 'Diffusion', 'Diltiazem', 'Dosage Forms', 'Epoxy Compounds', 'Hydrogen-Ion Concentration', 'Indomethacin', 'Methacrylates', 'Microspheres', 'Particle Size', 'Pharmacokinetics', 'Polyesters', 'Polymers', 'Solubility', 'Tablets', 'Verapami... | 22,118,221 | [['H01.158.703.007', 'H01.181.466'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.081.337'], ['G01.202', 'G02.196'], ['D03.633.100.079.150'], ['D26.255', 'E05.916.250'], ['D02.355.291.411'], ['G02.300'], ['D03.633.100.473.420'], ['D02.241.081.069.600'], ['E07.565'], ['G02.712'], ['G03.787', 'G07.690.725'], ['D05.750.7... | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Tremor magnitude: a single index to assess writing and drawing in essential tremor. | Hand tremor often causes disability in patients with essential tremor (ET). Aim of the study was to investigate whether tremor magnitude, a new single quantitative score obtained from digital tablet recordings of writing and drawing, is able to adequately reflect disability in ET patients. Mean tremor magnitude values ... | ['Adult', 'Aged', 'Case-Control Studies', 'Essential Tremor', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychomotor Performance', 'Severity of Illness Index', 'Statistics, Nonparametric', 'Writing'] | 16,793,316 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.228.662.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A qualitative study of perceptions of meaningful change in spinal muscular atrophy. | BACKGROUND: This qualitative study examined how individuals with Spinal Muscular Atrophy (SMA), their caregivers, and clinicians defined meaningful change, primarily in the Type II and non-ambulant type III patient populations, associated with treatment of this condition. In addition, we explored participants' views ab... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Health Personnel', 'Humans', 'Infant', 'Male', 'Muscular Atrophy, Spinal', 'Parents', 'Patient Reported Outcome Measures', 'Qualitative Research', 'Quality of Life', 'Young Adult'] | 28,376,816 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C10.228.854.468', 'C10.574.562.500', 'C10.668.467.500'], ['F01.829.263.500.32... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
PKIB promotes cell proliferation and the invasion-metastasis cascade through the PI3K/Akt pathway in NSCLC cells. | Lung cancer is one of the most common malignancies in the world, and non-small cell lung cancer (NSCLC) is a major subtype of lung cancer. Overgrowth of tumor cells usually results from the intensive proliferation of cancer cells, but the mechanisms by which the proliferation of cancer cells are promoted are currently ... | ['A549 Cells', 'Blotting, Western', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Proliferation', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Lung Neoplasms', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Phosphatidylinositol 3-Kinase', 'Proto-Oncogene Proteins c-akt', 'Real-Time Polyme... | 27,325,557 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Lateral Soft Tissue Release on Sesamoid Position in Hallux Valgus Surgery. | BACKGROUND: The effect of lateral soft tissue release (LSTR) regarding the position of the sesamoid is not clear. The purpose of this study was to evaluate the effect of LSTR by comparing the radiologic and clinical outcomes of operative treatment for hallux valgus with or without LSTR.METHODS: This study included a co... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Hallux Valgus', 'Humans', 'Joint Capsule', 'Ligaments, Articular', 'Male', 'Metatarsal Bones', 'Middle Aged', 'Orthopedic Procedures', 'Osteotomy', 'Radiography', 'Retrospective Studies', 'Sesamoid Bones', 'Tendons', 'Young Adult'] | 26,208,509 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.330.610'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.443'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['A02.835.232.043.300.492'], ['M01.060.116.630'], ['E02.718', 'E04.555'], ['E04.555.580'], ['E01.370.350.700'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors affecting participation in Sure Start programmes: a qualitative investigation of parents' views. | The objectives of the present study were to examine the factors that parents identify as promoting or hindering participation in Sure Start programmes, and to identify methods for enhancing parents' engagement with Sure Start. A qualitative, in-depth interview study was conducted with parents registered with two local ... | ['Community Participation', 'Humans', 'Parents', 'Qualitative Research', 'Social Work', 'United Kingdom', 'Urban Population'] | 17,444,983 | [['N02.421.143.212', 'N03.540.245.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['H01.770.644.241.850'], ['I01.880.792', 'N02.421.849'], ['Z01.542.363'], ['N01.600.900']] | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Energy consumption of paraplegic locomotion using reciprocating gait orthosis. | The energy cost of walking using a reciprocating gait orthosis (RGOII) with functional electrical stimulation (FES) was assessed in 14 patients with spastic complete paraplegia from six rehabilitation centres. Before and after training asing RGOII with FES, the subjects performed a progressive maximal test on an arm-cr... | ['Adult', 'Electric Stimulation', 'Energy Metabolism', 'Gait', 'Heart Rate', 'Humans', 'Lactic Acid', 'Locomotion', 'Orthotic Devices', 'Oxygen Consumption', 'Paraplegia'] | 8,781,872 | [['M01.060.116'], ['E05.723.402'], ['G03.295'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['G07.568.500', 'G11.427.410.568'], ['E07.858.442.743'], ['G03.680'], ['C10.597.622.669', 'C23.888.592.636... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A game of two? Gene expression analysis of brain (cyp19a1b) and gonadal (cyp19a1a) aromatase in females of a Neotropical cichlid fish through the parental care period and removal of the offspring. | For many species parental behavior is essential for the survival of the offspring. While the ultimate causes of teleost parental behavior have been widely studied, comparatively little is known about its proximate causes. The aim of this study was to analyze the yet unexplored, potential dual role of brain and gonadal ... | ['Animals', 'Aromatase', 'Behavior, Animal', 'Brain', 'Cichlids', 'Estradiol', 'Female', 'Fluorescence', 'Gene Expression Regulation, Enzymologic', 'Gonadal Steroid Hormones', 'Male', 'Ovary', 'Reproduction', 'Testosterone', 'Tropical Climate'] | 28,797,804 | [['B01.050'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['F01.145.113'], ['A08.186.211'], ['B01.050.150.900.493.602.200'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enantioselective degradation of metalaxyl in grape, tomato, and rice plants. | Enantioselective biodegradation of chiral pesticide metalaxyl in grape, tomato, and rice plants under field conditions were studied. Metalaxyl enantiomers were completely separated with a resolution (Rs) of 5.01 by high-performance liquid chromatography (HPLC) based on a cellulose tris (3-chloro-4-methyl phenyl carbama... | ['Acetonitriles', 'Alanine', 'Biodegradation, Environmental', 'Calibration', 'Chromatography, High Pressure Liquid', 'Fungicides, Industrial', 'Half-Life', 'Lycopersicon esculentum', 'Oryza', 'Reproducibility of Results', 'Solid Phase Extraction', 'Vitis'] | 25,311,959 | [['D02.626.080'], ['D12.125.042'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E05.978.155'], ['E05.196.181.400.300'], ['D27.720.031.700.288', 'D27.888.723.288'], ['G01.910.405'], ['B01.650.940.800.575.912.250.908.500.322'], ['B01.650.940.800.575.912.250.822.616'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The function and operation of a parent support association. | The use of a parent support organisation and its responsibilities and limitations are described. The difference between a parent support organisation and an association of limb deficient children is discussed. | ['Adult', 'Group Processes', 'Humans', 'Infant, Newborn', 'Limb Deformities, Congenital', 'Parents', 'Self-Help Groups'] | 1,923,722 | [['M01.060.116'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C05.660.585', 'C16.131.621.585'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['N03.540.782']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
MR imaging of intraventricular cysticercosis. | Intraventricular cysticercosis cysts can migrate through the ventricular system and produce hydrocephalus. MR is more sensitive than CT in the detection of these cysts. | ['Adult', 'Brain Diseases', 'Cerebral Ventricles', 'Cysticercosis', 'Humans', 'Magnetic Resonance Imaging', 'Male'] | 1,636,544 | [['M01.060.116'], ['C10.228.140'], ['A08.186.211.140'], ['C01.610.335.190.902.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A longitudinal study of time trends in the eruption of permanent teeth in Danish children. | The purpose was: (1) to estimate mean eruption times of permanent teeth in Danish schoolchildren for the birth cohorts from 1969 to 1982; and (2) to determine any time trends in eruption. For teeth with a low proportion of aplasia, the distribution of the eruption time was close to normal. For teeth with a higher propo... | ['Adolescent', 'Age Factors', 'Child', 'Denmark', 'Dentition, Permanent', 'Female', 'Humans', 'Likelihood Functions', 'Linear Models', 'Longitudinal Studies', 'Male', 'Time Factors', 'Tooth Eruption'] | 11,286,807 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['Z01.542.816.124'], ['A14.549.167.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.85... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Determination of butyl- and phenyltin compounds in human urine by HS-SPME after derivatization with tetraethylborate and subsequent determination by capillary GC with microwave-induced plasma atomic emission and mass spectrometric detection. | A headspace solid-phase micro-extraction (HS-SPME) method was developed and optimized for gas chromatographic separation and determination of commonly found organotin compounds in human urine after potential exposure. Butyl- and phenyltin compounds were in situ derivatized to ethylated derivatives by sodium tetraethylb... | ['Chromatography, Gas', 'Humans', 'Mass Spectrometry', 'Organotin Compounds', 'Solid Phase Extraction'] | 19,203,626 | [['E05.196.181.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D02.691.850'], ['E05.196.155.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Generation of Two-color Antigen Microarrays for the Simultaneous Detection of IgG and IgM Autoantibodies. | Autoantibodies, which are antibodies against self-antigens, are present in many disease states and can serve as markers for disease activity. The levels of autoantibodies to specific antigens are typically detected with the enzyme-linked immunosorbent assay (ELISA) technique. However, screening for multiple autoantibod... | ['Animals', 'Antigens', 'Autoantibodies', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Mice', 'Protein Array Analysis'] | 27,685,156 | [['B01.050'], ['D23.050'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.39... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endothelial serotonin uptake and mediation of prostanoid secretion and stress fiber formation. | The kinetics of serotonin (5-hydroxytryptamine [5-HT] ) uptake by intimal and microvessel endothelial cells (ECs), in culture and in suspension, were investigated. The data suggest that although the amine is cleared rapidly by all types of ECs, the mode of uptake varies according to endothelial source. Confluent cultur... | ['Animals', 'Biological Transport', 'Capillaries', 'Cattle', 'Cells, Cultured', 'Cricetinae', 'Cytoskeleton', 'Dose-Response Relationship, Drug', 'Endothelium', 'Epoprostenol', 'Kinetics', 'Rats', 'Serotonin', 'Thromboxane A2', 'Thromboxanes'] | 3,891,416 | [['B01.050'], ['G03.143'], ['A07.015.461.165'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['A11.284.430.214.190.750'], ['G07.690.773.875', 'G07.690.936.500'], ['A10.272.491'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['G01.374.661', 'G02.11... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adenosine 3',5'-monophosphate-dependent protein kinase activity in soluble thyrotropin receptor complex. | cAMP-dependent protein kinase activity was present in a soluble TSH receptor fraction. The Km of this enzyme was 2.2 X 10(-6) M for casein substrate in the absence or presence of 10(-5) M cAMP. A [3H]cAMP-binding protein was also found in this fraction. The Ka for [3H]cAMP-binding was 0.11 X 10(6) M-1, with a total bin... | ['Animals', 'Cattle', 'Cyclic AMP', 'Enzyme Activation', 'Kinetics', 'Protein Kinases', 'Receptors, Cell Surface', 'Receptors, Cyclic AMP', 'Thyroid Gland', 'Thyrotropin'] | 221,190 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[High altitude acute pulmonary edema (author's transl)]. | HAAPE has been recognised only recently but is of real interest as much from the clinical as well as the dogmatic stand-point owing to the complexity of its physiopathological findings. It is encountered at altitudes higher than 4,000 meters either during a first contact or in natives returning from low altitude zones.... | ['Altitude', 'Altitude Sickness', 'Humans', 'Hypoxia', 'Pulmonary Edema'] | 9,854 | [['G16.500.275.058', 'N06.230.058'], ['C08.618.020'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['C08.381.742']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bronchial challenge testing in occupational epidemiology: is the diluent step really necessary? | BACKGROUND: There is no unanimous agreement on the use of a diluent step to preface methacholine challenge testing. The "pros" for this step are that it allows a better training of the patient; the "cons" are that it requires additional time and effort.OBJECTIVE: We examined if there were any systematic effects when ei... | ['Adult', 'Bronchi', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Methacholine Chloride', 'Occupational Exposure'] | 12,141,715 | [['M01.060.116'], ['A04.411.125'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.877.883.555.500', 'D02.675.276.534.500'], ['N06.850.460.350.600']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ceftazidime versus aminoglycoside and (ureido)penicillin combination in the empirical treatment of serious infection. | Urgent treatment of serious infections with broad spectrum antibiotics usually starts before bacteriological evidence of the infective organism(s) becomes available. In this study 471 patients with a clinical diagnosis of sepsis were treated empirically with ceftazidime (CAZ) monotherapy (249 patients), or with an amin... | ['Adult', 'Aged', 'Aminoglycosides', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Ceftazidime', 'Drug Therapy, Combination', 'Female', 'Humans', 'Male', 'Middle Aged', 'Penicillins', 'Treatment Outcome'] | 1,433,118 | [['M01.060.116'], ['M01.060.116.100'], ['D09.408.051'], ['D27.505.954.122.085'], ['C01.150.252'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.065.589.099.750', 'D02.886.108.750', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A multistaged automatic restoration of noisy microscopy cell images. | Automated cell segmentation for microscopy cell images has recently become an initial step for further image analysis in cell biology. However, microscopy cell images are easily degraded by noise during the readout procedure via optical-electronic imaging systems. Such noise degradations result in low signal-to-noise r... | ['Algorithms', 'Artifacts', 'Artificial Intelligence', 'Cell Tracking', 'Data Interpretation, Statistical', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Microscopy', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Signal-To-Noise Ratio', 'Yeasts'] | 25,291,801 | [['G17.035', 'L01.224.050'], ['E05.047'], ['G17.035.250', 'L01.224.050.375'], ['E01.370.225.500.373', 'E01.370.350.557.500', 'E05.200.500.373', 'E05.242.373'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Estimates of cancer burden in Lazio. | AIMS AND BACKGROUND: Since 1983 a population-based cancer registry has been operating in Lazio which provides incidence and survival data and covers the entire Latina province, amounting to 10% of the regional population. The aim of this paper is to provide estimates of the incidence, mortality and prevalence for seven... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Colorectal Neoplasms', 'Cost of Illness', 'Female', 'Humans', 'Incidence', 'Italy', 'Lung Neoplasms', 'Male', 'Melanoma', 'Middle Aged', 'Neoplasms', 'Prevalence', 'Prostatic Neoplasms', 'Registries', 'Sex Distribution', 'Skin Neoplasms', 'Stomach Neoplasms', ... | 24,158,065 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Mathematical model of light diffraction on red blood cells]. | Mathematical model diffraction of laser radiation on red blood smear for population erythrocytes with their normal distribution according to sizes is presented. It was shown during normal distribution of erythrocytes according to sizes that the first maximal pattern diffraction case does not correspond to the medium di... | ['Erythrocytes', 'Humans', 'Light', 'Mathematics', 'Models, Theoretical'] | 3,191,174 | [['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['H01.548'], ['E05.599']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Methodological issues related to longitudinal epidemiological assessment of developmental trajectories in children. | This supplement presents some of the methodological issues that arose during the early phases of protocol development for the National Children's Study (NCS), a probability sample of 100,000 children that will be followed prospectively from pregnancy through 21 years of age, and to share some of the challenges and solu... | ['Adolescent', 'Adolescent Development', 'Child', 'Child Behavior Disorders', 'Child Development', 'Child, Preschool', 'Developmental Disabilities', 'Epidemiologic Methods', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Parents'] | 19,098,135 | [['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['M01.060.406'], ['F03.625.141'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['F03.625.421'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['F01.829.263.500.320', 'I01.880.853.150.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Human heart-type fatty-acid-binding protein as a point-of-care test in the early diagnosis of acute myocardial infarction. | BACKGROUND: At very early stages of acute myocardial infarction (AMI), highly sensitive biomarkers are still lacking.AIM: To evaluate the utility of human heart-type fatty acid-binding protein (h-FABP) for early diagnosis of AMI.DESIGN: Prospective diagnostic study.METHODS: Consecutive patients presenting to the emerge... | ['Early Diagnosis', 'Fatty Acid Binding Protein 3', 'Fatty Acid-Binding Proteins', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Point-of-Care Systems', 'Predictive Value of Tests'] | 17,347,171 | [['E01.390'], ['D12.776.157.170.125'], ['D12.776.157.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N04.590.874'], ['E05.318.370.800.650', 'N05.715.360.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Digital anaesthesia: one injection or two? | BACKGROUND: Digital nerve blocks (DNB) are performed frequently in the Emergency Department (ED). The aim of this study was to establish whether single injection subcutaneous digital nerve block (SDNB) is as effective as the traditional (two injection) digital nerve block (TDNB) for digital anaesthesia.METHOD: Single b... | ['Adolescent', 'Adult', 'Anesthesia, Local', 'Emergency Service, Hospital', 'England', 'Finger Injuries', 'Fingers', 'Hospitals, Teaching', 'Humans', 'Infections', 'Nerve Block', 'Patient Satisfaction', 'Prospective Studies', 'Single-Blind Method', 'Stress, Psychological'] | 20,360,491 | [['M01.060.057'], ['M01.060.116'], ['E03.155.086.231'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['Z01.542.363.300'], ['C26.448.429'], ['A01.378.800.667.430'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['E03.155.086.711', 'E04.525... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ag/g-C3N4 catalyst with superior catalytic performance for the degradation of dyes: a borohydride-generated superoxide radical approach. | A straightforward approach is developed for fabrication of a visible-light-driven Ag/g-C3N4 catalyst. Morphological observation shows that the g-C3N4 sheets are decorated with highly dispersed Ag nanoparticles having an average size of 5.6 nm. The photocatalytic activity measurements demonstrate that the photocatalytic... | ['Borohydrides', 'Coloring Agents', 'Nanostructures', 'Nitriles', 'Photochemical Processes', 'Silver', 'Superoxides', 'Water Pollutants, Chemical'] | 26,220,662 | [['D01.132.105.050', 'D02.203.087.050'], ['D27.720.233'], ['J01.637.512'], ['D02.626'], ['G02.740'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['D01.248.497.158.685.750.850', 'D01.339.431.374.850', 'D01.650.550.750.800', 'D02.389.338.732'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The use of bioluminescence to evaluate the influence of chemotherapeutic drugs on ATP-levels of malignant cell lines. | Influence of various cytostatic agents on intracellular ATP concentrations of malignant cell lines was studied. The HL-60 promyelocytic cell line, the SW-480 cell line, derived from an adenocarcinoma of the colon and the SW-620 cell line, derived from a lymphonodal metastasis of the colon carcinoma, were investigated. ... | ['Adenosine Triphosphate', 'Antineoplastic Agents', 'Cell Line', 'Cell Survival', 'Humans', 'Luminescent Measurements', 'Neoplasms'] | 3,734,700 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D27.505.954.248'], ['A11.251.210'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516'], ['C04']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The roles of tissue nitrate reductase activity and myoglobin in securing nitric oxide availability in deeply hypoxic crucian carp. | In mammals, treatment with low doses of nitrite has a cytoprotective effect in ischemia/reperfusion events, as a result of nitric oxide formation and S-nitrosation of proteins. Interestingly, anoxia-tolerant lower vertebrates possess an intrinsic ability to increase intracellular nitrite concentration during anoxia in ... | ['Allopurinol', 'Animals', 'Carps', 'Female', 'Hypoxia', 'Liver', 'Male', 'Metabolome', 'Muscles', 'Myocardium', 'Myoglobin', 'Nitrate Reductases', 'Nitric Oxide', 'Nitrites', 'Organ Specificity'] | 27,742,892 | [['D03.633.100.759.160'], ['B01.050'], ['B01.050.150.900.493.200.244.248'], ['C23.888.852.079'], ['A03.620'], ['G03.500'], ['A02.633', 'A10.690'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['D08.811.682.655.500'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrastructure of the human myocardium after intermittent ischemia compared to cardioplegia. | A lot of reports informed about the detrimental effects of intermittent ischemia nevertheless this method is still used during coronary surgery. We investigated the myocardial protection due to cardioplegic arrest compared to intermittent ischemia in 120 patients undergoing coronary surgery. In all patients we took myo... | ['Biopsy', 'Cardiac Surgical Procedures', 'Heart Arrest, Induced', 'Humans', 'Intraoperative Care', 'Microscopy, Electron', 'Myocardium', 'Ventricular Fibrillation'] | 3,751,725 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E04.100.376', 'E04.928.220'], ['E04.100.376.374', 'E04.928.220.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Noise-induced hearing loss with chronic otitis media (author's transl)]. | Two different otological noxes add up in their effect. In some cases, however, the first one may cause a reduction of the noxious effect of the second one. Opinions are divided as to whether the susceptibility to noise of an ear with chronic otitis media is increased or decreased. From 14,300 audiograms we selected tho... | ['Adult', 'Audiometry', 'Bone Conduction', 'Chronic Disease', 'Deafness', 'Hearing Loss, Noise-Induced', 'Humans', 'Male', 'Middle Aged', 'Otitis Media', 'Recruitment, Neurophysiological', 'Retrospective Studies'] | 129,650 | [['M01.060.116'], ['E01.370.382.375.060'], ['F02.830.816.263.500', 'G07.888.500.500', 'G11.561.790.263.398'], ['C23.550.291.500'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['C09.218.458.341.887.460', 'C10.597.751.418.341.887.460', 'C23.888.592.763.393.341.887.460'], ['B01.050.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Benefits play key role in recruiting nurses. | The nursing shortage has led healthcare organizations to expand their recruiting efforts, notably by developing attractive employee benefit packages. A variety of cash and noncash incentives can be used to attract nurses, from bonuses and educational loans to free parking and child care. Financial managers should caref... | ['Employee Incentive Plans', 'Nursing Staff, Hospital', 'Personnel Management', 'Personnel Selection', 'Salaries and Fringe Benefits', 'United States'] | 10,294,620 | [['N04.452.677.368'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['N04.452.677'], ['N04.452.677.500'], ['N01.824.417.700', 'N04.452.677.800'], ['Z01.107.567.875']] | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Defective phototransductive disk membrane morphogenesis in transgenic mice expressing opsin with a mutated N-terminal domain. | Retinitis pigmentosa is a heterogeneous group of inherited retinal disorders in which the photoreceptor cells degenerate. A line of transgenic mice expresses a mutant opsin gene that encodes three missense mutations near the amino terminus, including P23H, which is the basis for a common form of dominant retinitis pigm... | ['Animals', 'Cryoultramicrotomy', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Morphogenesis', 'Mutagenesis', 'Photoreceptor Cells', 'Retinal Degeneration', 'Rod Opsins', 'Vision, Ocular'] | 9,372,448 | [['B01.050'], ['E01.370.225.500.620.530.160', 'E01.370.225.750.600.530.160', 'E05.200.500.620.530.160', 'E05.200.750.600.530.160'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Speech recognition ability as a function of duration of deafness in multichannel cochlear implant patients. | Surgical implantation of a multichannel cochlear prosthesis has become a widespread treatment for profound hearing loss. The relationship between duration of hearing loss and speech recognition ability was examined in 20 postlinguistically deafened adults using the Nucleus 22-Channel Cochlear Prosthesis. Data analysis ... | ['Adult', 'Age Factors', 'Aged', 'Cochlear Implants', 'Deafness', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prosthesis Design', 'Regression Analysis', 'Speech Discrimination Tests', 'Speech Perception', 'Time Factors'] | 2,308,444 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.6... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antibacterial and dermal toxicological profiles of ethyl acetate extract from Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae). | BACKGROUND: The emergence in recent years of numerous resistant strains of pathogenic bacteria to a range of formerly efficient antibiotics constitutes a serious threat to public health. Crassocephalum bauchiense, a medicinal herb found in the West Region of Cameroon is used to treat gastrointestinal infections as well... | ['Animals', 'Anti-Bacterial Agents', 'Asteraceae', 'Dermatitis', 'Disease Models, Animal', 'Female', 'Gentamicins', 'Lipids', 'Male', 'Mice', 'Phytotherapy', 'Plant Extracts', 'Plant Leaves', 'Rats', 'Rats, Wistar', 'Skin', 'Staphylococcal Skin Infections', 'Staphylococcus aureus', 'Transaminases'] | 21,615,960 | [['B01.050'], ['D27.505.954.122.085'], ['B01.650.940.800.575.912.250.100'], ['C17.800.174'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D09.408.051.374'], ['D10'], ['B01.050.150.900.649.313.992.635.505.500'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['B01.050.150.900.649.313.992.635.505.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Flavin-containing monooxygenase isoform 2: developmental expression in fetal and neonatal rabbit lung. | Mammalian flavin-containing monooxygenase functions in the oxygenation of numerous xenobiotics containing a soft nucleophile, usually a nitrogen or sulfur. A total of five distinct flavin monooxygenase (FMO) isoforms are expressed in mammals. Individual isoforms are expressed in a sex-, age-, and tissue-specific fashio... | ['Animals', 'Animals, Newborn', 'Aryl Hydrocarbon Hydroxylases', 'Catalysis', 'Cytochrome P-450 Enzyme System', 'Female', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Isoenzymes', 'Lung', 'Oxygenases', 'Pregnancy', 'RNA, Messenger', 'Rabbits', 'Steroid Hydroxylases'] | 10,098,904 | [['B01.050'], ['B01.050.050.282'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G02.130'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G05.308.310'], ['G05.308.320'], ['D08.811.348', 'D12.776.800.300'], ['A04.411'], ['D08.811.682.690'], ['G08.686.784.769'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Paradoxical Increase in Mortality and Rupture of Intracranial Aneurysms in Microsomal Prostaglandin E2 Synthase Type 1-Deficient Mice: Attenuation by Aspirin. | BACKGROUND: Inflammation plays an important role in formation and rupture of intracranial aneurysms. Expression of microsomal prostaglandin E2 (PGE2) synthase type 1 (mPGES-1) is increased in the wall of intracranial aneurysms in humans. PGE2, a by-product of mPGES-1, is associated with inflammation and cerebrovascular... | ['Aneurysm, Ruptured', 'Animals', 'Aspirin', 'Humans', 'Intracranial Aneurysm', 'Intramolecular Oxidoreductases', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Microsomes', 'Mortality', 'Prostaglandin-E Synthases'] | 26,134,597 | [['C14.907.055.185'], ['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['D08.811.399.475'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.9... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of BMI, waist circumference, and waist-to-height ratio for identification of subclinical cardiovascular risk in pediatric kidney transplant recipients. | BACKGROUND: Kidney transplant recipients are at high risk for CV morbidity. However, the measure of obesity that best predicts CV risk has not been established.OBJECTIVE: A prospective, controlled study was conducted to compare the ability of BMI, WC, and WHr to identify CV risk in pediatric kidney transplant recipient... | ['Adolescent', 'Body Mass Index', 'Cardiovascular Diseases', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Male', 'Multivariate Analysis', 'Obesity', 'Prospective Studies', 'ROC Curve', 'Risk Factors', 'Transplant Recipients', 'Waist Circumference', 'Waist-Height... | 30,294,896 | [['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pulsating nasopharyngeal tumor. Case report of spheno-pharyngeal cephalocele]. | We describe a patient with a pulsatile nasopharyngeal tumour. The diagnostic methods such as endoscopy, computed tomography and NMR are illustrated as well as the anatomical details of encephaloceles. Correct diagnosis prevents complications which can occur as a result of mistaking this lesion for a cyst or adenoids. | ['Diagnosis, Differential', 'Encephalocele', 'Endoscopy', 'Female', 'Humans', 'Magnetic Resonance Spectroscopy', 'Middle Aged', 'Paranasal Sinus Diseases', 'Pharyngeal Neoplasms', 'Sphenoid Sinus', 'Tomography, X-Ray Computed'] | 3,744,917 | [['E01.171'], ['C10.500.680.488', 'C16.131.666.680.488', 'C23.300.707.186'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['M01.060.116.630'], ['C08.460.692', 'C09.603.692'], ['C04.588.443.665.710', 'C07.550.745', 'C09.647.710', 'C09.775.549'], ['A04.531.621.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Laparoscopic treatment of large intestinal injuries during colonoscopy]. | Iatrogenic colonic perforation is a rare, but a serious complication of colonoscopy. Incidence varies in between 0.03-3%. Symptoms of injury are strong abdominal pain in relation to colonoscopic examination and pneumoperitoneum on radiologic findings. Laparoscopic approach allows accurate diagnosis and definitive surgi... | ['Colon', 'Colonoscopy', 'Humans', 'Intestinal Perforation', 'Laparoscopy', 'Male', 'Middle Aged'] | 21,634,097 | [['A03.556.124.526.356', 'A03.556.249.249.356'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of opioid peptides on learning and memory processes in the chick. | Several experiments were conducted to examine the effects of intracranial injection of opioid peptides and antagonists on learning and memory in the chick. Pretraining injection of [leu5]enkephalin and the selective delta receptor agonist [D-Pen2,L-Pen5]enkephalin (DPLPE) into the intermediate medial hyperstriatum vent... | ['Animals', 'Attention', 'Brain Mapping', 'Chickens', 'Discrimination Learning', 'Dominance, Cerebral', 'Dose-Response Relationship, Drug', 'Endorphins', 'Enkephalin, D-Penicillamine (2,5)-', 'Enkephalin, Leucine', 'Enkephalins', 'Male', 'Memory', 'Mental Recall', 'Naloxone', 'Receptors, Opioid', 'Receptors, Opioid, de... | 2,539,840 | [['B01.050'], ['F02.830.104.214'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['F02.463.425.280'], ['F02.830.297', 'G11.561.225'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], [... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Perfluoroalkyl substances exposure in early pregnancy and preterm birth in singleton pregnancies: a prospective cohort study. | BACKGROUND: Preterm birth (PTB, < 37 completed weeks' gestation) is one of the global public health concerns. Epidemiologic evidence on the potential impact of perfluoroalkyl substances (PFAS) on PTB is still limited and inconsistent. We aimed to investigate the associations between prenatal PFAS exposure and PTB among... | ['Adult', 'China', 'Cities', 'Environmental Pollutants', 'Female', 'Fluorocarbons', 'Humans', 'Incidence', 'Infant, Newborn', 'Male', 'Maternal Exposure', 'Pregnancy', 'Premature Birth', 'Young Adult'] | 32,493,312 | [['M01.060.116'], ['Z01.252.474.164'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['D27.888.284'], ['D02.455.526.510.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703.520'], ['N06.85... | ['Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Expensive therapies in children: benefit versus cost of combined treatment of recombinant human growth hormone and gonadotropin-releasing hormone analogue in girls with poor height potential. | OBJECTIVE: The combination therapy of gonadotropin-releasing hormone analogues (GnRHa) and recombinant human growth hormone (rhGH) has been used to increase growth in children with premature sexual maturation and attenuated growth. The aim of this report was to study the benefit over cost of combined treatment in girls... | ['Adolescent', 'Body Height', 'Child', 'Drug Costs', 'Drug Therapy, Combination', 'Female', 'Gonadotropin-Releasing Hormone', 'Growth Disorders', 'Growth Hormone', 'Humans'] | 24,158,419 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['M01.060.406'], ['N03.219.151.400.350', 'N05.300.375.300'], ['E02.319.310'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Optimising mobility through the sit-to-stand activity for older people living in residential care facilities: A qualitative interview study of healthcare aide experiences. | AIMS AND OBJECTIVES: To explore the experience of HCAs encouraging residents living in residential care to complete the sit-to-stand activity and to identify the strategies HCAs used to integrate the activity into their daily work routines.BACKGROUND: Decreased mobility in advanced ageing is further reduced when enteri... | ['Activities of Daily Living', 'Aged', 'Female', 'Geriatric Assessment', 'Homes for the Aged', 'Humans', 'Interviews as Topic', 'Male', 'Mobility Limitation', 'Motivation', 'Nursing Assessment', 'Nursing Staff', 'Posture', 'Qualitative Research', 'Time Management'] | 28,971,588 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Pheno... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Serum immunoglobulin A concentration is a reliable biomarker for liver fibrosis in non-alcoholic fatty liver disease. | AIM: To evaluate the diagnostic accuracy of serum Immunoglobulin A (IgA) for differentiating early stage nonalcoholic fatty liver disease (NAFLD) from nonalcoholic steatohepatitis (NASH).METHODS: All cases had fatty liver change confirmed by ultrasound and aminotransferases of at least twice the normal level. Clinical ... | ['Adult', 'Area Under Curve', 'Biomarkers', 'Biopsy', 'Case-Control Studies', 'Disease Progression', 'Female', 'Humans', 'Immunoglobulin A', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Predictive Value of Tests', 'Prognosis', 'ROC Curve', 'Reproducibility of Results', 'Serologic Test... | 25,253,959 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Noise exposure of the ear during surgery (author's transl)]. | We measured the noise generated by three vacuum pipes with different inner diameters in the external ear canal with a probe microphone. The highest level was generated by the largest pipe when solid material blocked part of the entrance. Then we measured peak levels up to 140 dB-C. Such levels generate only low Leq but... | ['Ear, External', 'Hearing Loss, Noise-Induced', 'Humans', 'Noise', 'Postoperative Complications'] | 7,107,339 | [['A09.246.272'], ['C09.218.458.341.887.460', 'C10.597.751.418.341.887.460', 'C23.888.592.763.393.341.887.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['C23.550.767']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Postoperative cardiac insufficiency. The value of enoximone]. | The authors discuss the physiopathological mechanisms of intra and postoperative cardiac failure and the different means of treatment. A distinction is made between the intra and postoperative periods: the factors which predispose to cardiac failure are different and the immediate postoperative period would seem to be ... | ['Acute Disease', 'Anesthesia, General', 'Cardiotonic Agents', 'Enoximone', 'Heart Failure', 'Humans', 'Imidazoles', 'Intraoperative Complications', 'Postoperative Complications', 'Risk Factors'] | 2,147,841 | [['C23.550.291.125'], ['E03.155.197'], ['D27.505.954.411.222', 'D27.720.799.080'], ['D03.383.129.308.253'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['C23.550.505'], ['C23.550.767'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Absorption and release of biogenic amines by the lung during the restorative period after hypovolemic hypotension]. | The processes of serotonin and histamine absorption and release by the lungs were studied in dogs during 1 to 3.5 hour hypovolemic hypotension and during 24 hours after blood retains fusion. Absorption of biogenic amines by the lungs tended to increase in all the animals under hypovolemic hypotension. In the group of n... | ['Animals', 'Blood Volume', 'Cardiac Output', 'Dogs', 'Female', 'Hemodynamics', 'Histamine', 'Hypotension', 'Lung', 'Male', 'Serotonin', 'Time Factors', 'Vascular Resistance'] | 2,337,643 | [['B01.050'], ['G09.188.130', 'G09.330.380.092'], ['E01.370.370.380.150', 'G09.330.380.124'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.380'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['C14.907.514'], ['A04.411'], ['D02.092.211.215.801.852', 'D03.633.100.473.914... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver. | Dichloroacetate (DCA) has potential for treating mitochondrial disorders and cancer by activating the mitochondrial pyruvate dehydrogenase complex. Repeated dosing of DCA results in reduced drug clearance due to inactivation of glutathione transferase æ1 (GSTZ1), its metabolizing enzyme. We investigated the time-course... | ['Animals', 'Cytosol', 'Dichloroacetic Acid', 'Female', 'Glutathione Transferase', 'Liver', 'Mitochondria', 'Rats', 'Rats, Sprague-Dawley'] | 31,524,376 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D02.241.081.018.214.500', 'D02.455.526.439.196.500'], ['D08.811.913.225.500'], ['A03.620'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.75... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. | Mitochondria play essential roles in cellular energy production via the oxidative phosphorylation system (OXPHOS) consisting of five multiprotein complexes and also in the initiation of apoptosis. NADH:ubiquinone oxidoreductase (complex I) is the largest complex that catalyzes the first step of electron transfer in the... | ['Animals', 'Apoptosis', 'Blastocyst', 'Cell Division', 'Electron Transport Complex I', 'Mice', 'Mice, Knockout', 'Microscopy, Confocal', 'Mitochondria', 'NADH, NADPH Oxidoreductases', 'Sequence Deletion'] | 15,367,666 | [['B01.050'], ['G04.146.954.035'], ['A16.254.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D05.500.562.249', 'D08.811.600.250.500.500', 'D08.811.682.608.504', 'D12.776.157.427.374.375.863', 'D12.776.157.530.450.250.875.300', 'D12.776.331.199.500', 'D12.776.543.277.500.500', 'D12.776... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comprehensive fluence model for absolute portal dose image prediction. | Amorphous silicon (a-Si) electronic portal imaging devices (EPIDs) continue to be investigated as treatment verification tools, with a particular focus on intensity modulated radiation therapy (IMRT). This verification could be accomplished through a comparison of measured portal images to predicted portal dose images.... | ['Algorithms', 'Calibration', 'Dose-Response Relationship, Radiation', 'Electronics, Medical', 'Equipment Design', 'Humans', 'Models, Statistical', 'Monte Carlo Method', 'Normal Distribution', 'Particle Accelerators', 'Radiometry', 'Radiotherapy, Intensity-Modulated', 'Reproducibility of Results', 'Sensitivity and Spec... | 19,472,646 | [['G17.035', 'L01.224.050'], ['E05.978.155'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['H01.671.293.319'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH. | ErbB receptors play an important role in normal cellular growth, differentiation and development, but overexpression or poor downregulation can result in enhanced signaling and cancerous growth. ErbB signaling is terminated by clathrin-dependent receptor-mediated endocytosis, followed by incorporation in multi-vesicula... | ['Animals', 'Down-Regulation', 'Endocytosis', 'Endosomal Sorting Complexes Required for Transport', 'Endosomes', 'Epidermal Growth Factor', 'ErbB Receptors', 'HEK293 Cells', 'Humans', 'Mice', 'NIH 3T3 Cells', 'Phosphoproteins', 'Phosphorylation', 'Receptor, ErbB-2', 'Recombinant Fusion Proteins', 'Signal Transduction',... | 22,800,866 | [['B01.050'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G04.417'], ['D05.500.199', 'D12.776.543.990.493'], ['A11.284.430.214.190.875.190.880.337'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glan Clwyd operating space is transformed. | Turnkey construction company, MTX Contracts, has recently completed a suite of five 'modern and future-proofed' operating theatres at the Ysbyty Glan Clwyd in Bodelwyddan, Denbighshire, in the first phase of a 90-phase, 89.9 million pounds sterling redevelopment of facilities at the North Wales hospital being undertake... | ['Efficiency, Organizational', 'Interior Design and Furnishings', 'Operating Rooms', 'United Kingdom'] | 22,984,742 | [['N04.452.209.500'], ['J01.086.339.290'], ['N02.278.388.700'], ['Z01.542.363']] | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Functional, structural, and antigenic similarities of guinea pig anti-phosphorylcholine antibodies. | The humoral immune response to PC was measured in guinea pigs. PC-vaccine stimulated IgM and IgG2, but little IgG1, anti-PC -antibodies. No memory was induced and immunization in CFA produced tolerance. PC-KLH, on the other hand, stimulated IgM, IgG2, and IgG1 anti-PC antibodies with carrier-specific memory. Hapten inh... | ['Animals', 'Antibodies', 'Antibody Formation', 'Antibody Specificity', 'Choline', 'Genotype', 'Guinea Pigs', 'Hemocyanins', 'Hemolytic Plaque Technique', 'Immune Sera', 'Immunoglobulin G', 'Immunoglobulin M', 'Isoelectric Focusing', 'Male', 'Phosphorylcholine', 'Vaccines'] | 325,132 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.450.050.370.250'], ['G12.100'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['G05.380'], ['B01.050.150.900.649.313.992.550'], ['D12.776.093.375', 'D12.776.556.462', 'D23.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feeding behaviors and other motor development in healthy children (2-24 months). | OBJECTIVES: To monitor infant's gross, fine and oral motor development patterns related to feeding.DESIGN: An incomplete block design was used with 57 to 60 (sample = 98) mothers interviewed when their children were 2, 3, 4, 6, 8, 10, 12, 16 and 24 months (within +/- 5 days of birth date). Each mother had 5 to 6 interv... | ['Aging', 'Child Development', 'Drinking', 'Eating', 'Feeding Behavior', 'Humans', 'Infant', 'Motor Skills', 'Mouth', 'Socioeconomic Factors', 'Walking'] | 11,999,548 | [['G07.345.124'], ['F01.525.200', 'G07.345.374.750'], ['G07.203.650.283.249', 'G10.261.330.249'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F02.808.260'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], [... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Norepinephrine increases blood pressure but not survival with anthrax lethal toxin in rats. | OBJECTIVES: The response of anthrax lethal toxin (LeTx) induced shock and lethality to conventional therapies has received little study. Previously, fluids worsened outcome in LeTx-challenged rats in contrast to its benefit with lipopolysaccharide (LPS) or Escherichia coli. The current study investigated norepinephrine... | ['Animals', 'Anthrax', 'Antigens, Bacterial', 'Bacterial Toxins', 'Blood Pressure', 'Norepinephrine', 'Rats', 'Rats, Sprague-Dawley', 'Shock, Septic', 'Survival Rate', 'Vasoconstrictor Agents'] | 19,242,337 | [['B01.050'], ['C01.150.252.410.090.072'], ['D23.050.161'], ['D23.946.123'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The fate of internalized á5 integrin is regulated by matrix-capable fibronectin. | BACKGROUND: Assembly of fibronectin matrices is associated with integrin receptor turnover and is an important determinant of tissue remodeling. Although it is well established that fibronectin is the primary ligand for á5â1 receptor, the relationship between fibronectin matrix assembly and the fate of internalized á5 ... | ['Amino Acid Sequence', 'Animals', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Cytoplasm', 'Fibronectins', 'Humans', 'Integrin alpha5', 'Mice', 'Molecular Sequence Data', 'Proteasome Endopeptidase Complex', 'Ubiquitination'] | 25,062,814 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['A11.284.430.214'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['B01.050.150.900... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A new method of spatial compounding imaging. | A new method of spatial compound imaging is presented that improves image quality without the usual requirement to decrease the frame rate. The new method of imaging utilizes three transducers for data acquisition. The transducer located at the center of the transducer system is a phased array probe that acts as both t... | ['Computer Simulation', 'Humans', 'Image Enhancement', 'Signal Processing, Computer-Assisted', 'Transducers', 'Ultrasonography'] | 12,788,220 | [['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['L01.224.800'], ['E07.305.812'], ['E01.370.350.850']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Unexpected redwood mortality from synergies between wildfire and an emerging infectious disease. | An under-examined component of global change is the alteration of disturbance regimes due to warming climates, continued species invasions, and accelerated land-use change. These drivers of global change are themselves novel ecosystem disturbances that may interact with historically occurring disturbances in complex wa... | ['California', 'Fires', 'Geologic Sediments', 'Phytophthora', 'Plant Diseases'] | 24,358,700 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N06.230.216'], ['G01.311.330', 'G16.500.320'], ['B01.750.580.715'], ['G15.610']] | ['Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Optimization and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human oral fluid. | An analytical procedure was developed and validated for the simultaneous identification and quantification of nicotine, cotinine, trans-3'-hydroxycotinine, and norcotinine in 0.5 mL of human oral fluid collected with the Quantisal oral fluid collection device. Solid phase extraction and liquid chromatography-tandem mas... | ['Chromatography, Liquid', 'Cotinine', 'Gingival Crevicular Fluid', 'Humans', 'Mass Spectrometry', 'Nicotine', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 19,838,828 | [['E05.196.181.400'], ['D03.383.773.812.180'], ['A12.383.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D03.132.760.570', 'D03.383.725.518'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Late clinical outcome in a randomized prospective comparison of colonic J pouch and straight coloanal anastomosis. | BACKGROUND: Functional outcome after rectal excision with coloanal anastomosis is improved by construction of a colonic J pouch. Present prospective randomized studies lack follow-up beyond 1 year. The aim of this study was to assess the clinical outcome at both short- and long-term follow-up.METHODS: Forty patients wi... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anastomosis, Surgical', 'Female', 'Humans', 'Male', 'Middle Aged', 'Proctocolectomy, Restorative', 'Prospective Studies', 'Rectal Neoplasms', 'Treatment Outcome'] | 9,361,611 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.210.219.620', 'E04.210.895.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C04.588.274.476.411.307.790', 'C06.301.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The development of verbal and visual working memory processes: a latent variable approach. | Working memory (WM) processing in children has been studied with different approaches, focusing on either the organizational structure of WM processing during development (factor analytic) or the influence of different task conditions on WM processing (experimental). The current study combined both approaches, aiming t... | ['Adolescent', 'Age Factors', 'Child', 'Child Development', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Recall', 'Photic Stimulation', 'Regression Analysis', 'Speech', 'Verbal Behavior', 'Visual Perception'] | 22,093,922 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.425.540.641'], ['E05.723.729'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['F01... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The role of the premacular liquefied pocket and premacular vitreous cortex in idiopathic macular hole development. | PURPOSE: To clarify the role of the vitreous in idiopathic macular hole formation.METHODS: We prospectively evaluated the vitreous before and during vitreous surgery in 64 consecutive eyes of 62 patients (stage 1B, four eyes; stage 2, ten eyes; stage 3, 43 eyes; stage 4, four eyes) with macular holes; another three eye... | ['Eye Diseases', 'Female', 'Fluorescein Angiography', 'Humans', 'Male', 'Prospective Studies', 'Retinal Perforations', 'Vitrectomy', 'Vitreous Body'] | 8,909,201 | [['C11'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C11.768.740'], ['E04.540.960'], ['A09.371.714.500']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Role of miRNA-1 in regulating connexin 43 in ischemia-reperfusion heart injury: a rat model. | MiRNA-1 may participate in regulating ischemia-reperfusion injury (IRI) by affecting the expression and distribution of connexin 43 (Cx43). The aim of this study is to investigate miR-1 expression and its potential role in regulating Cx43 during ischemic postconditioning (IPOST) in a rat model. Fifty-five Wistar male r... | ['Animals', 'Blotting, Western', 'Connexin 43', 'Disease Models, Animal', 'Gene Expression Regulation', 'Immunohistochemistry', 'Ischemic Postconditioning', 'Isolated Heart Preparation', 'Male', 'MicroRNAs', 'Myocardial Reperfusion Injury', 'Rats', 'Rats, Wistar', 'Real-Time Polymerase Chain Reaction'] | 28,081,514 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.543.585.250.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.308'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
High fertilization success in a surface-brooding Caribbean gorgonian. | Colonies of the Caribbean gorgonian Pseudopterogorgia elisabethae release eggs that are retained on the colony surface where they are fertilized and then develop. In December 2001, spawning on San Salvador Island, Bahamas, occurred over 6 d, with spawning by any one colony limited to 1-3 d. With the exception of the fi... | ['Animals', 'Anthozoa', 'Bahamas', 'Female', 'Fertilization', 'Male'] | 16,501,060 | [['B01.050'], ['B01.050.500.308.237'], ['Z01.107.084.900.100', 'Z01.639.880.100'], ['G08.686.784.277']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Macropodumines A-C: novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq. | Three novel alkaloids, macropodumines A-C (1-3), were isolated from the stem of Daphniphyllum macropodum Miq. Interestingly, the structure of macropodumine A (1) was characterized as having a fused pentacyclic system including an unusual eleven-membered macrolactone ring, whereas macropodumine B (2) contains a rare cyc... | ['Alkaloids', 'Crystallography, X-Ray', 'Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Plants', 'Polycyclic Compounds', 'Spectrometry, Mass, Electrospray Ionization', 'Spectrophotometry, Infrared', 'Spectrophotometry, Ultraviolet'] | 16,642,529 | [['D03.132'], ['E05.196.309.742.225'], ['E05.196.867.519'], ['G02.111.570.820'], ['B01.650'], ['D04'], ['E05.196.566.600'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is a science of psychotherapy possible? Subjectivity problems. | Two sorts of subjectivity problems are discussed. The 1st concerns the characterization of psychotherapy as an attempt to alter clients' meanings. The 2nd concerns the seemingly subjective nature of value judgments about psychotherapy outcomes. It is argued that despite initial appearances, neither of these problems po... | ['Humans', 'Motivation', 'Outcome and Process Assessment, Health Care', 'Psychotherapy', 'Science'] | 11,080,833 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['N04.761.559', 'N05.715.360.575'], ['F04.754'], ['H01.770']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitrosamine 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanone: the impact of a high-fat diet. | Aberrant or excessive expression of cyclooxygenase (COX)-2 has been implicated in the pathogenesis of many disease processes, including carcinogenesis. COX-2 expression was immunohistochemically examined in archival samples (D. Hoffmann et al., Cancer Res., 53: 2758-2761, 1993) of lung neoplasms (adenomas, adenocarcino... | ['Animals', 'Aspirin', 'Carcinogens', 'Cyclooxygenase 2', 'Dietary Fats', 'Immunohistochemistry', 'Isoenzymes', 'Lung Neoplasms', 'Male', 'Nitrosamines', 'Prostaglandin-Endoperoxide Synthases', 'Rats', 'Rats, Inbred F344'] | 10,197,601 | [['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['D27.888.569.100'], ['D08.811.600.720.750'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Targeted reduction of complex models with time scale hierarchy--a case study. | With the increasing flow of biological data there is a growing demand for mathematical tools whereby essential aspects of complex causal dynamic models can be captured and detected by simpler mathematical models without sacrificing too much of the realism provided by the original ones. Given the presence of a time scal... | ['Animals', 'Melanins', 'Melanocyte-Stimulating Hormones', 'Models, Biological', 'Models, Chemical', 'Numerical Analysis, Computer-Assisted'] | 12,941,533 | [['B01.050'], ['D12.125.072.050.875.379', 'D23.767.620'], ['D06.472.699.327.935.531.750', 'D06.472.699.631.525.600.531.750', 'D12.644.400.400.935.531.750', 'D12.644.400.460', 'D12.644.548.365.935.531.750', 'D12.644.548.691.525.690.531.750', 'D12.776.631.650.405.935.531.750', 'D12.776.631.650.460'], ['E05.599.395'], ['E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Serum screening for oncogene proteins in workers exposed to PCBs. | A cohort of 16 municipal workers engaged in cleaning oil from old transformers was examined for possible health effects from exposure to polychlorinated biphenyls (PCBs). In addition to the evaluation of routine clinical parameters (history, physical examination, liver function tests, serum triglycerides, serum PCB val... | ['Adult', 'Environmental Exposure', 'Humans', 'Immunoblotting', 'Male', 'Middle Aged', 'Oncogene Proteins v-sis', 'Oncogenes', 'Polychlorinated Biphenyls', 'Retroviridae Proteins', 'Risk Factors', 'Smoking'] | 3,143,397 | [['M01.060.116'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['M01.060.116.630'], ['D12.776.624.664.520.750.935', 'D12.776.964.700.750.935', 'D12.776.964.775.750.935'], ['G05.360.340.024.340.375.500'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
N-nitro-L-arginine methyl ester blocks the decompensatory phase of acute hypovolaemia in conscious rabbits by a brainstem mechanism. | Graded caval occlusion in conscious rabbits caused a biphasic response. Phase I was characterized by a fall in conductance so that arterial pressure was maintained. When cardiac output had fallen to 71 +/- 4% of its baseline level, phase II supervened. During phase II, conductance rose abruptly and arterial pressure fe... | ['Analysis of Variance', 'Animals', 'Arginine', 'Blood Pressure', 'Blood Volume', 'Brain Stem', 'Cardiac Output', 'Catheterization, Central Venous', 'Catheterization, Peripheral', 'Heart Conduction System', 'Heart Rate', 'In Vitro Techniques', 'Injections, Intravenous', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', ... | 7,493,618 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.188.130', 'G09.330.380.092'], ['A08.186.211.132'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E02.148.167', 'E04.100.814.529.87... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lack of association of heart rate variability parameters with head-up tilt-test responses in patients with syncope. | BACKGROUND: Neurocardiogenic syncope is the most common type of syncope. Head-up tilt testing is the investigation of choice for diagnosis of patients with neurocardiogenic syncope. In this study, we aimed to findout any association between heart rate variability parameters and type of tilt-test response in patients wi... | ['Adult', 'Electrocardiography, Ambulatory', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Posture', 'Syncope, Vasovagal', 'Tilt-Table Test'] | 15,584,566 | [['M01.060.116'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G11.427.695'], ['C10.177.575.600.800', 'C10.597.606.358.800.600.500', 'C23.888.592.604.359.800.600.500'], ['E01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of continuous traffic noise on percentage of deep sleep, waking, and sleep latency. | When subjected to alternating quiet nights (32 dB) and noise nights (equivalent levels of 47 dB) a group of 14 subjects showed an average increase in the fraction of deep sleep of about 2.5% resulting from the traffic noise. Another group of 12 subjects whose noise nights were at 60 dB had an average of 4.6% increase i... | ['Adaptation, Physiological', 'Adult', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Noise', 'Reaction Time', 'Sleep', 'Wakefulness'] | 6,826,889 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.830.855', 'G11.561.803'], ['F02.830.104... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mouse embryonic stem cells with aberrant transforming growth factor beta signalling exhibit impaired differentiation in vitro and in vivo. | Embryonic stem (ES) cells are resistant to transforming growth factor beta (TGF beta). We have shown previously that they lack type-II binding receptors (T beta RII) and in this respect resemble the inner cell mass and ectoderm cells of mouse embryos 4.5-7.5 days post coitum (dpc); they do however express type-I (alk-5... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Chimera', 'Cyclin D', 'Cyclins', 'Embryo, Mammalian', 'Mice', 'Protein-Serine-Threonine Kinases', 'Receptor, Transforming Growth Factor-beta Type II', 'Receptors, Transforming Growth Factor beta', 'Signal Transduction', 'Stem Cells', 'Transfection', 'Transforming ... | 9,697,304 | [['B01.050'], ['G04.152'], ['A11.251'], ['B05.200'], ['D12.644.360.262.150', 'D12.776.167.218.150', 'D12.776.476.262.150'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['A16.254'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.913.696.620.682.700'], ['D08.811.913.696.620.682.700.795', 'D12.776.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prognostic importance of a positive test of myocardial 99mTc-Sn-pyrophosphate accumulation in patients with stable stenocardia]. | The paper reports the results of a retrospective study of the frequency of complications of chronic coronary disease in 51 patients with stable angina subjected to myocardial 99mTc-Sn-pyrophosphate scintigraphy at rest at first screening. In the group with positive scintigraphic results, myocardial infarction and death... | ['Adult', 'Aged', 'Angina Pectoris', 'Chronic Disease', 'Electrocardiography', 'Heart', 'Humans', 'Male', 'Middle Aged', 'Myocardium', 'Polyphosphates', 'Prognosis', 'Radionuclide Imaging', 'Retrospective Studies', 'Technetium', 'Technetium Tc 99m Pyrophosphate', 'Tin Polyphosphates'] | 6,876,546 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['C23.550.291.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D01.029.260.7... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The rhizobacterium Arthrobacter agilis produces dimethylhexadecylamine, a compound that inhibits growth of phytopathogenic fungi in vitro. | Plant diseases caused by fungal pathogens such as Botrytis cinerea and the oomycete Phytophthora cinnamomi affect agricultural production worldwide. Control of these pests can be done by the use of fungicides such as captan, which may have deleterious effects on human health. This study demonstrates that the rhizobacte... | ['Amines', 'Antifungal Agents', 'Arthrobacter', 'Botrytis', 'Culture Media', 'Fragaria', 'Fungi', 'Humans', 'Hydrocarbons', 'Methylamines', 'Phospholipids', 'Phytophthora', 'Trichoderma'] | 23,674,267 | [['D02.092'], ['D27.505.954.122.136'], ['B03.510.024.850.050', 'B03.510.460.400.400.049.074'], ['B01.300.381.128'], ['D27.720.470.305', 'E07.206'], ['B01.650.940.800.575.912.250.859.937.500.266'], ['B01.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455'], ['D02.092.668'], ['D10.570.755'], ['B01.750.580.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endocrine and metabolic responses to realimentation in feed-restricted prepubertal gilts: associations among gonadotropins, metabolic hormones, glucose, and uteroovarian development. | Temporal relationships among plasma LH, FSH, metabolic hormones, and glucose concentrations were studied in nutritionally manipulated prepubertal gilts. Twenty-four growth-matched littermate gilts (73.6 +/- 1.2 kg) were fed at maintenance for 7 d (d 1 to 7). From d 8 to 14, littermates were divided between two treatmen... | ['Aging', 'Animals', 'Blood Glucose', 'Diet', 'Eating', 'Endocrine Glands', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropins', 'Insulin', 'Insulin-Like Growth Factor I', 'Luteinizing Hormone', 'Ovary', 'Sexual Maturation', 'Swine', 'Uterus'] | 8,728,006 | [['G07.345.124'], ['B01.050'], ['D09.947.875.359.448.500'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['A06.300'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.322'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D12.644.276.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Avian polymavirus in wild birds: genome analysis of isolates from Falconiformes and Psittaciformes. | Avian polyomavirus (APV) infections have been reported to cause fatal disease in a wide range of psittacine species. Here we demonstrate APV infections in buzzards (Buteo buteo) and in a falcon (Falco tinnunculus) found dead in Germany, and in lovebirds (Agapornis pullaria) with fatal disease, wild-caught in Mo?ambique... | ['Animals', 'Birds', 'Chick Embryo', 'DNA, Viral', 'Genome, Viral', 'Phylogeny', 'Polyomavirus', 'Restriction Mapping', 'Viral Structural Proteins'] | 9,739,329 | [['B01.050'], ['B01.050.150.900.248'], ['A13.350.150', 'A16.331.200'], ['D13.444.308.568'], ['G05.360.340.358.840'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B04.280.210.700.615', 'B04.613.204.670.615'], ['E05.393.183.620.650', 'E05.393.712'], ['D12.776.964.970']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A paradise for parasites? Seven new haemogregarine species infecting lizards from the Canary Islands. | Oceanic islands are hotspots of biodiversity due to their high levels of endemism, with the Canary Islands being a notable example. A previous molecular study on the biogeography and host associations of haemogregarines (Apicomplexa: Adeleorina) infecting lizards from this archipelago detected seven parasite haplogroup... | ['Animals', 'Cluster Analysis', 'Coccidiosis', 'DNA, Protozoan', 'DNA, Ribosomal', 'Eucoccidiida', 'Haplotypes', 'Host Specificity', 'Lizards', 'Phylogeny', 'RNA, Ribosomal, 18S', 'Sequence Analysis, DNA', 'Spain'] | 30,871,644 | [['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['C01.610.752.250'], ['D13.444.308.442'], ['D13.444.308.475'], ['B01.043.075.189.275'], ['G05.380.360'], ['G06.462.380', 'G16.527.200.380'], ['B01.050.150.900.833.393'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.675'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
[The role of ultrasonography in second trimester screening for fetal chromosome aberrations]. | UNLABELLED: The role of ultrasound examination in second trimester screening for fetal aneuploidies.OBJECTIVE: Authors sought to determine the frequency of ultrasound findings in major chromosomal defects. They also tried to evaluate possible patterns of ultrasound signs of fetal chromosomal defects.METHODS: Through th... | ['Adult', 'Aneuploidy', 'Chromosome Aberrations', 'Chromosomes, Human, Pair 13', 'Chromosomes, Human, Pair 18', 'Chromosomes, Human, Pair 21', 'Female', 'Fetal Diseases', 'Humans', 'Mass Screening', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Trimester, Second', 'Trisomy', 'Turner Syndrome', 'Ultrasonography, ... | 17,209,302 | [['M01.060.116'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.370.375', 'G05.360.162.520.300.370.375'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['C13.703.277',... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of physical and cytogenetic estimates of radiation dose in patients treated with iodine-131 for thyroid carcinoma. | Physical and cytogenetic estimates of the whole-body radiation doses have been compared in 11 patients receiving large doses of iodine-131 for the treatment of thyroid carcinoma. The physical estimate was based on the measurement of thyroid uptake, of the plasma activity variation, and of urinary activity. The cytogene... | ['Body Burden', 'Chromosome Aberrations', 'Humans', 'Iodine Radioisotopes', 'Lymphocytes', 'Radiation Dosage', 'Radiotherapy', 'Thyroid Neoplasms'] | 1,087,288 | [['E05.799.638.231', 'N06.850.460.200'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mouse monoclonal antibody (WI-MN-1) against malignant melanoma. | A mouse monoclonal antibody, WI-MN-1, was raised against G-361 melanoma cell line. Reactivity of this antibody was characterized by indirect immunofluorescence against 22 cell lines and normal and neoplastic human tissues. Positive reactions were seen against three melanoma cell lines (G-361, HT-144, and MeWo). It also... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Cell Line', 'Epitopes', 'Fluorescent Antibody Technique', 'Humans', 'Immunoenzyme Techniques', 'Lymphocytes', 'Melanoma', 'Mice', 'Mice, Inbred BALB C'] | 6,196,109 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['A11.251.210'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Further pharmacological studies on aqueous seed extract of Aframomum melegueta in rats. | This present study investigates the effect of an aqueous seed extract of Aframomum melegueta, on leukocytes migration and on phenylhydrazine-treated rat red blood cells (RBC). The effect of Aframomum melegueta on the number of white blood cells (WBC), in inflammatory exudates, was assessed by utilizing the granuloma ai... | ['Animals', 'Anti-Inflammatory Agents', 'Antioxidants', 'Dose-Response Relationship, Drug', 'Erythrocyte Membrane', 'Erythrocytes', 'Female', 'Granuloma', 'Hemolysis', 'Inflammation', 'Leukocytes', 'Male', 'Malondialdehyde', 'Medicine, African Traditional', 'Nigeria', 'Phenylhydrazines', 'Plant Extracts', 'Rats', 'Seed... | 18,060,710 | [['B01.050'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C15.604.515.292', 'C23.550.382'], ['C23.550.403', 'G12.122.545'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 |
The mRNA-bound Proteome of Leishmania mexicana | Leishmania parasite infections, termed the leishmaniases, cause significant global infectious disease burden. The lifecycle of the parasite embodies three main stages that require precise coordination of gene regulation to survive environmental shifts between sandfly and mammalian hosts. Constitutive transcription in k... | ['Animals', 'Gene Ontology', 'Leishmania mexicana', 'Life Cycle Stages', 'Mice, Inbred BALB C', 'Parasites', 'Principal Component Analysis', 'Proteome', 'Proteomics', 'Protozoan Proteins', 'RNA, Messenger', 'RNA-Binding Proteins', 'Reproducibility of Results', 'Transcriptome'] | 30,948,621 | [['B01.050'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['B01.268.475.868.488.410'], ['B05.500', 'G07.345.500.550.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.05... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Brief report: Repetitive behaviours in Greek individuals with autism spectrum disorder. | The main objective of this study was to examine the factor structure of restricted repetitive behaviours (RRBs) in a sample of 205 Greek individuals with Autism Spectrum Disorder (ASD), using the Repetitive Behavior Scale-Revised (RBS-R). Results show that the structure of RRBs in this Greek sample can be described usi... | ['Adolescent', 'Adult', 'Ceremonial Behavior', 'Child', 'Child Development Disorders, Pervasive', 'Child, Preschool', 'Compulsive Behavior', 'Factor Analysis, Statistical', 'Female', 'Greece', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Self-Injurious Behavior', 'Severity of Illness Index', 'S... | 20,108,116 | [['M01.060.057'], ['M01.060.116'], ['F01.145.813.097', 'I01.076.201.450.170'], ['M01.060.406'], ['F03.625.164'], ['M01.060.406.448'], ['F01.145.527.100'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Laurentixanthones A and B, antimicrobial xanthones from Vismia laurentii. | A phytochemical investigation of the constituents of the roots of Vismia laurentii has resulted in the isolation of two xanthone derivatives named laurentixanthone A (1) (6-hydroxy-3,3-dimethyl-11-(3-methylbut-2-enyl)pyrano[2,3-c]xanthen-7(3H)-one) and laurentixanthone B (2) (1-hydroxy-5,6,7,8-tetramethoxyxanthone), al... | ['Anti-Infective Agents', 'Clusiaceae', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Xanthenes', 'Xanthones'] | 16,740,282 | [['D27.505.954.122'], ['B01.650.940.800.575.912.250.859.625'], ['B03.440'], ['B03.510'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D03.633.300.953'], ['D03.633.300.953.852']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonsteroidal anti-inflammatory drug-associated colitis with a histology of collagenous colitis. | Here we report a case of nonsteroidal anti-inflammatory drug (NSAID)-associated colitis with a histology of collagenous colitis in a 77-year-old woman. The patient had taken aspirin since 1993 after being diagnosed at another hospital, as having multiple cerebral infarctions. She began to suffer from intermittent diarr... | ['Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Aspirin', 'Colitis', 'Collagen', 'Colonoscopy', 'Diarrhea', 'Female', 'Humans', 'Pregnancy', 'Recurrence'] | 11,473,337 | [['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389.657.410.595.176'], ['C06.405.205.265', 'C06.405.469.158.188'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of prostaglandins(PGs) on progesterone production by human cultured luteal cells and their ability of PGs production]. | The present study was designed to investigate whether or not prostaglandins(PGs) were produced by human luteal cells(HLC) and their effects on the luteal cells by monolayer culture. The following results were obtained. Cultured HLC secreted progesterone(P), prostaglandin F(PGF) and prostaglandin E(PGE) into a medium at... | ['Adult', 'Cells, Cultured', 'Corpus Luteum', 'Female', 'Humans', 'Indomethacin', 'Luteal Cells', 'Luteal Phase', 'Progesterone', 'Prostaglandins'] | 3,224,725 | [['M01.060.116'], ['A11.251'], ['A05.360.319.114.630.278', 'A06.300.312.497.278'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['A05.360.319.114.630.278.400', 'A06.300.312.497.278.400', 'A11.382.921', 'A11.436.566'], ['G08.686.605.410'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Variable Digestion Strategies for Phosphoproteomics Analysis. | In recent years, mass spectrometry-based phosphoproteomics has propelled our knowledge about the regulation of cellular pathways. Nevertheless, typically applied bottom-up strategies have several limitations. Trypsin, the preferentially used proteolytic enzyme shows impaired cleavage efficiency in the vicinity of phosp... | ['Chromatography, High Pressure Liquid', 'Chromatography, Reverse-Phase', 'Computational Biology', 'Databases, Protein', 'HeLa Cells', 'Humans', 'Peptide Mapping', 'Phosphopeptides', 'Phosphorylation', 'Protein Processing, Post-Translational', 'Proteolysis', 'Proteomics', 'Solid Phase Extraction', 'Subtilisin', 'Tandem... | 26,584,929 | [['E05.196.181.400.300'], ['E05.196.181.400.495'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.11... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities. | The yeast Saccharomyces cerevisiae catalytic DNA polymerase I 180-kDa subunit and the tightly associated 86-kDa polypeptide have been purified using immunoaffinity chromatography, permitting further characterization of the DNA polymerase activity of the DNA primase-DNA polymerase protein complex. The subunits were puri... | ['Animals', 'Chromatography, Affinity', 'DNA Primase', 'DNA-Directed DNA Polymerase', 'Drosophila melanogaster', 'Electrophoresis, Polyacrylamide Gel', 'Gene Expression Regulation, Fungal', 'Hot Temperature', 'Plasmids', 'RNA', 'RNA Nucleotidyltransferases', 'Saccharomyces cerevisiae'] | 1,704,371 | [['B01.050'], ['E05.196.181.400.170'], ['D08.811.913.696.445.735.270.375'], ['D08.811.913.696.445.308.300'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.308.330'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.23... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Temporal dynamics of binocular disparity processing with corticogeniculate interactions. | A neural model is developed to probe how corticogeniculate feedback may contribute to the dynamics of binocular vision. Feedforward and feedback interactions among retinal, lateral geniculate, and cortical simple and complex cells are used to simulate psychophysical and neurobiological data concerning the dynamics of b... | ['Computer Simulation', 'Geniculate Bodies', 'Models, Neurological', 'Vision Disparity', 'Visual Cortex'] | 12,022,507 | [['L01.224.160'], ['A08.186.211.200.317.826.701.444'], ['E05.599.395.642'], ['F02.463.593.778.255.780', 'F02.463.593.932.877', 'G14.930'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953']] | ['Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Alcohol Use and Drinking Motives Among Suddenly Bereaved College Students. | Objective: Thousands of Americans grieve the sudden death of a loved one each year. These sudden deaths may be the result of violent deaths, as in the cases of homicide, suicide, or fatal accidents, or may occur as the result of natural causes such as heart attacks or strokes. Sudden loss survivors often experience neg... | ['Adult', 'Alcohol Drinking in College', 'Bereavement', 'Female', 'Humans', 'Male', 'Motivation', 'Stress, Psychological', 'Students', 'Young Adult'] | 30,451,601 | [['M01.060.116'], ['F01.145.317.269.625'], ['F01.470.142'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['F01.145.126.990', 'F02.830.900'], ['M01.848'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Death within 30 days of fine needle aspiration: Post-mortem confirmation of FNA diagnoses and the contribution of FNA to patient mortality. | BACKGROUND: Fine needle aspiration (FNA) diagnoses are usually confirmed via surgical pathology or via evaluation of clinical outcomes. However, such confirmation may not occur for patients who die shortly after FNA, and autopsy may be a useful quality assessment tool in these cases. Also, there is little data investig... | ['Adult', 'Aged', 'Autopsy', 'Biopsy, Fine-Needle', 'Death', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Retrospective Studies'] | 30,353,701 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['C23.550.26... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.