Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoclonal antibodies against diagnostic Anisakis simplex antigens. | Five monoclonal antibodies (UA2, UA3, UA5, UA6, and UA8) specific for Anisakis simplex are described. All are IgG1/kappa monoclonal antibodies, except for UA2, which is an antibody IgM/kappa. The molecular weights of the major components recognized in immunoblotting are 48 and 67 kDa (UA2); 139 kDa (UA3 and UA5; same e... | ['Animals', 'Anisakis', 'Antibodies, Helminth', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Antigens, Helminth', 'Dogs', 'Epitopes, B-Lymphocyte', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Rabbits'] | 9,342,739 | [['B01.050'], ['B01.050.500.500.294.400.500.100.075'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['D23.050.223'], ['B01.050.150.900.649.313.750.250.216.200'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relation of induced to spontaneous ventricular tachycardia from analysis of stored far-field implantable defibrillator electrograms. | Predischarge testing of implantable cardioverter-defibrillators is often used to tailor antitachycardia pacing algorithms based on the response of induced ventricular tachycardia (VT) to pacing. Despite this practice, little is known about the relation between VT induced at predischarge study and VT that occurs spontan... | ['Algorithms', 'Coronary Disease', 'Defibrillators, Implantable', 'Electrocardiography', 'Electronic Data Processing', 'Follow-Up Studies', 'Heart Rate', 'Humans', 'Male', 'Prognosis', 'Recurrence', 'Tachycardia, Ventricular'] | 10,072,222 | [['G17.035', 'L01.224.050'], ['C14.280.647.250', 'C14.907.585.250'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E01.370.370.380.240', 'E01.370.405.240'], ['L01.224.085'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.875.500', 'G09.330... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Timing of harvest of Phragmites australis (CAV.) Trin. ex Steudel affects subsequent canopy structure and nutritive value of roughage in subtropical highland. | In recent decades, constructed wetlands dominated by common reeds [Phragmites australis (CAV.) Trin. ex Steudel] have been utilized for treating nitrogen-rich wastewaters. Although plant harvest is a vegetation management in constructed wetlands for the purpose of improving nutrient removal, harvested biomass has becom... | ['Animal Feed', 'Animals', 'Biomass', 'China', 'Dietary Fiber', 'Nutritive Value', 'Poaceae', 'Ruminants', 'Seasons', 'Time Factors', 'Wetlands'] | 26,555,098 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.252.474.164'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['B01.650.940.800.575.912.250.822'], ['B01.050.150.900.649.313.500.380'], ['G01... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Rational design and synthesis of a novel class of active site-targeted HIV protease inhibitors containing a hydroxymethylcarbonyl isostere. Use of phenylnorstatine or allophenylnorstatine as a transition-state mimic. | A novel class of HIV-1 protease inhibitors containing a hydroxymethylcarbonyl (HMC) isostere were designed from the substrate transition state and synthesized. Phenylnorstatine [Pns; (2R,3S)-3-amino-2-hydroxy-4-phenylbutyric acid] and the 2S diastereomer, (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid, named allophenyl... | ['Amino Acid Sequence', 'Binding Sites', 'HIV Protease Inhibitors', 'Molecular Sequence Data', 'Phenylbutyrates', 'Protease Inhibitors'] | 1,804,562 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['D27.505.519.389.745.900.500', 'D27.505.954.122.388.077.088.420'], ['L01.453.245.667'], ['D02.241.223.651'], ['D27.505.519.389.745']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sex-specific effects of daily exposure to sucrose on spatial memory performance in male and female rats, and implications for estrous cycle stage. | Excessive consumption of sugar sweetened drinks is proposed to produce functional changes in the hippocampus, leading to perturbations in learning and memory. In this study we examined the impact of 2h daily access to 10% sucrose (or no sucrose in controls) on recognition memory tasks in young male and female rats. In ... | ['Analysis of Variance', 'Animals', 'Body Weight', 'Estrogens', 'Estrous Cycle', 'Exploratory Behavior', 'Female', 'Male', 'Progesterone', 'Rats', 'Rats, Sprague-Dawley', 'Recognition, Psychology', 'Sex Characteristics', 'Spatial Memory', 'Sucrose', 'Sweetening Agents'] | 26,828,038 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D27.505.696.399.472.277'], ['G08.686.195'], ['F01.145.387', 'F01.658.370'], ['D04.210.500.745.745.654.829', 'D06.472.334... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The importance of agricultural tire habitats for mosquitoes of public health importance in New York State. | The presence of mosquito species breeding in agricultural "bunker tires" on dairy farms in New York state was evaluated. Twelve species of mosquitoes (Aedes vexans, Anopheles barberi, An. punctipenriis, An. perplexens, Culex pipiens pipiens, Cx. restuans, Cx. salinarius, Cx. territans, Toxorhynchites rutilus septentrio... | ['Aedes', 'Animals', 'Anopheles', 'Culex', 'Culicidae', 'Dairying', 'Environment', 'Humans', 'Insect Vectors', 'Larva', 'Mosquito Control', 'New York', 'Ochlerotatus', 'Reproduction'] | 16,033,118 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['J01.040.246'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Entitlement to Tell on Police Facebook Sites. | Despite the increased use of social media by the police, little qualitative exploration has been carried out regarding how online spaces such as Facebook might be important sites for Police Force identity. This study qualitatively analyzes a popular story told on the official Facebook site of a rural police force. It a... | ['Community Participation', 'Humans', 'Police', 'Power, Psychological', 'Qualitative Research', 'Social Media', 'Trust'] | 30,896,973 | [['N02.421.143.212', 'N03.540.245.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.373.750', 'M01.526.760'], ['F01.658.780'], ['H01.770.644.241.850'], ['L01.178.751', 'L01.224.230.110.500.750'], ['F01.829.401.825']] | ['Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Antioxidant activities and bioactive compounds of five Jalopeno peppers (Capsicum annuum) cultivars. | The present study was designed to evaluate the contents of different antioxidants compounds and their antioxidant activities in Jalopeno peppers (Capsicum annuum) cultivars (El Dorido, Grande, Tula, Sayula and El Rey) extracts. Free radical scavenging activity of Grande was recorded as high as 87% followed by El Dorido... | ['Antioxidants', 'Ascorbic Acid', 'Capsicum', 'Carotenoids', 'Flavonoids', 'Fruit', 'Phenols', 'Phytochemicals', 'Plant Extracts'] | 29,212,371 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['B01.650.940.800.575.912.250.908.500.145'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Effects of cutting and reseeding on the ground-dwelling arthropod community in Caragana intermedia forest in desert steppe]. | Taking a 25-year-old Caragana intermedia forest in desert steppe as test object, an investigation was conducted on the ground-dwelling arthropod community in cutting and no-cutting stands with and without reseeding, aimed to understand the effects of cutting, reseeding and their interaction on the individual number and... | ['Animals', 'Arthropods', 'Caragana', 'China', 'Desert Climate', 'Ecosystem', 'Poaceae', 'Population Dynamics'] | 23,718,012 | [['B01.050'], ['B01.050.500.131'], ['B01.650.940.800.575.912.250.401.098'], ['Z01.252.474.164'], ['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['G16.500.275.157', 'N06.230.124'], ['B01.650.940.800.575.912.250.822'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Levels of eight heavy metals and health risk assessment considering food consumption by China's residents based on the 5th China total diet study. | The total diet study (TDS) is a significant part of food consumption-based health risk assessment. Since 1990, China has conducted five TDSs based on its unique food culture. In the present study, the health risks of residents from 20 regions of China are assessed by comparing the estimated daily intake (EDI) with adeq... | ['China', 'Diet', 'Dietary Exposure', 'Environmental Pollutants', 'Food Contamination', 'Humans', 'Metals, Heavy', 'Risk Assessment'] | 31,466,154 | [['Z01.252.474.164'], ['G07.203.650.240'], ['N06.850.460.350.040'], ['D27.888.284'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556', 'D01.552.544'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', '... | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Breeding objectives for pigs in Kenya. II: economic values incorporating risks in different smallholder production systems. | This study estimated economic values for production traits (dressing percentage (DP), %; live weight for growers (LWg), kg; live weight for sows (LWs), kg) and functional traits (feed intake for growers (FEEDg), feed intake for sow (FEEDs), preweaning survival rate (PrSR), %; postweaning survival (PoSR), %; sow surviva... | ['Animal Feed', 'Animal Husbandry', 'Animals', 'Body Weight', 'Breeding', 'Costs and Cost Analysis', 'Kenya', 'Models, Economic', 'Survival Rate', 'Swine'] | 25,433,647 | [['G07.203.300.300.100', 'J02.500.300.100'], ['J01.040.090'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.820.150', 'G05.090'], ['N03.219.151'], ['Z01.058.290.120.400'], ['E05.318.740.500.600', 'E05.599.835.890', 'N05.715.360.75... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Computerized ventilator data selection: artifact rejection and data reduction. | OBJECTIVE: To determine acceptable strategies for automated data acquisition and artifact rejection from computerized ventilators using the Medical Information Bus.DESIGN: Medical practitioners were surveyed to establish 'clinically important' ventilator events. A prospective study involving frequent data collection fr... | ['Adult', 'Algorithms', 'Data Collection', 'Electronic Data Processing', 'Humans', 'Point-of-Care Systems', 'Prospective Studies', 'Reproducibility of Results', 'Respiration, Artificial'] | 9,387,006 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['L01.224.085'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N04.590.874'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Atypical androgen receptor in the human melanoma cell line IIB-MEL-J. | To evaluate the presence of androgen receptors in the human melanoma cell line IIB-MEL-J, a Scatchard plot analysis was performed. Cells in culture revealed a single binding component with an apparent dissociation constant (KD) at 37 degrees C of 11 nM and a binding capacity of 326 fmol/mg protein when measured with [3... | ['Androgen Antagonists', 'Animals', 'Antibodies, Monoclonal', 'Antineoplastic Agents, Hormonal', 'Binding, Competitive', 'Cell Division', 'Dihydrotestosterone', 'Estradiol', 'Flutamide', 'Humans', 'Hydrocortisone', 'Immunohistochemistry', 'Male', 'Melanoma', 'Metribolone', 'Mice', 'Mice, Nude', 'Progesterone', 'Recepto... | 7,567,789 | [['D06.347.065', 'D27.505.696.399.450.065'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248.169'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D04.210.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Parents' hostility in dyadic marital and triadic family settings and children's behavior problems. | The authors examined the relation between parents' hostility during conflict-focused discussions and child behavior problems. Parents engaged in 3 discussions: a dyadic marital discussion of marital disagreements, a dyadic marital discussion of child-related disagreements, and a triadic family discussion with the child... | ['Adolescent', 'Child', 'Child Behavior Disorders', 'Conflict, Psychological', 'Female', 'Gender Identity', 'Hostility', 'Humans', 'Internal-External Control', 'Male', 'Marriage', 'Parent-Child Relations', 'Parenting', 'Personality Assessment', 'Risk Factors'] | 11,550,741 | [['M01.060.057'], ['M01.060.406'], ['F03.625.141'], ['F01.658.209'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['F01.470.596'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Barriers to self-management of diabetes: a qualitative study among low-income minority diabetics. | OBJECTIVES: Diabetes self-management is a key element in the overall management of diabetes. Identifying barriers to disease self-management is a critical step in achieving optimal health outcomes. Our goal was to explore patients' perceptions about barriers to self-management of diabetes that could possibly help expla... | ['Adult', 'African Americans', 'Aged', 'Aged, 80 and over', 'Baltimore', 'Continuity of Patient Care', 'Diabetes Mellitus', 'Female', 'Focus Groups', 'Health Knowledge, Attitudes, Practice', 'Health Literacy', 'Humans', 'Male', 'Middle Aged', 'Poverty', 'Self Care'] | 21,462,726 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['C18.452.394.750', 'C19.246'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Bulge ductility of several occlusal contact measuring paper-based and plastic-based sheets. | Articulating paper/film is a sheet strip that is coated with ink- or dye-containing wax and is used for marking occlusal contacts and monitoring the results. New types of occlusal film systems have been developed recently, which are capable of being computer-interfaced to identify the occlusal contact points and digiti... | ['Coloring Agents', 'Dental Occlusion, Balanced', 'Humans', 'Image Processing, Computer-Assisted', 'Ink', 'Materials Testing', 'Occlusal Adjustment', 'Paper', 'Photography', 'Plastics', 'Waxes'] | 9,408,578 | [['D27.720.233'], ['E06.276.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['J01.637.500'], ['E05.570'], ['E06.658.578.200'], ['J01.637.650'], ['E01.370.350.600', 'E05.712'], ['D05.750.716', 'D25.720.716', 'J01.637.051.720.716'], ['D10.945']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Effects of nicotine on blood flow and delayed neuronal death following intermittent transient ischemia in rat hippocampus. | A cholinergic neural vasodilative response in the cerebral cortex and hippocampus, independent of metabolic vasodilation, was recently demonstrated by activating the nicotinic acetylcholine receptors (nAChRs) via activation of cholinergic neurons originating in the nucleus basalis of Meynert and septal complex in the b... | ['Animals', 'Cell Death', 'Hippocampus', 'Injections, Intravenous', 'Ischemic Attack, Transient', 'Male', 'Nicotine', 'Nicotinic Agonists', 'Rats', 'Rats, Wistar', 'Receptors, Nicotinic', 'Regional Blood Flow', 'Vasodilation'] | 11,173,554 | [['B01.050'], ['G04.146'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['D03.132.760.570', 'D03.383.725.518'], ['D27.505.519.625.120.140.700', 'D27.505.696.577.120.140.700'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronicity of rheumatoid arthritis affects the responsiveness of physical function, but not of disease activity measures in rheumatoid arthritis clinical trials. | BACKGROUND: In previous studies it has been indicated that functional measures are less responsive in patients with established or late rheumatoid arthritis (RA) as compared with early RA, potentially because chronic irreversible functional damage is present. Therefore, they may not be useful as disease activity measur... | ['Adalimumab', 'Adult', 'Aged', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Chronic Disease', 'Clinical Trials as Topic', 'Disease Progression', 'Etanercept', 'Female', 'Humans', 'Immunoglobulin G', 'Infliximab', 'Isoxazoles', 'Leflunomide', 'Male', '... | 24,431,396 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.06... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of a strong-binding myosin analogue on calcium-sensitive mechanical properties of skinned skeletal muscle fibers. | The ability of strong-binding myosin heads to activate the thin filament was investigated by incubating skinned single muscle fibers with N-ethylmaleimide-(NEM) modified myosin subfragment-1 (S1). Isometric force was influenced in a complex manner: during maximal calcium activation, NEM-S1 inhibited force with half-max... | ['Animals', 'Calcium', 'Ethylmaleimide', 'Isometric Contraction', 'Microscopy, Fluorescence', 'Muscles', 'Myosins', 'Rabbits'] | 1,400,367 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['G11.427.494.472'], ['E01.370.350.515.458', 'E05.595.458'], ['A02.633', 'A10.690'], ['D05.750.078.730.475', 'D08.811.277.040.025.193.750', 'D12.776.210.500.600', 'D12.776.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolic and cardiovascular responses following oral and nasal intubation of the trachea. | The cardiovascular and metabolic responses to oral and nasal intubation of the trachea were studied in 24 unpremedicated patients, free from cardiovascular disease and scheduled for excision of breast lump. Systolic blood pressure (SBP) and heart rate (HR) were recorded with a Dinamap 1846 SX before and at 1 minute int... | ['Adolescent', 'Adult', 'Blood Pressure', 'Carbon Dioxide', 'Female', 'Heart Rate', 'Humans', 'Intubation, Intratracheal', 'Middle Aged', 'Mouth', 'Nose', 'Oxygen Consumption'] | 2,124,409 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['M01.060.116.630'], ['A01.456.505.631', 'A03.556.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Estrogen- and androgen-sensitive bioassays based on primary cell and tissue slice cultures from three-spined stickleback (Gasterosteus aculeatus). | Endocrine disrupting compounds are chemicals that may interfere with the endocrine system causing severe effects in organisms. The three-spined stickleback (Gasterosteus aculeatus L.) offers a potential for the assessment of endocrine disruption caused by a) estrogenic xenobiotics through the estrogen-dependent protein... | ['Androgens', 'Animals', 'Biological Assay', 'Biomarkers', 'Cells, Cultured', 'Estrogens', 'Female', 'Fish Proteins', 'Hepatocytes', 'Hormone Antagonists', 'Kidney', 'Liver', 'Male', 'Sewage', 'Smegmamorpha', 'Tissue Culture Techniques', 'Vitellogenins', 'Water Pollutants, Chemical'] | 17,627,896 | [['D27.505.696.399.472.161'], ['B01.050'], ['E05.091'], ['D23.101'], ['A11.251'], ['D27.505.696.399.472.277'], ['D12.776.325'], ['A11.436.348'], ['D06.347', 'D27.505.696.399.450'], ['A05.810.453'], ['A03.620'], ['D20.944.932.500'], ['B01.050.150.900.493.850'], ['E05.481.500.617'], ['D12.776.093.500.925', 'D12.776.290.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolated severe microblepharon in a neonate: a rare case. | PURPOSE: To report a rare case of isolated severe microblepharon in a neonate.METHODS: A 27 days old male child was brought by parents with redness, photophobia and discharge for two weeks. Thorough ophthalmological and systemic examination was performed.RESULTS: The diagnosis of isolated severe microblepharon with inf... | ['Blepharoplasty', 'Eyelid Diseases', 'Eyelids', 'Humans', 'Infant, Newborn', 'Male', 'Rare Diseases', 'Skin Transplantation'] | 28,803,395 | [['E04.540.104', 'E04.680.275.090'], ['C11.338'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C23.550.291.906'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cytokines and neutrophils responses in influenza pneumonia. | This case report shows a striking correlation of remarkable brief high levels of pro- and anti-inflammatory cytokines coupled with increased neutrophil activation, followed by a sharp decrease in cytokine levels and increased neutrophil apoptosis associated with the favorable clinical outcomes of a patient with severe ... | ['Cytokines', 'Female', 'Humans', 'Influenza, Human', 'Middle Aged', 'Neutrophils', 'Pneumonia, Viral'] | 23,589,279 | [['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['M01.060.116.630'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['C01.748.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spatial arrangement of cerebro-pontine terminals. | Understanding the interaction of the cerebral cortex and cerebellum requires knowledge of the highly complex spatial characteristics of cerebro-cerebellar signal transfer. Cerebro-pontine fibers from one neocortical site terminate in several sharply demarcated patches across large parts of the pontine nuclei (PN), and ... | ['Animals', 'Brain Mapping', 'Cerebral Cortex', 'Dendrites', 'Female', 'Fluorescent Dyes', 'Male', 'Motor Cortex', 'Neocortex', 'Neural Pathways', 'Pons', 'Presynaptic Terminals', 'Rats', 'Rats, Sprague-Dawley', 'Somatosensory Cortex', 'Stereotaxic Techniques', 'Visual Cortex'] | 11,406,823 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['A08.186.211.200.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ernst Ferdinand Sauerbruch: rise and fall of the pioneer of thoracic surgery. | Ferdinand Sauerbruch (1875-1951) was a pioneer of thoracic and cardiac surgery and is undoubtedly one of the twentieth century's most outstanding surgeons. Before 1904 operations on the thorax met with fatal complications due to pneumothorax. Sauerbruch developed a pressure-differential chamber that maintained normal r... | ['Equipment Design', 'Germany', 'History, 20th Century', 'Thoracic Surgery'] | 11,571,966 | [['E05.320'], ['Z01.542.315'], ['K01.400.504.968'], ['H02.403.810.803']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Humanities [K]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Tired blood and rusty livers. | Iron deficiency is one of the most serious nutritional problems confronting the United States and the world today. An understanding of the mechanisms operative in the control of uptake and utilization of iron is essential to develop suitable prophylactic and therapeutic strategies. Iron excess can also be a serious hea... | ['Alcoholism', 'Anemia, Hypochromic', 'Carbohydrate Metabolism', 'Child', 'Female', 'Ferrous Compounds', 'Hemosiderosis', 'Humans', 'Iron', 'Iron Chelating Agents', 'Liver Diseases', 'Male', 'Siderosis'] | 1,252,066 | [['C25.775.100.250', 'F03.900.100.350'], ['C15.378.071.196'], ['G02.111.158', 'G03.191'], ['M01.060.406'], ['D01.490.200'], ['C18.452.565.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D27.505.519.914.500.410', 'D27.720.832.500.410'], ['C06.552']... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spontaneous resistance to acute T-cell leukaemias in TCRV gamma 1.1J gamma 4C gamma 4 transgenic mice. | The concept of tumour surveillance implies that specific and non-specific components of the immune system eliminate tumours in the early phase of malignancy. The immunological mechanisms that control growth of preneoplastic cells are, however, not known. T cells expressing gamma delta T-cell receptors (TCR) were first ... | ['3T3 Cells', 'Animals', 'Hybridomas', 'Immunity, Innate', 'Leukemia-Lymphoma, Adult T-Cell', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Mycobacterium bovis', 'Receptors, Antigen, T-Cell, gamma-delta', 'T-Lymphocytes', 'Tumor Cells, Cultured'] | 7,746,326 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['A11.251.353.485', 'A11.251.600.485'], ['G12.450.564'], ['C04.557.337.428.580.100', 'C15.604.515.560.575.100', 'C20.683.515.528.582.100'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term clinical outcomes of peritoneal dialysis patients: 9-year experience of a single center from north India. | OBJECTIVE: There is a paucity of published data on the outcome of maintenance peritoneal dialysis (PD) since the initiation of continuous ambulatory PD (CAPD) in India in 1991. The purpose of this study is to report long-term clinical outcomes of PD patients at a single center.DESIGN: Retrospective study.SETTING: A gov... | ['Aged', 'Aged, 80 and over', 'Female', 'Follow-Up Studies', 'Humans', 'India', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Peritoneal Dialysis, Continuous Ambulatory', 'Retrospective Studies', 'Survival Rate', 'Tertiary Care Centers', 'Treatment Outcome'] | 24,385,327 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E02.760.106.500', 'E02.870.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Estimation of the contribution of norketamine to ketamine-induced acute pain relief and neurocognitive impairment in healthy volunteers. | BACKGROUND: The N-methyl-D-aspartate receptor antagonist ketamine is metabolized in the liver into its active metabolite norketamine. No human data are available on the relative contribution of norketamine to ketamine-induced analgesia and side effects. One approach to assess the ketamine and norketamine contributions ... | ['Acute Pain', 'Adolescent', 'Adult', 'Analgesics', 'Cognition', 'Hot Temperature', 'Humans', 'Ketamine', 'Male', 'Memory', 'Pain Management', 'Pain Measurement', 'Psychomotor Performance', 'Reaction Time', 'Reference Values', 'Single-Blind Method', 'Young Adult'] | 22,692,377 | [['C23.888.592.612.081'], ['M01.060.057'], ['M01.060.116'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['F02.463.188'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surveying Care Teams after in-Hospital Deaths to Identify Preventable Harm and Opportunities to Improve Advance Care Planning. | BACKGROUND: Reviewing in-hospital deaths is one way of learning how to improve the quality and safety of care. Postdeath surveys sent to the care team for patients who died may have a role in identifying opportunities for improvement. As part of a quality improvement initiative, a postdeath care team survey was develop... | ['Advance Care Planning', 'Hospital Mortality', 'Hospitals', 'Humans', 'Patient Safety', 'Quality Improvement', 'Quality of Health Care', 'Surveys and Questionnaires'] | 29,389,464 | [['N04.590.233.624.124'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.135.060.075.399'], ['J01.293.754', 'N04.761.744'], ['N04.761', 'N05.715'], ['E05.318.308.980', 'N05.715.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Pre-operative isotope liver scanning in clinicopathological staging of patients with large bowel cancer. | Isotope liver scanning is an accurate technique for detecting liver metastases from large bowel cancer. In this retrospective study of patients who had a resection for bowel cancer, the accuracy of liver scanning was 95%. However, the scan accuracy as defined by median survival time was insufficient to detect liver met... | ['Actuarial Analysis', 'Aged', 'Colonic Neoplasms', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Neoplasm Staging', 'Predictive Value of Tests', 'Radionuclide Imaging', 'Rectal Neoplasms', 'Retrospective Studies', 'Technetium Tc 99m Sulfur Colloid'] | 3,475,059 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['M01.060.116.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of miR-106a in gastric carcinoma and its clinical significance. | BACKGROUND: MicroRNAs (miRNAs) play important roles in carcinogenesis. miRNA-106a (miR-106a) has oncogenic activity in humans, and often has altered expression. The clinical significance of miR-106a in the diagnosis of gastric carcinoma is poorly understood.METHODS: The level of miR-106a in 55 gastric carcinoma and 17 ... | ['Biomarkers', 'Cell Line, Tumor', 'E2F1 Transcription Factor', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'MicroRNAs', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Retinoblastoma Protein', 'Stomach Neoplasms', 'Up-Regulation'] | 18,996,365 | [['D23.101'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.360.024.328.049', 'D12.776.157.057.158.049', 'D12.776.476.024.420.049', 'D12.776.660.769.049', 'D12.776.930.211.500'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity. | Regulatory factor X 7 (Rfx7) is an uncharacterized transcription factor belonging to a family involved in ciliogenesis and immunity. Here, we found that deletion of Rfx7 leads to a decrease in natural killer (NK) cell maintenance and immunity in vivo. Genomic approaches showed that Rfx7 coordinated a transcriptional ne... | ['Animals', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Chimera', 'Energy Metabolism', 'Gene Regulatory Networks', 'Immunity, Cellular', 'Immunity, Innate', 'Interleukin-15', 'Janus Kinases', 'Killer Cells, Natural', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Regulatory Factor X1', 'Signal Transduc... | 29,967,452 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['B05.200'], ['G03.295'], ['G05.360.080.689.360'], ['G12.450.050.400'], ['G12.450.564'], ['D12.644.276.374.465.515', 'D12.776.467.374.465.515', 'D23.529.374.465.515'], ['D08.811.913.696.620.682.725.124', 'D12.776.476.393'], ['A11.118.637.55... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence valued and used by health promotion practitioners. | The use of evidence has become a foundational part of health promotion practice. Although there is a general consensus that adopting an evidence-based approach is necessary for practice, disagreement remains about what types of evidence practitioners should use to guide their work. An empirical understanding of how pra... | ['Communication', 'Data Accuracy', 'Evidence-Based Practice', 'Grounded Theory', 'Health Promotion', 'Humans', 'New South Wales', 'Research Design'] | 25,502,964 | [['F01.145.209', 'L01.143'], ['E05.318.308.028', 'E05.318.370.725.250', 'L01.399.250.202', 'N05.715.360.300.202', 'N05.715.360.325.685.250'], ['H02.249'], ['H01.770.644.241.424'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['E... | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Purification and characterization of Leydig cells from rat testes. | An LH-responsive Leydig cell preparation (containing 6+/-2% Leydig cells) was obtained by collagenase treatment of rat testis. Centrifugation of this cell preparation through a 13% Ficoll solution for 10 min at 1500 g resulted in a four times purification of the Leydig cells, with a concomitant increases in steroidogen... | ['Albumins', 'Animals', 'Cell Separation', 'Centrifugation', 'Centrifugation, Density Gradient', 'Dextrans', 'Dose-Response Relationship, Drug', 'Esterases', 'Ficoll', 'Hydroxysteroid Dehydrogenases', 'Leydig Cells', 'Luteinizing Hormone', 'Male', 'Microbial Collagenase', 'Osmolar Concentration', 'Rats', 'Spermatogenes... | 185,309 | [['D12.776.034'], ['B01.050'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.181'], ['E05.181.724.336', 'E05.196.941.336'], ['D05.750.078.562.272', 'D09.698.365.272'], ['G07.690.773.875', 'G07.690.936.500'], ['D08.811.277.352'], ['D09.698.330'], ['D08.811.682.047.436'], ['A05.360.444.849.513', 'A06.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phenobarbital-induced hepatocellular proliferation: anti-bromodeoxyuridine and anti-proliferating cell nuclear antigen immunocytochemistry. | We report modifications to immunocytochemical detection procedures for proliferating cell nuclear antigen (PCNA) which permit its identification in liver samples previously fixed for BrdU immunocytochemistry. Both methods have been used for the assessment of phenobarbital-induced cell proliferation in rat liver. The di... | ['Animals', 'Bromodeoxyuridine', 'Histocytological Preparation Techniques', 'Immunohistochemistry', 'Liver', 'Mitosis', 'Nuclear Proteins', 'Phenobarbital', 'Proliferating Cell Nuclear Antigen', 'Rats', 'Rats, Wistar'] | 8,093,255 | [['B01.050'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['E01.370.225.500.620', 'E01.370.225.750.600', 'E05.200.500.620', 'E05.200.750.600'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A cross-sectional study of 329 farms in England to identify risk factors for ovine clinical mastitis. | The aims of this study were to estimate the incidence rate of clinical mastitis (IRCM) and identify risk factors for clinical mastitis in suckler ewes to generate hypotheses for future study. A postal questionnaire was sent to 999 randomly selected English sheep farmers in 2010 to gather data on farmer reported IRCM an... | ['Animals', 'Cross-Sectional Studies', 'England', 'Female', 'Incidence', 'Mastitis', 'Retrospective Studies', 'Risk Factors', 'Sheep', 'Sheep Diseases'] | 26,809,634 | [['B01.050'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.363.300'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C13.703.844.603', 'C17.800.090.968'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Evaluation of the mutagenic potential of ubidecarenone using three short-term assays. | Addition of ubidecarenone, coenzyme Q(10) (CoQ(10)), to foods has been proposed for its nutritive value. Ubidecarenone is present naturally in a number of foods, including meats (e.g., beef, chicken) and fish (e.g., herring, rainbow trout), and on average, people are estimated to consume 2-20 mg/day of this metabolical... | ['Animals', 'Antioxidants', 'Chromosome Aberrations', 'Coenzymes', 'Escherichia coli', 'Humans', 'Male', 'Mice', 'Micronucleus Tests', 'Mutagenicity Tests', 'Mutagens', 'Mutation', 'Salmonella typhimurium', 'Ubiquinone'] | 16,198,039 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C23.550.210', 'G05.365.590.175'], ['D08.211'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.560.598'], ['E05.393.560', 'E05.94... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hyperascyrones A-H, polyprenylated spirocyclic acylphloroglucinol derivatives from Hypericum ascyron Linn. | Eight polyprenylated spirocyclic acylphloroglucinol derivatives (PSAPs), hyperascyrones A-H, were isolated from the aerial parts of Hypericum ascyron Linn., together with six known analogs. Their structures were established by spectroscopic analyses including HRESIMS, 1D and 2D NMR, and their absolute configurations we... | ['Anti-HIV Agents', 'Antineoplastic Agents, Phytogenic', 'Drug Screening Assays, Antitumor', 'Drugs, Chinese Herbal', 'HIV-1', 'HL-60 Cells', 'Humans', 'Hypericum', 'Inhibitory Concentration 50', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Phloroglucinol', 'Spiro Compounds'] | 25,800,107 | [['D27.505.954.122.388.077.088'], ['D27.505.954.248.179'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D20.215.784.500.350', 'D26.335'], ['B04.820.650.589.650.350.400'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The "Health Benefits" of Moderate Drinking in Older Adults may be Better Explained by Socioeconomic Status. | Objectives: To assess whether a relationship between alcohol use and health exists for older adults before and after controlling for proxy and full indicators of socioeconomic status (SES).Method: Secondary analysis of data from 2,908 participants in the New Zealand Longitudinal Study of Ageing (2012) completing measur... | ['Age Factors', 'Aged', 'Alcohol Drinking', 'Educational Status', 'Female', 'Health Status', 'Humans', 'Income', 'Longitudinal Studies', 'Male', 'New Zealand', 'Sex Factors', 'Social Class'] | 27,927,745 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.145.317.269'], ['N01.824.196'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['Z01.63... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Antisense oligodeoxynucleotides to G-protein alpha-subunit subclasses identify a transductional requirement for the modulation of normal feeding dependent on G alpha OA subunit. | A variety of G-protein-coupled receptors are proposed to participate in the modulation of ingestive behavior and in the mode of action of antiobesity drugs. In the present study, we investigated the involvement of G-protein alpha-subunit subclasses (molecular transducers of multiple chemical signals) in the control of ... | ['Animals', 'Cerebral Ventricles', 'Feeding Behavior', 'GTP-Binding Proteins', 'Immunoblotting', 'Infusions, Parenteral', 'Male', 'Molecular Sequence Data', 'Oligonucleotides, Antisense', 'Peptide Fragments', 'Rats', 'Rats, Wistar', 'Reference Values', 'Signal Transduction', 'Thionucleotides', 'Ventromedial Hypothalami... | 8,774,947 | [['B01.050'], ['A08.186.211.140'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['E05.478.566.320', 'E05.601.470.320'], ['E02.319.267.510'], ['L01.453.245.667'], ['D13.150.480', 'D13.444.600.150.640', 'D13.695.578.424.480', 'D27.720.470.530.600.150.640'], ['D12.... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of a process for large-scale purification of C-phycocyanin from Synechocystis aquatilis using expanded bed adsorption chromatography. | In this paper a large and scaleable method for purification of C-phycocyanin (C-PC) from the cyanobacteria Synechocystis aquatilis has been developed. Phycobiliproteins are extracted from the cells by osmotic shock and separated by passing the centrifuged cell suspension through an expanded bed adsorption chromatograph... | ['Adsorption', 'Chromatography, DEAE-Cellulose', 'Chromatography, High Pressure Liquid', 'Electrophoresis, Polyacrylamide Gel', 'Phycocyanin', 'Spectrometry, Fluorescence', 'Synechocystis', 'Viscosity'] | 21,292,571 | [['G01.030', 'G02.020'], ['E05.196.181.400.383.349'], ['E05.196.181.400.300'], ['E05.196.401.402', 'E05.301.300.319'], ['D05.500.562.488.490.500.500.755', 'D08.811.600.710.490.500.500.755', 'D12.776.765.650', 'D23.767.690'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['B03.280.750', 'B03.440.475.100.750'], ['G02.9... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence and prognostic importance of lymph node metastases in dogs with appendicular osteosarcoma: 228 cases (1986-2003). | OBJECTIVE: To determine the incidence of regional lymph node metastasis in dogs with appendicular osteosarcoma and determine whether regional lymph node metastasis was associated with shortened disease-free interval or survival time.DESIGN: Retrospective study.ANIMALS: 228 dogs with appendicular osteosarcoma in which r... | ['Amputation', 'Animals', 'Disease-Free Survival', 'Dog Diseases', 'Dogs', 'Extremities', 'Female', 'Incidence', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Osteosarcoma', 'Prognosis', 'Retrospective Studies', 'Survival Analysis', 'Time Factors'] | 15,844,430 | [['E04.555.080'], ['B01.050'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['A01.378'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Annexin A3 as a Prognostic Biomarker for Breast Cancer: A Retrospective Study. | To validate the correlation between ANXA3 expression and prognosis in breast cancer, a retrospective study encompassing 309 breast cancer patients was performed. The expression of ANXA3 was determined by the immunohistochemical examination of tissue sections by the Max Vision™ method. The ANXA3 levels in the patient sa... | ['Adult', 'Aged', 'Annexin A3', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Proteins', 'Retrospective Studies', 'Survival Rate'] | 28,497,041 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.352.640.050', 'D12.776.157.125.050.070'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.372.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Recurrent pigmented villonodular synovitis (PVNS)]. | AIM: The pigmented vilionodular synovitis (PVNS) is a tumour like disease of unknown origin that often shows recurrence. The pathogenesis is still unknown and therefore the question of the right therapy is not resolved.MATERIAL: With a case report of a patient with recurrence after two arthroscopic synovectomies, PVNS ... | ['Adult', 'Female', 'Humans', 'Postoperative Complications', 'Radiography', 'Recurrence', 'Reoperation', 'Synovectomy', 'Synovial Membrane', 'Synovitis, Pigmented Villonodular'] | 11,558,057 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E01.370.350.700'], ['C23.550.291.937'], ['E04.690'], ['E04.555.640'], ['A02.835.583.443.800'], ['C04.557.450.565.380.690.500', 'C05.550.870.445.500', 'C05.651.869.762.500']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Better posttransplant outcome with fludarabine based conditioning in multitransfused fanconi anemia patients who underwent peripheral blood stem cell transplantation. | Several investigators have been looking for less toxic conditioning regimen for stem cell transplantation in Fanconi anemia (FA) patients because of sensitivity to DNA cross-linking agents and tendency to malignancy. We report 16 multitransfused FA patients who underwent peripheral stem cell transplantation from 13 rel... | ['Adolescent', 'Antilymphocyte Serum', 'Antineoplastic Combined Chemotherapy Protocols', 'Child', 'Child, Preschool', 'Combined Modality Therapy', 'Cyclophosphamide', 'Fanconi Anemia', 'Female', 'Graft vs Host Disease', 'Humans', 'Male', 'Peripheral Blood Stem Cell Transplantation', 'Radiotherapy', 'Transplantation Con... | 19,564,748 | [['M01.060.057'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['M01.060.406'], ['M01.060.406.448'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.70... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins. | RNA-protein interactions are fundamental to gene expression. Thus, the molecular basis for the sequence dependence of protein-RNA recognition has been extensively studied experimentally. However, there have been very few computational studies of this problem, and no sustained attempt has been made towards using computa... | ['Algorithms', 'Binding Sites', 'Kinetics', 'Models, Molecular', 'Nucleic Acid Conformation', 'Protein Binding', 'Protein Structure, Tertiary', 'RNA', 'RNA-Binding Proteins', 'Thermodynamics'] | 18,005,254 | [['G17.035', 'L01.224.050'], ['G02.111.570.120'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['G02.111.570.820.486', 'G05.360.580'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.610'], ['D13.444.735'], ['D12.776.157.725', 'D12.776.664.962'], ['G01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Determination of isosorbide-5-mononitrate in tablets by differential pulse polarography. | A differential pulse polarographic method requiring little sample separation was developed for the determination of isosorbide-5-mononitrate in tablet dosage form with the standard addition technique and without interference from common excipients. Britton-Welford buffer (pH 3.0) was used as the supporting electrolyte,... | ['Indicators and Reagents', 'Isosorbide Dinitrate', 'Polarography', 'Tablets'] | 2,726,993 | [['D27.720.470.410'], ['D02.033.800.813.480.500', 'D09.853.813.480.500'], ['E05.196.749', 'E05.301.700'], ['D26.255.830']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Experimental studies on oral administration of nitrosourea anti-tumor agent, MCNU]. | Experimental studies with orally administered MCNU, a water-soluble nitrosourea, yielded the following results. MCNU produced a significant increase in life span, and 60-day survivors were observed by various schedules in L1210 leukemia. The therapeutic ratios of MCNU were almost similar to those of CCNU. With Lewis lu... | ['Administration, Oral', 'Animals', 'Antineoplastic Agents', 'Dogs', 'Female', 'Half-Life', 'Leukemia L1210', 'Liver Neoplasms, Experimental', 'Lung Neoplasms', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neoplasms, Experimental', 'Nitrosourea Compounds', 'Streptozocin'] | 6,234,861 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.248'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.910.405'], ['C04.557.337.372.594', 'C04.619.531.594'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Designing and tuning magnetic resonance with exchange interaction. | Exchange interaction at the interface between magnetic layers exhibits significant contribution to the magnetic resonance frequency. The in situ tuning of the resonance frequency, as large as 10 GHz, is demonstrated in a spintronics microwave device through manipulating the interface exchange interaction. | ['Acoustics', 'Magnetic Phenomena', 'Optical Phenomena'] | 25,572,962 | [['H01.671.031'], ['G01.358'], ['G01.590']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential anatomical location of [3H]-N,n-propylnorapomorphine and [3H]-spiperone binding sites in the striatum and substantia nigra of the rat. | Specific [3H]-spiperone and [3H]-N,n-propylnorapomorphine (NPA) binding was measured in striatum and substantia nigra of the rat following unilateral 6-hydroxydopamine (6-OHDA) lesions of the medial forebrain bundle, kainic acid lesions of the substantia nigra or striatum, and following decortication. Binding sites lab... | ['Animals', 'Apomorphine', 'Butyrophenones', 'Corpus Striatum', 'Female', 'Hydroxydopamines', 'Oxidopamine', 'Rats', 'Rats, Inbred Strains', 'Receptors, Dopamine', 'Spiperone', 'Substantia Nigra', 'Tritium'] | 6,418,246 | [['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['D02.522.352'], ['A08.186.211.200.885.287.249.487'], ['D02.092.311.342.478', 'D02.455.426.559.389.657.166.175.342.478'], ['D02.092.311.342.478.650', 'D02.455.426.559.389.657.166.175.342.478.650'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prospects and limitations of different registration modalities in electromagnetic ENT navigation. | The present study examined electromagnetic tracking technology for ENT navigation. Five different registration modalities were compared and navigation accuracy was assessed. Four skull models were individually fabricated with a three-dimensional printer, based on patients' computer tomography datasets. Individual silic... | ['Anatomic Landmarks', 'Bone Screws', 'Diagnosis, Computer-Assisted', 'Electromagnetic Fields', 'Fiducial Markers', 'Humans', 'Imaging, Three-Dimensional', 'Otolaryngology', 'Skull', 'Titanium', 'Tomography, X-Ray Computed'] | 27,149,874 | [['A01.111'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E01.158', 'L01.313.500.750.100.158'], ['G01.358.500.260', 'G01.358.750.500'], ['E05.978.808.249', 'E07.695.237', 'E07.710.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['H02.403.8... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
A simple direct assay of 3',5'-cyclic nucleotide phosphodiesterase activity based on the use of polyacrylamide-bononate affinity gel chromatography. | A rapid, simple, and direct assay for 3',5'-cyclic nucleotide phospho-diesterase activity is based on the effective separation of cyclic AMP, cyclic GMP or cyclic CMP from their corresponding 5'-nucleotides and nucleosides by chromatography on a polyacrylamide-boronate gel. The affinity of the boronate residue for cis-... | ["3',5'-Cyclic-AMP Phosphodiesterases", "3',5'-Cyclic-GMP Phosphodiesterases", 'Adenosine Deaminase', 'Animals', 'Boronic Acids', 'Chromatography, Affinity', 'Kinetics', 'Nucleosides', 'Nucleotidases', 'Nucleotides, Cyclic', 'Rats', 'Ribonucleotides', 'Tissue Distribution'] | 220,290 | [['D08.811.277.352.640.150', 'D12.644.360.008', 'D12.776.476.008'], ['D08.811.277.352.640.155', 'D12.644.360.009', 'D12.776.476.009'], ['D08.811.277.151.486.075'], ['B01.050'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['E05.196.181.400.170'], ['G01.374.661', 'G02.111.490'], ['D09.408.595', 'D13.570'], ['D08.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Toxicity associated with PD-1 blockade after allogeneic haematopoietic cell transplantation. | Cancer immunotherapy with immune checkpoint inhibitors (ICIs) such as programmed death ligand-1 (PD-L1) blockers offers pronounced clinical benefit with durable responses and a manageable safety profile. Patients with a high risk of immune-related adverse events are generally excluded from clinical trials testing ICI t... | ['Adult', 'Aged', 'Allografts', 'Antibodies, Monoclonal', 'Antineoplastic Agents', 'Carcinoma, Renal Cell', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Hodgkin Disease', 'Humans', 'Immunologic Factors', 'Male', 'Melanoma', 'Middle Aged', 'Nivolumab', 'Programmed Cell Death 1 Receptor', 'Retrospective Studies'... | 31,707,719 | [['M01.060.116'], ['M01.060.116.100'], ['A01.941.500'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Von Meyenburg complexes. case report]. | Von Meyenburg complexes is one of the polycystic liver diseases, characterized by bile duct hamartoma. These cysts come from the biliary tract but the cysts do not communicate with them. Because of asymptomatic course of the lesions usually are diagnosed in the course of diagnostic for another reason. It is not possibl... | ['Adult', 'Bile Ducts, Intrahepatic', 'Cysts', 'Female', 'Humans', 'Liver Diseases', 'Magnetic Resonance Imaging', 'Tomography, X-Ray Computed'] | 29,478,992 | [['M01.060.116'], ['A03.159.183.158', 'A03.620.150'], ['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['E01.370.350.825.500'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Co₃O₄ Nanosheets Anchored on SiO₂ Nanospheres for Non-Enzymatic Glucose Sensor. | The electrochemical sensing performance is sensitive to the surface area. To achieve superior performance, we design and anchor Co3O4 nanosheets on the surface of SiO2 nanospheres via a simple solvothermal method, which possess large sensing interface and exposed catalytic sites due to the 2D structure and edge termina... | ['Biosensing Techniques', 'Catalysis', 'Cobalt', 'Electrochemical Techniques', 'Glucose', 'Limit of Detection', 'Nanospheres', 'Nanostructures', 'Oxides', 'Silicon Dioxide'] | 29,954,568 | [['E05.601.043'], ['G02.130'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['E05.301'], ['D09.947.875.359.448'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E07.595', 'J01.637.512.600.612'], ['J01.637.512'], ['D01.248.497.158.685', 'D01.650.550'], ['D01.578.750', 'D01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
NG-monomethyl L-arginine inhibits endothelium-derived relaxing factor-stimulated cyclic GMP accumulation in cocultures of endothelial and vascular smooth muscle cells by an action specific to the endothelial cell. | The effect of NG-monomethyl L-arginine (LNMMA), an analogue of L-arginine (a proposed precursor of endothelium-derived relaxing factor [EDRF]), on EDRF release from bovine pulmonary artery endothelial cells was investigated using endothelial cell-vascular smooth muscle cocultures and a superfused column containing endo... | ['Adenosine Triphosphate', 'Animals', 'Arginine', 'Bradykinin', 'Calcimycin', 'Cattle', 'Cells, Cultured', 'Cyclic GMP', 'Endothelium, Vascular', 'Melitten', 'Muscle, Smooth, Vascular', 'Nitric Oxide', 'Pulmonary Artery', 'omega-N-Methylarginine'] | 2,170,053 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['D03.633.100.221... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma. | BACKGROUND & AIMS: Early detection of hepatocellular carcinoma (HCC) is critical for successful treatment. However, the differential diagnosis between HCC and benign hepatic lesions is sometimes difficult and new biochemical markers for HCC are required. It has been reported that glypican-3 (GPC3) messenger RNA (mRNA) ... | ['Animals', 'Antibodies, Monoclonal', 'Biomarkers, Tumor', 'Blotting, Western', 'Carcinoma, Hepatocellular', 'Female', 'Glypicans', 'Heparan Sulfate Proteoglycans', 'Humans', 'Immunohistochemistry', 'Liver', 'Liver Neoplasms', 'Mice', 'Mice, Inbred BALB C', 'Tumor Cells, Cultured', 'alpha-Fetoproteins'] | 12,851,874 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.101.140'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Loss of insulin-like growth factor I receptor-dependent expression of p107 and cyclin A in cells that lack the extracellular matrix protein secreted protein acidic and rich in cysteine. | The extracellular matrix-associated glycoprotein secreted protein acidic and rich in cysteine (SPARC) has been implicated in the control of cell proliferation during tissue remodeling, wound healing, and malignant development. Here, we describe a novel mechanism through which SPARC influences cell cycle progression in ... | ['Animals', 'Cell Division', 'Cells, Cultured', 'Cyclin A', 'Cysteine', 'Extracellular Matrix', 'Fibroblasts', 'Gene Expression Regulation', 'Hypoglycemic Agents', 'Insulin', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nuclear Proteins', 'Osteonectin', 'Platelet-Derived Growth Factor', 'Receptor, IGF Type 1', 'Ret... | 10,593,648 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D12.644.360.262.100', 'D12.776.167.218.100', 'D12.776.476.262.100'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['A11.284.295.310'], ['A11.329.228'], ['G05.308'], ['D27.505.696.422']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacterial Microcolonies in Gel Beads for High-Throughput Screening of Libraries in Synthetic Biology. | Synthetic biologists increasingly rely on directed evolution to optimize engineered biological systems. Applying an appropriate screening or selection method for identifying the potentially rare library members with the desired properties is a crucial step for success in these experiments. Special challenges include su... | ['Cells, Immobilized', 'Escherichia coli', 'Gene Library', 'Synthetic Biology'] | 28,803,463 | [['A11.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.325'], ['H01.158.273.904', 'J01.293.069.500']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Teratogenic effects of neonatal arenavirus infection on the developing rat cerebellum are abrogated by passive immunotherapy. | The effects of viral infection on the developing nervous system and the potential of passive immunotherapy to protect against infection were examined. When 4-day-old Lewis rats were injected intracerebrally with lymphocytic choriomeningitis virus (LCMV) the majority of stem cells within the external granular layer of t... | ['Animals', 'Animals, Newborn', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Antibody Specificity', 'Binding, Competitive', 'Brain', 'Cerebellum', 'Choroid Plexus', 'Enzyme-Linked Immunosorbent Assay', 'Ependyma', 'Female', 'Immunity, Maternally-Acquired', 'Immunohistochemistry', 'Immunotherapy, Adoptive', 'Lymphocy... | 8,249,289 | [['B01.050'], ['B01.050.050.282'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G12.100'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A08.186.211'], ['A08.186.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of the detection of urinary tract infection by the reagent strip method in hospitalized patients]. | Asymptomatic urinary tract infections (UTI) are frequent in hospital patients. Two prospective studies were carried out to evaluate the reagent strip method used to detect these infections. The diagnosis of UTI rested on cytobacteriological examination of urine. Detection by reagent strip was performed either in the mi... | ['France', 'Hospitalization', 'Humans', 'Prevalence', 'Prospective Studies', 'Reagent Strips', 'Urinary Tract Infections'] | 2,141,122 | [['Z01.542.286'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['D27.505.25... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
PCR-based methods for the detection of L1014 kdr mutation in Anopheles culicifacies sensu lato. | BACKGROUND: Anopheles culicifacies s.l., a major malaria vector in India, has developed widespread resistance to DDT and is becoming resistant to pyrethroids-the only insecticide class recommended for the impregnation of bed nets. Knock-down resistance due to a point mutation in the voltage gated sodium channel at L101... | ['Alleles', 'Animals', 'Anopheles', 'Base Sequence', 'DDT', 'DNA Primers', 'Dipeptides', 'Genes, Insect', 'Genotype', 'India', 'Insecticide Resistance', 'Molecular Sequence Data', 'Mutation', 'Point Mutation', 'Polymerase Chain Reaction', 'Pyrethrins', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Seque... | 19,594,947 | [['G05.360.340.024.340.030'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.455.526.439.255'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D12.644.456.345'], ['G05.360.340.024.340.340', 'G05.360.340.357.500'], ['G... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Double-blind comparison of moclobemide and tranylcypromine in depression. | Moclobemide is the first of a new generation of reversible inhibitors of monoamine oxidase-A (RIMA) with no clinically relevant potentiation of the hypertensive actions of dietary tyramine. The present study was conducted to compare the efficacy and safety of moclobemide with an established irreversible monoamine oxida... | ['Adult', 'Benzamides', 'Depressive Disorder', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Middle Aged', 'Moclobemide', 'Monoamine Oxidase Inhibitors', 'Psychiatric Status Rating Scales', 'Tranylcypromine'] | 8,127,928 | [['M01.060.116'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['F03.600.300'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.065.277.600', 'D02.241.223.100.100.600', 'D02.241.22... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Craniofacial morphology of the first Americans: Pattern and process in the peopling of the New World. | The peopling of the New World has been the focus of anthropological attention since the last century. Proponents of multiple migration models have claimed that patterns of variation among extant New World populations reflect ancient, discrete migrations to the Americas during the terminal Pleistocene. Although multiple... | ['Anthropometry', 'Asia', 'Biological Evolution', 'Emigration and Immigration', 'Face', 'Founder Effect', 'Genetic Variation', 'Humans', 'Indians, North American', 'Multivariate Analysis', 'North America', 'Skull'] | 10,601,986 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['Z01.252'], ['G05.045', 'G16.075'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['A01.456.505'], ['G05.285'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['E05.318.740.150.500', 'N05.71... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Modulation of GABA-mediated synaptic transmission by endogenous zinc in the immature rat hippocampus in vitro. | 1. Intracellular recordings from postnatal 2- to 12-day-old (P2-12) rat hippocampal CA3 pyramidal neurones exhibited spontaneous synaptic potentials mediated by GABAA receptors. These potentials can be separated on the basis of amplitude into two classes which are referred to as small and large. 2. The large depolarizi... | ['6-Cyano-7-nitroquinoxaline-2,3-dione', 'Action Potentials', 'Aging', 'Alanine', 'Animals', 'Animals, Newborn', 'Bicuculline', 'Cations, Divalent', 'Chelating Agents', 'Electric Stimulation', 'Evoked Potentials', 'Hippocampus', 'Histidine', 'In Vitro Techniques', 'Iron Chelating Agents', 'Pyramidal Tracts', 'Pyridones... | 7,965,838 | [['D03.633.100.857.160'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G07.345.124'], ['D12.125.042'], ['B01.050'], ['B01.050.050.282'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['D01.248.497.300.333'], ['D27.505.519.914.500', 'D27.720.832.500'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of MALT and non-MALT primary large cell lymphoma of the stomach: does histologic evidence of MALT affect chemotherapy response? | BACKGROUND: Although the clinicopathologic features of low grade gastric MALToma (lymphoma of mucosa-associated lymphoid tissue) recently have been well delineated, the significance of identifying histologic evidence of MALT origin in a primary high grade gastric lymphoma is less clear. The authors sought to address th... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Female', 'Humans', 'Lymphoma, B-Cell, Marginal Zone', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Retrospective Studies', 'Stomach Neoplasms', 'Survival Analysis', 'Treatment Outcome'] | 11,148,559 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480.150.570', 'C15.604.515.569.480.150.570', 'C20.683.515.761.480.150.570'], ['C04.557.386.480.150.585', 'C15.604.515.569.480.150.585', 'C20.683.515.761.480.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Investigation of the persistence of levamisole and oxyclozanide in milk and fate in cheese. | In this study, dairy cows (n = six) were treated with an oral combination product containing levamisole (5 mg/kg body weight, (bw)) and oxyclozanide (10 mg/kg bw). Animals were milked twice daily up to day 16 post-treatment. Milk samples were subsequently analyzed by ultraperformance liquid chromatography coupled to ta... | ['Animals', 'Antinematodal Agents', 'Cattle', 'Cheese', 'Drug Residues', 'Food Contamination', 'Kinetics', 'Levamisole', 'Milk', 'Oxyclozanide'] | 21,058,728 | [['B01.050'], ['D27.505.954.122.250.075.080'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.200.500.444', 'G07.203.300.350.300.444', 'J02.350.500.444', 'J02.500.350.300.444'], ['N06.850.460.200.250'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['G01.374.661', 'G02.111.490'], ['D02.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Fiberoptic examination of the inferior vena cava during circulatory arrest for complete removal of renal cell carcinoma thrombus. | Renal cell carcinoma is known to invade the inferior vena cava and may extend its entire length. Profound hypothermic circulatory arrest has been demonstrated to be a very effective technique to facilitate removal of tumor thrombus from the cava while limiting the amount of blood loss. We describe an innovative method ... | ['Bronchoscopes', 'Carcinoma, Renal Cell', 'Fiber Optic Technology', 'Heart Arrest, Induced', 'Humans', 'Intraoperative Period', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Radiography', 'Thrombosis', 'Vena Cava, Inferior'] | 2,353,309 | [['E07.230.220.090', 'E07.858.240.090'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['H01.671.617.249'], ['E04.100.376.374', 'E04.928.220.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Mesoporous-activated carbon prepared from chitosan flakes via single-step sodium hydroxide activation for the adsorption of methylene blue. | In this work, mesoporous-activated carbon (CSAC) was prepared from chitosan flakes (CS) via single-step sodium hydroxide activation for the adsorption of methylene blue (MB). CSAC was prepared using different impregnation ratios of NaOH:CS (1:1, 2:1, 3:1, and 4:1) at 800°C for 90min. The adsorption performance of CSAC ... | ['Adsorption', 'Charcoal', 'Chitosan', 'Hydrogen-Ion Concentration', 'Kinetics', 'Methylene Blue', 'Porosity', 'Sodium Hydroxide', 'Temperature', 'Water Pollutants, Chemical'] | 28,147,233 | [['G01.030', 'G02.020'], ['D01.268.150.150'], ['D05.750.078.139.500', 'D09.698.211.500'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D02.886.369.517', 'D03.633.300.783.517'], ['G01.374.710'], ['D01.045.250.750', 'D01.248.497.158.459.475', 'D01.857.745'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.7... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protection by taurine against adriamycin-induced proteinuria and hyperlipidemia in rats. | Taurine was used in the present study to evaluate its beneficial effects against proteinuria and hyperlipidemia associated with nephrotic syndrome. Rats made nephrotic with adriamycin had a high excretion of protein, albumin, and N-acetyl-beta-D-glucosaminidase compared with nonnephrotic rats. Nephrotic rats manifested... | ['Acetylglucosaminidase', 'Animals', 'Antioxidants', 'Body Weight', 'Doxorubicin', 'Hyperlipidemias', 'Lipid Peroxides', 'Lipoprotein Lipase', 'Liver', 'Nephrotic Syndrome', 'Oxidation-Reduction', 'Phosphatidylcholine-Sterol O-Acyltransferase', 'Proteinuria', 'Rats', 'Rats, Wistar', 'Taurine'] | 9,182,303 | [['D08.811.277.450.483.180.500'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retroperitoneal fibrosis during treatment with methydopa. | Retroperitoneeal fibrosis (R.P.F.) and a positive direct Coombs test developed in a patient who had received 1.4 kg. of alpha-methyldopa over a period of 5 years. Immunofluorescence microscopy demonstrated deposits of IgG, IgM, and IgA on the collagen fibres of the R.P.F. Biopsy speciments of the temporal artery, the r... | ['Biopsy', 'Collagen', 'Coombs Test', 'Fluorescent Antibody Technique', 'Humans', 'Hypertension', 'Immunoglobulins', 'Kidney', 'Male', 'Methyldopa', 'Microscopy, Electron', 'Middle Aged', 'Retroperitoneal Fibrosis', 'Temporal Arteries'] | 50,510 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E01.370.225.812.735.050.375.150', 'E05.200.812.735.050.375.150', 'E05.478.594.760.050.375.150'], ['E01.370.225.500.607.512.240', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A method to estimate cardiac volume by two-dimensional echocardiograms recorded from one extracorporeal point. | This paper presents a method for estimating the volume of a cardiac region from its oblique sectional images recorded with a sector scanner. The probe of the scanner is attached to the chest wall and an ultrasonic beam is cast from a fixed intercostal space. In a previous paper a method of calculation for the above rec... | ['Cardiac Volume', 'Computers', 'Echocardiography', 'Heart', 'Humans', 'Models, Biological', 'Ultrasonography'] | 7,070,065 | [['G09.330.380.249'], ['L01.224.230.260'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E01.370.350.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Analysis of influencing factors on occupational pressure of medical staff in a third-level first-class hospital of traditional Chinese medicine in Tianjin]. | Objective: To explore the status and influencing factors of occupational pressure among medical staff in a third-level first-class hospital of traditional Chinese medicine in Tianjin, and to provide reference for formulating relevant policies. Methods: From September to October in 2019, doctors, nurses, pharmacists lab... | ['Hospitals', 'Humans', 'Medical Staff', 'Medical Staff, Hospital', 'Medicine, Chinese Traditional', 'Occupational Stress', 'Physician-Patient Relations', 'Surveys and Questionnaires', 'Workload'] | 32,746,574 | [['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.630', 'N02.360.630'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['C24.580', 'F01.145.126.990.734', 'F02.830.900.666'], ['F01.829.401.650.67... | ['Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Borocaptate sodium: a potential boron delivery compound for boron neutron capture therapy evaluated in dogs with spontaneous intracranial tumors. | Borocaptate sodium (Na2B12H11SH) is a boron-carrying compound under consideration for use in boron neutron capture therapy. The biodistribution of boron from borocaptate sodium administration will partly determine boron neutron capture therapy efficacy and normal tissue radiation tolerance. The biodistribution of boron... | ['Animals', 'Boranes', 'Borohydrides', 'Boron', 'Brain Neoplasms', 'Dogs', 'Female', 'Male', 'Neutron Capture Therapy', 'Sulfhydryl Compounds'] | 1,465,427 | [['B01.050'], ['D01.132.105', 'D02.203.087'], ['D01.132.105.050', 'D02.203.087.050'], ['D01.268.513.500'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.815.722.500'], ['D02.886.489']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thymidine esters as substrate analogue inhibitors of angiogenic enzyme thymidine phosphorylase in vitro. | Thymidine phosphorylase (TP) catalyzes the cleavage of thymidine into thymine and 2-deoxy-á-d-ribose-1-phosphate. Elevated activity of TP prevents apoptosis, and induces angiogenesis which ultimately leads to tumor growth and metastasis. Critical role of TP in cancer progression makes it a valid target in anti-cancer r... | ['3T3 Cells', 'Animals', 'Enzyme Inhibitors', 'Escherichia coli', 'Esters', 'Humans', 'Mice', 'Molecular Docking Simulation', 'Thymidine', 'Thymidine Phosphorylase', 'Xanthines'] | 27,955,923 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.595.249', 'L01.224.160.249'], ['D03.383.742.680.705', 'D13.570.230.8... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Humoral immunity to herpes simplex virus type 2 in cervical cancer]. | The analysis of the results of serological studies revealed differences between the number of positively reacting sera from patients with cervical carcinoma and from normal women. The activity of complement-fixing and virus-neutralizing antibodies in the patients' sera and the frequency of their detection were higher t... | ['Adult', 'Antibody Formation', 'Complement Fixation Tests', 'Female', 'Herpes Genitalis', 'Humans', 'Male', 'Middle Aged', 'Neutralization Tests', 'Recurrence', 'Simplexvirus', 'Uterine Cervical Dysplasia', 'Uterine Cervical Neoplasms'] | 6,289,530 | [['M01.060.116'], ['G12.450.050.370.250'], ['E01.370.225.812.735.150', 'E05.200.812.735.150', 'E05.478.594.760.150'], ['C01.221.812.640.350', 'C01.778.640.350', 'C01.925.256.466.382.290', 'C01.925.813.350', 'C12.294.329', 'C13.351.500.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.37... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Temporomandibular ankylosis. A treatment method using the interposition of a Dacron device]. | BACKGROUND: Temporomandibular ankylosis with its multiple anatomo-clinical forms is a relatively rare disease. Its major morphopathological, therapeutical and psychological implications rank it among severe illnesses. Its treatment is exclusively surgical. The major therapeutical indication in ankylosis of type I and I... | ['Adolescent', 'Adult', 'Ankylosis', 'Arthroplasty, Replacement', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Joint Prosthesis', 'Male', 'Oral Surgical Procedures', 'Polyethylene Terephthalates', 'Range of Motion, Articular', 'Retrospective Studies', 'Temporomandibular Joint', 'Temporomandibular Joint Disorders',... | 12,538,917 | [['M01.060.057'], ['M01.060.116'], ['C05.550.069'], ['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400'], ['E04.545', 'E06.645'], ['D05.750.728.764', 'D25.720.728.764', 'J01.637.051.720.728.764'], ['E01.370.600.700'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Favorable Changes in Biomarkers of Potential Harm to Reduce the Adverse Health Effects of Smoking in Smokers Switching to the Menthol Tobacco Heating System 2.2 for 3 Months (Part 2). | INTRODUCTION: Tobacco Heating System (THS) 2.2, a candidate modified-risk tobacco product, aims at offering an alternative to cigarettes for smokers while substantially reducing the exposure to harmful and potentially harmful constituents found in cigarette smoke.METHODS: One hundred and sixty healthy adult US smokers ... | ['Adult', 'Aged', 'Antipruritics', 'Biomarkers', 'Electronic Nicotine Delivery Systems', 'Female', 'Harm Reduction', 'Health Behavior', 'Heating', 'Hot Temperature', 'Humans', 'Male', 'Menthol', 'Middle Aged', 'Risk Assessment', 'Smoke', 'Smokers', 'Smoking', 'Young Adult'] | 31,125,079 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.444.075'], ['D23.101'], ['J01.637.767.500'], ['F01.145.477'], ['F01.145.488'], ['N06.230.150.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Mass fragmentographic determination of endogenous glycine and glutamic acid released in vivo from the pigeon optic tectum. Effect of electric stimulation of a midbrain nucleus. | Various investigations suggest glycine to be an inhibitory transmitter in the pigeon optic lobe in a pathway originating in the nucleus isthmi, pars parvocellularis (Ipc) terminating in the optic tectum. In order to obtain additional evidence for this hypothesis the in vivo release of endogenous glycine in the optic te... | ['Animals', 'Columbidae', 'Electric Stimulation', 'Gas Chromatography-Mass Spectrometry', 'Glutamates', 'Glutamic Acid', 'Glycine', 'Mesencephalon', 'Superior Colliculi'] | 6,116,527 | [['B01.050'], ['B01.050.150.900.248.165.150'], ['E05.723.402'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D12.125.481'], ['A08.186.211.132.659'], ['A08.186.211.132.659.800.816']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Post-kala-azar dermal leishmaniasis (PKDL), HIV and pulmonary tuberculosis. | Post-kala-azar dermal leishmaniasis is usually a sequel to visceral leishmaniasis. A 25-year-old woman presented with hypopigmented maculopapular lesions all over the body for the past 4 years without any previous history of visceral leishmaniasis. She was on treatment for leprosy and pulmonary tuberculosis for the pas... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Female', 'HIV-1', 'Humans', 'Leishmaniasis, Cutaneous', 'Leishmaniasis, Visceral', 'Tuberculosis, Pulmonary'] | 20,925,205 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Notifiable animal diseases diagnosed at the Institute of Veterinary Pathology of the University of Zurich between 1988 and 2004]. | One of the essential tasks of veterinary pathology is the gross and microscopic examination of animals post mortem. Frequently requests are made for the cause of disease or death in the absence of a precise history or an otherwise specific assignment e.g. whether a notifiable disease is involved. The general examinatio... | ['Animal Diseases', 'Animals', 'Autopsy', 'Bacterial Infections', 'Cattle', 'Databases, Factual', 'Goats', 'Horses', 'Mammals', 'Parasitic Diseases, Animal', 'Retrospective Studies', 'Sheep', 'Swine', 'Switzerland', 'Virus Diseases'] | 18,225,409 | [['C22'], ['B01.050'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['C01.150.252'], ['B01.050.150.900.649.313.500.380.271'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.500.380.513'], ['B01.050.150.900.649.313.984.235.472'], ['B01.050.150.900.649'], ['C01.610.701', 'C22.674'], [... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Hyperkalemia after acute metabolic decompensation in two children with vitamin B12-unresponsive methylmalonic acidemia and normal renal function. | The patients affected by vitamin B12-unresponsive methylmalonic acidemia (MMA) on the long run develop chronic renal disease with interstitial nephropathy and progressive renal insufficiency. The mechanism of nephrotoxicity in vitamin B12-unresponsive MMA is not yet known. Chronic hyporeninemic hypoaldosteronism has be... | ['Child, Preschool', 'Female', 'Fumarates', 'Humans', 'Hyperkalemia', 'Hypoaldosteronism', 'Infant', 'Kidney', 'Male', 'Maleates', 'Metabolism, Inborn Errors', 'Vitamin B 12'] | 16,878,438 | [['M01.060.406.448'], ['D02.241.081.337.302'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.396'], ['C19.053.500.480'], ['M01.060.703'], ['A05.810.453'], ['D02.241.081.337.502'], ['C16.320.565', 'C18.452.648'], ['D03.383.129.578.840.437.777', 'D03.633.400.909.437.777', 'D04.345.783.437.777']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Apparent glucose utilization in Walker 256 metastatic brain tumors. | Regional rates of apparent glucose utilization (GU) in metastatic Walker 256 (WL-256) brain tumors produced by the intracarotid injection of WL-256 tumor cells in rats were measured using 14C-deoxyglucose and quantitative autoradiography. Apparent glucose utilization was uniform within individual small and medium size ... | ['Animals', 'Brain Neoplasms', 'Carcinoma 256, Walker', 'Deoxy Sugars', 'Deoxyglucose', 'Female', 'Kinetics', 'Neoplasm Metastasis', 'Rats', 'Rats, Inbred Strains', 'Tritium'] | 4,031,973 | [['B01.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.435.290.210', 'C04.557.450.795.290.210', 'C04.619.045'], ['D09.254'], ['D09.254.229'], ['G01.374.661', 'G02.111.490'], ['C04.697.650', 'C23.550.727.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Plastic reconstruction of the irradiated thoracic wall]. | Chest-wall reconstruction following irradiation requires a surgical approach that addresses the specific healing disorders associated with irradiation: (1) biopsy of any open wound to rule out recurrence or persistence of tumor; (2) aggressive debridement of all necrotic or infected tissue, especially osteonecrosis of ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Chondrosarcoma', 'Female', 'Histiocytoma, Benign Fibrous', 'Humans', 'Male', 'Middle Aged', 'Radiation Injuries', 'Surgical Flaps', 'Thoracic Neoplasms', 'Thorax'] | 9,931,668 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.450.565.280', 'C04.557.450.795.300'], ['C04.557.450.565.590.425.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.81... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lead concentrations in maternal and cord blood in women users of surma eye cosmetics. | A prospective study was undertaken to analyse the lead concentrations in maternal and cord blood of 71 pregnant Arab women at term who used eye cosmetics, particularly "surma". A total of 64 mothers (90%) used eye cosmetics throughout pregnancy, and, of these, 45% used surma. The lead content of the cosmetics available... | ['Birth Weight', 'Cosmetics', 'Female', 'Fetal Blood', 'Humans', 'Lead', 'Maternal-Fetal Exchange', 'Pregnancy', 'Prospective Studies', 'Saudi Arabia'] | 2,471,445 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['D27.720.269', 'J01.516.213'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.435', 'D01.552.544.435'], ['G08.686.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers. | Human neuroendocrine (NE) cancers range from relatively indolent to highly aggressive. In this study, we combine functional genomics with metabolomics to identify features of NE cancers associated with a poor outcome. Analysis of GeneChip datasets of primary prostate tumors, as well as lymph node and liver metastases f... | ['Animals', 'Cell Line, Tumor', 'Chromatography, Liquid', 'Electrophysiology', 'Gene Expression', 'Genomics', 'Humans', 'Imidazoles', 'Mass Spectrometry', 'Mice', 'Mice, Transgenic', 'Neuroendocrine Tumors', 'Oligonucleotide Array Sequence Analysis', 'Prognosis', 'Receptors, GABA', 'Signal Transduction', 'gamma-Aminobu... | 15,998,737 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.181.400'], ['H01.158.344.528', 'H01.158.782.236'], ['G05.297'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['E05.196.566'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.05... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Arthrosis of glenohumeral joint after arthroscopic Bankart repair: a long-term follow-up of 13 years. | HYPOTHESIS: The purpose of the study was to establish radiologic and clinical occurrence of glenohumeral arthrosis after arthroscopic Bankart repair.MATERIALS AND METHODS: Between January 1994 and December 1998, an arthroscopic Bankart repair was performed in 187 patients at our institution. We were able to assess clin... | ['Adolescent', 'Adult', 'Age Distribution', 'Arthroscopy', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Osteoarthritis', 'Range of Motion, Articular', 'Registries', 'Retrospective Studies', 'Risk Assessment', 'Self-Assessment', 'Severity of Illness Index', 'Sex Distrib... | 21,813,296 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], [... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Twin cities health care mergers, acquisitions, and affiliations. Implications for independent physician practices. | "The health care system in Minnesota, especially in the Twin Cities area, is currently undergoing change that can best be characterized as a consolidation of providers into larger and larger groups (multispecialty clinics, hospital/physician mergers, and expanded HMOs and PPOs). These changes are intended to produce ec... | ['Health Facility Merger', 'Humans', 'Managed Care Programs', 'Minnesota', 'Organizational Affiliation', "Physician's Role", 'Private Practice'] | 1,406,532 | [['N02.278.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['N04.452.602'], ['F01.829.316.616.625.600'], ['N04.452.758.745']] | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Pain processing in the human brainstem and spinal cord before, during, and after the application of noxious heat stimuli. | Descending regulation of spinal cord responses to nociceptive signaling has a strong influence on pain perception. Previous studies using functional magnetic resonance imaging (fMRI) have indicated that in addition to reactive responses to nociceptive signals, there is a continuous component to regulation, and that it ... | ['Afferent Pathways', 'Brain Mapping', 'Brain Stem', 'Female', 'Hot Temperature', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Neural Networks, Computer', 'Oxygen', 'Pain', 'Pain Measurement', 'Pain Threshold', 'Regression Analysis', 'Skin', 'Spinal Cord'] | 29,905,656 | [['A08.612.220'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Is radical cystectomy indicated for the treatment of patients with bladder carcinoma N+ M0?]. | UNLABELLED: The following parameters were analyzed in 55 patients with N + M0 bladder carcinoma: 1. Extent of lymph node involvement: A significant difference was observed for those with N1 whose 5 year survival rate is 46%, whereas those with N3, N4 did not survive at two years. 2.TREATMENT: 29 patients underwent cyst... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Transitional Cell', 'Cisplatin', 'Combined Modality Therapy', 'Cyclophosphamide', 'Cystectomy', 'Doxorubicin', 'Evaluation Studies as Topic', 'Female', 'Fluorouracil', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Methotrexate', ... | 2,064,422 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.430'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E04.950.774.150'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism. | AIMS: We evaluated the involvement of cytochrome P450 (CYP) isoforms 2C9 and 2C19 in chlorpropamide 2-hydroxylation in vitro and in chlorpropamide disposition in vivo.METHODS: To identify CYP isoforms(s) that catalyse 2-hydroxylation of chlorpropamide, the incubation studies were conducted using human liver microsomes ... | ['Administration, Oral', 'Adult', 'Aryl Hydrocarbon Hydroxylases', 'Chlorpropamide', 'Cytochrome P-450 CYP2C19', 'Cytochrome P-450 CYP2C9', 'Female', 'Humans', 'Hydroxylation', 'Hypoglycemic Agents', 'Liver', 'Male', 'Microsomes', 'Mixed Function Oxygenases', 'Polymorphism, Genetic'] | 15,842,554 | [['E02.319.267.100'], ['M01.060.116'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['D02.065.950.828.283', 'D02.886.590.795.283'], ['D08.244.453.491.500.700', 'D08.811.682.690.708.170.450.500.700', 'D12.776.422.220.453.491.500.700'], ['D08.244.453.491.500.500', 'D08.811.682.690.708.17... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Contrasting effects of clonidine and 5-hydroxytryptophan on spinal sympathetic pathways. | The effects of clonidine HCI were compared with those of 5-HTP on transmission through two spinal sympathetic pathways, segmental spinal reflex pathways and descending intraspinal excitatory pathways, in unanesthetized spinal cats. Evoked sympathetic discharges were recorded from upper thoracic preganglionic rami. Clon... | ['5-Hydroxytryptophan', 'Animals', 'Cats', 'Clonidine', 'Dose-Response Relationship, Drug', 'Neural Pathways', 'Receptors, Adrenergic', 'Spinal Cord', 'Sympathetic Nervous System'] | 6,977,434 | [['D12.125.072.050.850.479'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D03.383.129.308.436.500'], ['G07.690.773.875', 'G07.690.936.500'], ['A08.612'], ['D12.776.543.750.670.300.300', 'D12.776.543.750.695.150.300', 'D12.776.543.750.720.330.300'], ['A08.186.854'], ['A08.800.050.800']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence and associated risk indicators of retinopathy in a rural Bangladeshi population with and without diabetes. | PURPOSE: To determine the prevalence of retinopathy among people with normal and abnormal glucose metabolism in a remote rural community of Bangladesh, and to identify the associated risk indicators for developing retinopathy in this population.METHODS: A population-based cross-sectional study was conducted through scr... | ['Adult', 'Albuminuria', 'Anthropometry', 'Bangladesh', 'Blood Pressure', 'Creatine', 'Cross-Sectional Studies', 'Diabetes Mellitus', 'Diabetic Retinopathy', 'Female', 'Glucose Tolerance Test', 'Glycated Hemoglobin A', 'Humans', 'Lipids', 'Male', 'Middle Aged', 'Prevalence', 'Risk Factors', 'Rural Population', 'Young A... | 23,865,602 | [['M01.060.116'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['Z01.252.245.131'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.078.370.280', 'D12.125.373'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Balloon catheter use for cervical ripening in women with term pre-labor rupture of membranes: A 5-year cohort study. | INTRODUCTION: To investigate the safety of balloon catheter for cervical ripening in women with term pre-labor rupture of membranes (PROM) and to compare the incidence of maternal and neonatal infections in women with PROM and women with intact membranes undergoing cervical ripening with a balloon catheter.MATERIAL AND... | ['Adult', 'Catheters', 'Cervical Ripening', 'Cohort Studies', 'Female', 'Humans', 'Labor, Induced', 'Pregnancy', 'Retrospective Studies', 'Term Birth'] | 32,242,917 | [['M01.060.116'], ['E07.132'], ['G08.686.784.769.326.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.520.252.968'], ['G08.686.784.769'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Measures of low lung function and the prediction of incident COPD events and acute coronary events. | BACKGROUND: Although reduced lung function is associated with both COPD and coronary events (CE), the pattern of lung function impairment could be different for the two outcomes. We examined different measures of lung function in relation to incident COPD events and CE in a population-based cohort.METHODS: Baseline spi... | ['Acute Coronary Syndrome', 'Age Factors', 'Cohort Studies', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Pulmonary Disease, Chronic Obstructive', 'Respiratory Function Tests', 'Risk Management', 'Time Factors'] | 30,366,586 | [['C14.280.647.124', 'C14.907.585.124'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'],... | ['Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Self-renewal of embryonic stem cells through culture on nanopattern polydimethylsiloxane substrate. | Embryonic stem (ES) cells can undergo continual proliferation and differentiation into cells of all somatic cell lineages in vitro; they are an unlimited cell source for regenerative medicine. However, techniques for maintaining undifferentiated ES cells are often inefficient and result in heterogeneous cell population... | ['Animals', 'Cell Adhesion', 'Cell Culture Techniques', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Dimethylpolysiloxanes', 'Embryonic Stem Cells', 'Focal Adhesion Protein-Tyrosine Kinases', 'Focal Adhesions', 'Leukemia Inhibitory Factor', 'Mice', 'Nanoparticles', 'Surface Properties'] | 22,541,355 | [['B01.050'], ['G04.022'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['A11.872.700.250'], ['D08.811.913.696.620.682.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Kinetics of cAMP inhibition of DNA synthesis in bovine adrenocortical cells. | cAMP-treated bovine adrenocortical cells are arrested in the G1 phase of the cell cycle. Removal of serum also arrests bovine adrenocortical cells in G1. In the presence of cAMP, serum and fibroblast growth factor stimulate increases in medium cell volume, but DNA synthesis is not initiated. Under these conditions cAMP... | ['8-Bromo Cyclic Adenosine Monophosphate', 'Adrenal Cortex', 'Animals', 'Bucladesine', 'Cattle', 'Cell Cycle', 'Cyclic AMP', 'DNA', 'Fibroblast Growth Factors', 'Kinetics', 'Peptides'] | 6,248,401 | [['D03.633.100.759.646.138.395.225', 'D13.695.462.200.225', 'D13.695.667.138.395.225', 'D13.695.827.068.395.225'], ['A06.300.071.140'], ['B01.050'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['B01.050.150.900.649.313.500.380.271'], ['G04.144'], ['D... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interaction between vaccinia virus and human blood platelets. | The objective of the present study was to characterize the interaction between human platelets and vaccinia virus and to examine possible impairment of platelet functions. The vaccinia virus was selected for our model system because it lacks detectable neuraminidase activity. Platelets were incubated with purified vira... | ['Adsorption', 'Blood Platelets', 'Humans', 'Phosphates', 'Platelet Aggregation', 'Receptors, Virus', 'Serotonin', 'Sialic Acids', 'Sulfhydryl Compounds', 'Vaccinia virus'] | 7,059,666 | [['G01.030', 'G02.020'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['G09.188.370.687', 'G09.188.390.600.640'], ['D12.776.543.750.830'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.05... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Response of Escherichia coli strains carrying plasmid(s) and their plasmidless derivatives to bactericidal activity of human serum and polymorphonuclear leukocytes. | Ten virulence plasmid(s) and antibiotic resistance plasmid(s) carrying Escherichia coli strains isolated from stool of infants with diarrhoea and their plasmidless derivatives were examined for response to bactericidal activity of human serum and intracellular killing of polymorphonuclear leukocytes (PMN). Plasmid(s) c... | ['Blood Bactericidal Activity', 'Escherichia coli', 'Humans', 'Neutrophils', 'Phagocytosis', 'Plasmids', 'Virulence'] | 1,805,497 | [['G09.188.100', 'G12.450.564.204'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.