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[Cardiac effects of GH]. | To investigate cardiac effects of excess and deficiency of growth hormone (GH) we studied twenty acromegalic subjects and eleven adult patients with GH deficiency by means of a non invasive method, the Doppler echocardiography. The results obtained in the group of patients were compared with those of two groups of twen... | ['Acromegaly', 'Adult', 'Cardiomegaly', 'Clonidine', 'Echocardiography, Doppler', 'Female', 'Growth Hormone', 'Growth Hormone-Releasing Hormone', 'Heart Ventricles', 'Humans', 'Hypertension', 'Insulin-Like Growth Factor I', 'Male', 'Middle Aged', 'Pyridostigmine Bromide', 'Stroke Volume', 'Ventricular Function, Left'] | 8,190,051 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['M01.060.116'], ['C14.280.195', 'C23.300.775.250'], ['D03.383.129.308.436.500'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Current concepts on the diagnostic use of MIBG in children. | Metaiodobenzylguanidine (MIBG) was developed 18 yr ago for scintigraphic imaging of the adrenomedullary tumors pheochromocytoma and neuroblastoma. Many studies have shown the usefulness of this agent for the management of patients with neuroblastoma or pheochromocytoma, and the 131I-labeled form was recently approved b... | ['3-Iodobenzylguanidine', 'Adrenal Gland Neoplasms', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Iodine Radioisotopes', 'Neuroblastoma', 'Pheochromocytoma', 'Radiation Dosage', 'Radionuclide Imaging', 'Radiopharmaceuticals'] | 9,544,682 | [['D02.078.370.510', 'D02.455.426.559.389.454.300', 'D02.455.526.581.496.300'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Residues of Salbutamol and Identification of Its Metabolites in Beef Cattle. | Salbutamol, a selective â2-agonist, endangers the safety of animal products because of its illegal use in food animals. In this work, residues of salbutamol and its metabolites were investigated to select appropriate targets and marker residues for monitoring the illegal use of salbutamol. Ten metabolites of salbutamol... | ['Adrenergic beta-2 Receptor Agonists', 'Albuterol', 'Animals', 'Cattle', 'Chromatography, High Pressure Liquid', 'Drug Residues', 'Kidney', 'Liver', 'Male', 'Mass Spectrometry'] | 28,322,048 | [['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.300'], ['N06.850.460.200.250'], ['A05.810.453'], ['A03.620'], ['E05.196.566']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Electrophysiological study of acamprosate effects on frontal cortical neurons in rats]. | The effect of drug for alcoholism treatment acamprosate (campral) on spontaneous electrical activity of frontal cortical neurons was studied in rats. Acamprosate after acute intraperitoneal administration (600 mg/kg) and microiontophoretic application reduced the frequency of spike activity in about 30 % of cells studi... | ['Acamprosate', 'Action Potentials', 'Alcohol Deterrents', 'Animals', 'Ethanol', 'Frontal Lobe', 'Injections, Intraperitoneal', 'Injections, Intraventricular', 'Iontophoresis', 'Male', 'Microelectrodes', 'Neurons', 'Rats', 'Rats, Wistar', 'Taurine'] | 24,003,480 | [['D02.455.326.146.100.850.438', 'D02.886.645.600.055.850.400'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D27.505.954.427.020'], ['B01.050'], ['D02.033.375'], ['A08.186.211.200.885.287.500.270'], ['E02.319.267.530.490'], ['E02.319.267.530.550'], ['E02.319.267.650', 'E05.301.300.575'], ['E07.305.250.500'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An outlier pool for Medicare HMO payments. | Medicare pays "at-risk" health maintenance organizations a prospective capitation amount that is established by the adjusted average per capita cost (AAPCC) formula for estimating the amount enrollees would have cost had they remained in the fee-for-service sector. Because the AAPCC accounts for a very small percentage... | ['Capitation Fee', 'Health Maintenance Organizations', 'Insurance Pools', 'Medicare', 'Outliers, DRG', 'Prospective Payment System', 'Rate Setting and Review', 'Risk', 'United States'] | 10,124,439 | [['N03.219.442.090'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['N03.219.521.576.570'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['N03.219.521.710.305.200.080.550'], ['N03.219.521.710.305.200'], ['N03.219.442.800'... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Evidence of preservation injury to bile ducts by bile salts in the pig and its prevention by infusions of hydrophilic bile salts. | Preservation injury to bile ducts is a serious problem in liver transplantation, especially when preservation exceeds 12 hours. The authors hypothesized that the injury was caused by contact of bile ducts with bile salts during cold preservation and might be preventable by infusion of more hydrophilic bile salts. Swine... | ['Adenosine', 'Allopurinol', 'Animals', 'Bile Acids and Salts', 'Bile Ducts', 'Female', 'Glutathione', 'Insulin', 'Organ Preservation', 'Organ Preservation Solutions', 'Raffinose', 'Swine', 'Swine, Miniature'] | 7,705,788 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.160'], ['B01.050'], ['D04.210.500.105'], ['A03.159.183'], ['D12.644.456.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['E02.792.833.660', 'E05.760.833.660'], ['D26.776.675'], ['D09.698.629.802.700'], ['B01.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of alcohol consumption on the progression of hepatitis C virus infection and risk of hepatocellular carcinoma in Japanese patients. | Chronic hepatitis C virus (HCV) infection is associated with a spectrum of liver diseases and a proportion of chronic cases progress through cirrhosis to hepatocellular carcinoma (HCC). The viral and host factors that are important in the clinical and histological progression of HCV infection are unclear. We investigat... | ['Adult', 'Aged', 'Alcohol Drinking', 'Alcoholism', 'Carcinoma, Hepatocellular', 'Disease Progression', 'Female', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Japan', 'Liver Cirrhosis', 'Liver Diseases, Alcoholic', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Retrospective Studies', 'Statistics, Nonparametric'] | 10,869,250 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C23.550.291.656'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. | OBJECTIVES: To evaluate the performance of first-trimester screening for trisomy 21 by a combination of maternal age, fetal nuchal translucency (NT) and maternal serum free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A). In addition, the potential impact of a new individ... | ['Adolescent', 'Adult', 'Chorionic Gonadotropin, beta Subunit, Human', 'Down Syndrome', 'Female', 'Humans', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnancy-Associated Plasma Protein-A', 'Prenatal Diagnosis', 'Risk Assessment', 'Ultrasonography, Prenatal'] | 15,736,186 | [['M01.060.057'], ['M01.060.116'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacokinetics of intravenous diltiazem and five of its metabolites in patients with chronic renal failure and in healthy volunteers. | The pharmacokinetics of diltiazem were studied in seven patients with chronic renal failure (CRF) not requiring dialysis and in three healthy volunteers after a rapid i.v. infusion of 20 mg. Mean plasma concentrations at the end of infusion were 3.15 times higher in patients with CRF than in healthy volunteers. From 0.... | ['Adult', 'Diltiazem', 'Female', 'Humans', 'Injections, Intravenous', 'Kidney Failure, Chronic', 'Male', 'Middle Aged'] | 2,031,991 | [['M01.060.116'], ['D03.633.100.079.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The effect of ligustrazine on cells proliferation in cortex and striatum after focal cerebral ischemia in adult rats]. | OBJECTIVE: To explore the effect of Ligustrazine on cells proliferation in cortex and striatum after focal cerebral ischemia in adult rats.METHODS: Focal cerebral ischemia was induced by left middle cerebral artery occlusion (MCAO) with suture method. Two hours later, injection of Ligustrazine (80 mg/kg, 1 time/d) was ... | ['Animals', 'Apiaceae', 'Brain Ischemia', 'Cell Count', 'Cell Proliferation', 'Cerebral Cortex', 'Corpus Striatum', 'Drugs, Chinese Herbal', 'Infarction, Middle Cerebral Artery', 'Male', 'Plants, Medicinal', 'Pyrazines', 'Rats', 'Rats, Sprague-Dawley'] | 17,228,661 | [['B01.050'], ['B01.650.940.800.575.912.250.075'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.161.750', 'G07.345.249.410.750'], ['A08.186.211.200.885.287.500'], ['A08.186.211.200.885.287.249.487'], ['D20.215.784.500.350', 'D26.335'], ['C10.228... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a small-scale bioreactor method to monitor the molecular diversity and environmental impacts of bacterial biofilm communities from an acid mine drainage impacted creek. | Shamokin Creek is a tributary of the Susquehanna River in central Pennsylvania that is heavily impacted by the acid mine drainage (AMD) caused by the oxidation of pyrite from the region's extensive anthracite coal mining industry. Recent studies have begun to characterize the microbial communities present in this and o... | ['Biofilms', 'Bioreactors', 'Coal Mining', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Hydrogen-Ion Concentration', 'Metals', 'Models, Biological', 'Oxidation-Reduction', 'Pennsylvania', 'Polymorphism, Restriction Fragment Length', 'RNA, Ribosomal, 16S', 'Rivers', 'Sulfur', 'Water', 'Water Pollution, Chemical'... | 21,821,067 | [['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['J01.576.655.875.500.500'], ['B03.440'], ['B03.510'], ['G02.300'], ['D01.552'], ['E05.599.395'], ['G02.700', 'G03.295.531'], ['Z01.107.567.875.075.550', 'Z01.107.567.875.350.550', 'Z01.107.567.875.500.550'], ['G05.365.795.595'], ['D13.444.735.686.670'], ['G01.31... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Elevated â-Carotene Synthesis by the Engineered Rhodobacter sphaeroides | â-Carotene is a precursor of vitamin A and a dietary supplement for its antioxidant property. Producing â-carotene by microbial fermentation has attracted much attention owing to consumers' preference for the natural product. In this study, an engineered photosynthetic Rhodobacter sphaeroides producing â-carotene was c... | ['Bacterial Proteins', 'Fermentation', 'Intramolecular Lyases', 'Light', 'Metabolic Engineering', 'Promoter Regions, Genetic', 'Rhodobacter sphaeroides', 'beta Carotene'] | 31,368,704 | [['D12.776.097'], ['G02.111.158.249', 'G03.191.249'], ['D08.811.399.430'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.393.420.526', 'E05.481.500.311.249', 'J01.293.069.249.249'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['B03.440.623... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Post-transfusion alloimmunization in patients with sickle cell disease. | The transfusion histories over a 33-month period of 50 patients with sickle cell disease were reviewed to determine the frequency of alloimmunization to red cell antigens following transfusion in these patients. There were 30 females and 20 males, aged 19--49 years. Eighteen (36%) were immunized of which thirteen were ... | ['Adult', 'Anemia, Sickle Cell', 'Duffy Blood-Group System', 'Female', 'Humans', 'Isoantibodies', 'Kell Blood-Group System', 'Kidd Blood-Group System', 'Lewis Blood Group Antigens', 'MNSs Blood-Group System', 'Male', 'Middle Aged', 'Pregnancy', 'Rh-Hr Blood-Group System', 'Transfusion Reaction'] | 104,621 | [['M01.060.116'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['D23.050.301.290.301', 'D23.050.705.230.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.664', 'D12.776.124.790.651.114.664', 'D12.776.377.715.548.114.664'], ['D23.050.301.290.533', ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Robotic versus laparoscopic radical hysterectomy in cervical cancer patients: a matched-case comparative study. | OBJECTIVE: This study aimed to compare initial surgical outcomes and complication rates of patients with early-stage cervical cancer who underwent robotic radical hysterectomy (RRH) and conventional laparoscopic radical hysterectomy (LRH).METHODS: Patients diagnosed with invasive cervical cancer (International Federati... | ['Adenocarcinoma', 'Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Case-Control Studies', 'Female', 'Humans', 'Hysterectomy', 'Laparoscopy', 'Length of Stay', 'Middle Aged', 'Postoperative Complications', 'Robotic Surgical Procedures', 'Uterine Cervical Neoplasms'] | 25,207,462 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E02.760.400.4... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Mast cell leukemia with rapidly progressing portal hypertension. | Reported herein is an autopsy case of mast cell leukemia, a rare form of systemic mastocytosis, complicated with portal hypertension. A 52-year-old woman presented with urticaria-like skin symptoms, anemia, and thrombocytopenia. Atypical mast cells (CD2+, CD25+, CD117+) with toluidine blue metachromasia were found in t... | ['Appendicitis', 'Fatal Outcome', 'Female', 'Glomerulonephritis, IGA', 'Humans', 'Hypertension, Portal', 'Leiomyoma', 'Leukemia, Mast-Cell', 'Middle Aged', 'Ovarian Cysts', 'Uterine Neoplasms'] | 19,883,434 | [['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C12.777.419.570.363.608', 'C13.351.968.419.570.363.608', 'C20.111.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['C04... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Significance of rapid turnover proteins in protein-losing gastroenteropathy. | BACKGROUND/AIMS: We investigated the significance of rapid turnover proteins (retinal-binding protein, pre-albumin and transferrin) in protein-losing gastroenteropathy.METHODOLOGY: We evaluated the levels of these proteins in 12 patients with protein-losing gastroenteropathy.RESULTS: The protein-losing gastroenteropath... | ['Adolescent', 'Adult', 'Aged', 'Blood Proteins', 'Carrier Proteins', 'Diagnosis, Differential', 'Female', 'Humans', 'Immunoglobulin G', 'Male', 'Middle Aged', 'Prealbumin', 'Protein-Losing Enteropathies', 'Reference Values', 'Serum Albumin', 'Transferrin'] | 14,696,443 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124'], ['D12.776.157'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['M01.060.116.630'], ['D12.776.034.841.450', 'D12.776.124.727... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genomic analysis of Staphylococcus capitis isolated from blood cultures in neonates at a neonatal intensive care unit in Sweden. | Emergence of a genetically distinct, multidrug-resistant Staphylococcus capitis clone (NRCS-A) present in neonatal intensive care units has recently been extensively reported. The aims of the present study were to investigate which clones of S. capitis isolated from blood in a Swedish neonatal intensive care unit (NICU... | ['Anti-Bacterial Agents', 'Bacteremia', 'Drug Resistance, Multiple, Bacterial', 'Genes, Bacterial', 'Genome, Bacterial', 'Humans', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Microbial Sensitivity Tests', 'Phylogeny', 'Polymorphism, Single Nucleotide', 'Staphylococcal Infections', 'Staphylococcus capitis', 'S... | 31,396,832 | [['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.358.207'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Effect of hydrogen peroxide disinfection during incubation of chicken eggs on microbial levels and productivity. | Hatchery sanitation has a significant impact on chick quality. The proper use of disinfectants is essential. Aerosol bacterial counts, egg moisture loss, hatchability, chick quality, and broiler productivity were measured in eggs exposed to hydrogen peroxide fogging and compared with eggs not exposed to disinfectant du... | ['Aerosols', 'Air Pollution, Indoor', 'Animal Husbandry', 'Animals', 'Animals, Newborn', 'Anti-Infective Agents, Local', 'Chickens', 'Disinfection', 'Eggs', 'Female', 'Food Handling', 'Housing, Animal', 'Hydrogen Peroxide', 'Male', 'Staphylococcus aureus', 'Yolk Sac'] | 10,396,635 | [['D20.280.055', 'D26.255.165.055'], ['N06.850.460.100.080'], ['J01.040.090'], ['B01.050'], ['B01.050.050.282'], ['D27.505.954.122.187'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['N06.850.780.200.450.850.375'], ['G07.203.300.470', 'J02.500.470'], ['J01.576.423.200'], ['J03.340.250', 'N06.230.150... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Cell-free DNA induced apoptosis of granulosa cells by oxidative stress. | BACKGROUND: Cell-free DNA is a DNA fragment that is produced by cell apoptosis which can affect the micro-environment of cell apoptosis. The levels of Cell-free DNA have been associated with successful rate of in vitro fertilization-embryo transfer (IVF-ET) and embryonic development. Our aim is to determine the relatio... | ['Adult', 'Apoptosis', 'Cell-Free Nucleic Acids', 'Fas Ligand Protein', 'Female', 'Granulosa Cells', 'Humans', 'Oxidative Stress', 'Pregnancy', 'Signal Transduction', 'fas Receptor'] | 27,884,753 | [['M01.060.116'], ['G04.146.954.035'], ['D13.444.154'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.374.750.249', 'D12.776.543.550.312', 'D23.529.374.750.249'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Strengthening children's oral health: views from the field. | Low-income children and adolescents continue to bear a heavy burden of untreated pain and complications from dental disease. To explore why proposals to remediate this problem have not gained traction, the authors interviewed experts involved in efforts to improve the oral health status of low-income and minority child... | ['Child', 'Delivery of Health Care', 'Health Services Accessibility', 'Humans', 'Interviews as Topic', 'Oral Health', 'Poverty Areas', 'United States'] | 22,068,412 | [['M01.060.406'], ['N04.590.374', 'N05.300'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N01.400.535'], ['I01.880.853.996.535.550', 'N01.824.600.550'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Expression of class I histocompatibility antigens on human T-B lymphoblast hybrids. | Expression of class I histocompatibility antigens (HLA-A and B) on hybrids of human T and B lymphoblastoid cell lines (LCL) was examined. The T-LCL CEM expressed low levels of HLA-A and B antigens. CEMR and CEMR .3, two 8-azaguanine- and ouabain-resistant sublines of CEM used for fusion, expressed no detectable HLA-B a... | ['Antibodies, Monoclonal', 'B-Lymphocytes', 'Cell Line', 'Flow Cytometry', 'HLA Antigens', 'HLA-A Antigens', 'HLA-B Antigens', 'Humans', 'Hybrid Cells', 'T-Lymphocytes'] | 6,609,440 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.251.210'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of relaxin on parturition and frequency of live births in pigs. | Gilts on Day 105 of gestation were sham ovariectomized (Group C, N = 5); ovariectomized and given i.m. injections of 100 mg progesterone twice daily from Day 105 to 112 (Group OP, N = 5); or ovariectomized and given progesterone and i.m. injections of 1 mg highly purified porcine relaxin 4 times/day from Day 105 until ... | ['Animals', 'Castration', 'Female', 'Fetal Death', 'Labor, Obstetric', 'Pregnancy', 'Progesterone', 'Relaxin', 'Swine'] | 7,120,196 | [['B01.050'], ['E04.270.282', 'E04.950.165'], ['C13.703.223', 'C23.550.260.585'], ['G08.686.784.769.326'], ['G08.686.784.769'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['D06.472.334.734.769', 'D06.472.699.715', 'D12.644.548.762'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deep and superficial abdominal muscle activation during trunk stabilization exercises with and without instruction to hollow. | The deepest muscle of the human ventro-lateral abdominal wall, the Transversus Abdominis (TrA), has been ascribed a specific role in spine stabilization, which has motivated special core stability exercises and hollowing instruction to specifically involve this muscle. The purpose here was to evaluate the levels of act... | ['Abdominal Muscles', 'Adult', 'Analysis of Variance', 'Electromyography', 'Exercise Therapy', 'Female', 'Humans', 'Low Back Pain', 'Muscle Contraction', 'Posture', 'Ultrasonography, Interventional'] | 20,570,549 | [['A02.633.567.050'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.405.255', 'E01.370.530.255'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['G11.427.494'], ['G11.427.695'],... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Case report. Spontaneous cholecystocolic fistula and locoregional liver tumour ablation: a cautionary tale. | A liver abscess is a feared and potentially fatal complication following transarterial chemoembolisation (TACE) and radiofrequency ablation (RFA) of liver tumours. Iatrogenic bilio-enteric communications, such as bilio-enteric anastomosis, sphincterotomy and biliary stents, are considered major risk factors and are due... | ['Aged', 'Biliary Fistula', 'Catheter Ablation', 'Chemoembolization, Therapeutic', 'Colonic Neoplasms', 'Gallbladder Diseases', 'Humans', 'Liver Abscess', 'Liver Neoplasms', 'Male', 'Tomography, X-Ray Computed'] | 22,101,592 | [['M01.060.116.100'], ['C06.267.150', 'C23.300.575.185.150'], ['E02.808.750.500', 'E04.014.760.500'], ['E02.520.360.150', 'E02.926.500.150'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C06.130.564'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Effect of COVID-19 on Orthopedic Practices and Surgeons in Louisiana. | This study was performed to analyze the effect that coronavirus 2019 (COVID-19) has had on orthopedic surgeons' practices, their patients, and orthopedic surgeons themselves through a survey distributed to members of the Louisiana Orthopaedic Association (LOA). An anonymous 22-question online survey was created and dis... | ['Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Elective Surgical Procedures', 'Facilities and Services Utilization', 'Female', 'Health Care Surveys', 'Hospital Administration', 'Humans', 'Income', 'Louisiana', 'Male', 'Orthopedic Procedures', 'Orthopedic Surgeons', 'Pandemics', 'Pneumonia, Viral', "Practice... | 33,211,903 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['E04.249'], ['E05.318.740.388', 'H01.548.832.625', 'N04.452.289', 'N05.715.360.750.344', 'N06.850.520.830... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Loss of smad4 in Sertoli and Leydig cells leads to testicular dysgenesis and hemorrhagic tumor formation in mice. | As the central component of canonical TGFbeta superfamily signaling, SMAD4 is a critical regulator of organ development, patterning, tumorigenesis, and many other biological processes. Because numerous TGFbeta superfamily ligands are expressed in developing testes, there may exist specific requirements for SMAD4 in ind... | ['Adenoma', 'Aging', 'Animals', 'Gonadal Dysgenesis', 'Hemorrhage', 'Immunohistochemistry', 'Leydig Cells', 'Male', 'Mice', 'Mice, Knockout', 'Organ Size', 'Seminiferous Tubules', 'Sertoli Cells', 'Smad4 Protein', 'Testicular Neoplasms', 'Testis'] | 24,501,173 | [['C04.557.470.035'], ['G07.345.124'], ['B01.050'], ['C12.706.316.309', 'C13.351.875.253.309', 'C16.131.939.316.309', 'C19.391.119.309'], ['C23.550.414'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Delayed recurrence of acute retinal necrosis (ARN): A case series. | PURPOSE: To report five cases of acute retinal necrosis (ARN) that reactivated in the same eye or presented in the contralateral eye between two and nineteen years after the initial episode of acute retinal necrosis.CASES: Five patients with a previous history of ARN developed recurrent ARN infection following a length... | ['Adolescent', 'Adult', 'Antiviral Agents', 'Female', 'Humans', 'Male', 'Middle Aged', 'Premedication', 'Recurrence', 'Retinal Necrosis Syndrome, Acute', 'Simplexvirus', 'Virus Latency'] | 27,179,886 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.319.703'], ['C23.550.291.937'], ['C11.768.773.674'], ['B04.280.382.100.750'], ['G06.920.900']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Contribution of copper ion resistance to survival of Escherichia coli on metallic copper surfaces. | Bacterial contamination of touch surfaces poses a serious threat for public health. The use of bactericidal surface materials, such as copper and its alloys, might constitute a way to aid the use of antibiotics and disinfectants, thus minimizing the risk of emergence and spread of multiresistant germs. The survival of ... | ['Cations', 'Copper', 'Escherichia coli', 'Oxidation-Reduction', 'Reactive Oxygen Species', 'Survival Analysis'] | 18,156,321 | [['D01.248.497.300'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.700', 'G03.295.531'], ['D01.339.431', 'D01.650.775'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Screening for effects of phytochemical variability on cytoplasmic protein synthesis pattern of crop plants. | Crop plants have to cope with phytochemical variability along with other environmental stresses. Allelochemicals affect several cellular processes. We tested the effect of toxic aqueous leachates from Sicyos deppei, Acacia sedillense, Sebastiania adenophora, and Lantana camara on the radicle growth and cytoplasmic prot... | ['Cucurbita', 'Cytoplasm', 'Lycopersicon esculentum', 'Molecular Weight', 'Plant Extracts', 'Plant Roots', 'Plants', 'Protein Biosynthesis', 'Zea mays'] | 11,944,837 | [['B01.650.940.800.575.912.250.300.222'], ['A11.284.430.214'], ['B01.650.940.800.575.912.250.908.500.322'], ['G02.494'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['B01.650'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['B01.650.940.800.575.912.250.822.966']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Earlier onset of diabesity-Induced adverse cardiac remodeling in female compared to male mice. | OBJECTIVE: Emerging evidence suggests female type 2 diabetes (T2DM) patients may fare worse than males with respect to cardiovascular complications. Hence the impact of sex on relative progression of left ventricular (LV) remodeling in obese db/db mice was characterized.METHODS: The changes in parameters of LV hypertro... | ['Animals', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Female', 'Fibrosis', 'Heart', 'Hypertrophy, Left Ventricular', 'Male', 'Mice', 'Mice, Obese', 'Models, Animal', 'Myocytes, Cardiac', 'Natriuretic Peptide, Brain', 'Oxidative Stress', 'Plasminogen Activator Inhibitor 1', 'Reactive Oxygen Species', 'Sex Factors',... | 25,959,739 | [['B01.050'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.550.355'], ['A07.541'], ['C14.280.195.400', 'C23.300.775.250.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.530'], ['E05.598'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Outward K+ current in epithelial cells isolated from intermediate portion of endolymphatic sac of guinea pigs. | Ion currents in epithelial cells isolated from the intermediate portion of endolymphatic sac (ES) in guinea pigs were investigated with the use of the whole cell patch-clamp technique. Depolarizing voltage steps from a holding potential of -60 mV induced a time- and voltage-dependent outward current, which is comparabl... | ['Animals', 'Cells, Cultured', 'Epithelium', 'Female', 'Guinea Pigs', 'Kinetics', 'Lymphatic System', 'Male', 'Membrane Potentials', 'Patch-Clamp Techniques', 'Potassium', 'Potassium Channels', 'Time Factors'] | 8,944,662 | [['B01.050'], ['A11.251'], ['A10.272'], ['B01.050.150.900.649.313.992.550'], ['G01.374.661', 'G02.111.490'], ['A15.382.520'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E05.200.500.905', 'E05.242.800'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D12.776.157.530.400.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Esophageal atresia with distal tracheo-esophageal fistula. Evolution of the treatment in the period of 1955-2000 at the Anna Meyer Children's Hospital of Florence]. | BACKGROUND: Over the past decades the esophageal atresia (EA) has represented the greatest challenging malformation encountered by the pediatric surgeon. Since then, there have been considerable advancements in the treatment of EA. In this paper the experience at the "Anna Meyer Children's Hospital of Florence" in rega... | ['Esophageal Atresia', 'Esophageal Fistula', 'Female', 'Fistula', 'Humans', 'Infant, Newborn', 'Male', 'Tracheal Diseases', 'Treatment Outcome'] | 11,981,527 | [['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['C06.267.250', 'C06.405.117.367', 'C23.300.575.185.250'], ['C23.300.575'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C08.907'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Construction of pSPI12-cured Salmonella enterica serovar Pullorum and identification of IpaJ as an immune response modulator. | In Salmonella, plasmids participate in many pathways involved in virulence, metabolism, and antibiotic resistance. To investigate the function of the ipaJ gene in a multi-copy plasmid pSPI12 prevalent in Salmonella enterica serovar Pullorum (S. Pullorum), we established a method to eliminate the plasmid and constructed... | ['Animals', 'Antigens, Bacterial', 'Bacterial Proteins', 'Chickens', 'Cytokines', 'Genetic Vectors', 'Immunologic Factors', 'Macrophages', 'Plasmids', 'Poultry Diseases', 'Salmonella Infections, Animal', 'Salmonella enterica', 'Serogroup', 'Specific Pathogen-Free Organisms', 'Spleen', 'Virulence'] | 29,712,441 | [['B01.050'], ['D23.050.161'], ['D12.776.097'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.360.337'], ['D27.505.696.477'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['G05.360.600'], ['C22.131.728... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of retinol, antioxidant vitamins and homocysteine in skin puncture blood. | For determination of the vitamin status via mass screening, simple and rapid methods are required. Additionally, blood samples should be obtained using simple and low invasive sampling techniques. To fulfill this existing methods have been modified to analyze retinol, tocopherols, beta-carotene, vitamin C and homocyste... | ['Antioxidants', 'Calibration', 'Capillaries', 'Chromatography, High Pressure Liquid', 'Homocysteine', 'Humans', 'Mass Screening', 'Nutritional Status', 'Skin', 'Vitamin A'] | 10,526,774 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.978.155'], ['A07.015.461.165'], ['E05.196.181.400.300'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.85... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multi-unit relations among neural, self-report, and behavioral correlates of emotion regulation in comorbid depression and obesity. | Depression is a leading cause of disability and is commonly comorbid with obesity. Emotion regulation is impaired in both depression and obesity. In this study, we aimed to explicate multi-unit relations among brain connectivity, behavior, and self-reported trait measures related to emotion regulation in a comorbid dep... | ['Adult', 'Aged', 'Comorbidity', 'Connectome', 'Depression', 'Emotions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Reaction Time', 'Self Report', 'White Matter', 'Young Adult'] | 30,232,351 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.370.350.578.875.500.249', 'E01.370.376.537.625.500.249', 'E05.629.875.500.500'], ['F01.145.126.350'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.37... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tear glucose dynamics in diabetes mellitus. | This study compares tear glucose dynamic differences between 121 diabetic and nondiabetic subjects after the administration of a carbohydrate load. A quantitative chromatographic analysis of tear glucose was used and the values correlated to blood glucose values. Diabetic and nondiabetic tear glucose mean values were 0... | ['Blood Glucose', 'Diabetes Mellitus', 'Glucose', 'Humans', 'Monitoring, Ambulatory', 'Prospective Studies', 'Tears'] | 17,114,114 | [['D09.947.875.359.448.500'], ['C18.452.394.750', 'C19.246'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['A12.200.882']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endoscopic laser medial arytenoidectomy for treatment of bilateral vocal fold paralysis. | Endoscopic laser medial arytenoidectomy for bilateral vocal fold paralysis has the advantage of preserving the structure and the position of the vocal fold, contrary to a transverse cordotomy or total arytenoidectomy. Our objective was to evaluate the functional results of this procedure. This is a prospective non-rand... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Arytenoid Cartilage', 'Cohort Studies', 'Female', 'Humans', 'Laryngoscopy', 'Laser Therapy', 'Lasers, Gas', 'Male', 'Middle Aged', 'Prospective Studies', 'Speech Acoustics', 'Spirometry', 'Treatment Outcome', 'Vocal Cord Paralysis', 'Voice Quality', 'Young Adult'] | 23,483,191 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.165.257.625.083', 'A02.165.407.500.083', 'A04.329.591.085'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.460', 'E01.370.388.250.525', '... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of the catalase of the n-alkane-utilizing yeast Candida tropicalis functionally expressed in Saccharomyces cerevisiae. | Candida tropicalis catalase (CTC) genomic DNA was recombined on a plasmid with the galactose-inducible GAL7 promoter and expressed highly as a heme protein in Saccharomyces cerevisiae as host. The percentage of recombinant CTC (rCTC) in total extractable protein amounted to at least 25%. The rCTC was purified and chara... | ['Base Sequence', 'Biotechnology', 'Candida', 'Catalase', 'DNA, Fungal', 'Escherichia coli', 'Gene Expression', 'Genes, Fungal', 'Molecular Sequence Data', 'Plasmids', 'Saccharomyces cerevisiae'] | 7,764,426 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.158.550', 'J01.897.120'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['D08.811.682.732.332'], ['D13.444.308.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Color Doppler sonographic findings in penile fracture. | We performed color Doppler sonographic examination on 4 patients, 3 of whom had preliminary diagnoses of penile fracture and 1 of whom had undergone an operation due to penile fracture a year previously. Color Doppler sonography helped evaluate the relationships between the hematoma and the vascular structures and aide... | ['Adult', 'Hematoma', 'Humans', 'Male', 'Penis', 'Rupture', 'Sensitivity and Specificity', 'Ultrasonography, Doppler, Color'] | 15,690,447 | [['M01.060.116'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.444.492'], ['C26.761'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['E01.370.350.850.850.850.850']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prognostic value of LAT-1 status in solid cancer: A systematic review and meta-analysis. | BACKGROUND: The expression of the L-type amino acid transporter 1 (LAT1) plays a significant role in tumor progression. However, it remains unclear whether high LAT1 expression correlates with poor prognosis of solid tumor patients. Here, we conducted a meta-analysis to assess the potential of LAT1 in predicting the pr... | ['Biliary Tract Neoplasms', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Humans', 'Large Neutral Amino Acid-Transporter 1', 'Lung Neoplasms', 'Neoplasms', 'Pancreatic Neoplasms', 'Prognosis', 'Survival Analysis'] | 32,469,987 | [['C04.588.274.120', 'C06.130.320', 'C06.301.120'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.200.500.500.500.300.500', 'D12.776.157.530.937.313.500.625.500', 'D12.776.543.585.200.500.500.500... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of murine strain on metabolic pathways of glucose production after brief or prolonged fasting. | Background strain is known to influence the way a genetic manipulation affects mouse phenotypes. Despite data that demonstrate variations in the primary phenotype of basic inbred strains of mice, there is limited data available about specific metabolic fluxes in vivo that may be responsible for the differences in strai... | ['Adaptation, Physiological', 'Animals', 'Blood Glucose', 'Fasting', 'Glucose', 'Metabolic Clearance Rate', 'Mice', 'Mice, Inbred Strains', 'Signal Transduction', 'Species Specificity', 'Time Factors'] | 15,797,985 | [['G07.025', 'G16.012.500'], ['B01.050'], ['D09.947.875.359.448.500'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.947.875.359.448'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning of a cDNA encoding ovine keratinocyte growth factor. | A cDNA encoding the ovine keratinocyte growth factor (KGF) has been cloned. A 622-bp cDNA, containing the entire protein coding region, was amplified from an ovine adenocarcinoma fibroblast cell line. The cDNA was found to share 95% nucleotide identity with dog KGF, 94% identity with human KGF, 90% identity with mouse ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'DNA, Complementary', 'Dogs', 'Fibroblast Growth Factor 10', 'Fibroblast Growth Factor 7', 'Fibroblast Growth Factors', 'Growth Substances', 'Humans', 'Mice', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Rats', 'Sequence Analysis, DNA... | 10,520,741 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.150.900.649.313.750.250.216.200'], ['D12.644.276.624.200', 'D12.776.467.624.200', 'D23.529.624.20... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phase I clinical trial of nasopharyngeal radiotherapy and concurrent celecoxib for patients with locoregionally advanced nasopharyngeal carcinoma. | We evaluated the incidence of acute toxicity of concurrent cyclooxygenase-2 inhibitor (celecoxib) plus radiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma (NPC). Thirty-four patients received an accumulated radiation dose of 72-76Gy in 36-38 fractions to the primary lesion and 60Gy in 30 frac... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Celecoxib', 'Combined Modality Therapy', 'Cyclooxygenase 2 Inhibitors', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasopharyngeal Neoplasms', 'Neoplasm Recurrence, Local', 'Pyrazoles', 'Radiation Dosage', 'Sulfonamides', 'Treatment Outcome'] | 21,708,478 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['E02.186'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['E01.789.800.190',... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preliminary testing of GaN-based dosimeters for electron beam radiotherapy. | The response of an implantable in vivo dosimetric system based on gallium nitride radioluminescence was investigated for electron beam radiotherapy using ELEKTA SLi and VARIAN Clinac 2100 CD Linear Accelerators. A bi-channel method has been implemented for fibre background rejection. The percentage depth dose (PDD) pro... | ['Algorithms', 'Electrons', 'Gallium', 'Humans', 'Ions', 'Luminescence', 'Particle Accelerators', 'Phantoms, Imaging', 'Polymethyl Methacrylate', 'Radiometry', 'Radiotherapy', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Reproducibility of Results', 'Software'] | 25,813,482 | [['G17.035', 'L01.224.050'], ['G01.249.335', 'G01.358.500.750'], ['D01.268.556.289', 'D01.552.544.289'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E07.710.680'], ['E07.671'], ['D02.241.081.069.800.550... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Trans mono- and polyunsaturated fatty acids in human milk. | OBJECTIVE: The aim of the present study was to identify the trans isomers of C18 fatty acids in some human milk samples.SUBJECTS: Ten human milk samples from French women were collected in a local milk bank in order to assess their trans mono and polyunsaturated fatty acids (PUFA) content.INTERVENTION: The fatty acid p... | ['Adult', 'Chromatography, High Pressure Liquid', 'Fatty Acids, Monounsaturated', 'Fatty Acids, Unsaturated', 'Female', 'Humans', 'Lactation', 'Milk, Human', 'Stereoisomerism'] | 7,588,503 | [['M01.060.116'], ['E05.196.181.400.300'], ['D10.251.355.325'], ['D10.251.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300.350.525.500', 'J02.200.700.500', 'J02.500.350.525.500'], ['G02.607.445.682']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium. | Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma, a cancer of which the incidence has been increasing at an alarming rate in Western countries. p16(INK4a) lesions occur frequently in esophageal adenocarcinomas but their role in neoplastic progression is not well understood. We detected ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aneuploidy', 'Barrett Esophagus', 'Biopsy', 'Chromosomes, Human, Pair 9', 'Clone Cells', 'CpG Islands', 'Cyclin-Dependent Kinase Inhibitor p16', 'DNA Methylation', 'Epithelial Cells', 'Esophageal Neoplasms', 'Humans', 'Loss of Heterozygosity', 'Metaphase', 'Middle Aged', 'Mutatio... | 11,719,461 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C04.834.154', 'C06.405.117.102'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A11.284.187.520.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chronic kidney disease on hemodialysis is associated with decreased serum PCSK9 levels. | OBJECTIVES: Serum low density lipoprotein-cholesterol (LDL-C) correlates positively with serum PCSK9 in the general population, consistent with PCSK9 being a determinant of LDL-C levels. Patients with chronic kidney disease (CKD) on hemodialysis (HD) have lower total cholesterol (TC) and LDL-C compared to the general p... | ['Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Male', 'Middle Aged', 'Proprotein Convertase 9', 'Proprotein Convertases', 'Renal Dialysis', 'Renal Insufficiency, Chronic', 'Serine Endopeptidases'] | 24,529,132 | [['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Determination of nanograms of proteins based on the amplified resonance light scattering signals of Tichromine. | A new high-sensitivity detection of protein assay at the nanogram level is developed based on the amplified resonance light scattering signals (RLS) of Tichromine (TCM). In Walpole (NaAc-HCl) buffer (pH 4.05), TCM reacts with proteins to form large particles, which results in remarkable enhanced RLS signals characteriz... | ['Animals', 'Biological Assay', 'Buffers', 'Cattle', 'Fluorescent Dyes', 'Humans', 'Hydrogen-Ion Concentration', 'Imines', 'Molecular Structure', 'Naphthalenes', 'Proteins', 'Scattering, Radiation', 'Serum Albumin'] | 20,071,217 | [['B01.050'], ['E05.091'], ['D27.720.470.280'], ['B01.050.150.900.649.313.500.380.271'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D02.491'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.847.638', 'D04.615.638'], ['D12.776'], ['E05.196.822', 'G01.86... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rate and Temporal Coding Mechanisms in the Anterior Cingulate Cortex for Pain Anticipation. | Pain is a complex sensory and affective experience. Through its anticipation, animals can learn to avoid pain. Much is known about passive avoidance during a painful event; however, less is known about active pain avoidance. The anterior cingulate cortex (ACC) is a critical hub for affective pain processing. However, t... | ['Action Potentials', 'Animals', 'Avoidance Learning', 'Conditioning, Classical', 'Electrodes', 'Gyrus Cinguli', 'Male', 'Neurons', 'Pain', 'Rats', 'Rats, Sprague-Dawley'] | 29,844,413 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.425.179.308'], ['E07.305.250'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['A08.675', 'A11.671'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['B01.050.150.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulation defects in Riata implantable cardioverter-defibrillator leads. | BACKGROUND: The structures composing implantable cardioverter-defibrillator (ICD) leads have become more complicated and thinner with technological advances. Silicon insulation defects with and without clinically manifested electrical abnormalities have been reported in Riata leads (St. Jude Medical).OBJECTIVE: The aim... | ['Adult', 'Aged', 'Brugada Syndrome', 'Defibrillators, Implantable', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Japan', 'Male', 'Middle Aged', 'Prosthesis Failure', 'Radiography, Thoracic', 'Tachycardia, Ventricular', 'Time Factors', 'Young Adult'] | 23,037,457 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.322', 'C14.280.123.250', 'C16.320.100'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E05.320'], ['E05.325.192'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Quantitative structure activity relationship of IA3-like peptides as aspartic proteinase inhibitors. | The IA(3) polypeptide inhibitor from Saccharomyces cerevisiae interacts potently and selectively with its target, the S. cerevisiae vacuolar aspartic proteinase (ScPr). Upon encountering the enzyme, residues 2-32 of the intrinsically unstructured IA(3) polypeptide become ordered into an almost-perfect alpha-helix. In p... | ['Alanine', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Aspartic Acid Endopeptidases', 'Computer Simulation', 'Escherichia coli', 'Hydrogen-Ion Concentration', 'Models, Molecular', 'Molecular Sequence Data', 'Mutation', 'Quantitative Structure-Activity Relationship', 'Recombinant Proteins', 'Reproducibility of R... | 19,003,993 | [['D12.125.042'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['L01.224.160'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.300'], ['E05.599.595'], ['L01.453.245.667'], ['G05.365.590'], ['G02.111.830.500', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Contribution of LHX4 Mutations to Pituitary Deficits in a Cohort of 417 Unrelated Patients. | Context: LHX4 encodes a LIM-homeodomain transcription factor that is implicated in early pituitary development. In humans, only 13 heterozygous LHX4 mutations have been associated with congenital hypopituitarism.Objective: The aims of this study were to evaluate the prevalence of LHX4 mutations in patients with hypopit... | ['Adolescent', 'Amino Acid Sequence', 'Biomarkers', 'Blotting, Western', 'Child', 'Child, Preschool', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Hypopituitarism', 'Immunoprecipitation', 'Infant', 'Infant, Newborn', 'LIM-Homeodomain Proteins', 'Male', 'Mutation', 'Pedigree', 'Prognosis', 'Sequence Homol... | 27,820,671 | [['M01.060.057'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D23.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249',... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Citrinin Monomer and Dimer Derivatives with Antibacterial and Cytotoxic Activities Isolated from the Deep Sea-Derived Fungus Penicillium citrinum | Two previously unreported citrinin dimer derivatives, penicitol D (1) and 1-epi-citrinin H1 (2), were isolated from the culture of a deep sea-derived fungus Penicillium citrinum NLG-S01-P1, together with 11 biogenetic related compounds (3⁻13). A plausible biogenetic pathway for compounds 2⁻4 was proposed. Their structu... | ['A549 Cells', 'Anti-Bacterial Agents', 'Antineoplastic Agents', 'Aquatic Organisms', 'Bacteria', 'Cell Survival', 'Citrinin', 'Humans', 'Models, Molecular', 'Molecular Structure', 'Penicillium'] | 30,634,700 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['D27.505.954.122.085'], ['D27.505.954.248'], ['B05.080', 'G16.500.275.725.500.650.075'], ['B03'], ['G04.346'], ['D03.383.663.283.320', 'D03.633.100.150.320', 'D23.946.587.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['G02.111.5... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rheumatoid factor and HLA antigens in wrist tenosynovitis and humeral epicondylitis. | A matched case-referent study was undertaken to assess whether rheumatoid factor (RF) is associated with repeating tenosynovitis or peritendinitis and whether HLA-B27 predisposes to epicondylitis. The study subjects consisted of 25 workers in manually strenuous jobs with a history of at least two episodes of tenosynovi... | ['Case-Control Studies', 'Cumulative Trauma Disorders', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'HLA Antigens', 'Humans', 'Latex Fixation Tests', 'Male', 'Rheumatoid Factor', 'Tennis Elbow', 'Tenosynovitis', 'Wrist Joint'] | 7,777,826 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C26.844.150'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of candidemia in epidemiology and risk factors among cancer patients in a cancer center of China: an 8-year case-control study. | BACKGROUND: Candidemia is the worldwide life-threaten disease, especially in cancer patients. This study was aimed to identify and evaluate the risk factors of candidemia in cancer patients, which will prompt the improvement on current therapeutic strategies and prognosis.METHODS: A retrospective, case-control study wa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Candida', 'Candida albicans', 'Candida glabrata', 'Candidemia', 'Case-Control Studies', 'Catheter-Related Infections', 'China', 'Female', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Neoplasms', 'Prevalence', 'Prognosis', 'Retrospective Studies', 'Risk Factors... | 28,768,479 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['B01.300.107.795.095.400', 'B01.300.381.147.400', 'B01.300.930.176.400'], ['C01.150.703.160.175.500', 'C01.150.703.49... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The role of cytotoxic and regulatory T cells in relapsed/refractory Hodgkin lymphoma. | Recent data suggests the presence of cytotoxic (TIA-1 and granzyme B+) and regulatory T-cells (FOXP3+) in classical Hodgkin lymphoma (cHL) tissues has been shown to correlate with poor overall survival in mainly diagnostic biopsies. By tissue microarray analyses, we extend this observation to a cohort of relapsed/refra... | ['Adolescent', 'Adult', 'Biopsy', 'Drug Resistance, Neoplasm', 'Female', 'Forkhead Transcription Factors', 'Granzymes', 'Hodgkin Disease', 'Humans', 'Immunochemistry', 'Male', 'Microarray Analysis', 'Middle Aged', 'Poly(A)-Binding Proteins', 'Predictive Value of Tests', 'Prognosis', 'Recurrence', 'Survival Analysis', '... | 20,065,852 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['G07.690.773.984.395'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['D08.811.277.656.300.760.397', 'D08.811.277.656.959.350.397'], ['C04... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A case report of pulmonary adenocarcinoma responding to (glycolato-0,0') diammineplatinum (II), a new platinum complex. | The first patient to respond to [(glycolato-0,0') diammineplatinum (II)] (254-S) in a clinical phase I study is reported. The patient was a 52-year-old man complaining of nausea and weight loss. A chest X-ray demonstrated a diffuse infiltrating shadow in the right lung. A transbronchoscopic brushing of the right upper ... | ['Adenocarcinoma', 'Antineoplastic Agents', 'Clinical Trials as Topic', 'Humans', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Organoplatinum Compounds'] | 3,312,721 | [['C04.557.470.200.025'], ['D27.505.954.248'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['D02.691.788']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunization attitudes and practices among family medicine providers. | OBJECTIVE: To describe immunization attitudes and practices among family medicine providers across New York State.METHODS: In this cross-sectional survey study, family medicine providers across New York State completed a questionnaire to assess vaccine beliefs and barriers and immunization practices.STATISTICAL ANALYSI... | ['Adolescent', 'Child', 'Cross-Sectional Studies', 'Diphtheria-Tetanus-Pertussis Vaccine', 'Family Practice', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Personnel', 'Humans', 'Immunization', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'New York', 'Papillomavirus Infections', 'Papillomavirus Vaccin... | 29,028,414 | [['M01.060.057'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D20.215.894.135.535.300', 'D20.215.894.691.263.300', 'D20.215.894.691.824.300', 'D20.215.894.815.300'], ['H02.403.340.500'], ['F01.100.150.500', 'N05.300.150.410'], ['M01.526.485', 'N02.360'], ['B01.050.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Dimer Interface of the Human Serotonin Transporter and Effect of the Membrane Composition. | The oligomeric state of membrane proteins has recently emerged in many cases as having an effect on their function. However, the intrinsic dynamics of their spatial organization in cells and model systems makes it challenging to characterize. Here we use molecular dynamics (MD) simulations at multiple resolutions to de... | ['Cell Membrane', 'Cholesterol', 'Humans', 'Molecular Dynamics Simulation', 'Phosphatidylinositols', 'Protein Conformation', 'Protein Conformation, alpha-Helical', 'Protein Multimerization', 'Protein Stability', 'Serotonin Plasma Membrane Transport Proteins'] | 29,572,541 | [['A11.284.149'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D10.570.755.375.760.400.942'], ['G02.111.570.820.709'], ['G02.111.570.820.709.600.020'], ['G02.111.694'], ['G02.111.7... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Can alterations in integrin and laminin-5 expression be used as markers of malignancy? | Development of squamous cell carcinomas (SCCs) involves alterations in the adhesive interactions in the epithelium and invasion through the basement membrane. Therefore, changes in the expression of receptors and ligands involved in cell-cell and cell-matrix adhesion may be essential for the transformation of a premali... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Cell Adhesion Molecules', 'Humans', 'Integrins', 'Leukoplakia, Oral', 'Middle Aged', 'Precancerous Conditions'] | 10,052,726 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408'], ['C04.588.443.591.545', 'C04.834.512.513', 'C0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Suppression of ERK1/2 and hypoxia pathways by four Phyllanthus species inhibits metastasis of human breast cancer cells. | Chemotherapies remain far from ideal due to drug resistance; therefore, novel chemotherapeutic agents with higher effectiveness are crucial. The extracts of four Phyllanthus species, namely Phyllanthus niruri, Phyllanthus urinaria, Phyllanthus watsonii, and Phyllanthus amarus, were shown to induce apoptosis and inhibit... | ['Breast Neoplasms', 'Cell Hypoxia', 'Humans', 'MAP Kinase Signaling System', 'MCF-7 Cells', 'Phyllanthus', 'Plant Extracts', 'Vascular Endothelial Growth Factor A'] | 28,911,625 | [['C04.588.180', 'C17.800.090.500'], ['G03.197.300', 'G04.270.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['A11.251.210.190.630'], ['B01.650.940.800.575.912.250.859.797.438.622'], ['D20.215.784.500', 'D26.667'], ['D12.644.276.100.800.200', 'D12.776.467.100.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Local anaesthesia for carpal tunnel decompression: a comparison of two techniques. | Carpal tunnel decompression is mostly performed as a day case procedure using local anaesthesia. The local anaesthetic is commonly administered by subcutaneous infiltration alone (the Gale technique) or by infiltration of the local anaesthetic into the carpal tunnel in addition to the subcutaneous infiltration (the Alt... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anesthesia, Local', 'Carpal Tunnel Syndrome', 'Decompression, Surgical', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Pain, Postoperative', 'Single-Blind Method'] | 17,046,117 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E03.155.086.231'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['C23.550.767.700', 'C23.888.592.612.832'], ['E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Trypanocidal effect of the benzyl ester of N-propyl oxamate: a bi-potential prodrug for the treatment of experimental Chagas disease. | BACKGROUND: Chagas disease, which is caused by Trypanosoma cruzi, is a major health problem in Latin America, and there are currently no drugs for the effective treatment of this disease. The energy metabolism of T. cruzi is an attractive target for drug design, and we previously reported that inhibitors of á-hydroxy a... | ['Alcohol Oxidoreductases', 'Animals', 'Cell Line', 'Cell Survival', 'Chagas Disease', 'Disease Models, Animal', 'Esters', 'Isoenzymes', 'Male', 'Mice', 'Nifurtimox', 'Nitroimidazoles', 'Oxamic Acid', 'Prodrugs', 'Trypanocidal Agents', 'Trypanosoma cruzi'] | 25,896,924 | [['D08.811.682.047'], ['B01.050'], ['A11.251.210'], ['G04.346'], ['C01.610.752.300.900.200', 'C01.920.625'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.241.400'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.640.600.480', 'D02.886.665.400', 'D03.383.312.649.480', 'D03... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Internal containment in the treatment of patients with dissociative disorders. | Both external and internal containment techniques are useful in treating patients with multiple personality disorder and other dissociative disorders. The author focuses on internal containment using various individualized strategies for helping these patients cope with life and work through past traumas. Because the v... | ['Adaptation, Psychological', 'Affect', 'Anger', 'Dissociative Disorders', 'Ego', 'Female', 'Humans', 'Impulsive Behavior', 'Male', 'Memory', 'Psychotherapy', 'Religion and Psychology'] | 8,401,387 | [['F01.058'], ['F01.470.047'], ['F01.470.093'], ['F03.300'], ['F01.752.747.189', 'F02.739.794.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F02.463.425.540'], ['F04.754'], ['F02.880', 'K01.844.664']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Survey of ophthalmic anterior segment findings and intraocular pressure in 95 North American box turtles (Terrapene spp.). | OBJECTIVE: To describe the ophthalmic biomicroscopy findings and intraocular pressures (IOP) in a captive population of box turtles and to determine whether a relationship exists between body morphometrics or health status and IOP.PROCEDURES: Hundred and three box turtles (69 Gulf coast, 24 three-toed, one ornate, one ... | ['Animals', 'Anterior Eye Segment', 'Body Size', 'Female', 'Intraocular Pressure', 'Male', 'Reference Values', 'Species Specificity', 'Turtles'] | 25,683,768 | [['B01.050'], ['A09.371.060'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['G14.440'], ['E05.978.810'], ['G16.824'], ['B01.050.150.900.833.848']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feasibility of tissue re-biopsy in non-small cell lung cancers resistant to previous epidermal growth factor receptor tyrosine kinase inhibitor therapies. | BACKGROUND: When epidermal growth factor receptor (EGFR) gene mutation-positive non-small cell lung cancer (NSCLC) acquires resistance to the initial tyrosine kinase inhibitor (TKI) treatment, reassessing the tumor DNA by re-biopsy is essential for further treatment selection. However, the process of TKI-sensitive tumo... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Biopsy', 'Biopsy, Needle', 'Bronchoscopy', 'Carcinoma, Non-Small-Cell Lung', 'Cohort Studies', 'Disease Progression', 'Drug Resistance, Neoplasm', 'ErbB Receptors', 'Feasibility Studies', 'Female', 'Humans', 'Image-Guided Biopsy', 'Lung Neoplasms', 'Male', 'Midd... | 29,212,495 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Abnormal placement of the testes]. | The authors defined a uniform classification of abnormal positions of the testes. They recommend also a uniform therapeutic procedure: after the first year of life treatment with human chorionic gonadotropin in one or two curves, if orchiopexy fails. | ['Cryptorchidism', 'Humans', 'Infant', 'Male', 'Testis'] | 1,981,863 | [['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antipsychotic Use Among Adult Outpatients and Venous Thromboembolic Disease: A Retrospective Cohort Study. | BACKGROUND: Treatment with antipsychotic (AP) agents is associated with incident thromboembolic events. However, the underpinnings of this association remain unknown. We sought to evaluate the effect of AP agents-categorized by their metabolic/sedative and hyperprolactinemia adverse effect profile-on the risk of venous... | ['Adult', 'Aged', 'Aged, 80 and over', 'Ambulatory Care', 'Antipsychotic Agents', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Outpatients', 'Retrospective Studies', 'Venous Thromboembolism'] | 28,622,161 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1). | Activation of cAMP signaling pathway and its transcriptional factor cyclic AMP response element binding protein (CREB) and coactivator are key determinants of neuronal differentiation and plasticity. We show that nuclear fibroblast growth factor receptor-1 (FGFR1) mediates cAMP-induced neuronal differentiation and regu... | ['Active Transport, Cell Nucleus', 'Bucladesine', 'CREB-Binding Protein', 'Cell Differentiation', 'Cell Nucleus', 'Cells, Cultured', 'Cyclic AMP', 'Cyclic AMP Response Element-Binding Protein', 'Fibroblast Growth Factor 2', 'Genes, Dominant', 'Humans', 'Mutagenesis, Site-Directed', 'Neurites', 'Neurofilament Proteins',... | 12,614,330 | [['G03.143.310.100', 'G03.143.700.100'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['D08.811.913.050.134.415.500.575.249', 'D12.776.930.680.300'], ['G04.152'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['D03.633.100.759.646.1... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low-dose follicular-phase cocaine administration disrupts menstrual and ovarian cyclicity in rhesus monkeys. | OBJECTIVE: To evaluate the effects of daily low-dose follicular-phase cocaine administration on menstrual cyclicity, ovulation rates, corpus luteum function, and hormone levels in rhesus monkeys.METHOD: Normally cycling, drug-naive, adult rhesus monkeys were randomized to receive either 1 mg/kg of cocaine (n = 7), 2 mg... | ['Animals', 'Cocaine', 'Corpus Luteum', 'Estradiol', 'Female', 'Follicle Stimulating Hormone', 'Follicular Phase', 'Luteal Phase', 'Luteinizing Hormone', 'Macaca mulatta', 'Menstrual Cycle', 'Ovulation', 'Progesterone'] | 10,205,779 | [['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['A05.360.319.114.630.278', 'A06.300.312.497.278'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['G08.686.605.310... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification, characterization and cytotoxicity in vitro assay of nitazoxanide major degradation product. | Stress studies of the broad-spectrum antiparasitic nitazoxanide were conducted in order to isolate and elucidate the major degradation product involved in thermal, acid, alkaline, oxidative and photolytic decomposition of the drug in solution and solid state. The major degradation product was identified and characteriz... | ['Antiparasitic Agents', 'Cell Survival', 'Humans', 'Safety', 'Thiazoles', 'Toxicity Tests'] | 22,483,900 | [['D27.505.954.122.250'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.135.060.075'], ['D02.886.675', 'D03.383.129.708'], ['E05.940']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Regulation of mucosal IgA responses in vivo: cytokines and adjuvants. | The predominance of IgA plasma cells at mucosal sites reflects a combination of the selective localisation and vigorous proliferation after extravasation of IgA plasma cell precursors. Experiments are described here which demonstrate that post-extravasation events leading to IgA precursor cell retention, proliferation ... | ['Adjuvants, Immunologic', 'Animals', 'Cytokines', 'Immunity, Mucosal', 'Immunoglobulin A', 'Immunotherapy', 'Interleukin-6', 'Mice', 'Mice, Transgenic', 'Ovalbumin', 'Plasma Cells'] | 8,988,863 | [['D27.505.696.477.067'], ['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.450.573'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['E02.095.465.425'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measuring the psychosocial impact of population-based prostate-specific antigen testing for prostate cancer in the UK. | OBJECTIVE: To evaluate the psychosocial impact of participation in a population-based prostate-specific antigen (PSA) testing programme, akin to screening, and to explore the relationship between urinary symptoms reported before PSA testing and the response to the subsequent PSA result.PATIENTS AND METHODS: This prospe... | ['Aged', 'Biopsy', 'Feasibility Studies', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Prospective Studies', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Psychiatric Status Rating Scales', 'Surveys and Questionnaires'] | 16,978,272 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
'Sufficient' absorption--a quantitative method to replace 'exhaustive' absorption. | At present, the only guideline for removal of undesired reactivities from an antiserum is that no activity against the cross-reacting (undesired) antigens should remain after exhaustive absorption. Since this guideline sets no upper limit on the amount of undesired antigens required for an exhaustive absorption, waste ... | ['ABO Blood-Group System', 'Absorption', 'Animals', 'Antibody Specificity', 'Antigens', 'Chickens', 'Erythrocytes', 'Hemagglutination Tests', 'Humans', 'Immune Sera', 'Immunodiffusion', 'Isoantibodies', 'Lewis Blood Group Antigens', 'Rabbits'] | 808,569 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['G12.100'], ['D23.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.225.812.735.050.375', 'E05.200.812.735... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bezafibrate induces acyl-CoA oxidase mRNA levels and fatty acid peroxisomal beta-oxidation in rat white adipose tissue. | Rats treated with bezafibrate, a PPAR activator, gain less body weight and increase daily food intake. Previously, we have related these changes to a shift of thermogenesis from brown adipose tissue to white adipose tissue attributable to bezafibrate, which induces uncoupling proteins (UCP), UCP-1 and UCP-3, in rat whi... | ['Acyl-CoA Oxidase', 'Adipose Tissue', 'Animals', 'Bezafibrate', 'Body Weight', 'Cells, Cultured', 'Cholesterol', 'Fatty Acids', 'Hypolipidemic Agents', 'Leptin', 'Liver', 'Male', 'Oxidoreductases', 'Oxygen', 'Peroxisomes', 'RNA', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Cytoplasmic and Nuclear', '... | 11,216,866 | [['D08.811.682.660.150.200', 'D12.776.331.149'], ['A10.165.114'], ['B01.050'], ['D02.065.277.067', 'D02.241.081.114.968.500.249', 'D02.241.223.100.100.120', 'D02.241.223.100.200.249', 'D02.355.726.305.249', 'D02.455.426.559.389.127.085.101', 'D02.455.426.559.389.127.250.249', 'D02.455.426.559.389.657.654.305.249'], ['C... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Results of shoulder hemiarthroplasty in patients with acute and old fractures of the proximal humerus]. | STUDY-DESIGN: We report on a prospective study of 22 patients after shoulder hemiarthroplasty in acute and old proximal humerus fractures.METHOD: Nine patients with an acute and 13 with an old humerus fracture, in whom a hemiarthroplasty was performed have been evaluated clinically using the Constant score as well as r... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty', 'Female', 'Humans', 'Humerus', 'Male', 'Middle Aged', 'Prospective Studies', 'Shoulder Fractures', 'Treatment Outcome'] | 10,327,557 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110', 'E04.680.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C26.404.625', 'C26.803.250'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Influence of nuclear factor-kappaB decoy transfection on nuclear factor-kappaB activity and vascular endothelial growth factor/urokinase-type plasminogen activator/intercellular cell adhesion molecule-1 level of SKOV3 cells]. | OBJECTIVE: To investigate the effect of nuclear factor-kappaB (NF-kappaB) decoy oligodeoxynucleotides (ODN) on NF-kappaB activation and expressions of vascular endothelial growth factor (VEGF), urokinase-type plasminogen activator (uPA), intercellular cell adhesion molecule-1 (ICAM-1) of SKOV3 cell.METHODS: After trans... | ['Cystadenocarcinoma, Serous', 'Female', 'Genetic Therapy', 'Humans', 'Intercellular Adhesion Molecule-1', 'NF-kappa B', 'Oligodeoxyribonucleotides', 'Ovarian Neoplasms', 'Transfection', 'Tumor Cells, Cultured', 'Urokinase-Type Plasminogen Activator', 'Vascular Endothelial Growth Factor A'] | 15,363,352 | [['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['E02.095.301', 'E05.393.420.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.200.450', 'D12.776.543.550.200.450', 'D23.050.301.350.450'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['D13.695.578.424.450... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimizing bead size reduces errors in force measurements in optical traps. | Optical traps are used to measure force (F) over a wide range (0.01 to 1,000 pN). Variations in bead radius (r) hinder force precision since trap stiffness (k(trap)) varies as r3 when r is small. Prior work has shown k(trap) is maximized when r is approximately equal to the beam waist (w0), which on our instrument was ... | ['Biophysics', 'Calibration', 'DNA', 'Hydrodynamics', 'Kinetics', 'Lasers', 'Light', 'Nucleic Acid Conformation', 'Optical Tweezers', 'Optics and Photonics', 'Particle Size', 'Reproducibility of Results', 'Stress, Mechanical', 'Time Factors'] | 23,388,894 | [['H01.158.344', 'H01.671.100'], ['E05.978.155'], ['D13.444.308'], ['G01.342'], ['G01.374.661', 'G02.111.490'], ['E07.632.490', 'E07.710.520'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G02.111.570.820.486', 'G05.360.580'], ['E05.650'], ['H01.671.617', 'J01.293.688'], ['G02.712'], ... | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Zebrafish lacking functional DNA polymerase gamma survive to juvenile stage, despite rapid and sustained mitochondrial DNA depletion, altered energetics and growth. | DNA polymerase gamma (POLG) is essential for replication and repair of mitochondrial DNA (mtDNA). Mutations in POLG cause mtDNA instability and a diverse range of poorly understood human diseases. Here, we created a unique Polg animal model, by modifying polg within the critical and highly conserved polymerase domain i... | ['Adenosine Triphosphate', 'Animal Fins', 'Animals', 'DNA Polymerase gamma', 'DNA, Mitochondrial', 'DNA-Directed DNA Polymerase', 'Genetic Engineering', 'Glycolysis', 'Models, Animal', 'Mutation', 'Oxygen Consumption', 'Regeneration', 'Survival Analysis', 'Zebrafish', 'Zebrafish Proteins'] | 26,519,465 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A13.075'], ['B01.050'], ['D08.811.913.696.445.308.300.169', 'D12.776.575.280'], ['D13.444.308.283.225'], ['D08.811.913.696.445.308.300'], ['E05.393.420'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['E05.598'], ['G0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolation and Manufacture of Clinical-Grade Bone Marrow-Derived Human Mesenchymal Stromal Cells. | Mesenchymal stromal cells (MSCs) are multipotent cells with both regenerative and immunomodulatory capacities. These unique properties make them appealing as a biologic, with multiple phase 1-3 clinical trials currently testing their safety and efficacy. Although expanding MSCs does not require extensive manipulation, ... | ['Cell Culture Techniques', 'Cell Differentiation', 'Cell Proliferation', 'Cell Separation', 'Cells, Cultured', 'Clinical Protocols', 'Clinical Trials as Topic', 'Guideline Adherence', 'Humans', 'Immunophenotyping', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Specimen Handling'] | 27,236,680 | [['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['E02.183', 'N05.715.360.330.125'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An unusually hard lesion in an aortocoronary saphenous vein graft refractory to standard balloon angioplasty. | We report a case of a hard lesion in the body of an aortocoronary saphenous vein graft, which developed 3 years after bypass surgery and was not amenable to dilation during percutaneous coronary angioplasty, despite multiple balloon inflations at pressures reaching 13 atm. Hard lesions in aortocoronary saphenous vein g... | ['Angioplasty, Balloon', 'Arteriosclerosis', 'Constriction, Pathologic', 'Coronary Artery Bypass', 'Graft Occlusion, Vascular', 'Humans', 'Male', 'Middle Aged', 'Saphenous Vein', 'Treatment Failure'] | 8,749,870 | [['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137.126'], ['C23.300.287'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C23.550.767.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.015.908.819'], ['E01.78... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The inverse relationship between number of steps per day and obesity in a population-based sample: the AusDiab study. | BACKGROUND: Physical activity (PA) is inversely associated with obesity but the effect has been difficult to quantify using questionnaires. In particular, the shape of the association has not yet been well described. Pedometers provide an opportunity to better characterize the association.METHODS: Residents of househol... | ['Adult', 'Australia', 'Body Mass Index', 'Cross-Sectional Studies', 'Female', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Obesity', 'Walking'] | 17,047,641 | [['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cryptococcal choroid plexitis: rare imaging findings of central nervous system cryptococcal infection in an immunocompetent individual. | Central nervous system (CNS) cryptococcosis is a common opportunistic fungal infection in immunocompromised patients, and the imaging findings differ from those in immunocompetent patients. Here, we present the imaging findings in an immunocompetent woman of a rare case of central nervous system cryptococcal choroid pl... | ['Aged', 'Choroid Plexus', 'Cryptococcus neoformans', 'Female', 'Headache', 'Humans', 'Immunocompetence', 'Magnetic Resonance Imaging', 'Meningitis, Cryptococcal', 'Vomiting'] | 20,139,243 | [['M01.060.116.100'], ['A08.186.211.140.298'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.460'], ['E01.370.350.825.500'], ['C01.150.703.181.500.500', 'C01.150.703.248.290', 'C01.207.198.500.500', 'C10.228.228.198.500.500', 'C10.228.614... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neurocomputational mechanisms underlying subjective valuation of effort costs. | In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort can be experienced in different domains, with some tasks requiring significant cognitive demand and others being more physically effortful. The motivation to exert effort for reward is highly subjective and varies consider... | ['Adult', 'Amygdala', 'Brain', 'Choice Behavior', 'Cognition', 'Computer Simulation', 'Female', 'Humans', 'Logistic Models', 'Magnetic Resonance Imaging', 'Male', 'Models, Neurological', 'Physical Exertion', 'Reaction Time', 'Reward', 'Risk', 'Task Performance and Analysis', 'Young Adult'] | 28,234,892 | [['M01.060.116'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['A08.186.211'], ['F02.463.785.373.346'], ['F02.463.188'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
BK virus encephalopathy and sclerosing vasculopathy in a patient with hypohidrotic ectodermal dysplasia and immunodeficiency. | Human BK polyomavirus (BKV) is reactivated under conditions of immunosuppression leading most commonly to nephropathy or cystitis; its tropism for the brain is rare and poorly understood. We present a unique case of BKV-associated encephalopathy in a man with hypohidrotic ectodermal dysplasia and immunodeficiency (HED-... | ['Adult', 'BK Virus', 'Brain', 'Brain Diseases', 'Ectodermal Dysplasia 1, Anhidrotic', 'Humans', 'I-kappa B Kinase', 'Immunologic Deficiency Syndromes', 'Male', 'Polyomavirus Infections'] | 27,411,570 | [['M01.060.116'], ['B04.280.210.700.615.100', 'B04.613.204.670.615.100'], ['A08.186.211'], ['C10.228.140'], ['C16.131.077.350.198', 'C16.131.831.350.198', 'C16.320.322.116', 'C16.320.850.250.198', 'C17.800.804.350.198', 'C17.800.827.250.198'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.7... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Performance characteristics of beta-2-microglobulin measurements on a Beckman Immage analyzer with the DakoCytomation reagent kit. | OBJECTIVE: Evaluation of serum beta-2-microglobulin (beta2M) in an automated analyzer.DESIGN AND METHODS: The DakoCytomation beta2M kit is an antibody based reagent intended for quantitative determination of beta2M in serum and plasma by rate nephelometry.RESULTS: The limit of blank is 0.16 mg/L. The method is linear u... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Immunoassay', 'Male', 'Middle Aged', 'Nephelometry and Turbidimetry', 'Reagent Kits, Diagnostic', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Young Adult', 'beta 2-Microglobulin'] | 19,643,100 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['M01.060.116.630'], ['E05.196.712.650'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Comparative study on remote sensing invertion methods for estimating winter wheat leaf area index]. | The present study aims to explore capability of different methods for winter wheat leaf area index inversion by integrating remote sensing image and synchronization field experiment. There were four kinds of LAI inversion methods discussed, specifically, support vector machines (SVM), discrete wavelet transform (DWT), ... | ['Models, Theoretical', 'Plant Leaves', 'Principal Component Analysis', 'Regression Analysis', 'Remote Sensing Technology', 'Support Vector Machine', 'Triticum', 'Wavelet Analysis'] | 25,095,437 | [['E05.599'], ['A18.024.812'], ['E05.318.740.562'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E01.370.520.750.500', 'E05.925.500', 'L01.178.847.675.500'], ['G17.035.250.500.500.500', 'L01.224.050.375.530.500.500'], ['B01.650.940.800.575.912.250.822.918'], ['E05.959', 'G17.915', 'L01.224.800.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Invasive pulmonary aspergillosis in AIDS: radiographic, CT, and pathologic findings. | PURPOSE: To review the radiographic and computed tomographic (CT) manifestations of invasive pulmonary aspergillosis and to correlate the imaging and pathologic findings in patients with acquired immunodeficiency syndrome (AIDS).MATERIALS AND METHODS: Chest radiographs, CT scans, and pathologic specimens were reviewed ... | ['AIDS-Related Opportunistic Infections', 'Adult', 'Aspergillosis', 'Aspergillus fumigatus', 'Humans', 'Lung', 'Lung Diseases, Fungal', 'Male', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 7,617,853 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['M01.060.116'], ['C01.150.703.080'], ['B01.300.381.081.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C01.150.703.534', 'C01.748.435', 'C08.381.472', 'C08.730.435'], ... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Brazilian adolescents' knowledge and beliefs about abortion methods: a school-based internet inquiry. | BACKGROUND: Internet surveys that draw from traditionally generated samples provide the unique conditions to engage adolescents in exploration of sensitive health topics.METHODS: We examined awareness of unwanted pregnancy, abortion behaviour, methods, and attitudes toward specific legal indications for abortion via a ... | ['Abortion, Induced', 'Adolescent', 'Brazil', 'Child', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Internet', 'Male', 'Peer Group', 'Pregnancy', 'Pregnancy in Adolescence', 'Pregnancy, Unwanted', 'Schools', 'Sex Factors', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Young Adult'] | 24,521,075 | [['E04.520.050'], ['M01.060.057'], ['Z01.107.757.176'], ['M01.060.406'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F01.829.316.483'], ['G08.686.784.769'], ['G08.686.784.769.494'], ['G08.686.784.769.580'], ['I02.783', 'J03.832'], ['N05.715.350.675... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, In... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
[Transforming of the drug resistance plasmid from Staphylococcus aureus into Escherichia coli]. | OBJECTIVE: To discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli.METHODS: The chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensi... | ['Drug Resistance, Bacterial', 'Escherichia coli', 'Plasmids', 'Staphylococcus', 'Transformation, Bacterial'] | 21,097,411 | [['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.600'], ['B03.300.390.400.800.750', 'B03.353.500.750.750', 'B03.510.100.750.750', 'B03.510.400.790.750'], ['E05.393.350.810.500', 'G05.728.860.500', 'G05.728.865.820', 'G06.099.850']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The systemic lupus erythematosus (SLE) disease autoantigen-calreticulin can inhibit C1q association with immune complexes. | Following its release from cells during infection and inflammation, calreticulin (CRT) can act as an autoantigen in diseases such as SLE. Why CRT is a target of protective immunity and whether it may interfere with innate immunity once released from cells during inflammation is unclear. In the present study, we found t... | ['Adult', 'Antigen-Antibody Complex', 'Autoantibodies', 'Autoantigens', 'Binding Sites', 'Calcium-Binding Proteins', 'Calreticulin', 'Complement C1q', 'Complement Inactivator Proteins', 'Humans', 'Immunoglobulin G', 'Lupus Erythematosus, Systemic', 'Protein Binding', 'Ribonucleoproteins'] | 9,158,084 | [['M01.060.116'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['G02.111.570.120'], ['D12.776.157.125'], ['D12.644.360.372.374', 'D12.776.157.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cost-utility analysis comparing meropenem with imipenem plus cilastatin in the treatment of severe infections in intensive care. | This study compared the cost-effectiveness of meropenem with that of imipenem plus cilastatin in the treatment of severe infections in hospital intensive care in the UK. A Markov model was constructed to model lifetime costs and quality-adjusted life years (QALYs) of using meropenem and imipenem plus cilastatin for the... | ['Aged', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Cilastatin', 'Cohort Studies', 'Cost-Benefit Analysis', 'Decision Support Techniques', 'Dipeptidases', 'Drug Combinations', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Markov Chains', 'Meropenem', 'Middle Aged', 'Quality-Adjusted Life Years', 'Sensitiv... | 16,429,296 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['C01.150.252'], ['D02.455.426.392.368.533.200', 'D10.251.355.325.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N03.219.151.125'], ['E05.245', 'L01.313.500.750.190'], ['D08.811.277.656.350.297'], ['D26.310'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance. | PURPOSE: To study the in vitro and in vivo interaction of chitosan nanoparticles (CSNPs), a new particulate drug carrier, with epithelial cells on the ocular surface.METHODS: CSNPs labeled with fluorescein isothiocyanate-bovine serum albumin were produced by ionotropic gelation. Human conjunctival epithelial cells (IOB... | ['Animals', 'Biological Transport', 'Cell Count', 'Cell Survival', 'Cells, Cultured', 'Chitosan', 'Conjunctiva', 'Cornea', 'Drug Carriers', 'Epithelial Cells', 'Female', 'Fluorescein-5-isothiocyanate', 'Fluorophotometry', 'Humans', 'Microscopy, Confocal', 'Microspheres', 'Rabbits', 'Serum Albumin, Bovine'] | 16,565,375 | [['B01.050'], ['G03.143'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'], ['A11.251'], ['D05.750.078.139.500', 'D09.698.211.500'], ['A09.371.060.200', 'A09.371.337.168'], ['A09.371.060.217'], ['D26.255.260', 'E02.319.300.380'], ['A11.436'], ['D02.455.426.779.347.400', 'D02.500.375.25... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postnatal deficiency of omega-3 fatty acids in monkeys: fluid intake and urine concentration. | Previous studies demonstrated increased fluid intake in rhesus monkeys exposed to combined prenatal and long-term postnatal (PRE+POST) dietary deficiency of omega-3 fatty acids. Here we determined the effect of dietary deficiency in omega-3 fatty acids occurring only prenatally (PRE) or only postnatally (POST). Water i... | ['Aging', 'Animals', 'Drinking', 'Erythrocytes', 'Fatty Acids, Omega-3', 'Female', 'Kidney Concentrating Ability', 'Male', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Sodium Chloride', 'Water-Electrolyte Balance'] | 1,523,223 | [['G07.345.124'], ['B01.050'], ['G07.203.650.283.249', 'G10.261.330.249'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['G08.852.536'], ['G08.686.784.769'], ['C13.703.824.500'], ['D01.210.450.150.875', 'D01.857.650'], ['G02.111.635.500', 'G03.615.500... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glenohumeral articular contact areas and pressures following labral and osseous injury to the anteroinferior quadrant of the glenoid. | The objective of this study was to determine the effect of progressive labral and bone loss on the articular contact area and pressures across the glenohumeral joint under compressive loads of 220 and 440 N. Eight fresh-frozen cadaver shoulders were used, and contact pressures in 4 quadrants of the glenoid were determi... | ['Adult', 'Biomechanical Phenomena', 'Humans', 'Joint Instability', 'Pressure', 'Shoulder Joint'] | 12,378,162 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['G01.374.715'], ['A02.835.583.748']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of testicular androgenesis by urinary antigonadotropins and melatonin in rats. | Comparative in vitro and in vivo studies of the effects of urinary gonadotropin-inhibiting substances and melatonin on the androgenesis in rat testicular homogenates were performed. When the urinary extract containing the inhibiting substances or melatonin was added directly to the incubation medium, and was also injec... | ['Androstenedione', 'Animals', 'Chorionic Gonadotropin', 'Male', 'Melatonin', 'Pineal Gland', 'Rats', 'Testis', 'Testosterone'] | 499,096 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hydrogen peroxide enhances signal-responsive arachidonic acid release from neurons: role of mitogen-activated protein kinase. | Hydrogen peroxide (H2O2) is a potent stimulator of signal-responsive phospholipase A2 (PLA2) in vascular smooth muscle and cultured endothelial cells. We investigated whether H2O2 plays a similar regulatory role in neurons. H2O2 did not stimulate a release of arachidonic acid from cultured neurons when applied alone bu... | ['Animals', 'Arachidonic Acid', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cells, Cultured', 'Corpus Striatum', 'Drug Synergism', 'Enzyme Inhibitors', 'Excitatory Amino Acid Agonists', 'Glutamic Acid', 'Hydrogen Peroxide', 'Mice', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Mitoge... | 9,572,294 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['A11.251'], ['A08.186.211.200.885.287.249.487'], ['G07.690.773.968.477'], ['D27.505.519.389'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['D12.125.067.625.349',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The contribution of emotion regulation difficulties to risky sexual behavior within a sample of patients in residential substance abuse treatment. | The present study examined the unique contribution of emotion regulation difficulties to past-year risky sexual behavior (RSB) among substance use disorder (SUD) patients (above and beyond other known RSB risk factors). A sample of 177 SUD patients completed a series of questionnaires. At the zero-order level, emotion ... | ['Adolescent', 'Adult', 'Emotions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Residential Treatment', 'Risk Factors', 'Risk-Taking', 'Sexual Behavior', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Young Adult'] | 22,658,304 | [['M01.060.057'], ['M01.060.116'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.754.864.696'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['F01.145.722'], ['F01.145.802'], ['C25.775'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cost-effectiveness of incisional negative pressure wound therapy compared with standard care after caesarean section in obese women: a trial-based economic evaluation. | OBJECTIVE: To evaluate the cost-effectiveness of incisional negative pressure wound therapy (iNPWT) in preventing surgical site infection in obese women after caesarean section.DESIGN: A cost-effectiveness analysis conducted alongside a clinical trial.SETTING: Five obstetric departments in Denmark.POPULATION: Women wit... | ['Adult', 'Bandages', 'Cesarean Section', 'Cost-Benefit Analysis', 'Denmark', 'Female', 'Humans', 'Negative-Pressure Wound Therapy', 'Obesity', 'Pregnancy', 'Pregnancy Complications', 'Quality-Adjusted Life Years', 'Standard of Care', 'Surgical Wound Infection', 'Treatment Outcome'] | 30,507,022 | [['M01.060.116'], ['E07.101'], ['E04.520.252.500'], ['N03.219.151.125'], ['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.309.610', 'E04.237.444', 'E04.987.550'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['G08.686.784.76... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mechanistics of formation and ultrastructural evaluation of hepatocyte spheroids. | Freshly harvested rat hepatocytes form spheroids on uncoated positively charged polystyrene surfaces. Time lapse microscopy revealed that cell movement and reorganization were involved in spheroid formation. Ultrastructural evaluation using scanning and transmission electron microscopy indicated polarized cellular morp... | ['Albumins', 'Animals', 'Cytochrome P-450 Enzyme System', 'Liver', 'Liver, Artificial', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Spheroids, Cellular'] | 8,727,043 | [['D12.776.034'], ['B01.050'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A03.620'], ['E07.858.082.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A11.251.800']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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