Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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A CASE OF NEUROFIBROMATOSIS TYPE 2 WITH UNUSUAL CLINICAL FEATURES. | PURPOSE: To report a case of a neurofibromatosis Type 2 with unusual clinical features.METHODS: Observational clinical case report.RESULTS: A 22-year-old woman was referred with bilateral blurred vision and macular "scars." Ocular examination revealed bilateral posterior subcapsular and cortical cataract, optic disk sw... | ['Brain', 'Epiretinal Membrane', 'Female', 'Fluorescein Angiography', 'Fundus Oculi', 'Humans', 'Magnetic Resonance Imaging', 'Neurofibromatosis 2', 'Optic Disk', 'Retina', 'Tomography, Optical Coherence', 'Tomography, X-Ray Computed', 'Young Adult'] | 28,834,919 | [['A08.186.211'], ['C11.768.328'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.557.465.625.650.595.610.500', 'C04.557.580.600.580.590.655', 'C04.557.580.600.610.595.610.500', 'C04.700.631.655', 'C09.218.807.800.675.500'... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Patients with primary localized high-grade sarcomas of the digestive tract excluding GIST : a retrospective study from the French sarcoma group. | INTRODUCTION : The natural history of localized high-grade sarcomas of the digestive tract (SDT) excluding GIST has been rarely considered owing to their low incidence and heterogeneity. We describe the histoclinical characteristics of SDT and correlate them with patients' outcomes.METHODS: We retrospectively collected... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Disease Progression', 'Europe', 'Female', 'France', 'Gastrointestinal Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Retrospective Studies', 'Sarcoma', 'Survival Rate'] | 29,560,643 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['C23.550.291.656'], ['Z01.542'], ['Z01.542.286'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.612'], ['E05.318.372.500.500.500', 'E05.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Antiplasmodial activities of homogentisic acid derivative protein kinase inhibitors isolated from a Vanuatu marine sponge Pseudoceratina sp. | As part of our search for new antimalarial drugs in South Pacific marine sponges, we have looked for inhibitors of Pfnek-1, a specific protein kinase of Plasmodium falciparum. On the basis of promising activity in a preliminary screening, the ethanolic crude extract of a new species of Pseudoceratina collected in Vanua... | ['Animals', 'Anti-Bacterial Agents', 'Antimalarials', 'Enzyme Assays', 'Homogentisic Acid', 'Plasmodium falciparum', 'Porifera', 'Protein Kinase Inhibitors', 'Vanuatu'] | 20,098,604 | [['B01.050'], ['D27.505.954.122.085'], ['D27.505.954.122.250.100.085'], ['E05.196.427'], ['D02.241.223.601.421'], ['B01.043.075.380.611.561'], ['B01.050.500.802'], ['D27.505.519.389.755'], ['Z01.639.760.590.736']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Who reports sexual function problems? Empirical evidence from Britain's 2000 National Survey of Sexual Attitudes and Lifestyles. | OBJECTIVE: To identify sociodemographic, sexual, and health behavioural and attitudinal factors associated with reporting sexual function problems.METHODS: A probability sample survey of 11 161 men and women aged 16-44 years resident in Britain in 2000. Data collected by a combination of computer assisted face to face ... | ['Adolescent', 'Adult', 'Attitude to Health', 'Female', 'Humans', 'Male', 'Patient Acceptance of Health Care', 'Self Disclosure', 'Sexual Behavior', 'Sexual Dysfunction, Physiological', 'Sexual Partners', 'United Kingdom'] | 16,199,738 | [['M01.060.057'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['F01.752.747.792.662'], ['F01.145.802'], ['C12.294.644', 'C13.351.500.665'], ['M01.778'], ['Z01.542.363']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cardiorespiratory control by carotid chemoreceptors during experimental dives in the seal. | The diving responses of apnea and bradycardia, produced experimentally by immersing the face in water, were successfully elicited in the harbor seal Phoca vitulina anesthetized with urethan. The role of the carotid body chemoreceptors in the production of the diving bradycardia was studied in isolated carotid sinus-bod... | ['Animals', 'Blood Pressure', 'Caniformia', 'Carotid Body', 'Diving', 'Female', 'Heart Rate', 'Hemodynamics', 'Male', 'Respiration', 'Seals, Earless', 'Trachea'] | 860,766 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.750.250'], ['A08.675.650.915.500.600.150', 'A08.800.950.500.600.150', 'A11.671.650.915.500.600.150'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['G09.772.705'], ['B0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Treatment of pruritus in a palliative care patient with low-dose paroxetine: a case report. | BACKGROUND: Pruritus is a distressing symptom seen in palliative care. There is limited high-quality evidence of pharmaceutical treatments for pruritus in palliative care, including the use of paroxetine.CASE PRESENTATION: I present a case of a 70-year-old caucasian woman with metastatic ovarian cancer who presented wi... | ['Aged', 'Cholestasis', 'Cytochrome P-450 CYP2D6 Inhibitors', 'Female', 'Humans', 'Liver Neoplasms', 'Ovarian Neoplasms', 'Palliative Care', 'Paroxetine', 'Pruritus', 'Treatment Outcome'] | 28,965,488 | [['M01.060.116.100'], ['C06.130.120.135'], ['D27.505.389.500.368', 'D27.505.519.389.335.368'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E02.760.666', 'N02... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Varices of the common bile duct as a surgical hazard. | In the case of a 78-year-old woman with three common duct stones is reported. The most striking finding at operation, was extensive varices of the common duct. There was no evidence of varices elsewhere nor of an arteriovenous fistula. The varices are assumed to be idiopathic or a unique manifestation of a chronic chol... | ['Aged', 'Biliary Tract Diseases', 'Common Bile Duct', 'Female', 'Gallstones', 'Hemorrhage', 'Humans', 'Varicose Veins'] | 911,102 | [['M01.060.116.100'], ['C06.130'], ['A03.159.183.079.300'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.927']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pharmacokinetics of cisplatin and relation to nephrotoxicity in paediatric patients. | BACKGROUND: Cisplatin is a highly effective and frequently used drug in the chemotherapy of solid tumours in children, but only limited data are available on the pharmacokinetics of cisplatin and its associated nephrotoxicity in paediatric patients.METHODS: We investigated the pharmacokinetics of free platinum (Pt) in ... | ['Adolescent', 'Adult', 'Albuminuria', 'Antineoplastic Agents', 'Area Under Curve', 'Biomarkers', 'Child', 'Child, Preschool', 'Cisplatin', 'Creatinine', 'Drug Administration Schedule', 'Female', 'Half-Life', 'Humans', 'Infusions, Intravenous', 'Kidney', 'Kidney Diseases', 'Male', 'Membrane Glycoproteins', 'Neoplasms',... | 11,599,657 | [['M01.060.057'], ['M01.060.116'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D27.505.954.248'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D03.383.129... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Macroconidial development and germination in Trichophyton mentagrophytes. | Trichophyton Mentagrophytes was investigated for macroconidial development with particular emphasis on the conidial ageing by light and scanning electron microscopy. Macroconidial germination was also studied under various conditions. Sabouraud glucose agar supplemented with 3% NaCl was used to enhance production of ma... | ['Sodium Chloride', 'Temperature', 'Trichophyton'] | 3,339,260 | [['D01.210.450.150.875', 'D01.857.650'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['B01.300.381.928']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Habituation of premonitory sensations during exposure and response prevention treatment in Tourette's syndrome. | Exposure to premonitory sensations and response prevention of tics (ER) has been shown to be a promising new treatment for Tourette's syndrome (TS). The present study tested the hypothesis that habituation to unpleasant premonitory sensations associated with the tic is an underlying mechanism of change in ER. Patients ... | ['Adolescent', 'Adult', 'Child', 'Female', 'Habituation, Psychophysiologic', 'Humans', 'Male', 'Middle Aged', 'Sensation', 'Tics', 'Tourette Syndrome'] | 18,285,507 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['F02.463.425.393', 'F02.830.422', 'G11.561.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.830.816', 'G11.561.790'], ['C10.597.350.700', 'C23.888.592.350.700'], ['C10.228.140.079.898', 'C10.228.662.825.800', 'C10.574.500.850', 'C16.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Repeated injections of nicergoline increase the nerve growth factor level in the aged rat brain. | We studied whether nicergoline, clinically active in chronic cerebrovascular insufficiency, influences nerve growth factor (NGF) levels in the rat brain. In young Fischer rats, repeated intraperitoneal injections of nicergoline (0.3 and 1.0 mg/kg body weight) did not show any effects on frontal NGF contents determined ... | ['Aging', 'Animals', 'Brain', 'Injections, Intraperitoneal', 'Male', 'Nerve Growth Factors', 'Nicergoline', 'Nootropic Agents', 'Rats', 'Rats, Inbred F344'] | 9,593,228 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['E02.319.267.530.490'], ['D12.644.276.860', 'D12.776.467.860', 'D12.776.631.600', 'D23.529.850'], ['D03.132.327.287.730', 'D03.633.400.439.730'], ['D27.505.954.427.637'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.200', 'B01.050.150.900.649.31... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A quantitative light microscopic analysis and ultrastructural description of cholecystokinin-like immunoreactivity in the spinal trigeminal nucleus of the rat. | The spinal trigeminal nucleus is involved in orofacial sensory transmission. Cholecystokinin octapeptide has been identified in axons in this nucleus and appears to play a role in the transmission of orofacial sensation from the trigeminal ganglia to the spinal trigeminal nucleus. Although cholecystokinin has been repo... | ['Animals', 'Endorphins', 'Histocytochemistry', 'Immunochemistry', 'Male', 'Microscopy, Electron', 'Rats', 'Rats, Inbred Strains', 'Receptors, Opioid', 'Sincalide', 'Trigeminal Nucleus, Spinal'] | 3,035,422 | [['B01.050'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['H01.158.201.486', 'H01.181.122.605', 'H02.403.044.500'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Desmopressin 120 mcg, 180 mcg, 240 mcg: The right treatment for the right patient. | BACKGROUND: The first-line drug therapy for patients with nocturnal enuresis (NE) associated with nocturnal polyuria and normal bladder function is desmopressin (dDAVP).OBJECTIVE: To evaluate if increasing dose of oral desmopressin lyophilisate (MELT) can improve response rates to dDAVP and is useful in enuretic childr... | ['Administration, Oral', 'Adolescent', 'Child', 'Child, Preschool', 'Deamino Arginine Vasopressin', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Male', 'Nocturnal Enuresis', 'Renal Agents', 'Treatment Outcome'] | 29,974,730 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['D06.472.699.631.692.781.100.250', 'D12.644.400.900.100.250', 'D12.644.456.925.100.250', 'D12.644.548.691.692.781.100.250', 'D12.776.631.650.937.100.250'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Solving Tomorrow's Problems Today? Daily Anticipatory Coping and Reactivity to Daily Stressors. | OBJECTIVES: The present study examined the day-to-day fluctuation of state-like anticipatory coping (coping employed prior to stressors) and how these coping processes relate to important outcomes for older adults (i.e., physical health, affect, memory failures).METHOD: Forty-three older adults aged 60-96 (M = 74.65, S... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Affect', 'Aged', 'Aged, 80 and over', 'Female', 'Health Status', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Resilience, Psychological', 'Self Efficacy', 'Stress, Psychological'] | 25,681,090 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['F01.470.047'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['F02.940'], ['F01.752.747.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Accumulation of phenylpropanoid derivatives in chitosan-induced cell suspension culture of Cocos nucifera. | Chitosan-induced elicitation responses of dark-incubated Cocos nucifera (coconut) endosperm cell suspension cultures led to the rapid formation of phenylpropanoid derivatives, which essentially mimics the defense-induced biochemical changes in coconut palm as observed under in vivo conditions. An enhanced accumulation ... | ['Aldehyde Oxidoreductases', 'Cell Wall', 'Cells, Cultured', 'Chitosan', 'Cocos', 'Enzyme Inhibitors', 'Hydroxybenzoates', 'Peroxidase', 'Phenols', 'Phenylalanine Ammonia-Lyase', 'Time Factors'] | 18,448,193 | [['D08.811.682.657.163'], ['A11.284.183'], ['A11.251'], ['D05.750.078.139.500', 'D09.698.211.500'], ['B01.650.940.800.575.912.250.093.211'], ['D27.505.519.389'], ['D02.241.223.100.300', 'D02.241.511.390', 'D02.455.426.559.389.127.281', 'D02.455.426.559.389.657.410'], ['D08.811.682.732.700'], ['D02.455.426.559.389.657']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Side effects in excimer corneal surgery. DNA damage as a result of 193 nm excimer laser radiation. | UV radiation is known to cause actinic damage to the DNA. Excimer laser light, possibly used for keratorefractive surgery, should not produce this damage, as the penetration depth is far less than the diameter of a cell. However, photoreactivation experiments with yeast cells show a significant amount of DNA repair aft... | ['Cell Line', 'Cornea', 'DNA Damage', 'Dose-Response Relationship, Radiation', 'Laser Therapy', 'Radiation Injuries', 'Yeasts'] | 3,402,750 | [['A11.251.210'], ['A09.371.060.217'], ['G05.200'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E02.594', 'E04.014.520'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['B01.300.930']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cortical surface characteristics among offspring of schizophrenia subjects. | BACKGROUND: A systematic study of cortical surface parameters in adolescent offspring of schizophrenia subjects before clinical manifestation could clarify neurodevelopmental antecedents of increased genetic risk. We examined these measures obtained on structural magnetic resonance imaging (MRI) scans at baseline and o... | ['Adolescent', 'Cerebral Cortex', 'Child', 'Child of Impaired Parents', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Male', 'Schizophrenia', 'Young Adult'] | 19,962,858 | [['M01.060.057'], ['A08.186.211.200.885.287.500'], ['M01.060.406'], ['M01.106'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E01.370.350.825.500'], ['F03.700.750'], ['M01.060.116.815... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Pathology of colonic polyps]. | Recent developments in the field of polyps of the colon are discussed. The WHO classification represents a definite improvement. Apart from standardization, non-neoplastic polypoid changes of varying etiology and hamartomatous polyps are clearly distinguished from neoplastic, non-malignant adenomas. The various changes... | ['Adenoma', 'Carcinoma', 'Colon', 'Colonic Neoplasms', 'Diagnosis, Differential', 'Humans', 'Intestinal Neoplasms', 'Intestinal Polyps', 'World Health Organization'] | 675,194 | [['C04.557.470.035'], ['C04.557.470.200'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411', 'C... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biologic activity of synthetic analogues of C5a anaphylatoxin. | The C activation fragment C5a is the most potent plasma-derived chemotactic factor known. This humoral factor induces both neutrophil and macrophage activation at low nanomolar concentrations. We have synthesized a series of C-terminal C5a analogues that exhibit all of the characteristic biologic activities of C5a. The... | ['Amino Acid Sequence', 'Animals', 'Capillary Permeability', 'Chemotaxis, Leukocyte', 'Complement C5a', 'Guinea Pigs', 'Humans', 'Mice', 'Molecular Sequence Data', 'Muscle Contraction', 'Peptide Fragments', 'Platelet Aggregation', 'Structure-Activity Relationship'] | 1,578,141 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G03.143.330', 'G09.330.165'], ['G04.198.424.233'], ['D12.776.124.486.274.024.270', 'D12.776.124.486.274.450.250'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Factors affecting image acquisition during scanning laser polarimetry. | BACKGROUND AND OBJECTIVE: To illustrate artifacts that may be encountered during measurement of the peripapillary retinal nerve fiber layer (RNFL) using scanning laser polarimetry (SLP).PATIENTS AND METHODS: A total of 426 patients with a variety of ocular diagnoses underwent RNFL measurements using SLP from June 1996 ... | ['Aged', 'Artifacts', 'Diagnostic Techniques, Ophthalmological', 'Eye Diseases', 'Female', 'Humans', 'Lasers', 'Male', 'Middle Aged', 'Nerve Fibers', 'Optic Disk', 'Retina'] | 9,674,004 | [['M01.060.116.100'], ['E05.047'], ['E01.370.380'], ['C11'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490', 'E07.710.520'], ['M01.060.116.630'], ['A08.675.542', 'A11.671.501'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['A09.371.729']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of acetyl strophanthidin on duration of atrial fibrillation in the neurally-intact and blockaded dog. | Although the inotropic and dromotropic effects of cardiac glycosides in atrial fibrillation (AF) are well recognized, their action on AF itself is not clear. Accordingly, to determine whether cardiac glycosides prolong AF, the duration of electrically induced AF, atrioventricular conduction, and left ventricular functi... | ['Animals', 'Atrial Fibrillation', 'Dogs', 'Electric Stimulation', 'Nerve Block', 'Strophanthidin'] | 3,154,634 | [['B01.050'], ['C14.280.067.198', 'C23.550.073.198'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.723.402'], ['E03.155.086.711', 'E04.525.210.550'], ['D04.210.500.155.580.130.750.800']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Reversible dementia due to valproic acid therapy]. | A progressive dementia syndrome (DSM IV) with frontal-subcortical features developed in a 72-year-old woman during valproate therapy (Depakine). Discontinuation of valproate resulted in complete recovery. Drugs are a common cause of reversible dementia. The association of dementia with valproate therapy is rare. Featur... | ['Aged', 'Anticonvulsants', 'Dementia', 'Epilepsy, Tonic-Clonic', 'Female', 'Frontal Lobe', 'Humans', 'Valproic Acid'] | 9,157,301 | [['M01.060.116.100'], ['D27.505.954.427.080'], ['C10.228.140.380', 'F03.615.400'], ['C10.228.140.490.375.290'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.944.509.900', 'D10.251.400.895.593.900']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transfer of the scorpion toxin receptor to an insensitive potassium channel. | Voltage-dependent potassium channels belong to a family of structurally related cation channels that underlie the electrical activity of excitable cells. Many potassium channels are blocked with high affinity by scorpion toxins, whereas others are completely insensitive. We transferred toxin sensitivity from the highly... | ['Amino Acid Sequence', 'Animals', 'Female', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Oocytes', 'Potassium Channels', 'Recombinant Fusion Proteins', 'Recombinant Proteins', 'Sequence Homology', 'Sodium Channels', 'Structure-Activity Relationship', 'Xenopus'] | 7,946,339 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['A05.360.490.690.680', 'A11.497.497.600'], ['D12.776.157.530.400.600', 'D12.776.543.550.450.750', 'D12.776.543.585.400.750'], ['D12.776.828.300'], ['D12.776.828'], ['G02.111.810', 'G05.810'], ['D12.776.157.530.400.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Leukemia inhibitory factor in long-term adherent layer cultures: increased levels of bioactive protein in leukemia and modulation by IL-4, IL-1 beta, and TNF-alpha. | In the current study, we used a monoclonal antibody-based enzyme-linked immunosorbent assay and bioassay to assess leukemia inhibitory factor (LIF) protein levels, activity, and function in supernatants of 59 adherent layers derived from acute and chronic myelogenous leukemia, myelodysplastic syndrome, and hairy cell l... | ['Blast Crisis', 'Bone Marrow', 'Cell Adhesion', 'Cell Line', 'Cells, Cultured', 'Growth Inhibitors', 'Humans', 'Interleukin-1', 'Interleukin-4', 'Interleukin-6', 'Leukemia', 'Leukemia Inhibitory Factor', 'Leukemia, Hairy Cell', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Leukemia, Myeloid, Acute', 'Lymphokine... | 8,137,298 | [['C04.557.337.539.250.100', 'C04.697.098.500.110', 'C15.378.190.636.370.100', 'C23.550.727.098.500.110'], ['A15.382.216'], ['G04.022'], ['A11.251.210'], ['A11.251'], ['D27.505.696.377.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Precipitin and mitogenic behavior of dimeric and tetrameric concanavalin A. | The results of double diffusion and quantitative precipitin tests show that in contrast to the concanavalin A tetramer, the dimer is incapable of precipitating glycogen. The results support previous work suggesting that dimers composed of two fragmented monomer units possess only one binding site for carbohydrate (McKe... | ['Animals', 'Chemical Precipitation', 'Concanavalin A', 'Glycogen', 'Lymphocyte Activation', 'Mice', 'Mitogens', 'Protein Conformation', 'Structure-Activity Relationship'] | 976,313 | [['B01.050'], ['E05.196.150', 'G02.159'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D05.750.078.562.388', 'D09.698.365.388'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.505.519.593.624'], ['G02.111.570.820.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interferon-gamma potentiates the antiviral activity and the expression of interferon-stimulated genes induced by interferon-alpha in U937 cells. | Binding of type I interferon (IFN-alpha/beta) to specific receptors results in the rapid transcriptional activation, independent of protein synthesis, of IFN-alpha-stimulated genes (ISGs) in human fibroblasts and HeLa and Daudi cell lines. The binding of ISGF3 (IFN-stimulated gene factor 3) to the conserved IFN-stimula... | ['Cell Line', 'Cycloheximide', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Humans', 'Interferon-Stimulated Gene Factor 3', 'Interferon-Stimulated Gene Factor 3, alpha Subunit', 'Interferon-Stimulated Gene Factor 3, gamma Subunit', 'Interferon-alpha', 'Interferon-gamma', 'Monocytes', 'Radioligand Assay', 'Tra... | 1,315,834 | [['A11.251.210'], ['D03.383.621.808.240'], ['D12.776.260'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.024.303', 'D12.776.157.057.061', 'D12.776.260.513', 'D12.776.476.024.386', 'D12.776.930.354'], ['D12.644.360.024.303.500', 'D12.776.157.057.061.500', 'D12.776.260.513.249', 'D12.776.47... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular analysis of the gonadotropin-releasing hormone receptor in patients with polycystic ovary syndrome. | OBJECTIVE: To determine whether a mutation in the GnRH receptor gene is responsible for polycystic ovary syndrome (PCOS).DESIGN: Molecular analysis of human genomic DNA.SETTING: Academic research environment.PATIENT(S): Eighty patients with PCOS.INTERVENTION(S): Extraction and polymerase chain reaction (PCR) analysis o... | ['Adolescent', 'Adult', 'DNA Mutational Analysis', 'Exons', 'Female', 'Humans', 'Open Reading Frames', 'Polycystic Ovary Syndrome', 'Polymerase Chain Reaction', 'Receptors, LHRH'] | 10,439,012 | [['M01.060.057'], ['M01.060.116'], ['E05.393.760.700.300'], ['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['C04.182.612.765', 'C13.351.500.056.630.580.765', 'C19.391.630.580.765'], ['E05.393.620.500'], ['D12.776.543.750.695.410'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intravesical migration of an intrauterine contraceptive device complicated by bladder stone: a report of six cases. | Intrauterine contraceptive device is the most popular method of reversible contraception in developing countries due to its efficiency and low cost. However, this device is often inserted by paramedics of variable skills, and follow-up evaluations are irregular or absent which can be the source of major complications. ... | ['Adult', 'Cystoscopy', 'Device Removal', 'Female', 'Foreign-Body Migration', 'Humans', 'Intrauterine Devices', 'Lithotripsy', 'Treatment Outcome', 'Urinary Bladder', 'Urinary Bladder Calculi'] | 16,941,071 | [['M01.060.116'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['E04.199'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.190.250.510'], ['E02.600', 'E04.943.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['A05.810.890'], ['C12.77... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glucose absorption and production following oral glucose: comparison of compartmental and arteriovenous-difference methods. | Both whole-body models and the regional arteriovenous (AV)-difference method have been used to calculate systemic glucose rates of appearance (Ras) under non-steady-state conditions. Although whole-body models have been experimentally validated in the dog, direct comparison of the whole-body and regional-balance approa... | ['Administration, Oral', 'Blood Glucose', 'Brachial Artery', 'Glucose', 'Hepatic Veins', 'Humans', 'Kinetics', 'Models, Biological'] | 7,968,597 | [['E02.319.267.100'], ['D09.947.875.359.448.500'], ['A07.015.114.139'], ['D09.947.875.359.448'], ['A07.015.908.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.599.395']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis. | Based largely on studies in xenograft models, lipocalin-2 (Lcn2) has been implicated in the progression of multiple types of human tumors, including breast cancer. Here we examine the role of Lcn2 in mammary tumorigenesis and lung metastasis using an in vivo molecular genetics approach. We crossed a well-characterized ... | ['Acute-Phase Proteins', 'Animals', 'Blotting, Western', 'Crosses, Genetic', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Histological Techniques', 'Lipocalin-2', 'Lipocalins', 'Lung Neoplasms', 'Mammary Neoplasms, Animal', 'Matrix Metalloproteinase 9', 'Mice', 'Mice, Transgenic', 'Neoplasm Metastasis', 'Oncogene ... | 20,133,630 | [['D12.776.124.050'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.393.281'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.750', 'E05.200.750'], ['D12.776.124.050.475', 'D12.776.157.469.325', 'D12.776.624.664.700.123'], ['D12.776.157.46... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Requirements for dynamical differential phase contrast x-ray imaging with a laboratory source. | X-ray phase contrast enables weakly-attenuating structures to be imaged, with bright synchrotron sources adding the ability to capture time sequences and analyse sample dynamics. Here, we describe the translation of dynamical differential phase contrast imaging from the synchrotron to a compact x-ray source, in order t... | ['Laboratories', 'Molecular Imaging', 'Phantoms, Imaging', 'Signal-To-Noise Ratio', 'Synchrotrons', 'X-Rays'] | 27,893,458 | [['J03.520', 'N02.278.487'], ['E01.370.350.557', 'E05.601.555'], ['E07.671'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750'], ['E07.710.680.700'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.75... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Single stage treatment of diabetic calcaneal osteomyelitis with an absorbable gentamicin-loaded calcium sulphate/hydroxyapatite biocomposite: The Silo technique. | BACKGROUND: Chronic osteomyelitis necessities appropriate infected bone and soft tissue excision. The authors describe the Silo surgical technique for the treatment of calcaneal osteomyelitis using a new antibiotic-loaded absorbable calcium sulphate/hydroxyapatite biocomposite.METHODS: The Silo method involves debridem... | ['Absorbable Implants', 'Aged', 'Aged, 80 and over', 'Calcaneus', 'Calcium Sulfate', 'Chronic Disease', 'Combined Modality Therapy', 'Databases, Factual', 'Debridement', 'Diabetic Foot', 'Drug Delivery Systems', 'Durapatite', 'Female', 'Gentamicins', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Osteo... | 29,278,835 | [['E07.695.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.835.232.043.300.710.300'], ['D01.146.375', 'D01.578.215', 'D01.875.800.800.850.125'], ['C23.550.291.500'], ['E02.186'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.176'], ['C14.907.320.191', 'C17.800.893.592.450.200', 'C19.246.099.500.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Exposure assessment of phthalates in French pregnant women: results of the ELFE pilot study. | The ubiquitous use of phthalate esters in plastics, building material, medical devices, personal care products and food packaging materials results in a widespread exposure of general population. This study reports measurement of urinary concentration of phthalate metabolites in France and provides a first assessment o... | ['Environmental Monitoring', 'Environmental Pollutants', 'Female', 'France', 'Humans', 'Models, Biological', 'Phthalic Acids', 'Pilot Projects', 'Pregnancy'] | 23,394,847 | [['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['D02.241.223.805'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['G08.686.784.769']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Angiocentric Centrofacial Lymphoma as a Challenging Diagnosis in an Elderly Man. | BACKGROUND Angiocentric centrofacial lymphomas, now known as nasal-type extranodal natural killer T-cell lymphomas, are neoplasms of highly destructive characteristics that mainly affect the nasal cavity and palate. The most frequent clinical presentation includes fever, weight loss, nasal obstruction, epistaxis, nasal... | ['Aged', 'Epstein-Barr Virus Infections', 'Fever', 'Humans', 'Hyperhidrosis', 'Lymphoma, Extranodal NK-T-Cell', 'Male', 'Nasal Obstruction', 'Nose Neoplasms'] | 30,926,768 | [['M01.060.116.100'], ['C01.925.256.466.313', 'C01.925.928.313'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.946.350'], ['C04.557.386.480.750.199'], ['C08.460.525', 'C08.618.846.185.525', 'C09.603.525'], ['C04.588.149.721.600', 'C04.588.443.665.650', 'C05.116.231.754.600', 'C08.460.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Triaging patients to the ICU: a pilot study of factors influencing admission decisions and patient outcomes. | OBJECTIVE: To assess the appropriateness of ICU triage decisions. DESIGN. Prospective descriptive single-center study.SETTING: Ten-bed, medical-surgical ICU in an acute-care 460-bed, tertiary care hospital.PATIENTS: All patients triaged for admission were entered prospectively.INTERVENTIONS: None.MEASUREMENTS AND MAIN ... | ['Decision Making', 'Female', 'Hospital Mortality', 'Humans', 'Intensive Care Units', 'Logistic Models', 'Male', 'Middle Aged', 'Patient Admission', 'Pilot Projects', 'Probability', 'Triage'] | 12,677,368 | [['F02.463.785.373'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sleep duration and excess heart age among US adults. | OBJECTIVES: Insufficient sleep negatively impacts the cardiovascular system. No study has examined the association between sleep duration and heart age (person's predicted vascular age based on cardiovascular disease [CVD] risk profile). This study examines association between sleep duration and excess heart age (EHA; ... | ['Adult', 'Aged', 'Cardiovascular Diseases', 'Cross-Sectional Studies', 'Female', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Sleep', 'Sleep Deprivation', 'Time Factors', 'United States'] | 30,241,660 | [['M01.060.116'], ['M01.060.116.100'], ['C14'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A finite element model of cell-matrix interactions to study the differential effect of scaffold composition on chondrogenic response to mechanical stimulation. | Mechanically induced cell deformations have been shown to influence chondrocyte response in 3D culture. However, the relationship between the mechanical stimulation and cell response is not yet fully understood. In this study a finite element model was developed to investigate cell-matrix interactions under unconfined ... | ['Biomechanical Phenomena', 'Cell Size', 'Chondrocytes', 'Chondrogenesis', 'Extracellular Matrix', 'Finite Element Analysis', 'Humans', 'Hydrogels', 'Mechanical Phenomena', 'Mechanotransduction, Cellular', 'Polyethylene Glycols', 'Tissue Engineering', 'Tissue Scaffolds'] | 21,428,684 | [['G01.154.090', 'G01.374.089'], ['G04.325'], ['A11.329.171'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['A11.284.295.310'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375', 'D26.255.165.320.375'], ['G01.374'], ['G01.154.090.500', 'G02.111.820.580', 'G04.835.580'], ['D02.033.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Design, synthesis, and evaluation of the anticancer activity of 2-amino-aryl-7-aryl-benzoxazole compounds. | A series of 2-amino-aryl-7-aryl-benzoxazole derivatives have been designed, synthesized, and evaluated as anticancer agents. Fourteen of the compounds exhibited cytotoxic effects toward human A549 lung cancer cells. We found 12l was the most potent with an EC50 of 0.4 ìm, equivalent to the anticancer drug doxorubicin, ... | ['Animals', 'Antineoplastic Agents', 'Benzoxazoles', 'Cell Line, Tumor', 'Chlorocebus aethiops', 'Drug Design', 'Drug Screening Assays, Antitumor', 'Humans', 'Janus Kinase 2', 'Lung Neoplasms', 'Molecular Docking Simulation', 'Neoplasms', 'Protein Kinase Inhibitors', 'Structure-Activity Relationship', 'Vero Cells'] | 28,544,428 | [['B01.050'], ['D27.505.954.248'], ['D03.633.100.221'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Distress and self-soothing bedtime behaviors in hospitalized children with non-rooming-in parents. | The nature of behaviors during sleep onset latency (SOL) at night bedtime was studied in a group of 40 hospitalized children ages 3 to 8 years whose parents did not room-in. Research questions were: (a) What is the nature of behaviors during sleep onset latency of young children whose parents do not room-in? and (b) Ho... | ['Adaptation, Psychological', 'African Americans', 'Anxiety, Separation', 'Child', 'Child, Hospitalized', 'Child, Preschool', 'Female', 'Humans', 'Infant Care', 'Infant, Newborn', 'Male', 'Parents', 'Rooming-in Care', 'Sleep', 'Sleep Deprivation', 'Sleep Stages', 'Socioeconomic Factors'] | 3,068,426 | [['F01.058'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F03.080.300', 'F03.625.047'], ['M01.060.406'], ['M01.643.259'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.088.120'], ['M01.060.703.520'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['N02.421.088.120.240... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Unraveling the protein targets of vancomycin in living S. aureus and E. faecalis cells. | Vancomycin is a potent glycopeptide antibiotic that has evolved to specifically bind to the D-Ala-D-Ala dipeptide termini of nascent peptidoglycans. Although this mode of action is well established, several studies indicate that vancomycin and analogues exploit noncanonical target sites. In order to address all vancomy... | ['ATP-Binding Cassette Transporters', 'Anti-Bacterial Agents', 'Binding Sites', 'Dose-Response Relationship, Drug', 'Enterococcus faecalis', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Photoaffinity Labels', 'Proteomics', 'Staphylococcus aureus', 'Stereoisomerism', 'Structure-Activity Relationship', 'Vancomy... | 21,736,328 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954.122.085'], ['G02.111.570.120'], ['G07.690.773.875', 'G07.690.936.500'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G02.111.570', 'G02... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Diversity in the magnitude of hind limb unloading occurs with similar forms of lameness in dairy cows. | The objective of the study was to evaluate the relationship of veterinary clinical assessments of lameness to probability estimates of lameness predicted from vertical kinetic measures. We hypothesized that algorithm-derived probability estimates of lameness would accurately reflect vertical measures in lame limbs even... | ['Algorithms', 'Animals', 'Biomechanical Phenomena', 'Cattle', 'Cattle Diseases', 'Female', 'Hindlimb', 'Lameness, Animal', 'Pain', 'Pain Measurement'] | 21,385,514 | [['G17.035', 'L01.224.050'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A13.473'], ['C22.510'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E01.370.600.550.324']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma. | PURPOSE: To identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the nonmalignant fallopian tube epithelium (FTE) of BRCA1/2 mutation carriers, given recent evidence implicating the distal FTE as a common source for SerCa.EXPERIMENTAL DESIGN: We obtained and compa... | ['Adult', 'Cystadenocarcinoma, Serous', 'DNA Mutational Analysis', 'Epithelium', 'Fallopian Tube Neoplasms', 'Fallopian Tubes', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Genes, BRCA1', 'Genetic Predisposition to Disease', 'Humans', 'Middle Aged', 'Mutation', 'Ovarian Neoplasms'] | 18,593,983 | [['M01.060.116'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['E05.393.760.700.300'], ['A10.272'], ['C04.588.945.418.365', 'C13.351.500.056.390.390', 'C13.351.937.418.365'], ['A05.360.319.114.373', 'A13.706.500'], ['E05.393.332'], ['G05.308.370'], ['G05.360.340.024.340.375.249.100', 'G05.360.340.024.34... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of acupressure on nausea and vomiting during pregnancy. | UNLABELLED: This paper sought to determine the efficacy of acupressure application in pregnant women suffering from nausea, with or without associated vomiting, who were unable to receive conventional medication for these symptoms. Sampling consisted of pregnant women complaining of nausea with or without vomiting. The... | ['Acupressure', 'Acupuncture Points', 'Adult', 'Female', 'Hospitals, Maternity', 'Humans', 'Morning Sickness', 'Nausea', 'Pregnancy', 'Treatment Outcome', 'Turkey', 'Wrist'] | 18,243,942 | [['E02.190.599.750.500', 'E02.779.867.880.500', 'E02.831.535.867.880.500'], ['E02.190.044.555.035'], ['M01.060.116'], ['N02.278.421.556.366'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.407', 'C23.888.821.937.049'], ['C23.888.821.712'], ['G08.686.784.769'], ['E01.789.800', 'N04.761.559.590.800', 'N05.71... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sodium needs of infants and children with ileostomy. | We studied gastrointestinal tract excretion of sodium and water in seven infants with an abdominal ileostomy (group 1) and three children with a Soave ileoendorectal pull-through (group 2). When the daily sodium intake of the patients was 5 to 7 mEq/kg (twice usual maintenance), average daily ileal sodium losses were 2... | ['Aldosterone', 'Body Water', 'Child', 'Child, Preschool', 'Feces', 'Food, Fortified', 'Humans', 'Ileostomy', 'Infant', 'Infant, Newborn', 'Intestinal Perforation', 'Male', 'Nutritional Requirements', 'Peritonitis', 'Postoperative Complications', 'Rectum', 'Renin', 'Sodium'] | 6,339,704 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['A12.207.200'], ['M01.060.406'], ['M01.060.406.448'], ['A12.459'], ['G07.203.300.515', 'J02.500.515'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['M01.060.703'], ['M01.060.703.520'], ['C06.405.469.557'], ['G07.2... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Ambulatory blood pressure variations relative to sitting or standing position in renal transplant patients. | OBJECTIVE: High blood pressure is almost constant in renal transplant patients for whom dysautonomia is frequently described. The main objective of this study was to analyse the variations in blood pressure and heart rate recorded by ambulatory measurement during changes in position in renal transplant patients.METHODS... | ['Adult', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Circadian Rhythm', 'Female', 'Heart Rate', 'Humans', 'Hypertension, Renal', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Posture', 'Shy-Drager Syndrome'] | 15,812,257 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['G07.180.562.190'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['E02.870.500', 'E04.936.450.485'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intrahepatic biliary-intestinal bypass in malignant jaundice. | There is still dispute as to the best treatment for obstructive jaundice of malignant origin when the bile ducts are blocked high in the porta hepatis. Intrahepatic duct-to-jejunal anastomoses provide a surgical solution which frees the patient from the need to wear external appliances. A series of eight patients havin... | ['Aged', 'Bile Ducts, Intrahepatic', 'Biliary Tract Neoplasms', 'Bilirubin', 'Cholestasis', 'Female', 'Humans', 'Jejunum', 'Length of Stay', 'Male', 'Middle Aged', 'Palliative Care', 'Prognosis', 'Time Factors'] | 2,424,418 | [['M01.060.116.100'], ['A03.159.183.158', 'A03.620.150'], ['C04.588.274.120', 'C06.130.320', 'C06.301.120'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['C06.130.120.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.500', 'A03.556.249.75... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serum concentrations of prolactin, oestrogen and LH during the perioestrous period in prepubertal gilts induced to ovulate and mature gilts. | The temporal relationships of serum prolactin, oestrogen and LH concentrations during the perioestrous period were compared in prepubertal gilts induced to ovulate by PMSG and hCG and in mature gilts. In Exp. 1, 2 sustained prolactin surges, beginning 4 days and 1 day before the preovulatory LH surge, occurred in all m... | ['Animals', 'Chorionic Gonadotropin', 'Estrogens', 'Estrus', 'Female', 'Gonadotropins, Equine', 'Luteinizing Hormone', 'Ovulation Induction', 'Prolactin', 'Sexual Maturation', 'Swine'] | 3,397,954 | [['B01.050'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D27.505.696.399.472.277'], ['G08.686.195.500'], ['D06.472.699.322.451', 'D06.472.699.649.451', 'D12.644.548.726.451', 'D12.776.780.451'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Loss of BRCA1 leads to an increased sensitivity to Bisphenol A. | Humans are chronically exposed to the plasticizer, Bisphenol A (BPA), that can adversely affect the normal hormonal regulation of cellular functions by mimicking the actions of estrogen. This biological response to BPA may vary according to an individual's genetic characteristics (e.g., BRCA1 mutations or deletion). In... | ['Animals', 'BRCA1 Protein', 'Benzhydryl Compounds', 'Cell Line, Tumor', 'Cell Proliferation', 'Estradiol', 'Estrogen Receptor alpha', 'Female', 'Fulvestrant', 'Humans', 'Mammary Glands, Animal', 'Mice', 'Mice, Inbred C57BL', 'Phenols', 'Tamoxifen'] | 20,868,731 | [['B01.050'], ['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['D02.455.426.559.389.115'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D12.776.826.750.350.174'], ['D04.210.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
From recreation to creative expression: the essential features of an adolescent inpatient psychosocial support programme. | INTRODUCTION: Adolescent Inpatient Units are now an established component of leading tertiary children's hospitals in the developed world. While different methods have been used to provide psychosocial support in these settings, there is little recent literature about these programmes. We aimed to identify programme go... | ['Adolescent', 'Chronic Disease', 'Communication', 'Hospital Units', 'Humans', 'Recreation', 'Social Identification', 'Social Support', 'Victoria'] | 12,625,100 | [['M01.060.057'], ['C23.550.291.500'], ['F01.145.209', 'L01.143'], ['N02.278.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.450.642'], ['F01.145.813.708'], ['I01.880.853.500.600'], ['Z01.639.100.992', 'Z01.678.100.373.992']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
4,4'-Dinitrodiphenyldisulfides of different charge type as probes for the electrostatic environment of sulfhydryl groups. | 5,5'-Dithiobis-(2-nitro-N-trimethylbenzyl ammonium iodide) (I) and 5,5'-dithiobis-(2-nitro-N-2'-hydroxyethyl benzamide) (II) were synthesized as positively charged and neutral analogs of Ellman's reagent (5,5'-dithiobis-(2-nitrobenzoic acid) (III). Their reaction rates with a variety of thiols with different charge sho... | ['Binding Sites', 'Calorimetry', 'Disulfides', 'Dithionitrobenzoic Acid', 'Dithiothreitol', 'Kinetics', 'Methods', 'Nitrobenzenes', 'Sulfhydryl Compounds', 'Temperature', 'Thermodynamics', 'Thiocholine', 'Thioglycolates'] | 1,174,562 | [['G02.111.570.120'], ['E05.196.131'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D02.241.223.100.600.300', 'D02.455.426.559.389.127.650.300'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['G01.374.661', 'G02.111.490'], ['E05.581'], ['D02.455.426.559.389.565', 'D02.640.529'], ['... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Regional nerve blocks. Part 8--Using a nerve stimulator to locate peripheral nerves. | This is a relatively specialised technique aimed more at enhancing the skills of doctors regularly performing local anaesthetic blocks. It is a useful device for confirming the location of major nerves and plexuses proximally, but not necessary for most peripheral nerve blocks. | ['Electric Stimulation', 'Humans', 'Nerve Block', 'Peripheral Nervous System'] | 11,838,395 | [['E05.723.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E03.155.086.711', 'E04.525.210.550'], ['A08.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Shall we upgrade one-dimensional secondary settler models used in WWTP simulators? - An assessment of model structure uncertainty and its propagation. | In WWTP models, the accurate assessment of solids inventory in bioreactors equipped with solid-liquid separators, mostly described using one-dimensional (1-D) secondary settling tank (SST) models, is the most fundamental requirement of any calibration procedure. Scientific knowledge on characterising particulate organi... | ['Bioreactors', 'Computer Simulation', 'Models, Theoretical', 'Uncertainty', 'Waste Disposal, Fluid'] | 21,866,774 | [['E07.115', 'J01.897.120.115'], ['L01.224.160'], ['E05.599'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.715.360.750.625.850', 'N06.850.520.830.600.900'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Cloning, sequencing, and expression of ruvB and characterization of RuvB proteins from two distantly related thermophilic eubacteria. | The ruvB genes of the highly divergent thermophilic eubacteria Thermus thermophilus and Thermotoga maritima were cloned, sequenced, and expressed in Escherichia coli. Both thermostable RuvB proteins were purified to homogeneity. Like E. coli RuvB protein, both purified thermostable RuvB proteins showed strong double-st... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Bacterial Proteins', 'Base Sequence', 'Binding, Competitive', 'Cloning, Molecular', 'DNA Helicases', 'DNA, Bacterial', 'DNA, Superhelical', 'Escherichia coli', 'Gene Expression', 'Genes, Bacterial', 'Genetic Complementation Test', 'Gram-Negative Anaerobic Bacteri... | 8,626,340 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['E05.393.220'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D13.444.308.212']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes: ACCP evidenced-based clinical practice guidelines (2nd edition). | BACKGROUND: This chapter of the guidelines is intended to provide an evidence-based assessment of the initial evaluation of patients recognized as having lung cancer and the recognition of paraneoplastic syndromes.METHODS: The current medical literature that is applicable to this issue was identified by a computerized ... | ['Diagnostic Techniques, Respiratory System', 'Evidence-Based Medicine', 'Humans', 'Lung Neoplasms', 'Neoplasm Metastasis', 'Paraneoplastic Syndromes'] | 17,873,166 | [['E01.370.386'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650', 'C23.550.727.650'], ['C04.730']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of non-sinusoidal pitching motion on the propulsion performance of an oscillating foil. | Numerical simulations have been used in this paper to study the propulsion device of a wave glider based on an oscillating hydrofoil, in which the profile of the pitching and heaving motion have been prescribed for the sake of simplicity. A grid model for a two-dimensional NACA0012 hydrofoil was built by using the dyna... | ['Humans', 'Hydrodynamics', 'Models, Statistical', 'Oceans and Seas', 'Renewable Energy', 'Rheology', 'Ships', 'Software'] | 31,260,479 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.342'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['N06.230.132.644'], ['E05.830', 'H01.671.808'], ['J01.937.817'], ['L01.224.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Sagittal alignment of the cervical spine in adolescent idiopathic scoliosis treated by posteromedial translation. | PURPOSE: To analyze postoperative changes in the cervical sagittal alignment (CSA) of patients with AIS treated by posteromedial translation.METHODS: 49 patients with thoracic AIS underwent posterior arthrodesis with hybrid constructs, combining lumbar pedicle screws and thoracic universal clamps. Posteromedial transla... | ['Adolescent', 'Bone Screws', 'Cervical Vertebrae', 'Female', 'Humans', 'Kyphosis', 'Lordosis', 'Male', 'Postoperative Period', 'Radiography', 'Scoliosis', 'Spinal Fusion', 'Thoracic Vertebrae', 'Treatment Outcome'] | 22,965,380 | [['M01.060.057'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.800.500'], ['C05.116.900.800.750'], ['E04.614.750', 'N02.421.585.753.750'], ['E01.370.350.700'], ['C05.116.900.800.875'], ['E04.555.100.700... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Complications of mandible fractures related to substance abuse. | PURPOSE: To analyze different epidemiologic factors related to patients who abuse legal and illegal substances, and the relationship between substance abuse and postsurgical complications of mandibular fractures.PATIENTS AND METHODS: The study was performed over a 5-year period by the Division of Oral and Maxillofacial... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Fracture Healing', 'Fractures, Malunited', 'Humans', 'Male', 'Mandibular Fractures', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Smoking', 'Substance-Related Disorders', 'Surgical Wound Infection', 'Violence'] | 18,848,098 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['G16.762.891.500'], ['C26.404.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.900.300.284.500.400.255', 'C26.404.750.467.441', 'C26.915.300.425.500.400.255'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Negotiating home base: Narratives of psychological well-being among female military members. | The current study aimed to understand how active duty service women with low levels of current psychological distress make sense of their military experiences in ways that might contribute to psychological well-being. Semi-structured interviews were conducted with active duty female members in the Canadian Forces and t... | ['Adult', 'Canada', 'Female', 'Humans', 'Mental Health', 'Military Personnel', 'Narration', 'Negotiating', 'Stress, Psychological', 'Young Adult'] | 29,414,421 | [['M01.060.116'], ['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['M01.526.625'], ['E05.318.308.502', 'F01.145.209.459', 'L01.399.250.660', 'N05.715.360.300.480', 'N06.850.520.308.502'], ['F01.145.209.520', 'F01.829.401.520', 'F02.463.785.373.520', 'L01.143.620', 'N04.... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A tumor immunotherapy technique based on modulation of the idiotype anti-idiotype network. | In this communication I propose a technique for manipulating the idiotype anti-idiotype network with the aim of enhancing the immune response to tumors. The theoretical basis for this technique follows from Jerne's network theory of the immune system. By tolerizing the host to immunoglobulin bearing idiotypes directed ... | ['B-Lymphocytes', 'Humans', 'Immunoglobulin Idiotypes', 'Immunotherapy', 'Lymphocyte Activation', 'Models, Biological', 'Neoplasms', 'T-Lymphocytes'] | 3,878,450 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.745', 'D12.776.124.486.485.680.745', 'D12.776.124.790.651.680.745', 'D12.776.377.715.548.680.745', 'D23.050.550.750', 'G02.111.570.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of exercise-induced elevation in core temperature on cold-induced vasodilatation response in toes. | Cold-induced vasodilatation (CIVD) has been proposed as a potential protective mechanism against cold injuries during exposure of extremities to a cold environment. The purpose of this study was to evaluate the effect of exercise and the associated elevation in core temperature on toe skin temperatures during immersion... | ['Adaptation, Physiological', 'Adult', 'Body Temperature', 'Body Temperature Regulation', 'Cold Temperature', 'Exercise', 'Humans', 'Male', 'Thermosensing', 'Toes', 'Vasoconstriction', 'Vasodilation'] | 19,319,561 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['E01.370.600.875.374', 'G07.110'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The life and death of Ismar Boas. | Dr. Ismar Boas (1858-1938) was the founder of the medical subspecialty of gastroenterology. In 1886, he opened in Berlin the first specialty clinic for the study of digestive diseases. In 1895, he founded the first journal devoted to gastroenterology. During his long and productive career, Boas was a pioneer in nearly ... | ['Gastroenterology', 'Germany', 'History, 19th Century', 'History, 20th Century', 'Occult Blood'] | 3,282,002 | [['H02.403.429.405'], ['Z01.542.315'], ['K01.400.504.937'], ['K01.400.504.968'], ['E01.370.225.925', 'E05.200.925']] | ['Disciplines and Occupations [H]', 'Geographicals [Z]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Laser photocoagulation combined with subtenon injection of triamcinolone acetonide for diabetic cystoid macular edema. | BACKGROUND: To compare the effects of laser photocoagulation combined with subtenon injection of triamcinolone acetonide with photocoagulation alone, for diabetic cystoid macular edema.METHODS: This retrospective comparative study analyzed data for 34 eyes with cystoid macular edema treated with photocoagulation alone ... | ['Adult', 'Aged', 'Combined Modality Therapy', 'Diabetic Retinopathy', 'Female', 'Humans', 'Injections', 'Laser Coagulation', 'Macular Edema', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome', 'Triamcinolone Acetonide'] | 19,403,007 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['E02.520.745.410', 'E02.594.530', 'E04.014.520.530', 'E04.350.750.410', 'E04.540.630.410'], ['C11.768.585.439.245'], ['M01.060.116.630'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A new and general method for blind shift-variant deconvolution of biomedical images. | We present a new method for blind deconvolution of multiple noisy images blurred by a shift-variant point-spread-function (PSF). We focus on a setting in which several images of the same object are available, and a transformation between these images is known. This setting occurs frequently in biomedical imaging, for e... | ['Algorithms', 'Animals', 'Artificial Intelligence', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Pattern Recognition, Automated', 'Rats', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 18,051,125 | [['G17.035', 'L01.224.050'], ['B01.050'], ['G17.035.250', 'L01.224.050.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['L01.399.750'], ['B01.050.150.900.649.313... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Laser surgery in dark skin. | Although challenging, effective laser surgery in patients with darker skin tones can be achieved despite a higher inherent risk of untoward side effects. While the incidence of undesirable postoperative sequelae has decreased with the development of advanced laser technology and individualized treatment parameters, the... | ['Humans', 'Laser Therapy', 'Skin Diseases', 'Skin Pigmentation', 'Treatment Outcome'] | 14,673,304 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['C17.800'], ['E01.370.600.115.450.500', 'E01.370.600.620.750', 'G07.100.175.500', 'G13.750.837', 'G16.690.890'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Assembly of the aspartate transcarbamoylase holoenzyme from transcriptionally independent catalytic and regulatory cistrons. | The cistrons encoding the regulatory and catalytic polypeptides of aspartate transcarbamoylase (EC 2.1.3.2) from Escherichia coli K-12 have been cloned separately on plasmids from different incompatability groups. The catalytic cistron (pyrB) was carried by pACYC184 and expressed from its own promoter, whereas the regu... | ['Aspartate Carbamoyltransferase', 'Chloromercuribenzoates', 'Escherichia coli', 'Genes', 'Genes, Bacterial', 'Macromolecular Substances', 'Molecular Weight', 'Plasmids', 'Transcription, Genetic', 'p-Chloromercuribenzoic Acid'] | 6,365,893 | [['D08.811.641.500', 'D08.811.913.555.275.200'], ['D02.241.223.100.200.311', 'D02.241.223.100.500.261', 'D02.455.426.559.389.127.250.311', 'D02.455.426.559.389.127.500.261', 'D02.691.750.740.644.261'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.249', 'G05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tendon material properties vary and are interdependent among turkey hindlimb muscles. | The material properties of a tendon affect its ability to store and return elastic energy, resist damage, provide mechanical feedback and amplify or attenuate muscle power. While the structural properties of a tendon are known to respond to a variety of stimuli, the extent to which material properties vary among indivi... | ['Animals', 'Elastic Modulus', 'Elasticity', 'Hindlimb', 'Muscle Contraction', 'Muscle Strength', 'Muscle, Skeletal', 'Stress, Mechanical', 'Tendons', 'Tensile Strength', 'Turkeys'] | 22,771,746 | [['B01.050'], ['G01.374.590.605'], ['G01.374.590'], ['A13.473'], ['G11.427.494'], ['E01.370.600.425', 'G11.427.560'], ['A02.633.567', 'A10.690.552.500'], ['G01.374.835'], ['A02.880'], ['G01.374.850'], ['B01.050.150.900.248.350.800', 'B01.050.150.900.248.690.800']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study of Staphylococcus aureus collected at slaughter from dairy cows with chronic mastitis. | Staphylococcus aureus is one of the most important pathogens associated with bovine mastitis. Recent studies have shown that Staph. aureus strains may differ in virulence, and in their ability to disseminate across commercial dairy herds. The goal of this study was to determine whether Staph. aureus isolates differed i... | ['Animals', 'Bacterial Toxins', 'Cattle', 'DNA, Bacterial', 'Electrophoresis, Gel, Pulsed-Field', 'Enterotoxins', 'Female', 'Hemolysin Proteins', 'Mammary Glands, Animal', 'Mastitis, Bovine', 'Milk', 'Polymerase Chain Reaction', 'Sphingomyelin Phosphodiesterase', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 22,369,758 | [['B01.050'], ['D23.946.123'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.212'], ['E05.196.401.220', 'E05.301.300.220'], ['D23.946.330'], ['D12.776.543.695.444'], ['A10.336.482', 'A13.589'], ['C22.196.581'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Prevalence of carotid atherosclerosis in hypertension: preliminary baseline data from the European Lacidipine Study on Atheroscelerosis (ELSA). | In the ELSA trial, the effects of lacidipine-based treatment and beta-blocker (atenolol)-based treatment on the development and progression of carotid wall alterations are assessed in hypertensive patients. The primary endpoint of this study is the rate of change in the intima-media thickness of the carotid artery wall... | ['Antihypertensive Agents', 'Arteriosclerosis', 'Carotid Artery Diseases', 'Dihydropyridines', 'Europe', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Prevalence'] | 8,973,780 | [['D27.505.954.411.162'], ['C14.907.137.126'], ['C10.228.140.300.200', 'C14.907.253.123'], ['D03.383.725.203'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.7... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Retinitis pigmentosa and discoid lupus erythematosus. | A 41 year old male is presented who suffers from both advanced retinitis pigmentosa and active discoid lupus erthematosus. A possible association between the two pigmenting disorders is discussed as well as the treatment of the discoid lupus with potentially retinotoxic hydroxychloroquine. | ['Adult', 'Electroretinography', 'Fundus Oculi', 'Humans', 'Hydroxychloroquine', 'Lupus Erythematosus, Discoid', 'Male', 'Retinitis Pigmentosa'] | 1,484,501 | [['M01.060.116'], ['E01.370.380.225', 'E01.370.405.270'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.810.050.180.350'], ['C17.300.475.479', 'C17.800.480.479'], ['C11.270.684', 'C11.768.585.658.500', 'C16.320.290.684']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stem cell factor in mast cells and increased mast cell density in idiopathic and ischemic cardiomyopathy. | BACKGROUND: We compared cardiac mast cell (HHMC) density and the immunological and nonimmunological release of mediators from mast cells isolated from heart tissue of patients with idiopathic dilated (DCM) (n=24) and ischemic cardiomyopathy (ICM) (n = 10) undergoing heart transplantation and from control subjects (n = ... | ['Adult', 'Cardiomyopathy, Hypertrophic', 'Cell Count', 'Female', 'Humans', 'Male', 'Mast Cells', 'Middle Aged', 'Myocardial Reperfusion Injury', 'Stem Cell Factor'] | 9,529,265 | [['M01.060.116'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.427', 'A15.382.652'], ['M01.060.116.630'], ['C14.280.238.615', 'C14.280.647.625', 'C14.907.585.625', 'C14.907.725.600', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
On the mechanics underlying the reservoir-excess separation in systemic arteries and their implications for pulse wave analysis. | Several works have separated the pressure waveform p in systemic arteries into reservoir p(r) and excess p(exc) components, p = p(r) + p(exc), to improve pulse wave analysis, using windkessel models to calculate the reservoir pressure. However, the mechanics underlying this separation and the physical meaning of p(r) a... | ['Arteries', 'Blood Flow Velocity', 'Blood Pressure', 'Humans', 'Models, Cardiovascular', 'Pulsatile Flow'] | 21,165,776 | [['A07.015.114'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161'], ['G01.482.620', 'G09.330.380.630.555']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro culture and harvest of BMMSCs on the surface of a novel thermosensitive glass microcarrier. | Traditional two-dimensional (2D) static culture environment for stem cells followed by enzymatic cell detachment or mechanical treatment is routinely used in research laboratories. However, this method is not ideal as stem cells expand slowly, with cell damage and partial loss of specific stemness. For this reason, a b... | ['Animals', 'Bone Marrow Cells', 'Cell Adhesion', 'Cell Culture Techniques', 'Cell Survival', 'Cells, Cultured', 'Glass', 'Mesenchymal Stem Cells', 'Polymers', 'Rats', 'Surface Properties', 'Temperature'] | 26,478,317 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.022'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.346'], ['A11.251'], ['J01.637.437'], ['A11.329.830.500', 'A11.872.590.500'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['B01.050.150.900.649.313.992.635.505.700'], ['G02.860'], ['G... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Genome-wide analysis of immune activation in human T and B cells reveals distinct classes of alternatively spliced genes. | Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion/exclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyte activation, little is known about the role it plays during the immun... | ['Alternative Splicing', 'Antigens, CD19', 'B-Lymphocytes', 'CD2 Antigens', 'Exons', 'Gene Expression Profiling', 'Genome-Wide Association Study', 'Humans', 'Immune System', 'Lymphocyte Activation', 'Models, Biological', 'Oligonucleotide Array Sequence Analysis', 'RNA, Messenger', 'Signal Transduction', 'T-Lymphocytes'... | 19,936,255 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['D23.050.301.264.035.119', 'D23.050.301.264.051.119', 'D23.050.301.500.600.200', 'D23.050.705.552.600.200', 'D23.101.100.110.119', 'D23.101.100.150.119'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A1... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Measuring Blood Pressure Using a Noninvasive Tail Cuff Method in Mice. | The renin angiotensin system (RAS) is well known for its role in regulating blood pressure (BP). An activated RAS contributes to elevated blood pressure and is evident in both human and animal models of hypertension. Drugs that target the classic vasoconstrictive arm of the RAS (angiotensin II/AT1 receptor signaling) a... | ['Angiotensin I', 'Animals', 'Blood Pressure', 'Blood Pressure Determination', 'Hypertension', 'Mice', 'Peptide Fragments', 'Renin-Angiotensin System', 'Software', 'Tail'] | 28,500,596 | [['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['C14.907.489'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.541'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Action potential clamp and mefloquine sensitivity of recombinant 'I KS' channels incorporating the V307L KCNQ1 mutation. | The slow delayed rectifier potassium current, 'I(Ks)', contributes to repolarisation of cardiac ventricular action potentials and thereby to the duration of the QT interval of the electrocardiogram. Mutations to I(Ks) channel subunits occur in clinically significant cardiac repolarisation disorders. The short QT syndro... | ['Action Potentials', 'Animals', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Electrocardiography', 'Electrophysiology', 'Inhibitory Concentration 50', 'KCNQ1 Potassium Channel', 'Mefloquine', 'Mutation', 'Patch-Clamp Techniques', 'Potassium Channel Blockers', 'Potassium Channels, Voltage-Gated'] | 20,436,212 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['H01.158.344.528', 'H01.158.782.236'], ['E05.940.350', 'G07.690.936.563'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of deletion of glycerol-3-phosphate dehydrogenase and glutamate dehydrogenase genes on glycerol and ethanol metabolism in recombinant Saccharomyces cerevisiae. | Bioethanol is currently used as an alternative fuel for gasoline worldwide. For economic production of bioethanol by Saccharomyces cerevisiae, formation of a main by-product, glycerol, should be prevented or minimized in order to reduce a separation cost of ethanol from fermentation broth. In this study, S. cerevisiae ... | ['Ethanol', 'Gene Deletion', 'Genetic Enhancement', 'Glutamate Dehydrogenase', 'Glycerol', 'Glycerolphosphate Dehydrogenase', 'Recombination, Genetic', 'Saccharomyces cerevisiae'] | 21,909,679 | [['D02.033.375'], ['G05.365.590.762.320', 'G05.558.800.320'], ['E05.104.500', 'E05.393.420.451', 'J01.897.120.050.250.500'], ['D08.811.682.664.500.398'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D08.811.682.047.150.700.400'], ['G05.728'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Short-term stress-relaxation behavior of nonmetallic restoratives. | The rheological behavior of five nonmetallic dental materials was studied. Short-term stress relaxation was found to be strongly dependent on time and temperature. Relaxation behavior of the test materials conformed well to simple mathematical models. | ['Dental Cements', 'Dental Restoration, Permanent', 'Elasticity', 'Polycarboxylate Cement', 'Resins, Synthetic', 'Silicate Cement', 'Stress, Mechanical', 'Temperature', 'Time Factors', 'Zinc Phosphate Cement'] | 1,059,653 | [['D25.339.291', 'J01.637.051.339.291'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['G01.374.590'], ['D25.339.291.700', 'J01.637.051.339.291.700'], ['D05.750.716.822', 'D25.339.816', 'D25.720.716.822', 'J01.637.051.339.816', 'J01.637.051.720.716.822'], ['D25.339.291.800', 'J01.637.051.339.291.800'], ['G01.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The effect of naloxone on audiogenic seizures. | The severity of audiogenic seizures was increased in two strains of mice 5--10 min after naloxone (2 or 4 mg/kg IP). This may indicate involvement of an endorphin or enkephalin in the modulation of reactivity. | ['Acoustic Stimulation', 'Animals', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Naloxone', 'Seizures', 'Species Specificity', 'Stimulation, Chemical'] | 119,265 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management of late cases of esophageal disruption with intravenous hyperalimentation. | Among fourteen patients with disruption of the thoracic esophagus, the overall mortality rate was 36%. The mortality was greatly reduced in a group of five of these patients who were treated by closed-chest tube drainage and intravenous hyperalimentation. The cause of death in most cases was sepsis and malnutrition. Al... | ['Adult', 'Age Factors', 'Aged', 'Drainage', 'Esophageal Diseases', 'Esophageal Perforation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Ontario', 'Parenteral Nutrition', 'Rupture, Spontaneous'] | 804,343 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E02.309', 'E04.237'], ['C06.405.117'], ['C06.405.117.468', 'C26.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567.176.639'], ['E02.421.505', 'E02.642.500.505'], ['C23.300.909']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A rat model for determining the postprandial response to foods. | BACKGROUND: The use of small animal models for studying postprandial changes in circulating nutrients, hormones and metabolic biomarkers is hampered by the limited quantity of blood that can be withdrawn for analysis. Here, we describe the development of an unrestrained, meal-fed rat model, having a permanent or tempor... | ['Animals', 'Blood Glucose', 'Catheters, Indwelling', 'Circadian Rhythm', 'Dietary Carbohydrates', 'Insulin', 'Male', 'Models, Animal', 'Postprandial Period', 'Rats, Sprague-Dawley', 'Veins'] | 27,404,497 | [['B01.050'], ['D09.947.875.359.448.500'], ['E07.132.500'], ['G07.180.562.190'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['E05.598'], ['G10.261.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A07.015.908']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Experimental determination of the dose kernel in high-energy x-ray beams. | A semiempirical method to characterize the pencil-beam dose kernel is presented. Results from measurements are described by mathematical models of the applicable physical processes. The measurements were made with 6 and 25 MV x-ray beams from a linear accelerator. Broad-beam notations were used consistently, and the pe... | ['Algorithms', 'Biophysical Phenomena', 'Biophysics', 'Electrons', 'Humans', 'Mathematics', 'Models, Biological', 'Monte Carlo Method', 'Neoplasms', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, High-Energy', 'Scattering, Radiation'] | 9,157,261 | [['G17.035', 'L01.224.050'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['G01.249.335', 'G01.358.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['E05.599.395'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['C04'], ['E02.950.825', 'L01.313.500.750.100... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Alternatives to retroorbital blood collection in hispid cotton rats (Sigmodon hispidus). | Cotton rats (Sigmodon hispidus) are a valuable animal model for many human viral diseases, including polio virus, measles virus, respiratory syncytial virus, and herpes simplex virus. Although cotton rats have been used in research since 1939, few publications address handling and sampling techniques for this species, ... | ['Anesthesia', 'Animals', 'Animals, Laboratory', 'Behavior, Animal', 'Blood Specimen Collection', 'Female', 'Sigmodontinae'] | 22,776,125 | [['E03.155'], ['B01.050'], ['B01.050.050.199'], ['F01.145.113'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['B01.050.150.900.649.313.992.635.075.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relations among musical skills, phonological processing, and early reading ability in preschool children. | We examined the relations among phonological awareness, music perception skills, and early reading skills in a population of 100 4- and 5-year-old children. Music skills were found to correlate significantly with both phonological awareness and reading development. Regression analyses indicated that music perception sk... | ['Auditory Perception', 'Awareness', 'Child Development', 'Child, Preschool', 'Female', 'Humans', 'Language Development', 'Male', 'Music', 'Phonetics', 'Reading', 'Task Performance and Analysis'] | 12,408,958 | [['F02.463.593.071', 'G07.888.125'], ['F02.463.188.150'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.525.200.310'], ['K01.602'], ['L01.559.598.518'], ['L01.559.423.557'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Humanities [K]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Klotho Deficiency Induces Arteriolar Hyalinosis in a Trade-Off with Vascular Calcification. | Hyalinosis is a vascular lesion affecting the renal vasculature and contributing to aging-related renal function decline. We assessed whether arteriolar hyalinosis is caused by Klotho deficiency, a state known to induce both renal and vascular phenotypes associated with aging. Histochemistry was used to assess hyalinos... | ['Animals', 'Arteriolosclerosis', 'Cells, Cultured', 'Glucuronidase', 'Kidney', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Muscle, Smooth, Vascular', 'Vascular Calcification'] | 31,539,519 | [['B01.050'], ['C14.907.137.126.056'], ['A11.251'], ['D08.811.277.450.426'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.6... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tailored liquid chromatography-mass spectrometry analysis improves the coverage of the intracellular metabolome of HepaRG cells. | Metabolomics protocols are often combined with Liquid Chromatography-Mass Spectrometry (LC-MS) using mostly reversed phase chromatography coupled to accurate mass spectrometry, e.g. quadrupole time-of-flight (QTOF) mass spectrometers to measure as many metabolites as possible. In this study, we optimised the LC-MS sepa... | ['Cell Line, Tumor', 'Chromatography, Liquid', 'Chromatography, Reverse-Phase', 'Humans', 'Mass Spectrometry', 'Metabolome', 'Metabolomics'] | 28,153,450 | [['A11.251.210.190', 'A11.251.860.180'], ['E05.196.181.400'], ['E05.196.181.400.495'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['G03.500'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuronal calcium sensor-1 deletion in the mouse decreases motivation and dopamine release in the nucleus accumbens. | Calcium sensors detect intracellular calcium changes and interact with downstream targets to regulate many functions. Neuronal Calcium Sensor-1 (NCS-1) or Frequenin is widely expressed in the nervous system, and involved in neurotransmission, synaptic plasticity and learning. NCS-1 interacts with and regulates dopamine... | ['Amphetamine', 'Animals', 'Central Nervous System Stimulants', 'Conditioning, Classical', 'Dopamine', 'Feeding Behavior', 'Food Preferences', 'Locomotion', 'Male', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Motivation', 'Motor Activity', 'Neuronal Calcium-Sensor Proteins', 'Neuropeptides', 'Nucleus Accumbens', 'Satiety ... | 26,738,968 | [['D02.092.471.683.152.110'], ['B01.050'], ['D27.505.696.282', 'D27.505.954.427.220'], ['F02.463.425.179.308'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.407.516', 'G07.203.650.353.516'], ['G07.568.500', 'G11.427.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensitive detection of fluorescence in western blotting by merging images. | The western blotting technique is widely used to analyze protein expression levels and protein molecular weight. The chemiluminescence method is mainly used for detection due to its high sensitivity and ease of manipulation, but it is unsuitable for detailed analyses because it cannot be used to detect multiple protein... | ['Animals', 'Blotting, Western', 'Cell Line', 'Fluorescent Dyes', 'Glutathione Transferase', 'Image Enhancement', 'Luminescent Measurements', 'Mice', 'Microscopy, Fluorescence', 'Recombinant Proteins', 'Sensitivity and Specificity'] | 29,352,284 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D08.811.913.225.500'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E05.196.712.516'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Efficacy and safety of Maekmoondong-tang for chronic dry cough: a study protocol for a randomized controlled trial. | BACKGROUND: Chronic cough, defined it lasts more than 8 weeks. The symptom is common, but highly troublesome, and it reduces quality of life. Despite much effort to develop a protocol for diagnosis and treatment of chronic cough, it remains problematic to determine its cause. As a result, treatment is often unsuccessfu... | ['Adult', 'Aged', 'Chronic Disease', 'Clinical Protocols', 'Cough', 'Double-Blind Method', 'Drugs, Chinese Herbal', 'Humans', 'Medicine, Korean Traditional', 'Middle Aged', 'Phytotherapy', 'Plants, Medicinal', 'Young Adult'] | 26,829,923 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.500'], ['E02.183', 'N05.715.360.330.125'], ['C08.618.248', 'C23.888.852.293'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Use of calorie information at fast food and chain restaurants among US youth aged 9-18 years, 2010. | BACKGROUND: To examine whether youth use calorie information when it is available at fast food/chain restaurants and what factors are associated with using this information to make their food selection.METHODS: A cross-sectional analysis was conducted on a sample of 721 youth (9-18 years) using the 2010 YouthStyles and... | ['Adolescent', 'Cross-Sectional Studies', 'Energy Intake', 'Fast Foods', 'Female', 'Food', 'Food Labeling', 'Health Surveys', 'Humans', 'Male', 'Obesity', 'Restaurants', 'Sex Factors', 'United States'] | 23,697,388 | [['M01.060.057'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240.340'], ['G07.203.300.477', 'J02.500.477'], ['G07.203.300', 'J02.500'], ['J01.576.423.850.600.400', 'J01.576.761.400.450'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Study on a real-time BEAM system for diagnosis assistance based on a system on chips design. | As an innovative as well as an interdisciplinary research project, this study performed an analysis of brain signals so as to establish BrainIC as an auxiliary tool for physician diagnosis. Cognition behavior sciences, embedded technology, system on chips (SOC) design and physiological signal processing are integrated ... | ['Algorithms', 'Brain Mapping', 'Brain Waves', 'Computer Systems', 'Electrodes', 'Electroencephalography', 'Equipment Design', 'Fuzzy Logic', 'Humans', 'Signal Processing, Computer-Assisted', 'Sleep Stages'] | 23,681,095 | [['G17.035', 'L01.224.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300.150', 'E01.370.405.245.287', 'G07.265.087', 'G11.561.127'], ['L01.224.230'], ['E07.305.250'], ['E01.370.376.300', 'E01.370.405.245'], ['E05.320'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Quenching of red cell tryptophan fluorescence by mercurial compounds. | Intrinsic tryptophan fluorescence in red cell ghost membranes labeled with N-ethylmaleimide (N-EM) is quenched in a dose-dependent manner by the organic mercurial p-chloromercuribenzene sulfonate (p-CMBS). Fluorescence lifetime analysis shows that quenching occurs by a static mechanism. Binding of p-CMBS occurs by a ra... | ['Anion Exchange Protein 1, Erythrocyte', 'Biological Transport', 'Body Water', 'Chloromercuribenzoates', 'Depression, Chemical', 'Dose-Response Relationship, Drug', 'Erythrocyte Membrane', 'Ethylmaleimide', 'Fluorescence', 'Humans', 'Kinetics', 'Phenylmercuric Acetate', 'Protein Binding', 'Tryptophan', 'Urea', 'p-Chlo... | 3,574,139 | [['D12.776.157.530.450.162.193.500', 'D12.776.157.530.450.437.249.500', 'D12.776.157.530.937.656.249.500', 'D12.776.543.550.190.276.500', 'D12.776.543.550.779.249.500', 'D12.776.543.585.450.162.193.500', 'D12.776.543.585.450.437.249.500', 'D12.776.543.585.937.776.249.500'], ['G03.143'], ['A12.207.200'], ['D02.241.223.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visit preferences of middle-aged vs older critically ill patients. | OBJECTIVE: To differentiate between middle-aged and older adults' visiting preferences in critical care settings.DESIGN: Patients' preferences for visiting, perceptions of illness severity and extent of fatigue associated with visiting and an objective measurement of illness severity while in critical care were surveye... | ['Adult', 'Age Factors', 'Aged', 'Attitude to Health', 'Choice Behavior', 'Critical Care', 'Fatigue', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Nursing Assessment', 'Organizational Policy', 'Patient Care Planning', 'Surveys and Questionnaires', 'Time Factors', 'Visitors to Patients'] | 8,358,481 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['F02.463.785.373.346'], ['E02.760.190', 'N02.421.585.190'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01.060.116.630'], ['N04.590.233.508.480'], ['I01.655.500.5... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Colon carcinoma in pregnancy. Case report and review of literature. | The Authors report on a case of colon carcinoma occurred in a pregnant woman. As complaints for digestive tract disfunctions are common during pregnancy, the diagnosis of the malignancy was delayed. The Authors suggest the treating physician be alert to avoid under estimation of symptomatology. | ['Adenocarcinoma', 'Adult', 'Colonic Neoplasms', 'Female', 'Humans', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Time Factors'] | 6,713,660 | [['C04.557.470.200.025'], ['M01.060.116'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C04.850', 'C13.703.720'], ['G01.910.857']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Novel gluten-free formulations from lentil flours and nutritional yeast: Evaluation of extrusion effect on phytochemicals and non-nutritional factors. | The food industry is increasingly innovating and applying new processing technologies and ingredients to develop novel food products that meet the consumers' demand. In this study, the effect of extrusion (at 140 °C and 160 °C) was evaluated in different lentil flours formulations enriched with nutritional yeast, in te... | ['Animals', 'Chromatography, High Pressure Liquid', 'Diet, Gluten-Free', 'Flour', 'Food Analysis', 'Food, Formulated', 'Food-Processing Industry', 'Galactosides', 'Hemagglutination Tests', 'Inositol Phosphates', 'Lens Plant', 'Oligosaccharides', 'Phytochemicals', 'Rats', 'Trypsin Inhibitors', 'Yeast, Dried'] | 31,991,254 | [['B01.050'], ['E05.196.181.400.300'], ['E02.642.249.265', 'G07.203.650.240.265'], ['G07.203.300.484', 'J02.500.484'], ['E05.362', 'J01.576.423.850.100'], ['G07.203.300.525.350', 'J02.500.525.350'], ['J01.576.423.200.400'], ['D09.408.320'], ['E01.370.225.812.735.050.375', 'E05.200.812.735.050.375', 'E05.478.594.760.050... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Major vascular injury in laparoscopic urology. | BACKGROUND AND OBJECTIVES: Major vascular injury is the most devastating complication of laparoscopy, occurring most commonly during the laparoscopic entry phase. Our goal is to report our experience with major vascular injury during laparoscopic entry with closed- and open-access techniques in urologic procedures.METH... | ['Adult', 'Female', 'Humans', 'Incidence', 'Laparoscopy', 'Male', 'Postoperative Complications', 'United States', 'Urologic Diseases', 'Urologic Surgical Procedures', 'Vascular System Injuries'] | 25,392,667 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C23.550.767'], ['Z01.107.567.875'], ['C12.777', 'C13.351.968'], ['E04.950.774'], ['C14.907.93... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Relevance of a borderline vitamin deficiency in relation to the question of vitamin requirement. | A definition is given for the terms of latent and borderline vitamin deficiency, and the vitamin requirement and optimal vitamin supply, respectively, are discussed in relation to these two terms. The upper limit of the latent vitamin deficiency status can be used to define the optimal intake of vitamins, whereas the l... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Ascorbic Acid', 'Ascorbic Acid Deficiency', 'Avitaminosis', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nutritional Requirements', 'Sex Factors', 'Vitamins'] | 508,272 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lipoma of the larynx. | Two cases of intrinsic laryngeal lipoma are added to the twenty-four cases recorded previously. Lipoma may occur anywhere beneath the skin over the entire body. In the larynx these tumours lie rather deep and it is therefore important to obtain a deep tissue biopsy. It is possible to remove a substantial part of the sw... | ['Female', 'Humans', 'Laryngeal Neoplasms', 'Lipoma', 'Male', 'Middle Aged', 'Tomography, X-Ray'] | 3,430,055 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['C04.557.450.550.400'], ['M01.060.116.630'], ['E01.370.350.700.810', 'E01.370.350.825.810']] | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of two cysteine endopeptidases from latices of Morrenia brachystephana Griseb. and Morrenia odorata (Hook et Arn.) Lindley (Asclepiadaceae). | The properties of morrenain b II, a proteinase isolated from the latex of Morrenia brachystephana, were compared with those of morrenain o II, a proteinase obtained from the latex of Morrenia odorata. Both peptidases were purified to homogeneity by acetone precipitation followed by cation exchange chromatography. The e... | ['Amino Acid Sequence', 'Cysteine Endopeptidases', 'Hydrogen-Ion Concentration', 'Isoelectric Point', 'Kinetics', 'Latex', 'Molecular Sequence Data', 'Molecular Weight', 'Plant Proteins', 'Sequence Homology'] | 11,517,946 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['G02.300'], ['E05.301.300.663.500', 'G02.300.500'], ['G01.374.661', 'G02.111.490'], ['D05.750.078.625', 'D20.215.721.124', 'D25.720.099.625', 'D25.720.099.750.500', 'D25.720.327.840.239', 'J01.637.051.720.099.625', 'J0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Characterization of in vitro neural functional connectivity on a neurofluidic device. | Understanding the mechanism of functional connectivity in neural system is of great benefit to lot of researches and applications. Microfluidics and microelectrode arrays (MEAs) have been frequently utilized for in vitro neural cultures study. However, there are few studies on the functional connectivity of neural cult... | ['Animals', 'Cells, Cultured', 'Equipment Design', 'Hippocampus', 'Microelectrodes', 'Microfluidic Analytical Techniques', 'Nerve Net', 'Neurons', 'Neurophysiology', 'Rats', 'Rats, Sprague-Dawley', 'Tissue Array Analysis'] | 31,556,965 | [['B01.050'], ['A11.251'], ['E05.320'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E07.305.250.500'], ['E05.588.465'], ['A08.511'], ['A08.675', 'A11.671'], ['H01.158.610.268', 'H01.158.782.562'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.588.5... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence-based practice in neurology: a team approach to development. | Healthcare practitioners aspire to evidence-based practice, but in reality, many find it difficult to integrate the findings and recommendations of research studies and practice development projects into practice. One potential solution is a team approach to evaluating the available evidence and adapting it for use in ... | ['Benchmarking', 'Education, Nursing, Continuing', 'Evidence-Based Medicine', 'Humans', 'Inservice Training', 'Needs Assessment', 'Neurology', 'Nursing Staff, Hospital', 'Patient Care Team', 'Practice Guidelines as Topic', 'Program Development', 'Specialties, Nursing'] | 11,974,110 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['I02.358.212.450', 'I02.358.462.399'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['H02.403.600'], ['M01.526.485.680.49... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
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