Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Risk factors for arterial hypertension after liver transplantation. | Arterial hypertension represents a common complication of immunosuppressive therapy after liver transplantation (LT). The aim of the study is to evaluate the prevalence and risk factors associated with hypertension after LT. From a cohort of 323 cirrhotic patients who underwent LT from 2008 to 2012, 270 patients were r... | ['End Stage Liver Disease', 'Female', 'Graft Rejection', 'Humans', 'Hypertension', 'Immunosuppressive Agents', 'Liver Transplantation', 'Male', 'Middle Aged', 'Prevalence', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Severity of Illness Index', 'Tacrolimus', 'Treatment Outcome'] | 29,366,595 | [['C06.552.308.500.177'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D27.505.696.477.656'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', '... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
After Mexico Implemented a Tax, Purchases of Sugar-Sweetened Beverages Decreased and Water Increased: Difference by Place of Residence, Household Composition, and Income Level. | Background: In January 2014, Mexico implemented a tax on sugar-sweetened beverage (SSB) purchases of 1 peso/L.Objective: We examined the heterogeneity of changes in nonalcoholic beverage (SSB and bottled water) purchases after the tax was implemented by household income, urban and rural strata, and household compositio... | ['Adolescent', 'Adult', 'Beverages', 'Child', 'Commerce', 'Diet', 'Dietary Sucrose', 'Drinking', 'Family Characteristics', 'Food Preferences', 'Humans', 'Income', 'Mexico', 'Nutrition Policy', 'Residence Characteristics', 'Taxes', 'Urban Population', 'Water'] | 28,615,377 | [['M01.060.057'], ['M01.060.116'], ['G07.203.100', 'J02.200'], ['M01.060.406'], ['J01.219'], ['G07.203.650.240'], ['D09.301.831.250', 'D09.698.629.305.770.200', 'D09.947.500.250', 'D09.947.750.770.200', 'D27.720.372.300.353.609.750.250', 'G07.203.300.362.831.250', 'G07.203.300.514.500.400.700.750.250', 'J02.500.362.831... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Diet and health: scientific concepts and principles conference commentary. | The conference concluded that dietary guidelines are needed, but that they cannot apply to everyone in the population nor to the same extent. Furthermore, a mechanism or structure is needed in which the guidelines can be periodically reviewed and updated. In making dietary recommendations, genetic variability, age, sex... | ['Diet', 'Health', 'Humans', 'Nutritional Physiological Phenomena'] | 3,625,309 | [['G07.203.650.240'], ['N01.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Examination of the effect of increasing doses of etoricoxib on oral methotrexate pharmacokinetics in patients with rheumatoid arthritis. | The authors designed 2 randomized controlled studies to examine the effects of etoricoxib 60 to 120 mg daily on methotrexate pharmacokinetics in 50 rheumatoid arthritis (RA) patients on stable doses of methotrexate (7.5-20 mg). Patients received oral methotrexate at baseline and on days 7 and 14. In study 1, patients r... | ['Administration, Oral', 'Adult', 'Aged', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Cyclooxygenase 2 Inhibitors', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Drug Interactions', 'Drug Therapy, Combination', 'Etoricoxib', 'Female', 'Humans', 'Male', 'Methotrexate', 'Middle Aged', 'Pyridi... | 19,783,714 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['G07.690.773.875', 'G07.690.936.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Arginase-negative mutants of Arabidopsis exhibit increased nitric oxide signaling in root development. | Mutation of either arginase structural gene (ARGAH1 or ARGAH2 encoding arginine [Arg] amidohydrolase-1 and -2, respectively) resulted in increased formation of lateral and adventitious roots in Arabidopsis (Arabidopsis thaliana) seedlings and increased nitric oxide (NO) accumulation and efflux, detected by the fluoroge... | ['Amidohydrolases', 'Arabidopsis', 'Arabidopsis Proteins', 'Arginase', 'Arginine', 'Cells, Cultured', 'Glucuronidase', 'Indoleacetic Acids', 'Microscopy, Fluorescence', 'Mitochondria', 'Models, Molecular', 'Mutagenesis, Insertional', 'Mutation', 'Nitric Oxide', 'Plant Roots', 'Protein Isoforms', 'Recombinant Fusion Pro... | 18,567,826 | [['D08.811.277.087'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D08.811.277.913.292'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.251'], ['D08.811.277.450.426'], ['D03.066.288', 'D03.633.100.473.404'], ['E01.370.350.515.458', 'E05.595.458'], ['A11.284.430.214.190.875.564', 'A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical observation of dynamic cervical implant (DCI) internal fixation in the surgical treatment of cervical spondylosis]. | OBJECTIVE: To investigate the early clinical effects and radiological outcome of dynamic cervical implant (DCI) internal fixation in treating cervical spondylosis, and evaluate its safety and efficiency.METHODS: From June 2009 to December 2011, 19 patients with cervical spondylosis correspond to the indication of DCI i... | ['Adult', 'Cervical Vertebrae', 'Female', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Middle Aged', 'Prostheses and Implants', 'Range of Motion, Articular', 'Spondylosis'] | 25,638,898 | [['M01.060.116'], ['A02.835.232.834.151'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.695'], ['E01.370.600.700', 'G11.427.760'], ['C05.116.900.938']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Perivascular axillary brachial plexus block and patient positioning: the influence of a lateral, head-down position. | The aim of this study was to examine the effect of a 20 degrees Trendelenburg position on the blockade of nerves that exit the brachial plexus proximally in patients undergoing single-injection axillary brachial plexus block. After a pilot study of eight cadavers suggested that a head-down and lateral position would en... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anesthetics, Local', 'Arm', 'Brachial Plexus', 'Contrast Media', 'Female', 'Head-Down Tilt', 'Humans', 'Male', 'Mepivacaine', 'Middle Aged', 'Movement', 'Nerve Block', 'Radiography, Thoracic', 'Sensation', 'Supine Position', 'Thorax', 'Tomography, X-Ray Computed'] | 16,704,585 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['A01.378.800.075'], ['A08.800.800.720.050'], ['D27.505.259.500', 'D27.720.259'], ['G11.427.695.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rapid and automated substructure solution by Shake-and-Bake. | Direct methods of phase determination have played an important role in determining heavy-atom substructures from difference amplitudes of native-derivative crystal pairs or crystals containing anomalously scattering atoms. The minimal principle-based Shake-and-Bake procedure is one of the most successful direct methods... | ['Algorithms', 'Crystallography, X-Ray', 'Proteins', 'Software'] | 18,219,117 | [['G17.035', 'L01.224.050'], ['E05.196.309.742.225'], ['D12.776'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Olfactory identification deficits in first-episode psychosis may predict patients at risk for persistent negative and disorganized or cognitive symptoms. | OBJECTIVE: One-third of patients with a schizophrenia spectrum disorder have a measurable olfactory identification deficit at first examination. The authors studied the relationship of this deficit to symptom remission after 1 year of treatment.METHOD: Fifty-eight patients naive to antipsychotic medication who entered ... | ['Adult', 'Cognition Disorders', 'Comorbidity', 'Discrimination, Psychological', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Odorants', 'Olfaction Disorders', 'Outcome Assessment, Health Care', 'Psychiatric Status Rating Scales', 'Risk Factors', 'Schizophrenia', 'Schizophren... | 16,648,339 | [['M01.060.116'], ['F03.615.250'], ['N05.715.350.225', 'N06.850.490.687'], ['F02.463.593.257'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['G16.500.275.640', 'N06.230.480'], ['C10.597.751.600', 'C23.888.592.763.550'], ['H01.770.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
ATP release through connexin hemichannels in corneal endothelial cells. | PURPOSE: Intercellular Ca(2+) wave propagation is a distinct form of cell-cell communication. In corneal endothelial cells, intercellular Ca(2+) wave propagation evoked by a point mechanical stimulus (PMS) is partially mediated by adenosine triphosphate (ATP) release and subsequent activation of P2Y receptors. This stu... | ['Adenosine Triphosphate', 'Aniline Compounds', 'Animals', 'Calcium', 'Cattle', 'Cell Communication', 'Cells, Cultured', 'Connexin 26', 'Connexins', 'Endothelium, Corneal', 'Flufenamic Acid', 'Fluorescent Dyes', 'Gap Junctions', 'Ion Channels', 'Isoquinolines', 'Stress, Mechanical', 'Xanthenes'] | 15,790,881 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D02.092.146'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['G04.085'], ['A11.251'], ['D12.776.543.585.250.100'], ['D12.776.543.585.250'], ['A09.371.060.067.318', 'A09.371.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cadexomer iodine in ulcers colonised by Pseudomonas aeruginosa. | The clinical and bacteriological efficacy of topical cadexomer iodine on venous leg ulcers colonised with Pseudomonas aeruginosa was evaluated in an open, uncontrolled, multicentre pilot study. Nineteen patients with venous leg ulcers (median ulcer area 15.5 cm2) were treated with cadexomer iodine paste and short-stret... | ['Adult', 'Aged', 'Aged, 80 and over', 'Humans', 'Iodine Compounds', 'Iodophors', 'Leg Ulcer', 'Middle Aged', 'Pilot Projects', 'Pseudomonas Infections', 'Wound Healing', 'Wound Infection'] | 9,256,715 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.475'], ['D01.475.557'], ['C17.800.893.592'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['C01.150.252.400.739'], ['G16.762.891'], ['C01.947']... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bactericidal activity of streptomycin, isoniazid, rifampin, ethambutol, and pyrazinamide alone and in combination against Mycobacterium Tuberculosis. | Log-phase cultures of Mycobacterium tuberculosis in Tween-albumin medium were exposed to streptomycin, isoniazid, rifampin, ethambutol, and pyrazinamide in concentrations in the range likely to be present in serum during treatment of patients. The bactericidal activity of the drugs was measured as the decrease in viabl... | ['Drug Interactions', 'Drug Therapy, Combination', 'Ethambutol', 'Isoniazid', 'Microbial Sensitivity Tests', 'Mycobacterium tuberculosis', 'Pyrazinamide', 'Rifampin', 'Streptomycin'] | 411,404 | [['G07.690.773.968'], ['E02.319.310'], ['D02.092.782.258.368.265'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D03.383.679.750'], ['D03.633.400.811.700', 'D04.345.295.750.700'... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Potential Protective Effect of Achillea fragrantissima | Adriamycin (Adr) is a cytotoxic anthracycline agent that is utilized to manage many types of tumors, but its clinical use is undesirable due to severe cardiotoxicity. The present study aimed to investigate the cardioprotective effect of Achillea fragrantissima (A. fragrantissima) against Adr-induced cardiotoxicity thro... | ['Achillea', 'Animals', 'Antioxidants', 'Arrhythmias, Cardiac', 'Cardiotoxicity', 'Doxorubicin', 'Glutathione', 'Heart', 'Humans', 'Inflammation', 'Lipid Peroxidation', 'Rats', 'Signal Transduction'] | 31,317,032 | [['B01.650.940.800.575.912.250.100.037'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C14.280.067', 'C23.550.073'], ['C14.280.260', 'C23.550.161', 'C25.100.389', 'C26.733.266', 'G01.750.748.500.266'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcription of the lysine-2,3-aminomutase gene in the kam locus of Bacillus thuringiensis subsp. kurstaki HD73 is controlled by both ó54 and óK factors. | Lysine 2,3-aminomutase (KAM; EC 5.4.3.2) catalyzes the interconversion of l-lysine and l-â-lysine. The transcription and regulation of the kam locus, including lysine-2,3-aminomutase-encoding genes, in Bacillus thuringiensis were analyzed in this study. Reverse transcription-PCR (RT-PCR) analysis revealed that this loc... | ['Artificial Gene Fusion', 'Bacillus thuringiensis', 'Binding Sites', 'Gene Expression Regulation, Bacterial', 'Genes, Reporter', 'Intramolecular Transferases', 'Operon', 'Promoter Regions, Genetic', 'Protein Binding', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sigma Factor', 'Transcription Initiation Site', '... | 24,914,178 | [['E05.393.220.250'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['G02.111.570.120'], ['G05.308.300'], ['G05.360.340.024.340.435'], ['D08.811.399.520'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G02.111... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Irregular echogenic foci representing coagulation necrosis: a useful but perhaps under-recognized EUS echo feature of malignant lymph node invasion. | BACKGROUND AND AIMS: Coagulation necrosis has been described in malignant lymph nodes. Our aim was to determine if coagulation necrosis in mediastinal lymph nodes imaged by EUS could be used as a useful echo feature for predicting malignant invasion.METHODS AND DESIGN: Patients with known or suspected lung cancer who h... | ['Biopsy, Fine-Needle', 'Carcinoma, Non-Small-Cell Lung', 'Endosonography', 'False Positive Reactions', 'Humans', 'Lung Neoplasms', 'Lymph Nodes', 'Lymphatic Metastasis', 'Mediastinum', 'Necrosis', 'Predictive Value of Tests', 'Retrospective Studies', 'Sensitivity and Specificity'] | 19,565,048 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E01.370.350.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of the povidone-iodine (PVPI) in treatment of bacterial peritonitis induced in rats. | PURPOSE: To evaluate the effectiveness of the use of the povidone-iodine (PVI) added to the liquid of wash of the peritoneal cavity in the reduction of bacterial absorption and in the remainder non-phagocyted bacteria in the circulating blood of rat.METHODS: Thirty four Wistar females rats were used, distributed in the... | ['Animals', 'Anti-Infective Agents, Local', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Escherichia coli Infections', 'Female', 'Macrophages, Peritoneal', 'Peritoneal Cavity', 'Peritoneal Lavage', 'Peritonitis', 'Phagocytosis', 'Povidone-Iodine', 'Rats', 'Rats, Wistar', 'Solutions'] | 20,676,488 | [['B01.050'], ['D27.505.954.122.187'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.290.750', 'E05.337.550'], ['C01.150.252.400.310.330'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670.522.630', 'A15.382.680.397.630'], ['A01.923.047.025.600.678'], ['E05.927.705'], ['C01.463.600', 'C06.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli. | V8 protease, a member of the glutamyl endopeptidase I family, of Staphylococcus aureus V8 strain (GluV8) is widely used for proteome analysis because of its unique substrate specificity and resistance to detergents. In this study, an Escherichia coli expression system for GluV8, as well as its homologue from Staphyloco... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Catalytic Domain', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Immunoblotting', 'Molecular Sequence Data', 'Mutagenesis', 'Mutation', 'Protein Processing, Post-Translational', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Serine', 'Serine Endope... | 18,199,287 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.478.566.320', 'E05.601.470.320'], ['L01.453.245.667'], ['G05.558'], ['G05.365.590'], ['G02.111.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A Rare Cause of Male Infertility: 45,X/46,XY Mosaicism. | OBJECTIVE: To present the clinical, chromosomal, and endocrinological features of 8 infertile male cases with the 45,X/46,XY karyotype who were admitted to our infertility clinic.MATERIALS AND METHODS: The records of cases who were admitted to our infertility clinic between 1999 and 2015 were investigated. Eight cases ... | ['Adult', 'Azoospermia', 'Biopsy', 'Body Mass Index', 'Chromosomes, Human, X', 'Chromosomes, Human, Y', 'Humans', 'Infertility, Male', 'Karyotyping', 'Male', 'Mosaicism', 'Phenotype', 'Retrospective Studies', 'Semen', 'Semen Analysis', 'Sex Chromosome Aberrations', 'Testis'] | 29,161,714 | [['M01.060.116'], ['C12.294.365.700.380'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A11.284.187.520.300.325.680', 'A11.284... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of an intervening promoter nucleosome on gene expression. | Nucleosomes, which are the basic packaging units of chromatin, are stably positioned in promoters upstream of most stress-inducible genes. These promoter nucleosomes are generally thought to repress gene expression due to exclusion; they prevent transcription factors from accessing their target sites on the DNA. Howeve... | ['Acid Phosphatase', 'Binding Sites', 'DNA-Binding Proteins', 'Gene Expression Regulation, Fungal', 'Nucleosomes', 'Promoter Regions, Genetic', 'Protein Binding', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Transcription, Genetic'] | 23,700,413 | [['D08.811.277.352.650.025'], ['G02.111.570.120'], ['D12.776.260'], ['G05.308.330'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.360.160.180.625'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.679', 'G03.808'], ['B01.300.107.795.785.800', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Usefulness of semiquantitative analysis of dipyridamole-thallium-201 redistribution for improving risk stratification before vascular surgery. | Preoperative dipyridamole-thallium-201 scanning is sensitive in identifying patients prone to ischemic cardiac complications after vascular surgery, but most patients with redistribution do not have an event after surgery. Therefore, its positive predictive value is limited. To determine which patients with thallium re... | ['Aged', 'Coronary Disease', 'Dipyridamole', 'Female', 'Humans', 'Male', 'Middle Aged', 'Preoperative Care', 'Prognosis', 'Radionuclide Imaging', 'Retrospective Studies', 'Risk Factors', 'Thallium Radioisotopes', 'Vascular Surgical Procedures'] | 2,386,115 | [['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['D03.383.742.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795'], ['E01.789'], ['E01.370.350.710', 'E01.370.384.730'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluating the Relationship Between Participation in Student-Run Free Clinics and Changes in Empathy in Medical Students. | PURPOSE: We explored differences in changes in medical student empathy in the third year of medical school between volunteers at JeffHOPE, a multisite medical student-run free clinic of Sidney Kimmel Medical College (SKMC), and nonvolunteers.METHOD: Volunteerism and leadership experience at JeffHOPE were documented for... | ['Empathy', 'Humans', 'Student Run Clinic', 'Students, Medical', 'Volunteers', 'Vulnerable Populations'] | 28,033,737 | [['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.912'], ['M01.848.769.602'], ['M01.955'], ['M01.965']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A review of immune-related adverse events associated with immunotherapy]. | Immune checkpoint inhibitors have been approved for clinical application in China. However, the increased immune-related adverse event (irAE) needs more attention. This review summarized the incidence, characteristic clinical manifestation and treatment of irAEs associated with programmed cell death protein-1(PD-1) and... | ['China', 'Humans', 'Immunotherapy', 'Incidence', 'Neoplasms'] | 32,023,764 | [['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04']] | ['Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort: study protocol and results of the first 3 years of enrollment. | Although the etiologies of cardiovascular disease (CVD) are widely understood, the goal of finding a globally effective solution for preventing CVD is unrealistic. Therefore, we aimed to conduct a community-based prospective study on the prevention and management of CVD in Korean adults. This study was designed to recr... | ['Adult', 'Cardiovascular Diseases', 'Female', 'Health Status', 'Health Surveys', 'Humans', 'Male', 'Metabolic Diseases', 'Middle Aged', 'Population Surveillance', 'Prospective Studies', 'Risk Assessment', 'Risk Factors'] | 28,395,401 | [['M01.060.116'], ['C14'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452'], ['M01.060.116.630'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The Australian High and Low avoidance rat strains: differential effects of ethanol and alpha-methyl-p-tyrosine. | Two new lines of rats have been selectively bred for high or low active avoidance responding--the Australian High (AHA) and Low (ALA) Avoiders. Ethanol (1-1.5 g/kg body weight, i.p.) improved acquisition of active avoidance responding only in ALA, whereas alpha-methyl-p-tyrosine (AMPT; 80 mg/kg body weight, i.p.) seeme... | ['Animals', 'Arousal', 'Avoidance Learning', 'Escape Reaction', 'Ethanol', 'Female', 'Male', 'Methyltyrosines', 'Motor Activity', 'Rats', 'Rats, Inbred Strains', 'Reaction Time', 'Selection, Genetic', 'alpha-Methyltyrosine'] | 6,871,017 | [['B01.050'], ['F02.830.104', 'G11.561.035'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F01.145.113.780.688', 'F01.145.367', 'F01.145.875.439.500.688', 'G07.568.500.590.688', 'G11.427.410.568.850.688'], ['D02.033.375'], ['D12.125.072.050.875.485'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coronavirus-like particles in Aboriginals and non-Aboriginals in Western Australia. | Pleomorphic virus-like particles which resemble coronaviruses in morphology were found in faecal specimens from Aboriginal and non-Aboriginal children in Western Australia. They were equally prevalent in those with or without symptoms of diarrhoea. A much greater proportion of Aboriginal than non-Aboriginal children we... | ['Adult', 'Age Factors', 'Animals', 'Animals, Domestic', 'Australia', 'Child', 'Child, Preschool', 'Coronaviridae', 'Dogs', 'Feces', 'Gastroenteritis', 'Humans', 'Infant', 'Oceanic Ancestry Group'] | 661,689 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.116'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['M01.060.406.448'], ['B04.820.578.500.540'], ['B01.050.150.900.649.313.750.250.216.200'], ['A12.459'], ['C06.405.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Developing a pressure sore risk assessment scale. | Reliability of pressure sore risk has been found to be poor regardless of the scale used. Clear and unambiguous descriptions for each risk category are important. It is essential that people using assessment scales are familiar with them. | ['Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nursing Assessment', 'Nursing Evaluation Research', 'Pressure Ulcer', 'Reproducibility of Results', 'Risk Factors'] | 9,128,687 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.590.233.508.480'], ['H01.770.644.145.390.432', 'H02.478.395.432', 'N04.590.233.508.613.432'], ['C17.800.893.665'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ... | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Delusion formation and reasoning biases in those at clinical high risk for psychosis. | BACKGROUND: Cognitive models propose that faulty appraisal of anomalous experiences is critical in developing psychosis, particularly delusions. A data gathering bias may be fundamental to abnormal appraisal.AIMS: To examine whether there is a data gathering bias in people at high risk of developing psychosis.METHOD: I... | ['Adult', 'Delusions', 'Humans', 'Impulsive Behavior', 'Intelligence', 'Judgment', 'Memory, Short-Term', 'Neuropsychological Tests', 'Problem Solving', 'Psychiatric Status Rating Scales', 'Psychotic Disorders'] | 18,055,936 | [['M01.060.116'], ['F01.145.126.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F01.752.543'], ['F02.463.785.626'], ['F02.463.425.540.407'], ['F04.711.513'], ['F02.463.425.725', 'F02.463.785.810'], ['F04.711.513.653'], ['F03.700.675']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel method of demonstrating the molecular and functional equivalence between in vitro and plant-produced double-stranded RNA. | A biotechnology-derived corn variety, MON 87411, containing a suppression cassette that expresses an inverted repeat sequence that matches the sequence of western corn rootworm (WCR; Diabrotica virgifera virgifera) has been developed. The expression of the cassette results in the formation of a double-stranded RNA (dsR... | ['Animals', 'Coleoptera', 'Dose-Response Relationship, Drug', 'Insect Control', 'Pest Control, Biological', 'Plant Roots', 'Plants, Genetically Modified', 'RNA, Double-Stranded', 'Zea mays'] | 26,361,852 | [['B01.050'], ['B01.050.500.131.617.720.500.500.375'], ['G07.690.773.875', 'G07.690.936.500'], ['N06.850.780.200.650.425'], ['N06.850.780.200.650.650'], ['A18.400'], ['B01.650.520', 'B05.620.600'], ['D13.444.735.490', 'G02.111.570.820.486.775', 'G05.360.580.775'], ['B01.650.940.800.575.912.250.822.966']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Central glucocorticoid regulation of parasympathetic drive to pancreatic B-cells in the obese fa/fa rat. | The effects of glucocorticoids on the insulin secretory response to an intravenous glucose load have been studied in lean (Fa/?) and obese fa/fa Zucker rats. The role of parasympathetic drive to the pancreatic B-cells was assessed as that component of the insulin secretory response that was blocked by pretreatment of t... | ['Adrenalectomy', 'Animals', 'Blood Glucose', 'Brain', 'Glucocorticoids', 'Insulin', 'Insulin Resistance', 'Islets of Langerhans', 'Male', 'Obesity', 'Parasympathetic Nervous System', 'Rats', 'Rats, Zucker', 'Receptors, Glucocorticoid', 'Vagus Nerve'] | 1,938,098 | [['E04.270.115'], ['B01.050'], ['D09.947.875.359.448.500'], ['A08.186.211'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['A03.734.414', 'A06.300.414'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Notable radiophysicists and radiochemists in Croatia by 1945]. | Physicists and chemists were among the first potential victims of occupational exposure to ionising radiation and they were also the first to warn about the harmful effects of radiation on living organisms. This review presents the work of the first notable scientists in the field of radiation science in Croatia from t... | ['Croatia', 'Health Physics', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Radiochemistry'] | 21,971,113 | [['Z01.542.248.295'], ['H01.671.368', 'H02.229.333'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.181.529.776']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Recognising facial surfaces. | The extent to which faces depicted as surfaces devoid of pigmentation and with minimal texture cues ('head models') could be matched with photographs (when unfamiliar) and identified (when familiar) was examined in three experiments. The head models were obtained by scanning the three-dimensional surface of the face wi... | ['Adolescent', 'Adult', 'Aged', 'Face', 'Female', 'Head', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Pattern Recognition, Visual', 'Recognition, Psychology', 'Young Adult'] | 24,601,032 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A01.456.505'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.116.630'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.425.540.706'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Patterns of genetic variation in native grape phylloxera on two sympatric host species. | Random amplified polymorphic DNA (RAPD) markers were used to examine population genetic structure in populations of native grape phylloxera. This research asked: (i) do RAPD markers distinguish two groups corresponding to the two host plant species; and (ii) do RAPD markers distinguish groups according to spatial locat... | ['Animals', 'Cluster Analysis', 'Genes, Insect', 'Genetic Variation', 'Hemiptera', 'Missouri', 'Polymorphism, Genetic', 'Random Amplified Polymorphic DNA Technique', 'Rosales'] | 10,792,695 | [['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G05.360.340.024.340.340', 'G05.360.340.357.500'], ['G05.365'], ['B01.050.500.131.617.412'], ['Z01.107.567.875.510.515'], ['G05.365.795'], ['E05.393.620.500.687', 'E05.601.700'], ['B01.650.940.800.575.912.250.859.937']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Does bruising help determine which fractures are caused by abuse? | To determine whether the presence or absence of bruising can be used to differentiate between abusive and nonabusive fractures, a retrospective study was conducted of patients with acute fractures referred to a child abuse team. A bruise and fracture were considered associated if both occurred on the same body site. Ch... | ['Causality', 'Chicago', 'Child Abuse', 'Child, Preschool', 'Contusions', 'Cross-Sectional Studies', 'Diagnosis, Differential', 'Female', 'Fractures, Bone', 'Humans', 'Infant', 'Male', 'Referral and Consultation', 'Retrospective Studies'] | 19,001,359 | [['N05.715.350.200', 'N06.850.490.625'], ['Z01.107.567.875.350.350.200', 'Z01.107.567.875.510.350.200', 'Z01.433.305'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.060.406.448'], ['C26.974.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.171'], ['C26.404'], [... | ['Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Long-term survival in 2 cases with unresectable hilar bile duct cancer and sclerosing cholangitis]. | Case 1: A 69-year-old man was admitted to a nearby clinic due to upper abdominal pain. Computed tomography revealed stenosis of the hilar bile duct and dilation of the intrahepatic bile duct in both lobes of the liver. A percutaneous transhepatic biliary drainage tube was inserted in the right anterior segment branch, ... | ['Aged', 'Antimetabolites, Antineoplastic', 'Bile Duct Neoplasms', 'Cholangitis, Sclerosing', 'Deoxycytidine', 'Female', 'Humans', 'Male', 'Time Factors', 'Treatment Outcome'] | 23,267,997 | [['M01.060.116.100'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['C06.130.120.200.110'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins. | We have analyzed histone acetylation at the steroid-responsive mouse mammary tumor virus (MMTV) promoter in five separate cell lines that express functional glucocorticoid and/or progesterone receptors. Chromatin immunoprecipitation assays reveal that glucocorticoid and progesterone receptors bind the MMTV promoter aft... | ['Acetylation', 'Animals', 'CREB-Binding Protein', 'Chromatin', 'Gene Expression Regulation', 'Histones', 'Mammary Tumor Virus, Mouse', 'Mice', 'Nuclear Proteins', 'Promoter Regions, Genetic', 'Protein Binding', 'Receptors, Glucocorticoid', 'Receptors, Progesterone', 'Trans-Activators', 'Transcription, Genetic', 'Trans... | 12,637,584 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['D08.811.913.050.134.415.500.575.249', 'D12.776.930.680.300'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['G05.308'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B04.613.807.124.500', 'B04... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RPE65 is highly uveitogenic in rats. | PURPOSE: To examine the hypothesis that RPE65, a protein specific to the retinal pigment epithelium, is uveitogenic in rats.METHODS: Rats of four inbred strains (Lewis, Brown Norway, Fischer, and SHR) were immunized with native or recombinant bovine RPE65, or with S-antigen (S-Ag), emulsified with complete Freund adjuv... | ['Animals', 'Autoimmune Diseases', 'Carrier Proteins', 'Electrophoresis, Polyacrylamide Gel', 'Eye Proteins', 'Immunization', 'Male', 'Pigment Epithelium of Eye', 'Proteins', 'Rats', 'Rats, Inbred BN', 'Rats, Inbred F344', 'Rats, Inbred Lew', 'Rats, Inbred SHR', 'Recombinant Proteins', 'Uveitis', 'cis-trans-Isomerases'... | 12,091,425 | [['B01.050'], ['C20.111'], ['D12.776.157'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.306'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['A09.371.670', 'A10.272.640'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.52... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Visual-manual tracking and vestibular function during 7-day dry immersion]. | The seven-day DI experiment provided an opportunity to study the effects of decreased proprioceptive, tactile and support afferentation on the vestibular function and visual-manual tracking. Before and after immersion, six subjects participated in videooculographic evaluation of the static torsion otolith-cervicoocular... | ['Adult', 'Electrooculography', 'Eye Movements', 'Follow-Up Studies', 'Gravity Sensing', 'Head Movements', 'Humans', 'Immersion', 'Male', 'Oculomotor Muscles', 'Otolithic Membrane', 'Reference Values', 'Reflex, Vestibulo-Ocular', 'Vestibule, Labyrinth', 'Young Adult'] | 19,192,531 | [['M01.060.116'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['G11.427.410.140', 'G14.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G11.561.790.255', 'G15.375'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.466'], ['A02.633.56... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Picosecond absorption studies on rhodopsin and isorhodopsin in detergent and native membrane. | Picosecond transient absorption spectra of rhodopsin and isorhodopsin were measured at room temperature with a double-beam laser spectrophotometer after excitation at 355 nm. Photolysis studies were performed on rhodopsin solubilized in two different detergents (digitonin and 3-[(3-cholamidopropyl)dimethylammonio]-1-pr... | ['Animals', 'Cattle', 'Cell Membrane', 'Cholic Acids', 'Digitonin', 'Isomerism', 'Light', 'Photolysis', 'Retinal Pigments', 'Rhodopsin', 'Rod Cell Outer Segment', 'Solubility', 'Spectrophotometry'] | 6,487,580 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.149'], ['D04.210.500.105.225', 'D04.210.500.221.430'], ['D04.210.500.155.580.130.500.236', 'D09.408.180.261.236'], ['G02.111.570.685', 'G02.607.445'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G02.740.685'], ['D23.767... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thin film processing using S-layer proteins: biotemplated assembly of colloidal gold etch masks for fabrication of silicon nanopillar arrays. | We explored the bionanofabrication of silicon nanopillar structures using ordered gold nanoparticle arrays generated from microbial surface layer (S-layer) protein templates. The S-layer template used for these thin film processing experiments was isolated from the Gram-positive bacterium Deinococcus radiodurans. In th... | ['Colloids', 'Gold', 'Microscopy, Electron, Scanning', 'Nanostructures', 'Proteins', 'Silicon'] | 17,324,560 | [['D20.280', 'D26.255.165'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.637.512'], ['D12.776'], ['D01.268.513.937']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of presolvent extraction processing method on the nutritional value of soybean meal for chicks. | This study evaluated the effect of extruding or expander processing prior to solvent extraction on the nutritional value of soybean meal (SBM). Three samples of SBM containing 100% nonexpander SBM, 100% expander SBM, or a mixture of nonexpander and expander SBM were obtained from a commercial plant. An experiment was c... | ['Amino Acids', 'Animal Feed', 'Animals', 'Chickens', 'Food Handling', 'Glutens', 'Male', 'Nutritive Value', 'Solvents', 'Soybeans', 'Weight Gain', 'Zea mays'] | 11,092,336 | [['D12.125'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['J01.576.423.200'], ['D12.776.765.433.500.500', 'D12.776.765.725.500.500'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['D27.720.844'], ['B01.650.940.800.575.91... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Is screening for vascular disease a valuable proposition? | The value of health screening among the general population has been well-documented, with testing for hypertension, diabetes, and glaucoma now commonplace. It was the purpose of our study to determine the efficacy of a screening program for peripheral vascular disease and carotid artery disease using the noninvasive la... | ['Adolescent', 'Adult', 'Ankle', 'Arm', 'Blood Pressure', 'Blood Pressure Determination', 'Carotid Arteries', 'Carotid Artery Diseases', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Risk Factors', 'Ultrasonography', 'Vascular Diseases'] | 3,288,641 | [['M01.060.057'], ['M01.060.116'], ['A01.378.610.050'], ['A01.378.800.075'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chronic necrotising aspergillosis mimicking ACTH-secreting tumour in a case of Cushing's disease. | An 18-year-old man presenting with speech and behaviour disorders was found to suffer from Cushing's syndrome. Ectopic ACTH secretion was initially suspected on the basis of very high cortisoluria and ACTH concentrations, severe hypokalemia, a lung hypermetabolic lesion and a normal pituitary on conventional magnetic r... | ['ACTH Syndrome, Ectopic', 'Adolescent', 'Chronic Disease', 'Diagnosis, Differential', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Necrosis', 'Petrosal Sinus Sampling', 'Pituitary ACTH Hypersecretion', 'Pulmonary Aspergillosis'] | 23,967,728 | [['C04.730.713.317'], ['M01.060.057'], ['C23.550.291.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C23.550.717'], ['E01.370.225.124.100.600', 'E01.370.225.998.110.600', 'E04.665.150.600', 'E05.200.124.100.600', 'E05.200.998.110.600'], ['C10.228.140.617.738.250.725', 'C1... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
What information should lead to a suspicion of catheter sepsis in HPN? | BACKGROUND & AIMS: The diagnosis of catheter sepsis in patients on home parenteral nutrition can be difficult and patients often do not present with classical symptoms of pyrexia whilst feeding. This study reviews the clinical and diagnostic criteria needed to diagnose catheter sepsis.METHODS: A retrospective consecuti... | ['Bilirubin', 'C-Reactive Protein', 'Catheterization, Central Venous', 'Catheters, Indwelling', 'Diagnosis, Differential', 'Equipment Contamination', 'Humans', 'Leukocyte Count', 'Liver Function Tests', 'Parenteral Nutrition, Home', 'Predictive Value of Tests', 'ROC Curve', 'Retrospective Studies', 'Sepsis', 'Serum Alb... | 18,662,842 | [['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E07.132.500'], ['E01.171'], ['N06.850.540'], ['B01.050.150.900.649.313.988... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Use of echography for diagnosing aldosteromas]. | Altogether 23 patients were examined to assess the value of echography in the diagnosis of aldosteromas. Tumors were diagnosed at operation in 21 (2 malignant tumors) and adrenal hyperplasia in 2. The accuracy of diagnosis with regard to the presence or absence of aldosteromas was 82.6%. An analysis of the causes of er... | ['Adolescent', 'Adrenal Gland Neoplasms', 'Adrenocortical Hyperfunction', 'Adult', 'Diagnostic Errors', 'Humans', 'Hyperaldosteronism', 'Middle Aged', 'Ultrasonography'] | 3,909,477 | [['M01.060.057'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['C19.053.800'], ['M01.060.116'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.053.800.604'], ['M01.060.116.630'], ['E01.370.350.850']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using convolutional neural networks to estimate time-of-flight from PET detector waveforms. | Although there have been impressive strides in detector development for time-of-flight positron emission tomography, most detectors still make use of simple signal processing methods to extract the time-of-flight information from the detector signals. In most cases, the timing pick-off for each waveform is computed usi... | ['Electronics', 'Electrons', 'Equipment Design', 'Humans', 'Machine Learning', 'Neural Networks, Computer', 'Positron-Emission Tomography', 'Scintillation Counting', 'Signal-To-Noise Ratio'] | 29,182,151 | [['H01.671.293'], ['G01.249.335', 'G01.358.500.750'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['G17.485', 'L01.224.050.375.605'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.825.800.399', 'E01.370.38... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
The evaluation of exposure risks for natural transmission of scrapie within an infected flock. | BACKGROUND: Although the epidemiology of scrapie has been broadly understood for many years, attempts to introduce voluntary or compulsory controls to eradicate the disease have frequently failed. Lack of precision in defining the risk factors on farm has been one of the challenges to designing control strategies. This... | ['Animals', 'Environmental Exposure', 'Female', 'Pregnancy', 'Proportional Hazards Models', 'Risk Factors', 'Scrapie', 'Sheep', 'Survival Analysis', 'Time Factors'] | 19,818,127 | [['B01.050'], ['N06.850.460.350'], ['G08.686.784.769'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.835.900', 'N05.715.360.750.530.650', 'N05.715.360.750.625.650', 'N05.715.360.750.695.650', 'N05.715.360.750.795.825', 'N06.850.520.830.500.700', 'N06.850.520.830.... | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The distribution and frequency of oral veillonella spp. in the tongue biofilm of healthy young adults. | Five species of oral Veillonella, V. atypica, V. denticariosi, V. dispar, V. parvula, and V. rogosae, have been suggested to be early colonizers of dental biofilm and causes of opportunistic infections and oral malodor. However, the pathogenicity and the distribution of oral Veillonella spp. have not been clarified. Pr... | ['Biofilms', 'DNA Primers', 'Female', 'Humans', 'Male', 'Polymerase Chain Reaction', 'Species Specificity', 'Tongue', 'Veillonella', 'Young Adult'] | 21,850,474 | [['A20.593', 'G06.120'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500'], ['G16.824'], ['A03.556.500.885', 'A14.549.885'], ['B03.440.425.410.800.938'], ['M01.060.116.815']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessment of risk factor variants of LRRK2, MAPT, SNCA and TCEANC2 genes in Hungarian sporadic Parkinson's disease patients. | INTRODUCTION: Parkinson's disease is the second most common neurodegenerative disease. Lifestyle, environmental effects and several genetic factors have been proposed to contribute to its development. Though the majority of PD cases do not have a family history of disease, genetic alterations are proposed to be present... | ['Adult', 'Aged', 'Alleles', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Hungary', 'Leucine-Rich Repeat Serine-Threonine Protein Kinase-2', 'Male', 'Middle Aged', 'Parkinson Disease', 'Polymorphism, Single Nucleotide', 'alpha-Synuclein', 'tau Proteins'] | 31,085,292 | [['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['D08.811.913.696.620.682.700.534', 'D12.776.637.750'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.66... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The developing discipline of nursing from a Dutch perspective. | This article is based on a literature review and presents an overview of the development of nursing from vocation to a science based profession. It first addresses the start of formal nursing education in The Netherlands and then focuses on the developing academic discipline, which originated in the U.S.A. While the ma... | ['Education, Nursing', 'Education, Nursing, Baccalaureate', 'Education, Nursing, Graduate', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Netherlands', 'Nursing Research', 'Professional Practice'] | 1,612,840 | [['I02.358.462'], ['I02.358.462.316'], ['I02.358.337.450', 'I02.358.462.565'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.651'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['N04.452.758']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Sampling framework for accurate curvature estimation in discrete surfaces. | Accurate curvature estimation in discrete surfaces is an important problem with numerous applications. Curvature is an indicator of ridges and can be used in applications such as shape analysis and recognition, object segmentation, adaptive smoothing, anisotropic fairing of irregular meshes, and anisotropic texture map... | ['Algorithms', 'Computer Graphics', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Information Storage and Retrieval', 'Sample Size', 'Signal Processing, Computer-Assisted'] | 16,144,254 | [['G17.035', 'L01.224.050'], ['L01.224.108', 'L01.296.110'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['L01.313.500.750.280', 'L01.470'], ['E05.318.370.762', 'E05.581.500.902', 'N05.715.360.325.692', 'N06.850.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Thermogravimetric and decomposition kinetic studies of Mesua ferrea L. deoiled cake. | The present study aims to explore the physico-chemical properties of Mesua ferrea L. (Iron wood tree) deoiled cake (MFDC) and decomposition parameters for thermochemical methods of conversion. The physico-chemical characteristics of MFDC were investigated by bomb calorimetry, TG/DTA (10, 20 and 40°C min(-1)), elemental... | ['Kinetics', 'Malpighiaceae', 'Models, Chemical', 'Plant Oils', 'Regression Analysis', 'Temperature', 'Thermogravimetry', 'Waste Products'] | 23,644,072 | [['G01.374.661', 'G02.111.490'], ['B01.650.940.800.575.912.250.859.797.690'], ['E05.599.495'], ['D10.627.700', 'D20.215.784.750'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['E05.196... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Properties of neuroprotective cell-permeant Ca2+ chelators: effects on [Ca2+]i and glutamate neurotoxicity in vitro. | 1. Cell-permeant Ca2+ chelators such as 1,2-bis-(2-amino-phenoxy)ethane- N,N,N',N'-tetraacetic acid acetoxymethyl ester (BAPTA-AM) protect neurons against excitotoxic and ischemic neuronal injury in vitro and in vivo. Here we provide the first steps toward characterizing the mechanisms by which these agents produce the... | ['Animals', 'Calcium', 'Cell Survival', 'Cells, Cultured', 'Egtazic Acid', 'Fetus', 'Glutamic Acid', 'Mice', 'Nerve Degeneration', 'Neurons', 'Spinal Cord', 'Synaptic Transmission'] | 7,823,112 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.346'], ['A11.251'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['A16.378'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['C23.550.737'], ['A08.675', 'A11.671'], ['A08.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two novel alleles, HLA-B*46:01:11 and HLA-B*51:01:39 were identified in Chinese bone marrow donors. | HLA-B*46:01:11 has 219 G>A compared with HLA-B*46:01:01, and HLA-B*51:01:39 shows 561 G>A with HLA-B*51:01:01. | ['Alleles', 'Asian Continental Ancestry Group', 'Base Sequence', 'Bone Marrow Transplantation', 'Exons', 'Genotype', 'HLA-B Antigens', 'HLA-B51 Antigen', 'Histocompatibility Testing', 'Humans', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA', 'Tissue D... | 26,104,872 | [['G05.360.340.024.340.030'], ['M01.686.508.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G05.360.340.024.340.137.232'], ['G05.380'], ['D12.776.395.550.489.500', 'D12.776.543.550.439.500', 'D23.050.301.500.100.500', 'D23.050.301.500.450.380', 'D23.050.70... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
The name-letter-effect in groups: sharing initials with group members increases the quality of group work. | Although the name-letter-effect has been demonstrated reliably in choice contexts, recent research has called into question the existence of the name-letter-effect-the tendency among people to make choices that bear remarkable similarity with the letters in their own name. In this paper, we propose a connection between... | ['Adaptation, Physiological', 'Cooperative Behavior', 'Group Processes', 'Humans', 'Names', 'Quality Improvement', 'Task Performance and Analysis'] | 24,236,087 | [['G07.025', 'G16.012.500'], ['F01.145.813.115'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.400.556'], ['J01.293.754', 'N04.761.744'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Non-Orthogonal Random Access in MIMO Cognitive Radio Networks: Beamforming, Power Allocation, and Opportunistic Transmission. | We study secondary random access in multi-input multi-output cognitive radio networks, where a slotted ALOHA-type protocol and successive interference cancellation are used. We first introduce three types of transmit beamforming performed by secondary users, where multiple antennas are used to suppress the interference... | ['Algorithms', 'Artifacts', 'Cognition', 'Computer Communication Networks', 'Computer Simulation', 'Radio Waves', 'Wireless Technology'] | 28,076,402 | [['G17.035', 'L01.224.050'], ['E05.047'], ['F02.463.188'], ['L01.224.230.110'], ['L01.224.160'], ['G01.358.500.505.810', 'G01.750.250.810', 'G01.750.770.721'], ['L01.178.847.950']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Central nervous system toxicity associated with meperidine use in hepatic disease. | Meperidine-associated central nervous system (CNS) excitatory toxicities are believed to be caused by accumulation of the active metabolite normeperidine. Normeperidine is eliminated by the kidneys and accumulates in patients with renal insufficiency, sickle cell disease, and cancer. In patients with cirrhosis, the met... | ['Adult', 'Central Nervous System Diseases', 'Chronic Disease', 'Delirium', 'Hallucinations', 'Humans', 'Liver Cirrhosis', 'Male', 'Meperidine', 'Pancreatitis', 'Tremor'] | 8,197,046 | [['M01.060.116'], ['C10.228'], ['C23.550.291.500'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['D03.066.399.450', 'D03.3... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Weaning management of newly received beef calves with or without continuous exposure to a persistently infected bovine viral diarrhea virus pen mate: effects on health, performance, bovine viral diarrhea virus titers, and peripheral blood leukocytes. | Exposure to animals persistently infected (PI) with bovine viral diarrhea virus (BVDV) results in immunomodulation of cohorts that may have health and growth consequences; however, effects may differ in low-risk, preconditioned (PC) vs. high-risk, auction market (AM) beef cattle. Our objective was to compare health and... | ['Animal Husbandry', 'Animals', 'Antibodies, Viral', 'Body Weight', 'Bovine Respiratory Disease Complex', 'Bovine Virus Diarrhea-Mucosal Disease', 'Cattle', 'Diarrhea Virus 1, Bovine Viral', 'Diarrhea Virus 2, Bovine Viral', 'Infectious Disease Transmission, Vertical', 'Leukocytes', 'Male', 'Time Factors', 'Weaning'] | 22,648,754 | [['J01.040.090'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C01.748.085', 'C08.730.085', 'C22.196.090'], ['C01.925.782.350.675.106', 'C... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
March 2000: 5 month old boy with occipital bone mass. | A 5 month old boy was found by his mother to have a bony mass behind the left ear which extended intracranially on MRI scan. At surgery it was entirely extradural in location. Microscopically, a biphasic appearance consisting of large pigmented cells arranged into tubules and small nonpigmented basophilic cells arrange... | ['Humans', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Neuroectodermal Tumor, Melanotic', 'Occipital Bone', 'Skull Neoplasms'] | 10,764,053 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.350.825.500'], ['C04.557.465.625.630', 'C04.557.580.625.630'], ['A02.835.232.781.572'], ['C04.588.149.721', 'C05.116.231.754']] | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
AIDS and the WHO Collaborating Centres: memorandum from a WHO meeting. | The important role of WHO Collaborating Centres in international cooperation and action to control and prevent the acquired immunodeficiency syndrome (AIDS) in the affected countries, and eventually worldwide, was emphasized at a meeting in Geneva on 25-26 September 1985. The participants reviewed the progress that had... | ['Acquired Immunodeficiency Syndrome', 'Humans', 'Viral Vaccines', 'World Health Organization'] | 3,879,671 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899'], ['N03.540.514.718.800']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[First experiences with the new financing system and health care plans]. | Our experience on the new health reimbursement system and further plans for secondary care. The author gives a short review about the steps of the health reform emphasizing the importance of initiation of performance based reimbursement which has supported to reach the aims of our reform. The results of the new reimbur... | ['Health Care Reform', 'Health Promotion', 'Hungary', 'Insurance, Health, Reimbursement'] | 8,146,005 | [['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['I02.233.332.445', 'N02.421.726.407.579'], ['Z01.542.248.495'], ['N03.219.521.576.343.480', 'N03.219.521.710']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Fall prevalence in people with multiple sclerosis who use wheelchairs and scooters. | Falls are a serious health concern for persons with multiple sclerosis (PwMS) who use wheelchairs or scooters as their primary mode of mobility. Unfortunately, little is known about the fall prevalence and characteristics of this large segment of the multiple sclerosis (MS) community. The purpose of this study is to de... | ['Accidental Falls', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Georgia', 'Humans', 'Illinois', 'Israel', 'Male', 'Middle Aged', 'Mobility Limitation', 'Multiple Sclerosis', 'Prevalence', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Wheelchairs'] | 28,858,096 | [['N06.850.135.122'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.350', 'Z01.107.567.875.510.350'], ['Z01.252.245.500.375'], ['M01.060.116.630'], ['C23.888.550'], ['C10.114.3... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Systematic set-up errors for IMRT in the head and neck region: effect on dose distribution. | BACKGROUND AND PURPOSE: There is a general concern about intensity modulated radiation therapy (IMRT) treatments being more sensitive to patient positioning than conventional treatments. The aim of this study was to evaluate the International Commission on radiation units and measurements (ICRU) method for taking syste... | ['Head and Neck Neoplasms', 'Humans', 'Parotid Gland', 'Radiotherapy', 'Radiotherapy Dosage', 'Radiotherapy, Computer-Assisted', 'Spinal Cord'] | 12,742,270 | [['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['E02.815'], ['E02.815.639'], ['E02.815.635', 'L01.313.500.750.100.710.600'], ['A08.186.854']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Epigallocatechin gallate protects BEAS-2B cells from lipopolysaccharide-induced apoptosis through upregulation of gastrin-releasing peptide. | Gastrin-releasing peptide (GRP) plays a major role in the development and maintenance of lung epithelial cells by promoting cell division, whereas its suppression causes growth arrest and apoptosis. The present study shows that human bronchial epithelial BEAS-2B cells challenged with lipopolysaccharide (LPS), an endoto... | ['Apoptosis', 'Blotting, Western', 'Bronchi', 'Catechin', 'Cell Line', 'Gastrin-Releasing Peptide', 'Humans', 'Lipopolysaccharides', 'Real-Time Polymerase Chain Reaction', 'Up-Regulation'] | 28,432,554 | [['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A04.411.125'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['A11.251.210'], ['D06.472.317.410', 'D12.644.400.315', 'D12.7... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Construction of plasmid expression vector for specific peptide of the rubella virus E1 gene]. | OBJECTIVE: To construct a recombinant plasmid vector of the RV specific fragment for expressing the specific fragment of RV E1 protein.METHODS: RNA of the RV attenuated live vaccine Wistar RA27/3 strain was extracted and reversely transcribed. The specific fragment of the E1 gene was amplified and the PCR products clon... | ['Base Sequence', 'Cloning, Molecular', 'Gene Expression', 'Genetic Vectors', 'Molecular Sequence Data', 'Plasmids', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reaction', 'Rubella virus', 'Viral Envelope Proteins'] | 19,472,904 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['G05.297'], ['G05.360.337'], ['L01.453.245.667'], ['G05.360.600'], ['D13.444.735.828'], ['E05.393.620.500.725'], ['B04.820.578.875.700.700'], ['D09.400.430.968', 'D12.776.395.550.993', 'D12.776.543.550.993', 'D12.776.964.970.880']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The effect of gender on the physician's role. Attitudes and expectations of medical students examined by a questionnaire at the start of their studies]. | A questionnaire was given to 254 medical students matriculated in 1992/93 concerning their motivation for wanting to become a doctor, attitudes towards which qualities a doctor should have and their potential choice of medical specialty. The analysis focuses on whether answers are relation-orientated (i.e. directed tow... | ['Adult', 'Attitude of Health Personnel', 'Denmark', 'Female', 'Gender Identity', 'Humans', 'Interpersonal Relations', 'Male', 'Motivation', "Physician's Role", 'Sex Factors', 'Students, Medical', 'Surveys and Questionnaires'] | 7,676,529 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['Z01.542.816.124'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.658', 'F01.752.543.500.750'], ['F01.829.316.616.625.600'], ['N05.715.350.675', 'N06.850... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A new method for estimating HIV incidence from a single cross-sectional survey. | Estimating incidence from cross-sectional data sources is both important to the understanding of the HIV epidemic and challenging from a methodological standpoint. We develop a new incidence estimator that measures the size of the undiagnosed population and the amount of time spent undiagnosed in order to infer inciden... | ['Cross-Sectional Studies', 'Female', 'HIV Infections', 'Health Surveys', 'Humans', 'Incidence', 'Kenya', 'Male', 'Viral Load'] | 32,785,257 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Karyotype determination and gene mapping in two clinical isolates of Penicillium marneffei. | Electrophoretic karyotypes from two clinical isolates of Penicillium marneffei were derived using contoured-clamped homogeneous electric field (CHEF) gel electrophoresis. Five chromosome-sized DNA fragments were resolved from each isolate. Chromosomal length polymorphisms were evident among the three largest molecules.... | ['Chromosome Mapping', 'Chromosomes, Fungal', 'DNA, Fungal', 'Electrophoresis, Gel, Pulsed-Field', 'Fungal Proteins', 'Genes, rRNA', 'Humans', 'Karyotyping', 'Mycoses', 'Nucleic Acid Hybridization', 'Penicillium'] | 18,668,421 | [['E05.393.183'], ['A11.284.187.360', 'A19.311', 'G05.360.162.360'], ['D13.444.308.300'], ['E05.196.401.220', 'E05.301.300.220'], ['D12.776.354'], ['G05.360.340.024.340.645.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phylogeography and species boundaries of the western North American Nightsnake (Hypsiglena torquata): revisiting the subspecies concept. | The subspecies concept has received considerable debate throughout the past century. Subspecies were originally used to delineate potential incipient species, but were later employed to simply capture geographical variation. There is a recent trend to eliminate the trinomial in light of new evidence. Discrete, diagnosa... | ['Animals', 'Colubridae', 'DNA, Mitochondrial', 'Genetic Speciation', 'Geography', 'Molecular Sequence Data', 'North America', 'Phylogeny', 'Sequence Analysis, DNA', 'Species Specificity'] | 18,226,930 | [['B01.050'], ['B01.050.150.900.833.672.125.750'], ['D13.444.308.283.225'], ['G05.045.350', 'G16.075.350'], ['H01.277.500'], ['L01.453.245.667'], ['Z01.107.567'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700'], ['G16.824']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
Synthesis, characterization and in vitro inhibition of metal complexes of pyrazole based sulfonamide on human erythrocyte carbonic anhydrase isozymes I and II. | Sulfonamides represent an important class of biologically active compounds. A sulfonamide possessing carbonic anhydrase (CA) inhibitory properties obtained from a pyrazole based sulfonamide, ethyl 1-(3-nitrophenyl)-5-phenyl-3-((5-sulfamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazole-4-carboxylate (1), and its metal co... | ['Carbonic Anhydrase I', 'Carbonic Anhydrase II', 'Carbonic Anhydrase Inhibitors', 'Dose-Response Relationship, Drug', 'Erythrocytes', 'Humans', 'Isoenzymes', 'Metals, Heavy', 'Molecular Structure', 'Organometallic Compounds', 'Pyrazoles', 'Structure-Activity Relationship', 'Sulfonamides'] | 28,114,829 | [['D08.811.520.241.300.150.100'], ['D08.811.520.241.300.150.200'], ['D27.505.519.389.200'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['D01.268.556', 'D01.552.544'], ['G02.111.570', 'G02... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. | A murine monoclonal antibody specific for glycoprotein (GP)IIIa was prepared by immunization with a GPIIb- and GPIIIa-enriched Triton X-114 extract of platelet membranes. This antibody, designated AP-3, was shown by indirect immunoprecipitation to react solely with GPIIIa derived from either P1A1-positive or -negative ... | ['Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Binding Sites, Antibody', 'Binding, Competitive', 'Blood Platelets', 'Glycoproteins', 'Humans', 'Isoantigens', 'Membrane Proteins', 'Mice', 'Platelet Aggregation', 'Platelet Membrane Glycoproteins'] | 3,155,488 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.118.188', 'A15.145.229.188'], ['D09.400.430', 'D12.776.395'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control of a Candida glabrata prosthetic endovascular infection with posaconazole. | A 63-year-old man with a history of cirrhosis of the liver developed Candida glabrata fungemia after undergoing transjugular intrahepatic portosystemic shunt (TIPS) placement. Treatment with oral fluconazole was initially effective, but when the patient became neutropenic, subsequent blood cultures grew C. glabrata and... | ['Candida glabrata', 'Candidiasis', 'Drug Resistance, Fungal', 'Drug Therapy, Combination', 'Fluconazole', 'Humans', 'Male', 'Middle Aged', 'Portasystemic Shunt, Transjugular Intrahepatic', 'Triazoles'] | 16,702,108 | [['B01.300.107.795.095.400', 'B01.300.381.147.400', 'B01.300.930.176.400'], ['C01.150.703.160'], ['G06.225.383', 'G07.690.773.984.269.383'], ['E02.319.310'], ['D03.383.129.799.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.035.760.795', 'E04.100.814.868.937.830'], ['D03.383.129.799']... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The value of stress single photon emission computed tomography in patients without known coronary artery disease presenting with dyspnea. | BACKGROUND: Dyspnea is a complex system with multiple etiologies, including myocardial ischemia ("anginal equivalent"). Few studies have examined the utility of stress testing to detect coronary artery disease in this setting. The purpose of this study was to examine the prevalence, severity, and prognostic value of pe... | ['Aged', 'Coronary Artery Disease', 'Diagnosis, Differential', 'Dyspnea', 'Exercise Test', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Survival Analysis', 'Tomography, Emission-Computed, Single-Photon'] | 16,923,430 | [['M01.060.116.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.171'], ['C08.618.326', 'C23.888.852.371'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Steric zipper formed by hydrophobic peptide fragment of Syrian hamster prion protein. | Steric zippers, where the residues of two neighboring â-sheet layers are tightly interdigitated, have been proposed as fundamental structural units of amyloid fibrils by Eisenberg and co-workers. The steric zipper formed by polypeptides containing the palindromic sequence AGAAAAGA has a distinctive feature that the dis... | ['Amino Acid Sequence', 'Animals', 'Cricetinae', 'Mesocricetus', 'Microscopy, Electron, Transmission', 'Models, Molecular', 'Molecular Sequence Data', 'Nuclear Magnetic Resonance, Biomolecular', 'Peptide Fragments', 'Prions', 'Spectroscopy, Fourier Transform Infrared'] | 21,749,158 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['E05.599.595'], ['L01.453.245.667'], ['E05.196.867.519.550'], ['D12.644.541'], ['D12.776.785'], ['E05.196.712.726.676.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Exploring the charge nurse role: holding the frontline. | This study describes the experience of being a charge nurse in acute-care practice. The charge nurse role has become instrumental in achieving safe and effective outcomes. The role remains poorly defined with little focus on charge nurse development. This qualitative study used a descriptive exploratory method. Semistr... | ['Acute Disease', 'Adult', 'Aged', 'Clinical Competence', 'Decision Making', 'Female', 'Florida', 'Humans', 'Interviews as Topic', 'Leadership', 'Middle Aged', "Nurse's Role", 'Nursing, Supervisory', 'Patient Safety', 'Qualitative Research', 'Quality Assurance, Health Care'] | 23,100,000 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F02.463.785.373'], ['Z01.107.567.875.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.752.609'], ['M01.0... | ['Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Rationale, design and methodology for the Navajo Health and Nutrition Survey. | As recently as 1990, there was no reservation-wide, population-based health status information about Navajo Indians. To remedy this shortcoming, the Navajo Health and Nutrition Survey was conducted from 1991 to 1992 to assess the health and nutritional status of Navajo Reservation residents using a population-based sam... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Health Status', 'Health Surveys', 'Humans', 'Indians, North American', 'Male', 'Methods', 'Middle Aged', 'Nutrition Surveys', 'Research Design', 'Southwestern United States'] | 9,339,173 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['E05.581'], ['M01.060.116.630'], ['E05... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Controlling mesenchymal stem cells differentiate into contractile smooth muscle cells on a TiO2 micro/nano interface: Towards benign pericytes environment for endothelialization. | Building healthy and oriented smooth muscle cells (SMCs) environment is an effective method for improving the surface endothelialization of the cardiovascular implants. However, a long-term and stable source of SMCs for implantation without immune rejection and inflammation has not been solved, and mesenchymal stem cel... | ['AC133 Antigen', 'Actins', 'Calcium-Binding Proteins', 'Cell Differentiation', 'Cell Proliferation', 'Humans', 'Hyaluronan Receptors', 'Mesenchymal Stem Cells', 'Microfilament Proteins', 'Myocytes, Smooth Muscle', 'Pericytes', 'Titanium', 'X-Ray Diffraction', 'von Willebrand Factor'] | 27,232,304 | [['D12.776.395.550.007', 'D12.776.543.550.023'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D12.776.157.125'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The retinal nerve fiber layer of patients with neuromyelitis optica and chronic relapsing optic neuritis is more severely damaged than patients with multiple sclerosis. | BACKGROUND: To compare the retinal nerve fiber layer (RNFL) in eyes of patients with relapsing remitting multiple sclerosis (RRMS), neuromyelitis optica (NMO) and chronic relapsing inflammatory optic neuritis (CRION).METHODS: Evaluation of 62 patients with RRMS, NMO, and CRION in a cross-sectional study with spectral d... | ['Adult', 'Cross-Sectional Studies', 'Disease Progression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Neuromyelitis Optica', 'Optic Neuritis', 'Retina', 'Retinal Ganglion Cells', 'Tomography, Optical Coherence'] | 23,917,443 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['C10.114.375.600.500', 'C10.114.375.800', 'C10.292.700.550.500', 'C1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The influence of the diet with different content of magnesium on certain chemical and physical properties of the bones]. | The influence of the diet with different magnesium content on chosen chemical and physical properties of bones of young rats was investigated. In the first part of the work the influence of the calcium level in the diet on the content of magnesium and some other mineral constituents in bone was also studied. The invest... | ['Animals', 'Bone and Bones', 'Calcium', 'Calcium, Dietary', 'Diet', 'Female', 'Humans', 'Magnesium', 'Phosphorus', 'Rats', 'Rats, Inbred Strains', 'Tensile Strength'] | 7,349,395 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.146.395'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D01.268.666'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subacute myelo-optic neuropathy (SMON). First neuro-pathological report outside Japan. | A 72-year-old Caucasian woman developed degeneration of the spinal cord long tracts, polyneuropathy, and optic atrophy after chronic ingestion of clioquinol (200 mg/day) since she was 45. Diseases with a similar clinical picture, notably vitamin B12 deficiency (B12D), and subacute myelo-optic neuropathy (SMON), are dis... | ['Aged', 'Brain', 'Clioquinol', 'Demyelinating Diseases', 'Female', 'Humans', 'Nerve Degeneration', 'Nerve Fibers, Myelinated', 'Optic Atrophy', 'Optic Nerve', 'Spain', 'Spinal Cord', 'Spinal Cord Diseases'] | 6,460,092 | [['M01.060.116.100'], ['A08.186.211'], ['D03.633.100.810.350.625.400'], ['C10.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.737'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ['C10.292.700.225', 'C11.640.451'], ['A08.800.800.120.680'], ['Z01.542.846'], ['A08.186.854'], ['C10.228.854']] | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Multiple acute stroke syndrome: marker of embolic disease? | OBJECTIVE: To determine the frequency and etiologic significance of multiple acute ischemic lesions in stroke.BACKGROUND: Although patients may have more than one stroke during the course of their lives, acute ischemic stroke is usually thought of as a single event. Using diffusion-weighted imaging (DWI), an MRI techni... | ['Acute Disease', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Stroke', 'Syndrome'] | 10,680,802 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.228.140.300.775', 'C14.907.253.855'], ['C23.550.288.500']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Human breathing patterns in hypercapnia and hypoxia]. | In 3 young males with different types of breathing pattern, the responses of lung ventilation to hypercapnia and hypoxia were studied. Both kinds of the chemoreceptor activation of respiration increased the depth as well as the frequency of breathing. The subject with tachypnoic pattern of respiration responded to the ... | ['Adult', 'Carbon Dioxide', 'Humans', 'Hypercapnia', 'Hypoxia', 'Lung Volume Measurements', 'Male', 'Oxygen', 'Respiration', 'Time Factors'] | 6,409,678 | [['M01.060.116'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['C23.888.852.079'], ['E01.370.386.700.485'], ['D01.268.185.550', 'D01.362.670'], ['G09.772.705'], ['G01.910.857']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical presentation and natural history of chronic persistent hepatitis. A multicentre retrospective study on 1197 cases. | To obtain data on the clinical presentation and the course of the disease of biopsy-proven chronic persistent hepatitis (CPH), we coordinated a multicentre retrospective study on 1197 patients observed in 16 liver units throughout Italy from 1975 to 1985. Most patients were asymptomatic and CPH was often diagnosed eith... | ['Adolescent', 'Adult', 'Biopsy', 'Child', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Hepatitis B e Antigens', 'Hepatitis D', 'Hepatitis, Chronic', 'Humans', 'Italy', 'Liver', 'Liver Function Tests', 'Male', 'Middle Aged', 'Retrospective Studies'] | 1,742,503 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['M01.060.406'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.221.250.500', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Artery-to-artery embolism from a thrombus formed in stenotic middle cerebral artery. Report of an autopsy case. | The authors report an autopsy case with repeated transient ischemic attacks and subsequent strokes demonstrating evidence of artery-to-artery embolism from thrombi generated in the stenotic middle cerebral artery to the distal cortical branches. This case substantiates the existence of intracranial artery-to-artery emb... | ['Aged', 'Arterial Occlusive Diseases', 'Arteriosclerosis', 'Cerebral Angiography', 'Cerebral Arteries', 'Cerebrovascular Disorders', 'Constriction, Pathologic', 'Female', 'Humans', 'Intracranial Embolism and Thrombosis', 'Ischemic Attack, Transient'] | 3,590,260 | [['M01.060.116.100'], ['C14.907.137'], ['C14.907.137.126'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['A07.015.114.228'], ['C10.228.140.300', 'C14.907.253'], ['C23.300.287'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Memory impairment among primary care veterans. | Memory impairment is the most frequent cognitive dysfunction for older patients. Though studies have shown that dementia is often overlooked in primary care settings, there has been minimal focus specifically on memory impairment, on patients' concerns about memory, or their desire to address these concerns. The object... | ['Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Interviews as Topic', 'Los Angeles', 'Male', 'Memory Disorders', 'Primary Health Care', 'Veterans'] | 17,612,808 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.107.567.875.580.200.450', 'Z01.107.567.875.760.200.450', 'Z01.433.565'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Xanthine oxidase activity in bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease. | Chronic obstructive pulmonary disease (COPD) is a serious respiratory pathology characterized by irreversible limitation of expiratory flow and includes chronic obstructive bronchitis, chronic airflow limitation, and emphysema. To determine whether xanthine oxidase activity increased in the airspaces of COPD patients, ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bronchoalveolar Lavage Fluid', 'Cytochrome c Group', 'DNA', 'DNA Damage', 'Female', 'Humans', 'Kinetics', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Mutagens', 'Oxidation-Reduction', 'Spectrometry, Fluorescence', 'Superoxides', 'Uric Acid', 'Xanthine Oxidase'] | 8,818,629 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.927.100.500'], ['D08.244.286', 'D12.776.422.220.286'], ['D13.444.308'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['C08.381.495'], ['M01.060.116.630'], ['D27.888.569.468'], ['G02.700', 'G03.295.531'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
NCF1 (p47phox) and ncf1 pseudogenes are not associated with inflammatory bowel disease. | Crohn's disease (CD) and ulcerative colitis (UC) have a strong genetic component, contributing to a patient's susceptibility for inflammatory bowl disease (IBD). Linkage analysis has detected an IBD susceptibility locus in a region on chromosome 7q that encompasses the p47 (NCF1) gene and p47 (PsiNCF1) pseudogenes. Inv... | ['Case-Control Studies', 'Colitis, Ulcerative', 'Crohn Disease', 'DNA Primers', 'England', 'European Continental Ancestry Group', 'Genetic Predisposition to Disease', 'Humans', 'NADPH Oxidases', 'Phosphoproteins', 'Polymerase Chain Reaction', 'Pseudogenes'] | 15,626,894 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['Z01.542.363.300'], ['M01.686.508... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Primate vascular responses to octimibate, a non-prostanoid agonist at the prostacyclin receptor. | 1. Octimibate is a potent inhibitor of human platelet aggregation, and appears to act (at least in part) through the prostacyclin receptor, as described in the preceding paper. Here, the vascular effects, both in vitro and in vivo, of octimibate have been compared to those of the stable prostacyclin (PGI2) mimetic, ilo... | ['15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid', 'Adenosine Diphosphate', 'Animals', 'Blood Pressure', 'Dose-Response Relationship, Drug', 'Heart Rate', 'Hemodynamics', 'Humans', 'Imidazoles', 'In Vitro Techniques', 'Lung', 'Macaca fascicularis', 'Membranes', 'Muscle Relaxation', 'Muscle, Smooth, ... | 2,043,927 | [['D01.248.497.158.685.750.744.650.500.500', 'D01.339.431.374.744.650.500.500', 'D01.650.550.750.700.650.500.500', 'D02.389.338.638.650.500.500', 'D10.251.355.255.550.025.650.500.500', 'D23.469.050.175.725.025.650.500.500', 'D23.469.700.630.500'], ['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The temporal distribution of directional gradients under selection for an optimum. | Temporal variation in phenotypic selection is often attributed to environmental change causing movements of the adaptive surface relating traits to fitness, but this connection is rarely established empirically. Fluctuating phenotypic selection can be measured by the variance and autocorrelation of directional selectio... | ['Environment', 'Evolution, Molecular', 'Genetic Fitness', 'Models, Genetic', 'Selection, Genetic', 'Time Factors'] | 25,302,419 | [['G16.500.275', 'N06.230'], ['G05.045.250', 'G16.075.250'], ['G05.347'], ['E05.599.395.397'], ['G05.783'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Teicoplanin: Part 1. An evaluation of the concentrations seen in serum and the subcutaneous fat of the relatively ischaemic lower limb following a single intravenous bolus. | Teicoplanin is a new antibiotic currently undergoing clinical evaluation. Consecutive patients undergoing elective vascular surgery (n = 28) were randomised to receive a single intravenous bolus of 400 mg teicoplanin 1, 3, 6 or 12 h prior to surgery as prophylaxis against Gram-positive infection. Serum and fat antibiot... | ['Adipose Tissue', 'Anti-Bacterial Agents', 'Glycopeptides', 'Humans', 'Injections, Intravenous', 'Ischemia', 'Leg', 'Regional Blood Flow', 'Teicoplanin'] | 2,526,008 | [['A10.165.114'], ['D27.505.954.122.085'], ['D09.400.420', 'D12.644.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['C23.550.513'], ['A01.378.610.500'], ['G09.330.100.780'], ['D09.400.420.405.500', 'D12.644.233.352.500']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lipid hydroperoxide formation in the retina: correlation with retinal degeneration and light damage in a rat model of Smith-Lemli-Opitz syndrome. | The Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disease presenting with multiple congenital anomalies, caused by a defect in cholesterol biosynthesis that results in abnormally elevated levels of 7-dehydrocholesterol (7DHC). Progressive retinal degeneration has been demonstrated in a rat model of SLOS, ... | ['Animals', 'Light', 'Lipid Peroxides', 'Models, Animal', 'Rats', 'Rats, Sprague-Dawley', 'Retina', 'Retinal Degeneration', 'Smith-Lemli-Opitz Syndrome'] | 16,199,034 | [['B01.050'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D01.248.497.158.685.750.637', 'D01.339.431.374.637', 'D01.650.550.750.600', 'D02.389.338.450', 'D10.440'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A09.371.72... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SerpinB2 is critical to Th2 immunity against enteric nematode infection. | SerpinB2, a member of the serine protease inhibitor family, is expressed by macrophages and is significantly upregulated by inflammation. Recent studies implicated a role for SerpinB2 in the control of Th1 and Th2 immune responses, but the mechanisms of these effects are unknown. In this study, we used mice deficient i... | ['Animals', 'Cytokines', 'Gene Expression Regulation', 'Intestinal Mucosa', 'Intestines', 'Macrophages', 'Mice', 'Mice, Knockout', 'Monocytes', 'Muscle, Smooth', 'Nematode Infections', 'Plasminogen Activator Inhibitor 2', 'Th2 Cells'] | 23,630,350 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.308'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors responsible for the evolution of insulin resistance in Japanese type 2 diabetic patients: association with atherosclerosis. | Type 2 diabetes is a heterogeneous syndrome characterized by defective insulin secretion and/or insulin resistance. In distinct from Caucasian populations, Japanese type 2 diabetic patients are divided into two categories: one with insulin resistance and the other with normal insulin sensitivity. This unique feature al... | ['Adiponectin', 'Atherosclerosis', 'Body Mass Index', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Humans', 'Insulin Resistance', 'Japan', 'Leptin', 'Triglycerides'] | 17,532,086 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['C14.907.137.126.307'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Progressive effect of alpha-phenyl-N-tert-butyl nitrone (PBN) on rat embryo development in vitro. | In the present study we demonstrated the effects of the spin-trapping agent alpha-phenyl-N-tert-butylnitrone (PBN) on the in vitro development of rat embryos at the early stage. In rat embryos, PBN increased the speed of the first cleavage and had no toxicity during pregnancy after embryo culture. These results showed ... | ['Animals', 'Blastocyst', 'Culture Techniques', 'Cyclic N-Oxides', 'Embryonic and Fetal Development', 'Female', 'Free Radicals', 'Nitrogen Oxides', 'Pregnancy', 'Rats', 'Reactive Oxygen Species', 'Spin Labels', 'Superoxide Dismutase'] | 9,358,251 | [['B01.050'], ['A16.254.500'], ['E05.481.500'], ['D03.661.243'], ['G07.345.500.325', 'G08.686.784.170'], ['D01.339', 'D02.389'], ['D01.362.635', 'D01.625.550', 'D01.650.550.587'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.339.431', 'D01.650.775'], ['D02.389.678'], ['D08.811.682.881']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are large amounts of sodium stored in an osmotically inactive form during sodium retention? Balance studies in freely moving dogs. | Alterations in total body sodium (TBSodium) that covered the range from moderate deficit to large surplus were induced by 10 experimental protocols in 66 dogs to study whether large amounts of Na+ are stored in an osmotically inactive form during Na+ retention. Changes in TBSodium, total body potassium (TBPotassium), a... | ['Animals', 'Body Water', 'Body Weight', 'Bone and Bones', 'Dogs', 'Female', 'Osmolar Concentration', 'Potassium', 'Sodium', 'Sodium, Dietary', 'Tissue Distribution', 'Water-Electrolyte Balance'] | 16,373,433 | [['B01.050'], ['A12.207.200'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.649.313.750.250.216.200'], ['G02.640'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D0... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Validation of BREV: comparison with reference battery in 173 children with learning disorders]. | INTRODUCTION: The BREV battery (Battery for rapid evaluation of cognitive functions) is a tool which can be used for the rapid neuropsychological evaluation of children aged between 4 and 9 years.OBJECTIVES: After standardization (700 unaffected children) and validation by comparison with a reference battery (202 child... | ['Child', 'Child, Preschool', 'Female', 'Humans', 'Learning Disabilities', 'Male', 'Neuropsychological Tests', 'Predictive Value of Tests', 'Psychometrics', 'Reference Values', 'Sensitivity and Specificity'] | 16,271,450 | [['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['F04.711.513'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['F04.711.780'], ['E05.978.810'], ['E05.318.370.800', 'E05.318.740.87... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Epidemic investigation of diphtheria, Republic of Kazakhstan, 1990-1996. | The diphtheria epidemic that began in Russia in 1990 reached Kazakhstan in 1992 when 45 case-patients (a 50% increase over 1991) were reported. In 1993, 82 case-patients were reported, and 489 were reported in 1994. The epidemic peaked in 1995 when 1105 case-patients were reported (incidence rate=6.7/100,000 population... | ['Adolescent', 'Adult', 'Age Distribution', 'Child', 'Child, Preschool', 'Diphtheria', 'Diphtheria Toxoid', 'Diphtheria-Tetanus-Pertussis Vaccine', 'Disease Notification', 'Disease Outbreaks', 'Female', 'Humans', 'Immunization Programs', 'Incidence', 'Infant', 'Infant, Newborn', 'Kazakhstan', 'Male', 'Middle Aged', 'Va... | 10,657,198 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.410.040.246.388'], ['D20.215.894.691.263'], ['D20.215.894.135.535.300', 'D20.215.894.691.263.300', 'D20.215.894.691.824.300', 'D20.215.894.815.300'], ['E05.318.362', 'N06.850.520... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Subject-Specific Fully-Coupled and One-Way Fluid-Structure Interaction Models for Modeling of Carotid Atherosclerotic Plaques in Humans. | BACKGROUND: Hemodynamics play an important role in the development and progression of carotid atherosclerosis, and may be important in the assessment of plaque vulnerability. The aim of this study was to develop a system to assess the hemodynamics of carotid atherosclerotic plaques using subject-specific fluid-structur... | ['Adult', 'Aged', 'Carotid Arteries', 'Carotid Artery Diseases', 'Female', 'Healthy Volunteers', 'Hemodynamics', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Models, Cardiovascular', 'Plaque, Atherosclerotic'] | 26,510,514 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['M01.774.500', 'M01.955.236'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.599.395.161'], ['C23.300.823']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Improvement of dibenzothiophene desulfurization activity by removing the gene overlap in the dsz operon. | Dibenzothiophene (DBT) and its derivatives can be microbially desulfurized by Dsz enzymes. We investigated the expressional characteristics of the dsz operon. The result revealed that the ratio of mRNA quantity of dszA, dszB, and dszC was 11:3.3:1; however, western blot analysis indicated that the expression level of d... | ['Blotting, Western', 'Operon', 'Oxygenases', 'Plasmids', 'Protein Engineering', 'RNA, Messenger', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Rhodococcus', 'Sulfur', 'Thiophenes'] | 17,420,595 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['D08.811.682.690'], ['G05.360.600'], ['E05.393.420.601'], ['D13.444.735.544'], ['D12.776.828'], ['E05.393.620.500.725'], ['B03.510.024.981.775'], ['D01.268.185.900']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peripheral blood stem cell mobilisation by granulocyte-colony stimulating factor in patients with acute and old myocardial infarction for intracoronary cell infusion. | BACKGROUND/AIMS: Peripheral blood stem cells (PBSC) are one of the most promising stem cell sources for treatment of ischaemic heart disease. However, the experience of mobilisation and collection of PBSC using granulocyte-colony stimulating factor (G-CSF) in patients with myocardial infarction (MI) is still limited. W... | ['Acute Disease', 'Adult', 'Aged', 'Blood Component Removal', 'Chronic Disease', 'Feasibility Studies', 'Granulocyte Colony-Stimulating Factor', 'Hematopoietic Stem Cell Mobilization', 'Humans', 'Middle Aged', 'Myocardial Infarction', 'Stem Cell Transplantation'] | 19,460,773 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['E02.120'], ['C23.550.291.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.350', 'D23.529.374.410.240.350'], ['E02.095.410'], ['B01.050.150... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transmembrane TNF and IFNgamma induce caspase-independent death of primary mouse pancreatic beta cells. | Tumor necrosis factor (TNF) is important in the pathogenesis of autoimmune diabetes. It has an important role in immunological and inflammatory processes, and has also been shown to induce apoptotic cell death. We have shown that TNF + IFNgamma induce islet cell death in vitro. TNF exists as a biologically active trans... | ['Animals', 'Caspase 3', 'Caspases', 'Cell Death', 'Cell Line', 'In Vitro Techniques', 'Interferon-gamma', 'Islets of Langerhans', 'Mice', 'Mice, Inbred NOD', 'Tumor Necrosis Factor-alpha'] | 12,568,116 | [['B01.050'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.146'], ['A11.251.210'], ['E05.481'], ['D12.644.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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