Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[Intracellular interrelations of peripheral blood leukocytes in patients with different forms of chronic otitis media]. | Variations of the leukocyte count and leukocyte forms were investigated in patients with allergic diseases of the upper airways and middle ear. It was found that there was a discrepancy between the relative and absolute counts of various white blood cells. It was demonstrated mathematically that the counts of various w... | ['Chronic Disease', 'Eosinophils', 'Humans', 'Hypersensitivity', 'Leukocyte Count', 'Lymphocytes', 'Monocytes', 'Otitis Media', 'Sinusitis'] | 2,360,318 | [['C23.550.291.500'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.1... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arthroscopically assisted proximal extensor mechanism realignment of the knee. | An arthroscopically assisted proximal extensor mechanism realignment procedure has been designed and performed on 27 knees in 24 patients. The study group has been followed a minimum of 18 months. The procedure consists of a lateral retinacular release and an arthroscopically controlled plication of the medial patellar... | ['Adolescent', 'Adult', 'Arthroscopy', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Joint Dislocations', 'Joint Instability', 'Knee Joint', 'Male', 'Patella', 'Recurrence'] | 8,442,832 | [['M01.060.057'], ['M01.060.116'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['C05.550.521'], ['A02.835.583.475'], ['A... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A randomized, double-blind and placebo-controlled trial of modafinil in children and adolescents with attention deficit and hyperactivity disorder. | Attention-deficit/hyperactivity disorder (ADHD) is the most common behavioral disorder in childhood, with an estimated prevalence worldwide of 7%-17% among school-aged children. Modafinil is a centrally acting agent that is structurally and pharmacologically different from stimulants such as amphetamine and methylpheni... | ['Adolescent', 'Attention Deficit Disorder with Hyperactivity', 'Benzhydryl Compounds', 'Central Nervous System Stimulants', 'Child', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Modafinil', 'Psychiatric Status Rating Scales', 'Time Factors'] | 19,439,364 | [['M01.060.057'], ['F03.625.094.150'], ['D02.455.426.559.389.115'], ['D27.505.696.282', 'D27.505.954.427.220'], ['M01.060.406'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.115.550'], ['F04.711.513.653'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A rapid, accurate, immunohistochemical method to label proliferating cells in the digestive tract. A comparison with tritiated thymidine. | A rapid immunohistochemical method using 5'-bromo-2'-deoxyuridine (BrdU), a thymidine analog, for labeling proliferating epithelial cells was modified and tested for accuracy against standard tritiated thymidine autoradiography (3H-TdR) in rat esophagus, stomach, duodenum, and colon. Either BrdU or 3H-thymidine or both... | ['Animals', 'Bromodeoxyuridine', 'Cell Division', 'Digestive System', 'Esophagus', 'Immunohistochemistry', 'Male', 'Random Allocation', 'Rats', 'Rats, Inbred Strains', 'Thymidine', 'Time Factors'] | 1,983,830 | [['B01.050'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A03'], ['A03.556.875.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Pattern of diversity in the genomic region near the maize domestication gene tb1. | Domesticated maize and its wild ancestor (teosinte) differ strikingly in morphology and afford an opportunity to examine the connection between strong selection and diversity in a major crop species. The tb1 gene largely controls the increase in apical dominance in maize relative to teosinte, and a region of the tb1 lo... | ['Chromosomes, Artificial, Bacterial', 'Crops, Agricultural', 'Genes, Plant', 'Genetic Variation', 'Genome, Plant', 'Linkage Disequilibrium', 'Molecular Sequence Data', 'Phylogeny', 'Plant Proteins', 'Polymorphism, Genetic', 'Selection, Genetic', 'Species Specificity', 'Zea mays'] | 14,701,910 | [['A11.284.187.178.170', 'A11.284.187.190.170', 'A20.812.170', 'G05.360.162.178.170', 'G05.360.162.190.170', 'G05.360.337.249.170'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.365'], ['G05.360.340.365'], ['G05.348.500'], ['L01.453.245.667'], ['G05.697', ... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Index-matched indium tin oxide electrodes for capacitive touch screen panel applications. | Index-matched indium tin oxide (ITO) electrodes for capacitive touch screen panels have been fabricated to improve optical transmittance and reduce the difference of reflectance (deltaR) between the etched and un-etched regions. 8.5 nm Nb2O5 and 49 nm SiO2 thin films were deposited by magnetron sputtering as index-matc... | ['Electric Capacitance', 'Electrodes', 'Electronics', 'Equipment Design', 'Equipment Failure Analysis', 'Lighting', 'Nanostructures', 'Particle Size', 'Refractometry', 'Tin Compounds', 'Touch', 'User-Computer Interface'] | 24,245,328 | [['G01.358.500.249.270'], ['E07.305.250'], ['H01.671.293'], ['E05.320'], ['E05.325.192'], ['N06.230.150.410'], ['J01.637.512'], ['G02.712'], ['E05.196.808', 'H01.671.617.755'], ['D01.935'], ['F02.830.816.850', 'G11.561.790.850'], ['L01.224.900.910']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Temporal changes in the serum levels of gonadotrophins and testosterone in male rats bearing subcutaneous implants of 5 alpha-dihydrotestosterone. | This study has assessed the effect of s.c. implants of 5 alpha-dihydrotestosterone (DHT) on the blood levels of testosterone and gonadotrophins in intact and castrated adult male rats. The rats were bled via cardiac puncture at 1, 3, 7, 14, 21, 28, 35, 42, 49, 56, 63 and 70 days after DHT implantation. On days 28 and 4... | ['Animals', 'Dihydrotestosterone', 'Drug Implants', 'Drug Interactions', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Gonadotropins', 'Luteinizing Hormone', 'Male', 'Orchiectomy', 'Organ Size', 'Pituitary Gland', 'Prostate', 'Rats', 'Seminal Vesicles', 'Testosterone'] | 1,516,984 | [['B01.050'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['D26.255.210.315'], ['G07.690.773.968'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the beta T cell receptor gene in human lymphoblastic neoplasms. | DNA containing breakpoints of two different t(7;9) chromosomal translocations was cloned from the T lymphoblastic tumor cell lines SUP-T1 and SUP-T3. Sequence analysis of DNA from the t(7;9)(q34;q34.3) translocation of SUP-T1 revealed that chromosome 9 DNA had recombined with DNA 5' to rearranged D-J regions in the bet... | ['Chromosome Mapping', 'Chromosomes, Human, Pair 7', 'Chromosomes, Human, Pair 9', 'DNA Restriction Enzymes', 'DNA, Neoplasm', 'Humans', 'Leukemia, Lymphoid', 'Peptide Fragments', 'RNA, Messenger', 'RNA, Neoplasm', 'Receptors, Antigen, T-Cell', 'Receptors, Antigen, T-Cell, alpha-beta', 'Recombination, Genetic', 'T-Lymp... | 3,036,364 | [['E05.393.183'], ['A11.284.187.520.300.325.335', 'G05.360.162.520.300.325.335'], ['A11.284.187.520.300.325.345', 'G05.360.162.520.300.325.345'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cushing's disease: do patients remain dependent upon substitution therapy following microsurgical exstirpation of hypophyseal adenomas?]. | Data on 4 patients with Cushing's disease (2 microadenomas, 2 macroadenomas with chiasma syndromes) demonstrate that a few months after microsurgical extirpation of the pituitary adenoma (and, in macroadenomas, irradiation) the previously suppressed normal ACTH-producing cells recuperate and react adequately to stimula... | ['Adenoma', 'Adrenocorticotropic Hormone', 'Adult', 'Cushing Syndrome', 'Female', 'Follow-Up Studies', 'Gonadal Steroid Hormones', 'Humans', 'Male', 'Middle Aged', 'Pituitary Gland, Anterior', 'Pituitary Hormones', 'Pituitary Neoplasms'] | 6,302,834 | [['C04.557.470.035'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['C19.053.800.367'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', '... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Interaction between vitamin D receptor genotype and estrogen receptor alpha genotype influences vertebral fracture risk. | In view of the interactions of vitamin D and the estrogen endocrine system, we studied the combined influence of polymorphisms in the estrogen receptor (ER) alpha gene and the vitamin D receptor (VDR) gene on the susceptibility to osteoporotic vertebral fractures in 634 women aged 55 yr and older. Three VDR haplotypes ... | ['Aged', 'Bone Density', 'Estrogen Receptor alpha', 'Female', 'Genotype', 'Haplotypes', 'Humans', 'Middle Aged', 'Osteoporosis', 'Receptors, Calcitriol', 'Receptors, Estrogen', 'Reverse Transcriptase Polymerase Chain Reaction', 'Risk Factors', 'Spinal Fractures'] | 12,915,669 | [['M01.060.116.100'], ['G11.427.100'], ['D12.776.826.750.350.174'], ['G05.380'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.116.198.579', 'C18.452.104.579'], ['D12.776.826.535'], ['D12.776.826.750.350', 'D12.776.930.778.350'], ['E05.393.620.500.725'], ['E05.318.740.600.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acetylcarnitine formation during intense muscular contraction in humans. | To study the changes in carnitine during intense muscular effort subjects underwent 4 min intermittent electrical stimulation of the quadriceps femoris muscle and on a separate occasion performed 4 min exercise on a bicycle ergometer. Biopsies of the vastus lateralis muscle were taken at rest and after 2 and 4 min of s... | ['Acetylcarnitine', 'Adult', 'Carnitine', 'Electric Stimulation', 'Humans', 'Kinetics', 'Male', 'Muscle Contraction', 'Muscles'] | 3,624,147 | [['D02.092.877.883.099.090'], ['M01.060.116'], ['D02.092.877.883.099'], ['E05.723.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G11.427.494'], ['A02.633', 'A10.690']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhancement or inhibition of tumor growth by interferon: dependence on treatment protocol. | MSC cells are tumor cells originally induced in BALB/c mice by Moloney sarcoma virus. In these studies we demonstrated that, although these tumor cells are sensitive in vitro both to lysis by NK or NK-like cells and to the growth-inhibitory effect of murine L-cell interferon (IFN), the growth of the tumor in vivo could... | ['Animals', 'Cell Division', 'Cell Line', 'Interferon Type I', 'Killer Cells, Natural', 'L Cells', 'Mice', 'Moloney murine leukemia virus', 'Neoplasm Transplantation', 'Neoplasms', 'Sarcoma, Experimental', 'Whole-Body Irradiation'] | 6,360,916 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['A11.251.210.505', 'A11.329.228.505'], ['B01.050... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rare occurrence of occult hepatitis C virus in apparently uninfected injecting drug users: a two-centre, masked, case-control study. | Occult hepatitis C virus (HCV) is a phenomenon where serum HCV RNA is not detected by sensitive commercial assays, but viral RNA is detected by ultrasensitive techniques. Occult HCV infection has not previously been studied in highly exposed, but apparently uninfected (EU) individuals. Two studies examining occult infe... | ['Adult', 'Asymptomatic Diseases', 'Case-Control Studies', 'Female', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Leukocytes, Mononuclear', 'Longitudinal Studies', 'Male', 'Plasma', 'Prevalence', 'RNA, Viral', 'Substance Abuse, Intravenous', 'Young Adult'] | 24,010,647 | [['M01.060.116'], ['C23.550.291.187'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.14... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of a transcriptionally inactive p53 mutant by functional analysis of separated alleles in yeasts (FASAY) in a child osteosarcoma tumor: a case report. | Tumor suppressor gene p53 is one of the most specific genetic alterations occurring in osteosarcoma pathogenesis. It is thought to be an early and key step in the tumorigenesis of osteosarcoma. However, whether the p53 status is a marker predictive of response to therapy and a marker of prognostic value remains controv... | ['Child', 'Codon, Nonsense', 'DNA Mutational Analysis', 'Female', 'Humans', 'Loss of Heterozygosity', 'Mutation', 'Osteosarcoma', 'Tibia', 'Transcription, Genetic', 'Tumor Suppressor Protein p53'] | 15,205,094 | [['M01.060.406'], ['D13.444.735.544.355.250.235', 'G05.360.335.355.250.235', 'G05.365.590.195'], ['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.029.530'], ['G05.365.590'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ['A02.835.232.043.650.883'], ['G02.111.873', 'G05.297.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Emission of polycyclic aromatic hydrocarbons from indoor straw burning and emission inventory updating in China. | The emission factors for indoor straw combustion are a major data gap for estimating the polycyclic aromatic hydrocarbon (PAH) emissions in China. The emission factors for open-fire straw burning were borrowed from our previous study and a rough estimate was developed. As one of the most important emission sources in C... | ['Air Pollutants', 'China', 'Chromatography, Gas', 'Coke', 'Environmental Monitoring', 'Environmental Pollutants', 'Environmental Pollution', 'Equipment Design', 'Fires', 'Incineration', 'Poaceae', 'Polycyclic Aromatic Hydrocarbons', 'Smoke'] | 18,991,920 | [['D27.888.284.101'], ['Z01.252.474.164'], ['E05.196.181.349'], ['D20.345.108.110', 'N06.230.132.258.108.110'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['N06.850.460'], ['E05.320'], ['N06.230.216'], ['N06.850.860.510.900.600.500'], ['B01.650.940.800.575.912.250.822'], ['D02.455.426.559.847', 'D04.6... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Development and validation of a screening instrument to identify cardiometabolic predictors of mortality in older individuals with cancer: Secondary analysis of the Australian Longitudinal Study of Ageing (ALSA). | OBJECTIVE: The objective of this study was to identify significant cardiometabolic predictors of mortality among older cancer survivors and develop and validate a screening instrument to assess individual risk of mortality.MATERIALS AND METHODS: Retrospective cohort study used collected data from the ALSA. Cox proporti... | ['Aged', 'Aged, 80 and over', 'Blood Pressure', 'Body Mass Index', 'Cardiovascular Diseases', 'Early Detection of Cancer', 'Exercise', 'Female', 'Geriatric Assessment', 'Humans', 'Kaplan-Meier Estimate', 'Longitudinal Studies', 'Male', 'Metabolic Diseases', 'Neoplasms', 'Overweight', 'Retrospective Studies', 'Risk Asse... | 28,642,039 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['E01.390.500'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Characterization of the Saccharomyces cerevisiae FCY1 gene encoding cytosine deaminase and its homologue FCA1 of Candida albicans. | By functional complementation of a fcy1 null mutant of Saccharomyces cerevisiae, we have cloned and characterized the FCY1 gene, encoding cytosine deaminase in Saccharomyces cerevisiae, and its homologue FCA1, encoding cytosine deaminase in Candida albicans. Disruption of FCY1 resulted in high resistance to 5-fluorocyt... | ['Amino Acid Sequence', 'Candida albicans', 'Chromosome Mapping', 'Cloning, Molecular', 'Cytosine', 'Cytosine Deaminase', 'DNA, Fungal', 'Escherichia coli', 'Flucytosine', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Fungal', 'Gene Library', 'Genetic Complementation Test', 'Introns', 'Molecul... | 9,000,374 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['E05.393.183'], ['E05.393.220'], ['D03.383.742.698.421'], ['D08.811.277.151.486.625'], ['D13.444.308.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D03.383.742.698.421.431'], ['G05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The pallidosubthalamic projection: an anatomical substrate for nonmotor functions of the subthalamic nucleus in primates. | The subthalamic nucleus (STN) is the best target for correcting motor disability in parkinsonian patients with high-frequency stimulation. However, STN stimulation has also been reported to modify cognitive, emotional, and motivational functions. The aim of this study was to analyze the topographic organization of the ... | ['Animals', 'Biotin', 'Calbindins', 'Dextrans', 'Globus Pallidus', 'Immunohistochemistry', 'Male', 'Neural Pathways', 'Primates', 'S100 Calcium Binding Protein G', 'Subthalamic Nucleus', 'Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate'] | 15,382,210 | [['B01.050'], ['D03.383.129.308.080', 'D08.211.096'], ['D12.776.157.125.090'], ['D05.750.078.562.272', 'D09.698.365.272'], ['A08.186.211.200.885.287.249.487.397'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Low viral suppression and high HIV diagnosis rate among men who have sex with men with syphilis--Baltimore, Maryland. | BACKGROUND: The burden of syphilis and HIV among gay, bisexual, and other men who have sex with men (MSM) in Baltimore, Maryland, is substantial. Syphilis and HIV surveillance data were analyzed to characterize MSM with syphilis, including those with repeat infection and HIV coinfection, to strengthen prevention effort... | ['Adult', 'Baltimore', 'Bisexuality', 'Coinfection', 'Condoms', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Male', 'Mass Screening', 'Secondary Prevention', 'Sexual Behavior', 'Sexual Partners', 'Syphilis'] | 25,763,676 | [['M01.060.116'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['F01.145.802.975.200', 'G08.686.867.200'], ['C01.218'], ['E07.190.270.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light. | Green fluorescent protein (GFP) and GFP-like proteins represent invaluable genetically encoded fluorescent probes. In the last few years a new class of photoactivatable fluorescent proteins (PAFPs) capable of pronounced light-induced spectral changes have been developed. Except for tetrameric KFP1 (ref. 4), all known P... | ['Fluorescent Dyes', 'Light', 'Luminescent Proteins', 'Microscopy, Fluorescence, Multiphoton', 'Photochemistry', 'Protein Engineering'] | 16,550,175 | [['D27.720.233.348', 'D27.720.470.410.505.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D12.776.532'], ['E01.370.350.515.458.500', 'E01.370.350.515.717.250', 'E05.595.458.500', 'E05.595.717.250'], ['H01.181.529.711'], ['E05.393.420.601']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Family interaction and the development of borderline personality disorder: a transactional model. | Although no prospective epidemiological studies have evaluated the relationship between family interactions and the development of borderline personality disorder (BPD), there is considerable evidence for the central role of family interactions in the development of BPD. This paper describes the role of family interact... | ['Adolescent', 'Adult', 'Borderline Personality Disorder', 'Child', 'Conflict, Psychological', 'Empathy', 'Expressed Emotion', 'Family Relations', 'Humans', 'Internal-External Control', 'Object Attachment', 'Parenting', 'Risk Factors', 'Self Concept', 'Social Support', 'Transactional Analysis'] | 16,613,428 | [['M01.060.057'], ['M01.060.116'], ['F03.675.100'], ['M01.060.406'], ['F01.658.209'], ['F01.752.355', 'F01.752.543.500.500'], ['F01.829.197'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F02.739.794.624'], ['F01.829.263.370.310'], ['E05.318.740.600.800... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The development of the human placental villous tree. | The present investigation was undertaken in order to achieve a better understanding of the dynamics of placental villous differentiation. Villous trees from human placentas from different stages of pregnancy (first trimester to full term) were isolated and studied by light microscopy and scanning electron microscopy. F... | ['Cell Differentiation', 'Chorionic Villi', 'Female', 'Gestational Age', 'Humans', 'Microscopy, Electron, Scanning', 'Placentation', 'Pregnancy'] | 2,327,595 | [['G04.152'], ['A10.615.284.473.200', 'A16.254.750.473.200', 'A16.710.189'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G08.686.784.769.491'], ['G08.686.784.769']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental manipulation in the control of a zoonotic cutaneous leishmaniasis focus. | An investigation is currently underway to assess the efficiency and practicality of combined burrow destruction and removal of chenopods in the control of a zoonotic cutaneous leishmaniasis (ZCL) focus. Karameh and Sweimeh, situated in the southern Jordan Valley, are stable endemic foci for ZCL. Control measures have b... | ['Animals', 'Child', 'Child, Preschool', 'Environment', 'Gerbillinae', 'Humans', 'Infant', 'Jordan', 'Leishmaniasis, Cutaneous', 'Pilot Projects', 'Plants', 'Population Surveillance', 'Rodent Control', 'Skin Tests', 'Zoonoses'] | 7,802,493 | [['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.992.635.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.252.245.500.400'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.813.400', 'C17.800.838.775.560.400'], ['E05.318.... | ['Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Estimation of the full marginal costs of port related truck traffic. | NY region is expected to grow by additional 1 million people by 2020, which translates into roughly 70 million more tons of goods to be delivered annually. Due to lack of rail capacity, mainly trucks will haul this volume of freight, challenging an already much constrained highway network. What are the total costs asso... | ['Accidents, Traffic', 'Costs and Cost Analysis', 'Environment', 'Humans', 'Models, Econometric', 'Motor Vehicles', 'New Jersey', 'New York City', 'Ships', 'Transportation'] | 19,796,817 | [['N06.850.135.392'], ['N03.219.151'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.600.500', 'E05.599.835.890.500', 'N05.715.360.750.530.500.500', 'N06.850.520.830.500.600.500'], ['J01.937.500'], ['Z01.107.567.875.500.525'], ['Z01.107.567.875.350.530.530', 'Z01.107.567... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Association between parity and the risk for urinary incontinence in women: A meta-analysis of case-control and cohort studies. | Urinary incontinence (UI) is a common complaint for adult female. Cross-sectional studies suggested parity may link with UI, but the association between them was not well-established. We conducted a meta-analysis to investigate the association between parity and UI.Medline and Embase were searched for eligible case-con... | ['Adult', 'Case-Control Studies', 'Cohort Studies', 'Female', 'Humans', 'Middle Aged', 'Parity', 'Prevalence', 'Risk Factors', 'Urinary Incontinence'] | 29,995,798 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['E05.318.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Invasive urothelial carcinoma with chordoid features of the ureter: a rare entity and review of literature. | Invasive urothelial carcinoma (UC) is characterized by some histologic variants that can sometimes lead to diagnostic difficulty. In addition to those described by the World Health Organization. Recently invasive urothelial carcinoma with chordoid features (UCC) has been described as a distinct entity and there are rel... | ['Aged, 80 and over', 'Biomarkers, Tumor', 'Biopsy', 'Carcinoma', 'Female', 'Humans', 'Immunohistochemistry', 'Neoplasm Invasiveness', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Ureteral Neoplasms', 'Urothelium'] | 26,823,892 | [['M01.060.116.100.080'], ['D23.101.140'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Dietary silymarin improves removal of low density lipoproteins by the perfused rat liver. | Silymarin administered to the rats concurrently with high cholesterol diet normalized the high cholesterol diet-induced retardation of disappearance of low density lipoproteins (LDL) from the medium during recirculating perfusion of livers from these rats. We suggest that the improvement of LDL removal by the liver aft... | ['Animals', 'Anticholesteremic Agents', 'Cholesterol, Dietary', 'Female', 'Lipoproteins, LDL', 'Liver', 'Rats', 'Rats, Wistar', 'Silymarin'] | 9,684,480 | [['B01.050'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['D10.532.515', 'D12.776.521.550'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D03.383.663.283.266.450.268.77... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the effect of various antisera and cobra venom factor on inflammatory reactions in guinea-pig skin. II. The Arthus reaction and the local Shwartzman reaction. | The ability of antisera to guinea-pig C3 to inhibit the Arthus and local Shwartzman reactions was studied. They were found to reduce the non-haemorrhagic component of the active and reversed passive Arthus reactions and to delay the appearance of the haemorrhage in the active Arthus reaction. Cobra venom factor, howeve... | ['Animals', 'Antibodies', 'Arthus Reaction', 'Blood Platelets', 'Complement C3', 'Complement System Proteins', 'Cross Reactions', 'Endotoxins', 'Escherichia coli', 'Guinea Pigs', 'Hemorrhage', 'Immune Sera', 'Inflammation', 'Lipopolysaccharides', 'Male', 'Ovalbumin', 'Shwartzman Phenomenon', 'Skin', 'Snake Venoms', 'Ve... | 125,318 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C20.543.520.100'], ['A11.118.188', 'A15.145.229.188'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274'], ['G12.122.281'], ['D23.946.123.329'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.10... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new type of human interferon produced by peripheral blood mononuclear cells treated with inhibitors of transcription. | Peripheral blood mononuclear cells from human normal donors treated with inhibitors of transcription produce a protein with the properties of interferon (IFN) [activity against a broad range of viruses, species specificity, lack of blockade of virus attachment, capability to induce in cells durable antiviral state, est... | ["2',5'-Oligoadenylate Synthetase", 'Chromatography, Gel', 'Dactinomycin', 'Dichlororibofuranosylbenzimidazole', 'Humans', 'Interferon-gamma', 'Interferons', 'Molecular Weight', 'Monocytes', 'Neutralization Tests', 'Protein Biosynthesis', 'Transcription, Genetic'] | 2,422,300 | [['D08.811.913.696.445.625'], ['E05.196.181.400.250'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['D13.570.800.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.89... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Myocardial revascularization of the anterior descending coronary artery with left internal mammary artery by means of extracorporeal circulation: 10 years follow-up]. | BACKGROUND: The use of left internal mammary artery (LIMA) as a graft to anterior descending artery (LAD) has been associated with better long term results in coronary surgery.AIM: To assess and report the long-term results of LIMA to LAD bypass grafting for isolated LDA lesions.PATIENTS AND METHODS: Retrospective anal... | ['Actuarial Analysis', 'Adult', 'Aged', 'Angina, Unstable', 'Coronary Disease', 'Disease-Free Survival', 'Extracorporeal Circulation', 'Female', 'Follow-Up Studies', 'Humans', 'Internal Mammary-Coronary Artery Anastomosis', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Revascularization', 'Retrospective S... | 16,163,425 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Decisional algorithm in extended neoplasms of the hypopharynx and the cervical esophagus]. | Hypopharynx reconstruction must deal with restoration of not a simple tubed conduit but a complex arrangement of constrictive and propulsive forces with fine sensory circuits. The chosen surgical approach should guarantee both complete removal of tumor and re-establishement of the two primary functions of the district:... | ['Adult', 'Aged', 'Algorithms', 'Esophageal Neoplasms', 'Female', 'Humans', 'Hypopharyngeal Neoplasms', 'Male', 'Middle Aged', 'Neck', 'Reconstructive Surgical Procedures', 'Retrospective Studies'] | 16,437,981 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.485'], ['M01.060.116.630... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Histamine synthesis is required for granule maturation in murine mast cells. | Mast cells are the major sources of histamine, which is released in response to immunological stimulations. The synthesis of histamine is catalyzed by histidine decarboxylase (HDC). Previous studies have shown that Hdc(-/-) mast cells exhibit aberrant granule morphology with severely decreased granule content. Here, we... | ['Animals', 'Cell Degranulation', 'Cells, Cultured', 'Chymases', 'Coculture Techniques', 'Cytoplasmic Granules', 'Female', 'Fibroblasts', 'Histamine', 'Histidine Decarboxylase', 'Male', 'Mast Cells', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptors, G-Protein-Coupled', 'Receptors, Hista... | 24,002,822 | [['B01.050'], ['G04.468.160'], ['A11.251'], ['D08.811.277.656.300.760.103', 'D08.811.277.656.959.350.103'], ['E05.481.500.374'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A11.329.228'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['D08.811.520.224.125.30... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biofilm Formation and Motility Are Promoted by Cj0588-Directed Methylation of rRNA in Campylobacter jejuni | Numerous bacterial pathogens express an ortholog of the enzyme TlyA, which is an rRNA 2'-O-methyltransferase associated with resistance to cyclic peptide antibiotics such as capreomycin. Several other virulence traits have also been attributed to TlyA, and these appear to be unrelated to its methyltransferase activity.... | ['Amino Acid Substitution', 'Biofilms', 'Campylobacter jejuni', 'Escherichia coli', 'Gene Deletion', 'Gene Expression', 'Locomotion', 'Methylation', 'RNA, Ribosomal, 23S', 'Recombinant Proteins', 'Virulence Factors', 'tRNA Methyltransferases'] | 29,404,277 | [['E05.393.420.601.035', 'G05.558.109'], ['A20.593', 'G06.120'], ['B03.440.180.425', 'B03.660.150.235.250.500.375'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.297'], ['G07.568.500', 'G11.427.410.568'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia. | Regulatory T cells (Tregs) suppress graft-versus-host disease (GVHD) while preserving a beneficial graft-versus-leukemia (GVL) effect. Thus, their use in allogeneic stem cell transplantation (SCT) provides a promising strategy to treat GVHD. However, 3 obstacles prevent their routine use in human clinical trials: (1) l... | ['Adoptive Transfer', 'Animals', 'Azacitidine', 'CD4-Positive T-Lymphocytes', 'Cells, Cultured', 'Combined Modality Therapy', 'DNA Modification Methylases', 'Decitabine', 'Enzyme Inhibitors', 'Flow Cytometry', 'Forkhead Transcription Factors', 'Gene Expression', 'Graft vs Host Disease', 'Graft vs Leukemia Effect', 'Hum... | 20,424,188 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.251'], ['E02.186'], ['D08.811.150.240', 'D08.811.913.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fetal pulmonary maturity: relationship between optical density (650 nm) to the lecithin/sphingomyelin ratio and phosphatidylglycerol in amniotic fluid. | An optical density value greater than or equal to 0.15 at A650 n m of amniotic fluid obtained through transabdominal amniocentesis from a high risk obstetrical population, which excluded diabetes mellitus, isoimmunization, and amniotic fluid infection, correlated 98.6% with a mature lecithin to sphingomyelin ratio (L/S... | ['Amniotic Fluid', 'Female', 'Fetal Membranes, Premature Rupture', 'Fetal Organ Maturity', 'Humans', 'Infant, Newborn', 'Lung', 'Phosphatidylcholines', 'Phosphatidylglycerols', 'Pregnancy', 'Respiratory Distress Syndrome, Newborn', 'Retrospective Studies', 'Sphingomyelins'] | 6,139,307 | [['A12.098', 'A16.378.149'], ['C13.703.420.339'], ['G07.345.500.325.235.750', 'G07.345.500.325.377.249', 'G08.686.784.170.157.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A04.411'], ['D10.570.755.375.760.400.800'], ['D10.570.755.375.760.400.885'], ['G08.686.784.769'], ['C08.381.840.500... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transport and hydrolysis of enkephalins in cultured alveolar epithelial monolayers. | An in vitro cultured monolayer system of alveolar epithelial cells was used as a model to investigate transport and hydrolysis of two enkephalin peptides, Met-enkephalin (TGGPM) and [D-Ala2]Met-enkephalinamide (TAGPM), in pulmonary epithelium. Isolated alveolar type II cells formed continuous monolayers when grown on m... | ['Animals', 'Biological Transport', 'Calcimycin', 'Cells, Cultured', 'Enkephalin, Methionine', 'Epithelium', 'Hydrolysis', 'Male', 'Pulmonary Alveoli', 'Rats', 'Rats, Sprague-Dawley'] | 8,290,482 | [['B01.050'], ['G03.143'], ['D03.633.100.221.173'], ['A11.251'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['A10.272'], ['G02.380'], ['A04.411.715'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mental- and physical-health indicators and sexually explicit media use behavior by adults. | INTRODUCTION: Converging evidence from culturally diverse contexts indicates that sexually explicit media use behavior (SEMB; i.e., pornography consumption) is associated with risky sexual health perceptions and behaviors, many that involve high risks of HIV/STD transmission.AIM: Essentially unexplored, and the focus h... | ['Adolescent', 'Adult', 'Age Factors', 'Data Collection', 'Depression', 'Erotica', 'Female', 'Health Status', 'Humans', 'Male', 'Mental Health', 'Middle Aged', 'Multivariate Analysis', 'Quality of Life', 'Sex Factors', 'Sexual Behavior', 'Socioeconomic Factors', 'Washington', 'Young Adult'] | 20,946,159 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.145.126.350'], ['K01.517.414', 'L01.178.682.441'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Can rare positive interactions become common when large carnivores consume livestock? | Livestock populations in protected areas are viewed negatively because of their interaction with native ungulates through direct competition for food resources. However, livestock and native prey can also interact indirectly through their shared predator. Indirect interactions between two prey species occur when one pr... | ['Animals', 'Buffaloes', 'Cattle', 'Conservation of Natural Resources', 'Deer', 'Ecosystem', 'India', 'Lions', 'Models, Biological', 'Models, Statistical', 'Population Density', 'Predatory Behavior'] | 22,624,309 | [['B01.050'], ['B01.050.150.900.649.313.500.380.135'], ['B01.050.150.900.649.313.500.380.271'], ['J01.256', 'N06.230.080'], ['B01.050.150.900.649.313.500.380.373'], ['G16.500.275.157', 'N06.230.124'], ['Z01.252.245.393'], ['B01.050.150.900.649.313.750.377.750.600.500'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Large-pore monodispersed mesoporous silica spheres: synthesis and application in HPLC. | Monodispersed mesoporous silica spheres (MMSS) with periodical large-pore size (up to 200 A) and uniform particle size (1-1.7 mum) have successfully been synthesized by utilizing a new kind of surfactant, and they also demonstrated great potential application in HPLC. | ['Chromatography, High Pressure Liquid', 'Microscopy, Electron, Scanning', 'Particle Size', 'Porosity', 'Silicon Dioxide', 'Surface-Active Agents', 'Temperature'] | 19,225,644 | [['E05.196.181.400.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G02.712'], ['G01.374.710'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['D27.720.877'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Increasing the predictive value positive of the precipitin test for the diagnosis of deep-seated candidiasis. | Three hundred fifty human sera were tested by double immunodiffusion, crossed-line electrophoresis, and crossed immuno-affinoelectrophoresis with a concanavalin A intermediate gel for precipitating antibodies to antigens present in cytoplasmic extracts of Candida albicans. Sera from 48 of 287 hospitalized patients at r... | ['Antigens, Fungal', 'Candidiasis', 'Concanavalin A', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Immunodiffusion', 'Immunoelectrophoresis', 'Precipitin Tests'] | 102,183 | [['D23.050.202'], ['C01.150.703.160'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['E01.370.225.812.735.645.350.350', 'E05.1... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. | The ability to detect single protein molecules in blood could accelerate the discovery and use of more sensitive diagnostic biomarkers. To detect low-abundance proteins in blood, we captured them on microscopic beads decorated with specific antibodies and then labeled the immunocomplexes (one or zero labeled target pro... | ['Blood Proteins', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Male', 'Microchemistry', 'Prostate-Specific Antigen', 'Prostatectomy'] | 20,495,550 | [['D12.776.124'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.620', 'H01.181.650'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.500', 'D23.050.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolation and identification of phospholipid molecular species in alpha wild marine shrimp Penaeus kerathurus muscle and cephalothorax. | The concentration of TL in Penaeus kerathurus muscle and cephalothorax was 1.03+/-0.04 (75.9+/-0.8% of which was PhL) and 2.36+/-0.07% (45.5+/-0.8% of which was PhL) of the wet tissue, respectively. The phosphatidylethanolamine represented 26.4+/-0.6% (85.6% diacyl- and 14.4% alkyl-acyl- or alkenyl-acyl-analogues) of m... | ['Animals', 'Biochemistry', 'Chemistry, Physical', 'Chromatography, Thin Layer', 'Fatty Acids', 'Fatty Acids, Unsaturated', 'Gas Chromatography-Mass Spectrometry', 'Lipids', 'Models, Statistical', 'Muscles', 'Penaeidae', 'Phosphatidylcholines', 'Phosphatidylethanolamines', 'Phospholipids', 'Thorax'] | 18,252,200 | [['B01.050'], ['H01.158.201', 'H01.181.122'], ['H01.181.529'], ['E05.196.181.400.537'], ['D10.251'], ['D10.251.355'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D10'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['A02.633', 'A10.690'], ['B01.050.500.131.365.190.660'], ['D10.570.... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Autocrine growth factors for human tumor clonogenic cells. | A human epithelial-derived cell line, SW-13, releases a soluble substance that functions as an autocrine growth factor. SW-13 cells, derived from a human adenocarcinoma of the adrenal cortex, form a few small colonies when suspended in soft agar at low densities. The number of colonies increased significantly when eith... | ['Adenocarcinoma', 'Adrenal Gland Neoplasms', 'Agar', 'Cell Division', 'Cell Line', 'Culture Media', 'Epithelium', 'Growth Substances', 'Humans'] | 4,067,361 | [['C04.557.470.200.025'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['D09.698.360.041'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D27.720.470.305', 'E07.206'], ['A10.272'], ['D27.505.696.377'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple tests of cost-effectiveness angles. | Cost-effectiveness angles are an attractive measure of performance when comparing effects and costs of health-care therapies because they have a clear interpretation and are well suited for statistical inference. In clinical trials, a common setup is the comparison of multiple new therapies with a single control. If co... | ['Biostatistics', 'Clinical Trials as Topic', 'Cost-Benefit Analysis', 'Health Care Costs', 'Humans', 'Linear Models', 'Models, Statistical', 'Randomized Controlled Trials as Topic'] | 22,826,103 | [['E05.318.740.237'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['N03.219.151.125'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Computational analysis of composite regulatory elements. | Combinatorial regulation is a powerful mechanism for generating specificity in gene expression, and it is thought to play a pivotal role in the formation of the complex gene regulatory networks found in higher eukaryotes. The term "Composite Element" (CE) refers to a minimal functional unit where protein-DNA and protei... | ['Binding Sites', 'Chi-Square Distribution', 'Computational Biology', 'DNA', 'Gene Expression Regulation', 'Promoter Regions, Genetic', 'Regulatory Sequences, Nucleic Acid', 'Sequence Analysis, DNA', 'Transcription Factors'] | 12,115,037 | [['G02.111.570.120'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['H01.158.273.180', 'L01.313.124'], ['D13.444.308'], ['G05.308'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.570.080.689', 'G05.360.080.689'], ['E05.3... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Inflammation and wound healing in cats with chronic gingivitis/stomatitis after extraction of all premolars and molars were not affected by feeding of two diets with different omega-6/omega-3 polyunsaturated fatty acid ratios. | Feline chronic gingivitis/stomatitis (FCGS) is a painful inflammatory disease in cats. Extraction of teeth, including all premolars and molars, has been shown to be the therapy of choice in cats not responding sufficiently to home care (e.g. tooth brushing) and/or medical treatment (corticosteroids and/or antibiotics).... | ['Animal Feed', 'Animals', 'Cat Diseases', 'Cats', 'Chronic Disease', 'Diet', 'Fatty Acids, Omega-3', 'Fatty Acids, Omega-6', 'Female', 'Gingivitis', 'Inflammation', 'Male', 'Stomatitis', 'Tooth Extraction', 'Wound Healing'] | 21,762,427 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C23.550.291.500'], ['G07.203.650.240'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['D10.251.355.343'], ['C01.408', 'C07.465.714.258.480'], ['C23.550.470'], ['C07.465.864'], ['E0... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Augmentation therapy with cilostazol for the intractable geriatric major depressive disorder patients with deep white matter hyperintensities on T2-weighted brain MRI]. | Several studies report that vascular lesions contribute to depression in late life, but whether vascular lesions contribute to depression or indeed result from depression is debatable. To address this question, we segregated mood disorder patients into late- and early-onset mood disorder groups (LOM and EOM, respective... | ['Aged', 'Brain', 'Cerebrovascular Disorders', 'Cilostazol', 'Depressive Disorder, Major', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Phosphodiesterase 3 Inhibitors', 'Tetrazoles'] | 22,568,064 | [['M01.060.116.100'], ['A08.186.211'], ['C10.228.140.300', 'C14.907.253'], ['D03.383.129.617.293', 'D03.633.100.810.069'], ['F03.600.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['D27.505.519.389.735.249'], ['D03.383.129.617']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The usefulness of dynamically categorizing search results. | OBJECTIVE: The authors' goal was to determine whether dynamic categorization, a new technique for organizing search results, is more useful than the two existing organizational techniques: relevance ranking and clustering. They define a useful tool as one that helps users learn about the kinds of information that perta... | ['Algorithms', 'Analysis of Variance', 'Breast Neoplasms', 'Consumer Behavior', 'Databases, Bibliographic', 'Female', 'Humans', 'Information Management', 'Information Storage and Retrieval', 'Surveys and Questionnaires'] | 11,062,234 | [['G17.035', 'L01.224.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C04.588.180', 'C17.800.090.500'], ['F01.145.236'], ['L01.313.500.750.300.188.300', 'L01.470.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399'], ['L01.313.500.750.280', 'L01.470'], ['E05.318.308.980', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of hypoxia on the catecholamine release, Ca2+ uptake, and cytosolic free Ca2+ concentration in cultured bovine adrenal chromaffin cells. | The purpose of the present study is to clarify the effects of hypoxia on catecholamine release and its mechanism of action. For this purpose, using cultured bovine adrenal chromaffin cells, we examined the effects of hypoxia on high (55 mM) K(+)-induced increases in catecholamine release, in cytosolic free Ca2+ concent... | ['Adenosine Triphosphate', 'Adrenal Medulla', 'Anaerobiosis', 'Animals', 'Biological Transport, Active', 'Calcium', 'Calcium Radioisotopes', 'Catecholamines', 'Cattle', 'Cells, Cultured', 'Cytosol', 'Digitonin', 'Hypoxia', 'Kinetics', 'Potassium Chloride'] | 2,398,351 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A06.300.071.265'], ['G02.111.062', 'G03.078'], ['B01.050'], ['G03.143.310'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.552.100.500.325', 'D01.496.098.325', 'D01.496.749.113', 'D01.552.539.288.500.325'], ['D02.092.31... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Familial aggregation and heritability of pyloric stenosis. | CONTEXT: Pyloric stenosis is the most common condition requiring surgery in the first months of life. Case reports have suggested familial aggregation, but to what extent this is caused by common environment or inheritance is unknown.OBJECTIVES: To investigate familial aggregation of pyloric stenosis from monozygotic t... | ['Cohort Studies', 'Databases, Factual', 'Denmark', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Inheritance Patterns', 'Male', 'Pyloric Stenosis', 'Twins, Monozygotic'] | 20,551,410 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Ecological effects of home-based, school-based, and community-based training of parents of children with learning and behavior problems. | A federally funded three year project to train parents of children with learning and behavior problems is discussed in terms of its ecological impact on parents, their children, their children's teachers, and on the community at large. The design of the project including the home intervention component, the school-base... | ['Child', 'Child Behavior Disorders', 'Education, Special', 'Follow-Up Studies', 'Humans', 'Learning Disabilities', 'Parents', 'Social Environment'] | 3,440,658 | [['M01.060.406'], ['F03.625.141'], ['I02.233.213'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Antibodies to CagA protein are associated with gastric atrophy in Helicobacter pylori infection. | Strains of Helicobacter pylori which express the product of the cytotoxin associated gene A(CagA) are associated with duodenal ulceration. Also there is evidence that the presence of serum IgG antibodies to CagA is associated with an increased risk of gastric cancer of the intestinal type. Gastric atrophy is a precurso... | ['Adult', 'Aged', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Bacterial Proteins', 'Case-Control Studies', 'Duodenal Ulcer', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Gastritis, Atrophic', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Immunoglobulin G', 'Male', 'Middle Aged', 'Prevalence', 'Pr... | 8,853,252 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D12.776.097'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['E05.478.566.350.170... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A porphyrin-DNA exciplex: resonance Raman spectra of electronically excited Cu(TMpy-P4) bound to poly(dA-dT).poly(dA-dT). | The resonance Raman spectra of water-soluble porphyrins, Cu(TMpy-P4) and Ni(TMpy-P4), and their mixtures with DNA, Poly(dG-dC).Poly(dG-dC), and Poly(dA-dT).Poly(dA-dT) were measured using 426 nm pulsed laser excitation (and 556 nm for some applications). At high laser power, the solution of Cu(TMpy-P4) mixed with DNA o... | ['Copper', 'DNA', 'Mesoporphyrins', 'Nickel', 'Poly dA-dT', 'Polydeoxyribonucleotides', 'Porphyrins', 'Spectrum Analysis, Raman', 'Thermodynamics'] | 2,367,549 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D13.444.308'], ['D03.383.129.578.840.500.620', 'D03.633.400.909.500.620', 'D04.345.783.500.620', 'D23.767.727.620'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['D13.695.578.500.300'], ['D13.695.578.500'], ['D03.383.129.578.840.500', 'D03.633... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO. | Deleted in colorectal cancer (DCC), a large transmembrane receptor of netrin-1, is critical for mediating netrin-1's cardioprotective function. In the present study we investigated novel mechanisms underlying netrin-1-induced, rapid, and feed-forward up-regulation of DCC, which is believed to sustain nitric oxide (NO) ... | ['Animals', 'DCC Receptor', 'HEK293 Cells', 'Heart', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Myocardial Infarction', 'Nerve Growth Factors', 'Netrin-1', 'Nitric Oxide', 'Nuclear Proteins', 'Receptors, Cell Surface', 'Tumor Suppressor Proteins', 'Ubiquitin-Protein Ligases'] | 25,561,546 | [['B01.050'], ['D12.644.360.075.413', 'D12.776.476.075.413', 'D12.776.543.750.003.500', 'D12.776.624.776.021'], ['A11.251.210.172.750', 'A11.436.334'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Application of the Sequential Organ Failure Assessment Score to predict outcome in critically ill dogs: preliminary results. | In human medicine the Sequential Organ Failure Assessment (SOFA) score is one of the most commonly organ dysfunction scoring systems used to assess critically ill patients and to predict the outcome in Intensive Care Units (ICUs). It is composed of scores from six organ systems (respiratory, cardiovascular, hepatic, co... | ['Animals', 'Dog Diseases', 'Dogs', 'Female', 'Male', 'Organ Dysfunction Scores', 'Prognosis', 'Sepsis', 'Systemic Inflammatory Response Syndrome'] | 22,851,431 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.308.980.438.475.456.500.625', 'N05.715.360.300.800.438.375.364.500.625', 'N06.850.520.308.980.438.475.364.500.625'], ['E01.789'], ['C01.757', 'C23.550.470.790.500'], ['C23.550.470.790', 'C23.550.835.900']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tetracycline resistance of Corynebacterium diphtheriae isolated from diphtheria patients in Jakarta, Indonesia. | Of 133 Corynebacterium diphtheriae isolates from diphtheria patients in Jakarta, Indonesia, 86% were resistant to greater than or equal to 32 micrograms of tetracycline per ml. All isolates were sensitive to ampicillin, cephalothin, chloramphenicol, clindamycin, penicillin, erythromycin, and kanamycin. The general resi... | ['Corynebacterium diphtheriae', 'Diphtheria', 'Drug Resistance, Microbial', 'Humans', 'Indonesia', 'Tetracycline'] | 6,808,914 | [['B03.510.024.250.150', 'B03.510.460.400.400.200.150'], ['C01.150.252.410.040.246.388'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['D02.455.426.559.847.562.900.875', 'D04.615.562.900.875']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Antagonism between apoptotic (Bax/Bcl-2) and anti-apoptotic (IAP) signals in human osteoblastic cells under vector-averaged gravity condition. | A functional disorder associated with weightlessness is well documented in osteoblasts. The apototic features of this disorder are poorly understood. Harmful stress induces apoptosis in cells via mitochondria and/or Fas. The Bax triggers cytochrome c release from mitochondria, which can be blocked by the Bcl-2. Release... | ['Adult', 'Apoptosis', 'Cell Division', 'Cell Survival', 'Cells, Cultured', 'Gene Expression Regulation', 'Gravitation', 'Humans', 'Kinetics', 'Male', 'Osteoblasts', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-bcl-2', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'bcl-2-Associated X Pro... | 15,033,709 | [['M01.060.116'], ['G04.146.954.035'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['A11.251'], ['G05.308'], ['G01.060.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A11.329.629'], ['D12.776.624.664.700'], ['D12.644.360.075.718', 'D12... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Uncharged tRNA error damping model. | Uncharged tRNA is known to bind to the ribosome in a codon-specific fashion. In this way, cognate uncharged tRNA competes with non-cognate aminoacyl-tRNA. If uncharged tRNA can be aminoacylated while on the ribosome, this will damp errors due to aminoacyl-tRNA imbalance. Kinetic analysis shows that this scheme reduces ... | ['Binding, Competitive', 'Codon', 'Kinetics', 'Models, Biological', 'Mutation', 'Peptidyl Transferases', 'Protein Biosynthesis', 'RNA, Messenger', 'RNA, Transfer', 'RNA, Transfer, Amino Acyl', 'Ribosomes'] | 3,639,013 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['G01.374.661', 'G02.111.490'], ['E05.599.395'], ['G05.365.590'], ['D08.811.913.050.200.700'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D13.444.735.544'], ['D13.444.735.757'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interspecies pheromone signaling promotes biofilm formation and same-sex mating in Candida albicans. | The opportunistic pathogen Candida albicans undergoes a parasexual mating cycle in which cells must switch from the conventional "white" form to the alternative "opaque" form to become mating competent. Pheromones secreted by opaque cells induce the formation of polarized mating projections and result in cell-cell conj... | ['Biofilms', 'Candida albicans', 'Fungal Proteins', 'Mating Factor', 'Peptides', 'Reproduction', 'Signal Transduction'] | 21,262,815 | [['A20.593', 'G06.120'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D12.776.354'], ['D12.644.368', 'D23.641.200'], ['D12.644'], ['G08.686.784'], ['G02.111.820', 'G04.835']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Failure of porcine aortic and bovine pericardial prosthetic valves: an experimental investigation in young sheep. | Seventeen porcine aortic and 10 bovine pericardial bioprosthetic valves were implanted in the tricuspid position in 27 young sheep. Clinical, hemodynamic and morphologic evaluations were performed after a mean of 4.7 +/- 0.3 months (range 3-7 months) after implantation. Eight sheep developed ascites (five with porcine ... | ['Animals', 'Ascites', 'Bioprosthesis', 'Calcinosis', 'Heart Valve Diseases', 'Heart Valve Prosthesis', 'Hemodynamics', 'Pericardium', 'Postoperative Complications', 'Sheep', 'Tricuspid Valve', 'Tricuspid Valve Insufficiency', 'Tricuspid Valve Stenosis'] | 7,083,535 | [['B01.050'], ['C23.550.081'], ['E07.695.100'], ['C18.452.174.130'], ['C14.280.484'], ['E07.695.310'], ['G09.330.380'], ['A07.541.795', 'A10.615.789.470'], ['C23.550.767'], ['B01.050.150.900.649.313.500.380.791'], ['A07.541.510.893'], ['C14.280.484.856'], ['C14.280.484.911']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rescaled range analysis applied to the study delayed rectifier potassium channel kinetics. | The gating of ion channels has widely been modeled by assuming that the transitions between open and closed states are a memoryless process. Nevertheless, analysis of records of unitary current events suggests that the kinetic process presents long lags (antipersistent correlation). Here, using the patch-voltage clamp ... | ['Animals', 'Delayed Rectifier Potassium Channels', 'Electrochemistry', 'Female', 'Ganglia, Spinal', 'Kinetics', 'Male', 'Markov Chains', 'Membrane Potentials', 'Neurons', 'Patch-Clamp Techniques', 'Potassium Channels', 'Potassium Channels, Voltage-Gated', 'Rats', 'Rats, Sprague-Dawley'] | 14,516,913 | [['B01.050'], ['D12.776.157.530.400.600.900.124', 'D12.776.543.550.450.750.900.124', 'D12.776.543.585.400.750.900.124'], ['H01.181.529.307'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G01.374.661', 'G02.111.490'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Role of health education in school-children with particular reference to malaria. | Knowledge and effect of health education in schoolchildren of primary, secondary and higher secondary classes were evaluated. In schoolchildren exposed to different health education activities such as live demonstrations, slide shows and when both events were grouped together a high average of correct score (47.88%) in... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Health Education', 'Humans', 'India', 'Malaria', 'Male', 'Schools'] | 8,936,290 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['C01.610.752.530', 'C01.920.875'], ['I02.783', 'J03.832']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Tanzawana flavomaculata (Hymenoptera, Ichneumonidae, Ctenopelmatinae), a new genus and species of parasitoid of Fagineura crenativora (Tenthredinidae, Nematinae), a serious pest of beech tree. | We describe a new genus, and a new species, of parasitoid--Tanzawana flavomaculata Watanabe & Kasparyan (Hymenoptera: Ichneumonidae: Ctenopelmatinae)--based on material collected in Honshu, Japan. As T. flavomaculata is found on Fagineura crenativora Vikberg & Zinovjev, 2000 (Hymenoptera: Tenthredinidae), a serious pes... | ['Animal Distribution', 'Animal Structures', 'Animals', 'Body Size', 'Fagus', 'Female', 'Hymenoptera', 'Japan', 'Male', 'Organ Size', 'Plant Diseases', 'Trees'] | 26,624,663 | [['F01.145.113.069', 'G16.049'], ['A13'], ['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.650.940.800.575.912.250.859.750.300.249'], ['B01.050.500.131.617.720.500.500.875'], ['Z01.252.474.463', 'Z01.639.595'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.1... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
DNA methyltransferase 1(DNMT1) induced the expression of suppressors of cytokine signaling3 (Socs3) in a mouse model of asthma. | DNMT1 is the most important methyltransferase enzyme, involved in the regulation of gene expression and appropriate histone modification. It interact with proliferating cell nuclear antigen (PCNA), SNF2 family member ATP-dependent chromatin remodeling enzyme, cyclin dependent kinases inhibitor, E2F1 transcription facto... | ['Acetylation', 'Animals', 'Asthma', 'CpG Islands', 'DNA (Cytosine-5-)-Methyltransferase 1', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Methylation', 'Disease Models, Animal', 'Epigenesis, Genetic', 'Female', 'Gene Expression Profiling', 'Histone Acetyltransferases', 'Histone Deacetylases', 'Histones', 'Mice', 'Mice,... | 24,599,782 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D08.811.913.555.500.350.100.500.500', 'D12.776.157.687.313', 'D12.776.660.720.313'], ['D08.811.913.5... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study. | OBJECTIVES: To understand the impact of mild-moderate and severe acute kidney injury in patients with acute respiratory distress syndrome.DESIGN: Secondary analysis of the "Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure", an international prospective cohort study of patien... | ['Acute Kidney Injury', 'Adult', 'Aged', 'Aged, 80 and over', 'Carbon Dioxide', 'Comorbidity', 'Creatinine', 'Female', 'Glomerular Filtration Rate', 'Hospital Mortality', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Odds Ratio', 'Prospective Studies', 'Respiration, Artificial', 'Respiratory Distress Syndro... | 31,162,201 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['N05.715.350.225', 'N06.850.490.687'], ['D03.383.129.308.207'], ['E01.370.390.400.300', 'G08.852.357'], ['E05.318.308.985.550.400', 'N01.224.935.698.400... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tendon excursion and dehiscence during early controlled mobilization after flexor tendon repair in zone II: an x-ray stereophotogrammetric analysis. | The effect of different methods on early controlled mobilization of the flexor profundus tendon regarding tendon excursion and dehiscence was examined during treatment of 20 tendons in 18 patients. An application of radiographic stereophotogrammetric analysis on movements of tendon tissue was developed and the tendons ... | ['Adolescent', 'Adult', 'Animals', 'Early Ambulation', 'Exercise Therapy', 'Finger Injuries', 'Humans', 'Middle Aged', 'Photogrammetry', 'Prostheses and Implants', 'Rabbits', 'Radiography', 'Surgical Wound Dehiscence', 'Tantalum', 'Tendon Injuries', 'Tendons'] | 1,880,365 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['E02.760.169.063.500.335', 'E02.831.335'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['C26.448.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.600.630'], ['E07.695'], ['B01.050.150.900.649.313.968.700'], ['E... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Emerging rickettsioses of the Thai-Myanmar border. | To investigate the presence of rickettsioses in rural residents of the central Thai-Myanmar border, we tested the blood of 46 patients with fever. Four patients had murine typhus, three patients had scrub typhus, and eight patients had spotted fever group rickettsioses, including the first case of Rickettsia felis infe... | ['Adult', 'Aged', 'Anti-Bacterial Agents', 'Communicable Diseases, Emerging', 'Doxycycline', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myanmar', 'Rickettsia', 'Rickettsiaceae Infections', 'Thailand'] | 12,737,744 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['C01.221.500', 'C23.550.291.531.750'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.252.145.570'], ['B03.660.050.783.875.650.650'], ['C01.150.252.400.789', 'C01.920... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Improved Prediction of Surgical Resectability in Patients with Glioblastoma using an Artificial Neural Network. | In managing a patient with glioblastoma (GBM), a surgeon must carefully consider whether sufficient tumour can be removed so that the patient can enjoy the benefits of decompression and cytoreduction, without impacting on the patient's neurological status. In a previous study we identified the five most important anato... | ['Aged', 'Brain Neoplasms', 'Clinical Decision-Making', 'Glioblastoma', 'Humans', 'Machine Learning', 'Magnetic Resonance Imaging', 'Middle Aged', 'Neural Networks, Computer', 'Predictive Value of Tests', 'Prognosis'] | 32,198,487 | [['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.055'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E01.370.350.825.500'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pitfall to modified in vivo method of technetium-99m red blood cell labeling. Iodinated contrast media. | Suboptimal labeling of red blood cells with Tc-99m, using the modified in vivo technique, was observed in three patients in whom labeling was attempted following IV administration of iodinated contrast media in the previous 24 hours. The mechanism is not understood, but it may represent a change in either stannous ion ... | ['Child, Preschool', 'Diatrizoate', 'Diatrizoate Meglumine', 'Drug Combinations', 'Drug Interactions', 'Erythrocytes', 'Female', 'Heart', 'Humans', 'Isotope Labeling', 'Male', 'Middle Aged', 'Radionuclide Imaging', 'Technetium', 'Time Factors'] | 6,653,013 | [['M01.060.406.448'], ['D02.241.223.100.400.880.270', 'D02.455.426.559.389.127.375.880.270'], ['D02.033.800.813.550.500', 'D02.241.223.100.400.880.270.500', 'D02.455.426.559.389.127.375.880.270.500', 'D09.067.342.600.500', 'D09.853.813.550.500'], ['D26.310'], ['G07.690.773.968'], ['A11.118.290', 'A11.443.240', 'A15.145... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Construction and biomechanical properties of polyaxial self-locking anatomical plate based on the geometry of distal tibia. | In order to provide scientific and empirical evidence for the clinical application of the polyaxial self-locking anatomical plate, 80 human tibias from healthy adults were scanned by spiral CT and their three-dimensional images were reconstructed using the surface shaded display (SSD) method. Firstly, based on the geom... | ['Adult', 'Biomechanical Phenomena', 'Female', 'Fractures, Bone', 'Humans', 'Male', 'Middle Aged', 'Prostheses and Implants', 'Tibia', 'Tomography, X-Ray Computed'] | 25,025,051 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.695'], ['A02.835.232.043.650.883'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complications of arterial puncture in anticoagulated patients. | Thirteen patients who were receiving heparin in therapeutic doses had complications after femoral or brachial arterial puncture as follows: hematomas resulting in skin slough or infection in two, neuropathies of the median nerve in two and of the femoral nerve in two, and ischemia of the forearm muscles in seven. Since... | ['Adult', 'Blood Gas Analysis', 'Brachial Artery', 'Female', 'Femoral Artery', 'Hematoma', 'Heparin', 'Humans', 'Ischemia', 'Muscles', 'Peripheral Nervous System Diseases', 'Pulmonary Embolism', 'Punctures'] | 176,165 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['A07.015.114.139'], ['A07.015.114.351'], ['C23.550.414.838'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513'], ['A02.633', 'A10.690'], ['C10.668.829'], ['C08.381.746', 'C14.907.355.350.700... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cadaveric intervertebral disc temperature mapping during disc biacuplasty. | BACKGROUND: Disc Biacuplasty is a procedure for treating discogenic pain through neuron ablation by heating intervertebral disc tissue using cooled, bipolar radiofrequency (RF) technology. This study demonstrates temperature profiles created by disc biacuplasty in human cadavers.OBJECTIVE: To assess temperature profile... | ['Body Temperature', 'Cadaver', 'Denervation', 'Electrodes, Implanted', 'Hot Temperature', 'Humans', 'Intervertebral Disc', 'Intervertebral Disc Displacement', 'Time Factors'] | 18,850,031 | [['E01.370.600.875.374', 'G07.110'], ['C23.550.260.224'], ['E04.525.210'], ['E07.305.250.319', 'E07.695.202'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.165.308.410', 'A0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Binding of ferric enterobactin by the Escherichia coli periplasmic protein FepB. | The periplasmic protein FepB of Escherichia coli is a component of the ferric enterobactin transport system. We overexpressed and purified the binding protein 23-fold from periplasmic extracts by ammonium sulfate precipitation and chromatographic methods, with a yield of 20%, to a final specific activity of 15,500 pmol... | ['Animals', 'Carrier Proteins', 'Chromatography, Affinity', 'Enterobactin', 'Escherichia coli', 'Escherichia coli Proteins', 'Ferric Compounds', 'Gene Expression', 'Iron Radioisotopes', 'Membrane Transport Proteins', 'Mice', 'Periplasm', 'Periplasmic Proteins', 'Protein Binding', 'Rabbits', 'Siderophores'] | 10,986,237 | [['B01.050'], ['D12.776.157'], ['E05.196.181.400.170'], ['D04.345.566.352', 'D12.125.154.800.937', 'D12.644.641.352'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D01.490.100'], ['G05.297'], ['D01.268.556.412.500.498', 'D01.268.956.287.500.498', 'D01.496.473.498', 'D01.496.749.514', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of Ba813 | Introduction. Bacillus cereus harbouring Ba813, a specific chromosomal marker of Bacillus anthtacis, is found in patients with severe manifestations and causes nosocomial outbreaks.Aim. We assessed the genetic characteristics and virulence of Ba813(+) B. cereus in a hospital setting.Methodology. Three neutropenic patie... | ['Anthrax', 'Bacillus anthracis', 'Bacillus cereus', 'Bacteremia', 'Bacterial Proteins', 'Cross Infection', 'DNA, Bacterial', 'Disease Outbreaks', 'Hematologic Neoplasms', 'Hospitals, Teaching', 'Humans', 'Iatrogenic Disease', 'Japan', 'Phylogeny', 'Polymerase Chain Reaction', 'Virulence'] | 32,530,394 | [['C01.150.252.410.090.072'], ['B03.300.390.400.158.218.151', 'B03.353.500.100.218.151', 'B03.510.100.100.218.151', 'B03.510.415.400.158.218.151', 'B03.510.460.410.158.218.151'], ['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Prevalence of viral hepatitis markers in the population of Portugal. | The prevalence of viral hepatitis markers in apparently healthy individuals of both sexes, born and living in both urban and rural areas of all the Portuguese provinces, was studied by radioimmunoassay.The anti-HAV prevalence was determined in 1770 individuals, 1-84 years old, divided into 8 age groups. The HBsAg preva... | ['Adolescent', 'Adult', 'Aged', 'Carrier State', 'Child', 'Child, Preschool', 'Female', 'Hepatitis A', 'Hepatitis Antibodies', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Surface Antigens', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Portugal'] | 6,334,572 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N06.850.520.169'], ['M01.060.406'], ['M01.060.406.448'], ['C01.925.440.420', 'C01.925.782.687.359.500', 'C06.552.380.705.422'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.114.254.450', 'D12.776.377.715.548.114.254.450'], ['C01.221.250.500', 'C01.92... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reconstructive limb-salvage surgery after lower extremity soft tissue sarcoma resection: A 20-year experience. | BACKGROUND: Reconstructive surgery is often required following lower extremity soft tissue sarcoma resection. The relationship between the method of plastic surgery reconstruction and postoperative wound healing or functional oncologic outcomes in this patient population is poorly understood.METHODS: We performed a ret... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amputation', 'Chemotherapy, Adjuvant', 'Female', 'Graft Survival', 'Humans', 'Limb Salvage', 'Male', 'Maryland', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Postoperative Complications', 'Radiotherapy, Adjuvant', 'Retrospective Studies', 'Sarcoma', 'Skin ... | 30,644,559 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.080'], ['E02.186.170', 'E02.319.170'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.100.814.603', 'E04.555.400', 'E04.680.350'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['M01.060.116.630'], ['C04.697... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Atypical glandular cells in cervical smears: histological correlation and a suggested plan of management based on age of the patient in a low-resource setting. | OBJECTIVES: To perform an audit of all smears reported as atypical glandular cells (AGC) using the Bethesda system (TBS) 2001.METHODS: A total of 18 376 cervical smears were screened from January 2005 to June 2007, of which 65 cases were reported as AGC. Follow-up histology was available in 31 cases (47.7%), in whom a ... | ['Adult', 'Age Factors', 'Aged', 'Biopsy', 'Carcinoma, Squamous Cell', 'Cervix Uteri', 'Female', 'Health Care Costs', 'Humans', 'Middle Aged', 'Neoplasms, Glandular and Epithelial', 'Papanicolaou Test', 'Uterine Cervical Neoplasms', 'Vaginal Smears', 'Young Adult'] | 19,207,306 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A05.360.319.679.256'], ['N03.219.151.400', 'N05.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Application of the Clinical Practice Guideline for Congenital Muscular Torticollis: A Case Report. | PURPOSE: This case report illustrates application of the Clinical Practice Guideline for Congenital Muscular Torticollis in a pediatric outpatient facility.DESCRIPTIONS: The infant was a 2-month-old baby presenting with congenital muscular torticollis. Application of each of the 16 action statements outlined in the Cli... | ['Humans', 'Infant', 'Male', 'Neck Muscles', 'Practice Guidelines as Topic', 'Range of Motion, Articular', 'Torticollis'] | 30,557,293 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A02.633.567.650'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E01.370.600.700', 'G11.427.760'], ['C23.888.592.350.300.800']] | ['Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bus accident analysis of routes with/without bus priority. | This paper summarises findings on road safety performance and bus-involved accidents in Melbourne along roads where bus priority measures had been applied. Results from an empirical analysis of the accident types revealed significant reduction in the proportion of accidents involving buses hitting stationary objects an... | ['Accidents, Traffic', 'Binomial Distribution', 'Humans', 'Law Enforcement', 'Motor Vehicles', 'Neural Networks, Computer', 'Regression Analysis', 'Safety', 'Victoria'] | 24,406,378 | [['N06.850.135.392'], ['E05.318.740.994.250', 'G17.820.250', 'N05.715.360.750.750.150', 'N06.850.520.830.994.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.594'], ['J01.937.500'], ['G17.485', 'L01.224.050.375.605'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['N06.850.135.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Joint-action ecotoxicity of binary mixtures of glutaraldehyde and surfactants used in hospitals: use of the Toxicity Index model and isoblogram representation. | Glutaraldehyde and surfactants are widely used in hospitals and these substances have been detected in urban sewer networks and in surface water. The ecotoxicity of hospital wastewater has been reported in the literature, which identifies detergents and disinfectants as the main causes of toxicity. The aim of this stud... | ['Animals', 'Biological Assay', 'Daphnia', 'Disinfectants', 'Environmental Monitoring', 'Glutaral', 'Hospitals', 'Models, Biological', 'Risk Assessment', 'Surface-Active Agents', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 17,945,345 | [['B01.050'], ['E05.091'], ['B01.050.500.131.365.150.200'], ['D27.505.954.122.425', 'D27.720.274'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.047.532'], ['N02.278.421'], ['E05.599.395'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Timing in the absence of clocks: encoding time in neural network states. | Decisions based on the timing of sensory events are fundamental to sensory processing. However, the mechanisms by which the brain measures time over ranges of milliseconds to seconds remain unclear. The dominant model of temporal processing proposes that an oscillator emits events that are integrated to provide a linea... | ['Adolescent', 'Adult', 'Biological Clocks', 'Brain', 'Choice Behavior', 'Discrimination, Psychological', 'Humans', 'Models, Neurological', 'Neural Networks, Computer', 'Principal Component Analysis', 'Psychophysics', 'Time Perception'] | 17,270,738 | [['M01.060.057'], ['M01.060.116'], ['G07.180.562.094'], ['A08.186.211'], ['F02.463.785.373.346'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['G17.485', 'L01.224.050.375.605'], ['E05.318.740.562'], ['E01.370.685', 'F04.096.753'], ['F02.463.593.857']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Feeding state influences the content of FMRFamide- and tachykinin-related peptides in endocrine-like cells of the midgut of Locusta migratoria. | The midgut of 5th instar male African migratory locust, Locusta migratoria, was found to contain endocrine-like cells that stained positively for FMRFamide-like immunoreactivity. These cells have cell bodies which are tear-drop in shape with processes extending from the cell body. FMRFamide-like immunoreactivity has be... | ['Animals', 'Eating', 'Endocrine System', 'FMRFamide', 'Grasshoppers', 'Male', 'Tachykinins'] | 11,179,816 | [['B01.050'], ['G07.203.650.283', 'G10.261.330'], ['A06'], ['D12.644.400.235', 'D12.776.631.650.235'], ['B01.050.500.131.617.678.369'], ['D12.644.276.812.900', 'D12.644.400.800', 'D12.644.456.800', 'D12.776.467.812.900', 'D12.776.631.650.800', 'D23.469.050.375.850', 'D23.529.812.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychosocial functioning of transsexuals in Belgium. | Male-to-female (M-F) transsexuals differ consistently from female-to-male (F-M) transsexuals in their sociodemographic characteristics, cross-gender and sexual history and the degree to which personality disorder is concomitant to their transsexuality. As a group, female-to-male transsexuals are more homogeneous. Both ... | ['Adult', 'Belgium', 'Female', 'Gender Identity', 'Homosexuality', 'Humans', 'Male', 'Mental Disorders', 'Netherlands', 'Personality Disorders', 'Personality Inventory', 'Psychiatric Status Rating Scales', 'Social Adjustment', 'Socialization', 'Transsexualism'] | 7,625,192 | [['M01.060.116'], ['Z01.542.115'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['F01.145.802.975.500', 'G08.686.867.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['Z01.542.651'], ['F03.675'], ['F04.711.647.513'], ['F04.711.513.653'], ['F01.145.813.621'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Neuroepithelial origin of the insular and endopiriform parts of the claustrum. | The lateral and ventral pallia have been proposed as the source of neurons for the insular and endopiriform claustra, respectively. However, this correlation is controversial. Here, we analysed this relationship by labelling radial glia in coronal slices of the telencephalon of paraformaldehyde-fixed rabbit embryos (E1... | ['Animals', 'Animals, Newborn', 'Basal Ganglia', 'Cell Movement', 'Embryo, Mammalian', 'Neuroglia', 'Neurons', 'Rabbits', 'Telencephalon', 'Vimentin'] | 11,923,017 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211.200.885.287.249'], ['G04.198', 'G07.568.500.180'], ['A16.254'], ['A08.637', 'A11.650'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.968.700'], ['A08.186.211.200.885'], ['D05.750.078.593.900', 'D12.776.220.475.900']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method. | BACKGROUND: Pancreatic ductal adenocarcinoma is an aggressive tumor; treatment remains a challenge because of the lack of effective therapeutic strategies. Basic research in this field is dependent on the availability of model systems. New pancreatic cancer cell lines are therefore important for the study of its biolog... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Cadherins', 'Cell Culture Techniques', 'Cell Line, Tumor', 'Female', 'Humans', 'Keratin-18', 'Keratin-8', 'Male', 'Middle Aged', 'Mutation', 'Pancreatic Neoplasms', 'Phenotype', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins p21(ras)', 'Smad4 Protein', 'Tum... | 21,683,373 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cricopharyngeal myotomy in the treatment of dysphagia. | Deglutition is a complex neuromuscular act. Alterations in anatomy and physiology may lead to dysphagia. The role of the cricopharyngeus appears to be the keystone in the rehabilitation of many patients with dysphagia. This paper examines the physiology of swallowing as well as the patho-physiology of its abberations. ... | ['Aged', 'Deglutition Disorders', 'Dermatomyositis', 'Esophageal Achalasia', 'Hemiplegia', 'Humans', 'Laryngeal Diseases', 'Laryngeal Neoplasms', 'Male', 'Methods', 'Middle Aged', 'Muscles', 'Neck', 'Pharynx'] | 1,195,969 | [['M01.060.116.100'], ['C06.405.117.119', 'C09.775.174'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['C06.405.117.119.500.432'], ['C10.597.622.295', 'C23.888.592.636.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360', 'C09.400'], ['C04.588.443.665.481', 'C08.360.3... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Exceptional running and turning performance in a mite. | The Southern California endemic mite Paratarsotomus macropalpis was filmed in the field on a concrete substrate and in the lab to analyze stride frequency, gait and running speed under different temperature conditions and during turning. At ground temperatures ranging from 45 to 60 °C, mites ran at a mean relative spee... | ['Animals', 'Biomechanical Phenomena', 'Extremities', 'Gait', 'Mites', 'Running', 'Temperature'] | 26,787,481 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['A01.378'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.500.131.166.132.419'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Fentanyl and diazepam in endoscopy of the upper gastrointestinal tract. | To compare the effect of fentanyl, a short-acting narcotic analgesic, with that of diazepam as intravenous premedication for endoscopy of the upper gastrointestinal tract, we allocated at random 200 consecutive outpatients requiring elective endoscopy to receive either fentanyl or diazepam; the procedure was evaluated ... | ['Aged', 'Clinical Trials as Topic', 'Diazepam', 'Digestive System', 'Endoscopy', 'Fentanyl', 'Gastroscopy', 'Humans', 'Premedication', 'Surveys and Questionnaires'] | 7,048,037 | [['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D03.633.100.079.080.070.216'], ['A03'], ['E01.370.388.250', 'E04.502.250'], ['D03.383.621.265'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['B01.050.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The meaning of nonlinear distortions in the internal ear for acoustic and ultrasonic stimuli]. | A comparative study of nonlinear distortion of microphonic potentials in the rabbit cochlear at the air and bone conduction showed equal values for the air as well as for the within the ultrasonic frequency range did not exceed the hearing spectrum values. The hearing response to ultrasonic stimuli was found not to be ... | ['Acoustic Stimulation', 'Animals', 'Bone Conduction', 'Chinchilla', 'Cochlea', 'Electrophysiology', 'Hearing', 'Rabbits', 'Ultrasonics'] | 680,260 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['F02.830.816.263.500', 'G07.888.500.500', 'G11.561.790.263.398'], ['B01.050.150.900.649.313.992.328'], ['A09.246.300.246'], ['H01.158.344.528', 'H01.158.782.236'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.968.700'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Actin--an inhibitor of eukaryotic elongation factor activities. | An inhibitor of diphtheria toxin- and endogenous transferase-dependent ADP-ribosylation of eukaryotic elongation factor 2 (eEF2) has been found in the cytoplasmic fraction from rat liver. We provide evidence that this cytoplasmic inhibitor corresponds to actin, which gives rise also to inhibition of polyphenylalanine (... | ['ADP Ribose Transferases', 'Actins', 'Adenosine Diphosphate Ribose', 'Animals', 'Cytosol', 'Deoxyribonuclease I', 'Diphtheria Toxin', 'Dose-Response Relationship, Drug', 'Hepatocytes', 'Inhibitory Concentration 50', 'Muscle, Skeletal', 'Peptide Elongation Factor 1', 'Peptide Elongation Factor 2', 'Peptides', 'Rabbits'... | 15,094,376 | [['D08.811.913.400.725.115'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.633.100.759.646.138.124.070.125', 'D09.408.620.569.070.125', 'D13.695.667.138.124.070.125', 'D13.695.827.068.124.070.125', 'D13.695.827.708.070.125'], ['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Explaining patterns of neural activity in the primary motor cortex using spinal cord and limb biomechanics models. | What determines the specific pattern of activation of primary motor cortex (M1) neurons in the context of a given motor task? We present a systems level physiological model describing the transformation from the neural activity in M1, through the muscle control signal, into joint torques and down to endpoint forces and... | ['Action Potentials', 'Animals', 'Biomechanical Phenomena', 'Extremities', 'Humans', 'Models, Biological', 'Models, Neurological', 'Motor Cortex', 'Movement', 'Muscle Contraction', 'Neurons', 'Spinal Cord'] | 17,360,816 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.599.395.642'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['G07.568', 'G11.427.410'], ['G11.427.4... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas. | Interleukin-12 (IL-12), a proinflammatory cytokine, shows anticancer properties. Systemically administered IL-12 causes dose-dependent toxicity. To achieve localized intratumoral gene expression, an adenoviral gene therapy vector with IL-12 controlled by a heat-inducible promoter (heat shock promoter 70B) was developed... | ['Adenoviridae', 'Animals', 'Cats', 'Cytomegalovirus', 'Feasibility Studies', 'Genetic Therapy', 'Green Fluorescent Proteins', 'Hyperthermia, Induced', 'Interleukin-12', 'Liver', 'Mice', 'Promoter Regions, Genetic', 'Recombinant Proteins', 'Sarcoma'] | 17,237,297 | [['B04.280.030'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B04.280.382.150.150'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E02.095.301', 'E05.393.420.301'], ['D12.776.532.265'], ['E02.565'], ['D12.644.276.374.465.512', 'D12.776.467.374.465.512', 'D23.529... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hepatic dopamine sulfotransferases in untreated rats and in rats subjected to endocrine or hypertension-related treatments. | Here we describe the dopamine sulfotransferase activity of rat liver cytosol. With cytosol, 3'-phosphoadenosine-5'-phosphosulfate and dopamine Km values were 17.2 +/- 4.1 and 22.4 +/- 3.5 microM. Females possessed 23 to 37% of dopamine sulfotransferase levels, per gm liver, in males. DEAE-Sephadex A-50 chromatography r... | ['Adrenalectomy', 'Animals', 'Arylsulfotransferase', 'Castration', 'Catecholamines', 'Chromatography', 'Cytosol', 'Female', 'Hypertension', 'Liver', 'Male', 'Rats', 'Rats, Inbred Strains', 'Sex Factors'] | 3,192,164 | [['E04.270.115'], ['B01.050'], ['D08.811.913.817.400.300'], ['E04.270.282', 'E04.950.165'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['E05.196.181'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['C14.907.489'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clear cell mesothelioma presenting as an incarcerated abdominal hernia. | A clear cell mesothelioma presenting as an incarcerated ventral abdominal hernia in a 67-year-old man who had no history of asbestos exposure is described. The cause of the cytoplasmic clearing was the presence of large amounts of glycogen. Although uncommon, this variant of mesothelioma is important to recognize becau... | ['Aged', 'Biomarkers, Tumor', 'Diagnosis, Differential', 'Glycogen', 'Hernia, Abdominal', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Mesothelioma', 'Peritoneal Neoplasms'] | 16,021,512 | [['M01.060.116.100'], ['D23.101.140'], ['E01.171'], ['D05.750.078.562.388', 'D09.698.365.388'], ['C23.300.707.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['C04.588.033.513', 'C04.588.274.780', 'C06.301... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tramadol enhances urethral continence function through µ-opioid receptors in rats. | AIMS: (±)-Tramadol hydrochloride (tramadol) is a widely used analgesic that stimulates the µ-opioid receptor and inhibits the reuptake of serotonin and noradrenalin. Although tramadol is also known to inhibit the micturition reflex in rats, its effects on urethral continence function have not been reported. We therefor... | ['Analgesics, Opioid', 'Animals', 'Female', 'Morphine', 'Naloxone', 'Narcotic Antagonists', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Opioid, mu', 'Tramadol', 'Urinary Bladder', 'Urinary Incontinence, Stress', 'Urodynamics'] | 22,674,657 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.615... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomic features of intertypic recombinant sabin poliovirus strains excreted by primary vaccinees. | The trivalent oral poliomyelitis vaccine (OPV) contains three different poliovirus serotypes. It use therefore creates particularly favorable conditions for mixed infection of gut cells, and indeed intertypic vaccine-derived recombinants (VdRec) have been frequently found in patients with vaccine-associated paralytic p... | ['Animals', 'Child', 'Chlorocebus aethiops', 'Genome, Viral', 'Humans', 'Poliovirus', 'Poliovirus Vaccine, Oral', 'Polymorphism, Restriction Fragment Length', 'RNA, Viral', 'Recombination, Genetic', 'Reverse Transcriptase Polymerase Chain Reaction', 'Vero Cells'] | 11,390,576 | [['B01.050'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.578.750.284.184.500'], ['D20.215.894.899.623.750'], ['G05.365.795.595'], ['D13.444.735.828'], ['G05.728'], ['E05.393.620.500.725'], ['A11.251.210.95... | ['Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sonodynamically-induced anticancer effects by functionalized fullerenes. | BACKGROUND: Functionalized fullerenes, such as polyhydroxy fullerenes (PHF), have attracted particular attention due to their water solubility and their potential application in tumor imaging and therapy as carbon nanomaterials. In this study, the sonodynamically-induced antitumor effect of PHF was investigated.MATERIA... | ['Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Separation', 'Free Radical Scavengers', 'Fullerenes', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred ICR', 'Nitrogen Oxides', 'Reactive Oxygen Species', 'Sarcoma 180', 'Ultrasonic Therapy'] | 23,898,072 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D27.505.519.217.500'], ['D01.268.150.250', 'J01.637.512.600.612.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.33... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Malignant cylindroma]. | A case of malignant eccrine cylindroma of the skin studied immunohistochemically is reported. | ['Carcinoma, Adenoid Cystic', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Skin Neoplasms'] | 11,076,301 | [['C04.557.470.200.025.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.727.645'], ['C04.588.805', 'C17.800.882']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computational evaluation of the reactivity and pharmaceutical potential of an organic amine: A DFT, molecular dynamics simulations and molecular docking approach. | 2-[N-(carboxymethyl)anilino] acetic acid (PIDAA) molecule has been spectroscopically characterized and computationally investigated for its fundamental reactive properties by a combination of density functional theory (DFT) calculations, molecular dynamics (MD) simulations and molecular docking procedure. A comparison ... | ['Aniline Compounds', 'Density Functional Theory', 'Electrons', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Spectroscopy, Fourier Transform Infrared', 'Spectrum Analysis, Raman', 'Thermodynamics', 'Water'] | 31,176,999 | [['D02.092.146'], ['H01.671.579.800.500'], ['G01.249.335', 'G01.358.500.750'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
A ubiquitous factor (HF-1a) and a distinct muscle factor (HF-1b/MEF-2) form an E-box-independent pathway for cardiac muscle gene expression. | Recent studies have identified a conserved 28-bp element (HF-1) within the rat cardiac MLC-2 gene which confers cardiac muscle-specific and inducible expression during myocardial cell hypertrophy. Utilizing a combination of independent experimental approaches, this study characterizes two cardiac nuclear factors which ... | ['Animals', 'Base Sequence', 'Cardiomegaly', 'Cell Differentiation', 'DNA Mutational Analysis', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Molecular Sequence Data', 'Myocardium', 'Rats', 'Recombinant Fusion Proteins', 'Regulatory Sequences, Nucleic Acid', 'Tissue Distribution'] | 1,532,229 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C14.280.195', 'C23.300.775.250'], ['G04.152'], ['E05.393.760.700.300'], ['D12.776.260'], ['G05.308'], ['L01.453.245.667'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.828.300'], ['G02... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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