Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Diphenyl diselenide in vitro and in vivo activity against the oomycete Pythium insidiosum. | This study evaluated the in vitro activity of diphenyl diselenide against 19 Pythium insidiosum isolates and the in vivo therapeutic response of rabbits with experimentally induced pythiosis. In vitro: susceptibility tests were performed using the broth macrodilution method in accordance with the CLSI document M38-A2. ... | ['Animals', 'Benzene Derivatives', 'Microbial Sensitivity Tests', 'Organoselenium Compounds', 'Pythiosis', 'Pythium', 'Rabbits'] | 22,055,205 | [['B01.050'], ['D02.455.426.559.389'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.731'], ['C01.610.701.844', 'C22.761'], ['B01.750.580.750'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distorted estimates of implicit and explicit learning in applications of the process-dissociation procedure to the SRT task. | We investigated potential biases affecting the validity of the process-dissociation (PD) procedure when applied to sequence learning. Participants were or were not exposed to a serial reaction time task (SRTT) with two types of pseudo-random materials. Afterwards, participants worked on a free or cued generation task u... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Learning', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Psychomotor Performance', 'Research Design', 'Young Adult'] | 26,277,258 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['M01.060.116.630'], ['F04.711.513'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.581.500', 'H01.770.644.728'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Outcomes of Robot-assisted Partial Nephrectomy for Clinical T2 Renal Tumors: A Multicenter Analysis (ROSULA Collaborative Group). | BACKGROUND: While partial nephrectomy (PN) represents the standard surgical management for cT1 renal masses, its role for cT2 tumors is controversial. Robot-assisted PN (RAPN) is being increasingly implemented worldwide.OBJECTIVE: To analyze perioperative, functional, and oncological outcomes of RAPN for cT2 tumors.DES... | ['Aged', 'Databases, Factual', 'Disease Progression', 'Female', 'Humans', 'Kidney Neoplasms', 'Male', 'Margins of Excision', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Neoplasm, Residual', 'Nephrectomy', 'Postoperative Complications', 'Retrospective Studies', 'Risk Factors'... | 29,784,191 | [['M01.060.116.100'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['A10.830', 'C23.149.625'], ['M01.060.116.630'], ['C04.697.650', 'C... | ['Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. | The expression of the hypoxia-responsive transcription factor hypoxia-inducible factor (HIF)-1 during acute inflammation was investigated in experimental wounds. HIF-1alpha mRNA was maximally expressed in wound cells 6 h after injury. HIF-1alpha protein was detectable in wound cells 1 and 5 days after injury. Cells fro... | ['Animals', 'Cell Line', 'Endothelial Growth Factors', 'Gene Expression Regulation', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Inflammation', 'Interleukin-1', 'Lymphokines', 'Male', 'Nitroimidazoles', 'Radiation-Sensitizing Agents', 'Rats', 'Rats, Inbred F344', 'Time Factors', 'Transcription Factors', 'Tumor Necros... | 11,698,256 | [['B01.050'], ['A11.251.210'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['G05.308'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['C23.550.470'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiation therapy of spinal metastases: results with different fractionations. | AIMS AND BACKGROUND: Local radiotherapy plays an important role in the palliative treatment of all skeletal metastases, particularly those of the spine, with the purpose to obtain pain relief and prevent pathologic fractures or vertebral collapse.METHODS: From June 1991 to October 1993, 95 patients with a total of 103 ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Dose-Response Relationship, Radiation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain', 'Radiotherapy Dosage', 'Spinal Fractures', 'Spinal Neoplasms', 'Treatment Outcome'] | 7,839,465 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.815.639'], ['C26.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid development of an axillary mass in an adult: a case of cystic hygroma. | Cystic hygroma is a congenital anomaly of lymphatic origin, which mainly develops during childhood. Its development in adulthood, however, has been proposed to be related to several predisposing factors such as trauma, infection, tumor growth or iatrogenic stimuli. The development of cystic hygroma in the extremities o... | ['Axilla', 'Female', 'Humans', 'Lymphangioma, Cystic', 'Middle Aged', 'Soft Tissue Neoplasms', 'Treatment Outcome'] | 17,713,316 | [['A01.378.800.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.375.450.450'], ['M01.060.116.630'], ['C04.588.839'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury. | OBJECTIVE: : Intracranial hypertension after severe head injury is associated with case fatality, but there is no sound evidence that monitoring of intracranial pressure (ICP) and targeted management of cerebral perfusion pressure (CPP) improve outcome, despite widespread recommendation by experts in the field. The pur... | ['Adult', 'Blood Pressure', 'Brain Injuries', 'Cerebrovascular Circulation', 'Cohort Studies', 'Critical Care', 'Female', 'Humans', 'Intracranial Pressure', 'Length of Stay', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Recovery of Function', 'Retrospective Studies', 'Treatment Outcome'] | 16,215,372 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G09.330.100.159'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.760.190', 'N02.421.585.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.561.170.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of a ratiometric fluorescent zinc ion probe in near-infrared region, based on tricarbocyanine chromophore. | Novel ratiometric fluorescent probes for Zn2+ in the near-infrared region, based on a tricarbocyanine chromophore, have been designed, synthesized, and evaluated. Upon addition of Zn2+, a 44 nm red shift of the absorption maximum was observed, which indicates that this probe could work as a ratiometric probe for Zn2+. ... | ['Alkanesulfonates', 'Carbocyanines', 'Coloring Agents', 'Fluorescent Dyes', 'Infrared Rays', 'Zinc'] | 16,704,241 | [['D02.455.326.146.100.050', 'D02.886.645.600.055.050'], ['D02.455.326.397.300'], ['D27.720.233'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.770.578.552', 'G16.500.275.063.725.525.400', 'G16.500.750.775.525.400', 'N06.230.300.100.725.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The ear lobe crease sign and coronary artery disease in aortic stenosis. | Ear lobe creases have been proposed as useful indirect markers of coronary artery disease. To test such a hypothesis, this physical sign was evaluated in 100 patients with symptomatic aortic stenosis undergoing cardiac catheterization to establish the hemodynamic severity of the obstruction and the degree of coronary a... | ['Adult', 'Aged', 'Aortic Valve Stenosis', 'Coronary Disease', 'Ear, External', 'Female', 'Humans', 'Male', 'Middle Aged', 'Regression Analysis', 'Sex Factors'] | 3,731,565 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.484.048.750', 'C14.280.955.249'], ['C14.280.647.250', 'C14.907.585.250'], ['A09.246.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['N05.715.350.675', 'N06.850.490.875']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of publication output in the field of general practice and family medicine and by general practitioners and general practice institutions. | PURPOSE: The discipline of family medicine (FM) lacks a comprehensive methodology, which can be applied as a standard for assessing overall research output in both the field of FM and by general practitioners (GPs)/general practice institutions. It was the aim of this study to develop a sensitive search strategy for as... | ['Bibliometrics', 'Biomedical Research', 'Databases, Bibliographic', 'Family Practice', 'General Practice', 'General Practitioners', 'Periodicals as Topic', 'PubMed'] | 20,554,654 | [['L01.178.682.099.325', 'L01.453.183.291'], ['H01.770.644.145'], ['L01.313.500.750.300.188.300', 'L01.470.750.500'], ['H02.403.340.500'], ['H02.403.340'], ['M01.526.485.810.485', 'N02.360.810.485'], ['L01.178.682.829.678'], ['L01.313.500.750.280.750', 'L01.313.500.750.300.188.300.650', 'L01.313.500.750.300.742.650', '... | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Hypercholesterolemic mice exhibit lymphatic vessel dysfunction and degeneration. | Lymphatic vessels are essential for lipid absorption and transport. Despite increasing numbers of observations linking lymphatic vessels and lipids, little research has been devoted to address how dysregulation of lipid balance in the blood, ie, dyslipidemia, may affect the functional biology of lymphatic vessels. Here... | ['Animals', 'Apolipoproteins E', 'Cell Count', 'Cell Movement', 'Dendritic Cells', 'Hypercholesterolemia', 'Lymphatic Vessels', 'Mice', 'Muscle, Smooth, Vascular'] | 19,679,879 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.198', 'G07.568.500.180'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C18.452.584.500.500.396'], ['A15.382.520.301'], ['B01.050.150.900... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Utility of ERBB4 and RB1 Immunohistochemistry in Distinguishing Chromophobe Renal Cell Carcinoma From Renal Oncocytoma. | Objectives. Differentiating renal oncocytoma (RO) from chromophobe renal cell carcinoma (ChRCC) can occasionally be challenging. We evaluated the expression of RB1 and ERBB4 in RO and ChRCC, and compared the immunohistochemistry (IHC) results to RB1 and ERBB4 gene abnormalities detected by fluorescence in situ hybridiz... | ['Adenoma, Oxyphilic', 'Biomarkers, Tumor', 'Carcinoma, Renal Cell', 'Diagnosis, Differential', 'Humans', 'Immunohistochemistry', 'Kidney Neoplasms', 'Receptor, ErbB-4', 'Retinoblastoma Binding Proteins', 'Ubiquitin-Protein Ligases'] | 31,640,438 | [['C04.557.470.035.140'], ['D23.101.140'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Baicalein improves glucose metabolism in insulin resistant HepG2 cells. | Insulin resistance (IR) is the primary pathogenesis of Type 2 diabetes mellitus (T2DM). Scutellaria baicalensis Georgi is a traditional Chinese herbal medicine, often used in the clinical treatment of T2DM. Baicalein which is considered to have anti-IR effects is one of its active ingredients. IR-induced HepG2 cells we... | ['Antigens, CD', 'Flavanones', 'Gene Expression Regulation, Enzymologic', 'Glucose', 'Glucose-6-Phosphatase', 'Hep G2 Cells', 'Humans', 'Insulin Receptor Substrate Proteins', 'Insulin Resistance', 'Phosphatidylinositol 3-Kinases', 'Phosphoenolpyruvate Carboxykinase (ATP)', 'Proto-Oncogene Proteins c-akt', 'Receptor, In... | 30,970,232 | [['D23.050.301.264.035', 'D23.101.100.110'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['G05.308.320'], ['D09.947.875.359.448'], ['D08.811.277.352.650.225'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.024.301', 'D12.776.157.057.045', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An oncology unit's initiation of a bereavement support program. | PURPOSE/OBJECTIVES: To describe how a multidisciplinary task force on an oncology unit developed and implemented a program offering educational and emotional support for recently bereaved families.DATA SOURCES: Published books and articles and bereavement support models.DATA SYNTHESIS: Program components included berea... | ['Bereavement', 'Family', 'Grief', 'Hospital Bed Capacity, 500 and over', 'Humans', 'Oncology Service, Hospital', 'Patient Care Team', 'Professional-Family Relations', 'Program Development', 'Social Support', 'Survivors', 'Texas'] | 7,854,930 | [['F01.470.142'], ['F01.829.263', 'I01.880.853.150'], ['F01.470.142.110'], ['N02.278.306.472.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.513', 'N04.452.442.452.422.513'], ['N04.590.715'], ['F01.829.401.550'], ['N04.452.760'], ['I01.880.853.500.600'], ['M01.860'], ['Z01.107.567.875.760.... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP. | We have raised specific antibodies against the PRP6 protein and shown that the U4, U5 and U6 snRNAs are co-precipitated with this protein. Using splicing extracts prepared from in vivo heat-inactivated cells, we have characterized the prp4-1 and prp6-1 biochemical defects. In inactivated prp4-1 cell extracts, the U6 sn... | ['Centrifugation, Density Gradient', 'Fungal Proteins', 'Glycerol', 'Mutation', 'Precipitin Tests', 'RNA Splicing', 'Ribonucleoprotein, U4-U6 Small Nuclear', 'Ribonucleoprotein, U5 Small Nuclear', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Spliceosomes'] | 8,479,905 | [['E05.181.724.336', 'E05.196.941.336'], ['D12.776.354'], ['D02.033.800.875.500', 'D09.853.875.500'], ['G05.365.590'], ['E01.370.225.812.735.645', 'E05.196.150.639.500', 'E05.200.812.735.645', 'E05.478.594.760.645', 'E05.478.605.492'], ['G02.111.760.700', 'G03.839.700', 'G05.308.700.700'], ['D12.776.157.725.500.875.615... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Protein binding glucocorticoid hormones (transcortin) during peri-and postnatal ontogenesis and pregnancy in rats]. | The constants of association and the energy of interaction between transcortin and cortisol, the binding ability and other characteristics of transcortin have been studied in the embryos, sexually immature and mature young and old females, females on the 14th and 21st days of pregnancy, immature and mature males. The c... | ['Age Factors', 'Animals', 'Body Weight', 'Corticosterone', 'Electrophoresis, Disc', 'Female', 'Fetal Blood', 'Male', 'Maternal-Fetal Exchange', 'Pregnancy', 'Progesterone', 'Rats', 'Sex Factors', 'Transcortin', 'Ultracentrifugation'] | 1,026,881 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['E05.196.401.402.236', 'E05.301.300.319.403'], ['A12.207.152.200', 'A15.145.300', 'A16.3... | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression. | Advanced human thyroid cancers are densely infiltrated with tumor-associated macrophages (TAMs) and this correlates with a poor prognosis. We used BRAF-induced papillary thyroid cancer (PTC) mouse models to examine the role of TAMs in PTC progression. Following conditional activation of BRAF(V600E) in murine thyroids t... | ['Animals', 'Anisoles', 'Carcinoma', 'Carcinoma, Papillary', 'Cell Movement', 'Chemokine CCL2', 'Disease Progression', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Macrophage Colony-Stimulating Factor', 'Macrophages', 'Mice', 'Mice, Transgenic', 'Protein Kinase Inhibitors', 'Proto-Oncogene Proteins B-raf', 'Pyr... | 23,372,702 | [['B01.050'], ['D02.355.601.200', 'D02.355.726.158', 'D02.455.426.559.389.657.654.158'], ['C04.557.470.200'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['G04.198', 'G07.568.500.180'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Sanitary chemical research on the atmosphere in wards for cardiac patients]. | Man passes a greater part of the day-and-night in closed premises. The pollutants of the inside air, in quantity and quality are more various than that of the atmospheric air, which is due to the additional sources of pollution. The investigation performed is part of a complex study and hygienic assessment of the envir... | ['Air', 'Air Pollution, Indoor', 'Bulgaria', 'Heart Diseases', 'Hospital Units', 'Humans', 'Microclimate'] | 1,796,108 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['N06.850.460.100.080'], ['Z01.542.248.180'], ['C14.280'], ['N02.278.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.275.071.450', 'N06.230.300.100.250.450']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Isolation of Mycoplasma from the placenta after cesarean section. | Placentas obtained at cesarean section were cultured for Mycoplasma and other microorganisms in 123 randomly selected patients in order to evaluate the incidence of Mycoplasma, to identify factors which may contribute to their presence, and to correlate their presence with the occurrence of postpartum infection. Twenty... | ['Cesarean Section', 'Extraembryonic Membranes', 'Female', 'Humans', 'Labor, Obstetric', 'Mycoplasma', 'Mycoplasma Infections', 'Placenta', 'Pregnancy', 'Puerperal Infection'] | 995,338 | [['E04.520.252.500'], ['A10.615.284', 'A16.254.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['B03.440.860.580.553.553'], ['C01.150.252.400.610.610'], ['A16.710'], ['G08.686.784.769'], ['C01.674.715', 'C13.703.700.715', 'C13.703.844.757']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Critical Issues on Diverticular Disease. | In this session diverse critical issues in diverticular disease were considered, including "In or outpatient management of uncomplicated diverticulitis?", "Segmental colitis associated with diverticulosis: what is it?"and "Diverticular inflammation is a risk factor for colorectal cancer?". The conclusions drawn are out... | ['Ambulatory Care', 'Colitis', 'Colorectal Neoplasms', 'Delivery of Health Care', 'Diverticular Diseases', 'Diverticulitis', 'Diverticulosis, Colonic', 'Humans', 'Risk Factors'] | 31,930,225 | [['E02.760.106', 'N02.421.585.106'], ['C06.405.205.265', 'C06.405.469.158.188'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['N04.590.374', 'N05.300'], ['C06.405.205.282'], ['C06.405.205.282.500'], ['C06.405.469.158.587... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A PTPN11 allele encoding a catalytically impaired SHP2 protein in a patient with a Noonan syndrome phenotype. | The RASopathies are a relatively common group of phenotypically similar and genetically related autosomal dominant genetic syndromes caused by missense mutations affecting genes participating in the RAS/mitogen-activated protein kinase (MAPK) pathway that include Noonan syndrome (NS) and Noonan syndrome with multiple l... | ['Alleles', 'Biocatalysis', 'Child, Preschool', 'Facies', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Noonan Syndrome', 'Phenotype', 'Protein Tyrosine Phosphatase, Non-Receptor Type 11'] | 24,891,296 | [['G05.360.340.024.340.030'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['M01.060.406.448'], ['C23.550.291.812', 'E01.370.600.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C05.660.207.690', 'C14.240.400.787', 'C14.280.400.787', 'C16.131.240.400.784', 'C16.131.621.207.6... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Choice of technique in "difficult" inguinal hernias. Personal experience]. | The authors refer on their positive results in the treatment of so-called difficult inguinal hernias (relapsing or multiple hernias) with the use of prosthetic prolene mesh according to Stoppa's procedure (partly modified) through a preperitoneal approach after a Pfannenstiel's incision. On the other hand recurrent her... | ['Hernia, Inguinal', 'Humans', 'Polypropylenes', 'Postoperative Complications', 'Recurrence', 'Surgical Mesh'] | 2,228,685 | [['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665.590', 'D05.750.716.550', 'D25.720.716.550', 'J01.637.051.720.716.550'], ['C23.550.767'], ['C23.550.291.937'], ['E07.858.708']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Erectile function outcome after bilateral nerve sparing radical prostatectomy: which patients may be left untreated? | INTRODUCTION: Several studies have shown that erectile function (EF) recovery in patients undergoing bilateral nerve sparing radical prostatectomy (BNSRP) improves significantly when phosphodiesterase type 5 inhibitors (PDE5) are administered following surgery.AIM: The aim of this article was to identify patients who m... | ['Adult', 'Aged', 'Erectile Dysfunction', 'Humans', 'Male', 'Middle Aged', 'Penile Erection', 'Penis', 'Phosphodiesterase 5 Inhibitors', 'Prostatectomy', 'Prostatic Neoplasms', 'Recovery of Function'] | 22,240,189 | [['M01.060.116'], ['M01.060.116.100'], ['C12.294.644.486', 'F03.835.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.784.717'], ['A05.360.444.492'], ['D27.505.519.389.735.500'], ['E04.950.774.860.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Designing a social and assistive robot for seniors. | BACKGROUND: The development of social assistive robots is an approach with the intention of preventing and detecting falls among seniors. There is a need for a relatively low-cost mobile robot with an arm and a gripper which is small enough to navigate through private homes.MATERIAL AND METHODS: User requirements of a ... | ['Accidental Falls', 'Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Humans', 'Male', 'Man-Machine Systems', 'Needs Assessment', 'Patient Preference', 'Robotics', 'Self-Help Devices', 'Social Support', 'Sweden', 'User-Computer Interface', 'Utilizat... | 27,220,732 | [['N06.850.135.122'], ['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.412.575', 'J01.293.556.441', 'J01.897.441'], ['I02.594', 'N03.349.380.565', 'N05.300.537'... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Information S... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Biomonitoring and exposure levels of imidacloprid in air of workplace and on skin of workers exposed to pesticides. | The article presents results ofhygienic studies on work conditions in using imidacloprid-based pesticides in agriculture. Analysis covered imidacloprid levels in air of workplace, on skin and in urine of workers. | ['Adult', 'Agriculture', 'Air Pollutants, Occupational', 'Dermatitis, Occupational', 'Female', 'Humans', 'Male', 'Neonicotinoids', 'Nitro Compounds', 'Occupational Exposure', 'Occupational Health', 'Pesticides', 'Risk Management', 'Workplace'] | 30,351,844 | [['M01.060.116'], ['J01.040'], ['D27.888.284.101.268'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C24.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.464'], ['D02.640'], ['N06.850.460.350.600'], ['N01.400.525'], ['D27.720.031.700', 'D27.888.723'], ['N03.219.463.800', 'N04.452.871'], ['N01.824.24... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Randot stereoacuity does not accurately predict ability to perform two practical tests of depth perception at a near distance. | PURPOSE: It is common practice to administer stereopsis tests such as the Randot Stereotest to prospective employees for occupations requiring depth perception. However, there is no evidence that stereoacuity measured with tests such as the Randot Stereotest will predict an individual's ability to perform a depth perce... | ['Adult', 'Depth Perception', 'Female', 'Humans', 'Male', 'Predictive Value of Tests', 'Vision Tests', 'Visual Acuity'] | 16,276,324 | [['M01.060.116'], ['F02.463.593.200', 'F02.463.593.778.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E01.370.380.850'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role, practice and training of unregulated birth workers in Australia: A mixed methods study. | BACKGROUND: In Australia, the provision of homebirth services by unregulated birthworkers (doulas, ex-registered midwives, traditional midwives and lay workers) has increased. Accessing a homebirth with a registered midwife via mainstream services is limited. Concern is growing that new legislation aimed at prohibiting... | ['Australia', 'Female', 'Humans', 'Midwifery', 'Pregnancy', 'Professional Role'] | 29,803,611 | [['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478.676.416'], ['G08.686.784.769'], ['F01.829.316.616.625']] | ['Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[Reconstructive microsurgery in the treatment of brachial plexus injury]. | Experience of treatment of 157 patients with the plexus brachialis (PB) injury was summarized. The author delineates three clinical groups depending on the kind of the PB autoplasty done. High efficacy of the PB autoplasty with the nerves transplants bed plasty using fascial-subcutaneous flap on vascular peduncle was n... | ['Adolescent', 'Adult', 'Aged', 'Brachial Plexus', 'Female', 'Humans', 'Male', 'Microsurgery', 'Middle Aged', 'Reconstructive Surgical Procedures'] | 11,944,273 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A08.800.800.720.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.494', 'E05.591.580'], ['M01.060.116.630'], ['E04.680']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Insulin resistance of denervated rat muscle: a model for impaired receptor-function coupling. | The effect of short-term denervation on the response to insulin was studied in isolated rat soleus and extensor digitorum longus (EDL) muscles 6 and 24 h after severing one sciatic nerve. Impaired insulin sensitivity and response occurred within 6 h postdenervation in solei. After 24 h, EDL of fed and fasted rats and s... | ['Animals', 'Deoxyglucose', 'Epinephrine', 'Glucose', 'Glucose-6-Phosphate', 'Glucosephosphates', 'Glycogen', 'Glycogen Synthase', 'Insulin', 'Insulin Resistance', 'Male', 'Muscle Denervation', 'Muscles', 'Rats', 'Rats, Inbred Strains', 'Receptor, Insulin', 'Sciatic Nerve', 'Time Factors'] | 6,437,249 | [['B01.050'], ['D09.254.229'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['D09.947.875.359.448'], ['D09.894.417.448.500'], ['D09.894.417.448'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D08.811.913.400.450.460.375'], ['D06.472.69... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Childhood risk factors for thin body preoccupation and social pressure to be thin. | OBJECTIVE: Thin body preoccupation and social pressure to be thin (TBPSP) in adolescence are risk factors for the development of full and partial bulimia nervosa and binge eating disorder. This study examined precursors of these potent risk factors.METHOD: A prospective study followed 134 children from birth to 11.0 ye... | ['Body Image', 'Bulimia Nervosa', 'Child', 'Child, Preschool', 'Father-Child Relations', 'Feeding Behavior', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Overweight', 'Peer Group', 'Prospective Studies', 'Risk Factors', 'Social Conformity', 'Thinness'] | 17,242,620 | [['F01.752.747.792.110', 'F02.463.593.112'], ['F03.400.250'], ['M01.060.406'], ['M01.060.406.448'], ['F01.829.263.370.290.110'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C23.888.144.699', 'E01.370.600.115.100.160.120.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Status of domestic wastewater management in relation to drinking-water supply in two states of India. | In India, supply of drinking water, treatment and disposal of domestic wastewater including faecal matter are managed by local bodies. The existing status of water supply, characteristics of domestic wastewater, modes of collection, treatment and disposal system for sewage and faecal matter in 82 municipalities and 4 m... | ['Developing Countries', 'Humans', 'India', 'Sanitary Engineering', 'Sewage', 'Waste Disposal, Fluid', 'Water Supply'] | 10,842,846 | [['I01.615.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['H02.229.656', 'J01.293.821', 'N06.850.780.200.800.800', 'N06.850.860.510'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['J01.293.821.500']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Anaerobic-ion exchange (AN-IX) process for local-scale nitrogen recovery from wastewater. | An anaerobic-ion exchange (AN-IX) process was developed for point-of-origin recovery of nitrogen from household wastewater. The process features upflow solids-blanket anaerobic treatment (ammonification) followed by ammonium ion exchange onto natural zeolite. The AN-IX system is configured as a series of linked upflow ... | ['Ammonium Compounds', 'Anaerobiosis', 'Bioreactors', 'Equipment Design', 'Florida', 'Ion Exchange', 'Nitrogen', 'Waste Disposal, Fluid', 'Waste Water', 'Zeolites'] | 26,253,916 | [['D01.625.062'], ['G02.111.062', 'G03.078'], ['E07.115', 'J01.897.120.115'], ['E05.320'], ['Z01.107.567.875.750.350'], ['G02.437'], ['D01.268.604', 'D01.362.625'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865'], ['D01.056.050.075.975', 'D01.578.725.025.975', 'D01... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals. | The role of genetic polymorphisms in cytochrome (CYP) 2D6 involved in the metabolism of 3,4-methylene-dioxymethamphetamine (MDMA, ecstasy) is unclear. Effects of genetic variants in CYP2D6 on the pharmacokinetics and pharmacodynamic effects of MDMA were characterized in 139 healthy individuals (70 men, 69 women) in a p... | ['Area Under Curve', 'Blood Pressure', 'Cross-Over Studies', 'Cytochrome P-450 CYP2D6', 'Double-Blind Method', 'Female', 'Healthy Volunteers', 'Humans', 'Male', 'N-Methyl-3,4-methylenedioxyamphetamine', 'Polymorphism, Genetic', 'Prospective Studies', 'Serotonin Agents', 'Tissue Distribution'] | 27,253,829 | [['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D08.244.453.005.600', 'D08.244.453.491.372', 'D08.811.682.690.708.170.010.600', 'D08.811.682.690.708.170.450.368', 'D12.776.422.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Understanding adherence to guidelines in the intensive care unit: development of a comprehensive framework. | BACKGROUND: Clinical practice guidelines (CPGs) have been hailed as a useful method of translating evidence into practice. Several CPGs have been published that provide recommendations for feeding patients in the intensive care unit (ICU). Despite a rigorous development process and active dissemination of these guideli... | ['Attitude of Health Personnel', 'Canada', 'Critical Care', 'Guideline Adherence', 'Humans', 'Intensive Care Units', 'Nutrition Therapy', 'Practice Guidelines as Topic'] | 21,097,762 | [['F01.100.050', 'N05.300.100'], ['Z01.107.567.176'], ['E02.760.190', 'N02.421.585.190'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E02.642'], ['N04.761.700.350.650', 'N05.700.350.650']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Renal cell carcinoma with a huge solitary metastasis to the contralateral adrenal gland: a case report. | Renal cell carcinoma (RCC) is capable of metastasizing to several organs. Synchronous isolated contralateral adrenal metastasis of the primary RCC is, however, very rare. Herein we report a case of RCC with a huge solitary metastasis to the contralateral adrenal gland that was surgically treated. We scheduled nephrecto... | ['Adrenal Gland Neoplasms', 'Adrenal Glands', 'Carcinoma, Renal Cell', 'Humans', 'Kidney', 'Kidney Neoplasms', 'Male', 'Middle Aged'] | 19,120,516 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['A06.300.071'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C04.588.945.947.535', 'C12.... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The importance of secondary immune deficiencies in the pathogenesis of dysentery]. | Some immunity indices were studied in patients with acute dysentery. The number of total and active T-lymphocytes, T mu- and T gamma-cells, T-rabbit, T-staphylococcal, B-total and B-lymphocytes forming rosettes with mouse erythrocytes were determined for assessment of the immune status. Changes in the above indices wit... | ['Acute Disease', 'Adult', 'B-Lymphocytes', 'Convalescence', 'Dysentery, Bacillary', 'Female', 'Humans', 'Immunologic Deficiency Syndromes', 'Male', 'Middle Aged', 'Shigella flexneri', 'Shigella sonnei', 'T-Lymphocytes'] | 3,070,808 | [['C23.550.291.125'], ['M01.060.116'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C23.550.291.562'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.673'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Visionary choice of Japanese radiologists and radiological technologists in 21st century]. | Since X-ray CT appeared in radiology practice in the 1970s, there has been rapid progress in imaging modalities such as US, MRI, PET, and PACS. With these new modalities, radiology has strengthened its advantage in medical practice. In earlier times, it was said "ohne Roentgen, keine Medizin". This is still true today,... | ['Humans', 'Radiology', 'Technology, Radiologic', 'Workforce'] | 11,857,952 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.740'], ['E05.920', 'H02.010.850', 'J01.897.891'], ['N04.452.525']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Elevated interleukin-17 and reduced testosterone in bipolar disorder. Relation with suicidal behaviour. | Hormonal imbalance and inflammation are associated with bipolar disorder and suicidal behavior. The present study was designed to assess the levels of testosterone and interleukin-17 and their association with suicidal behavior in patients with bipolar disorder in remission. 41 bipolar disorder cases in remission and 4... | ['Adolescent', 'Adult', 'Bipolar Disorder', 'Case-Control Studies', 'Humans', 'Interleukin-17', 'Male', 'Middle Aged', 'Suicide', 'Testosterone', 'Young Adult'] | 29,979,995 | [['M01.060.057'], ['M01.060.116'], ['F03.084.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.517', 'D12.776.467.374.465.517', 'D23.529.374.465.517'], ['M01.060.116.630'], ['F01.145.126.980.875', 'I01.880.735.856... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Phylogeography of supralittoral rocky intertidal Ligia isopods in the pacific region from central California to central Mexico. | BACKGROUND: Ligia isopods are widely distributed in the Pacific rocky intertidal shores from central California to central Mexico, including the Gulf of California. Yet, their biological characteristics restrict them to complete their life cycles in a very narrow range of the rocky intertidal supralittoral. Herein, we ... | ['Animals', 'California', 'DNA, Mitochondrial', 'DNA, Ribosomal', 'Electron Transport Complex IV', 'Evolution, Molecular', 'Isopoda', 'Mexico', 'Phylogeny'] | 20,657,776 | [['B01.050'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['D13.444.308.283.225'], ['D13.444.308.475'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['G05.045.250', 'G16.075.250'], ['B01.050.500.13... | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Malassezia spp.-specific immunoglobulin E level is a marker for severity of atopic dermatitis in adults. | The significance of allergen-specific IgE as marker for severity of atopic dermatitis is controversial. The aim of this study was to determine the frequency of IgE-mediated sensitisation to food and environmental allergens in 132 children and 67 adults with atopic dermatitis, and its correlation to severity of atopic d... | ['Adult', 'Allergens', 'Antibodies, Fungal', 'Biomarkers', 'Child', 'Child, Preschool', 'Dermatitis, Atopic', 'Female', 'Food Hypersensitivity', 'Humans', 'Immunoglobulin E', 'Infant', 'Malassezia', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Risk Factors', 'Serologic Tests', 'Severity of Illness Index', 'Youn... | 24,696,225 | [['M01.060.116'], ['D23.050.063'], ['D12.776.124.486.485.114.179', 'D12.776.124.790.651.114.179', 'D12.776.377.715.548.114.179'], ['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['C20.543.480.370'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Platelet function after the single administration of buflomedil]. | Earlier investigations have demonstrated that buflomedil, a substance which is successful in the clinical treatment of peripheral vascular disease, exerts an inhibitory effect on ADP-induced aggregation ex vivo and in vitro. In the presented study the effect of buflomedil on platelets is investigated. Clinically widely... | ['Adult', 'Blood Platelets', 'Female', 'Humans', 'Male', 'Platelet Aggregation', 'Platelet Count', 'Platelet Function Tests', 'Pyrrolidines', 'Vasodilator Agents'] | 4,072,227 | [['M01.060.116'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.188.370.687', 'G09.188.390.600.640'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.225.625.625.625', 'E05.200.500.195.107.740', 'E05.200.625.107.700', 'E05.200.625.625.625', 'E05.242.195.1... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Downregulated expression of hepatoma-derived growth factor (HDGF) reduces gallbladder cancer cell proliferation and invasion. | Hepatoma-derived growth factor (HDGF), a heparin-binding growth factor, has a wide range of biological functions, including mitogenic activity and vascular development. Recent studies demonstrated that HDGF also acted as an oncogene with aberrantly increased activity in multiple human cancers; however, little is known ... | ['Cell Growth Processes', 'Cell Line, Tumor', 'Cell Nucleus', 'Chi-Square Distribution', 'Down-Regulation', 'Female', 'Gallbladder Neoplasms', 'Humans', 'Immunohistochemistry', 'Intercellular Signaling Peptides and Proteins', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Invasivenes... | 23,609,195 | [['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.13... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of zinc-binding properties of a novel imidase from Pseudomonas putida YZ-26. | The imidase from Pseudomonas putida YZ-26 consisting of 293-amino acid residues is a novel imidase with four subunits as the holo-enzyme and low molecular weight which is significantly different from known mammalian imidase. This study measured the zinc-binding properties of the imidase using inductively coupled plasma... | ['Amidohydrolases', 'Base Sequence', 'DNA Primers', 'Electrophoresis, Polyacrylamide Gel', 'Protein Binding', 'Protein Conformation', 'Pseudomonas putida', 'Recombinant Proteins', 'Zinc'] | 19,931,221 | [['D08.811.277.087'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['B03.440.400.425.625.625.675', 'B03.660.250.580.590.580'], ['D12.776.828'], ['D01.268... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Plain radiograghs of lumbar spine in patients with low back pain. | Low back pain (LBP) is a common presenting complaint in our hospital in Enugu Nigeria. Three hundred thirty-three radiographs of patients with LBP were studied. A lot of them had bony outgrowths (osteophytes) on the spine. Plain radiograph of the spine is useful in studying these patients' condition.INTRODUCTION: Low b... | ['Adult', 'Aged', 'Female', 'Humans', 'Low Back Pain', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Nigeria', 'Osteophyte', 'Radiography', 'Retrospective Studies'] | 30,293,145 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['Z01.058.290.190.565'], ['C05.116.540.310.800'], ['E01.370.350.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', ... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bacterial periorbital and orbital cellulitis in childhood. | The clinical features, microbiologic data, complications, and treatment in 137 children with periorbital cellulitis and 21 children with orbital cellulitis is presented. Periorbital cellulitis was more frequent (87%) than orbital cellulitis (13%). Periorbital cellulitis is a heterogeneous disease that may complicate tr... | ['Bacterial Infections', 'Cellulitis', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Orbital Diseases', 'Sinusitis'] | 6,866,441 | [['C01.150.252'], ['C01.800.130', 'C01.830.200', 'C17.300.185', 'C23.550.470.756.200'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C11.675'], ['C01.748.749', 'C08.460.692.752', 'C08.730.749', 'C09.603.692.752']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Placental examination with dye injections in post-delivery chorionicity assessment in dichorionic triplet pregnancy. | The incidence of spontaneous triplet pregnancy is approximately 1 in 7000 deliveries. Due to the fact that every presentation of a triplet and higher order pregnancy is associated with high rate of morbidity and preterm delivery, chorionicity and amnionicity remain significant predictive factors which determine specifi... | ['Adult', 'Cesarean Section', 'Chorion', 'Coloring Agents', 'Female', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Natural Childbirth', 'Parturition', 'Pregnancy', 'Pregnancy, Triplet'] | 27,306,295 | [['M01.060.116'], ['E04.520.252.500'], ['A10.615.284.473', 'A16.254.750.473'], ['D27.720.233'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769.490.249'], ['G08.686.784.769.490'], ['G08.686.784.769'], ['G08.686.784.769.545.126']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. | Monoclonal antibody MRK16 was used to determine the location of P-glycoprotein, the product of the multidrug-resistance gene (MDR1), in normal human tissues. The protein was found to be concentrated in a small number of specific sites. Most tissues examined revealed very little P-glycoprotein. However, certain cell typ... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Antibodies, Monoclonal', 'Drug Resistance', 'Epitopes', 'Genes', 'Humans', 'Immunoenzyme Techniques', 'Immunohistochemistry', 'Membrane Glycoproteins', 'Organ Specificity'] | 2,444,983 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G07.690.77... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The natural antioxidant otobaphenol delays the permeability transition of mitochondria and induces their aggregation. | The lignan otobaphenol, (8R,8'R,7R)-4'-hydroxy-5'-methoxy-3,4-methylenedioxy-2',7,8,8'-neolignan, extracted from Virola Aff. Pavonis leaves, completely inhibits at a concentration of 2.5 micro M the Fe(3+)-ascorbate-induced lipoperoxidation of rat liver mitochondria that was determined by oxygen consumption and accumul... | ['Animals', 'Antioxidants', 'Ascorbic Acid', 'Biphenyl Compounds', 'Butylated Hydroxytoluene', 'Calcium', 'Cell Membrane Permeability', 'Ferric Compounds', 'Free Radical Scavengers', 'Intracellular Membranes', 'Lipid Peroxidation', 'Male', 'Membrane Potentials', 'Mitochondria, Liver', 'Mitochondrial Swelling', 'NADP', ... | 12,880,483 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D02.455.426.559.389.185'], ['D02.455.426.559.389.657.239.216'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G03.143.335', 'G04.175'], ['D01.490.100'], ['D27.505.519.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laccase activity in soils: considerations for the measurement of enzyme activity. | Laccases (benzenediol: oxygen oxidoreductases, EC 1.10.3.2) are copper-containing enzymes that catalyze the oxidative conversion of a variety of chemicals, such as mono-, oligo-, and polyphenols and aromatic amines. Laccases have been proposed to participate in the transformation of organic matter and xenobiotics as we... | ['Artifacts', 'Benzopyrans', 'Enzyme Assays', 'Humic Substances', 'Hydrogen-Ion Concentration', 'Kinetics', 'Laccase', 'Mitosporic Fungi', 'Molecular Weight', 'Soil', 'Trametes'] | 22,475,148 | [['E05.047'], ['D03.383.663.283', 'D03.633.100.150'], ['E05.196.427'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.494'], ['B01.300.381'], ['G02.494'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.300.179.120.174.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The tandem complex of BEL and KNOX partners is required for transcriptional repression of ga20ox1. | Summary Two interacting three amino acid loop extension (TALE) proteins of potato, StBEL5 (Solanum tuberosom BEL 5) and POTH1 (potato homeobox 1), mediate developmental processes by regulating phytohormone levels. Overexpression of either partner alone increased tuber yields by lowering gibberellin (GA) levels and incr... | ['Base Sequence', 'Binding Sites', 'DNA, Plant', 'Dimerization', 'Escherichia coli', 'Genes, Plant', 'Homeodomain Proteins', 'Macromolecular Substances', 'Plant Proteins', 'Promoter Regions, Genetic', 'Recombinant Fusion Proteins', 'Repressor Proteins', 'Solanum tuberosum', 'Transcription, Genetic'] | 15,078,330 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D13.444.308.435'], ['G02.206', 'G03.230'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D12.776.260.400'], ['D05'], ['D12.776.765'], ['G02.111.570.080.689.675', 'G05.360.08... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. | We isolated and characterized immunoreactive apolipoprotein B (apoB)-containing lipoproteins from human atherosclerotic plaque and plasma to determine whether very-low-density lipoprotein (VLDL) can enter and become incorporated into the atherosclerotic lesion and how plaque apoB-containing lipoproteins differ from apo... | ['Aged', 'Antibodies', 'Apolipoproteins B', 'Apolipoproteins E', 'Arteriosclerosis', 'Female', 'Humans', 'Immunoelectrophoresis', 'Immunosorbent Techniques', 'Lipoproteins', 'Male', 'Middle Aged', 'Particle Size', 'Triglycerides'] | 7,947,602 | [['M01.060.116.100'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
RNA aptamers specifically interact with the prion protein PrP. | We have isolated RNA aptamers which are directed against the recombinant Syrian golden hamster prion protein rPrP23-231 (rPrPc) fused to glutathione S-transferase (GST). The aptamers did not recognize the fusion partner GST or the fusion protein GST::rPrP90-231 (rPrP27-30), which lacks 67 amino acids from the PrP N ter... | ['Animals', 'Base Sequence', 'Binding Sites', 'Cattle', 'Cricetinae', 'Glutathione Transferase', 'Mice', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Oligoribonucleotides', 'PrP 27-30 Protein', 'RNA-Binding Proteins', 'Recombinant Fusion Proteins', 'Species Specificity', 'Structure-Activity Relationship'] | 9,343,239 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.649.313.992.635.075.250'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Medium for selective isolation of Cryptococcus neoformans. | A medium has been developed that permits the selective recovery of Cryptococcus neoformans from heavily contaminated materials. It employs creatinine as a nitrogen source, diphenyl (C(6)H(5)C(6)H(5)) and chloramphenicol as mold and bacterial inhibitors, and Guizotia abyssinica seed extract as a specific color marker. T... | ['Biphenyl Compounds', 'Chloramphenicol', 'Creatine', 'Cryptococcus', 'Culture Media', 'In Vitro Techniques', 'Seeds'] | 5,907,910 | [['D02.455.426.559.389.185'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['D02.078.370.280', 'D12.125.373'], ['B01.300.381.258', 'B01.300.930.316'], ['D27.720.470.305', 'E07.206'], ['E05.481'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sleep-related hormone secretion in depressed patients. | Among human subjects, sleep is a time of considerable neuro-endocrine activity and the nocturnal secretion of growth hormone is intimately related to the sleep-wake cycle. In contrast, the hypothalamic-pituitary-adrenal axis of entrained individuals shows a circadian pattern of activity with secretion increasing in the... | ['Adrenal Cortex', 'Adult', 'Depressive Disorder', 'Electroencephalography', 'Female', 'Growth Hormone', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Pituitary Gland, Anterior', 'Sleep'] | 4,091,022 | [['A06.300.071.140'], ['M01.060.116'], ['F03.600.300'], ['E01.370.376.300', 'E01.370.405.245'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['M01.060.116.630'], ['A06.300.7... | ['Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Metabolomics reveals the mechanism of (-)-hydroxycitric acid promotion of protein synthesis and inhibition of fatty acid synthesis in broiler chickens. | (-)-Hydroxycitric acid (HCA), a major component of Garcinia cambogia extracts, has been shown to suppress BW gain and fat accumulation in animals and humans. However, the mechanism remains unknown. In this study, gas chromatography-mass spectrometry was used to analyse serum metabolites, and principal component analysi... | ['Adipogenesis', 'Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Chickens', 'Citrates', 'Diet', 'Dietary Supplements', 'Dose-Response Relationship, Drug', 'Fatty Acids', 'Garcinia cambogia', 'Gene Expression Regulation', 'Humans', 'Metabolomics', 'Plant Extracts', 'Protein Biosynthesis'] | 28,877,777 | [['G04.152.149'], ['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D02.241.081.901.434'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['G07.690.773.875', 'G07.690.936.500'], ['D10.251'], ['B01.650.940.800.575.912... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinical features and management issues in Mowat-Wilson syndrome. | Mowat-Wilson syndrome (MWS) is a relatively newly described multiple congenital anomaly/mental retardation syndrome. Haploinsufficiency of a gene termed ZFHX1B (also known as SIP1) on chromosome 2 is responsible for this condition, and clinical genetic testing for MWS recently became available. The majority of reports ... | ['Abnormalities, Multiple', 'Adolescent', 'Adult', 'Agenesis of Corpus Callosum', 'Child', 'Child, Preschool', 'Craniofacial Abnormalities', 'Female', 'Hirschsprung Disease', 'Homeodomain Proteins', 'Humans', 'Infant', 'Infant, Newborn', 'Intellectual Disability', 'Language Development Disorders', 'Male', 'Pulmonary Ar... | 17,103,451 | [['C16.131.077'], ['M01.060.057'], ['M01.060.116'], ['C10.500.034', 'C16.131.666.034', 'C23.300.008'], ['M01.060.406'], ['M01.060.406.448'], ['C05.660.207', 'C16.131.621.207'], ['C06.198.439', 'C06.405.469.158.701.439', 'C16.131.314.439'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Methadone in man: pharmacokinetic and excretion studies in acute and chronic treatment. | The biologic disposition of methadone in acute and during chronic administration was studied in 12 human volunteers. In the acute study a biexponential methadone plasma level decay was observed. The acute primary half-life (t1/2) of 14.3 hr in combination with the acute secondary t1/2 of 54.8 hr were longer than the si... | ['Adult', 'Feces', 'Half-Life', 'Humans', 'Kinetics', 'Male', 'Methadone', 'Pupil', 'Time Factors'] | 1,149,368 | [['M01.060.116'], ['A12.459'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D02.522.675'], ['A09.371.060.450.780', 'A09.371.894.513.780'], ['G01.910.857']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transdermal evaporation delivery system of praziquantel for schistosomiasis japonicum chemotherapy. | A transdermal evaporation delivery system (TEDS) of praziquantel (PZQ) was developed by selecting ethylene glycol monophenyl ether as a nonvolatile component solvent and ethanol as a volatile component solvent to control efficiently the transmission and morbidity of the global schistosomiasis, providing a convenient ad... | ['Administration, Cutaneous', 'Administration, Oral', 'Animals', 'Anthelmintics', 'Biological Availability', 'Chemistry, Pharmaceutical', 'Disease Models, Animal', 'Drug Compounding', 'Drug Delivery Systems', 'Ethanol', 'Ethylene Glycols', 'Permeability', 'Praziquantel', 'Rabbits', 'Schistosomiasis japonica', 'Skin', '... | 21,319,162 | [['E02.319.267.120.060'], ['E02.319.267.100'], ['B01.050'], ['D27.505.954.122.250.075'], ['G03.787.151', 'G07.690.725.129'], ['H01.158.703.007', 'H01.181.466'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.916.270'], ['E02.319.300'], ['D02.033.375'], ['D02.033.455.250'], ['G02.723'], ['D03.633.100.531.690'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
In vitro response of lymphocytes from bronchoalveolar lavage fluid and peripheral blood to mitogen stimulation during natural maedi-visna virus infection. | To investigate the effects of maedi-visna virus (MVV) infection on cell-mediated immunity, the in vitro response of bronchoalveolar lavage fluid (BALF) and peripheral blood (BP) lymphocytes (PBL) to exogenous mitogen was analysed. BALF and PBL from control (n = 9) and MVV-infected (n = 7) animals were cultured fro 3 da... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cattle', 'Concanavalin A', 'Female', 'In Vitro Techniques', 'Lymphocyte Activation', 'Lymphocytes', 'Macrophages, Alveolar', 'Pneumonia, Progressive Interstitial, of Sheep', 'Receptors, Antigen, T-Cell, gamma-delta'... | 8,588,346 | [['B01.050'], ['E05.927.100.500'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['B01.050.150.900.649.313.500.380.271'], ['D12.776.503.499.500', 'D12.776.765.678.500']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simulation of paretic gait in normal subjects by loading the ankles. | Normal subjects were loaded with increasing weights (2-6 kg) applied around the ankles. During these conditions stride length increased in relation to velocity. The percentage duration of single support in relation to stride duration increased. Provided the same load was applied around both ankles increase was symmetri... | ['Adolescent', 'Adult', 'Ankle', 'Female', 'Gait', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Muscles'] | 4,059,887 | [['M01.060.057'], ['M01.060.116'], ['A01.378.610.050'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['A02.633', 'A10.690']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of functional synergies for speech motor coordination in childhood and adolescence. | Adults produce rapid, interleaved sequences of speech sounds by controlling the relative motions in time and space of the oral articulators. The control and coordination of these effectors appear to be automatic, effortless, and usually error free. If speech production is viewed within the framework of classical motor ... | ['Adolescent', 'Adult', 'Automatism', 'Child', 'Child Development', 'Child Language', 'Child, Preschool', 'Cross-Sectional Studies', 'Cues', 'Female', 'Humans', 'Male', 'Motor Skills', 'Muscle, Skeletal', 'Speech'] | 15,229,873 | [['M01.060.057'], ['M01.060.116'], ['F02.463.425.179.149'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['F01.525.200.310.250'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808.26... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Proteomic identification of actin-derived oligopeptides in dry-cured ham. | An intense proteolysis of muscle proteins, mainly due to the action of endogenous proteolytic enzymes, has been reported to occur during the processing of dry-cured ham. This gives rise to an important generation of free amino acids and peptides of small size that contribute directly or indirectly to flavor characteris... | ['Actins', 'Amino Acid Sequence', 'Animals', 'Meat', 'Molecular Sequence Data', 'Oligopeptides', 'Proteomics', 'Swine'] | 17,371,039 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G07.203.300.600', 'J02.500.600'], ['L01.453.245.667'], ['D12.644.456'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Hypoxia-driven proliferation of embryonic neural stem/progenitor cells--role of hypoxia-inducible transcription factor-1alpha. | We recently reported that intermittent hypoxia facilitated the proliferation of neural stem/progenitor cells (NPCs) in the subventricule zone and hippocampus in vivo. Here, we demonstrate that hypoxia promoted the proliferation of NPCs in vitro and that hypoxia-inducible factor (HIF)-1alpha, which is one of the key mol... | ['Animals', 'Bromodeoxycytidine', 'Cell Hypoxia', 'Cell Proliferation', 'Cells, Cultured', 'Embryonic Stem Cells', 'Female', 'Gene Expression Regulation', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Neurons', 'RNA Interference', 'Rats', 'Rats, Wistar'] | 18,341,590 | [['B01.050'], ['D03.383.742.680.245.500.250', 'D13.570.230.329.100', 'D13.570.685.245.500.250'], ['G03.197.300', 'G04.270.300'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A11.872.700.250'], ['G05.308'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['A08.675', 'A11.671'], ['G05.308.203.374.790'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interaction with the game and motivation among players of massively multiplayer online role-playing games. | Knowledge about users interacting with Massively Multiplayer Online Role-Playing Games (MMORPG) is fundamental in order to prevent their potential negative effects on behavior. For this reason, the present study analyzed the relationship between styles of play and motivations. An online questionnaire asking for socio-d... | ['Achievement', 'Adolescent', 'Adult', 'Behavior, Addictive', 'Dissociative Disorders', 'Exploratory Behavior', 'Female', 'Humans', 'Internet', 'Interpersonal Relations', 'Male', 'Motivation', 'Recreation', 'Role Playing', 'Social Behavior', 'Surveys and Questionnaires', 'Video Games', 'Young Adult'] | 23,866,239 | [['F01.658.059', 'F02.784.629.054'], ['M01.060.057'], ['M01.060.116'], ['F01.145.527.100.120'], ['F03.300'], ['F01.145.387', 'F01.658.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F01.829.401'], ['F01.658', 'F01.752.543.500.750'], ['I03.450.642'], ['E02.190.525.781.653', 'F04.754.86... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
"Vague and artificial": the historically elusive distinction between pure and applied science. | This essay argues for the historicity of applied science as a contested category within laissez-faire Victorian British science. This distinctively pre-twentieth-century notion of applied science as a self-sustaining, autonomous enterprise was thrown into relief from the 1880s by a campaign on the part of T. H. Huxley ... | ['History, 19th Century', 'History, 20th Century', 'Science', 'Technology', 'Terminology as Topic', 'United Kingdom', 'World War I'] | 23,286,193 | [['K01.400.504.937'], ['K01.400.504.968'], ['H01.770'], ['J01.897'], ['L01.559.598.400'], ['Z01.542.363'], ['I01.880.735.950.250.968', 'K01.400.504.968.900']] | ['Humanities [K]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 |
Stereotypical alterations in cortical patterning are associated with maternal illness-induced placental dysfunction. | We have previously shown in mice that cytokine-mediated damage to the placenta can temporarily limit the flow of nutrients and oxygen to the fetus. The placental vulnerability is pronounced before embryonic day 11, when even mild immune challenge results in fetal loss. As gestation progresses, the placenta becomes incr... | ['Animals', 'Cerebral Cortex', 'Cognition', 'Cognition Disorders', 'DNA-Binding Proteins', 'Female', 'Interneurons', 'Matrix Attachment Region Binding Proteins', 'Mental Disorders', 'Mice', 'Mice, Inbred C57BL', 'Neurogenesis', 'Placenta', 'Placenta Diseases', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Repres... | 24,155,294 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['F02.463.188'], ['F03.615.250'], ['D12.776.260'], ['A08.675.358', 'A11.671.358'], ['D12.776.260.532'], ['F03'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['G04.152.912', 'G07.345.500.32... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of enfonidipine hydrochloride in dogs with experimental supraventricular tachyarrhythmia. | It is required not to increase the ventricular rate and to preserve the ventricular systolic function in treating supraventricular tachyarrhythmia (SVTA). The objective of this study is to investigate whether or not Efonidipine hydrochloride (EH), a T and L dual type Ca(2+) channel blocker, suppresses the increasing ve... | ['Animals', 'Antihypertensive Agents', 'Calcium Channel Blockers', 'Dihydropyridines', 'Dog Diseases', 'Dogs', 'Heart Rate', 'Humans', 'Nitrophenols', 'Organophosphorus Compounds', 'Systole', 'Tachycardia', 'Tachycardia, Supraventricular', 'Treatment Outcome'] | 20,179,390 | [['B01.050'], ['D27.505.954.411.162'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D03.383.725.203'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.657.566', 'D02.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Green synthesis of nanocomposites consisting of silver and protease alpha chymotrypsin. | The synergy of ultrasonication and the exposure to light radiation was found to be necessary in the formation of nanocomposites of silver and a protease alpha chymotrypsin. The reaction was carried out in aqueous medium and the process took just less than 35 min. Ultrasonication alone formed very negligible number of n... | ['Acoustics', 'Chymotrypsin', 'Fluorescence', 'Hydrogen-Ion Concentration', 'Light', 'Microscopy, Electron, Transmission', 'Nanocomposites', 'Scattering, Radiation', 'Silver', 'Surface Plasmon Resonance', 'Time Factors', 'Ultraviolet Rays'] | 23,411,166 | [['H01.671.031'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G02.300'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512.150'], ['E05.196.822', 'G01.8... | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Influence of acute tryptophan depletion on gastric sensorimotor function in humans. | Peripheral serotonin (5-hydrodytryptamine; 5-HT) is involved in the regulation of gastrointestinal motility and sensation, whereas centrally it plays a role in mood regulation. A dysfunctional serotonergic system may provide a plausible link between functional dyspepsia symptoms and its high psychosocial comorbidity su... | ['Adult', 'Anxiety', 'Compliance', 'Depression', 'Diagnostic Techniques, Digestive System', 'Double-Blind Method', 'Dyspepsia', 'Eating', 'Female', 'Gastric Mucosa', 'Gastrointestinal Motility', 'Gastrointestinal Tract', 'Humans', 'Intestinal Mucosa', 'Male', 'Sensation', 'Serotonin', 'Stomach', 'Time Factors', 'Trypto... | 20,884,888 | [['M01.060.116'], ['F01.470.132'], ['G01.374.590.210'], ['F01.145.126.350'], ['E01.370.372'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C23.888.821.236'], ['G07.203.650.283', 'G10.261.330'], ['A03.556.875.875.440', 'A10.615.550.291'], ['G10.261.360'], ['A03.556'], ['B01.050... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Implant dentistry at the focus of liability lawsuits. | PURPOSE: In recent years, the growing readiness on the part of dental patients to take legal action has resulted in an increasing number of medical liability lawsuits. The aim of this retrospective analysis was to highlight aspects of these lawsuits of special significance, to subject them to both qualitative and quant... | ['Compensation and Redress', 'Dental Implantation, Endosseous', 'Dental Records', 'Expert Testimony', 'Germany', 'Humans', 'Informed Consent', 'Liability, Legal', 'Malpractice', 'Oral Surgical Procedures', 'Retrospective Studies', 'Risk Management'] | 15,214,222 | [['I01.880.604.583.050', 'N03.219.075', 'N03.706.535.125'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['E05.318.308.940.375', 'L01.399.250.900.375', 'N04.452.859.341', 'N05.715.360.300.715.330', 'N06.850.520.308.940.375'], ['I01.880.604.583.232', 'N03.706.535.253'], ['Z01.542... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Characterization of the prostate-specific antigen gene: a novel human kallikrein-like gene. | Using Prostate-specific Antigen cDNA fragments as hybridization probes a clone containing the information for the gene encoding Prostate-specific Antigen was isolated form a human genomic DNA library. The complete gene (about 6 kb) was sequenced and shown to be composed of four introns and five exons. Two major transcr... | ['Amino Acid Sequence', 'Antigens, Neoplasm', 'Base Sequence', 'DNA Probes', 'Exons', 'Humans', 'Introns', 'Kallikreins', 'Male', 'Molecular Sequence Data', 'Nucleic Acid Hybridization', 'Prostate', 'Prostate-Specific Antigen', 'Regulatory Sequences, Nucleic Acid', 'Repetitive Sequences, Nucleic Acid', 'Sequence Homolo... | 2,466,464 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.285'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Menarchal timing in type 1 diabetes through the last 4 decades. | OBJECTIVE: We sought to examine whether age at menarche has changed over the past 4 decades by comparing age at menarche by year of diagnosis with type 1 diabetes.RESEARCH DESIGN AND METHODS: This work consisted of a cross-sectional study of age at menarche in two cohorts: adolescents (ages 11-24 years, n = 228) and ad... | ['Adolescent', 'Adult', 'Child', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Menarche', 'Middle Aged', 'Young Adult'] | 20,843,975 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760.410', 'G08.686.841.374.410'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ozone uptake, water loss and carbon exchange dynamics in annually drought-stressed Pinus ponderosa forests: measured trends and parameters for uptake modeling. | This paper describes 3 years of physiological measurements on ponderosa pine (Pinus ponderosa Dougl. ex Laws.) growing along an ozone concentration gradient in the Sierra Nevada, California, including variables necessary to parameterize, validate and modify photosynthesis and stomatal conductance algorithms used to est... | ['California', 'Carbon', 'Cell Respiration', 'Circadian Rhythm', 'Dehydration', 'Models, Biological', 'Ozone', 'Photosynthesis', 'Pinus ponderosa', 'Plant Transpiration', 'Seasons', 'Soil', 'Trees', 'Weather'] | 14,704,137 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['D01.268.150'], ['G03.197', 'G04.270'], ['G07.180.562.190'], ['C18.452.950.179', 'C23.550.274'], ['E05.599.395'], ['D01.362.670.600'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['B01.650.940.80... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Beta-lactam biosynthesis in a gram-negative eubacterium: purification and characterization of isopenicillin N synthase from Flavobacterium sp. strain SC 12.154. | The occurrence, localization, and extraction of isopenicillin N-synthase (IPNS) were investigated in the gram-negative low-level beta-lactam producer Flavobacterium sp. strain SC 12.154, which forms deacetoxycephalosporin and excretes the cephabacin 7-formamidocephalosporin. IPNS was detected with anti-IPNS antibodies ... | ['Blotting, Western', 'Cephalosporins', 'Chromatography, High Pressure Liquid', 'Disulfides', 'Enzymes', 'Fermentation', 'Flavobacterium', 'Hydrogen-Ion Concentration', 'Kinetics', 'Molecular Weight', 'Oxidoreductases', 'Sulfhydryl Compounds', 'Temperature', 'Time Factors', 'beta-Lactamases'] | 2,793,834 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['E05.196.181.400.300'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D08.811'], ['G02.111.158.249', 'G03.191.249'], ['B03.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Surgical approaches to the calcaneus and the sural nerve: There is no safe zone. | BACKGROUND: Sural nerve related symptoms following the extensile lateral approach to the calcaneus (ELA) and the sinus tarsi approach (STA) are a known postoperative complication despite awareness of the course the sural nerve. While the main trunk of the sural nerve and its location relative to the approaches have bee... | ['Cadaver', 'Calcaneus', 'Female', 'Foot', 'Fracture Fixation, Internal', 'Heel', 'Humans', 'Intra-Articular Fractures', 'Male', 'Peripheral Nerve Injuries', 'Postoperative Complications', 'Sural Nerve'] | 29,409,272 | [['C23.550.260.224'], ['A02.835.232.043.300.710.300'], ['A01.378.610.250'], ['E04.555.300.300'], ['A01.378.610.250.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.404.505'], ['C10.668.829.712', 'C10.900.575', 'C26.915.650'], ['C23.550.767'], ['A08.800.800.720.450.760.820.820']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
During exercise in the cold increased availability of plasma nonesterified fatty acids does not affect the pattern of substrate oxidation. | Exercise in the cold was investigated to establish if the relative contribution of fat to energy expenditure is affected by the increased availability of circulating nonesterified fatty acids (NEFA). Seven men after an overnight fast cycled at approximately 70% of peak oxygen uptake for 60 minutes at an ambient tempera... | ['Adult', 'Algorithms', 'Anaerobic Threshold', 'Blood Gas Analysis', 'Blood Glucose', 'Body Temperature', 'Carbohydrate Metabolism', 'Cold Temperature', 'Exercise', 'Exercise Test', 'Fats', 'Fatty Acids, Nonesterified', 'Glycerol', 'Hematocrit', 'Hemoglobins', 'Humans', 'Kinetics', 'Male', 'Muscle, Skeletal', 'Oxidatio... | 14,767,872 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['G03.680.110', 'G11.427.680.134'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['D09.947.875.359.448.500'], ['E01.370.600.875.374', 'G07.110'], ['G02.111.158', 'G03.191'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.71... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Remote ischemic conditioning in septic shock (RECO-Sepsis): study protocol for a randomized controlled trial. | BACKGROUND: Septic shock is a major public health problem that is associated with up to 50% mortality. Unfavorable outcomes are mainly attributed to multiple organ failure (MOF) resulting from an uncontrolled inflammatory response and ischemia-reperfusion processes. REmote ischemic COnditioning (RECO) is a promising in... | ['Humans', 'Ischemic Preconditioning', 'Multiple Organ Failure', 'Myocardial Reperfusion Injury', 'Outcome Assessment, Health Care', 'Prospective Studies', 'Randomized Controlled Trials as Topic', 'Research Design', 'Sample Size', 'Shock, Septic'] | 31,118,101 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.592', 'E05.516'], ['C23.550.835.525'], ['C14.280.238.615', 'C14.280.647.625', 'C14.907.585.625', 'C14.907.725.600', 'C23.550.767.877.500'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Polydatin enhances the chemosensitivity of osteosarcoma cells to paclitaxel. | Despite improvements in the prognosis of osteosarcoma patients, chemotherapy fails in a considerable number of cases due to drug resistance. The development of novel agents may enhance chemosensitivity. This study explored the anticancer function of polydatin and its ability-in combination with paclitaxel-to overcome d... | ['Apoptosis', 'Caspase 3', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Drug Resistance, Neoplasm', 'Gene Expression Regulation, Neoplastic', 'Glucosides', 'Humans', 'Neoplasm Proteins', 'Osteosarcoma', 'Paclitaxel', 'Stilbenes'] | 31,106,479 | [['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.984.395'], ['... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid determination of renal filtration function using an optical ratiometric imaging approach. | Glomerular filtration rate (GFR), which measures the amount of plasma filtered through the kidney within a given time, is an essential and clinically important indicator of kidney function. Here, we report a new ratiometric measurement technique based on intravital fluorescence microscopy that allows rapid evaluations ... | ['Algorithms', 'Animals', 'Dextrans', 'Diagnostic Imaging', 'Fluorescein-5-isothiocyanate', 'Fluorescent Dyes', 'Glomerular Filtration Rate', 'Image Processing, Computer-Assisted', 'Insulin', 'Ischemia', 'Kidney', 'Kinetics', 'Ligation', 'Male', 'Microscopy, Fluorescence', 'Nephrectomy', 'Plasma', 'Rats', 'Rats, Spragu... | 17,311,910 | [['G17.035', 'L01.224.050'], ['B01.050'], ['D05.750.078.562.272', 'D09.698.365.272'], ['E01.370.350'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.400', 'D04.711.347.400'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E01.370.390.400.300', 'G08.852.357'], ['L01.224.308'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Increased right ventricular Septomarginal trabeculation mass is a novel marker for pulmonary hypertension: comparison with ventricular mass index and right ventricular mass. | OBJECTIVE: : To prospectively evaluate the cardiac magnetic resonance (MR) imaging-derived measurement of right ventricular (RV) septomarginal trabeculation (SMT) mass as a noninvasive marker for pulmonary hypertension (PH), compared with the ventricular mass index (VMI = RV mass/left ventricular mass) and RV mass.MATE... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers', 'Cardiac Catheterization', 'Confidence Intervals', 'Female', 'Health Status Indicators', 'Heart Ventricles', 'Hemodynamics', 'Humans', 'Hypertension, Pulmonary', 'Hypertrophy, Right Ventricular', 'Logistic Models', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle ... | 21,577,127 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['A07.541.560'], ['G09.330.380... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunohistochemical demonstration of estradiol in the guinea pig ovary. | Histochemical study of estradiol in the guinea pig ovary using RIA antiserum revealed specific estradiol fluorescence in theca interna cells and in single cells of atretic follicles. The fluorescence intensity was highest in the estrus phase. | ['Animals', 'Estradiol', 'Estrus', 'Female', 'Fluorescent Antibody Technique', 'Guinea Pigs', 'Histocytochemistry', 'Ovarian Follicle', 'Ovary', 'Theca Cells'] | 3,899,734 | [['B01.050'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.992.550'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Layer-by-layer technique as a new approach to produce nanostructured films containing phospholipids as transducers in sensing applications. | Phospholipids are widely used as mimetic systems to exploit interactions involving biological membranes and pharmacological drugs. In this work, the layer-by-layer (LbL) technique was used as a new approach to produce multilayered thin films containing biological phospholipids applied as transducers onto Pt interdigita... | ['Biosensing Techniques', 'Microscopy, Atomic Force', 'Molecular Structure', 'Nanostructures', 'Nanotechnology', 'Pharmaceutical Preparations', 'Phospholipids', 'Spectrophotometry', 'Transducers'] | 19,161,323 | [['E05.601.043'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['G02.111.570', 'G02.466'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['D26'], ['D10.570.755'], ['E05.196.712.726', 'E05.196.867.826'], ['E07.305.812']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Iodide uptake by negatively charged clay interlayers? | Understanding iodide interactions with clay minerals is critical to quantifying risk associated with nuclear waste disposal. Current thought assumes that iodide does not interact directly with clay minerals due to electrical repulsion between the iodide and the negatively charged clay layers. However, a growing body of... | ['Adsorption', 'Aluminum Silicates', 'Clay', 'Iodides', 'Iodine Radioisotopes', 'Radioactive Waste', 'Soil Pollutants, Radioactive'] | 26,057,987 | [['G01.030', 'G02.020'], ['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D20.721.250', 'G01.311.820.250', 'G16.500.275.815.250', 'N06.230.600.250'], ['D01.248.497.158.490', 'D01.475.410'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D20.693.638', 'D20... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage. | The transcriptional coactivator Yes-associated protein (YAP) has been shown to interact with and to enhance p73-dependent apoptosis in response to DNA damage. Here, we show that YAP requires the promyelocytic leukemia gene (PML) and nuclear body localization to coactivate p73. YAP imparts selectivity to p73 by promotin... | ['Acetylation', 'Antibiotics, Antineoplastic', 'Apoptosis Regulatory Proteins', 'Cell Cycle Proteins', 'Cisplatin', 'DNA Damage', 'DNA-Binding Proteins', 'Doxorubicin', 'Genes, Reporter', 'Genes, Tumor Suppressor', 'Humans', 'Neoplasm Proteins', 'Nuclear Proteins', 'Promyelocytic Leukemia Protein', 'Proteins', 'Trans-A... | 15,893,728 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D27.505.954.248.106'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.776.167'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G05.200'], ['D12.776.260'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G05.360.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid. | A new class of products in which the phenol group of salicylic acid is linked to alkanoyl moieties bearing nitrooxy functions has been synthesized and studied for their polyvalent actions. The products were stable in acid and neutral media, while they were hydrolyzed in human serum. Their half-lives were dependent upon... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Aorta, Thoracic', 'Aspirin', 'Carrageenan', 'Drug Evaluation, Preclinical', 'Edema', 'Humans', 'Hydrolysis', 'Male', 'Molecular Structure', 'Nitric Oxide Donors', 'Nitro Compounds', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Rats', 'Rats, Wistar',... | 18,293,898 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['A07.015.114.056.372'], ['D02.455.426.559.389.657.410.595.176'], ['D09.698.152'], ['E05.290.750', 'E05.337.550'], ['C23.888.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['G02.111.570', 'G02.466'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Calcific tendinitis of the vastus lateralis muscle. A report of three cases. | Three cases of calcific tendinitis occurring at an unusual site (vastus lateralis tendon) are described. Findings on conventional radiography and computed tomography together with the clinical history are characteristic for this disorder and reflect its natural evolution. The actual role of magnetic resonance imaging s... | ['Aged', 'Calcinosis', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Tendinopathy', 'Thigh', 'Tomography, X-Ray Computed'] | 2,000,500 | [['M01.060.116.100'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C05.651.869', 'C26.874.800'], ['A01.378.610.750'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of training on the biokinematics in trotting Andalusian horses. | The aim of this study was to determine the influence of a 10-month training programme on the linear, temporal and angular characteristics of the fore and hind limbs at the trot in the Andalusian horse, using standard computer-aided videography. Sixteen male Andalusian horses were observed before and after training. Six... | ['Animals', 'Biomechanical Phenomena', 'Forelimb', 'Gait', 'Horses', 'Image Processing, Computer-Assisted', 'Male', 'Physical Conditioning, Animal', 'Rhombencephalon', 'Spain', 'Videotape Recording'] | 11,085,468 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['A13.395'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.984.235.472'], ['L01.224.308'], ['G11.427.410.698.277.280'], ['A08.186.211.132.810'], ['Z01.542.846'], ['J01.897.280.500.846.734', 'J01.897.280.500.898.840', 'L01.178.590.875.840', 'L01.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Pediatric burn injuries in South Africa: a 15-year analysis of hospital data. | INTRODUCTION: Burns are a significant burden of pediatric injuries, particularly in low and middle-income countries, were more than 90% of burn-related pediatric deaths occur. This study explores pediatric burn-related injuries over a fifteen year time period in South Africa through an analysis of a pediatric trauma su... | ['Accidents, Home', 'Age Distribution', 'Burns', 'Child', 'Child, Preschool', 'Data Interpretation, Statistical', 'Female', 'Hospitalization', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Policy Making', 'Retrospective Studies', 'Sentinel Surveillance', 'South Africa'] | 23,415,388 | [['N06.850.135.217'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['C26.200'], ['M01.060.406'], ['M01.060.406.448'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.556.437'], ['B01.050.150.900.649.... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The pathobiological behaviors and prognosis associated with Japanese gastric adenocarcinomas of pure WHO histological subtypes. | Japan is a high-risk region for gastric carcinoma with a comparatively early stage and favorable prognosis. To clarify the pathobiological behaviors and prognosis of Japanese gastric adenocarcinoma, we analyzed the clinicopathological characteristics of different WHO subtypes of carcinomas. The expression of ki-67, CPP... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Papillary', 'Carcinoma, Signet Ring Cell', 'Female', 'Fluorescent Antibody Technique, Direct', 'Gastrectomy', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Stomach Neoplasms', 'Survival Rate', 'Tissue... | 20,183,797 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.240.300', 'E05.200.500.607.512.240.300', 'E05.200.750... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Isolated central nervous system relapse during cytologic and molecular hematologic remission in two patients with acute promyelocytic leukemia. | Extramedullary involvement in the absence of bone marrow disease is rare in patients with acute promyelocytic leukemia (APL). We report two patients with APL who had central nervous system (CNS) relapse without evidence of cytologic and molecular disease of bone marrow after all-trans-retinoic acid (ATRA) treatment. Bo... | ['Adult', 'Central Nervous System Neoplasms', 'Humans', 'Leukemia, Promyelocytic, Acute', 'Male', 'Recurrence', 'Remission Induction', 'Treatment Outcome', 'Tretinoin'] | 17,852,441 | [['M01.060.116'], ['C04.588.614.250', 'C10.551.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275.700'], ['C23.550.291.937'], ['E02.860'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['D02.455.326.271.665.202.495.818.500', 'D02.455.426.392.368.367.379.249.700.860.500', ... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
DNA repair synthesis in the pancreatic islets of streptozotocin-treated mice. | We have investigated the ability of the diabetogenic drug streptozotocin (SZ) to induce DNA repair synthesis following DNA lesions in the cells of the islets of Langerhans of mice. Following intravenous injection of SZ, the pancreatic islets were isolated and incubated with tritiated thymidine. The incorporation of the... | ['Animals', 'Blood Glucose', 'DNA Repair', 'DNA Replication', 'Diabetes Mellitus, Experimental', 'Islets of Langerhans', 'Kinetics', 'Male', 'Mice', 'Mice, Inbred Strains', 'Streptozocin'] | 2,933,209 | [['B01.050'], ['D09.947.875.359.448.500'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A03.734.414', 'A06.300.414'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib. | The chemopreventive effects of three agents, rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib, were tested on mammary tumor development arising in p53-null mammary epithelium. The rexinoid bexarotene was the most efficacious inhibitor as it reduced mammary tumor development by 75% in virgin mice ... | ['Animals', 'Anticarcinogenic Agents', 'Bexarotene', 'Celecoxib', 'Cyclooxygenase Inhibitors', 'Disease Models, Animal', 'ErbB Receptors', 'Female', 'Gefitinib', 'Immunoenzyme Techniques', 'Incidence', 'Mammary Glands, Animal', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Inbred BALB C', 'Mice, Knockout', 'Pyrazol... | 19,174,577 | [['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D02.455.426.559.847.638.960.423', 'D04.615.638.960.423'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.030.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Propensity Score-Based Analysis of Percutaneous Closure Versus Medical Therapy in Patients With Cryptogenic Stroke and Patent Foramen Ovale: The IPSYS Registry (Italian Project on Stroke in Young Adults). | BACKGROUND: We sought to compare the benefit of percutaneous closure to that of medical therapy alone for the secondary prevention of embolism in patients with patent foramen ovale (PFO) and otherwise unexplained ischemic stroke, in a propensity scored study.METHODS AND RESULTS: Between 2000 and 2012, we selected conse... | ['Adolescent', 'Adult', 'Age Factors', 'Brain Ischemia', 'Cardiac Catheterization', 'Cardiovascular Agents', 'Chi-Square Distribution', 'Embolism, Paradoxical', 'Female', 'Foramen Ovale, Patent', 'Humans', 'Intracranial Embolism', 'Italy', 'Male', 'Middle Aged', 'Propensity Score', 'Proportional Hazards Models', 'Regis... | 27,582,111 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['D27.505.954.411'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C14.907.355.590.400'], ['C14.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of thyroidectomy of immature male chickens on circulating thyroid hormones and on response to thyroid-stimulating hormone and chronic cold exposure. | Previous studies in the author's laboratory established that thyroidectomized (Tx) immature male chickens had significant levels of circulating thyroid hormones, and it was proposed that extrathyroidal tissue might be present. Three experiments were conducted to further investigate this possibility. In all experiments,... | ['Aging', 'Animals', 'Chickens', 'Cold Temperature', 'Male', 'Thyroidectomy', 'Thyrotropin', 'Thyroxine', 'Triiodothyronine'] | 2,704,673 | [['G07.345.124'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E04.270.856'], ['D06.472.699.631.525.883', 'D12.644.548.691.525.883'], ['D06.472.931.8... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
TP53 promoter methylation in primary glioblastoma: relationship with TP53 mRNA and protein expression and mutation status. | Reduced expression of TP53 by promoter methylation has been reported in several neoplasms. It remains unclear whether TP53 promoter methylation is associated with reduced transcriptional and protein expression in glioblastoma (GB). The aim of our work was to study the impact of TP53 methylation and mutations on TP53 mR... | ['Base Sequence', 'DNA Methylation', 'DNA Primers', 'Epigenesis, Genetic', 'ErbB Receptors', 'Female', 'Glioblastoma', 'Humans', 'Immunohistochemistry', 'Male', 'Molecular Sequence Data', 'Mutation', 'Poland', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Reverse Transcriptase P... | 24,506,545 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.203'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['C04.557.465.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Methylation of translation elongation factor 1A by the METTL10-like See1 methyltransferase facilitates tombusvirus replication in yeast and plants. | Replication of tombusviruses and other plus-strand RNA viruses depends on several host factors that are recruited into viral replicase complexes. Previous studies have shown that eukaryotic translation elongation factor 1A (eEF1A) is one of the resident host proteins in the highly purified tombusvirus replicase complex... | ['Host-Pathogen Interactions', 'Methylation', 'Methyltransferases', 'Peptide Elongation Factor 1', 'Plant Proteins', 'Protein Binding', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Tobacco', 'Tombusvirus', 'Viral Proteins', 'Virus Replication'] | 24,314,635 | [['G06.462', 'G16.527.200'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D08.811.913.555.500'], ['D08.811.277.040.330.300.100.101', 'D12.776.157.325.150.101', 'D12.776.835.700.350.101'], ['D12.776.765'], ['G02.111.679', 'G03.808'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sweet potato [Ipomoea batatas (L.) Lam.] cultivated as tuber or leafy vegetable supplier as affected by elevated tropospheric ozone. | Sweet potato cultivars respond differently to elevated tropospheric ozone concentrations of ca. 130 mug m (-3), 8 h a day for 4 weeks, which affects their selection for cultivation. In the first cultivar presented here, an adequate leafy vegetable supplier, the ozone load resulted in a shift of biomass to maintain the ... | ['Amino Acids', 'Carotenoids', 'Ipomoea batatas', 'Ozone', 'Plant Leaves', 'Plant Tubers', 'Starch'] | 18,593,180 | [['D12.125'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['B01.650.940.800.575.912.250.238.500.500'], ['D01.362.670.600'], ['A18.024.812'], ['A18.400.625'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pituitary adenylate cyclase-activating polypeptide: a potent activator of human intestinal ion transport. | To investigate the effects of PACAP-27 on electrolyte transport across the isolated human intestinal mucosa, changes in short-circuit current (Isc) were measured in Ussing chamber experiments. Serosally added PACAP-27 increased Isc in a concentration-dependent manner, eliciting a similar maximal effect in both the jeju... | ['Colon', 'Crohn Disease', 'Dose-Response Relationship, Drug', 'Electrolytes', 'Gastrointestinal Hormones', 'Humans', 'In Vitro Techniques', 'Intestinal Mucosa', 'Jejunum', 'Membrane Potentials', 'Natriuretic Peptides', 'Neuropeptides', 'Neurotransmitter Agents', 'Peptides', 'Pituitary Adenylate Cyclase-Activating Poly... | 8,993,454 | [['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.248'], ['D06.472.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124.684.500', 'A03.556.249.750'], ['G01.1... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensitivity to cocaine and amphetamine among mice selectively bred for differential cocaine sensitivity. | Selective breeding of mice for differences in response to a drug offers a powerful means for testing hypotheses regarding underlying mechanisms and relationships between drug-induced behaviors. Starting from a heterogeneous stock of mice, we have selectively bred lines of mice for extreme differences in their locomotor... | ['Amphetamine', 'Animals', 'Cocaine', 'Dose-Response Relationship, Drug', 'Male', 'Mice', 'Mice, Inbred Strains', 'Motor Activity', 'Species Specificity'] | 9,862,401 | [['D02.092.471.683.152.110'], ['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['F01.145.632', 'G11.427.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of extravascular extracellular space fraction in human melanoma xenografts by DCE-MRI and kinetic modeling. | Tumor aggressiveness and response to therapy are influenced by the extravascular extracellular space fraction (EESF) of the malignant tissue. The EESF may, therefore, be an important prognostic parameter for cancer patients. The aim of this study was to investigate whether gadopentetate dimeglumine (Gd-DTPA)-based dyna... | ['Analysis of Variance', 'Animals', 'Contrast Media', 'Extracellular Space', 'Female', 'Gadolinium DTPA', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Melanoma, Experimental', 'Mice', 'Mice, Inbred BALB C', 'Statistics, Nonparametric', 'Transplantation, Heterologous'] | 17,692,490 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['A10.082.500', 'A11.284.295'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['C04.557.465... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
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