Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Cancer in the Republic of Palau (Belau). | This study, funded by the National Cancer Institute, assessed cancer awareness and service needs in the Republic of Belau (Belau) in April 2003. Cancer prevention and control is a concern for Belau, and this country maintains a cancer registry to track cases and outcomes. However, assistance is needed to strengthen and... | ['Delivery of Health Care', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Medically Underserved Area', 'Needs Assessment', 'Neoplasms', 'Palau', 'Population Surveillance', 'Public Health Administration', 'Regional Health Planning', 'Registries'] | 16,281,680 | [['N04.590.374', 'N05.300'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.650.340', 'N05.300.450.520'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['C04'], ['Z01.639.760.680.717'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.4... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Smoking modifies the effect of two independent SNPs rs5063 and rs198358 of NPPA on central obesity in the Chinese Han population. | Obesity is the third most risk factors of death in the middle-income and high-income countries. Whether DNA polymorphisms in CORIN and NPPA genes were associated with obesity, and if these associations could be modified by smoking in the Chinese Han population were unknown, hence a group of 1507 participants were recru... | ['Adult', 'Asian Continental Ancestry Group', 'Atrial Natriuretic Factor', 'Body Mass Index', 'China', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Obesity, Abdominal', 'Polymorphism, Single Nucleotide', 'Risk Factors', 'Smoking'] | 30,262,711 | [['M01.060.116'], ['M01.686.508.200'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.252.474.164'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones. | We cloned a cDNA coding for a novel serine/threonine kinase, Dlk, a protein of 448 amino acids with a predicted molecular weight of 51.3 kDa. The kinase domain shows 81% amino acid sequence identity to the recently identified DAP kinase (death associated protein kinase) (Deiss et al., Genes & Dev., 9, 15-30, 1995), the... | ['Amino Acid Sequence', 'Animals', 'Apoptosis Regulatory Proteins', 'Base Sequence', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Line, Transformed', 'Cells, Cultured', 'Chromatin', 'DNA, Complementary', 'Death-Associated Protein Kinases', 'Enzyme Induction', 'Fibroblasts', 'Histones', 'Leucine Zippers', 'MAP ... | 9,840,928 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['A11.251.210.172'], ['A11.251'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A comparative study on the effect of nicotine administration and cigarette smoke inhalation on bone healing around titanium implants. | BACKGROUND: A series of isolated studies has focused on the influence of smoking on bone around titanium implants. This study proposes to investigate the impact of two conditions, i.e., nicotine administration and cigarette smoke inhalation, on the healing around implants.METHODS: Forty-five Wistar rats were used. Afte... | ['Animals', 'Cotinine', 'Implants, Experimental', 'Male', 'Niacin', 'Nicotine', 'Osseointegration', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Statistics, Nonparametric', 'Tobacco Smoke Pollution'] | 14,653,391 | [['B01.050'], ['D03.383.773.812.180'], ['E07.695.340'], ['D03.066.515.475', 'D03.383.725.547.475'], ['D03.132.760.570', 'D03.383.725.518'], ['G11.427.213.140.570', 'G16.762.150.150.570'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Treating primary liver cancer with hepatic arterial infusion of floxuridine and dexamethasone: does the addition of systemic bevacizumab improve results? | OBJECTIVES: This study investigated the efficacy and safety of adding systemic (IV) bevacizumab (Bev) to hepatic arterial infusion (HAI) with floxuridine (FUDR)/dexamethasone (Dex) in unresectable primary liver cancer.METHODS: Patients with unresectable intrahepatic cholangiocarcinoma (ICC) or hepatocellular carcinoma ... | ['Aged', 'Alkaline Phosphatase', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Combined Chemotherapy Protocols', 'Aspartate Aminotransferases', 'Bevacizumab', 'Bilirubin', 'Carcinoma, Hepatocellular', 'Cholangiocarcinoma', 'Dexamethasone', 'Disease-Free Survival', 'Early Termination of ... | 21,677,464 | [['M01.060.116.100'], ['D08.811.277.352.650.035'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D08.81... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls. | BACKGROUND: This multicenter prospective study of invasive candidiasis (IC) was carried out to determine the risk factors for, incidence of, clinical and laboratory features, treatment and outcome of IC in infants of birth weight <1250 g.METHODS: Neonates <1250 g with IC and their matched controls (2:1) were followed l... | ['Blindness', 'Canada', 'Candida', 'Candidiasis, Invasive', 'Enterocolitis, Necrotizing', 'Female', 'Humans', 'Infant', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Infant, Premature', 'Longitudinal Studies', 'Male', 'Prospective Studies', 'Risk Factors'] | 24,924,877 | [['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['Z01.107.567.176'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['C01.150.703.160.175', 'C01.150.703.492.500'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.... | ['Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cross-docking of inhibitors into CDK2 structures. 1. | Predicting protein/ligand binding affinity is one of the most challenging computational chemistry tasks. Numerous methods have been developed to address this challenge, but they all have limitations. Failure to account for protein flexibility has been a shortcoming of many methods. In this cross-docking study the data ... | ['Cyclin-Dependent Kinase 2', 'Molecular Conformation', 'Protein Kinase Inhibitors'] | 18,324,799 | [['D08.811.913.696.620.682.700.646.500.750', 'D12.644.360.250.323', 'D12.776.167.200.323', 'D12.776.476.250.323'], ['G02.111.570.820'], ['D27.505.519.389.755']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indirect Labeling of DNA for Microarrays. | As with RNA labeling protocols, the main difference between direct and indirect DNA labeling protocols is a trade-off of cost and time. Indirect labeling of DNA, described here, takes ?2 h longer than direct labeling but is hundreds of dollars cheaper. | ['Carbocyanines', 'DNA', 'Fluorescent Dyes', 'Microarray Analysis', 'Staining and Labeling'] | 31,371,472 | [['D02.455.326.397.300'], ['D13.444.308'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E05.588.570'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/â-catenin signalling. | BACKGROUND: FAT4, a cadherin-related protein, was shown to function as a tumour suppressor; however, its role in human gastric cancer remains largely unknown. Here, we investigated the role of FAT4 in gastric cancer and examined the underlying molecular mechanisms.METHODS: The expression of FAT4 was evaluated by immuno... | ['Animals', 'Cadherins', 'Epithelial-Mesenchymal Transition', 'Female', 'Gene Knockdown Techniques', 'Genes, Tumor Suppressor', 'Heterografts', 'Humans', 'Male', 'Mice', 'Middle Aged', 'Signal Transduction', 'Stomach Neoplasms', 'Tumor Suppressor Proteins', 'Wnt Proteins', 'beta Catenin'] | 26,633,557 | [['B01.050'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['G04.356.500'], ['E05.393.335.500'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['A01.941.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['M01.060.116.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
High vapor pressure deficit drives salt-stress-induced rice yield losses in India. | Flooded rice is grown across wide geographic boundaries from as far north as Manchuria and as far south as Uruguay and New South Wales, primarily because of its adaptability across diverse agronomic and climatic conditions. Salt-stress damage, a common occurrence in delta and coastal rice production zones, could be hei... | ['Agriculture', 'Climate Change', 'Geography', 'Hot Temperature', 'India', 'Oryza', 'Regression Analysis', 'Salinity', 'Seasons', 'Sodium Chloride', 'Stress, Physiological', 'Vapor Pressure'] | 25,379,616 | [['J01.040'], ['G16.500.175.374'], ['H01.277.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['Z01.252.245.393'], ['B01.650.940.800.575.912.250.822.616'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
First DNA sequences from Asian cave bear fossils reveal deep divergences and complex phylogeographic patterns. | Until recently, cave bears were believed to have only inhabited Europe. However, recent morphological evidence suggests that cave bears' geographic range extended as far east as Transbaikalia, Eastern Siberia. These Asian cave bears were morphologically distinct from European cave bears. However, how they related to Eu... | ['Animals', 'DNA, Mitochondrial', 'Europe', 'Evolution, Molecular', 'Fossils', 'Geography', 'Phylogeny', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Siberia', 'Ukraine', 'Ursidae'] | 19,226,321 | [['B01.050'], ['D13.444.308.283.225'], ['Z01.542'], ['G05.045.250', 'G16.075.250'], ['I01.076.368.584.311'], ['H01.277.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.751'], ['E05.393.760.700'], ['Z01.252.122.500.500'], ['Z01.542.248.960', 'Z01.542.931.960', 'Z01.586.950.960'], ['B01.050.150.900.649.313.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 |
Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis. | OBJECTIVE: To study the temporal expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the STR/ort mouse model of osteoarthritis, using in situ hybridization with oligonucleotide probes and specific antisera for each protein.METHODS: In situ hybridization and immunolocalization experime... | ['Animals', 'Cartilage, Articular', 'Chondrocytes', 'Collagenases', 'Fluorescent Antibody Technique', 'Gene Expression', 'In Situ Hybridization', 'Matrix Metalloproteinase 13', 'Matrix Metalloproteinase 14', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 3', 'Matrix Metalloproteinase 7', 'Matrix Metalloprotein... | 12,202,125 | [['B01.050'], ['A02.165.407.150', 'A02.835.583.192'], ['A11.329.171'], ['D08.811.277.656.300.480.205', 'D08.811.277.656.675.374.205'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['G05.297'], ['E01.370.225.500.620.670.325', 'E0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of interobserver agreement for postoperative pain and sedation assessment in cats. | OBJECTIVE To evaluate agreement between observers with different training and experience for assessment of postoperative pain and sedation in cats by use of a dynamic and interactive visual analog scale (DIVAS) and for assessment of postoperative pain in the same cats with a multidimensional composite pain scale (MCPS)... | ['Analgesia', 'Animals', 'Bupivacaine', 'Buprenorphine', 'Cats', 'Female', 'Hysterectomy', 'Observer Variation', 'Ovariectomy', 'Pain Measurement', 'Pain, Postoperative', 'Pathologists', 'Reproducibility of Results'] | 28,828,950 | [['E03.091'], ['B01.050'], ['D02.065.199.239', 'D02.092.146.113.239'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E04.950.300.399'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E04.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative studies of mononuclear Ni(II) and UO2(II) complexes having bifunctional coordinated groups: synthesis, thermal analysis, X-ray diffraction, surface morphology studies and biological evaluation. | Two Schiff base ligands derived from condensation of phthalaldehyde and o-phenylenediamine in 1:2 (L(1)) and 2:1 (L(2)) having bifunctional coordinated groups (NH(2) and CHO groups, respectively) and their metal complexes with Ni(II) and UO(2)(II) have been synthesized and characterized by elemental analysis, molar con... | ['Anti-Infective Agents', 'Bacteria', 'Electrons', 'Fungi', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Magnetics', 'Mass Spectrometry', 'Microbial Sensitivity Tests', 'Microscopy, Electron, Scanning', 'Nickel', 'Particle Size', 'Powders', 'Schiff Bases', 'Spectrophotometry, Infrared', 'Surface Properties', 'Thermog... | 22,197,356 | [['D27.505.954.122'], ['B03'], ['G01.249.335', 'G01.358.500.750'], ['B01.300'], ['D27.720.470.480'], ['E05.196.867.519'], ['H01.671.493'], ['E05.196.566'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Downregulation of core clock gene Bmal1 attenuates expression of progesterone and prostaglandin biosynthesis-related genes in rat luteinizing granulosa cells. | Ovarian circadian oscillators have been implicated in the reproductive processes of mammals. However, there are few reports regarding the detection of ovarian clock-controlled genes (CCGs). The present study was designed to unravel the mechanisms through which CCG ovarian circadian oscillators regulate fertility, prima... | ['ARNTL Transcription Factors', 'Animals', 'CLOCK Proteins', 'Cells, Cultured', 'Down-Regulation', 'Female', 'Gene Expression Regulation', 'Luteal Cells', 'Mice', 'Progesterone', 'Prostaglandins', 'Rats', 'Rats, Transgenic'] | 23,596,172 | [['D12.644.360.138.049', 'D12.776.260.103.249', 'D12.776.476.156.100', 'D12.776.930.125.249'], ['B01.050'], ['D08.811.913.050.134.415.500.049', 'D12.644.360.138.100', 'D12.776.260.103.562', 'D12.776.476.156.200', 'D12.776.930.125.562'], ['A11.251'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308'], ['A05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dual response of animals with chronic cyclosporine nephrotoxicity to an acute ischemic injury. | Normal kidneys regenerate after acute injury with little development of chronic fibrosis. However, the long-term effects of an acute injury in kidneys with established chronic toxicity induced by cyclosporine (CsA) are not entirely clear. To study the consequences of an ischemia and reperfusion (IR) injury in long-term... | ['Animals', 'Cyclosporine', 'Disease Models, Animal', 'Graft Survival', 'Kidney', 'Kidney Function Tests', 'Kidney Transplantation', 'Male', 'Rats', 'Rats, Wistar', 'Renal Circulation', 'Reperfusion Injury'] | 17,175,267 | [['B01.050'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G12.875.545.340'], ['A05.810.453'], ['E01.370.390.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of Senegalese plants used in malaria treatment: focus on Chrozophora senegalensis. | An ethnobotanical study was conducted in the Dakar area of Senegal to investigate the species used in the treatment of malaria. Seven plants are principally used: Cissampelos mucronata, Maytenus senegalensis, Terminalia macroptera, Bidens engleri, Ceratotheca sesamoides, Chrozophora senegalensis and Mitracarpus scaber.... | ['Animals', 'Chlorocebus aethiops', 'Drug Storage', 'Euphorbiaceae', 'Female', 'Malaria', 'Mice', 'Phytotherapy', 'Plant Extracts', 'Plants, Medicinal', 'Plasmodium falciparum', 'Senegal', 'Vero Cells'] | 18,063,330 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.916.350'], ['B01.650.940.800.575.912.250.859.797.438'], ['C01.610.752.530', 'C01.920.875'], ['B01.050.150.900.649.313.992.635.505.500'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['B01.650.560'], ['B01.043.075.380.611.561'], ['Z01.058.2... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Influence of alimentary habits, age and occupation on polychlorinated biphenyl levels in adipose tissue. | The levels of polychlorinated biphenyls (PCBs) in adipose tissue samples from the mammary glands of 123 women living in Cordoba (Spain) were evaluated. The influence of alimentary habits, age and previous and present occupation on the tissue levels of PCBs were also investigated. The compound found at the highest conce... | ['Adipose Tissue', 'Adult', 'Age Factors', 'Breast', 'Chromatography, Gas', 'Diet', 'Feeding Behavior', 'Female', 'Food Analysis', 'Food Contamination', 'Humans', 'Middle Aged', 'Occupations', 'Polychlorinated Biphenyls', 'Spain', 'Tissue Distribution'] | 12,453,730 | [['A10.165.114'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['A01.236'], ['E05.196.181.349'], ['G07.203.650.240'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['E05.362', 'J01.576.423.850.100'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.31... | ['Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Ureteral obstruction owing to over pressure of a normal right common iliac artery: a case report. | We report a case in which a normal right common iliac artery in a normal anatomical relationship to the right ureter at the crossing point caused partial urinary tract obstruction apparently by an over pressure effect. The ureter was attached to the promontorium periosteum following ureterolysis to relieve the obstruct... | ['Adult', 'Humans', 'Iliac Artery', 'Male', 'Pressure', 'Radiography', 'Ureteral Obstruction'] | 3,398,140 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.444'], ['G01.374.715'], ['E01.370.350.700'], ['C12.777.725.776', 'C13.351.968.725.776']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased soluble Fas-ligand in sera of bone marrow transplant recipients with acute graft-versus-host disease. | Acute graft-versus-host disease (aGVHD) is a major complication following allogeneic bone marrow transplantation (BMT). Recently, accumulating evidence indicates that the Fas/Fas ligand (FasL) system is implicated in the pathogenesis of aGVHD in murine models. We determined the serum levels of soluble FasL (sFasL) in B... | ['Adolescent', 'Adult', 'Bone Marrow Transplantation', 'Fas Ligand Protein', 'Female', 'Graft vs Host Disease', 'Hematologic Diseases', 'Humans', 'Male', 'Membrane Glycoproteins', 'Middle Aged', 'Retrospective Studies', 'Transplantation, Homologous'] | 9,827,971 | [['M01.060.057'], ['M01.060.116'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.374.750.249', 'D12.776.543.550.312', 'D23.529.374.750.249'], ['C20.452'], ['C15.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550', 'D12.776.543.550'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analyzing mitochondrial function in human peripheral blood mononuclear cells. | Mitochondrial oxidative phosphorylation (OXPHOS) is responsible for producing most of the adenosine triphosphate required by eukaryotic cells. Lymphocytes make up the majority of the peripheral blood mononuclear cells. Peripheral blood mononuclear cells are readily obtainable, providing an ideal sample to monitor syste... | ['Aged', 'Electron Transport', 'Electron Transport Chain Complex Proteins', 'Humans', 'Lymphocytes', 'Male', 'Middle Aged', 'Mitochondria', 'Oxidative Phosphorylation'] | 29,505,781 | [['M01.060.116.100'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D08.811.600.250', 'D12.776.543.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['M01.060.116.630'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G02.111.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Toxoplasmic retinochoroiditis: resolution without treatment of the perilesional satellite dark dots seen by indocyanine green angiography. | PURPOSE: Satellite dark dots (SDD) seen by indocyanine green angiography (ICGA) around the main retinochoroiditis focus are described in 75% of cases. Whether SDDs represent subclinical infectious foci or just a perilesional inflammatory reaction is not known. The purpose here was to report a case giving additional inf... | ['Acute Disease', 'Adult', 'Animals', 'Antibodies, Protozoan', 'Chorioretinitis', 'Choroid', 'Coloring Agents', 'Fluorescein Angiography', 'Follow-Up Studies', 'Fundus Oculi', 'Humans', 'Indocyanine Green', 'Male', 'Recurrence', 'Remission, Spontaneous', 'Retina', 'Toxoplasma', 'Toxoplasmosis, Ocular'] | 9,646,094 | [['C23.550.291.125'], ['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['C11.768.773.348', 'C11.941.160.478.400', 'C11.941.879.780.900.300.318'], ['A09.371.894.223'], ['D27.720.233'], ['E01.370.370.050.350', 'E01.370.380.250'], ['E05.318.372.50... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Health hazards to timber and forestry workers from the Douglas fir tussock moth. | A heavy infestation of the tussock moth caterpillar (Orgyia pseudotsugata McDonnough) in forested areas of Oregon was associated with itching of the skin and eyes, nasal discharge, cough, and, at times, respiratory difficulty, Personal interviews and inspection of forty-one occupationally exposed persons were supplemen... | ['Animals', 'Dermatitis, Occupational', 'Environmental Exposure', 'Humans', 'Hypersensitivity', 'Lepidoptera', 'Moths', 'Occupational Diseases', 'Oregon', 'Respiratory Hypersensitivity', 'Skin Tests', 'Trees'] | 143,915 | [['B01.050'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C24.270'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['B01.050.500.131.617.720.500.500.937'], ['B01.050.500.131.617.720.500.500.937.650'], ['C24'], ['Z01.107.567.875.560.550', 'Z01.107.567.875.580.550'], ['C08.674', '... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
No evidence for the differential antagonism of the initial fast and secondary slow contractile responses of the rat portal vein to phenylephrine, 5-hydroxytryptamine or methacholine. | 1. The present study was to ascertain whether drugs cause differential antagonism of the initial fast and secondary slow contractile responses to phenylephrine, 5-HT and methacholine of the rat portal vein. 2. Cocaine (5 x 10(-6) M) had no effect on the responses to methacholine. Cocaine potentiated the initial fast bu... | ['Adrenergic alpha-Antagonists', 'Animals', 'Cocaine', 'In Vitro Techniques', 'Male', 'Methacholine Chloride', 'Methacholine Compounds', 'Parasympatholytics', 'Phenylephrine', 'Portal Vein', 'Rats', 'Rats, Inbred Strains', 'Serotonin', 'Serotonin Antagonists', 'Vasoconstriction'] | 2,902,098 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['E05.481'], ['D02.092.877.883.555.500', 'D02.675.276.534.500'], ['D02.092.877.883.555', 'D02.675.276.534'], ['D27.505.696.663.050.650'], ['D02.033.100.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of chronic obstructive pulmonary disease and frailty on long-term outcomes and quality of life after transcatheter aortic valve implantation. | BACKGROUND: Association between chronic obstructive pulmonary disease (COPD) and long-term mortality as well as the quality of life (QoL) in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) is still unclear.AIM: We sought to evaluate the impact of COPD on mortality and... | ['Aged', 'Aged, 80 and over', 'Aortic Valve', 'Aortic Valve Stenosis', 'Female', 'Frailty', 'Humans', 'Male', 'Pulmonary Disease, Chronic Obstructive', 'Quality of Life', 'Risk Factors', 'Stroke', 'Time Factors', 'Transcatheter Aortic Valve Replacement', 'Treatment Outcome'] | 29,185,204 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['C23.550.359'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495.389'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.36... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Multimerization is required for antigen binding activity of an engineered IgM/IgG chimeric antibody recognizing a skin-related antigen. | Monoclonal antibodies offer great tools for research. We encountered a potentially useful mouse IgM monoclonal antibody whose antigen is expressed in normal skin but lost in human skin cancer. Because IgM is difficult to work with and the antigen was unknown, we decided to convert the IgM (µ) to IgG (ã) version. After ... | ['Animals', 'Antibodies, Monoclonal', 'Antigens', 'Fluorescent Antibody Technique', 'Humans', 'Immunoglobulin G', 'Immunoglobulin Heavy Chains', 'Immunoglobulin M', 'Immunoglobulin Variable Region', 'Mice', 'Mutation', 'Protein Binding', 'Protein Multimerization', 'Recombinant Fusion Proteins', 'Skin'] | 28,811,604 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of ASIC2 in ciliated cells and stereociliated cells. | Acid-sensing ion channel 2 (ASIC2) plays a role as a mechanorecptor and acid receptor in the peripheral and central nervous systems. However, several recent studies have suggested that ASIC2 is expressed in several organs, in addition to the nervous system. We have examined the expression and distribution of ASIC2 in r... | ['Acid Sensing Ion Channels', 'Amino Acid Sequence', 'Animals', 'Cilia', 'Degenerin Sodium Channels', 'Epididymis', 'Epithelial Sodium Channels', 'Female', 'Hair Cells, Ampulla', 'Hair Cells, Auditory', 'Male', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Oviducts', 'Rats', 'Sequence Alignment', 'Sequence Homol... | 18,560,896 | [['D12.776.157.530.400.875.050', 'D12.776.543.550.450.875.050', 'D12.776.543.585.400.875.050', 'D12.776.631.024'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.284.180.165'], ['D12.776.157.530.400.875.100', 'D12.776.543.550.450.875.100', 'D12.776.543.585.400.875.100'], ['A05.360.444.371'], ['D12.776.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Private health insurance and medical care utilization: evidence from the Medicare population. | This paper examines the impact of supplemental health insurance policy ownership on the use of health care services by the elderly. It employs a data base consisting of Medicare claims data from over 2,000 beneficiaries in six states, actual copies of their supplemental insurance policies, and detailed survey informati... | ['Aged', 'Health Status', 'Hospitals', 'Humans', 'Insurance Selection Bias', 'Insurance, Health', 'Insurance, Medigap', 'Medicare Part A', 'Medicare Part B', 'Office Visits', 'Ownership', 'United States'] | 1,833,338 | [['M01.060.116.100'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.585'], ['N03.219.521.576.343'], ['N03.219.521.576.343.539'], ['N03.219.521.346.506.564.663.500', 'N03.219.521.576.343.840.725', 'N03.706.615.698'], ['N03.219.5... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Chronic constipation diagnosis and treatment evaluation: the "CHRO.CO.DI.T.E." study. | BACKGROUND: According to Rome criteria, chronic constipation (CC) includes functional constipation (FC) and irritable bowel syndrome with constipation (IBS-C). Some patients do not meet these criteria (No Rome Constipation, NRC). The aim of the study was is to evaluate the various clinical presentation and management o... | ['Adult', 'Aged', 'Chronic Disease', 'Colonoscopy', 'Constipation', 'Defecography', 'Digital Rectal Examination', 'Female', 'Humans', 'Irritable Bowel Syndrome', 'Italy', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Symptom Assessment'] | 28,088,179 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.500'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C23.888.821.150'], ['E01.370.350.700.715.250'], ['E01.370.600.600.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.158.272.608'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Role of videomediastinoscopy in diagnostic procedures of pathological conditions in the mediastinum]. | Due to recent advances in videotechnology and a worldwide comback of invasive staging methods of the lung cancer, mediastinoscopy has been revived. In the Surgical Clinic of the Faculty Hospital in Plzen, the authors carried out 54 videomagnetoscopic examinations of 53 patients aged 58.1 years on average, in total, dur... | ['Adult', 'Aged', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Mediastinal Neoplasms', 'Mediastinoscopy', 'Middle Aged', 'Video Recording'] | 15,552,017 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.588.894.479', 'C08.846.187.580'], ['E01.370.388.250.560', 'E04.502.250.560', 'E04.928.490'], ['M01.060.116.630'], ['L01.280.960']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Proteomic analysis of changes in protein expression in liver mitochondria in apoE knockout mice. | The involvement of both apolipoprotein E (apoE) and mitochondria in lipid metabolism is widely recognized, however there is surprisingly scarce data about the putative mitochondrial action(s) of this protein. The aim of the study was to screen the alterations in liver mitochondrial proteome caused by apoE deficiency. W... | ['Animals', 'Apolipoproteins E', 'Electrophoresis, Gel, Two-Dimensional', 'Female', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mitochondria, Liver', 'Proteome', 'Proteomics'] | 21,406,262 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['E05.196.401.250', 'E05.301.300.230'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Dinosaur girls, candy girls, and Trinity: voices of Taiwanese club drug users. | Research among Asian users of methylenedioxy methamphetamine (MDMA), also known as Ecstasy, is rare. To evaluate the feasibility of a study on the abuse of and dependence on Ecstasy, two focus groups of users (n= 12) and health professionals (n=7) were conducted in Taiwan. Major results included blatant human testing w... | ['Adolescent', 'Adult', 'Data Collection', 'Female', 'Focus Groups', 'Hallucinogens', 'Health Personnel', 'Humans', 'Illicit Drugs', 'Ketamine', 'Male', 'Marijuana Abuse', 'N-Methyl-3,4-methylenedioxyamphetamine', 'Substance-Related Disorders', 'Taiwan', 'Young Adult'] | 19,042,808 | [['M01.060.057'], ['M01.060.116'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['D27.505.696.388', 'D27.505.954.427.700.372'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['D02.455.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Validation of continuous radionuclide left ventricular functioning monitoring in detecting silent myocardial ischemia during balloon angioplasty of the left anterior descending coronary artery. | Silent myocardial ischemia has been inferred from transient ST-segment depression during continuous electrocardiographic monitoring. Recently, continuous ambulatory monitoring of left ventricular (LV) function using a radionuclide technique (VEST) has demonstrated episodes of significant silent LV dysfunction in the ab... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Disease', 'Electrocardiography, Ambulatory', 'Humans', 'Male', 'Middle Aged', 'Radionuclide Ventriculography', 'Stroke Volume', 'Ventricular Function, Left'] | 2,042,565 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Responses of human skin in organ culture and human skin fibroblasts to a gadolinium-based MRI contrast agent: comparison of skin from patients with end-stage renal disease and skin from healthy subjects. | OBJECTIVE: Nephrogenic systemic fibrosis is a clinical syndrome occurring in a small subset of patients with end-stage renal disease (ESRD). Exposure to certain of the gadolinium-based contrast agents during magnetic resonance imaging appears to be a trigger. The pathogenesis of the disease is largely unknown. The pres... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Contrast Media', 'Female', 'Fibroblasts', 'Gadolinium', 'Humans', 'Hyaluronic Acid', 'Kidney Failure, Chronic', 'Magnetic Resonance Imaging', 'Male', 'Matrix Metalloproteinase 1', 'Matrix Metalloproteinase Inhibitors', 'Middle Aged', 'Nephrogenic Fibrosing... | 20,661,146 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D27.505.259.500', 'D27.720.259'], ['A11.329.228'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['C12.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytochrome P-450-dependent monooxygenases in olfactory epithelium of dogs: possible role in tumorigenicity. | The respiratory tract epithelium of dogs, from the nose to the lungs, was examined for cytochrome P-450 and associated biotransformation activities. In the ethmoturbinates, where olfactory epithelium is located, the amount of cytochrome P-450 was comparable to that in the liver, when measured on the basis of activity p... | ['Animals', 'Biotransformation', 'Cytochrome P-450 Enzyme System', 'Dogs', 'Liver', 'Lung', 'Microsomes', 'Nasal Mucosa', 'Neoplasms', 'Oxygenases'] | 7,063,870 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['B01.050.150.900.649.313.750.250.216.200'], ['A03.620'], ['A04.411'], ['A11.284.835.540'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['C04'], ['D08.811.682.690']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes. | Mammalian SWI/SNF chromatin remodeling complexes are involved in critical aspects of cellular growth and genomic stability. Each complex contains one of two highly homologous ATPases, BRG1 and BRM, yet little is known about their specialized functions. We show that BRG1and BRM associate with different promoters during ... | ['Adenosine Triphosphatases', 'Animals', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'Chromatin', 'Chromosomal Proteins, Non-Histone', 'DNA', 'DNA Helicases', 'Humans', 'In Vitro Techniques', 'Mice', 'Nuclear Proteins', 'Promoter Regions, Genetic', 'Protein Binding', 'Protein Structure, Tertiary', 'Recombinan... | 12,620,226 | [['D08.811.277.040.025'], ['B01.050'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.660.235', 'D12.776.664.235'], ['D13.444.308'], ['D08.811.277.040.025.159', 'D08.811.399.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delivering cognitive-behavior therapy for panic disorder with agoraphobia in videoconference. | Delivering psychotherapy by videoconference could significantly increase the accessibility of empirically validated treatments. The aim of this study was to compare the effectiveness of cognitive-behavior therapy (CBT) for panic disorder with agoraphobia (PDA) when the therapy is delivered either face-to-face or by vid... | ['Adult', 'Agoraphobia', 'Cognitive Behavioral Therapy', 'Computer Terminals', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mental Health Services', 'Middle Aged', 'Ontario', 'Panic Disorder', 'Random Allocation', 'Remote Consultation', 'Rural Health Services', 'Surveys and Questionnaires'] | 15,104,911 | [['M01.060.116'], ['F03.080.100'], ['F04.754.137.350'], ['L01.224.230.260.115.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.408', 'N02.421.461'], ['M01.060.116.630'], ['Z01.107.567.176.639'], ['F03.080.700'], ['E0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A species checklist of the millipedes (Myriapoda, Diplopoda) of India. | At present, the millipede fauna of India comprises over 270 nominate species or subspecies in at least 90 genera, 25 families and 11 orders. As complete a catalogue as possible is compiled of all species or subspecies of Diplopoda formally reported from India, some of which remain dubious. Additionally, a checklist is ... | ['Animal Distribution', 'Animals', 'Arthropods', 'India', 'Species Specificity'] | 27,395,645 | [['F01.145.113.069', 'G16.049'], ['B01.050'], ['B01.050.500.131'], ['Z01.252.245.393'], ['G16.824']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
General cognitive ability in children with reading comprehension difficulties. | BACKGROUND: Children with specific reading comprehension difficulties read accurately and fluently but are poor at understanding what they read.AIMS: This study investigated cognitive ability in children with poor reading comprehension with a view to determining the relationship between general cognitive ability and sp... | ['Child', 'Cognition', 'Comprehension', 'Humans', 'Learning Disabilities', 'Male', 'Reading'] | 12,495,566 | [['M01.060.406'], ['F02.463.188'], ['F02.463.188.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['L01.559.423.557']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Tocilizumab in rheumatoid arthritis: a meta-analysis of efficacy and selected clinical conundrums. | INTRODUCTION: Tocilizumab (TCZ) is a biological agent used for the treatment of moderate to severe rheumatoid arthritis (RA). In the present systematic literature review and meta-analysis, we provide an update on the efficacy and safety of TCZ and our clinical comments for the treatment of RA.METHODS: We searched PubMe... | ['Antibodies, Monoclonal, Humanized', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Humans', 'Treatment Outcome'] | 24,262,929 | [['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Effect of 10-15% carbamide peroxide on enamel fluoride concentration in vital bleached teeth]. | The objective of the study was to evaluate the concentration of fluoride in human enamel before and after bleaching using 10-15% carbamide peroxide and after application of the fluoride varnish. Microsamples of enamel were collected using acid biopsy and the concentration of fluoride in the superficial and underlying l... | ['Biopsy', 'Carbamide Peroxide', 'Dental Enamel', 'Drug Combinations', 'Humans', 'Peroxides', 'Sodium Fluoride', 'Tooth Bleaching', 'Urea'] | 16,892,581 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D01.248.497.158.685.750.318', 'D01.339.431.374.318', 'D01.650.550.750.300', 'D02.065.950.278', 'D02.389.338.154'], ['A14.549.167.900.255'], ['D26.310'], ['B01.050.150.900.649... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evolution of chromosome organization driven by selection for reduced gene expression noise. | The distribution of genes on eukaryotic chromosomes is nonrandom, but the reasons behind this are not well understood. The commonly observed clustering of essential genes is a case in point. Here we model and test a new hypothesis. Essential proteins are unusual in that random fluctuations in abundance (noise) can be h... | ['Animals', 'Chromosomes', 'Eukaryotic Cells', 'Evolution, Molecular', 'Gene Expression', 'Gene Order', 'Genome', 'Models, Genetic', 'Multigene Family', 'Yeasts'] | 17,660,811 | [['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['A11.450'], ['G05.045.250', 'G16.075.250'], ['G05.297'], ['G05.340'], ['G05.360.340'], ['E05.599.395.397'], ['G05.360.340.024.340.645'], ['B01.300.930']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Post-DSAEK optical changes: a comprehensive prospective analysis on the role of ocular wavefront aberrations, haze, and corneal thickness. | PURPOSE: The aim was to assess the visual impact of ocular wavefront aberrations, corneal thickness, and corneal light scatter prospectively after performing a Descemet stripping automated endothelial keratoplasty (DSAEK) in humans.METHODS: Data were obtained prospectively from 20 eyes preoperatively and at 1, 3, 6, an... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Corneal Topography', 'Corneal Wavefront Aberration', 'Descemet Stripping Endothelial Keratoplasty', 'Female', 'Glare', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Pseudophakia', 'Tomography, Optical Coherence', 'Visual Acuity'] | 24,162,748 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.380.150'], ['C11.204.431', 'C11.744.345'], ['E02.095.147.725.262', 'E04.540.825.374.112', 'E04.936.580.262'], ['G01.590.540.333', 'G14.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Value of cross-sectional area of median nerve by MRI in carpal tunnel syndrome. | BACKGROUND: Carpal tunnel syndrome is diagnosed based on history, physical examination, and nerve conduction testing; however, there are no clear criteria for the diagnosis of carpal tunnel syndrome. Recently, studies have aimed to diagnose carpal tunnel syndrome through ultrasound or MRI. The purpose of this study was... | ['Aged', 'Carpal Tunnel Syndrome', 'Female', 'Hamate Bone', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Median Nerve', 'Middle Aged', 'Neural Conduction', 'Pain', 'Physical Examination', 'Retrospective Studies'] | 31,473,048 | [['M01.060.116.100'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['A02.835.232.087.319.150.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.800.800.720.050.500'], ['M01.060.116.630'], ['G07.265.753', 'G11.561.601'], ['C23.888.592.612', 'F02.830.816.444',... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Semiautomated resolution of overlapping stutter patterns in genomic microsatellite analysis. | Microsatellites are polymorphic, short nucleotide repeating units scattered more or less randomly throughout the genome. They are readily detectable by polymerase chain reaction (PCR) and often used as genomic markers. One problem in the analysis of microsatellite data is the appearance of secondary bands during PCR th... | ['Algorithms', 'Alleles', 'Cell Line', 'DNA', 'Humans', 'Loss of Heterozygosity', 'Microsatellite Repeats', 'Models, Theoretical', 'Polymerase Chain Reaction'] | 9,300,082 | [['G17.035', 'L01.224.050'], ['G05.360.340.024.340.030'], ['A11.251.210'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.029.530'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['E05.599'], ['E05.393.620.500']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
HIV prevalence and risk in long-distance truck drivers in South Africa: a national cross-sectional survey. | We estimated the prevalence of HIV and assessed correlates of HIV infection in long-distance truck drivers in South Africa. Between October 2003 and July 2004, 1900 long-distance truck drivers aged ?18 years consented to interview and for testing for HIV. Participants were selected from a 10% stratified random sample o... | ['Adult', 'Automobile Driving', 'Condoms', 'Cross-Sectional Studies', 'Female', 'HIV Infections', 'Humans', 'Interviews as Topic', 'Logistic Models', 'Male', 'Middle Aged', 'Motor Vehicles', 'Multivariate Analysis', 'Occupations', 'Prevalence', 'Risk Factors', 'Risk-Taking', 'Sexual Behavior', 'Sexual Partners', 'South... | 24,352,131 | [['M01.060.116'], ['I03.125'], ['E07.190.270.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.42... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Geogr... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Staining patterns of keratins in the human urinary tract. | The keratins, members of the intermediate filament family, are characteristically expressed in epithelial cells. In the various types of epithelia, the keratin expression pattern is characterized by cell-type specific combinations of the keratin isotypes with a plain pattern in monolayered (simple) epithelia and more c... | ['Adult', 'Fluorescent Antibody Technique', 'Humans', 'Keratins', 'Microscopy, Electron, Transmission', 'Staining and Labeling', 'Urinary Tract', 'Urothelium'] | 19,760,592 | [['M01.060.116'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['E01.370.350.515.402.580', 'E05.595.402.580'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Full sternotomy through a minimally invasive incision: a cardiac surgeon's true comfort zone. | Increasing attention is being paid by cardiac surgeons to performing cardiac surgical procedures through less invasive approaches, including the use of limited incisions. A limited incisional approach is described that achieves full sternotomy, allows the use of standard operative instruments and techniques, permits ra... | ['Cardiac Surgical Procedures', 'Humans', 'Minimally Invasive Surgical Procedures', 'Sternum'] | 9,800,857 | [['E04.100.376', 'E04.928.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.502'], ['A02.835.232.570.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Construction of a recombinant Lactobacillus acidophilus expressing high levels of Helicobacter pylori adhesin Hp0410]. | OBJECTIVE: To construct a recombinant Lactobacillus acidophilus that expresses high levels of Helicobacter pylori (Hp) adhesin Hp0410.METHODS: The gene fragment encoding Hp0410 was amplified by PCR from the DNA of H. pylori NCTC11639 strain and cloned into the shuttle plasmid pMG36e to construct pMG36e-Hp0410, which wa... | ['Adhesins, Bacterial', 'Bacterial Vaccines', 'Helicobacter Infections', 'Humans', 'Lactobacillus acidophilus', 'Plasmids', 'Recombinant Proteins', 'Vaccines, Attenuated'] | 20,159,678 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['D20.215.894.135'], ['C01.150.252.400.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.100', 'B03.510.460.400.410.475.475.100', 'B03.510.550.450.475.100'], ['G05.360.600'], ['D12.776.828'], ['D20.215.894.811']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adenovirus vector expressing keratinocyte growth factor using CAG promoter impairs pulmonary function of mice with elastase-induced emphysema. | Pulmonary emphysema impairs quality of life and increases mortality. It has previously been shown that administration of adenovirus vector expressing murine keratinocyte growth factor (KGF) before elastase instillation prevents pulmonary emphysema in mice. We therefore hypothesized that therapeutic administration of KG... | ['Adenoviridae', 'Alveolar Epithelial Cells', 'Animals', 'Bleomycin', 'DNA, Viral', 'Disease Models, Animal', 'Emphysema', 'Fibroblast Growth Factor 7', 'Genetic Therapy', 'Genetic Vectors', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Pancreatic Elastase', 'Promoter Regions, Genetic', 'Pulmonary Fibrosis', 'Pulmonary Surfa... | 28,543,309 | [['B04.280.030'], ['A04.411.715.100', 'A11.436.081'], ['B01.050'], ['D09.400.420.110', 'D12.644.233.110'], ['D13.444.308.568'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.325'], ['D12.644.276.624.170', 'D12.776.467.624.170', 'D23.529.624.170'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nurses' Perceptions of Implementing Fall Prevention Interventions to Mitigate Patient-Specific Fall Risk Factors. | Evidence-based (EB) fall prevention interventions to mitigate patient-specific fall risk factors are readily available but not routinely used in practice. Few studies have examined nurses' perceptions about both the use of these EB interventions and implementation strategies designed to promote their adoption. This art... | ['Accidental Falls', 'Attitude of Health Personnel', 'Evidence-Based Practice', 'Female', 'Humans', 'Male', 'Nurses', 'Patient-Centered Care', 'Qualitative Research', 'Risk Factors', 'Surveys and Questionnaires'] | 27,106,881 | [['N06.850.135.122'], ['F01.100.050', 'N05.300.100'], ['H02.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650', 'N02.360.650'], ['N04.590.233.727.407'], ['H01.770.644.241.850'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Venous thromboembolism: pharmacological and nonpharmacological interventions. | The formation of blood clots is a significant threat to individuals with limited mobility, whether in the hospital or recovering in an outpatient setting. Prevention of deep vein thrombosis and pulmonary embolism has been found to be cost-effective when compared with treating an existing thrombosis. Despite these posit... | ['Anticoagulants', 'Factor Xa Inhibitors', 'Heparin, Low-Molecular-Weight', 'Humans', 'Intermittent Pneumatic Compression Devices', 'Practice Guidelines as Topic', 'Stockings, Compression', 'Vena Cava Filters', 'Venous Thromboembolism', 'Vitamin K'] | 19,858,963 | [['D27.505.954.502.119'], ['D27.505.519.389.745.800.449.500', 'D27.505.954.502.119.500.500'], ['D09.698.373.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.515'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E07.101.400.500'], ['E07.695.207.500'], ['C14.907.355.590.700'], ['D02.455.426.559.847.638.72... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Clinical characteristics and mechanism of liver injury in patients with severe acute respiratory syndrome]. | OBJECTIVES: To summarize the clinical features of liver injury in patients with severe acute respiratory syndrome (SARS), providing information for further mechanism and clinical study.METHODS: The clinical and some laboratory data of 154 patients suffered from SARS were collected and analyzed, who were admitted to the... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Alanine Transaminase', 'Female', 'Humans', 'Interleukin-1', 'Interleukin-10', 'Interleukin-6', 'Liver', 'Liver Diseases', 'Liver Function Tests', 'Male', 'Middle Aged', 'Severe Acute Respiratory Syndrome', 'Systemic Inflammatory Response Syndrome'] | 12,939,186 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.913.477.700.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parents' decision making and access to preventive healthcare for young children: applying Andersen's Model. | BACKGROUND AND OBJECTIVE: Implementing preventive health care for young children provides the best chance of improving health and changing a child's life course. In Australia, despite government support for preventive health care, uptake of preventive services for young children is low. Using Andersen's behavioural mod... | ['Australia', 'Child, Preschool', 'Decision Making', 'Female', 'Health Services Accessibility', 'Humans', 'Male', 'Parenting', 'Parents', 'Preventive Health Services', 'Professional-Family Relations'] | 23,796,071 | [['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406.448'], ['F02.463.785.373'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.310'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['N02.421.726'], ['F01.829.401.550']] | ['Geographicals [Z]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Influence of 5'-terminal m7G and 2'--O-methylated residues on messenger ribonucleic acid binding to ribosomes. | Removal of 80% of the 5'-terminal 7-methyl-guanosine (m7G) from methylated reovirus mRNA by beta elimination results in a concomitant loss of the ability to bind to wheat germ ribosomes. The mRNA molecules that retain the m7G account for most of the residual binding. Removal of the m7G from all molecules in preparation... | ['Animals', 'Cytosine Nucleotides', 'Guanine Nucleotides', 'Kinetics', 'Methylation', 'Plants', 'RNA, Messenger', 'RNA, Viral', 'Rabbits', 'Reoviridae', 'Reticulocytes', 'Ribosomes', 'Triticum'] | 1,009,086 | [['B01.050'], ['D03.383.742.686.246', 'D13.695.740.246', 'D13.695.827.232'], ['D03.633.100.759.646.454', 'D13.695.667.454', 'D13.695.827.426'], ['G01.374.661', 'G02.111.490'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['B01.650'], ['D13.444.735.544'], ['D13.444.735.828'], ['B01.050.150.900.649.313.968.700'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coverage error of three conceptually different shade guide systems to vital unrestored dentition. | STATEMENT OF PROBLEM: It remains unclear which shade guide system is most representative of the shades found in the human dentition.PURPOSE: The purpose of this study was to determine and to compare the coverage errors (CEs) of 3 different shades in a selected population.MATERIAL AND METHODS: The coverage errors of the... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Color', 'Colorimetry', 'Cuspid', 'Humans', 'Incisor', 'Maxilla', 'Middle Aged', 'Prosthesis Coloring', 'Reference Standards'] | 17,854,618 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.590.540.199'], ['E05.196.922.250'], ['A14.549.167.860.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.86... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Choroidal vascular changes in age-related macular degeneration. | PURPOSE: To assess the choroidal vascular changes using choroidal vascularity index (CVI) in patients with age-related macular degeneration (AMD) compared to controls.METHODS: Enhanced depth imaging (EDI) optical coherence tomography (OCT) scans of 64 patients with unilateral or bilateral AMD were obtained. Images with... | ['Choroid', 'Disease Progression', 'Female', 'Fluorescein Angiography', 'Follow-Up Studies', 'Fundus Oculi', 'Humans', 'Male', 'Middle Aged', 'Retinal Vessels', 'Retrospective Studies', 'Tomography, Optical Coherence', 'Visual Acuity', 'Wet Macular Degeneration'] | 28,391,615 | [['A09.371.894.223'], ['C23.550.291.656'], ['E01.370.370.050.350', 'E01.370.380.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.015.611'], ['E05.318.372.500.500.500', 'E05.3... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct detection of methicillin resistance in Staphylococcus aureus in blood culture broth by use of a penicillin binding protein 2a latex agglutination test. | We studied the utility of performing a penicillin binding protein 2a latex agglutination (PBP-LA) assay directly on Bactec blood culture broth samples containing Staphylococcus aureus to rapidly detect methicillin resistance. The sensitivity, specificity, positive predictive value, and negative predictive value of this... | ['Bacterial Proteins', 'Bacteriological Techniques', 'Blood', 'Humans', 'Latex Fixation Tests', 'Methicillin-Resistant Staphylococcus aureus', 'Penicillin-Binding Proteins', 'Predictive Value of Tests', 'Sensitivity and Specificity'] | 20,129,965 | [['D12.776.097'], ['E01.370.225.875.150', 'E05.200.875.150'], ['A12.207.152', 'A15.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.050.450', 'E05.200.812.735.050.450', 'E05.478.594.760.050.450'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750.750.100.500', 'B03.510.100.750.750.100.50... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intestinal flora of the medicinal leech Hirudinaria manillensis. | Medicinal leeches are widely used to treat venous congestion in microvascular surgery. Aeromonas hydrophila infection, following application of the leech species Hirudo medicinalis, is a recognized complication. Administration of antibiotics directed at Aeromonas has been successful in minimizing complications of infec... | ['Aeromonas', 'Animals', 'Cephalosporins', 'Gram-Negative Bacterial Infections', 'Humans', 'Intestines', 'Leeches'] | 8,182,569 | [['B03.440.450.019.025'], ['B01.050'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['C01.150.252.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['B01.050.500.091.426']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Home hemodialysis review in Iowa: 1970--1977. | One hundred fifty-two patients were accepted for home hemodialysis training from 1970 to 1976. Duration of training varied from 4 to 22 weeks. The primary reason for discontinuing home dialysis was patient and assistant psychological adjustment problems. Patient medical and technical problems were not related to the di... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Aged', 'Cardiovascular Diseases', 'Child', 'Female', 'Hemodialysis, Home', 'Humans', 'Iowa', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies'] | 363,085 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14'], ['M01.060.406'], ['E02.870.300.300', 'E02.912.800.300', 'N02.421.143.524.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.510.370'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Active fiber composites for the generation of Lamb waves. | Active fiber composites (AFC) are thin and conformable transducer elements with orthotropic material properties, since they are made of one layer of piezoelectric ceramic fibers. They are suitable for applications in structural health monitoring systems (SHM) with acoustic non-destructive testing methods (NDT). In the ... | ['Ceramics', 'Computer Simulation', 'Computer-Aided Design', 'Equipment Design', 'Equipment Failure Analysis', 'Manufactured Materials', 'Models, Chemical', 'Scattering, Radiation', 'Transducers', 'Ultrasonics'] | 18,621,408 | [['J01.637.153'], ['L01.224.160'], ['L01.224.108.150', 'L01.296.110.150'], ['E05.320'], ['E05.325.192'], ['J01.637'], ['E05.599.495'], ['E05.196.822', 'G01.867'], ['E07.305.812'], ['H01.671.031.849']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
The effect of skin fatty acids on Staphylococcus aureus. | Staphylococcus aureus is a commensal of the human nose and skin. Human skin fatty acids, in particular cis-6-hexadecenoic acid (C-6-H), have high antistaphylococcal activity and can inhibit virulence determinant production. Here, we show that sub-MIC levels of C-6-H result in induction of increased resistance. The mech... | ['Bacterial Proteins', 'Cell Wall', 'Drug Resistance, Bacterial', 'Gene Expression Regulation, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Palmitic Acids', 'Proteome', 'Skin', 'Staphylococcus aureus', 'Virulence Factors'] | 25,325,933 | [['D12.776.097'], ['A11.284.183'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['G05.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D10.251.694'], ['D12.776.817'], ['A17.815'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.7... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Orbital giant cell angiofibroma recurring as a solitary fibrous tumor. | Giant cell angiofibroma has recently been hypothesized to be a clinicopathologic variant of solitary fibrous tumor. The authors report a case of an orbital giant cell angiofibroma that recurred as a solitary fibrous tumor 4 years later. The report strongly supports the hypothesis that giant cell angiofibroma and solita... | ['Adult', 'Angiofibroma', 'Biomarkers, Tumor', 'Female', 'Giant Cells', 'Humans', 'Neoplasm Proteins', 'Neoplasm Recurrence, Local', 'Orbital Neoplasms', 'Solitary Fibrous Tumors'] | 18,645,449 | [['M01.060.116'], ['C04.557.645.100'], ['D23.101.140'], ['A11.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.624'], ['C04.697.655', 'C23.550.727.655'], ['C04.588.149.721.656', 'C04.588.364.659', 'C05.116.231.754.659', 'C11.319.457', 'C11.675.659'], ['C04.557.450.565.590.797']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relation of intramuscular pressure to the force output and myoelectric signal of skeletal muscle. | The force output of the biceps brachii muscle during static isometric contractions was studied in 26 arms of 23 subjects in relation to the simultaneously recorded level of the electromyogram (EMG) and the intra-muscular pressure (IMP). The EMG was picked up with wire electrodes and the IMP recorded through wick cathet... | ['Adult', 'Arm', 'Biomechanical Phenomena', 'Electromyography', 'Humans', 'Isometric Contraction', 'Male', 'Middle Aged', 'Models, Biological', 'Muscle Contraction', 'Muscles', 'Posture', 'Pressure'] | 6,491,819 | [['M01.060.116'], ['A01.378.800.075'], ['G01.154.090', 'G01.374.089'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['M01.060.116.630'], ['E05.599.395'], ['G11.427.494'], ['A02.633', 'A10.690'], ['G11.427.695'], ['G01.374.715']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Socioeconomic variation in admission for diseases of female genital system and breast in a national cohort aged 15-43. | OBJECTIVE: To investigate socioeconomic variation among young women in the risk of hospital admission for diseases (including neoplasms) of the female genital system and breast and for the common surgical procedures of dilatation and curettage and hysterectomy.DESIGN: Large nationally representative cohort study with i... | ['Adolescent', 'Adult', 'Breast Diseases', 'Cohort Studies', 'Dilatation and Curettage', 'Educational Status', 'Female', 'Genital Diseases, Female', 'Health Services Needs and Demand', 'Humans', 'Hysterectomy', 'Patient Admission', 'Risk', 'Social Class', 'Socioeconomic Factors', 'United Kingdom'] | 7,580,490 | [['M01.060.057'], ['M01.060.116'], ['C17.800.090'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.157.310', 'E04.950.300.299'], ['N01.824.196'], ['C13.351.500'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E02.760.400... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Incorporating correlation for multivariate failure time data when cluster size is large. | We propose a new estimation method for multivariate failure time data using the quadratic inference function (QIF) approach. The proposed method efficiently incorporates within-cluster correlations. Therefore, it is more efficient than those that ignore within-cluster correlation. Furthermore, the proposed method is ea... | ['Cluster Analysis', 'Computer Simulation', 'Data Interpretation, Statistical', 'Humans', 'Liver Cirrhosis, Biliary', 'Monte Carlo Method', 'Time Factors'] | 19,673,860 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.130.120.135.250.250', 'C06.552.150.250', 'C06.552.630.400', 'C23.550.35... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Rapid detection of mcr-1 by recombinase polymerase amplification. | PURPOSE: The plasmid-mediated mcr-1 gene conferring colistin resistance has a strong ability to spread. The objective of this study was to establish a rapid and sensitive recombinase polymerase amplification (RPA) method for plasmid-mediated polymyxin-resistant gene mcr-1 detection.METHODS: Using the reported sequence ... | ['Bacteria', 'Bacterial Proteins', 'DNA, Bacterial', 'Drug Resistance, Bacterial', 'Nucleic Acid Amplification Techniques', 'Polymyxins'] | 30,355,422 | [['B03'], ['D12.776.097'], ['D13.444.308.212'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['E05.393.620'], ['D04.345.566.780', 'D10.477.750', 'D12.644.050.600', 'D12.644.641.780', 'D12.776.543.695.054.600']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elderly patients with two episodes of fragility hip fractures form a special subgroup. | PURPOSE: To identify the demographic features of patients aged 65 years or older admitted with 2 episodes of fragility hip fractures.METHODS: From July 2003 to December 2004 inclusive, 50 consecutive elderly patients underwent surgery for a second episode of hip fracture. Patients in a very poor physical condition and ... | ['Aged', 'Aged, 80 and over', 'Female', 'Fractures, Spontaneous', 'Hip Fractures', 'Humans', 'Male', 'Middle Aged'] | 17,200,523 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.404.374'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple factors regulating the expression of human thromboxane synthase gene. | Characterization of the 5.5 kb promoter of human thromboxane synthase (TS) gene revealed a proximal positive regulatory sequence (PPRS, -90 to -25 bp) and several distal repressive elements. The maximal promoter activity was found to reside within the first 285 bp, approximately 75% of which was contributed by the PPRS... | ['Animals', 'CHO Cells', 'Carcinoma, Hepatocellular', 'Cell Line', 'Cell Nucleus', 'Cricetinae', 'DNA Methylation', 'Gene Expression Regulation, Enzymologic', 'Genes, Reporter', 'HL-60 Cells', 'Humans', 'Liver Neoplasms', 'Luciferases', 'Mice', 'Rats', 'Recombinant Proteins', 'Regulatory Sequences, Nucleic Acid', 'Rest... | 8,920,981 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.992.635.075.250'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Scorpio single radius total knee arthroplasty. A minimal five-year follow-up multicentric study. | PURPOSE: Our goal was to evaluate the five-year follow-up results of the Scorpio single radius total knee arthroplasty.METHOD: We performed a retrospective study based upon a multicentre database to evaluate the minimum five-year follow-up clinical and radiological results of 747 patients (831 knees) who underwent prim... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'Databases, Factual', 'Female', 'Humans', 'Joint Diseases', 'Knee Joint', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Range of Motion, Articular', 'Reoperation', 'Retrospective Studies', 'Treatment Ou... | 21,365,193 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['A02.835.583.475'], ['M01.060.116.630'], ['H01.770.644.145.431', 'N04.761.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Controlled-release misoprostol vaginal insert in parous women for labor induction: a randomized controlled trial. | OBJECTIVE: To assess the ability of a controlled-release misoprostol vaginal insert to induce labor using dose reservoirs of 25, 50, 100, and 200 microg.METHODS: This double-blind, dose ranging, randomized study was carried out in parous women requiring induction of labor at term. Each woman was randomly assigned to re... | ['Administration, Intravaginal', 'Cesarean Section', 'Delayed-Action Preparations', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Humans', 'Infant, Newborn', 'Kaplan-Meier Estimate', 'Labor, Induced', 'Labor, Obstetric', 'Misoprostol', 'Oxytocics', 'Oxytocin', 'Pregnancy', 'Pregnancy Outcome', '... | 17,077,234 | [['E02.319.267.120.500'], ['E04.520.252.500'], ['D26.255.210', 'E02.319.300.253'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.318.740.998.650', 'N05.715.360.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Construction of a vector for the study of regulatory mechanism of gene expression and its utilization in the melibiose operon of Escherichia coli. | We constructed a vector to evaluate terminator or attenuator of transcription quantitatively. This vector is a plasmid possessing lac promoter-polylinker-CAT(chloramphenicol acetyltransferase) gene. DNA fragment of interest can be inserted into the polylinker site, and the effect of the DNA fragment on the expression o... | ['Cloning, Molecular', 'Disaccharides', 'Escherichia coli', 'Gene Expression Regulation', 'Genes', 'Genes, Bacterial', 'Genes, Regulator', 'Genetic Vectors', 'Melibiose', 'Membrane Transport Proteins', 'Operon', 'Symporters', 'Transcription, Genetic', 'alpha-Galactosidase'] | 2,852,352 | [['E05.393.220'], ['D09.698.629.305', 'D09.947.750'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.425'], ['G05.360.337'], ['D09.698.629.305.540', 'D09.947.750.54... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A thymidine to cytosine substitution for codon 26 of exon 3 of apolipoprotein C-II gene in a patient with apolipoprotein C-II deficiency. | A 52-year-old Japanese woman was evaluated for severe hypertriglyceridemia and recurrent acute pancreatitis. This hypertriglyceridemia was found to be due to the absence of serum apolipoprotein C-II (apo C-II) which was identified by Western blotting using polyclonal anti-apo C-II antiserum. DNA sequence analysis of th... | ['Apolipoprotein C-II', 'Apolipoproteins C', 'Blotting, Western', 'Codon', 'Cytosine', 'DNA', 'DNA Primers', 'Exons', 'Female', 'Humans', 'Hypertriglyceridemia', 'Middle Aged', 'Pancreatitis', 'Point Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Recurrence', 'Thymidine'] | 10,225,669 | [['D10.532.091.400.750', 'D12.776.070.400.400.750', 'D12.776.521.120.400.750'], ['D10.532.091.400', 'D12.776.070.400.400', 'D12.776.521.120.400'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Does and should breast cancer genetic counselling include lifestyle advice? | To optimally inform counselees about their and their relatives' risks, information about lifestyle risk factors, e.g. physical activity and alcohol consumption, might be discussed in breast cancer genetic counselling. This study explored whether lifestyle was discussed, on whose initiative, whether information and/or a... | ['Adult', 'Aged', 'BRCA1 Protein', 'Breast Neoplasms', 'Female', 'Genetic Counseling', 'Humans', 'Life Style', 'Middle Aged', 'Mutation', 'Risk Factors', 'Surveys and Questionnaires', 'Young Adult'] | 23,934,600 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['C04.588.180', 'C17.800.090.500'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['M01.060.116.630'], ['G05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The coexistence of psoriasis and lupus erythematosus. An analysis of 27 cases. | From 1950 through 1975, 27 patients at the Mayo Clinic, Rochester, Minn, had coexistent psoriasis and lupus erythematosus (LE). Of the 27 patients, ten had systemic LE (SLE), 13 had discoid LE, and four had drug-induced LE or an SLE-like syndrome. The onset of psoriasis preceded LE in ten patients and was concomitant w... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Lupus Erythematosus, Discoid', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Photosensitivity Disorders', 'Psoriasis', 'Skin'] | 7,377,802 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C17.300.475.479', 'C17.800.480.479'], ['C17.300.480', 'C20.111.590'], ['M01.060.116.630'], ['C17.800.600'], ['C17.800.859.675'], ['A17.81... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Antihypertensive treatment with eprosartan mesilate of patients in acute and late periods of ischemic stroke]. | Twenty patients with stroke of hemisphere localization developed as a result of arterial hypertension were treated with eprosartan mesilat. An estimation of the drug efficacy was conducted in comparison with other hypotensive medicines (control group). Eprosartan was used in dosage 600 mg daily. The study was carried o... | ['Acrylates', 'Acute Disease', 'Aged', 'Angiotensin II Type 1 Receptor Blockers', 'Antihypertensive Agents', 'Chi-Square Distribution', 'Data Interpretation, Statistical', 'Diastole', 'Female', 'Hemodynamics', 'Humans', 'Hypertension', 'Imidazoles', 'Male', 'Middle Aged', 'Quality of Life', 'Recurrence', 'Stroke', 'Sys... | 14,681,960 | [['D02.241.081.069'], ['C23.550.291.125'], ['M01.060.116.100'], ['D27.505.519.162.500'], ['D27.505.954.411.162'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
[New professional field in France: Analysis of the training needs of case managers]. | Case management is a relatively new career field in France. It was first introduced on an experimental basis in 2007-2008, and was then developedfollowing the National Alzheimer Plan and finally enshrined in legislation in 2012. This careerfield is based on a set of tasks widely described internationally: identifying t... | ['Aged, 80 and over', 'Case Management', 'Chronic Disease', 'Comorbidity', 'Delivery of Health Care', 'Education, Nursing, Continuing', 'Female', 'France', 'Health Personnel', 'Health Planning Support', 'Health Services Needs and Demand', 'Humans', 'Middle Aged', 'Universities', 'Workforce'] | 26,168,618 | [['M01.060.116.100.080'], ['N04.590.233.624.250'], ['C23.550.291.500'], ['N05.715.350.225', 'N06.850.490.687'], ['N04.590.374', 'N05.300'], ['I02.358.212.450', 'I02.358.462.399'], ['Z01.542.286'], ['M01.526.485', 'N02.360'], ['N03.219.483.408'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade. | Cotreatment with a minimally toxic concentration of the protein kinase C (PKC) activator (and down-regulator) bryostatin 1 (BRY) induced a marked increase in mitochondrial dysfunction and apoptosis in U937 monocytic leukemia cells exposed to the proteasome inhibitor lactacystin (LC). This effect was blocked by cyclohex... | ['Acetylcysteine', 'Amanitins', 'Aminoacetonitrile', 'Apoptosis', 'Benzoquinones', 'Bryostatins', 'Butadienes', 'Curcumin', 'Cysteine Endopeptidases', 'Dactinomycin', 'Diterpenes', 'Drug Synergism', 'Enzyme Activation', 'Flavonoids', 'Humans', 'Imidazoles', 'Indoles', 'JNK Mitogen-Activated Protein Kinases', 'Lactams, ... | 11,264,178 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['D04.345.566.050', 'D12.644.456.050', 'D12.644.641.050', 'D23.946.587.175'], ['D02.626.080.085'], ['G04.146.954.035'], ['D02.806.250'], ['D02.540.576.500.937'], ['D02.455.326.271.665.146.240'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Marijuana use among adults. A longitudinal study of current and former users. | This study examines the pattern of marijuana use among respondents who have passed the age of risk of onset, as well as some of the correlates related to the initiation and current use of marijuana. The data for this study included 8885 respondents drawn from the National Longitudinal Survey of Labor Market Experience ... | ['Adult', 'Age of Onset', 'Female', 'Follow-Up Studies', 'Humans', 'Logistic Models', 'Longitudinal Studies', 'Male', 'Marijuana Smoking', 'Outcome Assessment, Health Care', 'Prevalence', 'Time Factors'] | 11,367,600 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Early initiation of external beam radiotherapy (EBRT) may increase the risk of long-term toxicity in patients undergoing intraoperative radiotherapy (IORT) as a boost for breast cancer. | BACKGROUND: Intraoperative radiotherapy (IORT) during breast-conserving surgery is increasingly used. We analyzed the influence of the interval between an IORT boost and external beam radiotherapy (EBRT) on late toxicity.METHODS: Forty-eight patients received 20 Gy IORT (50 kV X-rays (Intrabeam, Carl Zeiss, Oberkochen,... | ['Breast Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Mastectomy, Segmental', 'Middle Aged', 'Radiation Injuries', 'Radiotherapy, Adjuvant', 'Risk Factors', 'Time Factors'] | 18,650,091 | [['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466.701'], ['M01.060.116.630'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E02.186.775', 'E02.81... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Timing of surgical intervention does not influence return of esophageal peristalsis or outcome for patients with achalasia. | BACKGROUND: It has been suggested that abnormal function of the lower esophageal sphincter is the primary abnormality in esophageal achalasia, and that the absence of esophageal peristalsis is secondary to the outflow obstruction caused by the lower esophageal sphincter. Furthermore, it has been proposed that early eli... | ['Esophageal Achalasia', 'Esophagus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peristalsis', 'Recovery of Function', 'Time Factors'] | 16,132,324 | [['C06.405.117.119.500.432'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G10.261.360.596'], ['G16.757'], ['G01.910.857']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Metallo-beta-lactamase-producing gram-negative rods isolated from inpatients and outpatients, detected using Etest MBL]. | The aim of presented study was to detect MBL-positive strains in a group of clinical carbapenem-resistant strains isolated from inpatients and outpatients during last four years. From the beginning of November 2001 to the end of October 2005, one hundred and four strains resistant to carbapenem antibiotics--imipenem an... | ['Anti-Bacterial Agents', 'Drug Resistance, Multiple, Bacterial', 'Gram-Negative Bacteria', 'Humans', 'Imipenem', 'Inpatients', 'Meropenem', 'Metals', 'Microbial Sensitivity Tests', 'Outpatients', 'Poland', 'Pseudomonas aeruginosa', 'Thienamycins', 'beta-Lactam Resistance', 'beta-Lactamases'] | 16,871,976 | [['D27.505.954.122.085'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B03.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.124.300.500', 'D03.633.100.300.124.300.500'], ['M01.643.470'], ['D02.065.589.099.124.300.750', 'D03.633.100.300.124.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Toxicity interaction between chlorpyrifos, mancozeb and soil moisture to the terrestrial isopod Porcellionides pruinosus. | A main source of uncertainty currently associated with environmental risk assessment of chemicals is the poor understanding of the influence of environmental factors on the toxicity of xenobiotics. Aiming to reduce this uncertainty, here we evaluate the joint-effects of two pesticides (chlorpyrifos and mancozeb) on the... | ['Animals', 'Chlorpyrifos', 'Drug Interactions', 'Feeding Behavior', 'Isopoda', 'Maneb', 'Pesticides', 'Soil', 'Soil Pollutants', 'Water', 'Zineb'] | 26,539,709 | [['B01.050'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['G07.690.773.968'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.500.131.365.400'], ['D02.241.081.251.869.265.441', 'D02.257.188', 'D02.886.706.250.500'], ['D27.720.031.700', 'D27.888.723'], ['D20.721', 'G01.311.82... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1. | Germline mutations in telomere biology genes cause dyskeratosis congenita (DC), an inherited bone marrow failure and cancer predisposition syndrome. DC is a clinically heterogeneous disorder diagnosed by the triad of dysplastic nails, abnormal skin pigmentation, and oral leukoplakia; Hoyeraal-Hreidarsson syndrome (HH),... | ['Adult', 'Aminopeptidases', 'Child', 'Child, Preschool', 'Dipeptidyl-Peptidases and Tripeptidyl-Peptidases', 'Dyskeratosis Congenita', 'Female', 'Fetal Growth Retardation', 'Germ-Line Mutation', 'HeLa Cells', 'Humans', 'Infant', 'Intellectual Disability', 'Male', 'Microcephaly', 'Models, Molecular', 'Mutation, Missens... | 25,233,904 | [['M01.060.116'], ['D08.811.277.656.350.100'], ['M01.060.406'], ['M01.060.406.448'], ['D08.811.277.656.350.350'], ['C15.378.190.223.500.750', 'C16.131.831.150', 'C16.320.322.108', 'C16.320.850.235', 'C17.800.804.150', 'C17.800.827.235'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['G05.365.590.350'], ['A11.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fetal growth: boys before girls. | At term birth, boys are heavier than girls. This difference is thought to be generated in part by androgen action; its time course has not been deciphered. Androgen action may not only increase weight gain, but may also alter its time course. We have tested this hypothesis by examining the difference in gestational age... | ['Birth Weight', 'Embryonic and Fetal Development', 'Female', 'Fetal Weight', 'Gestational Age', 'Humans', 'Male', 'Sex Characteristics'] | 10,559,673 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['G07.345.500.325', 'G08.686.784.170'], ['C23.888.144.300', 'E01.370.600.115.100.160.120.300', 'E05.041.124.160.750.300', 'G07.100.100.160.120.300', 'G07.345.249.314.120.300', 'G07.3... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measuring activity levels at an acute stroke ward: comparing observations to a device. | BACKGROUND: If a simple system of instrumented monitoring was possible early after stroke, therapists may be able to more readily gather information about activity and monitor progress over time. Our aim was to establish whether a device containing a dual-axis accelerometer provides similar information to behavioural m... | ['Aged', 'Aged, 80 and over', 'Equipment and Supplies', 'Female', 'Humans', 'Male', 'Motor Activity', 'Stroke', 'Stroke Rehabilitation'] | 24,282,815 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E07'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['C10.228.140.300.775', 'C14.907.253.855'], ['E02.760.169.063.500.477.500', 'E02.831.477.500', 'H02.403.680.600.750.500', 'N02.421.784.511.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
RNA-seq analysis identifies new genes regulated by the histone-like nucleoid structuring protein (H-NS) affecting Vibrio cholerae virulence, stress response and chemotaxis. | The histone-like nucleoid structuring protein (H-NS) functions as a transcriptional silencer by binding to AT-rich sequences at bacterial promoters. However, H-NS repression can be counteracted by other transcription factors in response to environmental changes. The identification of potential toxic factors, the expres... | ['Bacterial Proteins', 'Chemotaxis', 'Cholera', 'DNA-Binding Proteins', 'Gene Deletion', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'High-Throughput Nucleotide Sequencing', 'Indoles', 'Mutation', 'Promoter Regions, Genetic', 'Protein Binding', 'Quorum Sensing', 'Stress, Physiological', 'Trans... | 25,679,988 | [['D12.776.097'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['C01.150.252.400.959.347'], ['D12.776.260'], ['G05.365.590.762.320', 'G05.558.800.320'], ['E05.393.332'], ['G05.308.300'], ['E05.393.760.319'], ['D03.633.100.473'], ['G05.365.590'], ['... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neonates' vitamin A status in relation to birth weight, gestational age, and sex. | Vitamin A status was assessed in a randomly selected group of neonates at delivery. A total of 105 neonates were included in the study. Cord vitamin A concentration was determined by high performance liquid chromatography (HPLC). Of 105 neonates, 53 (50.5 per cent) were males and 49 49.5 per cent) were females. The mea... | ['Birth Weight', 'Female', 'Fetal Blood', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Male', 'Nutritional Status', 'Saudi Arabia', 'Sex Distribution', 'Vitamin A Deficiency'] | 9,680,787 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G07.203.650.650... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pattern generation in molecular evolution: exploitation of the variation in RNA landscapes. | Evolution of RNA secondary structure is studied using simulation techniques and statistical analysis of fitness landscapes. The transition from RNA sequence to RNA secondary structure leads to fitness landscapes that have local variations in their "ruggedness." Evolution exploits these variations. In stable environment... | ['Animals', 'Base Composition', 'Biological Evolution', 'Genetic Variation', 'Models, Genetic', 'Mutation', 'Nucleic Acid Conformation', 'RNA'] | 7,520,506 | [['B01.050'], ['G02.111.080'], ['G05.045', 'G16.075'], ['G05.365'], ['E05.599.395.397'], ['G05.365.590'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Perceived outcomes of psychedelic microdosing as self-managed therapies for mental and substance use disorders. | RATIONALE: The regular consumption of very small doses of psychedelic drugs (known as microdosing) has been a source of growing media and community attention in recent years. However, there is currently limited clinical and social research evidence on the potential role of microdosing as therapies for mental and substa... | ['Adult', 'Attention', 'Dose-Response Relationship, Drug', 'Female', 'Follow-Up Studies', 'Hallucinogens', 'Humans', 'Male', 'Mental Disorders', 'Mental Health', 'Motivation', 'Perception', 'Self-Management', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Treatment Outcome', 'Young Adult'] | 32,043,165 | [['M01.060.116'], ['F02.830.104.214'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D27.505.696.388', 'D27.505.954.427.700.372'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F02.418', 'N01.400.500'], ['F01.658', 'F01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inguinal Reconstruction Using Pedicled Rectus Abdominis Flap: A Useful Option for the Application of Radiotherapy. | Given their high rate of complications, radical surgical procedures of anorectal and gynecological tumors require a reliable and individualized reconstruction. The latter is influenced by the frequent indication of adjuvant chemo/radiotherapy that they present. We describe the case of a patient with medical history of ... | ['Abdominal Wound Closure Techniques', 'Adult', 'Female', 'Humans', 'Inguinal Canal', 'Radiotherapy', 'Reconstructive Surgical Procedures', 'Rectus Abdominis', 'Surgical Flaps', 'Treatment Outcome', 'Vulvar Neoplasms'] | 31,136,556 | [['E04.987.100'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.047.412'], ['E02.815'], ['E04.680'], ['A02.633.567.050.800'], ['A10.850.710', 'E07.862.710'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C04.588.945.418.968', 'C13.351.500.944.819', 'C13.351.937.418.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Percutaneous gastrostomy in a child. | A 2-year-old girl with cyanotic congenital heart disease needed to undergo gastrostomy. To avoid the use of general anesthesia, a percutaneous gastrostomy was performed as an interventional radiologic procedure with the patient under sedation and with the use of local anesthesia. The placement of a nasogastrocutaneous ... | ['Child, Preschool', 'Ebstein Anomaly', 'Female', 'Fluoroscopy', 'Gastrostomy', 'Humans', 'Intraoperative Care'] | 3,715,040 | [['M01.060.406.448'], ['C14.240.400.395', 'C14.280.400.395', 'C16.131.240.400.395'], ['E01.370.350.700.225'], ['E04.210.496', 'E04.579.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Value of subthalamic nucleus local field potentials recordings in predicting stimulation parameters for deep brain stimulation in Parkinson's disease. | OBJECTIVES: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) can be a highly effective treatment for Parkinson's disease. However, therapeutic efficacy can be limited by inconsistent targeting of this nucleus. It was shown previously that an increase in local field potential (LFP) power over the beta frequ... | ['Adult', 'Aged', 'Beta Rhythm', 'Deep Brain Stimulation', 'Electric Stimulation', 'Electrodes, Implanted', 'Electrophysiological Phenomena', 'Evoked Potentials', 'Female', 'Humans', 'Intraoperative Period', 'Male', 'Middle Aged', 'Parkinson Disease', 'Prospective Studies', 'Software', 'Stereotaxic Techniques', 'Subtha... | 20,466,699 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.376.300.150.750', 'E01.370.405.245.287.750', 'G07.265.087.750', 'G11.561.127.750'], ['E02.331.300', 'E04.190'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['G07.265'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Full-scale simulation of seawater reverse osmosis desalination processes for boron removal: Effect of membrane fouling. | The objective of this study is to further develop previously reported mechanistic predictive model that simulates boron removal in full-scale seawater reverse osmosis (RO) desalination processes to take into account the effect of membrane fouling. Decrease of boron removal and reduction in water production rate by memb... | ['Boron', 'Computer Simulation', 'Hydrogen-Ion Concentration', 'Membranes, Artificial', 'Osmosis', 'Salinity', 'Seawater', 'Waste Disposal, Fluid', 'Water Purification'] | 22,578,430 | [['D01.268.513.500'], ['L01.224.160'], ['G02.300'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['G02.640.500'], ['G16.500.275.725.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Mesocorticolimbic Connectivity and Volumetric Alterations in DCC | The axon guidance cue receptor DCC (deleted in colorectal cancer) plays a critical role in the organization of mesocorticolimbic pathways in rodents. To investigate whether this occurs in humans, we measured (1) anatomical connectivity between the substantia nigra/ventral tegmental area (SN/VTA) and forebrain targets, ... | ['Adult', 'Aging', 'Animals', 'Axons', 'DCC Receptor', 'Exploratory Behavior', 'Female', 'Heterozygote', 'Humans', 'Limbic System', 'Magnetic Resonance Imaging', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Middle Aged', 'Neural Pathways', 'Personality Disorders', 'Prefrontal Cortex', 'Substance-Related D... | 29,712,788 | [['M01.060.116'], ['G07.345.124'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D12.644.360.075.413', 'D12.776.476.075.413', 'D12.776.543.750.003.500', 'D12.776.624.776.021'], ['F01.145.387', 'F01.658.370'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autophagy as a new therapeutic target in Duchenne muscular dystrophy. | A resolutive therapy for Duchene muscular dystrophy, a severe degenerative disease of the skeletal muscle, is still lacking. Because autophagy has been shown to be crucial in clearing dysfunctional organelles and in preventing tissue damage, we investigated its pathogenic role and its suitability as a target for new th... | ['Animals', 'Autophagy', 'Disease Models, Animal', 'Humans', 'Male', 'Mice', 'Mice, Inbred mdx', 'Muscular Dystrophy, Duchenne', 'Oncogene Protein v-akt', 'Signal Transduction', 'TOR Serine-Threonine Kinases'] | 23,152,054 | [['B01.050'], ['G04.011'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420.500', 'B01.050.150.900.649.313.992.635.505.500.400.420.500', 'B01.050.150.900.649.313.992.635.505.500.550.265'], ['C05.651... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychological consequences of burn injury. | The major psychological sequelae experienced by patients 1 year after burn injury were investigated. Data were collected on a consecutive series of adult burn patients, (n = 55), including major demographic and epidemiological characteristics. Participants (n = 23) completed the Hospital Anxiety Depression Scale (HADS)... | ['Adult', 'Alcohol Drinking', 'Anxiety', 'Burns', 'Chronic Disease', 'Humans', 'Psychological Tests', 'Stress Disorders, Post-Traumatic', 'Surveys and Questionnaires'] | 1,793,497 | [['M01.060.116'], ['F01.145.317.269'], ['F01.470.132'], ['C26.200'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711'], ['F03.950.750.500'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct molecular interactions between Beclin 1 and the canonical NFêB activation pathway. | General (macro)autophagy and the activation of NFêB constitute prominent responses to a large array of intracellular and extracellular stress conditions. The depletion of any of the three subunits of the inhibitor of NFêB (IêB) kinase (IKKá, IKKâ, IKKã/NEMO), each of which is essential for the canonical NFêB activation... | ['Animals', 'Autophagy', 'Humans', 'Membrane Proteins', 'Models, Biological', 'NF-kappa B', 'Protein Binding', 'Signal Transduction'] | 22,301,997 | [['B01.050'], ['G04.011'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['E05.599.395'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['G02.111.679', 'G03.808'], ['G02.111.820', 'G04.835']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sleep quality varies as a function of 5-HTTLPR genotype and stress. | OBJECTIVE: To test the hypothesis that allelic variation in 5HTT gene-linked polymorphic region (5-HTTLPR) genotype was associated with sleep quality (Pittsburgh Sleep Quality Index, PSQI) as a main effect and as moderated by the chronic stress of caregiving. Serotonin (5HT) is involved in sleep regulation and the 5HT ... | ['Adult', 'Aged', 'Alleles', 'Caregivers', 'Case-Control Studies', 'Female', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Serotonin', 'Serotonin Plasma Membrane Transport Proteins', 'Severity of Illness Index', 'Sleep Wake Disorders', 'Stress, Psychological'] | 17,766,685 | [['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.795'], ['D02.092.211.215.801.852'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Diagnostic image (341). A man with left thoracic pain. Incarcerated diaphragmatic hernia of the transverse colon]. | A 28-year-old man with a previous (old) left thoracic stab wound, developed an incarcerated diaphragmatic hernia of the transverse colon which was repaired laparoscopically. | ['Abdominal Injuries', 'Adult', 'Colon', 'Hernia, Diaphragmatic, Traumatic', 'Humans', 'Male', 'Radiography', 'Thoracotomy', 'Treatment Outcome', 'Wounds, Stab'] | 17,929,713 | [['C26.017'], ['M01.060.116'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C23.300.707.960.500.233', 'C26.017.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['E04.928.760'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C26.986.950']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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