Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Baseline sensitivity and biochemical responses of Valsa mali to propamidine. | In the current study, baseline sensitivity of Valsa mali to propamidine was determined using 80 strains collected from apple orchards in Shaanxi Province, China. The median effective concentration (EC50) values for propamidine inhibiting mycelial growth ranged from 0.086 to 0.852 ìg/mL, with a mean of 0.405 ± 0.137 ìg/... | ['Adenosine Triphosphatases', 'Antifungal Agents', 'Ascomycota', 'Benzamidines', 'Cell Membrane Permeability', 'China', 'Electron Transport', 'Fruiting Bodies, Fungal', 'Hyphae', 'Malus', 'Microbial Sensitivity Tests', 'Mitochondria', 'Multienzyme Complexes', 'Plant Diseases', 'Plant Leaves'] | 29,933,998 | [['D08.811.277.040.025'], ['D27.505.954.122.136'], ['B01.300.107'], ['D02.078.100'], ['G03.143.335', 'G04.175'], ['Z01.252.474.164'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['A19.374'], ['A19.687.400'], ['B01.650.940.800.575.912.250.859.937.500.444'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Propofol Relaxes Isolated Rat Aorta through BKCa | BACKGROUND: Propofol is an intravenous anesthetic that can be used for the induction and maintenance of anesthesia. In the present study, it was aimed to investigate the mechanism of vasodilator action of propofol in the rat aorta (RA).METHODS: The RA rings were suspended in isolated organ baths and tension was recorde... | ['Animals', 'Aorta', 'Female', 'In Vitro Techniques', 'Large-Conductance Calcium-Activated Potassium Channel alpha Subunits', 'Propofol', 'Rats, Wistar', 'Signal Transduction', 'Vasodilation', 'Vasodilator Agents'] | 31,200,052 | [['B01.050'], ['A07.015.114.056'], ['E05.481'], ['D12.776.157.530.400.600.150.500.500', 'D12.776.543.550.450.750.150.500.500', 'D12.776.543.585.400.750.150.500.249'], ['D02.455.426.559.389.657.773'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G02.111.820', 'G04.835'], ['G09.330.380.928'], ['D27.505.954.411.918'... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacterial adherence to separated modular components in joint prosthesis: a clinical study. | Bacterial adherence on total joint replacement implants may lead to biofilm formation and implant-related osteoarticular infection. It is unclear if different biomaterials in the prosthetic components are more prone to facilitate this bacterial adherence, although ultrahigh molecular weight polyethylene (UHMWPE) compon... | ['Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Bacterial Adhesion', 'Biocompatible Materials', 'Humans', 'Joint Prosthesis', 'Materials Testing'] | 22,467,526 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['G06.099.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400'], ['E05.570']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Gr-1+ CD11b+ myeloid-derived suppressor cells suppress inflammation and promote insulin sensitivity in obesity. | Activation of immune cells, including macrophages and CD8(+) T cells, contributes significantly to the advancement of obesity and its associated medical complications, such as atherosclerosis, insulin resistance, and type 2 diabetes. However, how the activation of these immune cells is regulated in vivo remains largely... | ['Adipose Tissue', 'Animals', 'Apoptosis', 'CD11b Antigen', 'CD8-Positive T-Lymphocytes', 'Cell Differentiation', 'Cell Proliferation', 'Diabetes Mellitus, Type 2', 'Inflammation', 'Insulin Resistance', 'Macrophages', 'Mice', 'Mice, Obese', 'Myeloid Cells', 'Obesity', 'Receptors, Cell Surface'] | 21,592,961 | [['A10.165.114'], ['B01.050'], ['G04.146.954.035'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.776.543.750.705.408.100.150', 'D12.776.543.750.705.833.062', 'D23.050.301.350.074.049'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04.152'],... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Initial experience with a new type of high energy neodymium laser in correcting stenosis of the airway]. | The aim of the study was to assess the use of a new Nd:YAG laser--mediLas fibertom--in correcting malignant and benign stenoses of the airways. Eighteen patients were included in the study. In 9 these were caused by malignant tumors, in 3 by nonmalignant tumors, in 6 by post-inflammatory stenoses of the airways. Altoge... | ['Adolescent', 'Adult', 'Aged', 'Airway Obstruction', 'Bronchoscopy', 'Female', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Respiratory Tract Diseases'] | 7,633,370 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C08.618.846.185'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['C08']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cloning the Yarrowia lipolytica homologue of the Saccharomyces cerevisiae SEC62 gene. | Yarrowia lipolytica SEC62 cDNA was cloned by functional complementation of a thermo-sensitive sec62 Saccharomyces cerevisiae mutant strain. The Y. lipolytica SEC62 promoter region was amplified by the inverse polymerase chain reaction (PCR). The cDNA codes for a 396 amino-acid protein with two potential trans-membrane ... | ['Amino Acid Sequence', 'Blotting, Western', 'Cloning, Molecular', 'DNA, Complementary', 'DNA, Fungal', 'Escherichia coli', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Gene Library', 'Genetic Complementation Test', 'Membrane Proteins', 'Membrane Transport Proteins', 'Molecular Sequence Data', 'Polymerase ... | 9,021,129 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D13.444.308.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A serologic assessment of exposure to viral pathogens and Leptospira in an urban raccoon (Procyon lotor) population inhabiting a large zoological park. | In urban environments, raccoons (Procyon lotor) may act as reservoirs for an array of pathogenic organisms, presenting spillover risks for human, domestic animal, and captive (zoo) animal populations. Over 5 yr, 159 raccoons from a high-density raccoon population in St. Louis, Missouri (USA), were surveyed for exposure... | ['Adenoviridae', 'Adenoviridae Infections', 'Animals', 'Animals, Zoo', 'Antibodies, Bacterial', 'Antibodies, Viral', 'Disease Reservoirs', 'Distemper', 'Distemper Virus, Canine', 'Feline Panleukopenia Virus', 'Female', 'Leptospira', 'Leptospirosis', 'Male', 'Parvoviridae Infections', 'Raccoons', 'Seroepidemiologic Stud... | 17,469,271 | [['B04.280.030'], ['C01.925.256.076'], ['B01.050'], ['B01.050.050.448'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['N06.850.520.203.250'], ['C01.925.782.580.600.500.285', ... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
New Cytotoxic Secondary Metabolites from Marine Bryozoan Cryptosula pallasiana. | A new sterol, (23R)-methoxycholest-5,24-dien-3â-ol (1), two new ceramides, (2S,3R,4E,8E)-2-(tetradecanoylamino)-4,8-octadecadien-l,3-diol (6) and (2S,3R,2'R,4E,8E)-2-(tetradecanoylamino)-4,8-octadecadien-l,3,2'-triol (7), together with three known sterols (2-4), a lactone (5) and two ceramides (8,9), were isolated from... | ['Animals', 'Aquatic Organisms', 'Bryozoa', 'Cell Line, Tumor', 'Ceramides', 'China', 'Fatty Acids', 'HL-60 Cells', 'Hep G2 Cells', 'Humans', 'Molecular Structure', 'Sterols'] | 28,406,457 | [['B01.050'], ['B05.080', 'G16.500.275.725.500.650.075'], ['B01.050.500.217'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['Z01.252.474.164'], ['D10.251'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome. | BACKGROUND: X monosomic mice (39,XO) have a remarkably mild phenotype when compared to women with Turner syndrome (45,XO). The generally accepted hypothesis to explain this discrepancy is that the number of genes on the mouse X chromosome which escape X inactivation, and thus are expressed at higher levels in females, ... | ['Alleles', 'Animals', 'Female', 'Gene Expression Profiling', 'Gene Regulatory Networks', 'Genes, X-Linked', 'Mice', 'Oligonucleotide Array Sequence Analysis', 'Transcription, Genetic', 'Turner Syndrome', 'X Chromosome', 'X Chromosome Inactivation'] | 20,122,165 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.393.332'], ['G05.360.080.689.360'], ['G05.360.340.024.340.500', 'G05.420.457'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['G02.111.873', 'G05.297.700'], ['C12.706.316.309.872', 'C12.706.316.795... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Corticosteroids impair intestinal epithelial wound repair mechanisms in vitro. | BACKGROUND: Despite enormous progress in the medical treatment of inflammatory bowel diseases (IBD), corticosteroids still represent the most effective drugs in the management of acute IBD. Unfortunately, surgical intervention under concomitant therapy with corticosteroids is often complicated by impaired intestinal wo... | ['Anti-Inflammatory Agents', 'Apoptosis', 'Budesonide', 'Cell Division', 'Cell Movement', 'Enzyme-Linked Immunosorbent Assay', 'Epithelial Cells', 'HT29 Cells', 'Humans', 'In Vitro Techniques', 'Intestines', 'Prednisolone', 'Reverse Transcriptase Polymerase Chain Reaction', 'Transforming Growth Factor beta', 'Wound Hea... | 11,521,988 | [['D27.505.954.158'], ['G04.146.954.035'], ['D04.210.500.745.745.654.105'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.436'], ['A11.25... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
c-Jun N-terminal kinase 1/2 activation by tumor necrosis factor-alpha induces insulin resistance in human visceral but not subcutaneous adipocytes: reversal by liver X receptor agonists. | AIMS: Obesity is associated with a chronic systemic low-grade inflammatory state. Markers of inflammation such as TNF-alpha are linked with increased risk for insulin resistance and type 2 diabetes. The objective of the present study was to dissect the molecular mechanisms that may regulate TNF-alpha-induced insulin re... | ['AMP-Activated Protein Kinases', 'Adipocytes', 'Cell Line, Tumor', 'DNA-Binding Proteins', 'Glucose', 'Glucose Transporter Type 1', 'Glucose Transporter Type 4', 'Humans', 'Insulin Receptor Substrate Proteins', 'Insulin Resistance', 'Intra-Abdominal Fat', 'Liver X Receptors', 'Mitogen-Activated Protein Kinase 8', 'Mit... | 19,567,513 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['A11.329.114'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.260'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500.500', 'D12.776.157.530.937.563.500', 'D12.776.543.585.500.500.500', 'D12.776.543.585.937.625.500'], ['D12.776.157.530.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of the lipid component of the medium on lipase biosynthesis by fungi]. | The lipolytic activity of the fungi Aspergillus and Rhizopus was studied on a medium with soybean flour. The lipolytic activity of the Aspergillus fungi was low or absent whereas many of the cultures belonging to the Rhizopus genus possessed the lipolytic activity. The effect of soybean flour components on lipase biosy... | ['Aspergillus', 'Culture Media', 'Lipase', 'Lipid Metabolism', 'Lipolysis', 'Rhizopus', 'Soybeans'] | 573,367 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Salmonella | Strains of Salmonella utilize two distinct type three secretion systems to deliver effector proteins directly into host cells. The Salmonella effectors SseK1 and SseK3 are arginine glycosyltransferases that modify mammalian death domain containing proteins with N-acetyl glucosamine (GlcNAc) when overexpressed ectopical... | ['Acetylglucosamine', 'Animals', 'Bacterial Proteins', 'Conserved Sequence', 'Glutamic Acid', 'Glycosylation', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'Mutagenesis', 'Mutation', 'Protein Domains', 'RAW 264.7 Cells', 'Receptors, TNF-Related Apoptosis-Inducing Ligand', 'Receptors, Tumor Necr... | 30,902,834 | [['D09.067.342.531.050'], ['B01.050'], ['D12.776.097'], ['G02.111.570.580'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of DA-9701 on gastric emptying in a mouse model: assessment by ?³C-octanoic acid breath test. | AIM: To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the ?³C-octanoic acid breath test in a mouse model.METHODS: Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 mg of egg yolk labeled with 1.5 L/g ?³C-octanoic ... | ['Animals', 'Body Weight', 'Breath Tests', 'Caprylates', 'Carbon Isotopes', 'Cross-Over Studies', 'Disease Models, Animal', 'Erythromycin', 'Gastric Emptying', 'Gastrointestinal Agents', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Plant Preparations', 'Random Allocation', 'Reproducibility of Results', 'Time Factors'] | 23,885,150 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.100'], ['D02.241.081.222', 'D10.251.122'], ['D01.268.150.075', 'D01.496.123'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C22.232', 'E05.598.500', 'E05.5... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The association of wildfire smoke with respiratory and cardiovascular emergency department visits in Colorado in 2012: a case crossover study. | BACKGROUND: In 2012, Colorado experienced one of its worst wildfire seasons of the past decade. The goal of this study was to investigate the relationship of local PM2.5 levels, modeled using the Weather Research and Forecasting Model with Chemistry, with emergency department visits and acute hospitalizations for respi... | ['Adolescent', 'Adult', 'Aged', 'Air Pollutants', 'Cardiovascular Diseases', 'Child', 'Child, Preschool', 'Colorado', 'Emergency Service, Hospital', 'Environmental Exposure', 'Fires', 'Humans', 'Infant', 'Infant, Newborn', 'Middle Aged', 'Models, Theoretical', 'Particulate Matter', 'Respiratory Tract Diseases', 'Smoke'... | 27,259,511 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.888.284.101'], ['C14'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.567.875.760.210'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N06.850.460.350'], ['N06.230.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Open-heart surgery in a patient with heterozygous alpha 2-antiplasmin deficiency. Perioperative strategies in the first reported case. | alpha 2-Antiplasmin deficiency is a serious coagulation disorder that results in unrestrained fibrinolytic activity. Clinically, it is manifested by instability of the fibrin hemostatic plug and prolonged or delayed bleeding, which is more serious in patients who are homozygous for this trait. A patient scheduled for a... | ['Aged', 'Aortic Valve', 'Blood Coagulation Disorders', 'Coronary Artery Bypass', 'Fibrinolysin', 'Heart Valve Prosthesis', 'Hemostasis, Surgical', 'Heterozygote', 'Humans', 'Male', 'Plasmapheresis', 'Preoperative Care', 'alpha-2-Antiplasmin', 'alpha-Macroglobulins'] | 1,693,328 | [['M01.060.116.100'], ['A07.541.510.110'], ['C15.378.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['E07.695.310'], ['E02.520.490', 'E04.350'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.120.770'... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Model-based hypothesis of gut microbe populations and gut/brain barrier permeabilities in the development of regressive autism. | Regressive autism is a devastating disorder affecting children between the ages of 15-30 months. The disorder is characterized by the loss of social interaction and communication ability following otherwise healthy development. In spite of rising autism prevalence, current detection methods and treatment options for th... | ['Animals', 'Autistic Disorder', 'Bacteroides', 'Blood-Brain Barrier', 'Child, Preschool', 'Computer Simulation', 'Cytokines', 'Humans', 'Infant', 'Inflammation', 'Intestines', 'Models, Biological', 'Neurotoxins', 'Permeability', 'Propionates', 'Rats', 'Time Factors', 'Virulence'] | 25,288,537 | [['B01.050'], ['F03.625.164.113.500'], ['B03.440.080.094.152', 'B03.440.425.410.194.152'], ['A07.035', 'A08.186.211.035'], ['M01.060.406.448'], ['L01.224.160'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C23.550.470'], ['A03.556.124'], ['E0... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Named Groups [M]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Pain, the elderly and verbal communication disorders]. | The prevalence of pain increases with age and multiple pathologies. Care procedures and movement are often triggers: dressings, injections, perfusions, washing, changes, transfers, walking, meals, etc. Which tools should be used when speech is lacking? What are the challenges in geriatrics for the patient and the careg... | ['Aged', 'Communication Disorders', 'Geriatric Assessment', 'Humans', 'Pain'] | 25,055,588 | [['M01.060.116.100'], ['C10.597.606.150', 'C23.888.592.604.150', 'F03.625.374'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. | To investigate the cellular mechanism of insulinotropic effect of glutamate in pancreatic beta cells, we utilized patch-clamp technique to monitor directly the activities of ATP-sensitive potassium channels (K(ATP) channels). Dimethylglutamate (5mM), a membrane-permeable analog of glutamate, augmented the insulin relea... | ['Adenosine Triphosphate', 'Animals', 'Cell Line', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Glucose', 'Glutamic Acid', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Male', 'Mice', 'Patch-Clamp Techniques', 'Potassium', 'Potassium Channels', 'Rats', 'Rats, Wistar'] | 14,623,322 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.251.210'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.947.875.359.448'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Familias Saludables partnership: Engaging the Latino community to address early childhood obesity. | Darcy A Thompson is an Associate Professor of pediatrics at the University of Colorado School of Medicine. Her main research seeks to address early childhood obesity in low-income children. She works in the Lifestyle Medicine clinic at Children's Hospital Colorado, a clinic focused on caring for children with obesity a... | ['Advisory Committees', 'Child, Preschool', 'Colorado', 'Female', 'Hispanic Americans', 'Humans', 'Infant', 'Infant, Newborn', 'Interprofessional Relations', 'Pediatric Obesity'] | 29,464,967 | [['N03.706.742.500'], ['M01.060.406.448'], ['Z01.107.567.875.760.210'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['F01.829.401.205'], ['C18.654.726.500.720', 'C23.888.144.699.500.750', 'E01.370.600.115.100.160.120.699.500.750', 'G07.100.100.160.120.699.... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of posterior temporal-parietal hematoma on orbital frontal chemistry in relation to a cognitive and anxiety state: a combined 1H-MRS and neuropsychological study of an unusual case as compared with 16 healthy subjects. | The authors report the unusual case of a 58-year-old woman (MJP) suffering from left temporal throbbing headache, associated with confusion. Magnetic resonance imaging showed a 5 x 3 x 2 cm hematoma at the left posterior temporal--parietal junction (PTPJ). Repeated MRI of MJP's brain performed during a 4-month follow-u... | ['Anxiety', 'Cognition Disorders', 'Confusion', 'Female', 'Frontal Lobe', 'Headache', 'Hematoma', 'Humans', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Middle Aged', 'Neuropsychological Tests', 'Orbit', 'Parietal Lobe', 'Psychiatric Status Rating Scales', 'Temporal Lobe'] | 11,861,128 | [['F01.470.132'], ['F03.615.250'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['A08.186.211.200.885.287.500.270'], ['C23.888.592.612.441'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['M01.060.116.630'], ['F04.711.513'], ['A02.835.... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Melissa officinalis L. ethanolic extract inhibits the growth of a lung cancer cell line by interfering with the cell cycle and inducing apoptosis. | Melissa officinalis is a plant from the family Lamiaceae, native in Europe particularly in the Mediterranean region. Given our interest in identifying extracts and compounds capable of inhibiting tumor cell growth, and given the antioxidant content and the high consumption of Melissa officinalis in Portugal, this study... | ['Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Humans', 'Lung Neoplasms', 'Melissa', 'Plant Extracts'] | 29,790,547 | [['D27.505.954.248.179'], ['G04.146.954.035'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.650.940.800.575.912.250.583.520.474'], ['D20.215.784.500', 'D26.667']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Curcumin inhibits proliferation of human lens epithelial cells: a proteomic analysis. | OBJECTIVE: The incidence of after-cataracts [also known as posterior capsular opacification (PCO)] is between 30% and 50% three years following cataract surgery. Suppressing the proliferation of lens epithelial cells (LECs) is a primary goal in preventing PCO. Here, we investigated the proteomic regulation of the inhib... | ['Cell Line', 'Cell Proliferation', 'Curcumin', 'Epithelial Cells', 'Humans', 'Lens, Crystalline', 'Proteome'] | 22,556,179 | [['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.500'], ['D12.776.817']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The E-cigarette Social Environment, E-cigarette Use, and Susceptibility to Cigarette Smoking. | PURPOSE: One concern regarding the recent increase in adolescent e-cigarette use is the possibility that electronic (e-) cigarettes may be used by those who might not otherwise have used cigarettes, and that dual use, or transition to cigarette use alone, may follow.METHODS: Questionnaire data were obtained in 2014 fro... | ['Adolescent', 'Adolescent Behavior', 'Cross-Sectional Studies', 'Electronic Nicotine Delivery Systems', 'Female', 'Humans', 'Male', 'Peer Influence', 'Risk', 'Smoking', 'Social Environment', 'Students', 'Surveys and Questionnaires', 'Tobacco Products', 'United States'] | 27,161,417 | [['M01.060.057'], ['F01.145.022'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['J01.637.767.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.483.750'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['F01.145.805'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Pharmacokinetics of 2-(alpha-thenoylthio)-propionylglycine (TTPG) in healthy volunteers--an oral dose-proportionality investigation. | The dose linearity of 2-(alpha-thenoylthio)-propionylglycine (TTPG) pharmacokinetics after a single oral administration at three different TTPG doses (180, 540 and 1080 mg) was evaluated in 12 healthy volunteers according to an open, randomized, cross-over study with a 1-week wash-out period between each administration... | ['Adult', 'Carboxylic Acids', 'Chromatography, High Pressure Liquid', 'Expectorants', 'Female', 'Glycine', 'Half-Life', 'Humans', 'Male', 'Spectrophotometry, Ultraviolet', 'Sulfides', 'Thiophenes', 'Tiopronin'] | 1,286,128 | [['M01.060.116'], ['D02.241'], ['E05.196.181.400.300'], ['D27.505.954.796.250'], ['D12.125.481'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520'], ['D02.886.778', 'D03.383.903'], ['D02.886.030.896... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chemopreventive effects of coumaperine from pepper on the initiation stage of chemical hepatocarcinogenesis in the rat. | This study was designed to investigate the chemopreventive action of three natural products, coumaperine, aurapten and an extract from rosemary, against the initiation stage of rat hepato-carcinogenesis. Coumaperine has been isolated from white pepper as a naturally occurring antioxidative agent, but its potential modi... | ['Animals', 'Anticarcinogenic Agents', 'Apoptosis', 'Carcinogens', 'Cell Division', 'Coumarins', 'Diethylnitrosamine', 'Gene Expression', 'Glutathione Transferase', 'Immunohistochemistry', 'Lamiaceae', 'Liver', 'Liver Neoplasms, Experimental', 'Male', 'Nucleolus Organizer Region', 'Piperidines', 'Plant Extracts', 'Prol... | 10,920,273 | [['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['G04.146.954.035'], ['D27.888.569.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D02.654.442.200'], ['G05.297'], ['D08.811.913.225.500'], ['E01.370.225.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Cardio-facio-cutaneous syndrome: three additional cases and review of the literature. | We report on 3 patients with the cardio-facio-cutaneous (CFC) syndrome. Each of them was a sporadic case in the family. The severity of the psychomotor retardation varied from mild to severe. Skin manifestations were often minimal, but each patient had abnormally curly and brittle hair. A skin biopsy from one of the pa... | ['Diagnosis, Differential', 'Facial Bones', 'Female', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Infant, Newborn', 'Psychomotor Disorders', 'Skin Abnormalities', 'Skull', 'Syndrome'] | 1,481,834 | [['E01.171'], ['A02.835.232.781.324'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C10.597.606.881', 'C23.888.592.604.882', 'F01.700.875'], ['C16.131.831', 'C17.800.804'], ['A02.835.232.781'], ['C23.550.288.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
International emergency medicine: a review of the literature. | The field of international emergency medicine has grown rapidly over the past several decades, with an increase in the number of interested individuals and in the range of topics included under its rubric. One of the greatest obstacles, however, faced by international emergency medicine researchers and practitioners al... | ['Emergency Medicine', 'Evidence-Based Medicine', 'Global Health', 'Review Literature as Topic', 'Societies, Medical'] | 17,192,444 | [['H02.403.250'], ['H02.249.750', 'H02.403.200.400'], ['H02.403.371', 'N01.400.337'], ['L01.178.682.759'], ['N03.540.828.589']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-â and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells. | Application of chondroreparative gene vectors in cartilage defects is a powerful approach to directly stimulate the regenerative activities of bone-marrow-derived mesenchymal stem cells (MSCs) that repopulate such lesions. Here, we investigated the ability of combined recombinant adeno-associated virus (rAAV) vector-me... | ['Cell Differentiation', 'Cells, Cultured', 'Chondrocytes', 'Chondrogenesis', 'Gene Transfer Techniques', 'Genetic Vectors', 'Humans', 'Insulin-Like Growth Factor I', 'Mesenchymal Stem Cells', 'Parvovirinae', 'Transforming Growth Factor beta'] | 31,137,788 | [['G04.152'], ['A11.251'], ['A11.329.171'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['E05.393.350'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['A11.329.830.500', 'A11.872.590.500'], ['B04.280.5... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lack of seasonality of Amblyomma rotundatum (Acari: Ixodidade) on Rhinella jimi (Anura: Bufonidae) in a semi-arid region of northeastern Brazil. | Amblyomma rotundatum is an ixodid tick strictly associated with cold-blooded animals, among them the toad Rhinella jimi. This work aimed to evaluate the seasonal dynamics of larvae, nymphs, and adults of A. rotundatum parasitizing R. jimi in an area within the semi-arid Caatinga Biome of northeastern Brazil. Monthly sa... | ['Animals', 'Brazil', 'Bufonidae', 'Desert Climate', 'Female', 'Ixodidae', 'Larva', 'Nymph', 'Population Dynamics', 'Seasons', 'Tick Infestations', 'Ticks'] | 29,934,040 | [['B01.050'], ['Z01.107.757.176'], ['B01.050.150.900.090.180.210'], ['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['B01.050.500.131.166.132.832.400'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B05.500.650', 'G07.345.500.550.500.650'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.910.645.661', ... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Size distribution of artificial and natural radioactive aerosols in the 30-kilometer zone of the Chernobyl AES in 1986-1996]. | During 10 years after the Chernobyl accident the systematical measurings of size distributions of radioactive aerosols were conducted near the block-IV. In the ground level the active median aerodynamic diameters (AMAD) of 137Cs aerosols were ranged from 0.4 up to 1.4 microns in May, 1986. In that time the aerosol carr... | ['Aerosols', 'Air Pollutants, Radioactive', 'Beryllium', 'Cesium Radioisotopes', 'Filtration', 'Lead Radioisotopes', 'Power Plants', 'Radioactive Hazard Release', 'Radioisotopes', 'Radon', 'Radon Daughters', 'Time Factors', 'Ukraine'] | 9,889,783 | [['D20.280.055', 'D26.255.165.055'], ['D20.693.101', 'D27.888.284.101.393'], ['D01.268.552.075', 'D01.268.557.080', 'D01.552.547.080'], ['D01.268.549.125.500.300', 'D01.268.556.165.500.300', 'D01.496.180.300', 'D01.496.749.190', 'D01.552.528.160.500.300', 'D01.552.544.165.500.300'], ['E05.196.454', 'G01.280', 'G02.263'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Immunochemical isolation and characterization of vitellogenin mRNA from liver of estradiol-treated chicks. | Vitellogenin mRNA was purified through three steps. A heavy polysome fraction was obtained by discontinuous sucrose density gradient centrifugation, vitellogenin polysomes were immunoprecipitated with affinity-chromatography-purified anti-lipovitellin IgG and goat anti-rabbit IgG, the enriched mRNA was isolated on a po... | ['Animals', 'Chickens', 'Estradiol', 'Female', 'Kinetics', 'Lipoproteins', 'Liver', 'Male', 'Polyribosomes', 'Precipitin Tests', 'Protein Biosynthesis', 'RNA, Messenger', 'Vitellogenins'] | 947,754 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G01.374.661', 'G02.111.490'], ['D10.532', 'D12.776.521'], ['A03.620'], ['A11.284.430.214.190.875.811.740'], ['E01.370.225.812.735.645', 'E05.196.150.639.500', 'E05.200.812.735.645', 'E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extracorporeal membrane oxygenation resuscitation for traumatic brain injury after decompressive craniotomy. | Acute cardiopulmonary failure in patients with increased intracranial pressure is a significant management challenge to physicians. We report on a 21-year-old patient with traumatic brain injury who developed intractable hypoxemia and hypotension after undergoing a decompressive craniotomy. Venoarterial extracorporeal ... | ['Adult', 'Brain', 'Brain Injuries', 'Decompression, Surgical', 'Extracorporeal Membrane Oxygenation', 'Glasgow Coma Scale', 'Humans', 'Hypoxia, Brain', 'Intracranial Hypotension', 'Intraoperative Complications', 'Male', 'Neurosurgical Procedures', 'Resuscitation', 'Tomography, X-Ray Computed'] | 18,068,892 | [['M01.060.116'], ['A08.186.211'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E04.188'], ['E02.880.301', 'E04.292.451'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.624', 'C... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A standardized densitometric immunoblotting analysis of Candida albicans protein allergens. | Sera from 196 patients with a strong skin reactivity to Candida albicans and a history of atopic disease were used for C. albicans IgE-immunoblotting. The IgE-immunoblots were analysed by densitometry and integration of the densitogram peaks. A standardized reference disc system allowed parallel analysis of several dif... | ['Allergens', 'Candida albicans', 'Densitometry', 'Fungal Proteins', 'Humans', 'Immunoblotting', 'Immunoglobulin E'] | 7,600,382 | [['D23.050.063'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['E05.196.712.224'], ['D12.776.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thigh musculature in relation to chronic anterior cruciate ligament tear: muscle size, morphology, and mechanical output before reconstruction. | Eighteen male patients who had untreated chronic ACL rupture were studied in order to evaluate thigh muscle size, morphology, and isokinetic performance of the quadriceps muscle. Computed tomography disclosed a 5.1% mean atrophy of the quadriceps (P less than 0.05), 2.1% slight hypertrophy of the hamstrings (P less tha... | ['Adult', 'Chronic Disease', 'Humans', 'Joint Instability', 'Knee Injuries', 'Ligaments, Articular', 'Male', 'Muscles', 'Rupture', 'Thigh'] | 2,729,494 | [['M01.060.116'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['C26.558.554'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['A02.633', 'A10.690'], ['C26.761'], ['A01.378.610.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Studies on Streptococcus faecalis enterotoxin. | Streptococcus faecalis has been reported to cause food poisoning. Six strains of S. faecalis were tested for Sherman's criteria. These strains were non-hemolytic, DNase+ and Ent+. The enterotoxin was purified on Sephadex G-200 column and maximum activity was observed at 37 C and pH 7.0. Enterotoxin treated with trypsin... | ['Acridine Orange', 'Animals', 'Anti-Bacterial Agents', 'Deoxyribonucleases', 'Enterococcus faecalis', 'Enterotoxins', 'Ethidium', 'Hydrogen-Ion Concentration', 'Rabbits', 'Temperature'] | 2,442,976 | [['D03.633.300.046.250.150'], ['B01.050'], ['D27.505.954.122.085'], ['D08.811.277.352.335'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['D23.946.330'], ['D03.633.300.633.416'], ['G02.300'], ['B01.050.150.900.649.313.968.700'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Impact of near freezing temperature storage on postharvest quality and antioxidant capacity of two apricot (Prunus armeniaca L.) cultivars. | To reduce the postharvest loss and improve apricot quality attributes, near freezing temperature (NFT) technology was applied to store apricot cultivars (var. "Xiaobai" and "Daliguang"). The NFT storage temperatures for the "Xiaobai" apricot and "Daliguang" apricot were determined as -1.9 to -2.3°C and -1.2 to -1.6°C, ... | ['Antioxidants', 'Ascorbic Acid', 'Cold Temperature', 'Ethylenes', 'Flavonoids', 'Food Storage', 'Free Radical Scavengers', 'Fruit', 'Malondialdehyde', 'Phenols', 'Prunus armeniaca', 'Respiratory Rate'] | 31,353,735 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D02.455.326.271.367'], ['D03.383.663.283.266.450', 'D0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A non-P-glycoprotein-mediated mechanism of vincristine transport which is affected by resistance modifiers and present in chemosensitive cells. | The accumulation and cytotoxicity of vincristine (Vcr), etoposide (VP16), and daunorubicin (Dau) and effect of the resistance modifiers (RM) verapamil (Ver; 10 microM) and cyclosporin A (CyA; 3 microM) were studied in isolated rat cardiac myocytes, peripheral lymphocytes from seven patients with chronic lymphocytic leu... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Animals', 'Biological Transport', 'Carrier Proteins', 'Cell Survival', 'Cells, Cultured', 'Cyclosporine', 'Daunorubicin', 'Drug Interactions', 'Drug Resistance', 'Drug Screening Assays, Antitumor', 'Gene Expression', 'Heart', 'Humans', 'Leukemia, Experimental... | 7,911,547 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['B01.050'], ['G03.143'], ['D12.776.157'], ['G04.346'], ['A11.251'], ['D04.345.566.235.300', 'D12.644.641.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated YB-1 expression is a new unfavorable prognostic factor in non-Hodgkin's lymphomas. | BACKGROUND: Y-Box-binding protein-1 (YB-1) acts as a transcription factor for multiple genes and is linked to DNA replication and repair, cell proliferation and resistance to cytostatic drugs.PATIENTS AND METHODS: The prognostic value of YB-1 expression in primarily untreated malignant non-Hodgkin's lymphomas (NHLs) wa... | ['Adult', 'Disease-Free Survival', 'Female', 'Humans', 'Immunohistochemistry', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Prognosis', 'Y-Box-Binding Protein 1'] | 21,868,545 | [['M01.060.116'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.51... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
River restoration success depends on the species pool of the immediate surroundings. | Previous studies evaluating the success of river restorations have rarely found any consistent effects on benthic invertebrate assemblages. In this study, we analyzed data from 24 river restoration projects in Germany dating back 1 to 12 years and 1231 data sets from adjacent river reaches that lie within 0-5, 5-10, an... | ['Animals', 'Conservation of Natural Resources', 'Ecosystem', 'Environmental Monitoring', 'Environmental Restoration and Remediation', 'Invertebrates', 'Population Dynamics', 'Rivers'] | 21,939,037 | [['B01.050'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.230.080.600', 'N06.850.460.375'], ['B01.050.500'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Neurogenic adaptation contributes to the afferent response to mechanical stimulation. | This study aimed to characterize the effect of mechanical stimuli on mesenteric afferent nerve signaling in the isolated rat jejunum in vitro. This was done to determine the effect of mechanical stresses and strains relative to nonmechanical parameters (neurogenic adaptation). Mechanical stimulations were applied to a ... | ['Adaptation, Physiological', 'Afferent Pathways', 'Animals', 'Jejunum', 'Male', 'Mechanoreceptors', 'Mechanotransduction, Cellular', 'Neurogenesis', 'Neuronal Plasticity', 'Physical Stimulation', 'Rats', 'Rats, Wistar'] | 22,345,553 | [['G07.025', 'G16.012.500'], ['A08.612.220'], ['B01.050'], ['A03.556.124.684.500', 'A03.556.249.750'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['G01.154.090.500', 'G02.111.820.580', 'G04.835.580'], ['G04.152.912', 'G07.345.500.325.377.687', 'G08.686.784.170.450.500', 'G11.561.620'], ['G11.561... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Verbal priming and taste sensitivity make moral transgressions gross. | The aims of the present study were to assess whether: (a) visceral and moral disgust share a common oral origin (taste); (b) moral transgressions that are also viscerally involving are evaluated accordingly as a function of individual differences in taste sensitivity; (c) verbal priming interacts with taste sensitivity... | ['Adolescent', 'Affect', 'Emotions', 'Female', 'Humans', 'Male', 'Morals', 'Repetition Priming', 'Sex Factors', 'Taste Perception', 'Young Adult'] | 24,512,062 | [['M01.060.057'], ['F01.470.047'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['F02.463.425.540.739'], ['N05.715.350.675', 'N06.850.490.875'], ['F02.463.593.817'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Local labor markets, children and labor force participation of wives. | Most research on married women's labor force participation relates characteristics of individual women to their probability of labor force participation. Some studies relate characteristics of geographic areas to average labor force participation rates in those areas, although these aggregate level analyses are usually... | ['Adolescent', 'Adult', 'Child', 'Child Care', 'Child, Preschool', 'Employment', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Models, Theoretical', 'Probability', 'United States', 'Women', 'Women, Working'] | 6,734,855 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['I01.880.787.293.360', 'N02.421.088'], ['M01.060.406.448'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.599'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['Z01.107.56... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Spontaneous cutaneous mast cell tumor with lymph node metastasis in a Richardson's ground squirrel (Spermophilus richardsonii). | A 4-year-old female Richardson's ground squirrel (Spermophilus richardsonii) presented with multicentric nodules arising from the skin of the middle of the tail and lumbosacral regions. Histologically, the nodules were composed of a proliferation of spindloid to pleomorphic cells that sometimes formed sheets and fascic... | ['Animals', 'Female', 'Lymphoma', 'Mastocytoma, Skin', 'Rodent Diseases', 'Sciuridae'] | 19,139,521 | [['B01.050'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['C04.557.450.565.465.249.500', 'C04.557.450.565.465.500.500', 'C17.800.508.236.500', 'C17.800.508.473.500'], ['C22.795'], ['B01.050.150.900.649.313.992.750']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetics of oxaliplatin in patients with normal versus impaired renal function. | PURPOSE: The pharmacokinetics (PK) of platinum was investigated and compared in patients with normal (NRF) and impaired renal function (IRF), after they had received oxaliplatin at the recommended dose and delivery modality.METHODS: Oxaliplatin was administered at 130 mg/m(2) as a 2-h infusion without hydration. Patien... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Creatinine', 'Female', 'Humans', 'Infusions, Intravenous', 'Kidney Diseases', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Neoplasms', 'Organoplatinum Compounds', 'Oxaliplatin'] | 10,663,631 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['C12.777.419', 'C13.351.968.419'], ['E01.370.390.400'], ['M01.060.116.630'], ['C04'], ['D02.691.788'], ['D02.257.750']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Analysis of dementia patient mortality in a psychogeriatric unit]. | AIM: To determine the characteristics of patients with dementia who died in a psychogeriatric unit, and to describe the conditions that led to their death.MATERIAL AND METHODS: Observational study of patients who died in the Psychogeriatric unit of Hospital de la Santa Creu de Vic during a three and a half year period.... | ['Aged', 'Aged, 80 and over', 'Cause of Death', 'Dementia', 'Female', 'Geriatrics', 'Hospital Mortality', 'Hospital Units', 'Humans', 'Male', 'Psychiatry', 'Retrospective Studies'] | 23,122,479 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C10.228.140.380', 'F03.615.400'], ['H02.403.355'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Usefulness of iodine/creatinine ratio from spot-urine samples to evaluate the effectiveness of low-iodine diet preparation for radioiodine therapy. | OBJECTIVE: The success of a low-iodine diet (LID) is best determined by measurement of 24-h urine iodine (U-I) excretion. The aim of this study was to determine reliable estimates for 24-h U-I based on spot-urine samples and to provide cut-offs to determine the effectiveness of LID preparation.DESIGN: We prospectively ... | ['Adult', 'Creatinine', 'Diet', 'Female', 'Humans', 'Iodine', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Urinalysis'] | 20,050,860 | [['M01.060.116'], ['D03.383.129.308.207'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['M01.060.116.630'], ['E01.370.225.124.810', 'E01.370.390.810', 'E05.200.124.810']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of dietary exposure of 4-nonylphenol on growth and smoltification of juvenile coho salmon (Oncorhynchus kisutch). | There is considerable concern that endocrine disrupting substances such as 4-nonylphenol (4-NP) in the freshwater environment may have adverse effects on the growth, survival, and osmoregulatory ability of salmonids during and after their transfer to sea water. This study was conducted to examine the effects of dietary... | ['Animals', 'Diet', 'Endocrine Disruptors', 'Food Analysis', 'Gallbladder', 'Liver', 'Muscles', 'Oncorhynchus kisutch', 'Phenols', 'Thyroxine', 'Triiodothyronine', 'Water Pollutants, Chemical'] | 16,198,671 | [['B01.050'], ['G07.203.650.240'], ['D27.505.696.353', 'D27.888.141'], ['E05.362', 'J01.576.423.850.100'], ['A03.159.439'], ['A03.620'], ['A02.633', 'A10.690'], ['B01.050.150.900.493.817.750.705.580.410'], ['D02.455.426.559.389.657'], ['D06.472.931.812', 'D12.125.072.050.767'], ['D06.472.931.740.385', 'D12.125.072.050.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Estradiol is concentrated in tyrosine hydroxylase-containing neurons of the hypothalamus. | Localization of [3H]estradiol in tyrosine hydroxylase-containing neurons of rat brain was shown by a combined technique of autoradiography and immunohistochemistry. [3H]Estradiol was concentrated in the nuclei of tyrosine hydroxylase-containing neurons in the nucleus arcuatus, nucleus periventricularis hypothalami, and... | ['Animals', 'Arcuate Nucleus of Hypothalamus', 'Cell Nucleus', 'Estradiol', 'Female', 'Hypothalamus', 'Neurons', 'Paraventricular Hypothalamic Nucleus', 'Rats', 'Rats, Inbred Strains', 'Tyrosine 3-Monooxygenase'] | 6,141,639 | [['B01.050'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A08.675', 'A11.671'], ['A08.186.211.180.497.342.400', 'A08.186.211.200.317.3... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Y chromosome analysis of dingoes and southeast asian village dogs suggests a neolithic continental expansion from Southeast Asia followed by multiple Austronesian dispersals. | Dogs originated more than 14,000 BP, but the location(s) where they first arose is uncertain. The earliest archeological evidence of ancient dogs was discovered in Europe and the Middle East, some 5-7 millennia before that from Southeast Asia. However, mitochondrial DNA analyses suggest that most modern dogs derive fro... | ['Animals', 'Asia, Southeastern', 'Dogs', 'Haplotypes', 'Mutation', 'Polymorphism, Single Nucleotide', 'Tandem Repeat Sequences', 'Y Chromosome'] | 23,408,799 | [['B01.050'], ['Z01.252.145'], ['B01.050.150.900.649.313.750.250.216.200'], ['G05.380.360'], ['G05.365.590'], ['G05.365.795.598'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', 'G05.360.340.024.850'], ['A11.284.187.865.983', 'G05.360.162.865.983']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Massive lower gastrointestinal hemorrhage caused by a large extraluminal leiomyoma of the colon: report of a case. | The occurrence of leiomyoma of the colon is uncommon. Most of these lesions are clinically silent and are found incidentally during laparotomy or endoscopic procedures for unrelated conditions. Symptomatic leiomyomas of the colon are encountered less frequently, with only sporadic reports in the literatures. We describ... | ['Aged', 'Angiography', 'Colectomy', 'Colonic Neoplasms', 'Colonoscopy', 'Diagnosis, Differential', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Leiomyoma', 'Tomography, X-Ray Computed'] | 18,408,972 | [['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E04.210.219'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Periphyton bioconcentrates pesticides downstream of catchment dominated by agricultural land use. | Periphyton provides important ecosystem services in aquatic environments, including supporting diverse consumers. We studied pesticide bioconcentration in periphyton in a coastal marsh on Lake Erie. The marsh is within a protected area (Rondeau Provincial Park) but receives discharge from tributaries draining intensive... | ['Agriculture', 'Food Chain', 'Fungicides, Industrial', 'Herbicides', 'Periphyton', 'Pesticides', 'Water Pollutants, Chemical'] | 31,731,130 | [['J01.040'], ['G16.500.275.157.250', 'N06.230.124.250'], ['D27.720.031.700.288', 'D27.888.723.288'], ['D27.720.031.700.366', 'D27.888.723.366'], ['B05.080.250', 'G06.591.937', 'G16.500.275.157.049.100.500.937', 'N06.230.124.049.100.500.875'], ['D27.720.031.700', 'D27.888.723'], ['D27.888.284.903.655']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
On B1 inhomogeneity correction of in vivo human brain glutamate chemical exchange saturation transfer contrast at 7T. | The effects of radio frequency field (B(1)) inhomogeneity on measured in vivo human brain glutamate chemical exchange saturation transfer contrast maps are normally confounded with contributions from chemical exchange saturation transfer, direct saturation and magnetization transfer effects. Consequently, the chemical ... | ['Adult', 'Algorithms', 'Artifacts', 'Brain', 'Glutamic Acid', 'Humans', 'Magnetic Resonance Spectroscopy', 'Male', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 22,511,396 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E05.047'], ['A08.186.211'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Serum Markers Associated with Severity and Outcome of Hantavirus Pulmonary Syndrome. | BACKGROUND: Hantavirus pulmonary syndrome (HPS) is caused by Andes virus (ANDV) and related hantaviruses in the Americas. Despite a fatality rate of 40%, the pathogenesis of HPS is poorly understood and factors associated with severity, fatality, and survival remain elusive.METHODS: Ninety-three ANDV-infected HPS patie... | ['Adult', 'Biomarkers', 'Cytokines', 'Female', 'Hantavirus', 'Hantavirus Pulmonary Syndrome', 'Humans', 'Male', 'Retrospective Studies', 'Severity of Illness Index'] | 30,698,699 | [['M01.060.116'], ['D23.101'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B04.820.480.750.440'], ['C01.925.782.147.420.380', 'C08.618.846.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hydrogen uptake in Nostoc sp. strain PCC 73102. Cloning and characterization of a hupSL homologue. | Structural genes encoding an uptake hydrogenase of Nostoc sp. strain PCC 73102 were isolated. From partial libraries of genomic DNA, two clones (pNfo01 and pNfo02) were selected and sequenced, revealing the complete sequence of both a hupS (960 bases) and a hupL (1,593 bases) homologue in Nostoc sp. strain PCC 73102. A... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Blotting, Southern', 'Cloning, Molecular', 'Cyanobacteria', 'DNA Primers', 'DNA Probes', 'DNA, Bacterial', 'Genes, Bacterial', 'Hydrogen', 'Hydrogenase', 'Molecular Sequence Data', 'Nitrogen Fixation', 'Open Reading Frames', 'Sequence Alignment', 'Sequence... | 9,531,626 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['B03.280', 'B03.440.475.100'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.600.223', 'D27.505.259.75... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lung ultrasound in internal medicine efficiently drives the management of patients with heart failure and speeds up the discharge time. | Lung ultrasound (LUS) is a valid tool for the assessment of heart failure (HF) through the quantification of the B-lines. This study in HF patients aims to evaluate if LUS: (1) can accelerate the discharge time; (2) can efficiently drive diuretic therapy dosage; and (3) may have better performance compared to the amino... | ['Aged', 'Aged, 80 and over', 'Disease Management', 'Echocardiography', 'Female', 'Heart Failure', 'Humans', 'Italy', 'Length of Stay', 'Lung', 'Male', 'Patient Discharge', 'Regression Analysis', 'Statistics, Nonparametric', 'Time Factors', 'Ultrasonography'] | 28,803,375 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N04.590.607'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E02.760.400.480', 'N02.421.585.400.480'], ['A04.411'], ['E02.760.169.125', 'E02.760.400.610', 'N02.4... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Allele-specific and peptide-dependent recognition of swine leukocyte antigen class I by human cytotoxic T-cell clones. | BACKGROUND: The T-cell mediated immune responses play a major role in xenograft rejection. However, the mechanisms behind human T-cell recognition of porcine xenoantigens remain to be elucidated.METHODS: Human CD8+ T-cell lines were generated against porcine aortic endothelial cells (PAECs) from y/y and z/z haplotypes ... | ['Alleles', 'Animals', 'Antigens, Heterophile', 'Clone Cells', 'Genes, MHC Class I', 'Graft Rejection', 'Histocompatibility Antigens Class I', 'Humans', 'Peptides', 'Swine', 'T-Lymphocytes, Cytotoxic', 'Transfection', 'Transplantation, Heterologous'] | 10,480,402 | [['G05.360.340.024.340.030'], ['B01.050'], ['D23.050.244'], ['A11.251.353'], ['G05.360.340.024.340.610.595', 'G05.360.340.024.380.500.595', 'G12.500.500.595'], ['G12.875.545.328'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.301.500.100', 'D23.050.705.552.100'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An ELISA method for the quantitation of tracheal mucins from human and nonhuman primates. | Monoclonal antibodies, 17B1 and 17Q2, which are specific for large molecular weight mucous glycoproteins of airway epithelium, have been used to develop an ELISA method to quantitate the tracheal mucins of humans and rhesus monkeys. The assay is a double-sandwich system that does not depend on either the binding of muc... | ['Amino Acids', 'Animals', 'Antibodies, Monoclonal', 'Carbohydrates', 'Chromatography, Gel', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Mucins', 'Mucous Membrane', 'Primates', 'Proteoglycans', 'Sputum', 'Trachea'] | 2,624,758 | [['D12.125'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D09'], ['E05.196.181.400.250'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in body composition and muscle protein degradation during nutritional supplementation in nutritionally growth-retarded children with cystic fibrosis. | Changes in body composition and muscle protein degradation were studied in seven nutritionally growth-retarded children with cystic fibrosis (CF) before and after nutritional supplementation and in eight healthy children who served as controls. Supplemental feedings consisted of a peptide formula that increased dietary... | ['Adolescent', 'Body Composition', 'Body Weight', 'Child', 'Child, Preschool', 'Cystic Fibrosis', 'Dietary Proteins', 'Energy Intake', 'Female', 'Food, Fortified', 'Growth Disorders', 'Humans', 'Male', 'Methylhistidines', 'Muscle Proteins'] | 6,620,051 | [['M01.060.057'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['M01.060.406.448'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D12.776.256', 'G07.203.300.428', 'J02.50... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Effects of mesenteric vein L-alanine infusion on liver metabolism of organic acids by beef heifers fed diets differing in forage: concentrate ratio. | Effects of diet forage:concentrate ratio and mesenteric vein L-alanine infusion on net VFA metabolism by portal-drained viscera (PDV) and liver were determined in four multicatheterized Hereford x Angus heifers (443 kg BW) fed in equal meals every 2 h pelleted, isonitrogenous diets containing 75% alfalfa or 75% corn:so... | ['Alanine', 'Amino Acids', 'Animal Feed', 'Animals', 'Cattle', 'Digestive System', 'Fatty Acids, Volatile', 'Female', 'Glucose', 'Infusions, Intravenous', 'Liver', 'Mesenteric Veins', 'Pancreas', 'Regional Blood Flow', 'Soybeans', 'Spleen', 'Urea', 'Zea mays'] | 7,759,370 | [['D12.125.042'], ['D12.125'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A03'], ['D10.251.400'], ['D09.947.875.359.448'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['A03.620'], ['A07.015.908.670.385'], ['A03.734'], ['G09.330.100.780'], ['B01.650.940.800.57... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fetal cranial and craniocervical masses: ultrasound characteristics and differential diagnosis. | Ultrasound is assuming an essential role in the detection of fetal cranial and spinal anomalies. Illustrated in this article is the sonographic appearance of cranial abnormalities wherein the diagnosis of encephalocele is clear cut because the anatomic defect of the neural tube is visualized. Additionally presented is ... | ['Adult', 'Female', 'Fetal Death', 'Fetal Diseases', 'Humans', 'Neural Tube Defects', 'Pregnancy', 'Ultrasonography'] | 7,425,015 | [['M01.060.116'], ['C13.703.223', 'C23.550.260.585'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.500.680', 'C16.131.666.680'], ['G08.686.784.769'], ['E01.370.350.850']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Promoting wellness in individuals with coronary heart disease. | The care of patients with coronary heart disease is focused toward assisting each individual to maximize his or her level of wellness by understanding and adhering to the prescribed medical regimen as a means for reducing or eliminating modifiable cardiovascular risk factors. Despite the role of risk modification in th... | ['Coronary Disease', 'Health Behavior', 'Health Promotion', 'Humans', 'Models, Psychological', 'Motivation', 'Risk Factors'] | 9,095,452 | [['C14.280.647.250', 'C14.907.585.250'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F01.658', 'F01.752.543.500.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.52... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Bilateral vas deferens agenesis and inguinal hernia in a child. A rare, early presentation of cystic fibrosis]. | UNLABELLED: Epididymal and ductal anomalies can be discovered incidentally during inguinal herniorraphy in children. The congenital bilateral absence of vas deferens is frequently associated with cystic fibrosis.CASE REPORT: This agenesia of vas deferens was detected in a 5-month-old boy who underwent an inguinal herni... | ['Cystic Fibrosis', 'Diagnosis, Differential', 'Hernia, Inguinal', 'Humans', 'Infant', 'Male', 'Oligospermia', 'Vas Deferens'] | 11,484,456 | [['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['E01.171'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C12.294.365.700.508'], ['A05.360.444.930']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nutritional management of idiopathic chronic colitis in the dog. | Idiopathic chronic colitis was diagnosed in 13 dogs. Owners sought veterinary care because of semiformed to liquid feces, fresh blood and/or mucus in the feces, tenesmus, increased frequency of defecation, vomiting, weight loss, and flatulence in their dogs. A lymphocytic, plasmacytic infiltration in the colonic lamina... | ['Animals', 'Colitis', 'Diarrhea', 'Dog Diseases', 'Dogs', 'Female', 'Male'] | 3,225,807 | [['B01.050'], ['C06.405.205.265', 'C06.405.469.158.188'], ['C23.888.821.214'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Promotion of physical activity using point-of-decision prompts in Berlin underground stations. | To evaluate point-of-decision prompts in the promotion of stair use in Germany, motivational posters were placed at three underground stations in Berlin. The proportion of passengers using stairs or stairways was counted before, during installation, and two weeks after removal of posters. In total, 5,467 passersby were... | ['Berlin', 'Exercise', 'Female', 'Health Promotion', 'Humans', 'Male', 'Sex Characteristics', 'Transportation'] | 20,948,947 | [['Z01.433.128', 'Z01.542.315.182'], ['G11.427.410.698.277', 'I03.350'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.815'], ['J01.937']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
[Biological adaptation of children of preschool age with retardation of mental development (RMD) in conditions of pre-school correctional educational institutions]. | The present study was devoted to the investigation of biological adaptation of children aged 6-7 years with retardation of mental development (RMD) in pre-school correctional educational institutions. Under supervision there were 69 children, out of them 34 RMD cases and 35 children in whom mental development correspon... | ['Adaptation, Physiological', 'Case-Control Studies', 'Child', 'Female', 'Heart Rate', 'Humans', 'Intellectual Disability', 'Male', 'Russia', 'Schools', 'Sympathetic Nervous System'] | 24,003,703 | [['G07.025', 'G16.012.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['Z01.252.122.500', 'Z01.542... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
What is the value of ITS sequence data in Colletotrichum systematics and species diagnosis? A case study using the falcate-spored graminicolous Colletotrichum group. | Because the genus Colletotrichum is among the most important groups of plant pathogenic fungi worldwide, the ability to accurately diagnose species is vital for the implementation of effective disease control and quarantine measures. Although the long-standing, unresolved taxonomic issues in the genus have recently beg... | ['Colletotrichum', 'Computational Biology', 'DNA, Fungal', 'DNA, Ribosomal Spacer', 'Databases, Genetic', 'Mycological Typing Techniques', 'Poaceae', 'Sequence Analysis, DNA', 'Species Specificity'] | 19,750,944 | [['B01.300.381.235'], ['H01.158.273.180', 'L01.313.124'], ['D13.444.308.300'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E01.370.225.875.610', 'E05.200.875.610'], ['B01.650.940.800.575.912.250.822'], ['E05.393.760.700'], ['G16.824']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Intracerebral haemorrhage complicating dural arteriovenous fistula: a report of two cases. | Two patients presented with unilateral peri-orbital pain, proptosis, chemosis and external ophthalmoplegia. They were shown to have dural arteriovenous fistulae related to the cavernous sinus. Intracerebral haemorrhage occurred in both patients within 18 months of presentation; this gave rise to focal seizures and sign... | ['Aged', 'Cavernous Sinus', 'Cerebral Angiography', 'Cerebral Hemorrhage', 'Dura Mater', 'Embolization, Therapeutic', 'Exophthalmos', 'Female', 'Humans', 'Intracranial Arteriovenous Malformations', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Ophthalmoplegia', 'Recurrence', 'Tomography, X-Ray Computed', 'Visual Fiel... | 6,481,384 | [['M01.060.116.100'], ['A07.015.908.224.334'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['A08.186.566.395'], ['E02.520.360', 'E02.926.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The prevalence of alpha-antitrypsin heterozygotes (Pi MZ) in patients with obstructive pulmonary disease. | An increased incidence of intermediate deficiency of serum alpha1-antitrypsin resulting from Pi phenotype MZ has been reported in patients with chronic obstructive pulmonary disease (COPD) by some laboratories but not confirmed by others. Prevalence of Pi MZ was determined in patients with COPD among 502 subjects refer... | ['Adult', 'Female', 'Heterozygote', 'Humans', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Phenotype', 'Respiratory Function Tests', 'Smoking', 'alpha 1-Antitrypsin', 'alpha 1-Antitrypsin Deficiency'] | 1,087,539 | [['M01.060.116'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495'], ['M01.060.116.630'], ['G05.695'], ['E01.370.386.700'], ['F01.145.805'], ['D12.644.861.035', 'D12.776.124.050.070', 'D12.776.124.790.106.085', 'D12.776.377.715.085.085', 'D12.776.395.068', 'D12.776.872.035'], ['C06.552.0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[D-Pen2,4'-125I-Phe4,D-Pen5]enkephalin: a selective high affinity radioligand for delta opioid receptors with exceptional specific activity. | [D-Pen2,4'-125I-Phe4,D-Pen5]enkephalin ([125I]DPDPE) is a highly selective radioligand for the delta opioid receptor with a specific activity (2200 Ci/mmol) that is over 50-fold greater than that of tritium-labeled DPDPE analogs. [125I]DPDPE binds to a single site in rat brain membranes with an equilibrium dissociation... | ['Animals', 'Autoradiography', 'Brain', 'Cerebral Cortex', 'Corpus Striatum', 'Enkephalins', 'Iodine Radioisotopes', 'Kinetics', 'Ligands', 'Male', 'Olfactory Bulb', 'Rats', 'Rats, Inbred Strains', 'Receptors, Opioid', 'Receptors, Opioid, delta'] | 1,653,834 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['A08.186.211.200.885.287.249.487'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['G01.374.661', 'G02.111.490'], ['D27.720... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of ritonavir in plasma/serum and tissues by high-performance liquid chromatography. | A method has been developed to quantify ritonavir concentrations in human plasma and in mouse serum, liver, and brain using high-performance liquid chromatography. Extraction recoveries for ritonavir and its internal standard averaged greater than 95%. Within-day variability, expressed as a coefficient of variation, av... | ['Animals', 'Brain Chemistry', 'Calibration', 'Chemistry, Pharmaceutical', 'Chromatography, High Pressure Liquid', 'Humans', 'Liver', 'Mice', 'Reproducibility of Results', 'Ritonavir'] | 10,465,159 | [['B01.050'], ['G02.111.150', 'G03.185'], ['E05.978.155'], ['H01.158.703.007', 'H01.181.466'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['D02.886.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Attitudes of the Lebanese public regarding disclosure of serious illness. | OBJECTIVES: To measure the preference regarding disclosure of a serious diagnosis, and its determinants, of the Lebanese public.DESIGN AND SETTING: Non-random sample survey of 400 persons interviewed in health care facilities in Beirut in 1995.RESULTS: Forty-two per cent of respondents generally preferred truth not to ... | ['Adult', 'Attitude of Health Personnel', 'Attitude to Health', 'Educational Status', 'Female', 'Health Status', 'Humans', 'Islam', 'Lebanon', 'Male', 'Physician-Patient Relations', 'Truth Disclosure'] | 10,536,765 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['F01.100.150', 'N05.300.150'], ['N01.824.196'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.844.275'], ['Z01.252.245.500.450'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F01.829.401.046.800', 'I01.88... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mismatches in the Influenza A Virus RNA Panhandle Prevent Retinoic Acid-Inducible Gene I (RIG-I) Sensing by Impairing RNA/RIG-I Complex Formation. | Influenza virus RNA (vRNA) promoter panhandle structures are believed to be sensed by retinoic acid-inducible gene I (RIG-I). The occurrence of mismatches in this double-stranded RNA structure raises questions about their effect on innate sensing. Our results suggest that mismatches in vRNA promoters decrease binding t... | ['Base Pair Mismatch', 'Cell Line', 'DEAD Box Protein 58', 'DEAD-box RNA Helicases', 'Epithelial Cells', 'Host-Pathogen Interactions', 'Humans', 'Immune Evasion', 'Immunity, Innate', 'Influenza A virus', 'Nucleic Acid Conformation', 'Protein Binding', 'RNA, Double-Stranded', 'RNA, Viral', 'RNA-Binding Proteins'] | 26,446,607 | [['G05.365.590.060'], ['A11.251.210'], ['D08.811.913.696.445.735.720.249.750'], ['D08.811.913.696.445.735.720.249'], ['A11.436'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.462.400', 'G12.413', 'G16.527.200.700'], ['G12.450.564'], ['B04.820.480.968.405.400'], ['G02.111.570.820.48... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of short-term exercise training on angiogenic growth factor gene responses in rats. | We investigated whether 1) 5 days of exercise training would reduce the acute exercise-induced increase in skeletal muscle growth factor gene expression; and 2) reductions in the increase in growth factor gene expression in response to short-term exercise training would be coincident with increases in skeletal muscle o... | ['Animals', 'Citrate (si)-Synthase', 'Endothelial Growth Factors', 'Female', 'Fibroblast Growth Factors', 'Gene Expression Regulation', 'Lymphokines', 'Oxidation-Reduction', 'Physical Conditioning, Animal', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Transforming Growth Factor beta', 'Vascular Endothelial Growth Factor ... | 11,247,917 | [['B01.050'], ['D08.811.913.050.368'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['G05.308'], ['D12.644.276.374.480', 'D12.776.467.374.480', 'D23.529.374.480'], ['G02.700', 'G03.295.531'], ['G11.427.410.698.277.280'], ['D13.444.735.544'], ['B01.050.150... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Occupational metal poisoning (author's transl)]. | The early diagnosis of lead poisoning -- the most common type of occupational metal poisoning -- based on the determination of the haemprecursors coproporphyrin, delta amino laevulinic acid and free erythrocyte protoporphyrin. Treatment with chelating agents increases urinary lead excretion very effectively. Clinical m... | ['Cadmium Poisoning', 'Chromium', 'Humans', 'Lead Poisoning', 'Mercury Poisoning', 'Metals', 'Occupational Diseases'] | 223,335 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral function and nutritional status among the elderly with facial and oral tactile hypersensitivity who are under long-term care. | Objective?In oral health care, a refusal action can cause difficulties, and tactile hypersensitivity (TH) may be a contributing factor. People with TH of the face and mouth clench their jaws. Despite numerous reports on TH among children with disabilities, reports on TH in the elderly who are under long-term care are s... | ['Aged, 80 and over', 'Female', 'Humans', 'Hypersensitivity', 'Long-Term Care', 'Male', 'Nutritional Status', 'Oral Health', 'Touch'] | 28,966,290 | [['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E02.760.476', 'N02.421.585.476'], ['G07.203.650.650', 'N01.224.425.525'], ['N01.400.535'], ['F02.830.816.850', 'G11.561.790.850']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incorporation of Sed1p into the cell wall of Saccharomyces cerevisiae involves KRE6. | KRE6 (YPR159W) encodes a Golgi membrane protein required for normal beta-1,6-glucan levels in the cell wall. A functional Kre6p is necessary for cell wall protein accumulation in response to changing metabolic conditions. The product of the SED1 (YDR077W) gene is a stress-induced GPI-cell wall protein. Successful incor... | ['Amino Acid Sequence', 'Base Sequence', 'Cell Wall', 'DNA, Fungal', 'Genes, Fungal', 'Glycosylphosphatidylinositols', 'Membrane Glycoproteins', 'Membrane Proteins', 'Molecular Sequence Data', 'Mutation', 'Phenotype', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 15,093,776 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.183'], ['D13.444.308.300'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D09.400.410.475', 'D10.390.475', 'D10.570.755.375.760.400.942.250'], ['D12.776.395.550', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anxiety, Family Functioning and Neuroendocrine Biomarkers in Obese Children. | INTRODUCTION: This observational study explores potential links between obese children's cortisol, and parental mental state, family functioning, and the children's symptoms of anxiety and depression.MATERIAL AND METHODS: A non-random sample of 104 obese children (55 boys), mean age 10.9 years (standard deviation 1.76)... | ['Anxiety', 'Biomarkers', 'Child', 'Family Relations', 'Female', 'Hormones', 'Humans', 'Male', 'Pediatric Obesity'] | 28,555,552 | [['F01.470.132'], ['D23.101'], ['M01.060.406'], ['F01.829.263.370', 'I01.880.853.150.439'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500.720', 'C23.888.144.699.500.750', 'E01.370.600.115.100.160.120.699.500.750', 'G07.100.100.160.120.699.500.750']] | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Lack of infectivity of a Brazilian Anaplasma marginale isolate for Boophilus microplus ticks. | Previous studies have shown that one Brazilian Anaplasma marginale isolate presents an inclusion appendage (tail), while other isolates do not present such inclusion. Studies on tick transmission have been carried out with tailless isolates but little is known about transmission of tailed isolates by Boophilus microplu... | ['Anaplasma marginale', 'Anaplasmosis', 'Animals', 'Brazil', 'Cattle', 'Cattle Diseases', 'Digestive System', 'Erythrocytes', 'Female', 'Hematocrit', 'Infectious Disease Transmission, Vertical', 'Ixodidae', 'Male', 'Salivary Glands'] | 15,740,870 | [['B03.440.664.750.050.500', 'B03.660.050.783.500.050.500'], ['C01.150.252.400.054.500', 'C01.150.252.400.082', 'C01.920.930.163', 'C22.085'], ['B01.050'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A03'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.225.625.400', 'E05.... | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A deflection system to reduce the interference from post-source decay product ions in photodissociation tandem time-of-flight mass spectrometry. | A deflection system consisting of four deflectors was designed and used to reduce the interference from post-source decay (PSD) product ions in photodissociation (PD) tandem time-of-flight (TOF) mass spectrometry. For simple protonated peptides generated by matrix-assisted laser desorption/ionization, the presence of P... | ['Peptide Mapping', 'Peptides', 'Photochemistry', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Tandem Mass Spectrometry'] | 16,791,872 | [['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['D12.644'], ['H01.181.529.711'], ['E05.196.566.755'], ['E05.196.566.880']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Patient selection issues in peritoneal dialysis. | Advances in peritoneal dialysis (PD) technology and better understanding of peritoneal solute transport have expanded the application of this therapy to a larger segment of the end-stage renal disease (ESRD) community. However, adequate patient selection remains an important issue in assuring success of this therapy. M... | ['Algorithms', 'Humans', 'Patient Selection', 'Peritoneal Dialysis'] | 9,360,656 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500.653', 'N04.590.731'], ['E02.870.300.650', 'E02.912.800.650']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A comparison of some biologic characteristics of isolates of the Legionnaires' disease bacterium. | The ability of three isolates of serogroup 1 and one isolate of serogroup 4 of Legionnaires' disease bacterium (LDB) to infect and cause fever and death in guinea pigs was studied, as well as their ability to produce plaques in cultured primary chick embryo cells. The serogroup 4 isolate originally was recovered from c... | ['Animals', 'Chick Embryo', 'Fatty Acids', 'Female', 'Guinea Pigs', 'Humans', 'Legionella', 'Pregnancy'] | 7,212,630 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['D10.251'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.400.425.450.450', 'B03.660.250.460.460'], ['G08.686.784.769']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Problem of HIV-infected patients receiving dialysis]. | According to UNAIDS data there are 40 millions of HIV infected people in the world. 7880 people are infected with HIV (official statistics) in Poland. Because of improvement of dialysis accessibility in Poland there is no limitations of qualification for dialysis for HIV infected patients. In this article authors prese... | ['AIDS-Associated Nephropathy', 'Algorithms', 'Decision Trees', 'HIV Infections', 'HIV Seropositivity', 'Humans', 'Kidney Failure, Chronic', 'Poland', 'Renal Dialysis', 'Risk Factors'] | 15,518,330 | [['C01.221.250.875.050', 'C01.221.812.640.400.072', 'C01.778.640.400.072', 'C01.925.782.815.616.400.050', 'C01.925.813.400.072', 'C12.777.419.050', 'C13.351.968.419.050', 'C20.673.480.050'], ['G17.035', 'L01.224.050'], ['G17.162.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.4... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Evaluation of the measurement properties of the Manchester foot pain and disability index. | BACKGROUND: The Manchester Foot Pain and Disability Index (MFPDI, 19 items) was developed to measure functional limitations, pain and appearance for patients with foot pain and is frequently used in both observational studies and randomised controlled trials. A Dutch version of the MFPDI was developed. The aims of this... | ['Aged', 'Biomechanical Phenomena', 'Cultural Characteristics', 'Disability Evaluation', 'England', 'Factor Analysis, Statistical', 'Female', 'Foot', 'Humans', 'Interdisciplinary Communication', 'Male', 'Middle Aged', 'Musculoskeletal Pain', 'Netherlands', 'Pain Measurement', 'Pain Perception', 'Predictive Value of Tes... | 25,115,354 | [['M01.060.116.100'], ['G01.154.090', 'G01.374.089'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['E01.370.400'], ['Z01.542.363.300'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', ... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts. | The influence of ciprofloxacin, nalidixic acid, norfloxacin, novobiocin, and ofloxacin on elements of eucaryotic DNA replication was investigated in vitro. Each of the 4-quinolones, when present in amounts of more than 100 micrograms/ml, reversibly inhibited the DNA synthesis performed by the 95 DNA polymerase alpha pr... | ['Cell Division', 'Cell Line', 'Ciprofloxacin', 'DNA Polymerase II', 'DNA Topoisomerases, Type I', 'DNA, Bacterial', 'Electrophoresis, Agar Gel', 'Humans', 'Lymphocytes', 'Novobiocin', 'Ofloxacin', 'Oxazines', 'Quinolines', 'Spheroplasts', 'Thymus Gland'] | 3,015,015 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D03.633.100.810.835.322.186'], ['D08.811.913.696.445.308.300.230'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['D13.444.308.212'], ['E05.196.401.153', 'E05.301.300.100'], ['B01.050.150.900.649.313.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical effect of intravenous ciprofloxacin on hospital-acquired pneumonia. | The effect of intravenous ciprofloxacin (CPFX) on hospital-acquired pneumonia was examined. The subjects were 32 patients with hospital-acquired pneumonia classified as being in group I, group II, and group III, based on The Japanese Respiratory Society Guidelines for management of hospital-acquired pneumonia. None of ... | ['Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Ciprofloxacin', 'Cross Infection', 'Drug Resistance, Bacterial', 'Female', 'Gram-Negative Bacteria', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacteria', 'Gram-Positive Bacterial Infections', 'Humans', 'Infection Control', 'Infusions, Intravenous', 'Mal... | 15,729,490 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['D03.633.100.810.835.322.186'], ['C01.248', 'C23.550.291.875.500'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B03.440'], ['C01.150.252.400'], ['B03.510'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional substance P receptors on a rat pancreatic acinar cell line. | A pancreatic acinar cell line, AR4-2J, that expresses a high density of substance P (SP)-binding sites has been identified. SP-binding sites on intact AR4-2J cells were detected with 125I-Bolton-Hunter SP (125I-BHSP). 125I-BHSP binding to AR4-2J cells has an apparent Kd of 40 pm with slow rates of association and disso... | ['Amylases', 'Animals', 'Calcium', 'Cell Line', 'Electrophysiology', 'Iodine Radioisotopes', 'Pancreas', 'Rats', 'Receptors, Neurokinin-1', 'Receptors, Neurotransmitter', 'Substance P', 'Succinimides', 'Time Factors'] | 2,416,893 | [['D08.811.277.450.066'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['H01.158.344.528', 'H01.158.782.236'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['A03.734'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.695.862.500', 'D12.776.543... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of PKC-è preserves cardiac function and reduces fibrosis in streptozotocin-induced diabetic cardiomyopathy. | BACKGROUND AND PURPOSE: T-cell infiltration, interstitial fibrosis and cardiac dysfunction have been observed in diabetic patients with cardiovascular diseases. PKC-è is crucial for the activation of mature T-cells. We hypothesized that inhibition of PKC-è might protect diabetic hearts through inhibition of T-cell stim... | ['Animals', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 1', 'Fibrosis', 'Heart', 'Homeodomain Proteins', 'Isoenzymes', 'Male', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Myocardial Contraction', 'Myocardium', 'Protein Kinase C', 'Protein Kinase C-theta', 'Protein Kinase Inhibitors', 'T-Lymphocytes', 'Zonu... | 24,641,494 | [['B01.050'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C23.550.355'], ['A07.541'], ['D12.776.260.400'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decreasing trend in passive tobacco smoke exposure and association with asthma in U.S. children. | In this study, we assessed trends of serum cotinine levels over time among US children ages 3-11 years and compared the risk of asthma in groups exposed to passive tobacco smoke. We utilized National Health and Nutrition Examination Survey (NHANES) data collected from 2003 to 2014 (n = 8064). Serum cotinine level, hous... | ['Asthma', 'Child', 'Child, Preschool', 'Cotinine', 'Family Characteristics', 'Humans', 'Nutrition Surveys', 'Tobacco Smoke Pollution', 'United States'] | 29,859,939 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['D03.383.773.812.180'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.485... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes. | Determination of specific GTPase (EC 3.6.1.--) activity in turkey erythrocyte membranes was achieved using low concentration of GTP (0.25 muM), inhibition of nonspecific nucleoside triphosphatases by adenosine 5'(beta,gamma-imino-triphosphate (App(NH)p) and suppression of the transfer of gamma-32P from GTP to ADP with ... | ['Adenylyl Cyclases', 'Animals', 'Catecholamines', 'Catechols', 'Dopamine', 'Enzyme Activation', 'Epinephrine', 'Erythrocyte Membrane', 'Erythrocytes', 'GTP Phosphohydrolases', 'Isoproterenol', 'Kinetics', 'Norepinephrine', 'Phenylephrine', 'Phosphoric Monoester Hydrolases', 'Propranolol', 'Turkeys'] | 188,466 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D02.455.426.559.389.657.166'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G02.111.263', 'G03.328'], ['D02.033.100.291.310', 'D02.092.063.291.310', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of the UPR protects against cigarette smoke-induced RPE apoptosis through up-regulation of Nrf2. | Recent studies have revealed a role of endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) in the regulation of RPE cell activity and survival. Herein, we examined the mechanisms by which the UPR modulates apoptotic signaling in human RPE cells challenged with cigarette smoking extract (CSE). Our ... | ['Acetylcysteine', 'Apoptosis', 'Blotting, Western', 'Cell Line', 'Cell Survival', 'DNA-Binding Proteins', 'Endoplasmic Reticulum Stress', 'Epithelial Cells', 'Free Radical Scavengers', 'Gene Expression', 'Humans', 'Methylamines', 'Mitochondria', 'NF-E2-Related Factor 2', 'RNA Interference', 'Reactive Oxygen Species', ... | 25,568,320 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['G04.346'], ['D12.776.260'], ['G04.434'], ['A11.436'], ['D27.505.519.217.500'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of stenting after rotational atherectomy for ostial LAD and ostial LCX stenosis in patients with diabetes. | OBJECTIVE: The goal of this study was to investigate the efficacy of stenting after rotational atherectomy (rotastent) for ostial LAD and ostial LCX stenosis in patients with diabetes.BACKGROUND: Previous studies have demonstrated that rotastent for non-aorto ostial stenoses can be performed safely with high clinical s... | ['Aged', 'Atherectomy, Coronary', 'Blood Vessel Prosthesis Implantation', 'Coronary Angiography', 'Coronary Stenosis', 'Diabetes Complications', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Reoperation', 'Stents', 'Treatment Outcome'] | 15,640,533 | [['M01.060.116.100'], ['E02.148.050.120.125', 'E04.100.376.719.125', 'E04.100.814.529.124.120.125', 'E04.100.814.529.968.060', 'E04.502.382.124.120.125', 'E04.502.382.968.060', 'E04.928.220.520.110', 'E05.157.016.120.125'], ['E04.100.814.868.500', 'E04.650.200'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of danazol on the production of C1 inhibitor in the guinea pig. | The production of C1 inhibitor (C1-INH) in guinea pig liver was studied following administration of danazol. Immunochemical assays of the inhibitor were performed on serial serum specimens. An increase in serum C1-INH was observed following danazol treatment. Immunohistochemical studies confirmed that the liver is the ... | ['Animals', 'Complement C1 Inactivator Proteins', 'Danazol', 'Female', 'Guinea Pigs', 'Immunoenzyme Techniques', 'Liver', 'Microscopy, Electron', 'Molecular Weight', 'Pregnadienes'] | 6,399,878 | [['B01.050'], ['D12.644.861.140', 'D12.776.124.486.274.920.250', 'D12.776.872.140'], ['D04.210.500.745.432.235'], ['B01.050.150.900.649.313.992.550'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A03.620'], ['E01.370.350.515.402', 'E05.595.402'], ['G02.494'], ['D04.210.500.745.432']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigator® Argus X-12 study on the population of Czech Republic: comparison of linked and unlinked X-STRs for kinship analysis. | DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator® Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146... | ['Chromosomes, Human, X', 'Czech Republic', 'European Continental Ancestry Group', 'Female', 'Genetic Markers', 'Genetics, Population', 'Genotyping Techniques', 'Humans', 'Linkage Disequilibrium', 'Male', 'Microsatellite Repeats'] | 24,789,012 | [['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['Z01.542.248.395'], ['M01.686.508.400'], ['D23.101.387', 'G05.695.450'], ['H01.158.273.343.335'], ['E05.393.442'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.500'], ['G02.111.570.080.7... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
Angiographic and clinical characteristics associated with the removable plaque components by means of thrombectomy catheters in patients with myocardial infarction. | BACKGROUND: Previous studies have demonstrated that atheroembolism during percutaneous coronary intervention is associated with myocardial damage. The purpose of this study is to investigate the clinical and angiographic characteristics related to removable plaque elements in patients undergoing thrombectomy for myocar... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Cardiac Catheterization', 'Coronary Angiography', 'Coronary Thrombosis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Risk Factors', 'Stents', 'Thrombectomy', 'Thrombolytic Therapy', 'Treatment Outcome'] | 18,053,944 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.625', 'E01.370.350.700.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A normative study of a shorter version of Raven's progressive matrices 1938. | A shorter four-set (A, B, C, D) version of Raven's progressive matrices 1938 (PM38) has gained increasing use in neuropsychological assessment. No normative data spanning across a wide age range are, however, available. This study collected norms for the shorter version of PM38, established an inferential cut-off value... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Brain Damage, Chronic', 'Educational Status', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Predictive Value of Tests', 'Reference Values', 'Regression Analysis', 'Reproducibility of Results', 'Sex Factors'] | 14,716,529 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.140'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['F04.711.513'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.65... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of dietary calcium to available phosphorus ratios on bone metabolism and osteoclast activity of the OPG /RANK/RANKL signalling pathway in piglets. | Hydroxyapatite, a mineral form of calcium (Ca) and phosphorus (P) that gives bones their rigidity, is the major and essential component of bones and teeth in the human and animal body. A suitable ratio of Ca and P is vital for bone growth. The aim of this study was to explore the effects of dietary calcium to available... | ['Animals', 'Bone Density', 'Bone and Bones', 'Calcium, Dietary', 'Gene Expression Regulation', 'Male', 'Osteoclasts', 'Osteoprotegerin', 'Phosphorus, Dietary', 'RANK Ligand', 'Receptor Activator of Nuclear Factor-kappa B', 'Swine'] | 31,062,421 | [['B01.050'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['D01.146.395'], ['G05.308'], ['A11.329.372.700', 'A11.627.482.700'], ['D12.776.543.750.705.852.760.949.249'], ['D01.695.635'], ['D12.644.276.374.750.562', 'D12.776.467.374.750.562', 'D23.529.374.750.562'], ['D12.776.543.750.705.852.760.345'], ['B01.050.150... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Landscape surrounding human settlements and Anopheles albimanus (Diptera: Culicidae) abundance in Southern Chiapas, Mexico. | Landscape characteristics that may influence important components of the Anopheles albimanus Wiedemann life cycle, including potential breeding sites, suitable diurnal resting sites, and possible sources of blood meals, were analyzed at 14 villages in a malarious area of southern Mexico. An. albimanus adults were colle... | ['Animals', 'Anopheles', 'Environment', 'Humans', 'Mexico', 'Population Density'] | 8,906,903 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['N01.224.600', 'N06.850.505.400.600']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Immunization with Ascaris suum extract impairs T cell functions in mice. | The effect of an Ascaris suum extract (Asc) on several T cell functions was studied in mice immunized with Asc and ovalbumin (OA) in complete Freund's adjuvant. Delayed-type hypersensitivity reactions following challenge with aggregated OA were markedly diminished in mice injected with OA plus a high dose of Asc compar... | ['Animals', 'Antibodies, Helminth', 'Antibody Formation', 'Antigens, Helminth', 'Ascaris suum', 'Dose-Response Relationship, Immunologic', 'Hypersensitivity', 'Hypersensitivity, Delayed', 'Immunoglobulin Isotypes', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-2', 'Interleukin-4', 'Lymphocyte Activation', 'Male', ... | 7,743,547 | [['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['G12.450.050.370.250'], ['D23.050.223'], ['B01.050.500.500.294.400.500.100.108.700'], ['G12.300'], ['C20.543'], ['C20.543.418'], ['D12.776.124.486.485.114.619', 'D12.776.124.790.651.114.619', 'D12.776.377.715.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of MicroRNA-96 Ameliorates Cognitive Impairment and Inactivation Autophagy Following Chronic Cerebral Hypoperfusion in the Rat. | BACKGROUND/AIMS: Chronic cerebral hypoperfusion (CCH) is a high-risk factor for vascular dementia and Alzheimer's disease. Autophagy plays a critical role in the initiation and progression of CCH. However, the underlying mechanisms remain unclear. In this study, we identified the effect of a microRNA (miR) on autophagy... | ["3' Untranslated Regions", 'Alzheimer Disease', 'Animals', 'Antagomirs', 'Autophagosomes', 'Autophagy', 'Beclin-1', 'Binding Sites', 'Brain Ischemia', 'Cells, Cultured', 'Disease Models, Animal', 'Male', 'Maze Learning', 'Memory', 'MicroRNAs', 'Microtubule-Associated Proteins', 'Neurons', 'Rats', 'Rats, Sprague-Dawley... | 30,134,226 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['D13.695.578.424.112'], ['A11.284.430.214.190.875.190.700.500'], ['G04.011'], ['D12.644.360.075.335', 'D12.776.094.500',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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