Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system. | The pharmacology of the spinal and peripheral adrenergic receptor-subtypes controlling the micturition reflex was studied in a chronic unanesthetized rat model by continuous infusion of saline in the bladder and cystometrography after intrathecal (i.t.) and i.p. injections, respectively. Due to the absence of a cathete... | ['Animals', 'Isoproterenol', 'Methoxamine', 'Muscle Contraction', 'Muscle Relaxation', 'Norepinephrine', 'Peripheral Nerves', 'Phentolamine', 'Propranolol', 'Rabbits', 'Spinal Cord', 'Terbutaline', 'Urinary Bladder', 'Urination', 'Yohimbine'] | 3,367,300 | [['B01.050'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['D02.033.100.624.536', 'D02.033.755.624.536', 'D02.092.063.624.536', 'D02.092.471.683.661'], ['G11.427.494'], ['G11.427.494.554'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preoperative serum angiopoietin-2 levels correlate with lymph node status in patients with early gastric cancer. | BACKGROUND: Lymph node metastasis is the most important factor to consider when deciding on the modality of resection in patients with early gastric cancer. The aim of the present study was to assess the relationship between preoperative serum angiopoietin-2, a lymphangiogenic growth factor, and lymph node metastasis i... | ['Adenocarcinoma', 'Aged', 'Angiopoietin-2', 'Biomarkers, Tumor', 'Female', 'Humans', 'Lymph Nodes', 'Lymphatic Metastasis', 'Lymphatic Vessels', 'Male', 'Middle Aged', 'Stomach Neoplasms'] | 19,408,052 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['D23.101.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.650.560'], ['A15.382.520.301'], ['M01.060.116.630'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Central manipulation of dopamine receptors attenuates the orexigenic action of ghrelin. | OBJECTIVE: Recent evidence suggests that ghrelin, a peptidic hormone stimulating food intake, interacts with the dopamine signaling. This interaction has been demonstrated to modulate several effects of ghrelin, such as locomotor activity, memory, and food intake. Ghrelin increases dopamine levels in the shell of the n... | ['Analysis of Variance', 'Animals', 'Avoidance Learning', 'Dopamine Agents', 'Dose-Response Relationship, Drug', 'Drug Administration Routes', 'Drug Interactions', 'Eating', 'Ghrelin', 'Injections, Intraventricular', 'Motor Activity', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Dopamine', 'Taste', 'Time Factors'] | 23,624,808 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.267'], ['G07.690.773.968'], ['G07.203.650.283', 'G10.261.330'], ['D06.472.699.301', 'D12.644.548.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The cancer-screening dilemma. | Only in cancer of the uterine cervix and in cancer of the breast is there evidence of reduced mortality with early treatment. Screening also enables physicians to detect early cancer of the oral cavity or colon. With regard to cancers at other sites, many questions about screening's potential remain to be answered. | ['Adolescent', 'Adult', 'Breast Neoplasms', 'Colonic Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Neoplasms', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 673,982 | [['M01.060.057'], ['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.443.591', 'C07.465.530'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The solution conformation of tubulin-beta(422-434)-NH2 and its Nac-DATADEQG-NH2 fragment based on NMR. | The solution conformation of tubulin-beta(422-434)-NH2 (YQQYQDATADEQG-NH2) and its Nac-DATADEQG-NH2 fragment has been studied by two-dimensional 1H-nmr spectroscopy in CD3OH/H2O (90/10 v/v) at neutral and low pH. The 13 amino acid peptide is a segment of the C-terminal region of tubulin, and is directly involved in the... | ['Amino Acid Sequence', 'Circular Dichroism', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Peptide Fragments', 'Protein Conformation', 'Solutions', 'Temperature', 'Tubulin'] | 1,863,694 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.867.151'], ['E05.196.867.519'], ['L01.453.245.667'], ['D12.644.541'], ['G02.111.570.820.709'], ['D26.776'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D05.750.078.734.800', 'D12.776.220.600.800... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Behavioral effects of nimodipine in animals. | Neuro- and psychopharmacological effects of isopropyl-(2-methoxy-ethyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (Bay e 9736, nimodipine) are described using a variety of methods measuring behavior under normal conditions, under the influence of psychotropic drugs, as well as under the influ... | ['Aggression', 'Animals', 'Anticonvulsants', 'Behavior, Animal', 'Brain Ischemia', 'Calcium Channel Blockers', 'Catalepsy', 'Cats', 'Conditioning, Operant', 'Electrocardiography', 'Female', 'Humans', 'Hypoxia', 'Male', 'Mice', 'Motor Activity', 'Nicotinic Acids', 'Nimodipine', 'Postural Balance', 'Rats', 'Rats, Inbred ... | 7,201,803 | [['F01.145.126.125', 'F01.145.813.045'], ['B01.050'], ['D27.505.954.427.080'], ['F01.145.113'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['C10.597.350.200', 'C23.888.592.350.200'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['F02.463.425.17... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Properties of D2 dopamine receptor autoradiography: high percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections. | [3H]Spiroperidol (spiperone) binding in the presence of mianserin, a serotonin (5-HT2) receptor antagonist, was characterized in rat brain using quantitative autoradiography. All binding parameters were directly determined from film densities. Competition and kinetic studies revealed that [3H]spiroperidol binds to a si... | ['Animals', 'Autoradiography', 'Binding, Competitive', 'Brain', 'Corpus Striatum', 'Dopamine', 'Guanylyl Imidodiphosphate', 'In Vitro Techniques', 'Kinetics', 'Male', 'Mianserin', 'Rats', 'Rats, Inbred Strains', 'Receptors, Dopamine', 'Spiperone'] | 3,768,686 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A08.186.211'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.633.100.759.646.454.504.400', 'D13.695.667.454.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nanofibers mat-based solid-phase extraction method for the pretreatment of urine samples and its application in the primary study on the disposition of nonylphenol after long-term low-level exposure in rats. | A method was established for the analysis of nonylphenol (NP) in rat urine samples based on a solid-phase extraction (SPE) procedure with an amino functionalized polyacrylonitrile nanofibers mat (NH2-PAN NFSM) as sorbent coupled with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The cali... | ['Animals', 'Chromatography, High Pressure Liquid', 'Female', 'Limit of Detection', 'Linear Models', 'Nanofibers', 'Phenols', 'Rats', 'Rats, Sprague-Dawley', 'Reproducibility of Results', 'Solid Phase Extraction', 'Tandem Mass Spectrometry', 'Toxicity Tests, Chronic'] | 28,772,224 | [['B01.050'], ['E05.196.181.400.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['J01.637.512.300'], ['D02.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mus spicilegus endogenous retrovirus HEMV uses murine sodium-dependent myo-inositol transporter 1 as a receptor. | We sought to determine the relationship between two recent additions to the murine leukemia virus (MLV) ecotropic subgroup: Mus cervicolor isolate M813 and Mus spicilegus endogenous retrovirus HEMV. Though divergent in sequence, the two viruses share an Env protein with similarly curtailed VRA and VRB regions, and infe... | ['Amino Acid Sequence', 'Animals', 'Endogenous Retroviruses', 'Leukemia Virus, Murine', 'Mice', 'Molecular Sequence Data', 'Receptors, Virus', 'Sequence Homology, Amino Acid', 'Symporters', 'Viral Envelope Proteins', 'Virus Internalization'] | 22,457,525 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B04.613.807.250', 'B04.820.650.250', 'G02.111.570.080.708.330.800.175', 'G05.360.080.708.330.800.175', 'G05.360.340.024.425.800.175'], ['B04.613.807.375.525', 'B04.820.650.375.525'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['D12.776.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Polyetheretherketone (PEEK) cages for anterior column reconstruction in pyogenic vertebral osteomyelitis. | The objective of study was to evaluate a case series of patients in whom polyetheretherketone (PEEK) cages were used for anterior column reconstruction in vertebral osteomyelitis. Fifteen patients underwent clinical and radiological evaluation with average follow-up of 26 months. Parameters assessed were time of surger... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Female', 'Humans', 'Internal Fixators', 'Ketones', 'Kyphosis', 'Lordosis', 'Male', 'Middle Aged', 'Osteomyelitis', 'Polyethylene Glycols', 'Spinal Fusion', 'Titanium', 'Treatment Outcome'] | 30,987,501 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.370', 'E07.858.442.660.460', 'E07.858.690.725.460'], ['D02.522'], ['C05.116.900.800.500'], ['C05.116.900.800.750'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Association study of bipolar disorder using a functional polymorphism (Ser311-->Cys) in the dopamine D2 receptor gene. | Several pieces of evidence are consistent with the involvement of dopamine neurotransmission in the aetiology of bipolar disorder. We have tested the hypothesis that the functional mutation Ser311-->Cys of the dopamine D2 receptor gene confers susceptibility to bipolar disorder. There was no increased frequency of the ... | ['Alleles', 'Bipolar Disorder', 'Codon', 'DNA Mutational Analysis', 'European Continental Ancestry Group', 'Genes', 'Genetic Predisposition to Disease', 'Humans', 'Point Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Psychotic Disorders', 'Receptors, Dopamine D2', 'Schizophrenia', 'United Kingdom'] | 7,551,964 | [['G05.360.340.024.340.030'], ['F03.084.500'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['E05.393.760.700.300'], ['M01.686.508.400'], ['G05.360.340.024.340'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.675'], ['E05.393.620.500... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Geochemical modeling of arsenic release from a deep natural solid matrix under alternated redox conditions. | Dissolved arsenic (As) concentrations detected in groundwater bodies of the Emilia-Romagna Region (Italy) exhibit values which are above the regulation limit and could be related to the natural composition of the host porous matrix. To support this hypothesis, we present the results of a geochemical modeling study repr... | ['Arsenic', 'Groundwater', 'Italy', 'Minerals', 'Models, Chemical', 'Oxidation-Reduction', 'Water Pollutants, Chemical'] | 23,949,112 | [['D01.268.513.249'], ['G01.311.355'], ['Z01.542.489'], ['D01.578'], ['E05.599.495'], ['G02.700', 'G03.295.531'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Local inflammation in fracture hematoma: results from a combined trauma model in pigs. | Background. Previous studies showed significant interaction between the local and systemic inflammatory response after severe trauma in small animal models. The purpose of this study was to establish a new combined trauma model in pigs to investigate fracture-associated local inflammation and gain information about the... | ['Animals', 'Enzyme-Linked Immunosorbent Assay', 'Hematoma', 'Inflammation', 'Interleukin-10', 'Interleukin-6', 'Interleukin-8', 'Male', 'Multiple Trauma', 'Swine'] | 25,694,748 | [['B01.050'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C23.550.414.838'], ['C23.550.470'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of pulsed magnetic field therapy on the level of fatigue in patients with multiple sclerosis--a randomized controlled trial. | Twenty-five multiple sclerosis patients, taking part in a rehabilitation program, were randomly assigned to treatment with pulsed magnetic field therapy (PMFT) or to sham therapy in order to study the additional effect of PMFT as part of a multimodal neurological rehabilitation program on fatigue. Patients demographic ... | ['Adult', 'Bed Rest', 'Electric Stimulation Therapy', 'Exercise', 'Fatigue', 'Female', 'Humans', 'Inpatients', 'Magnetics', 'Male', 'Middle Aged', 'Multiple Sclerosis, Chronic Progressive', 'Multiple Sclerosis, Relapsing-Remitting', 'Severity of Illness Index'] | 15,957,511 | [['M01.060.116'], ['E02.075'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['G11.427.410.698.277', 'I03.350'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['H01.671.493'], ['M01.060.116.630'], ['C10.114.375.500.200', 'C10.314.350.500.200', 'C20.111.258.250.500.200'], ['C10.114.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Individual psychosocial support for breast cancer patients: a randomized study of nurse versus psychologist interventions and standard care. | In a prospective, randomized study, an individual psychosocial support intervention performed by specially trained oncology nurses, or psychologists, were compared with standard care. Consecutive primary breast cancer patients about to start adjuvant therapy (n = 179) were included. Data were supplied by the questionna... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Breast Neoplasms', 'Emotions', 'Female', 'Humans', 'Middle Aged', 'Oncology Nursing', 'Prospective Studies', 'Psychological Techniques', 'Quality of Life', 'Treatment Outcome'] | 17,510,577 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['C04.588.180', 'C17.800.090.500'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.478.676.605', 'N02.421.533.600'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
CSF monoamine metabolites in depression and schizophrenia. | The authors report cerebrospinal fluid (CSF) concentrations of five monoamine metabolites before and after probenecid administration in normal subjects and patients with depression and schizophrenia. No differences were found in baseline metabolite concentrations among the three groups. CSF metabolite and CSF probeneci... | ['3,4-Dihydroxyphenylacetic Acid', 'Depression', 'Homovanillic Acid', 'Humans', 'Hydroxyindoleacetic Acid', 'Male', 'Methoxyhydroxyphenylglycol', 'Probenecid', 'Schizophrenia'] | 7,352,572 | [['D02.241.223.601.220'], ['F01.145.126.350'], ['D02.241.223.601.521'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['D02.033.455.250.610'], ['D02.065.884.625', 'D02.886.590.700.625'], ['F03.700.750']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Idiopathic central retinal vein occlusion in a thrombophilic patient with the heterozygous 20210 G/A prothrombin genotype. | PURPOSE: To report the occurrence of monolateral central retinal vein occlusion in a patient with heterozygous 20210 G/A prothrombin genotype, known to be associated with high thrombophilic risk.METHODS: A monolateral central retinal vein occlusion was diagnosed in a 71-year-old woman, who had suffered from a deep vein... | ['Aged', 'DNA', 'Female', 'Fluorescein Angiography', 'Fundus Oculi', 'Heterozygote', 'Humans', 'Point Mutation', 'Polymerase Chain Reaction', 'Prothrombin', 'Retinal Vein Occlusion', 'Risk Factors', 'Thrombophilia'] | 10,458,191 | [['M01.060.116.100'], ['D13.444.308'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.675'], ['E05.393.620.500'], ['D08.622.709', 'D12.776.124.125.800', 'D12.776.811.243.709', 'D23.119.945'], ['C11.768.760', 'C14.907.355.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of simulated acid snow stress on leaf tissue of wintering herbaceous plants. | Acid snow might be an environmental stress factor for wintering plants since acid precipitates are locally concentrated in snow and the period in which ice crystals are in contact with shoots might be longer than that of acid precipitates in rain. In this study, 'equilibrium' and 'prolonged' freezing tests with sulfuri... | ['Acids', 'Cold Temperature', 'Environmental Exposure', 'Freezing', 'Hydrogen-Ion Concentration', 'Plant Leaves', 'Rain', 'Seasons', 'Seedlings', 'Snow', 'Sulfuric Acids', 'Time Factors', 'Triticum'] | 16,481,360 | [['D01.029'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['N06.850.460.350'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['G02.300'], ['A18.024.812'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical and laboratory markers of hypersensitivity to trimethoprim-sulfamethoxazole in patients with Pneumocystis carinii pneumonia and AIDS. | A group of clinical, immunologic, and virologic variables was examined to determine if any predicted the development of hypersensitivity to trimethoprim-sulfamethoxazole (TMP-SMZ) during treatment of Pneumocystis carinii pneumonia in patients with human immunodeficiency virus (HIV) infection. Hypersensitivity occurred ... | ['AIDS-Related Opportunistic Infections', 'Adrenal Cortex Hormones', 'Adult', 'Aged', 'Antibodies, Viral', 'CD4-CD8 Ratio', 'Cytomegalovirus Infections', 'Drug Hypersensitivity', 'Humans', 'Immunoglobulins', 'Male', 'Middle Aged', 'Pneumonia, Pneumocystis', 'Regression Analysis', 'Trimethoprim, Sulfamethoxazole Drug Co... | 8,380,290 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['D06.472.040'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E01.370.225.500.195.107.595.500.150.160... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The â subunit of yeast AMP-activated protein kinase directs substrate specificity in response to alkaline stress. | Saccharomyces cerevisiae express three isoforms of Snf1 kinase that differ by which â subunit is present, Gal83, Sip1 or Sip2. Here we investigate the abundance, activation, localization and signaling specificity of the three Snf1 isoforms. The relative abundance of these isoforms was assessed by quantitative immunoblo... | ['AMP-Activated Protein Kinases', 'Alkalies', 'Cell Nucleus', 'Conserved Sequence', 'Enzyme Activation', 'Glucose', 'Histidine', 'Isoenzymes', 'Kinetics', 'Mutant Proteins', 'Phosphorylation', 'Protein Subunits', 'Protein Transport', 'Protein-Serine-Threonine Kinases', 'Saccharomyces cerevisiae', 'Stress, Physiological... | 27,592,031 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['D01.045'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G02.111.570.580'], ['G02.111.263', 'G03.328'], ['D09.947.875.359.448'], ['D12.125.072.329', 'D12.125.142.308'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rats' midsession reversal performance: the nature of the response. | The midsession reversal task involves a simple simultaneous discrimination that predictably reverses midway through a session. Under various conditions, pigeons generally both anticipate the reversal and perseverate once it has occurred, whereas rats tend to make very few of either kind of error. In the present researc... | ['Animals', 'Columbidae', 'Conditioning, Operant', 'Discrimination Learning', 'Rats', 'Reversal Learning', 'Species Specificity'] | 26,202,589 | [['B01.050'], ['B01.050.150.900.248.165.150'], ['F02.463.425.179.509'], ['F02.463.425.280'], ['B01.050.150.900.649.313.992.635.505.700'], ['F02.463.425.798'], ['G16.824']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combined liver-kidney transplantation versus liver transplant alone based on KDIGO stratification of estimated glomerular filtration rate: data from the United Kingdom Transplant registry - a retrospective cohort study. | Patient selection for combined liver-kidney transplantation (CLKT) is a current issue on the background of organ shortage. This study aimed to compare outcomes and post-transplant renal function for patients receiving CLKT and liver transplantation alone (LTA) based on native renal function using estimated glomerular f... | ['Female', 'Glomerular Filtration Rate', 'Graft Survival', 'Humans', 'Kidney Transplantation', 'Liver Transplantation', 'Male', 'Middle Aged', 'Registries', 'Retrospective Studies', 'Risk Factors', 'United Kingdom'] | 30,793,378 | [['E01.370.390.400.300', 'G08.852.357'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Enrichment of total flavonoids from Spatholobus suberectus by macroporous adsorption resin]. | OBJECTIVE: To screen different macroporous adsorption resins for isolation and purification of flavonoids from Spatholobus suberectus.METHODS: 6 kinds of macroporous adsorption resins were assayed for their adsorbability and deadsorbability of total flavonoids from Spatholobus suberectus.RESULTS: HPD 400 resin was foun... | ['Adsorption', 'Ethanol', 'Fabaceae', 'Flavonoids', 'Plant Stems', 'Plants, Medicinal', 'Resins, Synthetic', 'Spectrophotometry, Ultraviolet', 'Technology, Pharmaceutical'] | 21,434,446 | [['G01.030', 'G02.020'], ['D02.033.375'], ['B01.650.940.800.575.912.250.401'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A18.024.937'], ['B01.650.560'], ['D05.750.716.822', 'D25.339.816', 'D25.720.716.822', 'J01.637.051.339.816', 'J01.637.051.720.716.822'], ['E05.196.712.726.802', 'E05.196.867.826.802']... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Analysis of benzodiazepines and tricyclic antidepressants in serum using a common solid-phase clean-up and a common mobile phase. | A single, rapid and specific solid-phase clean-up procedure was developed for the analysis of benzodiazepines and tricyclic antidepressants using a carefully selected wash step and specific sequential elution. Benzodiazepines were eluted from the solid-phase column using as mixture of water-methanol-acetonitrile (2:3:3... | ['Anti-Anxiety Agents', 'Antidepressive Agents, Tricyclic', 'Benzodiazepines', 'Chromatography, High Pressure Liquid', 'Humans', 'Spectrophotometry, Ultraviolet'] | 2,576,269 | [['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D27.505.954.427.700.122.055'], ['D03.633.100.079.080'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Randomised controlled trial of azathioprine withdrawal in autoimmune chronic active hepatitis. | To assess the value of azathioprine in the maintenance therapy of autoimmune chronic active hepatitis a controlled trial of azathioprine withdrawal was carried out in 50 patients who had been maintained in remission on a combination of azathioprine and prednisolone. The patients were randomly allocated to remain on com... | ['Adult', 'Aged', 'Autoimmune Diseases', 'Azathioprine', 'Clinical Trials as Topic', 'Drug Therapy, Combination', 'Female', 'Hepatitis, Chronic', 'Humans', 'Male', 'Middle Aged', 'Prednisolone', 'Random Allocation'] | 2,858,619 | [['M01.060.116'], ['M01.060.116.100'], ['C20.111'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.319.310'], ['C06.552.380.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D04.210.500.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Just blowing smoke? Social desirability and reporting of intentions to quit smoking. | INTRODUCTION: Do cigarette smokers really want to quit smoking or do they simply say they do in order to placate others and avoid criticism? In surveys of smokers, stated quit intentions and reports of quit attempts may be biased by social desirability concerns. This makes it difficult to interpret large-scale state an... | ['Adult', 'Aged', 'Data Collection', 'Female', 'Humans', 'Intention', 'Male', 'Middle Aged', 'Smoking', 'Smoking Cessation', 'Social Desirability', 'Telephone', 'Tobacco Use Disorder', 'United States', 'Young Adult'] | 23,884,318 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['M01.060.116.630'], ['F01.145.805'], ['F01.145.488.732'], ['F01.145.813.628'], ['L01.178.847.698'], ['C25.775.912', 'F03.900.912'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Protracted post-traumatic confusional state treated with physostigmine. | A case study is presented of confusion in a head-injured man, lasting for more than 2 years, when intermittent treatment with physostigmine resulted in progressive improvement in both confusion and usable cognitive functions. Aetiological mechanisms and implications for treatment plans are discussed. | ['Awareness', 'Cholinesterase Inhibitors', 'Confusion', 'Electroencephalography', 'Follow-Up Studies', 'Glasgow Coma Scale', 'Head Injuries, Closed', 'Humans', 'Male', 'Middle Aged', 'Physostigmine'] | 8,680,399 | [['F02.463.188.150'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['E01.370.376.300', 'E01.370.405.245'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.940.968.875.250... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Progress's Pilgrim: a critical narrative of research in progress. | There is increasing interest in the use of stories to develop nursing and health care practice. This paper reports on how we used story to understand and develop research on nursing practice. Story (or narrative) and science can be seen as distinct but complementary paradigms. We have found that a story framework can h... | ['Community Mental Health Services', 'Humans', 'Nursing Research', 'Psychiatric Nursing', 'Research Design', 'Scotland'] | 10,320,507 | [['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['H02.478.676.710', 'N02.421.533.778'], ['E05.581.500', 'H01.770.644.728'], ['Z01.542.363.766']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Spinal cord infarction following therapeutic renal artery embolization. | A patient with dialysis cachexia became paraparetic within hours of therapeutic renal artery embolization. At autopsy, emboli of absorbable gelatin sponge filled spinal arteries, accompanied by spinal cord infarcts. The renal arteries of patients with end-stage renal disease are smaller than normal becaue of intimal fi... | ['Adult', 'Cachexia', 'Embolization, Therapeutic', 'Female', 'Gelatin Sponge, Absorbable', 'Humans', 'Infarction', 'Kidney Failure, Chronic', 'Renal Artery', 'Renal Dialysis', 'Spinal Cord'] | 577,249 | [['M01.060.116'], ['C23.888.144.243.963.500.500'], ['E02.520.360', 'E02.926.500'], ['E07.858.740.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513.355', 'C23.550.717.489'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['A07.015.114.745'], ['E02.870.300', 'E02.912.800'], ['A08.186.854'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Glomerular extracellular roughly granular material (ERGM). Its autofluorescent property and the question of its nuclear origin. | A glomerular extra-cellular roughly granular material (ERGM) has been described by several authors, mainly in association with membranoproliferative glomerulonephritis. This material is clearly identified on light and electron microscopy. Another peculiar morphological character of ERGM is its property of autofluoresce... | ['Cell Nucleus', 'Complement System Proteins', 'DNA', 'Extracellular Matrix', 'Fluorescence', 'Humans', 'Kidney Glomerulus'] | 3,601,802 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.776.124.486.274'], ['D13.444.308'], ['A11.284.295.310'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.324.359', 'A05.810.453.736.520']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased prevalence of intestinal helminth infection during pregnancy in a Sub-Saharan African community. | Gestation is a unique physiologic state that carries with it several immunologic consequences and results in changing susceptibility to various diseases. In contrast to the well recognized excess vulnerability of primiparous women to Plasmodium falciparum infection in areas of high malaria transmission, it is not known... | ['Adult', 'Africa South of the Sahara', 'Disease Outbreaks', 'Female', 'Helminthiasis', 'Humans', 'Intestinal Diseases, Parasitic', 'Pregnancy', 'Pregnancy Complications, Parasitic', 'Prevalence', 'Risk Assessment'] | 18,157,604 | [['M01.060.116'], ['Z01.058.290'], ['N06.850.290'], ['C01.610.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.432', 'C06.405.469.452'], ['G08.686.784.769'], ['C01.610.718', 'C13.703.700.680'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.75... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Grassland management for horses. | The pasture needs for horses as compared to those for farm livestock are reviewed. The differing preferences of various types of grasses and other plants, and the patterns of grazing seen on"horse-sick" pastures, are discussed. Suggestions for practical management include frequent collection and removal of droppings, t... | ['Animal Feed', 'Animals', 'Defecation', 'Feeding Behavior', 'Female', 'Fertilizers', 'Horses', 'Male', 'Poaceae'] | 6,255,672 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G10.261.165'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D27.720.031.400'], ['B01.050.150.900.649.313.984.235.472'], ['B01.650.940.800.575.912.250.822']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Breast magnetic resonance imaging for screening high-risk women. | Mammography is the only imaging modality that has been validated by multiple randomized clinical trials and meta-analyses to reduce mortality from breast cancer. Although it is demonstrated to be effective in reducing mortality from breast cancer, mammography has its limitations, especially in young high-risk women wit... | ['BRCA1 Protein', 'BRCA2 Protein', 'Breast Neoplasms', 'Early Detection of Cancer', 'Evidence-Based Medicine', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Magnetic Resonance Imaging', 'Prevalence', 'Reproducibility of Results', 'Risk Assessment', 'Sensitivity and Specificity', "Women's Health"] | 23,928,241 | [['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['D12.776.313.249', 'D12.776.624.776.101', 'D12.776.660.105'], ['C04.588.180', 'C17.800.090.500'], ['E01.390.500'], ['H02.249.750', 'H02.403.200.400'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production. | The hypoglycemia seen in the fasting PPARalpha null mouse is thought to be due to impaired liver fatty acid beta-oxidation. The etiology of hypoglycemia in the PPARalpha null mouse was determined via stable isotope studies. Glucose, lactate, and glycerol flux was assessed in the fasted and fed states in 4-month-old PPA... | ['Animals', 'Base Sequence', 'Blood Glucose', 'Carbon Isotopes', 'DNA Primers', 'Fasting', 'Gene Expression Regulation, Enzymologic', 'Gluconeogenesis', 'Glucose', 'Glycerol', 'Homeostasis', 'Insulin', 'Lactic Acid', 'Liver', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Models, Biological', 'Phosphoenolpyruvate Car... | 12,176,975 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D09.947.875.359.448.500'], ['D01.268.150.075', 'D01.496.123'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G05.308.320'], ['G02.111.158.500', 'G03.191.500'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Probabilistic Modeling of Dietary Arsenic Exposure and Dose and Evaluation with 2003-2004 NHANES Data. | BACKGROUND: Dietary exposure from food to toxic inorganic arsenic (iAs) in the general U.S. population has not been well studied.OBJECTIVES: The goal of this research was to quantify dietary As exposure and analyze the major contributors to total As (tAs) and iAs. Another objective was to compare model predictions with... | ['Arsenic', 'Biomarkers', 'Diet', 'Environmental Exposure', 'Food Contamination', 'Humans', 'Models, Statistical', 'Nutrition Surveys', 'Probability', 'Risk Assessment', 'Time Factors', 'United States', 'Water Pollutants, Chemical', 'Water Supply'] | 20,194,069 | [['D01.268.513.249'], ['D23.101'], ['G07.203.650.240'], ['N06.850.460.350'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.308.980.485', 'N05.715.360.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The relationship of homocyteine, B12 and folic acid with the bone mineral density of the femur and lumbar spine in Turkish postmenopausal women. | OBJECTIVE: The relationship of homocyteine, B12 and folic acid with osteoporosis has already been studied in various populations. We compared the important factors in the metabolism of homocysteine, such as homocysteine, B12 and folic acid levels, of Turkish postmenopausal women, and their relationship with the femur a... | ['Absorptiometry, Photon', 'Adult', 'Aged', 'Bone Density', 'Cross-Sectional Studies', 'Female', 'Femur', 'Folic Acid', 'Homocysteine', 'Humans', 'Lumbar Vertebrae', 'Middle Aged', 'Osteoporosis', 'Postmenopause', 'Turkey', 'Vitamin B 12'] | 19,151,987 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['M01.060.116.100'], ['G11.427.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A02.835.232.043.150'], ['D03.633.100.733.631.400'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Occupational exposure to blood and other bodily fluids at a military hospital in Iraq. | BACKGROUND: Exposure to bloodborne pathogens, namely HIV, hepatitis B, and hepatitis C, remains a risk for healthcare workers. Given the austere and challenging environments in a combat zone, it is unclear to what extent blood and other bodily fluid occupational exposures pose a risk of infection for military healthcar... | ['Accidents, Occupational', 'Blood-Borne Pathogens', 'Hospitals, Military', 'Humans', 'Incidence', 'Iraq War, 2003-2011', 'Needlestick Injuries', 'Personnel, Hospital', 'Retrospective Studies', 'Trauma Centers'] | 19,359,972 | [['N06.850.135.240'], ['B05.155'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['I01.880.735.950.250.782', 'K01.400.504.984.249'], ['C26.986.950.500'], ['M01.526.485.740', ... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Paromomycin for cryptosporidiosis in AIDS: a prospective, double-blind trial. | To test the effects of paromomycin, 10 patients with AIDS and cryptosporidiosis were randomized to paromomycin or placebo in a double-blind trial. After 14 days, patients were switched to the other treatment for 14 additional days. Measures included the number and character of each stool and weekly 24-h stool specimens... | ['AIDS-Related Opportunistic Infections', 'Adult', 'Cryptosporidiosis', 'Diarrhea', 'Double-Blind Method', 'Feces', 'Humans', 'Longitudinal Studies', 'Parasite Egg Count', 'Paromomycin', 'Prospective Studies'] | 8,035,029 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['M01.060.116'], ['C01.610.432.269', 'C01.610.701.688.235', 'C01.610.752.250.269', 'C01.610.752.625.235', 'C06.405.469.452.269', 'C22.674.710.235'], ['C23.888.821.214'], ['E05.318.370.300', '... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Child maltreatment risk among adolescent mothers: a study of reported cases. | A large random sample of reported child maltreatment incidents are analyzed in terms of the research question: Is there a higher incidence of maltreatment by women who were adolescent mothers than by older mothers? Results from the official records studied indicate similar dynamic variables reported for both groups of... | ['Adolescent', 'Age Factors', 'Child', 'Child Abuse', 'Ethnic Groups', 'Female', 'Humans', 'Marriage', 'Mothers', 'Pregnancy', 'Socioeconomic Factors'] | 7,406,033 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N0... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. | Alkaloids isolated from the Amaryllidaceae plants have potential as therapeutics for treating human diseases. Haemanthamine has been studied as a novel anticancer agent due to its ability to overcome cancer cell resistance to apoptosis. Biochemical experiments have suggested that hemanthamine targets the ribosome. Howe... | ['Amaryllidaceae Alkaloids', 'Antineoplastic Agents', 'Binding Sites', 'Cell Proliferation', 'Colonic Neoplasms', 'Crystallography, X-Ray', 'HCT116 Cells', 'Humans', 'Models, Molecular', 'Molecular Conformation', 'Phenanthridines', 'RNA, Ribosomal', 'Ribosomes', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Pro... | 29,429,877 | [['D03.132.052'], ['D27.505.954.248'], ['G02.111.570.120'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E05.196.309.742.225'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['B01.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Granulocyte superoxide anion and elastase release during cardiopulmonary bypass. | Cardiopulmonary bypass (CPB) is known to induce several pathogenic responses in cardiovascular surgery. To explore leukocyte activation during PCB, we investigated superoxide anion (O2-) production by granulocytes in 6 patients undergoing aortocoronary bypass surgery. O2- production was determined with chemiluminescenc... | ['Aged', 'Cardiopulmonary Bypass', 'Complement C3a', 'Complement C4a', 'Female', 'Granulocytes', 'Humans', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Pancreatic Elastase', 'Superoxides'] | 8,274,101 | [['M01.060.116.100'], ['E04.292.413'], ['D12.776.124.486.274.024.250', 'D12.776.124.486.274.250.250'], ['D12.776.124.486.274.024.260', 'D12.776.124.486.274.350.250'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Microarray analysis of Tbx2-directed gene expression: a possible role in osteogenesis. | Tbx2 is a member of the developmentally important transcriptional regulatory T-box gene family, whose target genes have not been well characterized. In an attempt to identify genes that may be regulated by Tbx2, mouse cDNA microarrays were used to analyze differential gene expression profiles, comparing stably transfec... | ['3T3 Cells', 'Animals', 'Caveolins', 'Cell Adhesion', 'Cell Movement', 'Chondrocytes', 'Databases, Factual', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Humans', 'Mice', 'Morphogenesis', 'Oligonucleotide Array Sequence Analysis', 'Osteoblasts', 'Osteogenesis', 'Rats', 'T-Box Domain Proteins', 'Transfec... | 11,377,819 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['D12.776.543.990.100'], ['G04.022'], ['G04.198', 'G07.568.500.180'], ['A11.329.171'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.393.332'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An E3 Ligase Affects the NLR Receptor Stability and Immunity to Powdery Mildew. | Following the detection of pathogen cognate effectors, plant Nod-like receptors (NLRs) trigger isolate-specific immunity that is generally associated with cell death. The regulation of NLR stability is important to ensure effective immunity. In barley (Hordeum vulgare), the allelic Mildew locus A (MLA) receptors mediat... | ['Ascomycota', 'Cell Death', 'Disease Resistance', 'Genetic Loci', 'Hordeum', 'Plant Diseases', 'Plant Immunity', 'Plant Proteins', 'Plants, Genetically Modified', 'Proteasome Endopeptidase Complex', 'Protein Binding', 'Proteolysis', 'Ubiquitin-Protein Ligases', 'Ubiquitination'] | 27,780,896 | [['B01.300.107'], ['G04.146'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['G05.360.340.024.380'], ['B01.650.940.800.575.912.250.822.481'], ['G15.610'], ['G12.450.800', 'G15.630'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control of segregation of chromosomal DNA by sex factor F in Escherichia coli. Mutants of DNA gyrase subunit A suppress letD (ccdB) product growth inhibition. | The letA (ccdA) and letD (ccdB) genes, located just outside the sequence essential for replication of the F plasmid, apparently contribute to stable maintenance of the plasmid. The letD gene product acts to inhibit partitioning of chromosomal DNA and cell division of the host bacteria, whereas the letA gene product act... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Bacterial Toxins', 'Base Sequence', 'Chromosomes, Bacterial', 'DNA Topoisomerases, Type II', 'DNA, Bacterial', 'Escherichia coli', 'F Factor', 'Genes, Bacterial', 'Genetic Complementation Test', 'Molecular Sequence Data', 'Phenotype', 'Restriction Mapping', 'Temperature'] | 1,316,444 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D23.946.123'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['D08.811.399.403.741'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.600.300'], ['G05.36... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Ovarian, peritoneal, and endometrial serous carcinoma: clonal origin of multifocal disease. | The clonality of disseminated serous carcinoma involving the ovary, peritoneum, and, occasionally, the endometrium is controversial. Histopathologic examination alone cannot unequivocally distinguish between a monoclonal origin and a multicentric origin. Two patients with peritoneal serous carcinoma with minimal ovaria... | ['Aged', 'Cystadenocarcinoma, Serous', 'Endometrial Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Mutation', 'Ovarian Neoplasms', 'Peritoneal Neoplasms', 'Polymorphism, Single-Stranded Conformational'] | 8,685,209 | [['M01.060.116.100'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.590'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey. | BACKGROUND & AIMS: A genome-wide association study associated 5 genetic variants with hepatic steatosis (identified by computerized tomography) in individuals of European ancestry. We investigated whether these variants were associated with measures of hepatic steatosis (HS) in non-Hispanic white (NHW), non-Hispanic bl... | ['Adaptor Proteins, Signal Transducing', 'Adult', 'African Continental Ancestry Group', 'Aged', 'European Continental Ancestry Group', 'Fatty Liver', 'Female', 'Gene Frequency', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Humans', 'Lipase', 'Male', 'Membrane Proteins', 'Mexican Americans', 'Mid... | 23,416,328 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['M01.686.508.400'], ['C06.552.241'], ['G05.330'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.100.400'], ['D12.776.543']... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparative proteomes, immunoreactivities and neutralization of procoagulant activities of Calloselasma rhodostoma (Malayan pit viper) venoms from four regions in Southeast Asia. | The intraspecific geographical venom variations of Calloselasma rhodostoma from Malaysia (CR-M), Indonesia (CR-I), Thailand (CR-T) and Vietnam (CR-V) were investigated through 1D SDS-PAGE and nano-ESI-LCMS/MS. The venom antigenicity, procoagulant activities and neutralization using Thai C. rhodostoma Monovalent Antiven... | ['Animals', 'Coagulants', 'Crotalid Venoms', 'Crotalinae', 'Indonesia', 'Malaysia', 'Proteome', 'Thailand', 'Vietnam'] | 31,445,943 | [['B01.050'], ['D27.505.954.502.270'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['B01.050.150.900.833.672.125.937.240'], ['Z01.252.145.380', 'Z01.639.580'], ['Z01.252.145.487'], ['D12.776.817'], ['Z01.252.145.841'], ['Z01.252.145.945']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Efficient preparation of aminoxyacyl amides, aminoxy hybrid peptides, and alpha-aminoxy peptides. | N-(Pg-alpha-aminoxy acids) 1a-g are converted to N-(Pg-alpha-aminoxyacyl)benzotriazoles 2a-g, which react under mild conditions with amines, alpha-amino acids/alpha-dipeptides, and alpha-aminoxy acids to give aminoxyacyl amides 3a-g, (3e+3e'), and (3g+3g'), aminoxy hybrid peptides 4a-h, (4a+4a'), 6a-d, 9a-e, (9a+9a'), ... | ['Amides', 'Molecular Conformation', 'Oligopeptides', 'Stereoisomerism'] | 19,831,362 | [['D02.065'], ['G02.111.570.820'], ['D12.644.456'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphology of physiologically characterized medial lemniscal axons terminating in cat ventral posterior thalamic nucleus. | 1. Medial lemniscal axons were identified by extra- and intracellular recording in the thalamic ventral posterior lateral nucleus (VPL) of cats and injected intracellularly with horseradish peroxidase (HRP). 2. Axons were characterized in terms of their latencies of response to stimulation of the medial lemniscus in th... | ['Animals', 'Axons', 'Cats', 'Neural Pathways', 'Thalamic Nuclei'] | 3,193,165 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.612'], ['A08.186.211.200.317.826.701']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alterations in peak inspiratory pressure and tidal volume delivered by manually operated self-inflating resuscitation bags as a function of the oxygen supply rate. | OBJECTIVE: To assess possible alterations in the tidal volume and peak inspiratory pressure delivered by seven models of manually operated self-inflating resuscitation bags as a function of the oxygen supply rate used.METHODS: The resuscitation bags tested were the following: Oxigel, models A and B; CE Reanimadores; Pr... | ['Humans', 'Inhalation', 'Intermittent Positive-Pressure Ventilation', 'Models, Biological', 'Oxygen', 'Oxygen Consumption', 'Pulmonary Ventilation', 'Respiration, Artificial', 'Resuscitation', 'Tidal Volume', 'Ventilators, Mechanical'] | 19,009,215 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.772.705.700.390'], ['E02.041.625.790.550', 'E02.880.820.790.550'], ['E05.599.395'], ['D01.268.185.550', 'D01.362.670'], ['G03.680'], ['E01.370.386.700.660', 'G09.772.650'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['E02.365.647'], ['E01.370.386.700.485.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. | In vivo, leukocyte transendothelial migration (TEM) occurs at endothelial cell junctions (paracellular) and nonjunctional (transcellular) locations, whereas in vitro models report that TEM is mostly paracellular. The mechanisms that control the route of leukocyte TEM remain unknown. Here we tested the hypothesis that e... | ['Amino Acid Sequence', 'Base Sequence', 'Cell Adhesion', 'Cell Movement', 'Cells, Cultured', 'Endothelium, Vascular', 'Green Fluorescent Proteins', 'Humans', 'In Vitro Techniques', 'Intercellular Adhesion Molecule-1', 'Neutrophils', 'Peptide Fragments', 'Recombinant Fusion Proteins', 'Recombinant Proteins', 'T-Lymphoc... | 15,811,956 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.022'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.532.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.776.395.550.200.450', 'D12.77... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Stunting Mediates the Association between Small-for-Gestational-Age and Postneonatal Mortality. | BACKGROUND: In sub-Saharan Africa, one-third of all births are small for gestational age (SGA), and 4.4 million children are stunted; both conditions increase the risk of child mortality. SGA has also been shown to increase the risk of stunting.OBJECTIVE: We tested whether the association between SGA and postneonatal m... | ['Africa South of the Sahara', 'Birth Weight', 'Female', 'Gestational Age', 'Growth Disorders', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Infant, Small for Gestational Age', 'Longitudinal Studies', 'Male', 'Socioeconomic Factors'] | 27,733,526 | [['Z01.058.290'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['G07.345.500.325.235.968', 'G08.686.320'], ['C23.550.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.308.985.550.475', 'N01.224.9... | ['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A 99mTc-Labeled Ligand of Carbonic Anhydrase IX Selectively Targets Renal Cell Carcinoma In Vivo. | UNLABELLED: Small organic ligands, selective for tumor-associated antigens, are increasingly being considered as alternatives to monoclonal antibodies for the targeted delivery of diagnostic and therapeutic payloads such as radionuclides and drugs into neoplastic masses. We have previously described a novel acetazolami... | ['Acetazolamide', 'Animals', 'Carbonic Anhydrase IX', 'Carcinoma, Renal Cell', 'Cell Line, Tumor', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Isotope Labeling', 'Kidney Neoplasms', 'Ligands', 'Mice', 'Technetium', 'Tissue Distribution', 'Tomography, Emission-Computed, Single-Photon'] | 26,912,427 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['B01.050'], ['D08.811.520.241.300.150.450', 'D12.776.543.178', 'D23.050.285.196'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['A11.251.210.190', 'A11.25... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short-term tests are unable to distinguish between human carcinogens and noncarcinogens. | Previously published results of short-term tests (STT) applied to chemicals, identified as carcinogens and noncarcinogens, are compared and discussed. Inspection of the data shows that carcinogens and noncarcinogens are about equally STT-positive. Although it may be possible to observe suggestive indications in the dat... | ['Animals', 'Carcinogens', 'Drug Evaluation, Preclinical', 'Mutagenicity Tests', 'Research Design', 'Time Factors'] | 3,719,413 | [['B01.050'], ['D27.888.569.100'], ['E05.290.750', 'E05.337.550'], ['E05.393.560', 'E05.940.560'], ['E05.581.500', 'H01.770.644.728'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral responses to physical vs. social novelty in male and female laboratory rats. | Most behavioral tests used with laboratory rodents involve measuring behavioral responses to physical novelty. However, laboratory rodents are often derived from highly social species for which novel social stimuli may induce different levels of fear or curiosity compared to novel physical objects. We hypothesized that... | ['Animals', 'Animals, Laboratory', 'Behavior, Animal', 'Exploratory Behavior', 'Fear', 'Female', 'Male', 'Rats', 'Rats, Sprague-Dawley'] | 21,726,606 | [['B01.050'], ['B01.050.050.199'], ['F01.145.113'], ['F01.145.387', 'F01.658.370'], ['F01.470.361'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuroimaging findings in a suprasellar granular cell tumor. | A 27-year-old woman presented with a history of amenorrhea, visual disturbance, and diabetes insipidus. Magnetic resonance imaging showed a large enhancing suprasellar mass with associated edema involving the left striatum. The lesion was hypometabolic on fluorodeoxyglucose-positron emission tomography. At surgery, a s... | ['Adult', 'Female', 'Fluorodeoxyglucose F18', 'Granular Cell Tumor', 'Humans', 'Hypothalamic Neoplasms', 'Magnetic Resonance Imaging', 'Pituitary Gland, Posterior', 'Pituitary Neoplasms', 'Radiopharmaceuticals', 'Tomography, Emission-Computed'] | 12,544,238 | [['M01.060.116'], ['D09.254.229.500'], ['C04.557.450.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.250.195.885.500', 'C10.228.140.211.885.500', 'C10.228.140.617.477', 'C10.551.240.250.700.500'], ['E01.370.350.825.500'], ['A06.300.747.875', 'A06.688.178.875', 'A06.688.357.750.875', 'A08.186.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
New anticancer active and selective phenylene-bisbenzothiazoles: synthesis, antiproliferative evaluation and DNA binding. | Novel amidino-derivatives of phenylene-bisbenzothiazoles were synthesized and tested for their antiproliferative activity against several human cancer cell lines, as well as DNA-binding properties. The synthetic approach used for preparation of isomeric amidino substituted-phenylene-bis-benzothyazoles 3a-3f was achieve... | ['Antineoplastic Agents', 'Apoptosis', 'Benzothiazoles', 'Cell Cycle', 'Cell Line', 'Cell Line, Tumor', 'Cell Proliferation', 'Circular Dichroism', 'DNA', 'Dose-Response Relationship, Drug', 'HeLa Cells', 'Humans', 'MCF-7 Cells', 'Models, Chemical', 'Molecular Structure', 'Nucleic Acid Denaturation', 'Spectrophotometry... | 23,603,616 | [['D27.505.954.248'], ['G04.146.954.035'], ['D03.383.129.708.089', 'D03.633.100.185'], ['G04.144'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.196.867.151'], ['D13.444.308'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.251.210.190.400', 'A11.251.860.180.400'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of cis- and trans-acting elements involved in the expression of cold shock-inducible TIP1 gene of yeast Saccharomyces cerevisiae. | Northern blot hybridization analysis of a series of 5' end, 3' end and internal deletions has revealed that at least four different regions are involved in the regulation of the expression of TIP1, a cold shock-inducible gene of Saccharomyces cerevisiae. One of these four regions has negative effect on the expression o... | ['Base Sequence', 'Blotting, Northern', 'Cold Temperature', 'Gene Expression Regulation, Fungal', 'Genes, Fungal', 'Molecular Sequence Data', 'Saccharomyces cerevisiae', 'Trans-Activators', 'Transcription, Genetic', 'Transcriptional Activation'] | 8,127,704 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G05.308.330'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.02... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Description and Impact Evaluation of a Statewide Collaboration to Reduce Preventable Hospital Readmissions. | This article describes how a Medicare-funded Quality Improvement Organization collaborated with a hospital association and multiple cross-continuum partners on a statewide effort to reduce hospital readmissions. Interventions included statewide education on quality improvement strategies and community-specific technica... | ['Attitude of Health Personnel', 'Communication', 'Community Participation', 'Fee-for-Service Plans', 'Humans', 'Inservice Training', 'Interinstitutional Relations', 'Medicare', 'Medication Reconciliation', 'Organizational Culture', 'Patient Readmission', 'Personnel Staffing and Scheduling', 'Practice Guidelines as Top... | 27,418,618 | [['F01.100.050', 'N05.300.100'], ['F01.145.209', 'L01.143'], ['N02.421.143.212', 'N03.540.245.360'], ['N03.219.442.195', 'N03.219.521.710.305.090', 'N04.452.758.745.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['N04.452.822.400'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.7... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Self-paced saccades and saccades to oddball targets in Parkinson's disease. | Patients with Parkinson's disease (PD) manifest difficulty in initiation and execution of movements, particularly when movements are sequential, simultaneous or repetitive. Eye movements are particularly effective in evaluating motor impairments. We utilized a series of saccadic eye movement paradigms to explore the ab... | ['Adult', 'Aged', 'Basal Ganglia', 'Cues', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Middle Aged', 'Neural Pathways', 'Ocular Motility Disorders', 'Orientation', 'Parkinson Disease', 'Photic Stimulation', 'Psychomotor Performance', 'Reaction Time', 'Saccades'] | 16,822,490 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211.200.885.287.249'], ['F02.463.425.234'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.612'], ['C10.228.758', 'C10.292.562', 'C11.590'], ['F01.058.577', 'F02.830.606'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', '... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mass-gathering health research foundational theory: part 1 - population models for mass gatherings. | BACKGROUND: The science underpinning the study of mass-gathering health (MGH) is developing rapidly. Current knowledge fails to adequately inform the understanding of the science of mass gatherings (MGs) because of the lack of theory development and adequate conceptual analysis. Defining populations of interest in the ... | ['Crowding', 'Data Collection', 'Emergency Medical Services', 'Health Planning', 'Health Services Research', 'Humans', 'Mass Behavior', 'Models, Theoretical'] | 25,400,164 | [['F01.145.875.281'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N02.421.297'], ['N03.349', 'N03.706.615.302'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.813.527'], ['E05.599']] | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Juxta-articular Myxoma of the Temporomandibular Joint. | The juxta-articular myxoma represents a benign mesenchymal neoplasm that arises from tissue within or adjacent to a joint space. There have been a number of reported cases involving myxomas of the knee, shoulder, elbow, wrist, and hip. To our knowledge there, however, have been no reported cases of juxta-articular myxo... | ['Cranial Fossa, Middle', 'Female', 'Follow-Up Studies', 'Humans', 'Mandibular Condyle', 'Middle Aged', 'Myxoma', 'Neoplasm Invasiveness', 'Osteotomy', 'Temporal Bone', 'Temporomandibular Joint Disorders'] | 26,594,976 | [['A01.456.830.165', 'A02.835.232.781.750.165'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632.600', 'A14.521.632.600'], ['M01.060.116.630'], ['C04.557.450.565.550'], ['C04.697.645', 'C23.550.727.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Alphavirus capsid proteins self-assemble into core-like particles in insect cells: A promising platform for nanoparticle vaccine development. | The mosquito-borne chikungunya virus (CHIKV) causes arthritic diseases in humans, whereas the aquatic salmonid alphavirus (SAV) is associated with high mortality in aquaculture of salmon and trout. Using modern biotechnological approaches, promising vaccine candidates based upon highly immunogenic, enveloped virus-like... | ['Alphavirus', 'Animals', 'Baculoviridae', 'Capsid Proteins', 'Cell Nucleus', 'Drug Design', 'Epitopes', 'Recombinant Fusion Proteins', 'Sf9 Cells', 'Vaccines, Virus-Like Particle', 'Viral Envelope Proteins', 'Virus Assembly'] | 26,287,127 | [['B04.820.578.875.054'], ['B01.050'], ['B04.280.065', 'B04.525.100'], ['D12.776.964.970.600.550'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D23.050.550'], ['D12.776.828.300'], ['A11.251.210.891'], ['D12.776.828.868.955', 'D20.215.894.865.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolation of Daudi cells with reduced sensitivity to interferon. I. Characterization. | Treatment of Daudi cells with successively increasing concentrations of interferon-alpha resulted in the selection of a cell population which multiplied in the continued presence of 10(4) units/ml of interferon-alpha. A number of clones of interferon-resistant Daudi cells were isolated from this population. Two clones,... | ['Antigens, Viral', 'Cell Division', 'Cell Line', 'Cell Separation', 'Cell Survival', 'Chromosome Aberrations', 'Clone Cells', 'Dose-Response Relationship, Drug', 'Drug Resistance', 'Genetic Variation', 'Humans', 'Interferon Type I', 'Interferon-gamma', 'Karyotyping', 'Time Factors', 'Virus Replication'] | 6,420,510 | [['D23.050.327'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['G04.346'], ['C23.550.210', 'G05.365.590.175'], ['A11.251.353'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984'], ['G05.365'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Target-controlled intravenous anaesthesia with bispectral index monitoring for thoracotomy in a patient with severely impaired left ventricular function. | The anaesthetic management of an elderly patient with severely impaired left ventricular function undergoing thoracotomy and lobectomy is described. Total intravenous anaesthesia (TIVA) with remifentanil and target-controlled infusion of propofol titrated according to the bispectral index (BIS) was used, with thoracic ... | ['Aged', 'Analgesia, Epidural', 'Anesthesia Recovery Period', 'Anesthesia, Intravenous', 'Anesthetics, Intravenous', 'Carcinoma, Squamous Cell', 'Cardiomyopathy, Dilated', 'Electroencephalography', 'Hemodynamics', 'Humans', 'Infusions, Intravenous', 'Intubation, Intratracheal', 'Lung Neoplasms', 'Male', 'Monitoring, In... | 10,853,218 | [['M01.060.116.100'], ['E03.091.080'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E03.155.308'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['E01.370.376.300', 'E01.370.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Higher media multi-tasking activity is associated with smaller gray-matter density in the anterior cingulate cortex. | Media multitasking, or the concurrent consumption of multiple media forms, is increasingly prevalent in today's society and has been associated with negative psychosocial and cognitive impacts. Individuals who engage in heavier media-multitasking are found to perform worse on cognitive control tasks and exhibit more so... | ['Adult', 'Brain', 'Gray Matter', 'Gyrus Cinguli', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Multimedia', 'Psychomotor Performance', 'Regression Analysis', 'Young Adult'] | 25,250,778 | [['M01.060.116'], ['A08.186.211'], ['A08.186.211.168', 'A08.186.854.348'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['J01.897.280.500.633', 'L01.178.820.090.633'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.318.74... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
[ACTIVITY OF Ca2+,Mg(2+)-ATPase OF SARCOPLASMIC RETICULUM AND CONTRACTION STRENGTH OF THE FROG SKELETAL MUSCLES UNDER THE EFFECT OF ORGANOPHOSPHORUS INSECTICIDES]. | The results of an experimental study of organophosphorus insecticides, including pirimiphosmethyl, diazinon and chlorpyrifos caused a decline of the contraction properties in m. tibialis anterior fiber bundles of Rana temporaria, as well as sarcoplasmic reticulum Ca2+, Mg(2+)-ATPase enzymatic activity reduction are out... | ['Adenosine Triphosphate', 'Animals', 'Ca(2+) Mg(2+)-ATPase', 'Chlorpyrifos', 'Diazinon', 'Dose-Response Relationship, Drug', 'Enzyme Assays', 'Female', 'Insecticides', 'Male', 'Muscle Contraction', 'Muscle, Skeletal', 'Organophosphates', 'Rana temporaria', 'Sarcoplasmic Reticulum', 'Tissue Culture Techniques'] | 26,547,965 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.277.040.025.095'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['D02.705.400.625.200', 'D02.705.539.345.200', 'D02.886.300.692.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.196.427'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and optoelectronic properties of 6,12-bis(amino)anthanthrene derivatives. | A series of 6,12-bis(amino) anthanthrene-based conjugated molecules were prepared and characterized using UV-vis and fluorescence spectroscopy and cyclic voltammetry. The absorption spectra and redox potentials of these molecules can be modulated by changing the conjugated moieties linked at the 4 and 10 positions. Mor... | ['Benzopyrans', 'Electrochemical Techniques', 'Molecular Structure', 'Quantum Theory'] | 24,279,378 | [['D03.383.663.283', 'D03.633.100.150'], ['E05.301'], ['G02.111.570', 'G02.466'], ['H01.671.579.800']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Discovery and in Vivo Evaluation of the Potent and Selective PI3Kä Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-... | Optimization of the potency and pharmacokinetic profile of 2,3,4-trisubstituted quinoline, 4, led to the discovery of two potent, selective, and orally bioavailable PI3Kä inhibitors, 6a (AM-0687) and 7 (AM-1430). On the basis of their improved profile, these analogs were selected for in vivo pharmacodynamic (PD) and ef... | ['Animals', 'B-Lymphocytes', 'Class Ia Phosphatidylinositol 3-Kinase', 'Dose-Response Relationship, Drug', 'Drug Discovery', 'Humans', 'Mice', 'Models, Molecular', 'Molecular Structure', 'Phosphoinositide-3 Kinase Inhibitors', 'Protein Kinase Inhibitors', 'Pyridines', 'Quinolines', 'Structure-Activity Relationship'] | 27,411,843 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D08.811.913.696.620.500.100.100.100', 'D08.811.913.696.620.500.200.100.100', 'D12.776.476.162.100'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.295', 'H01.158.703.007.675', 'H01.18... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Pectenotoxin-2 seco acid: a toxin converted from pectenotoxin-2 by the New Zealand Greenshell mussel, Perna canaliculus. | Comparison of pectenotoxin (PTX) profiles of toxic dinoflagellate Dinophysis acuta, Greenshell mussels (Perna canaliculus) and Blue mussels (Mytilus galloprovincialis) collected from Wedge Point, Queen Charlotte Sound, New Zealand was carried out by liquid chromatography-mass spectrometry with turbo-ionspray ionization... | ['Animals', 'Bivalvia', 'Chromatography, Liquid', 'Diarrhea', 'Hydrogen-Ion Concentration', 'Mass Spectrometry', 'Mollusk Venoms', 'Shellfish Poisoning'] | 11,024,491 | [['B01.050'], ['B01.050.500.644.080'], ['E05.196.181.400'], ['C23.888.821.214'], ['G02.300'], ['E05.196.566'], ['D20.888.590', 'D23.946.580.590', 'D23.946.833.590'], ['C25.723.415.792']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recovering root system traits using image analysis exemplified by two-dimensional neutron radiography images of lupine. | Root system traits are important in view of current challenges such as sustainable crop production with reduced fertilizer input or in resource-limited environments. We present a novel approach for recovering root architectural parameters based on image-analysis techniques. It is based on a graph representation of the ... | ['Algorithms', 'Image Processing, Computer-Assisted', 'Lupinus', 'Models, Biological', 'Neutrons', 'Plant Roots', 'Radiography', 'Soil', 'Zea mays'] | 24,218,493 | [['G17.035', 'L01.224.050'], ['L01.224.308'], ['B01.650.940.800.575.912.250.401.571'], ['E05.599.395'], ['G01.249.660.250'], ['A18.400'], ['E01.370.350.700'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.940.800.575.912.250.822.966']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Essential oil composition and antimicrobial activity of wild and cultivated mint timija (Mentha suaveolens subsp. timija (Briq.) Harley), an endemic and threatened medicinal species in Morocco. | The hydro-distilled essential oils obtained from aerial parts of the wild (w) and cultivated (c) mint timija (Mentha suaveolens subsp. timija), an endemic medicinal species of Morocco, have been analyzed by GC-MS and screened for antimicrobial activity. In total, 35 compounds representing more than 98% of the oils were... | ['Anti-Infective Agents', 'Cyclohexane Monoterpenes', 'Drug Evaluation, Preclinical', 'Endangered Species', 'Gas Chromatography-Mass Spectrometry', 'Mentha', 'Menthol', 'Microbial Sensitivity Tests', 'Monoterpenes', 'Morocco', 'Oils, Volatile', 'Plant Components, Aerial'] | 22,838,406 | [['D27.505.954.122'], ['D02.455.426.392.368.367.211', 'D02.455.849.575.157'], ['E05.290.750', 'E05.337.550'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.650.940.800.575.912.250.583.520.483'], ['D02.033.415.510.500.605', 'D0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Rapid speciation analysis of mercury in seawater and marine fish by cation exchange chromatography hyphenated with inductively coupled plasma mass spectrometry. | In this work, a hybrid method for the rapid speciation of mercury compounds by cation exchange chromatographic separation and inductively coupled plasma mass spectrometry (ICP-MS) detection is reported. Effective separation of inorganic mercury (Hg(2+)), methylmercury (MeHg), ethylmercury (EtHg) and phenylmercury (PhHg... | ['Animals', 'Chromatography, Ion Exchange', 'Fishes', 'Marine Biology', 'Mass Spectrometry', 'Mercury', 'Seawater', 'Water Pollutants, Chemical'] | 24,063,982 | [['B01.050'], ['E05.196.181.400.383'], ['B01.050.150.900.493'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500'], ['E05.196.566'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['G16.500.275.725.500'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Orthopedically induced condylar growth in a patient with hemifacial microsomia. | OBJECTIVE: Hemifacial microsomia is a congenital abnormality that causes three-dimensional facial asymmetry, affection of the dental occlusion, and failure of growth of the midface in the growing child. This report outlines orthopedically induced condylar growth in a patient with hemifacial microsomia.PATIENT: A 7-year... | ['Activator Appliances', 'Cephalometry', 'Child', 'Facial Asymmetry', 'Female', 'Follow-Up Studies', 'Humans', 'Malocclusion, Angle Class II', 'Mandibular Condyle', 'Orthodontic Appliance Design', 'Osteogenesis'] | 14,577,808 | [['E06.658.453.560.100', 'E06.658.453.578.100'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['C23.300.505'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494.630'], ['A02.835... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CA1 pyramid-pyramid connections in rat hippocampus in vitro: dual intracellular recordings with biocytin filling. | In adult rat hippocampus, simultaneous intracellular recordings from 989 pairs of CA1 pyramidal cells revealed nine monosynaptic, excitatory connections. Six of these pairs were sufficiently stable for electrophysiological analysis. Mean excitatory postsynaptic potential amplitude recorded at a postsynaptic membrane po... | ['2-Amino-5-phosphonovalerate', 'Animals', 'Electric Stimulation', 'Evoked Potentials', 'Excitatory Amino Acid Agonists', 'Excitatory Amino Acid Antagonists', 'Hippocampus', 'Lysine', 'Male', 'Membrane Potentials', 'N-Methylaspartate', 'Pyramidal Cells', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate'... | 8,895,869 | [['D12.125.070.950.100', 'D12.125.740.025'], ['B01.050'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.125.068.555', 'D12.125.095.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of Alzheimer's disease progression based on clinical dementia rating scale with missing responses and covariates. | In clinical trials, patient's disease severity is usually assessed on a Likert-type scale. Patients, however, may miss one or more follow-up visits (non-monotone missing). The statistical analysis of non-Gaussian longitudinal data with non-monotone missingness is difficult to handle, particularly when both response and... | ['Alzheimer Disease', 'Data Interpretation, Statistical', 'Dementia', 'Disease Progression', 'Humans', 'Longitudinal Studies', 'Mental Status and Dementia Tests', 'Monte Carlo Method', 'Organ Size', 'Severity of Illness Index'] | 29,173,033 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C10.228.140.380', 'F03.615.400'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Association between the -174 G/C polymorphism of the interleukin-6 gene and myocardial infarction risk: a meta-analysis. | Numerous studies have evaluated the association between the -174 G/C polymorphism in the interleukin-6 gene (IL6) and myocardial infarction (MI) risk. However, the results from the published studies are inconclusive. The aim of this meta-analysis was to determine whether the IL6 -174 G/C polymorphism is associated with... | ['Alleles', 'Case-Control Studies', 'Ethnic Groups', 'European Continental Ancestry Group', 'Genetic Predisposition to Disease', 'Humans', 'Interleukin-6', 'Myocardial Infarction', 'Polymorphism, Single Nucleotide', 'Risk Factors'] | 27,706,582 | [['G05.360.340.024.340.030'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.686.754', 'N01.224.317'], ['M01.686.508.400'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.4... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical effect of the extract of TCM Fructus akebiae combined with ursodeoxycholic acid on nonalcoholic fatty liver disease. | .Fructus akebiae extract (FAE) is a commonly used drug in the clinical treatment of liver cancer. FAE has many pharmacological activities, such as liver protection, anti-tumor, spasmolysis, pain relief and antifungal activity. Its clinical application is extensive, so far no toxic reports have been reported, and new dr... | ['Cholagogues and Choleretics', 'Drug Therapy, Combination', 'Drugs, Chinese Herbal', 'Female', 'Humans', 'Liver', 'Liver Function Tests', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Tomography, X-Ray Computed', 'Ultrasonography', 'Ursodeoxycholic Acid'] | 30,852,481 | [['D27.505.954.483.508'], ['E02.319.310'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.372.460'], ['M01.060.116.630'], ['C06.552.241.519'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.37... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
HLA alleles, especially amino-acid signatures of HLA-DPB1, might contribute to the molecular pathogenesis of early-onset autoimmune thyroid disease. | The major histocompatibility complex region has been suggested to play an important role in the development of autoimmune thyroid disease (AITD). In this study, we investigated the associations of human leukocyte antigen (HLA) alleles and amino acid variants of HLA with early-onset AITD. HLA class I and class II genes ... | ['Adolescent', 'Adult', 'Age of Onset', 'Alleles', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Female', 'Gene Expression', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Graves Disease', 'HLA-DP beta-Chains', 'Haplotypes', 'Hashimoto Disease', 'Humans', 'Male', 'Polymorphism, Genetic'] | 31,091,281 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['G05.360.340.024.340.030'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['G05.297'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['C11.675.349.500', 'C19.... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional characterization of two members of histidine phosphatase superfamily in Mycobacterium tuberculosis. | BACKGROUND: Functional characterization of genes in important pathogenic bacteria such as Mycobacterium tuberculosis is imperative. Rv2135c, which was originally annotated as conserved hypothetical, has been found to be associated with membrane protein fractions of H37Rv strain. The gene appears to contain histidine ph... | ['Cloning, Molecular', 'Enzyme Stability', 'Escherichia coli', 'Gene Expression', 'Histidine', 'Hydrogen-Ion Concentration', 'Kinetics', 'Mycobacterium tuberculosis', 'Phosphoric Monoester Hydrolases', 'Recombinant Proteins'] | 24,330,471 | [['E05.393.220'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['D12.125.072.329', 'D12.125.142.308'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D08.811.277.352.650'], ['D12.776.828']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis. | Fibrosis of the liver and its end-stage, cirrhosis, represent major health problems worldwide. In these fibrotic conditions, activated fibroblasts and hepatic stellate cells display a net deposition of collagen. This collagen deposition is a major factor leading to liver dysfunction, thus making it crucially important ... | ['Animals', 'Antibodies, Blocking', 'Cell Line', 'Collagen', 'Endocytosis', 'Female', 'Fibroblasts', 'Hepatic Stellate Cells', 'Humans', 'Liver Cirrhosis, Experimental', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred Strains', 'Mice, Knockout', 'Receptors, Cell Surface', 'Up-Regulation'] | 22,294,280 | [['B01.050'], ['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['A11.251.210'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G04.417'], ['A11.329.228'], ['A11.561'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630.467', 'C23.550.355.412.467', 'E05.598.500.46... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma. | AIMS: Microglandular adenosis (MGA) is a rare breast lesion, which has long been considered to be hyperplastic. However, atypical forms of MGA (AMGA) and invasive carcinomas arising in the background of MGA are recorded. Recent studies have suggested that MGA may be a non-obligate precursor of invasive carcinomas that ... | ['Adenoma', 'Aged', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Diagnosis, Differential', 'Female', 'Fibrocystic Breast Disease', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Oligonucleotide Array Sequence Analysis'] | 19,922,592 | [['C04.557.470.035'], ['M01.060.116.100'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['E01.171'], ['C17.800.090.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.22... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular cloning and sequence analysis of rat bradykinin B2 receptor gene. | The bradykinin B2 receptor mediates the effect of kinin. In order to understand the structure and regulation of its expression, we have cloned and sequenced the gene encoding the rat bradykinin B2 receptor and its 5' flanking region from a rat genomic library. The B2 receptor gene spans 7.3 kb in length and contains th... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'DNA Probes', 'DNA, Complementary', 'Genomic Library', 'Kinins', 'Molecular Sequence Data', 'Rats', 'Receptors, Bradykinin', 'Sequence Analysis, DNA'] | 8,086,459 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.360.325.425', 'G05.360.340... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The evolution of metabolic networks of E. coli. | BACKGROUND: Despite the availability of numerous complete genome sequences from E. coli strains, published genome-scale metabolic models exist only for two commensal E. coli strains. These models have proven useful for many applications, such as engineering strains for desired product formation, and we sought to explor... | ['Escherichia coli', 'Evolution, Molecular', 'Genome, Bacterial', 'Metabolic Networks and Pathways', 'Models, Biological', 'Phylogeny', 'Salmonella'] | 22,044,664 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.358.207'], ['G03.493'], ['E05.599.395'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B03.440.450.425.800', 'B03.660.250.150.710']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Specific association of HLA-DR4 with increased prevalence and level of insulin autoantibodies in first-degree relatives of patients with type I diabetes. | First-degree relatives of patients with insulin-dependent (type I) diabetes (n = 264 from 106 families) were evaluated with HLA typing and determination of competitive insulin autoantibodies (CIAAs) and islet cell autoantibodies (ICAs). The levels of CIAAs in 30 relatives exceeded our upper limit of normal (greater tha... | ['Autoantibodies', 'Diabetes Mellitus, Type 1', 'Family', 'Female', 'HLA Antigens', 'HLA-DR3 Antigen', 'HLA-DR4 Antigen', 'Histocompatibility Testing', 'Humans', 'Insulin Antibodies', 'Islets of Langerhans', 'Male', 'Nuclear Family', 'Pedigree', 'Prevalence'] | 2,040,387 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['F01.829.263', 'I01.880.853.150'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.509.400.440.400.030', 'D12.776.543.550.440.400.440.400.030', 'D23.0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Screening and identification of the nucleic acid aptamers in nasopharyngeal carcinoma. | To screen the nucleic acid aptamers of the EB virus-positive nasopharyngeal carcinoma cells, we used SELEX technology and synthesized in vitro a 78-nucleotide random DNA library. We used normal nasopharyngeal epithelial cells and EB virus-positive low differentiated nasopharyngeal carcinoma cells as target to conduct 1... | ['Aptamers, Nucleotide', 'Base Sequence', 'Carcinoma', 'Cell Line, Tumor', 'Epstein-Barr Virus Infections', 'Gene Library', 'Herpesvirus 4, Human', 'Humans', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'SELEX Aptamer Technique', 'Sequence Analysis, DNA'] | 24,391,032 | [['D13.695.578.424.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200'], ['A11.251.210.190', 'A11.251.860.180'], ['C01.925.256.466.313', 'C01.925.928.313'], ['G05.360.325'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Diabetes and Overall Survival among Breast Cancer Patients in the U.S. Military Health System. | Background: Although research suggests that type II diabetes mellitus (DM-2) is associated with overall and breast cancer-specific decreased survival, most prior studies of breast cancer survival investigated the effect of preexisting DM-2 without assessing the effect of DM-2 diagnosed at or after breast cancer diagnos... | ['Breast Neoplasms', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Military Personnel', 'Proportional Hazards Models', 'Registries', 'United States'] | 29,097,445 | [['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
ncd and kinesin motor domains interact with both alpha- and beta-tubulin. | Motor domains of the Drosophila minus-end-directed microtubule (MT) motor protein ncd, were found to saturate microtubule binding sites at a stoichiometry of approximately one motor domain per tubulin dimer. To determine the tubulin subunit(s) involved in binding to ncd, mixtures of ncd motor domain and MTs were treate... | ['Animals', 'Blotting, Western', 'Cross-Linking Reagents', 'Drosophila', 'Drosophila Proteins', 'Electrophoresis, Polyacrylamide Gel', 'Ethyldimethylaminopropyl Carbodiimide', 'Kinesin', 'Kinetics', 'Microtubule Proteins', 'Protein Binding', 'Recombinant Proteins', 'Tubulin'] | 7,597,061 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D27.720.470.410.210'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.491.203.425'], ['D08.811.277.040.025.193.500', 'D12.776.220.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Co-morbidity: exploring the clinical overlap between pneumonia and diarrhoea in a hospital in Dhaka, Bangladesh. | BACKGROUND: There is limited information on risk factors for pneumonia and pneumonia-related deaths in children who also have diarrhoea.AIM: To identify risk factors for the above in order to improve strategies for case management and to develop appropriate public health messages.METHODS: All children under 5 years of... | ['Bangladesh', 'Child, Preschool', 'Cohort Studies', 'Comorbidity', 'Diarrhea', 'Female', 'Hospitals', 'Humans', 'Infant', 'Male', 'Pneumonia', 'Prospective Studies'] | 22,041,465 | [['Z01.252.245.131'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.888.821.214'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['E05.3... | ['Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
ENALAPRIL EFFECT ON THE STATE OF NITROGEN OXIDE SYSTEM AND PROOXIDANT-ANTIOXIDANT BALANCE IN BRAIN UNDER CONDITIONS OF BLOCKADE OF CENTRAL CHOLINERGIC SYSTEM. | One of the most important medical-social issues today is the search for new pathogenic directions in pharmacological prevention and treatment of neurodegenerative diseases of the central nervous system. Objective: to investigate enalapril effect on the indices of the nitrogen oxide system and prooxidant-antioxidant bal... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Antihypertensive Agents', 'Antioxidants', 'Brain', 'Cerebral Cortex', 'Cholinergic Agents', 'Enalapril', 'Hippocampus', 'Male', 'Neurodegenerative Diseases', 'Nitrogen Oxides', 'Rats', 'Scopolamine'] | 30,958,304 | [['D27.505.519.389.745.085'], ['B01.050'], ['D27.505.954.411.162'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['D27.505.519.625.120', 'D27.505.696.577.120'], ['D12.644.456.345.360'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['C10.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monoclonal and oligoclonal gammopathies in heart-transplant recipients. | Immunoglobulin abnormalities in serum from 76 heart-transplant recipients were examined by cellulose acetate and agarose gel electrophoresis. Monoclonal components were typed by immunofixation. IgG, IgA, and IgM and total kappa and lambda light chains were quantified by immunonephelometry. We confirm that both monoclon... | ['Adult', 'Electrophoresis, Agar Gel', 'Electrophoresis, Cellulose Acetate', 'Female', 'Heart Transplantation', 'Humans', 'Immunoglobulin Heavy Chains', 'Immunoglobulin Light Chains', 'Immunoglobulin kappa-Chains', 'Immunoglobulin lambda-Chains', 'Male', 'Middle Aged', 'Paraproteinemias'] | 1,907,894 | [['M01.060.116'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.196.401.200', 'E05.301.300.200'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.705.500', 'D12.776.124.790.651.705.500', 'D12.776.377.715.548.705.500'], ['D12.776.124.486.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increase in extracellular glutamate caused by reduced cerebral perfusion pressure and seizures after human traumatic brain injury: a microdialysis study. | OBJECT: To determine the extent and duration of change in extracellular glutamate levels after human traumatic brain injury (TBI), 17 severely brain injured adults underwent implantation of a cerebral microdialysis probe and systematic sampling was conducted for 1 to 9 days postinjury.METHODS: A total of 772 hourly mic... | ['Adult', 'Biomarkers', 'Blood Pressure', 'Brain Injuries', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Extracellular Space', 'Female', 'Glutamic Acid', 'Humans', 'Male', 'Microdialysis', 'Middle Aged', 'Prospective Studies', 'Retrospective Studies', 'Wounds and Injuries'] | 9,833,824 | [['M01.060.116'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['A10.082.500', 'A11.284.295'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Openness of patients' reporting with use of electronic records: psychiatric clinicians' views. | OBJECTIVES: Improvements in electronic health record (EHR) system development will require an understanding of psychiatric clinicians' views on EHR system acceptability, including effects on psychotherapy communications, data-recording behaviors, data accessibility versus security and privacy, data quality and clarity,... | ['Adult', 'Attitude to Health', 'Computer Security', 'Confidentiality', 'Disclosure', 'Electronic Health Records', 'Female', 'Health Care Surveys', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', "Practice Patterns, Physicians'", 'Psychiatry', 'Psychotherapeutic Processes', 'Tennessee'] | 20,064,802 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['L01.224.134', 'N04.452.910.200'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Chromosomal localization of the major and 5S rRNA genes in the European eel (Anguilla anguilla). | The major (18S, 5.8S, and 28S) and 5S rRNA genes have been mapped by double fluorescent in situ hybridization to European eel metaphase chromosomes. The major rRNA genes were localized to a submetacentric pair of chromosomes that showed a consistent size polymorphism among the individuals studied. The 5S rRNA genes wer... | ['Anguilla', 'Animals', 'Chromosome Mapping', 'DNA, Ribosomal', 'Genes', 'In Situ Hybridization, Fluorescence', 'Lymphocytes', 'Metaphase', 'RNA, Ribosomal, 18S', 'RNA, Ribosomal, 28S', 'RNA, Ribosomal, 5S'] | 8,646,885 | [['B01.050.150.900.493.338.282'], ['B01.050'], ['E05.393.183'], ['D13.444.308.475'], ['G05.360.340.024.340'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['A11.118.637.555.567', 'A15.145.2... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Application of a deep learning algorithm for detection and visualization of hip fractures on plain pelvic radiographs. | OBJECTIVE: To identify the feasibility of using a deep convolutional neural network (DCNN) for the detection and localization of hip fractures on plain frontal pelvic radiographs (PXRs). Hip fracture is a leading worldwide health problem for the elderly. A missed diagnosis of hip fracture on radiography leads to a dism... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Deep Learning', 'False Negative Reactions', 'Feasibility Studies', 'Female', 'Hip Fractures', 'Humans', 'Male', 'Middle Aged', 'Neural Networks, Computer', 'Prognosis', 'ROC Curve', 'Radiographic Image Interpretation, Computer-Assisted', 'Radiography, Abdominal', 'S... | 30,937,588 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['G17.035.250.500.250', 'G17.485.500', 'L01.224.050.375.530.250', 'L01.224.050.375.605.500'], ['E01.354.340'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['C26.404.061.425', 'C26.531.750', ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Productivity and salinity structuring of the microplankton revealed by comparative freshwater metagenomics. | Little is known about the diversity and structuring of freshwater microbial communities beyond the patterns revealed by tracing their distribution in the landscape with common taxonomic markers such as the ribosomal RNA. To address this gap in knowledge, metagenomes from temperate lakes were compared to selected marine... | ['Archaea', 'Bacteria', 'Data Mining', 'Fresh Water', 'Lakes', 'Metabolic Networks and Pathways', 'Metagenome', 'Metagenomics', 'Molecular Sequence Annotation', 'Phylogeny', 'RNA, Ribosomal', 'Salinity', 'Seawater', 'Sequence Analysis, DNA'] | 24,118,837 | [['B02'], ['B03'], ['L01.313.500.750.280.199', 'L01.470.625'], ['G16.500.275.280', 'N06.230.232'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['G03.493'], ['G05.360.340.550'], ['H01.158.273.343.350.261'], ['E05.393.760.479', 'L01.453.245.667.580'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.73... | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Preoperative templating before spinal fusion using a fluoroscopic multiplanar imaging system is as accurate as CT scan and uses substantially less radiation. | BACKGROUND: Many surgeons utilize preoperative multiplanar imaging for surgical planning before fusion surgery using pedicle screw instrumentation. Computed tomographic (CT) scan is often used but limited by non-weight-bearing images and high-ionizing radiation. The purpose of this study was to compare pedicle length a... | ['Bone Screws', 'Cadaver', 'Child', 'Fluoroscopy', 'Humans', 'Lumbar Vertebrae', 'Observer Variation', 'Preoperative Care', 'Radiation Dosage', 'Spinal Fusion', 'Tomography, X-Ray Computed'] | 23,147,634 | [['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['C23.550.260.224'], ['M01.060.406'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E02.760.795', 'E04.604.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social networks and health of older people living in sheltered housing. | Eighty-seven residents from three sheltered accommodation schemes for people over 60 years, were interviewed about: their physical and mental health, social networks, social support, decision to move in, and how they found living in sheltered housing. Twenty-four percent had a diagnosis of depression and 8% dementia, b... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Dementia', 'Depressive Disorder', 'Female', 'Health Status', 'Housing for the Elderly', 'Humans', 'Male', 'Social Support'] | 12,425,771 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380', 'F03.615.400'], ['F03.600.300'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['J03.340.260', 'N01.224.791.400.410', 'N06.230.150.360.260'], ['B01.050.150.900.649.313.98... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Establishing a transplant coordinator-led living kidney donor follow-up clinic. | BACKGROUND: The long-term risks of renal failure and hypertension are statistically low for living kidney donors as a group, but can have serious consequences for the individual.OBJECTIVES: To describe the experience with a transplant coordinator-led living donor follow-up clinic.METHOD: Living kidney donors are review... | ['Aftercare', 'Ambulatory Care Facilities', 'Continuity of Patient Care', 'Follow-Up Studies', 'Humans', 'Kidney Transplantation', 'Living Donors', 'Nephrectomy', 'Nurse Clinicians', 'Nursing Audit', 'Nursing Evaluation Research', 'Organizational Objectives', 'Patient Satisfaction', 'Program Development', 'Program Eval... | 12,841,521 | [['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['N02.278.035'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
IL6 gene allele-specific C/EBPá-binding activity affects the development of HBV infection through modulation of Th17/Treg balance. | Interleukin-6 (IL-6) has an important role in the pathogenesis of chronic viral hepatitis and related liver diseases. Although host genetics associated with the response to anti-viral treatment have been reported, little is known about the relationship between IL6 genetic polymorphisms and the outcome of hepatitis B vi... | ['Alanine Transaminase', 'CCAAT-Enhancer-Binding Proteins', 'Genetic Predisposition to Disease', 'HIV Infections', 'Hepatitis B', 'Humans', 'Interleukin-6', 'Polymorphism, Single Nucleotide', 'Promoter Regions, Genetic', 'T-Lymphocytes, Regulatory', 'Th17 Cells', 'Viral Load'] | 26,447,433 | [['D08.811.913.477.700.100'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['C23.550.291.687.500', 'G05.380.355'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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