Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Avian leucocyte common antigens: molecular weight determination and flow cytometric analysis using new monoclonal antibodies. | New leucocyte common antigens expressed on all the normal chicken leucocytes have been characterized using two monoclonal antibodies designated as K-11 and K-55. These monoclonal antibodies stained virtually 100% of the leucocytes derived from various lymphoid organs including the spleen, thymus, bursa of Fabricius, ca... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, CD', 'Blotting, Western', 'Cell Line', 'Chickens', 'Epitopes', 'Female', 'Flow Cytometry', 'Histocompatibility Antigens', 'Leukocyte Common Antigens', 'Lymphoid Tissue', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Molecular Weight', 'Phosphoprotein ... | 1,719,691 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dysregulation of gene expression in ABCC6 knockdown HepG2 cells. | ABCC6 protein is an ATP-dependent transporter that is mainly found in the basolateral plasma membrane of hepatocytes. ABCC6 deficiency is the primary cause of several forms of ectopic mineralization syndrome. Mutations in the human ABCC6 gene cause pseudoxanthoma elasticum (PXE), an autosomal recessive disease characte... | ["5'-Nucleotidase", 'Calcinosis', 'Carrier Proteins', 'GPI-Linked Proteins', 'Gene Expression', 'Gene Expression Regulation, Enzymologic', 'Gene Knockdown Techniques', 'Hep G2 Cells', 'Humans', 'Multidrug Resistance-Associated Proteins'] | 25,169,437 | [['D08.811.277.352.650.600.600'], ['C18.452.174.130'], ['D12.776.157'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'], ['G05.297'], ['G05.308.320'], ['E05.393.335.500'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.100.304', 'D12.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prognostic factors related to mortality in newborns with jejunoileal atresia]. | BACKGROUND: Jejuno-ileal atresia is one of the main causes of intestinal obstruction in neonates. The origin is vascular accidents in the fetal intestine. It is an entity that requires early and specialist management.OBJECTIVE: to know the factors related to mortality in neonates with jejunoileal atresia.METHODS: Case-... | ['Abnormalities, Multiple', 'Anastomosis, Surgical', 'Birth Order', 'Case-Control Studies', 'Catheter-Related Infections', 'Comorbidity', 'Female', 'Humans', 'Ileostomy', 'Ileum', 'Infant, Newborn', 'Intestinal Atresia', 'Intestinal Perforation', 'Jejunum', 'Male', 'Peritonitis', 'Pneumoperitoneum', 'Polyhydramnios', '... | 23,374,382 | [['C16.131.077'], ['E04.035'], ['F01.829.263.132', 'I01.240.361.160', 'N01.224.361.160', 'N06.850.505.400.400.160'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.195'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Intakes of PUFAs were inversely associated with plasma C-reactive protein 12 years later in a middle-aged population with vitamin E intake as an effect modifier. | Although n-3 (ù-3) polyunsaturated fatty acids (PUFAs) are considered anti-inflammatory components, the role of dietary n-6 PUFAs in inflammation remains controversial. Some mechanistic evidence suggests vitamin E as a potential effect modifier in the relationship between PUFAs and inflammation. Our objectives were to ... | ['Adult', 'Anthropometry', 'Anti-Inflammatory Agents', 'C-Reactive Protein', 'Diet', 'Diet Records', 'Double-Blind Method', 'Fatty Acids, Omega-3', 'Fatty Acids, Omega-6', 'Female', 'Humans', 'Inflammation', 'Life Style', 'Logistic Models', 'Male', 'Middle Aged', 'Motor Activity', 'Nutrition Assessment', 'Socioeconomic... | 24,027,184 | [['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D27.505.954.158'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['G07.203.650.240'], ['N04.452.859.360'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D10.212.302.380.410', 'D10.25... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[From "wet caries" to controllable complication. History of post-traumatic and postoperative osteitis]. | In former times treatment of osteomyelitis was based on very few surgical principles such as incision of the infected region, debridement with sequestrectomy, and continuous drainage to prevent superficial closing of the wound. There were no rules for asepsis, anesthesia, and microbiology in the treatment of bone infec... | ['Anti-Bacterial Agents', 'Bone and Bones', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Osteitis', 'Surgical Wound Infection'] | 15,004,670 | [['D27.505.954.122.085'], ['A02.835.232', 'A10.165.265'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.680'], ['C01.947.692', 'C23.550.767.925']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indoor environment is a public health issue. Conference on indoor air quality and health July 4-8, 1993 Helsinki, Finland, Press Bulletin. | No one today is in any doubt that the indoor environment can constitute a real health hazard if buildings are not properly designed, constructed and maintained. The 690 papers presented at the Sixth International Conference on Indoor Air Quality and Health held in Helsinki, Finland, are an indisputable proof of this. T... | ['Air Pollution, Indoor', 'Global Health', 'Health Policy', 'Humans', 'Public Health'] | 7,911,696 | [['N06.850.460.100.080'], ['H02.403.371', 'N01.400.337'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Nutritional status and its correlates among tribal children of Melghat, central India. | OBJECTIVE: To find out the magnitude and epidemiological determinants of malnutrition among 0-6 y tribal children.METHODS: A community based cross sectional study was done in the villages of Melghat in central India. The information of 540 children in the age group 0-6 y was collected. The newly developed WHO growth st... | ['Anthropometry', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Humans', 'India', 'Infant', 'Infant, Newborn', 'Male', 'Malnutrition', 'Nutritional Status', 'Prevalence', 'Risk Factors'] | 24,647,871 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.703'], ['M01.060.703.520'], ['C18.654.521'], ['G07.203.650.650', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The differential development of adolescent alcohol expectancies may predict adult alcoholism. | To investigate changes in adolescent's alcohol expectancies as a function of increasing age and drinking experience, we compared the degree to which 12-14, 15-16, and 17-19 year old adolescents from normal seventh to twelfth grade classrooms (N = 1580) affirmed items comprising seven alcohol-expectancy scales. Results ... | ['Adolescent', 'Adult', 'Age Factors', 'Alcoholism', 'Attitude', 'Child', 'Humans', 'Psychology, Adolescent'] | 4,083,106 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.628.065']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels. | Peripheral artery disease (PAD) is characterized by vessel occlusion and ischemia in the limbs. Treatment for PAD with surgical interventions has been showing limited success. Moreover, recent clinical trials with treatment of angiogenic growth factors proved ineffective as increased angiogenesis triggered severe infla... | ['Angiogenesis Inducing Agents', 'Animals', 'Anti-Inflammatory Agents', 'Cell Line', 'Drug Carriers', 'Human Umbilical Vein Endothelial Cells', 'Inflammation', 'Injections', 'Matrix Metalloproteinase 9', 'Matrix Metalloproteinase Inhibitors', 'Mice', 'Neovascularization, Physiologic', 'Oligopeptides', 'Peripheral Arter... | 25,154,665 | [['D27.505.696.377.077.077'], ['B01.050'], ['D27.505.954.158'], ['A11.251.210'], ['D26.255.260', 'E02.319.300.380'], ['A11.436.275.682'], ['C23.550.470'], ['E02.319.267.530'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252.445', 'D08.811.277.656.300.480.525.700.350', 'D08.811.277.656.675.374.205.360',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis. | Acquired immunodeficiency syndrome (AIDS)-associated dementia is often characterized by chronic inflammation, with infected macrophage infiltration of the CNS resulting in the production of human immunodeficiency virus type 1 (HIV-1) products, including tat, and neurotoxins that contribute to neuronal loss. In addition... | ['AIDS Dementia Complex', 'Apoptosis', 'Astrocytes', 'Cells, Cultured', 'Chemokine CCL2', 'Chemokine CCL5', 'Coculture Techniques', 'Dizocilpine Maleate', 'Excitatory Amino Acid Antagonists', 'Gene Products, tat', 'Glutamic Acid', 'Humans', 'N-Methylaspartate', 'Neurons', 'Neuroprotective Agents', 'Receptors, N-Methyl-... | 12,753,088 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['G04.146.954.035'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.99... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acquisition of native conformation of ribosomal 5S ribonucleic acid from Escherichia coli. Hydrodynamic and spectroscopic studies on the unfolding and refolding of ribonucleic acid. | In a continuing effort to decipher the molecular mechanism of ribosome self-assembly [e.g., Dunn, J. M., & Wong, K.-P. (1979) Biochemistry 18, 4380-4385], the mechanism of folding of 5S RNA was investigated by unfolding and refolding studies using several physical techniques including circular dichroism (CD), UV absorp... | ['Circular Dichroism', 'Edetic Acid', 'Escherichia coli', 'Magnesium', 'Nucleic Acid Conformation', 'RNA, Ribosomal', 'Ribosomes', 'Spectrophotometry, Ultraviolet', 'Temperature', 'Urea'] | 6,807,343 | [['E05.196.867.151'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735.686'], ['A11.284.430.214.190.875.811'], ['E05.196.712.726.802', 'E05.196.867.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The synthesis and evaluation of new butadiene derivatives as tubulin polymerization inhibitors. | A series of new butadiene derivatives was synthesized and evaluated as tubulin polymerization inhibitors for the treatment of cancer. The optimal butadiene derivative, 9a, exhibited IC50 values of 0.056-0.089ìM for five human cancer cell lines. This paper included a mechanistic study of the antiproliferative activity, ... | ['Antineoplastic Agents', 'Apoptosis', 'Butadienes', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Proliferation', 'HeLa Cells', 'Humans', 'Neoplasms', 'Tubulin Modulators'] | 28,404,525 | [['D27.505.954.248'], ['G04.146.954.035'], ['D02.455.326.271.665.146.240'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['D27.505.519.593.249.500'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Too much nephrology? The CKD epidemic is real and concerning. A PRO view. | After decades of Babylonian confusion, we finally have a clear, uniform and widely accepted definition of chronic kidney disease (CKD). Based on evidence, and in accordance with other diseases, this definition is independent of age. This has made it possible to study the relevance and prevalence of CKD. We now know tha... | ['Epidemics', 'Humans', 'Nephrology', 'Prevalence', 'Renal Insufficiency, Chronic'] | 30,418,646 | [['N06.850.290.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.580'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['C12.777.419.780.750', 'C13.351.968.419.780.750']] | ['Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Activity of single agent vinorelbine in pretreated non-Hodgkin's lymphoma. | BACKGROUND: To assess the activity of single agent vinorelbine in pretreated non Hodgkin's lymphoma.PATIENTS AND METHODS: Twenty-three pretreated patients with non-Hodgkin's lymphoma (14 intermediate-high grade, nine low-grade) were treated with vinorelbine 30 mg/m2/week for six months or up to four doses after achievi... | ['Adult', 'Aged', 'Antineoplastic Agents, Phytogenic', 'Humans', 'Lymphoma, Non-Hodgkin', 'Middle Aged', 'Salvage Therapy', 'Vinblastine', 'Vinorelbine'] | 9,006,750 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248.179'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['E02.895'], ['D03.132.436.681.827.650', 'D03.633.100.473.402.681.827.650', 'D03.633.100.496.500.500.681.827.650'], ['D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relations between the expression of p53, c-erbB-2, Ki-67 and HPV infection in cervical carcinomas and cervical dysplasias. | BACKGROUND: The analysis of mutual relations between HPV infection and the expression of cancer gene products and proliferative activity in cervical carcinomas and dysplasias.MATERIALS AND METHODS: The expression of p53, c-erbB-2 oncoproteins and proliferative activity (Ki-67) was evaluated immunohistochemically in 41 ... | ['Cervical Intraepithelial Neoplasia', 'Female', 'Humans', 'Ki-67 Antigen', 'Papillomaviridae', 'Papillomavirus Infections', 'Receptor, ErbB-2', 'Tumor Suppressor Protein p53', 'Tumor Virus Infections', 'Uterine Cervical Dysplasia', 'Uterine Cervical Neoplasms'] | 11,396,132 | [['C04.557.470.200.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660.625.500', 'D23.050.290.500', 'D23.101.140.400'], ['B04.280.210.655', 'B04.613.204.655'], ['C01.925.256.650', 'C01.925.928.725'], ['D08.811.913.696.620.682.725.400.009.400', 'D12.776.543.750.630.009.400', 'D12.776.543.750.750.40... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Tocolytic treatment with fenoterol. I. Prospective study of the effect of tocolysis on the condition of the newborn infant and early childhood development up to 4 years of age]. | From 1976 to 1979 a prospective study was run at the Women's Hospital of Heidelberg in which every women was registered who attended the hospital before the 20th week of pregnancy. After delivery the infants' development was followed up to four years. During this time 404 women received fenoterol and 74 of them had pre... | ['Birth Weight', 'Child Development', 'Child, Preschool', 'Female', 'Fenoterol', 'Fetal Growth Retardation', 'Follow-Up Studies', 'Gestational Age', 'Humans', 'Infant', 'Infant, Newborn', 'Obstetric Labor, Premature', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies', 'Risk Factors'] | 2,711,726 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['D02.033.100.291.465.300', 'D02.092.063.291.465.300', 'D02.092.311.660.300', 'D02.455.426.559.389.657.166.175.660.300'], ['C... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Wear behavior of pressable lithium disilicate glass ceramic. | This article reports effects of surface preparation and contact loads on abrasive wear properties of highly aesthetic and high-strength pressable lithium disilicate glass-ceramics (LDGC). Abrasive wear testing was performed using a pin-on-disk device in which LDGC disks prepared with different surface finishes were aga... | ['Ceramics', 'Dental Porcelain', 'Glass', 'Stress, Mechanical'] | 25,980,530 | [['J01.637.153'], ['D25.339.376', 'J01.637.051.339.376', 'J01.637.153.377'], ['J01.637.437'], ['G01.374.835']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
3D-QSAR and molecular modeling studies on 2,3-dideoxy hexenopyranosid-4-uloses as anti-tubercular agents targeting alpha-mannosidase. | Ligand-based and structure-based methods were applied in combination to exploit the physicochemical properties of 2,3-dideoxy hex-2-enopyranosid-4-uloses against Mycobacterium tuberculosis H37Rv. Statistically valid 3D-QSAR models with good correlation and predictive power were obtained with CoMFA steric and electrosta... | ['Antitubercular Agents', 'Deoxy Sugars', 'Humans', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Mycobacterium tuberculosis', 'Quantitative Structure-Activity Relationship', 'Tuberculosis', 'alpha-Mannosidase'] | 25,727,263 | [['D27.505.954.122.085.255'], ['D09.254'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['G02.111.830.500', 'G07.690.773.997.500'], ['C01.150.252.410.040... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Endothelial ultrastructure of myocardium microvessels affected by various methods of artificial hypothermia]. | A comparative analysis of the endothelial ultrastructure of myocardium microvessels affected by various methods of artificial hypothermia was carried out. Tissue samples were harvested in children with a congenital ventricular septum defect after cooling the whole body under the conditions of hypothermic artificial cir... | ['Cell Count', 'Child, Preschool', 'Coronary Vessels', 'Endothelium, Vascular', 'Humans', 'Hypothermia, Induced', 'Infant', 'Organelles', 'Perfusion', 'Pinocytosis', 'Time Factors'] | 17,338,258 | [['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['M01.060.406.448'], ['A07.015.114.269', 'A07.015.908.194'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['M01.060.703'], ['A11.284.430.214.190.875'], ['E05.680'], ['G04.417.370'], ['G01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rickettsiaceae and Anaplasmataceae infections in Ixodes ricinus ticks from urban and natural forested areas of Poland. | BACKGROUND: Ixodes ricinus is a major vector for a range of microbial pathogens and the most prevalent and widely distributed tick species on the European continent, occurring in both natural and urban habitats. Nevertheless, little is known about the relative density of ticks in these two ecologically distinct habitat... | ['Anaplasmataceae', 'Anaplasmataceae Infections', 'Animals', 'Base Sequence', 'DNA, Bacterial', 'DNA, Ribosomal', 'Female', 'Forests', 'Humans', 'Ixodes', 'Male', 'Molecular Sequence Data', 'Nymph', 'Phylogeny', 'Poland', 'Polymorphism, Genetic', 'Prevalence', 'Rickettsiaceae', 'Rickettsiaceae Infections', 'Sequence An... | 24,661,311 | [['B03.440.664.750', 'B03.660.050.783.500'], ['C01.150.252.400.054'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['D13.444.308.475'], ['G16.500.275.157.437', 'N06.230.124.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.131.166.132.832.400.425'], ['... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Similar synapse density in layer IV columns of the primary somatosensory cortex of transgenic mice with different brain size: implications for mechanisms underlying the differential allocation of cortical space. | The relative dimension of the areas constituting the cerebral cortex differs greatly in the brains of different mammalian species. The mechanisms by which such an evolutionary remodeling has occurred is not well understood. To begin exploring possible mechanisms, we took advantage of a transgenic mouse model in which t... | ['Analysis of Variance', 'Animals', 'Body Weights and Measures', 'Cell Count', 'Insulin-Like Growth Factor Binding Protein 1', 'Insulin-Like Growth Factor I', 'Male', 'Mice', 'Mice, Transgenic', 'Neurons', 'Somatosensory Cortex', 'Synapses'] | 15,205,542 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D12.776.157.420.250'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cloning and characterization of a new polyketide synthase gene cluster in Streptomyces aureofaciens CCM 3239. | We cloned a new polyketide gene cluster, aur2, in Streptomyces aureofaciens CCM3239. Sequence analysis of the 9531-bp DNA fragment revealed 10 open reading frames, majority of which showed high similarity to the previously characterized type II polyketide synthase (PKS) genes. An unusual feature of the aur2 cluster is ... | ['Base Sequence', 'Blotting, Southern', 'Cloning, Molecular', 'Electrophoresis, Agar Gel', 'Gene Components', 'Molecular Sequence Data', 'Multigene Family', 'Physical Chromosome Mapping', 'Polyketide Synthases', 'Sequence Analysis, DNA', 'Streptomyces aureofaciens'] | 15,497,441 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['E05.196.401.153', 'E05.301.300.100'], ['G05.360.340.024.340.137'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['E05.393.183.620'], ['D08.811.464.257.275', 'D08.811.600.715'], ['E0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Making the diagnosis of fungal infection: when to start treatment. | Fungal infections continue to cause major complications in cancer patients. With the increasing use of aggressive chemotherapy and stem cell transplantation causing profound, prolonged depressed immunity, the risk of invasive mycoses has increased. The prognosis of these infections is poor unless they are diagnosed and... | ['Antibodies, Fungal', 'Antifungal Agents', 'Antigens, Fungal', 'DNA, Fungal', 'Humans', 'Immunologic Tests', 'Mycoses', 'Neoplasms', 'Neutropenia', 'Polymerase Chain Reaction', 'Time Factors'] | 11,091,056 | [['D12.776.124.486.485.114.179', 'D12.776.124.790.651.114.179', 'D12.776.377.715.548.114.179'], ['D27.505.954.122.136'], ['D23.050.202'], ['D13.444.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812', 'E05.200.812', 'E05.478.594'], ['C01.150.703'], ['C04'], ['C15.378.553.546.184.564'], ['E05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunoglobulin (Gm) allotypes in a sample of Canadian Ashkenazic Jews. | Gm typing on the serum specimens of 507 Ashkenazic Jews (pre-dominantly of Polish-Russian ancestry) from Toronto, Canada has established the presence of haplotypes Gm3;5, Gm1;21, Gm1,2;21, and Gm1,17;5, and the absence of haplotypes Gm1;13,15,16, Gm1;5,6, and Gm1;5,6,24 which have been found in other Jewish peoples. It... | ['Canada', 'Humans', 'Immunoglobulins', 'Isoantigens', 'Jews', 'Poland', 'Russia (Pre-1917)'] | 637,117 | [['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['D23.050.705'], ['M01.686.754.600'], ['Z01.542.248.679'], ['Z01.586.800']] | ['Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Simulated physiological stretch-induced proliferation of human bladder smooth muscle cells is regulated by MMPs. | Mechanical stimulation is an essential factor for organisms to develop normally. In bladder development matrix metalloproteinases (MMPs) play an important role through structure remodeling and regulating the cell proliferation. In this study, we investigated the simulated physiological stretch induced proliferation of ... | ['Cell Proliferation', 'Cells, Cultured', 'Collagenases', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Myocytes, Smooth Muscle', 'Phenylalanine', 'Protease Inhibitors', 'Thiophenes', 'Tissue Inhibitor of Metalloproteinase-1', 'Tissue Inhibitor of Metalloproteinase-2', 'Up-Regulation', 'Urinary Bladder'] | 25,263,962 | [['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D08.811.277.656.300.480.205', 'D08.811.277.656.675.374.205'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.620.520'], ['D12.125.072.050.685', 'D12.125.142.666'], ['D27.505.519.389.745'], ['D02.886.778', 'D03.383.903'], ['D12.776.645.875.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-time Imaging of an Experimental Intracranial Aneurysm in Rats. | Subarachnoid hemorrhage due to rupture of a pre-existing intracranial aneurysm has quite a poor outcome in spite of intensive medical care. Hemodynamic stress loaded on intracranial arterial walls is considered as a trigger and a regulator of formation and progression of the disease, but how intracranial arterial walls... | ['Animals', 'Disease Models, Animal', 'Intracranial Aneurysm', 'Microscopy, Confocal', 'Rats', 'Rats, Wistar', 'Vasodilation'] | 30,555,120 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['E01.370.350.515.395', 'E05.595.395'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G09.330.380.928']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of 5-methyltetrahydrofolate in human blood, serum and urine by on-line coupling of capillary isotachophoresis and zone electrophoresis. | The predominant circulating folate coenzyme in plasma/serum, 5-methyltetrahydrofolate (5-MTHF) was determined in human blood, serum and urine using a method based on the hyphenation of capillary ITP and zone electrophoresis. Measurements were done with a commercially available instrument for capillary isotachophoresis ... | ['Drug Stability', 'Electrophoresis, Capillary', 'Female', 'Humans', 'Isotachophoresis', 'Sensitivity and Specificity', 'Spectrophotometry, Ultraviolet', 'Tetrahydrofolates'] | 20,879,041 | [['E05.916.330'], ['E05.196.401.190', 'E05.301.300.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.401.831', 'E05.301.300.831'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['E05.196.712.726.802', 'E05.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Repetitive high-pressure recruitment maneuvers required to maximally recruit lung in a sheep model of acute respiratory distress syndrome. | OBJECTIVE: To compare the effects of two different recruitment maneuvers repeated multiple times on gas exchange lung injury, hemodynamic, and lung mechanics.DESIGN: Randomized prospective comparison.SETTINGS: Animal research laboratory.SUBJECT: Nineteen fasted Hampshire sheep.INTERVENTIONS: In 15 27-kg sheep with sali... | ['Analysis of Variance', 'Animals', 'Hemodynamics', 'Positive-Pressure Respiration', 'Pulmonary Gas Exchange', 'Respiratory Distress Syndrome', 'Sheep'] | 11,505,131 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G09.330.380'], ['E02.041.625.790', 'E02.880.820.790'], ['E01.370.386.700.650', 'G03.143.775.602', 'G09.772.705.760.602'], ['C08.381.840', 'C08.618.840'], ['B01.050.150.900.649.313.500.380.791']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Non-metric multidimensional scaling and human risks of heavy metal concentrations in wild marine organisms from the Maowei Sea, the Beibu Gulf, South China Sea. | We investigated heavy metal concentrations in wild marine organisms from Maowei Sea, a significant gulf of low-latitude developing regions of the Beibu Gulf, South China Sea. Twenty species, comprising fish, cephalopods, and crustaceans were collected and analyzed for heavy metals. Heavy metal levels (mg/kg, wet weight... | ['Animals', 'Cephalopoda', 'China', 'Crustacea', 'Environmental Monitoring', 'Fishes', 'Food Contamination', 'Humans', 'Metals, Heavy', 'Oceans and Seas', 'Seafood', 'Water Pollutants, Chemical'] | 29,571,006 | [['B01.050'], ['B01.050.500.644.116'], ['Z01.252.474.164'], ['B01.050.500.131.365'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.493'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556', 'D01.552.544'], ['G01.311.... | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Chemical Strike against a Dominant-Inherited MUC1-Frameshifted Protein Associated with Progressive Kidney Disease. | In a recent paper by Dvela-Levitt et al., chemical screening using an immunofluorescent assay identified a compound that caused removal of a dominant-inherited misfolded secretory protein, mucin1-frameshifted, from an intracellular location in immortalized renal epithelial cells of a patient affected with progressive m... | ['Animals', 'Drug Evaluation, Preclinical', 'Endoplasmic Reticulum', 'Frameshifting, Ribosomal', 'Humans', 'Kidney', 'Kidney Diseases, Cystic', 'Mice', 'Mucin-1', 'Protein Folding', 'Unfolded Protein Response'] | 31,521,560 | [['B01.050'], ['E05.290.750', 'E05.337.550'], ['A11.284.430.214.190.875.248'], ['G02.111.660.871.200', 'G03.734.871.200', 'G05.308.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.403', 'C13.351.968.419.403'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.395.550.560', 'D1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of correct implant size in radial head arthroplasty to avoid overlengthening: surgical technique. | BACKGROUND: Insertion of a radial head implant that results in radial overlengthening has been associated with altered elbow kinematics, increased radiocapitellar joint forces, capitellar erosions, early-onset arthritis, and loss of elbow flexion. The purpose of this study was to identify clinical and radiographic feat... | ['Arthroplasty, Replacement', 'Elbow Joint', 'Follow-Up Studies', 'Fractures, Comminuted', 'Humans', 'Intra-Articular Fractures', 'Joint Prosthesis', 'Postoperative Complications', 'Prosthesis Design', 'Radius Fractures', 'Range of Motion, Articular', 'Risk Assessment', 'Treatment Outcome'] | 20,844,180 | [['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['A02.835.583.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.404.505'], ['E07.695.400'], ['C23.550.767'], ['E05.320.550', 'E07.695.680'], ['C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Water pipe smoking and health-related quality of life: a population-based study. | BACKGROUND: Water pipe smoking is increasing in Eastern Mediterranean Region. The objective of this study was to investigate any relationship between water pipe smoking and health-related quality of life in the general population of Bandar Abbas, Iran.METHODS: Using a multistage sampling method, a random sample of 1675... | ['Adolescent', 'Adult', 'Age Distribution', 'Cross-Sectional Studies', 'Female', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Population Surveillance', 'Prevalence', 'Quality of Life', 'Retrospective Studies', 'Risk Factors', 'Sex Distribution', 'Smoking', 'Young Adult'] | 19,400,599 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['M01.060.116.630'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Humanities [K]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Isolation and purification of bovine retina S-antigen]. | Fresh bovine retinas were precipitated by ammonium sulfate, and further purified by the Sephadex G-200 column and the hydroxyapatite column. Through the SDS polyacrylamide gel electrophoresis and the isoelectric focusing gel electrophoresis, a single band of protein with molecular weight of 50,000 daltons, isoelectric ... | ['Animals', 'Antigens', 'Arrestin', 'Autoimmune Diseases', 'Cattle', 'Disease Models, Animal', 'Eye Proteins', 'Guinea Pigs', 'Molecular Weight', 'Retina', 'Uveitis'] | 3,816,363 | [['B01.050'], ['D23.050'], ['D12.644.360.024.098.050', 'D12.776.157.057.005.050', 'D12.776.306.090.050', 'D12.776.476.024.104.050', 'D12.776.543.090.050', 'D23.050.301.280'], ['C20.111'], ['B01.050.150.900.649.313.500.380.271'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.306'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between dietary inflammatory index and prostate cancer among Italian men. | Previous studies have shown that various dietary components may be implicated in the aetiology of prostate cancer, although the results remain equivocal. The possible relationship of inflammation derived from dietary exposures with prostate cancer risk has not been investigated. We examined the ability of a newly devel... | ['Aged', 'Carcinoma', 'Case-Control Studies', 'Diet', 'Hospitals, General', 'Hospitals, Teaching', 'Humans', 'Immunologic Surveillance', 'Incidence', 'Italy', 'Male', 'Middle Aged', 'Nutrition Policy', 'Patient Compliance', 'Prostate', 'Prostatic Neoplasms', 'Prostatitis', 'Risk Factors', 'Self Report'] | 25,400,225 | [['M01.060.116.100'], ['C04.557.470.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.203.650.240'], ['N02.278.421.389'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.400.412', 'G12.525'], ['E05.318.308.985.525.375', 'N0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Dopamine receptor subtype density as a function of age in Aplysia californica. | The age-associated changes in dopamine subtype receptors were examined in Aplysia californica. The density of the subtype receptors D1, D2, D3 and D4 was examined in the ganglia from 4.5-, 6-, 8-, 9- and 12-month animals. Receptor analysis was performed by examining the binding of radiolabeled ligands to the individual... | ['Age Factors', 'Aging', 'Analysis of Variance', 'Animals', 'Aplysia', 'Ganglia', 'Protein Binding', 'Radioligand Assay', 'Receptors, Dopamine', 'Time Factors'] | 11,691,623 | [['N05.715.350.075', 'N06.850.490.250'], ['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.500.644.400.060'], ['A08.340'], ['G02.111.679', 'G03.808'], ['E01.370.225.985', 'E01.370.374.650', 'E01.370.384.720', 'E05.200.985'], ['D12.776.543.750.670.300.400', 'D12.7... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Microembolization and myonecrosis during elective percutaneous coronary interventions in diabetic patients: an intracoronary Doppler ultrasound study with 2-year clinical follow-up. | Elevation of cardiac troponin I (cTnI) is a well-known complication after percutaneous coronary interventions (PCI). The aims of this study were to quantify the extent of coronary microembolization during elective PCI, to identify predisposing anatomical and procedural factors, and to evaluate its impact on long-term o... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Artery Disease', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Elective Surgical Procedures', 'Embolism', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardium', 'Necrosis', 'Prospective Studies', 'Troponin I', 'Ultrasonography, Doppler... | 22,850,870 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C18.452.394.750.149', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biochemical and cytogenetical characterization of Chinese hamster ovary X-ray-sensitive mutant cells xrs 5 and xrs 6. VI. The correlation between UV-induced DNA lesions and chromosomal aberrations, and their modulations with inhibitors of DNA repair synthesis. | The role of UV-induced DNA lesions and their repair in the formation of chromosomal aberrations in the xrs mutant cell lines xrs 5 and xrs 6 and their wild-type counterpart, CHO-K1 cells, were studied. The extent of induction of DNA single-strand breaks (SSBs) and DNA double-strand breaks (DSBs) due to UV irradiation i... | ['Animals', 'Cell Line', 'Chromosome Aberrations', 'Cricetinae', 'Cricetulus', 'Cytarabine', 'DNA', 'DNA Damage', 'DNA Repair', 'DNA Replication', 'DNA, Single-Stranded', 'Hydroxyurea', 'Mutation', 'Radiation Tolerance', 'Ultraviolet Rays', 'X-Rays'] | 2,308,589 | [['B01.050'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['D13.444.308'], ['G05.200'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Interlaboratory comparison of antisera and immunoassays for benzo[a]pyrene-diol-epoxide-I-modified DNA. | An interlaboratory comparison of immunoassays using antisera elicited against benzo[a]pyrene-diol-epoxide-modified DNA (BPDE-I-DNA) was carried out resulting in standardization of antisera, competitors and assay conditions. The assays used included competitive enzyme-linked immunosorbent assays (ELISA) with color and f... | ['7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide', 'Animals', 'Antibody Specificity', 'DNA', 'DNA Adducts', 'DNA Damage', 'Dihydroxydihydrobenzopyrenes', 'Immunoassay', 'Mice', 'Skin'] | 3,133,129 | [['D02.455.426.559.847.799.306.400.350', 'D04.615.799.306.400.350'], ['B01.050'], ['G12.100'], ['D13.444.308'], ['D13.444.308.135', 'G05.200.104'], ['G05.200'], ['D02.455.426.559.847.799.306.400', 'D04.615.799.306.400'], ['E05.478.566', 'E05.601.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['A17.815']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nature and incidence of bubbles in the spinal cord of decompressed goats. | The nature of so-called autochthonous bubbles was investigated. Their presence in compressed/decompressed goats was compared with that in animals killed before decompression and in controls. Ten goats (group 1) were subjected to compression/decompression in air. Clinical signs of spinal decompression sickness usually o... | ['Animals', 'Connective Tissue', 'Decompression', 'Decompression Sickness', 'Dilatation, Pathologic', 'Female', 'Goats', 'Male', 'Paralysis', 'Spinal Cord', 'Spinal Cord Diseases', 'Vascular Diseases'] | 9,308,143 | [['B01.050'], ['A10.165'], ['E02.278', 'G01.374.715.250'], ['C26.120.248'], ['C23.300.325'], ['B01.050.150.900.649.313.500.380.513'], ['C10.597.622', 'C23.888.592.636'], ['A08.186.854'], ['C10.228.854'], ['C14.907']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative studies of sulphate conjugation by isolated rat liver cells using [35S]sulphate. | We have developed a simple, rapid and sensitive method for the study of sulphate conjugation in isolated liver cells based on the incorporation of 35S from [35S]sulphate. Excess [35S]sulphate is removed by a barium precipitation procedure, leaving [35S]sulphate conjugates in solution. We have used this method to examin... | ['Acetaminophen', 'Animals', 'Barium', 'Cells, Cultured', 'Chromatography, High Pressure Liquid', 'Glucuronates', 'Kinetics', 'Liver', 'Male', 'Naphthols', 'Nitrophenols', 'Rats', 'Sulfates', 'Sulfur Radioisotopes'] | 2,069,597 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['B01.050'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['A11.251'], ['E05.196.181.400.300'], ['D02.241.081.844.915.162', 'D02.241.152.811.162', 'D02.241.511.902.915.162', 'D09.811.922.162'], ['G01.374.661', 'G02.111.490'], ['A03.62... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adrenocortical pregnenolone-binding protein: identification and antibody development. | Pregnenolone-binding activity isolated from the cytosol of the guinea pig adrenal cortex appears to correspond to a Mr 34,000 protein when examined by SDS-polyacrylamide gel electrophoresis during different stages of purification. To verify this finding the Mr 34,000 protein band was eluted from the SDS gel and used to... | ['Adrenal Cortex', 'Animals', 'Antibodies', 'Antigens', 'Carrier Proteins', 'Chromatography', 'Cytosol', 'Electrophoresis, Polyacrylamide Gel', 'Guinea Pigs', 'Immunoassay', 'Immunoglobulin G', 'Male', 'Molecular Weight', 'Pregnenolone'] | 3,337,724 | [['A06.300.071.140'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.050'], ['D12.776.157'], ['E05.196.181'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.992.550'], ['E05.4... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intracellular pH modulates quinary structure. | NMR spectroscopy can provide information about proteins in living cells. pH is an important characteristic of the intracellular environment because it modulates key protein properties such as net charge and stability. Here, we show that pH modulates quinary interactions, the weak, ubiquitous interactions between protei... | ['Amides', 'Escherichia coli Proteins', 'Hydrogen-Ion Concentration', 'Intracellular Space', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Stability', 'Protons'] | 26,257,390 | [['D02.065'], ['D12.776.097.275'], ['G02.300'], ['A10.082.750', 'A11.284.430'], ['E05.196.867.519.550'], ['G02.111.700'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isotropic Versus Bipolar Functionalized Biomimetic Artificial Basement Membranes and Their Evaluation in Long-Term Human Cell Co-Culture. | In addition to dividing tissues into compartments, basement membranes are crucial as cell substrates and to regulate cellular behavior. The development of artificial basement membranes is indispensable for the ultimate formation of functional engineered tissues; however, pose a challenge due to their complex structure.... | ['Animals', 'Basement Membrane', 'Biomimetic Materials', 'Cattle', 'Cell Line', 'Coculture Techniques', 'Fibroblasts', 'Humans', 'Keratinocytes', 'Male'] | 27,283,510 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['J01.637.087'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['E05.481.500.374'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A11.436.397']] | ['Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Efficient real-time confocal microscopy with white light sources. | The main advantage of confocal microscopes over their conventional counterparts arises from their ability to optically 'section' nearly transparent materials; the thin image slices thus obtained can be used to reconstruct three-dimensional images, a capability which is particularly useful for the study of biological sp... | ['Animals', 'Light', 'Mice', 'Microscopy, Confocal', 'Osteoclasts', 'Thalamus', 'Whales'] | 8,893,003 | [['B01.050'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.395', 'E05.595.395'], ['A11.329.372.700', 'A11.627.482.700'], ['A08.186.211.200.317.826'], ['B01.050.150.900.649.313.875.865']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ex vivo lung perfusion and extracorporeal life support in lung transplantation. | Normothermic ex vivo lung perfusion and extracorporeal life support have re-invigorated lung transplantation. | ['Donor Selection', 'Extracorporeal Membrane Oxygenation', 'Humans', 'Lung', 'Lung Transplantation', 'Perfusion'] | 22,172,352 | [['E04.936.537.500', 'N02.421.911.600'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E04.928.600.495', 'E04.936.450.495'], ['E05.680']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Drought and Recovery: Independently Regulated Processes Highlighting the Importance of Protein Turnover Dynamics and Translational Regulation in Medicago truncatula. | Climate change in conjunction with population growth necessitates a systems biology approach to characterize plant drought acclimation as well as a more thorough understanding of the molecular mechanisms of stress recovery. Plants are exposed to a continuously changing environment. Extremes such as several weeks of dro... | ['Chromatography, Liquid', 'Droughts', 'Gene Expression Regulation, Plant', 'Gene Regulatory Networks', 'Medicago truncatula', 'Metabolomics', 'Plant Proteins', 'Proteomics', 'Stress, Physiological', 'Systems Biology', 'Tandem Mass Spectrometry'] | 27,001,437 | [['E05.196.181.400'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['G05.308.375'], ['G05.360.080.689.360'], ['B01.650.940.800.575.912.250.401.590.750'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['D12.776.765'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Correlation between inducible nitric oxide synthase and p53 expression for DMBA-induced hamster buccal-pouch carcinomas. | UNLABELLED: Three isoforms of nitric oxide synthase (NOS) have been identified previously--endothelial NOS, neuronal NOS, and inducible NOS (iNOS). It has been reported previously that there may be a negative feedback loop existing between nitric oxide (NO) production and wild-type p53 tumor-suppressor gene, but the re... | ['9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'Carcinogens', 'Carcinoma, Squamous Cell', 'Cheek', 'Cricetinae', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Neoplastic', 'Genes, p53', 'Immunohistochemistry', 'Male', 'Mesocricetus', 'Mouth Neoplasms', 'Nitric Oxide Synthase', 'Nitric Oxide S... | 14,628,889 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['D27.888.569.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A01.456.505.173', 'A14.194'], ['B01.050.150.900.649.313.992.635.075.250'], ['G05.308.320'], ['G05.308.370'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Risk factors for vitamin D deficiency among HIV-infected and uninfected injection drug users. | INTRODUCTION: Vitamin D deficiency is highly prevalent and is associated with bone disease, cardiovascular disease, metabolic syndrome and malignancy. Injection drug users (IDUs), with or without HIV infection, are at risk for these conditions; however, limited data on vitamin D deficiency exist in this population. We ... | ['Adult', 'Cross-Sectional Studies', 'Drug Users', 'Female', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Odds Ratio', 'Risk Factors', 'Vitamin D Deficiency'] | 24,756,000 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.169'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.60... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polymerase chain reaction for detection of herpesvirus simiae (B virus) in clinical specimens. | A polymerase chain reaction (PCR) was designed which is specific to Macaca fascicularis (cynomolgus monkey) isolates of B virus. The PCR primers produced the expected 188 basepair product from the Cyno 2 strain and seven other cynomolgus monkey isolates of B virus. Oligomer hybridization with a 31-mer oligonucleotide w... | ['Animals', 'Base Sequence', 'Brain', 'DNA, Single-Stranded', 'DNA, Viral', 'Female', 'Ganglia, Spinal', 'Herpesviridae Infections', 'Herpesvirus 1, Cercopithecine', 'Macaca fascicularis', 'Molecular Sequence Data', 'Mouth', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Trigeminal Ganglion', 'Vagina', 'V... | 8,392,323 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D13.444.308.568'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['C01.925.256.466'], ['B04.280.382.100.750.350'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Problematic eating behaviors and attitudes predict long-term incident metabolic syndrome and diabetes: The Coronary Artery Risk Development in Young Adults Study. | BACKGROUND: Problematic relationship to eating and food (PREF) captures a broad range of unhealthy eating behaviors. We previously reported that higher BMI is associated with PREF and graded by the number of PREF endorsed. In this study, we prospectively examined the association between PREF and metabolic syndrome and ... | ['Adult', 'Coronary Vessels', 'Diabetes Mellitus', 'Feeding Behavior', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Metabolic Syndrome', 'Risk Factors'] | 30,636,022 | [['M01.060.116'], ['A07.015.114.269', 'A07.015.908.194'], ['C18.452.394.750', 'C19.246'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C18.452.394.968.500.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytoplasmic and Nuclear Localizations Are Important for the Hypersensitive Response Conferred by Maize Autoactive Rp1-D21 Protein. | Disease resistance (R) genes have been isolated from many plant species. Most encode nucleotide binding leucine-rich repeat (NLR) proteins that trigger a rapid localized programmed cell death called the hypersensitive response (HR) upon pathogen recognition. Despite their structural similarities, different NLR are dist... | ['Cell Nucleus', 'Cytoplasm', 'Gene Expression Regulation, Plant', 'Plant Proteins', 'Protein Transport', 'Zea mays'] | 26,039,083 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['G05.308.375'], ['D12.776.765'], ['G03.143.700'], ['B01.650.940.800.575.912.250.822.966']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical visualization of pro-inflammatory cytokines and enzymes in ovarian tumors. | Epithelial ovarian cancer represents one of the most deadly gynaecological neoplasms in developed countries and is a highly heterogeneous disease. Epidemiological studies show that anti-inflammatory drugs reduce the incidence and mortality of several types of cancer, indicating the potential role of pro-inflammatory fa... | ['Adult', 'Carcinoma', 'Case-Control Studies', 'Cyclooxygenase 2', 'Cytokines', 'Female', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'NF-kappa B', 'Nitric Oxide Synthase Type II', 'Ovarian Neoplasms'] | 25,007,180 | [['M01.060.116'], ['C04.557.470.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D08.811.600.720.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of several fluorescent detector molecules for protein microarray use. | The utility of several streptavidin-linked fluorescent detector molecules was evaluated on two protein microarray platforms. Tested detector molecules included: Alexa Fluor 546; R-phycoerythrin (RPE), orange fluospheres; Cy3-containing liposomes (Large Unilamellar Vesicles, LUV) labelled with Cy3; and an RPE-antibody c... | ['Animals', 'Biotin', 'Carbocyanines', 'Fluorescent Dyes', 'Immunoglobulin G', 'Liposomes', 'Mice', 'Phycoerythrin', 'Protein Array Analysis', 'Rabbits', 'Sensitivity and Specificity'] | 12,536,376 | [['B01.050'], ['D03.383.129.308.080', 'D08.211.096'], ['D02.455.326.397.300'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['B0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Abnormal drug metabolism in chronic pancreatitis. Treatment with antioxidants. | Functional and morphological changes in hepatocytes, indicating induction of the drug metabolizing enzymes and free radical-mediated damage, were found in 4 patients with idiopathic chronic pancreatitis. The possibility that reflux of abnormal bile (rich in lipid peroxidation and other products generated through hepati... | ['Adolescent', 'Adult', 'Antioxidants', 'Biopsy', 'Chronic Disease', 'Combined Modality Therapy', 'Drug Therapy, Combination', 'Humans', 'Liver', 'Male', 'Methionine', 'Middle Aged', 'Pancreas', 'Pancreatectomy', 'Pancreatitis', 'Selenium', 'Tablets'] | 2,298,375 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C23.550.291.500'], ['E02.186'], ['E02.319.310'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
beta-Adrenoreceptor-blocking agents and the blood-brain barrier. | 1. Sixteen neurosurgical patients received (oral) beta-adrenoreceptor-blocking agents (beta-receptor blockers) for 3-22 days. 2. Lipophilic beta-receptor blockers (propranolol) and metoprolol appeared in cerebrospinal fluid at concentrations similar to the free drug plasma concentration. 3. Cerebrospinal fluid concentr... | ['Atenolol', 'Blood-Brain Barrier', 'Brain', 'Humans', 'Kinetics', 'Metoprolol', 'Propanolamines', 'Propranolol'] | 7,449,299 | [['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D02.033.100.624.698.573', 'D02.033.755.624.698.573', 'D02.092.063.624.698.573'], ['D02.033.100.624', 'D0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of external helmet accessories on biomechanical measures of head injury risk: An ATD study using the HYBRIDIII headform. | Competitive cycling is a popular activity in North America for which injuries to the head account for the majority of hospitalizations and fatalities. In cycling, use of helmet accessories (e.g. cameras) has become widespread. As a consequence, standards organizations and the popular media are discussing the role these... | ['Acceleration', 'Bicycling', 'Biomechanical Phenomena', 'Brain Concussion', 'Craniocerebral Trauma', 'Head', 'Head Protective Devices', 'Humans', 'Male', 'Photography', 'Risk'] | 26,477,409 | [['G01.482.107'], ['I03.450.642.845.140'], ['G01.154.090', 'G01.374.089'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['C10.900.300', 'C26.915.300'], ['A01.456'], ['E07.700.380', 'J01.637.708.560.750'], ['B01.050.15... | ['Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Novel technique for implantation of a cardioverter defibrillator in children. | An 8-year-old boy with hypertrophic nonobstructive cardiomyopathy with ventricular fibrillation underwent implantation of an implantable cardioverter defibrillator. The lead was inserted through a pursestring suture in the right atrial appendage, and the tip of coil was placed in the right ventricular apex under fluoro... | ['Cardiomyopathy, Hypertrophic', 'Child', 'Defibrillators, Implantable', 'Humans', 'Male', 'Ventricular Fibrillation'] | 24,882,336 | [['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['M01.060.406'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.067.922', 'C23.550.073.922']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells. | Extracellular vesicles (ECVs) facilitate intercellular communication along the nephron, with the potential to change the function of the recipient cell. However, it is not known whether this is a regulated process analogous to other signaling systems. We investigated the potential hormonal regulation of ECV transfer an... | ['Adolescent', 'Animals', 'Deamino Arginine Vasopressin', 'Extracellular Vesicles', 'Humans', 'Kidney Tubules, Collecting', 'Male', 'Mice', 'Rats', 'Vasopressins'] | 27,020,854 | [['M01.060.057'], ['B01.050'], ['D06.472.699.631.692.781.100.250', 'D12.644.400.900.100.250', 'D12.644.456.925.100.250', 'D12.644.548.691.692.781.100.250', 'D12.776.631.650.937.100.250'], ['A11.284.295.588'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.736.560.510'], ['B01.050.150.900.649.313.992.635... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic. | Using a modified liver homogenate model to assay for the inhibition of cholesterol biosynthesis, different garlic and wild garlic extracts as well as pure compounds isolated from them were investigated for their influence on cholesterol synthesis. Chloroform and acetone/chloroform extracts of garlic and wild garlic inh... | ['Animals', 'Cholesterol', 'Garlic', 'In Vitro Techniques', 'Liver', 'Male', 'Plant Extracts', 'Plants, Medicinal', 'Rats', 'Rats, Inbred Strains'] | 1,632,861 | [['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.650.940.800.575.912.250.618.100.050.060.300'], ['E05.481'], ['A03.620'], ['D20.215.784.500', 'D26.667'], ['B01.650.560'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of histiocytosis X complicated by recurrent spontaneous pneumothorax]. | A rare case of the generalized of histiocytosis X is described. Due to pulmonary involvement the disease was complicated by three episodes of spontaneous pneumothorax. | ['Combined Modality Therapy', 'Histiocytosis, Langerhans-Cell', 'Humans', 'Infant', 'Male', 'Pneumothorax', 'Recurrence'] | 1,462,573 | [['E02.186'], ['C08.381.483.375', 'C15.604.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08.528.778'], ['C23.550.291.937']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Photofrin-mediated photodynamic therapy of chemically-induced premalignant lesions and squamous cell carcinoma of the palatal mucosa in rats. | Photodynamic therapy (PDT), an experimental cancer therapy, was studied in an animal model of chemically-induced epithelial dysplasia and squamous cell carcinoma. PDT was performed 24 hours after i.v. injection of 2.5 mg/kg bw Photofrin, and using 100 J/cm2 incident light at two activation wavelengths (514.5 nm or 625 ... | ['4-Nitroquinoline-1-oxide', 'Animals', 'Antineoplastic Agents', 'Carcinogens', 'Carcinoma, Squamous Cell', 'Disease Models, Animal', 'Edema', 'Erythema', 'Hematoporphyrin Derivative', 'Injections, Intravenous', 'Longitudinal Studies', 'Male', 'Mouth Diseases', 'Mouth Mucosa', 'Necrosis', 'Oral Hemorrhage', 'Palatal Ne... | 9,180,236 | [['D02.640.820.600', 'D03.633.100.810.470.450', 'D03.661.243.500'], ['B01.050'], ['D27.505.954.248'], ['D27.888.569.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.888.277'], ['C17.800.229', 'C23.888.885.328'], ['D03.383.129.578.840.500.462.400', 'D03.633.400.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhaled corticosteroids and growth of airway function in asthmatic children. | Airway inflammation and remodelling play an important role in the pathophysiology of asthma. Remodelling may affect childhood lung function, and this process may be reversed by anti-inflammatory treatment. The current study assessed longitudinally whether asthma affects growth of airway function relative to airspaces, ... | ['Administration, Inhalation', 'Adolescent', 'Adrenal Cortex Hormones', 'Albuterol', 'Analysis of Variance', 'Asthma', 'Bronchodilator Agents', 'Budesonide', 'Child', 'Double-Blind Method', 'Female', 'Humans', 'Longitudinal Studies', 'Lung', 'Male', 'Respiratory Function Tests', 'Treatment Outcome'] | 15,218,999 | [['E02.319.267.050'], ['M01.060.057'], ['D06.472.040'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Share your story with us: When mentorship mattered. | Send us up to 1,000 words on how being a mentor or mentee shaped your practice. | ['Humans', 'Mentors', 'Narration'] | 31,764,544 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.395'], ['E05.318.308.502', 'F01.145.209.459', 'L01.399.250.660', 'N05.715.360.300.480', 'N06.850.520.308.502']] | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Congenital multifocal increase of Purkinje fibres in a calf with cardiac conduction delay. | A female 4-month-old Holstein-Friesian calf was presented in heart failure. Microscopical examination of samples of the cardiac wall taken at necropsy examination revealed numerous aggregates of Purkinje fibres, particularly in the perivascular areas. Some Purkinje fibres were stained strongly with phosphotungstic acid... | ['Animals', 'Arrhythmias, Cardiac', 'Brugada Syndrome', 'Cardiac Conduction System Disease', 'Cattle', 'Cattle Diseases', 'Female', 'Heart Conduction System', 'Purkinje Fibers'] | 25,084,712 | [['B01.050'], ['C14.280.067', 'C23.550.073'], ['C14.280.067.322', 'C14.280.123.250', 'C16.320.100'], ['C14.280.123'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A07.541.409'], ['A07.541.409.683']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beta-endorphin. Biological activity of synthetic analogs with analgesia inhibiting property in rat vas deferens and guinea pig ileum assays. | Three synthetic analogs of human beta-endorphin (beta h-EP) (I, [Gln8, Gly31]-beta h-EP-Gly-Gly-NH2; II, [Arg9,12,24,28,29]-beta h-EP and III, [Cys11,26, Phe27, Gly31]-beta h-EP), which have been shown to possess potent inhibiting activity to beta h-EP-induced analgesia, were assayed in rat vas deferens and guinea pig ... | ['Analgesia', 'Animals', 'Electric Stimulation', 'Endorphins', 'Guinea Pigs', 'Ileum', 'Male', 'Muscle Contraction', 'Rats', 'Vas Deferens', 'beta-Endorphin'] | 3,158,621 | [['E03.091'], ['B01.050'], ['E05.723.402'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['B01.050.150.900.649.313.992.550'], ['A03.556.124.684.249', 'A03.556.249.124'], ['G11.427.494'], ['B01.050.150.900.649.313.992.635.505.700'], ['A05.360.444.930'], ['D06.472.699.327.935.239', 'D06.472.699.631.525.600.239', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The development and validation of the impact of multiple sclerosis scale and the symptoms of multiple sclerosis scale. | OBJECTIVE: To develop and validate the Impact of Multiple Sclerosis Scale (IMSS) and the Symptoms of Multiple Sclerosis Scale (SMSS) using the Extended Disability Status Scale (EDSS) for construct validity.DESIGN: Panel design involving test-retest over 4 months.SETTING: A mailed survey.PARTICIPANTS: Volunteers with a ... | ['Adult', 'Data Interpretation, Statistical', 'Disability Evaluation', 'Female', 'Humans', 'Male', 'Multiple Sclerosis', 'Psychometrics', 'Reproducibility of Results', 'Sickness Impact Profile'] | 16,731,220 | [['M01.060.116'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Methods of expressing the strength of expert proof of paternity determination]. | Non-exclusion from paternity of alleged man can be quantified by pre-test and post-test parameters. Author advocates the view that expression of the power of forensic expert evidence by likelihood ratio, which compares probability of data under two hypotheses, is the best approach from both the point of forensic mathem... | ['Bayes Theorem', 'Forensic Medicine', 'Humans', 'Likelihood Functions', 'Male', 'Microsatellite Repeats', 'Paternity', 'Probability'] | 12,238,022 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Biophysical and electrophysiological studies of hexanedione neurotoxicity. | This study examined the significance of nerve microviscosity changes which occur in 2,5-hexanedione (2,5-HD) neurotoxicity. To establish a correlation between microviscosity changes and neuronal damage, a standard axonal neuropathy (nerve section) was employed. Electrophysiological studies of the sciatic-tibial nerve o... | ['Animals', 'Electromyography', 'Erythrocyte Membrane', 'Erythrocytes', 'Fluorescence', 'Hexanones', 'Ketones', 'Male', 'Myelin Sheath', 'Nerve Degeneration', 'Nervous System', 'Neural Conduction', 'Rats', 'Rats, Inbred Strains', 'Viscosity'] | 7,199,690 | [['B01.050'], ['E01.370.405.255', 'E01.370.530.255'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D02.522.520'], ['D02.522'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in Chinese valve replacement patients. | BACKGROUND: Individuals with implanted mechanical valve prostheses require lifelong anticoagulation therapy with warfarin. The narrow therapeutic index of warfarin makes it difficult to dose and maintain proper anticoagulation. A number of single nucleotide polymorphisms (SNPs) affecting vitamin K or warfarin metabolis... | ['Adult', 'Anticoagulants', 'China', 'Cohort Studies', 'Cytochrome P-450 Enzyme System', 'Cytochrome P450 Family 4', 'Female', 'Heart Valve Prosthesis', 'Humans', 'International Normalized Ratio', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Thrombosis', 'Warfarin'] | 23,013,706 | [['M01.060.116'], ['D27.505.954.502.119'], ['Z01.252.474.164'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D08.244.453.870', 'D08.811.682.690.708.170.496', 'D12.776.422.220.453.870'], ['E07.695.310'], ['B01.050.150.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Patient satisfaction with HIV/AIDS care at private clinics in Dar es Salaam, Tanzania. | Health system responsiveness (HSR) measures quality of care from the patient's perspective, an important component of ensuring adherence to medication and care among HIV patients. We examined HSR in private clinics serving HIV patients in Dar es Salaam, Tanzania. We surveyed 640 patients, 18 or older receiving care at ... | ['Adult', 'Aged', 'Demography', 'Female', 'HIV Infections', 'Health Services Accessibility', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Private Sector', 'Quality of Health Care', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Tanzania'] | 24,499,337 | [['M01.060.116'], ['M01.060.116.100'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.10... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The genetic diversity and applicability assessment of autosomal STRs among Chinese populations by a novel Fixation Index and Nei's index. | The population-specific FST in STR loci of Chinese populations has not been focused on. Here, we genotyped 19 STRs in 530 unrelated healthy individuals of Xuzhou Han population, and collected data of 30,308 samples from 32 Hans and 50 minorities nationwide. The population-specific âi and locus-specific âil were calcula... | ['Asian Continental Ancestry Group', 'Forensic Genetics', 'Genetic Variation', 'Genetics, Population', 'Genotype', 'Humans', 'Microsatellite Repeats', 'Minority Groups', 'Polymorphism, Genetic'] | 29,324,252 | [['M01.686.508.200'], ['H02.403.330.149', 'I01.198.780.937.441'], ['G05.365'], ['H01.158.273.343.335'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['I01.880.853.300'], ['G05.365.795']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Candida glabrata species complex prevalence and antifungal susceptibility testing in a culture collection: First description of Candida nivariensis in Argentina. | The presence of the cryptic species belonging to the Candida glabrata complex has not been studied in Argentina. We analyzed a collection of 117 clinical isolates of C. glabrata complex belonging to a National Culture Collection of Instituto Nacional de Microbiolog?a "Dr. Carlos G. Malbr?n" from Argentina (40 isolates ... | ['Antifungal Agents', 'Argentina', 'Candida glabrata', 'Candidiasis', 'Culture Media', 'Humans', 'Microbiological Techniques', 'Molecular Diagnostic Techniques', 'Polymerase Chain Reaction', 'Prevalence', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 27,681,573 | [['D27.505.954.122.136'], ['Z01.107.757.077'], ['B01.300.107.795.095.400', 'B01.300.381.147.400', 'B01.300.930.176.400'], ['C01.150.703.160'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875', 'E05.200.875'], ['E01.370.225.880', 'E05.200.880', 'E05.393.520'], ['E05.393... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Variation of amide proton transfer signal intensity and apparent diffusion coefficient values among phases of the menstrual cycle in the normal uterus: A preliminary study. | PURPOSE: To explore changes in the amide proton transfer (APT) signal intensity (SI) among different phases of the menstrual cycle in healthy young women and to determine whether the APT SI correlates with the apparent diffusion coefficient (ADC).MATERIALS AND METHODS: Twenty healthy women of childbearing age received ... | ['Adult', 'Algorithms', 'Amides', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Healthy Volunteers', 'Humans', 'Image Processing, Computer-Assisted', 'Menstrual Cycle', 'Myometrium', 'Protons', 'Uterus'] | 31,319,128 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['D02.065'], ['E01.370.350.825.500.150'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G08.686.605'], ['A02.633.570.500', 'A05.360.319.679.690', 'A10.690.467.500'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.36... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Evidence of the co-activation of alpha-motoneurones and static gamma-motoneurones of the sartorius medialis muscle during locomotion in the thalamic cat. | The activity in alpha and gamma efferent axon populations and in group I and group II afferent fibre populations innervating a flexor muscle, the sartorius medialis, was observed during spontaneous locomotor movements in the thalamic cat. Multi-unit discharges of each kind of fibre were obtained by electronic sorting o... | ['Animals', 'Axons', 'Cats', 'Electromyography', 'Hindlimb', 'Locomotion', 'Motor Neurons', 'Muscle Contraction', 'Muscles', 'Neurons, Afferent', 'Neurons, Efferent', 'Stereotyped Behavior', 'Thalamus'] | 2,257,904 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E01.370.405.255', 'E01.370.530.255'], ['A13.473'], ['G07.568.500', 'G11.427.410.568'], ['A08.675.655.500', 'A11.671.655.500'], ['G11.427.494'], ['A02.633', 'A10.690'], ['A08.675.650... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum. | Azithromycin has antimalarial activity and favourable pharmacokinetic properties for a prophylactic antimalarial agent. We investigated the ability of azithromycin to prevent malaria in volunteers infected with a chloroquine-resistant strain of Plasmodium falciparum. 4 volunteers received oral azithromycin 500 mg follo... | ['Administration, Oral', 'Adolescent', 'Adult', 'Azithromycin', 'Chloroquine', 'Drug Administration Schedule', 'Drug Resistance', 'Humans', 'Malaria, Falciparum', 'Pilot Projects'] | 7,910,886 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['D02.540.576.500.992.050'], ['D03.633.100.810.050.180'], ['E02.319.283'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530.650', 'C01.920.875.650'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Global costs attributed to chronic kidney disease: a systematic review. | OBJECTIVE: The aim of this study is to discuss the global costs attributed to chronic kidney disease (CKD) and its impact on healthcare systems of developing countries, such as Brazil.METHODS: This is a systematic review based on data from PubMed/Medline, using the key words "costs" and "chronic kidney disease", in Jan... | ['Cost of Illness', 'Health Expenditures', 'Humans', 'Renal Insufficiency, Chronic'] | 30,569,987 | [['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750', 'C13.351.968.419.780.750']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Gambian National Impregnated Bednet Programme: costs, consequences and net cost-effectiveness. | Clinical trials have indicated that treating mosquito nets with insecticide could be a potentially cost-effective method of preventing malaria. As malaria is one of the most common causes of death in children under five in developing countries, there has been substantial interest in whether such findings can be replica... | ['Bedding and Linens', 'Child', 'Child, Preschool', 'Communicable Disease Control', 'Cost-Benefit Analysis', 'Female', 'Gambia', 'Health Care Costs', 'Humans', 'Infant', 'Infant Mortality', 'Insect Bites and Stings', 'Insecticides', 'Malaria', 'Male'] | 9,447,642 | [['E07.325.137', 'J01.494.221'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.780.200'], ['N03.219.151.125'], ['Z01.058.290.190.300'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Increasing stroke incidence in Sweden between 1989 and 2000 among persons aged 30 to 65 years: evidence from the Swedish Hospital Discharge Register. | BACKGROUND AND PURPOSE: Stroke mortality is decreasing in Sweden, as is the case in other Western European countries. However, both decreases and increases have been reported in Sweden for persons younger than age 65 years. The aim of this study was to compare the incidence of stroke in Sweden between the periods 1989 ... | ['Adult', 'Age Distribution', 'Age Factors', 'Aged', 'Female', 'Hospitalization', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Patient Discharge', 'Registries', 'Risk Factors', 'Sex Distribution', 'Sex Factors', 'Stroke', 'Sweden'] | 15,073,400 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.98... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Synthesis and Biological Evaluation of 12N-substituted Tricyclic Matrinic Derivatives as a Novel Family of Anti-Influenza Agents. | BACKGROUND: Influenza is still a serious threat to human health with significant morbidity and mortality, so it is desirable to develop novel anti-flu drug agents with novel structures.OBJECTIVE: The main purpose of this research was to explore broad-spectrum anti-flu agents and provide antiviral stockpiles in response... | ['Alkaloids', 'Animals', 'Antiviral Agents', 'Dogs', 'Influenza A Virus, H1N1 Subtype', 'Madin Darby Canine Kidney Cells', 'Male', 'Quinolizines', 'Rats, Sprague-Dawley', 'Structure-Activity Relationship'] | 29,473,520 | [['D03.132'], ['B01.050'], ['D27.505.954.122.388'], ['B01.050.150.900.649.313.750.250.216.200'], ['B04.820.480.968.405.400.214'], ['A11.251.210.827', 'A11.436.589'], ['D03.633.100.834'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[SURGICAL TREATMENT OF LOCALLY ADVANCED WELL DIFFERENTIATED THYROID CARCINOMA]. | AIMS: We aimed to better define the most appropriate therapeutic protocol for this type of tumor.BACKGROUND: The incidence of well-differentiated thyroid carcinoma is rising and the mortality from the disease remains low for patients with early disease. Nevertheless, the survival of patients with advanced disease has n... | ['Adenocarcinoma, Follicular', 'Carcinoma', 'Humans', 'Male', 'Prognosis', 'Retrospective Studies', 'Thyroid Neoplasms', 'Thyroidectomy', 'Treatment Outcome', 'Vocal Cord Paralysis'] | 28,971,654 | [['C04.557.470.200.025.060'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['C04.588.322.894', 'C04.58... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Impact of atorvastatin treatment on platelet-activating factor acetylhydrolase and 15-F(2trans)-isoprostane in hypercholesterolaemic patients. | AIMS: Isoprostanes are the product of free radical oxidation of arachidonic acid, whose hydrolysis from phospholipids is presumably catalysed by phospholipases A(2) (PLA(2)s) such as group IIA or V PLA(2)s, or group VII PLA(2)[platelet-activating factor acetylhydrolase (PAF-AH), lipoprotein-associated phospholipase]. A... | ['1-Alkyl-2-acetylglycerophosphocholine Esterase', 'Adult', 'Anticholesteremic Agents', 'Atorvastatin', 'Cholesterol, LDL', 'F2-Isoprostanes', 'Female', 'Heptanoic Acids', 'Humans', 'Hypercholesterolemia', 'Male', 'Middle Aged', 'Pyrroles'] | 17,214,829 | [['D08.811.277.352.100.680.750.937.249'], ['M01.060.116'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D03.383.129.578.075', 'D10.251.450.200'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['D10.251.355.255.100.375.500', 'D10.251.355.310.166.775.500', ... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pressure distribution at the stump/socket interface in transtibial amputees during walking on stairs, slope and non-flat road. | BACKGROUND: Studies examining the stump/socket interface stresses have been restricted to unsupported stance and natural gait, i.e. walking at a comfortable speed on flat and straight walkway. However, the pressure behaviour as to the interface in unilateral transtibial amputees during walking on stairs, slope and non-... | ['Adult', 'Amputation Stumps', 'Amputees', 'Equipment Failure Analysis', 'Gait', 'Humans', 'Knee Joint', 'Knee Prosthesis', 'Locomotion', 'Male', 'Pressure', 'Surface Properties', 'Tibia', 'Weight-Bearing'] | 16,919,376 | [['M01.060.116'], ['A01.378.100'], ['M01.150.100'], ['E05.325.192'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E07.695.400.410'], ['G07.568.500', 'G11.427.410.568'], ['G01.374.715'], ['G02.860'], ['A02.835.232.043.650.883'], ['G01.374.965']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A simple pain model for the evaluation of analgesic effects of NSAIDs in healthy subjects. | AIMS: Non-steroidal anti-inflammatory drugs (NSAIDs) are believed to counteract inflammation and inflammation-induced sensitization of nociceptors by inhibiting peripheral prostaglandin synthesis. We evaluated an experimental pain model for NSAIDs, that included an inflammatory component to mimic clinical inflammatory ... | ['Adult', 'Analgesics', 'Analysis of Variance', 'Anti-Inflammatory Agents, Non-Steroidal', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Hot Temperature', 'Humans', 'Male', 'Pain', 'Pain Threshold', 'Skin Temperature'] | 12,895,189 | [['M01.060.116'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sensitivity, Specificity and Predictive Value of Heart Rate Variability Indices in Type 1 Diabetes Mellitus. | BACKGROUND: Heart rate variability (HRV) indices may detect autonomic changes with good diagnostic accuracy. Type diabetes mellitus (DM) individuals may have changes in autonomic modulation; however, studies of this nature in this population are still scarce.OBJECTIVE: To compare HRV indices between and assess their pr... | ['Adolescent', 'Adult', 'Autonomic Nervous System', 'Case-Control Studies', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 1', 'Diabetic Neuropathies', 'Female', 'Heart Rate', 'Humans', 'Male', 'Reference Standards', 'Reference Values', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Statistics, Nonp... | 28,443,958 | [['M01.060.057'], ['M01.060.116'], ['A08.800.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C10.668.829.300', 'C19.246.099.937'], ['E01.370.600.8... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluating spatial distribution and seasonal variation of phthalates using passive air sampling in southern India. | Usage of phthalates as plasticizers has resulted in worldwide occurrence and is becoming a serious concern to human health and environment. However, studies on phthalates in Indian atmosphere are lacking. Therefore, we studied the spatio-temporal trends of six major phthalates in Tamil Nadu, southern India, using passi... | ['Adult', 'Air Pollutants', 'Air Pollution', 'Atmosphere', 'Child', 'Child, Preschool', 'Environmental Monitoring', 'Humans', 'India', 'Inhalation Exposure', 'Phthalic Acids', 'Plasticizers', 'Seasons'] | 27,979,682 | [['M01.060.116'], ['D27.888.284.101'], ['N06.850.460.100'], ['G16.500.275.063', 'N06.230.300.100'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['N06.850.460.350.112'], ['D02.241.223.805'], ['D27.720.760'], ['G01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
WISE 2005: responses of women to sublingual nitroglycerin before and after 56 days of 6° head-down bed rest. | This study tested the hypothesis that cardiovascular effects of sublingual nitroglycerin (NG) would be exaggerated after 56 days of 6° head-down bed rest (HDBR) in women, and that an aerobic and resistive exercise countermeasure (EX, n = 8) would reduce the effect compared with HDBR without exercise (CON, n = 7). Middl... | ['Administration, Sublingual', 'Adult', 'Bed Rest', 'Blood Flow Velocity', 'Blood Pressure', 'Cardiovascular Deconditioning', 'Female', 'Femoral Artery', 'Head-Down Tilt', 'Heart Rate', 'Humans', 'Middle Cerebral Artery', 'Nitroglycerin', 'Oxygen Consumption', 'Resistance Training', 'Stroke Volume', 'Ultrasonography, D... | 22,653,986 | [['E02.319.267.100.878'], ['M01.060.116'], ['E02.075'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.175'], ['A07.015.114.351'], ['G11.427.695.300'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.228.550'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Quantitative analysis of Actinomyces cell walls. | Quantitative data on the amino acid composition of cell walls of five species of Actinomyces were obtained by using a Beckman-Spinco amino acid analyzer. The major amino acids in A. israelii, A. naeslundii, A. eriksonii, and A. bovis species included alanine, glutamic acid, lysine, aspartic acid, and ornithine, as repo... | ['Actinomyces', 'Amino Acids', 'Cell Wall', 'Centrifugation', 'Chromatography', 'Culture Media', 'Microscopy, Electron', 'Microscopy, Phase-Contrast', 'Pepsin A', 'Trypsin'] | 4,881,955 | [['B03.510.024.049.050.050', 'B03.510.460.400.400.049.049.178'], ['D12.125'], ['A11.284.183'], ['E05.181'], ['E05.196.181'], ['D27.720.470.305', 'E07.206'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.350.515.513.569', 'E05.490.630.569', 'E05.595.513.569'], ['D08.811.277.656.074.500.700', 'D08.811.277.656.300.048... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Central hemodynamic monitoring in a woman with acute respiratory insufficiency after evacuation of a complete molar pregnancy. A case report. | BACKGROUND: The incidence of hydatiform moles in the United States is approximately 1 in 1,200 pregnancies. Acute respiratory insufficiency is a known complication of molar pregnancies, occurring in 8-11%. While there have been numerous case reports and retrospective studies describing respiratory complications followi... | ['Adolescent', 'Colloids', 'Female', 'Hemodynamics', 'Humans', 'Hydatidiform Mole', 'Monitoring, Physiologic', 'Osmotic Pressure', 'Pregnancy', 'Pulmonary Edema', 'Respiratory Insufficiency', 'Risk Factors', 'Uterine Neoplasms', 'Water-Electrolyte Balance'] | 11,725,738 | [['M01.060.057'], ['D20.280', 'D26.255.165'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.955.416.812', 'C04.850.908.416.750', 'C13.703.720.949.416.875'], ['E01.370.520'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['G08.686.784.769'], ['C08.381.742'], ['C08.618.846'], ['E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mepolizumab for severe eosinophilic asthma: a real-world snapshot on clinical markers and timing of response. | Background: Few studies have provided real-world evidence of mepolizumab efficacy and safety. We aimed to evaluate mepolizumab for severe eosinophilic asthma in daily clinical practice.Research design and methods: Patients included in the RINOVA (Interdisciplinary Network for the management of severe asthma in Veneto r... | ['Anti-Asthmatic Agents', 'Antibodies, Monoclonal, Humanized', 'Asthma', 'Biomarkers', 'Eosinophils', 'Exhalation', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Eosinophilia', 'Respiratory Function Tests', 'Treatment Outcome'] | 31,592,700 | [['D27.505.954.796.050'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D23.101'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['G09.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PBP5, PBP6 and DacD play different roles in intrinsic â-lactam resistance of Escherichia coli. | Escherichia coli PBP5, PBP6 and DacD, encoded by dacA, dacC and dacD, respectively, share substantial amino acid identity and together constitute ~50 % of the total penicillin-binding proteins of E. coli. PBP5 helps maintain intrinsic â-lactam resistance within the cell. To test if PBP6 and DacD play simlar roles, we d... | ['Escherichia coli', 'Escherichia coli Proteins', 'Gene Expression', 'Gene Expression Regulation, Bacterial', 'Mutation', 'Penicillin-Binding Proteins', 'Phenotype', 'Serine-Type D-Ala-D-Ala Carboxypeptidase', 'beta-Lactam Resistance'] | 21,719,544 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.297'], ['G05.308.300'], ['G05.365.590'], ['D08.811.710', 'D12.776.097.545'], ['G05.695'], ['D08.811.277.656.350.245.800', 'D08.811.277.656.959.560'], ['G06.099.225.500', 'G06.225.347.500', 'G07.690.773.984.269.347.500']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing quality of life in patients with schizophrenia in an acute psychiatric setting: reliability, validity and feasibility of the EQ-5D and the Q-LES-Q. | BACKGROUND: Quality of life (QoL) is considered an important outcome of treatment in psychiatry. Two QoL instruments, the EuroQoL-5D (EQ-5D) and the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), have been increasingly used among patients with schizophrenia.AIMS: The aim of this study was to invest... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Feasibility Studies', 'Female', 'Finland', 'Health Status Indicators', 'Humans', 'Inpatients', 'Male', 'Middle Aged', 'Quality of Life', 'Reproducibility of Results', 'Schizophrenia', 'Surveys and Questionnaires', 'Young Adult'] | 21,770,824 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['Z01.542.816.186'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sialidase activity and antibodies to sialidase-treated autologous erythrocytes in bronchoalveolar lavages from patients with idiopathic pulmonary fibrosis or sarcoidosis. | Sialidases catalyse the hydrolysis of terminal sialic acid of the carbohydrate moiety of glycoconjugates. Sialic acids play a key role in the expression or masking of antigenic sites and in cell-cell interactions. As an example, removal of sialic acid from the human erythrocyte membrane unmasks underlying molecules suc... | ['Adult', 'Aged', 'Autoantibodies', 'Bronchoalveolar Lavage Fluid', 'Erythrocytes', 'Female', 'Hemagglutination', 'Humans', 'Male', 'Middle Aged', 'Neuraminidase', 'Pulmonary Fibrosis', 'Sarcoidosis'] | 3,180,512 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['E05.927.100.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G02.111.026.500', 'G12.122.100.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adenosine system and cell calcium translocation: interference of calcium channel blockers. | Adenosine is able to inhibit in vitro neutrophil functions induced by formyl-methionyl-leucyl-phenylalanine (FMLP) and A23187, but not phorbol 12-myristate 13-acetate (PMA). The inhibiting activity on A23187 is reversed by increasing extracellular Ca2++ concentration. The calcium entry blocker flunarizine shows an acti... | ['Adenosine', 'Biological Transport', 'Calcium', 'Calcium Channel Blockers', 'Cell Membrane', 'Flunarizine', 'In Vitro Techniques', 'Magnetic Resonance Spectroscopy', 'Neutrophils'] | 2,226,674 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A11.284.149'], ['D03.383.606.450'], ['E05.481'], ['E05.196.867.519'], ['A11.118.637.415.583', 'A11.627.340.583'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of an acute myeloid leukaemia associated noncoding somatic mutation at 3' end of HOXA cluster. | Noncoding somatic mutations have been demonstrated to play important role in tumourigenesis. Here we show that there exists an acute myeloid leukaemia associated noncoding somatic mutation at 3' terminal of conserved HOXA cluster. The mutation was identified in the bone marrow blasts but not peripheral blood mononuclea... | ["3' Untranslated Regions", 'Alleles', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Homeodomain Proteins', 'Humans', 'Jumonji Domain-Containing Histone Demethylases', 'Leukemia, Myeloid, Acute', 'Leukemia, Promyelocytic, Acute', 'Mutation', 'Polymorphism, Single Nucleotide'] | 31,204,714 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['G05.360.340.024.340.030'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.662.582.475.50... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Removal of CO dehydrogenase from Pseudomonas carboxydovorans cytoplasmic membranes, rebinding of CO dehydrogenase to depleted membranes, and restoration of respiratory activities. | In Pseudomonas carboxydovorans, CO dehydrogenase and hydrogenase were found in association with the cytoplasmic membrane in a weakly bound and a tightly bound pool. The pools could be experimentally distinguished on the basis of resistance to removal by washes in low-ionic-strength buffer. The tightly bound pool of the... | ['Aldehyde Oxidoreductases', 'Cell Membrane', 'Centrifugation, Density Gradient', 'Kinetics', 'Multienzyme Complexes', 'Oxygen Consumption', 'Protein Binding', 'Pseudomonas', 'Solubility'] | 2,808,305 | [['D08.811.682.657.163'], ['A11.284.149'], ['E05.181.724.336', 'E05.196.941.336'], ['G01.374.661', 'G02.111.490'], ['D05.500.562', 'D08.811.600'], ['G03.680'], ['G02.111.679', 'G03.808'], ['B03.440.400.425.625.625', 'B03.660.250.580.590'], ['G02.805']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modelling the metabolism of protein secretion through the Tat route in Streptomyces lividans. | BACKGROUND: Streptomyces lividans has demonstrated its value as an efficient host for protein production due to its ability to secrete functional proteins directly to the media. Secretory proteins that use the major Sec route need to be properly folded outside the cell, whereas secretory proteins using the Tat route ap... | ['Bacterial Proteins', 'Glycoside Hydrolases', 'Metabolic Engineering', 'Metabolic Networks and Pathways', 'Models, Biological', 'Protein Folding', 'Streptomyces lividans', 'alpha-Amylases'] | 29,898,665 | [['D12.776.097'], ['D08.811.277.450'], ['E05.393.420.526', 'E05.481.500.311.249', 'J01.293.069.249.249'], ['G03.493'], ['E05.599.395'], ['G01.154.651', 'G02.111.688'], ['B03.300.390.400.810.768.500', 'B03.510.024.997.775.500', 'B03.510.415.400.810.768.500', 'B03.510.460.410.810.768.500'], ['D08.811.277.450.066.050']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Spirituality in the Catholic workplace. Does it differ from the now-fashionable versions found in other organizations? | "Spirituality in the workplace" has become something of a fad in corporate America as companies seek to find a balance between their employees' personal beliefs and the bottom line. Does this newfound spirituality-meets-margin differ from the spirituality traditionally observed in faith-based organizations? Often secul... | ['Catholicism', 'Commerce', 'Hospitals, Religious', 'Humans', 'Industry', 'Leadership', 'Motivation', 'Organizational Culture', 'Social Values', 'Spirituality', 'United States', 'Workplace'] | 15,926,420 | [['K01.844.188.250'], ['J01.219'], ['N02.278.421.481.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['F01.752.609'], ['F01.658', 'F01.752.543.500.750'], ['N04.452.606'], ['F01.829.873'], ['F02.880.705', 'K01.844.664.500'], ['Z01.107.567.875'], ['N01.824.245.925', 'N04.452.677.975']] | ['Humanities [K]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Olfaction and the homing ability of pigeons raised in a tropical area in Brazil. | Several workers have investigated the effect of anosmia on pigeon navigation in different geographical locations because it has been suggested that homing behavior is based on different cues, such as olfactory cues, the Earth's magnetic field or infrasound, and that in the absence of one cue another would be used. In t... | ['Animals', 'Brazil', 'Columbidae', 'Cues', 'Environment', 'Homing Behavior', 'Olfaction Disorders', 'Orientation', 'Smell'] | 15,562,449 | [['B01.050'], ['Z01.107.757.176'], ['B01.050.150.900.248.165.150'], ['F02.463.425.234'], ['G16.500.275', 'N06.230'], ['F01.145.113.646'], ['C10.597.751.600', 'C23.888.592.763.550'], ['F01.058.577', 'F02.830.606'], ['F02.830.816.643', 'G11.561.790.643']] | ['Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The Brief Accessibility, Responsiveness, and Engagement Scale: A Tool for Measuring Attachment Behaviors in Clinical Couples. | Measuring attachment behaviors is relevant to creating secure couple relationships. This article seeks to test and examine the reliability and validity of the Brief Accessibility, Responsiveness, and Engagement (BARE) Scale-a practical measure of couple attachment-in a clinical sample. Couples took the BARE and other a... | ['Adult', 'Communication', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Object Attachment', 'Personal Satisfaction', 'Psychometrics', 'Spouses', 'Surveys and Questionnaires'] | 26,748,730 | [['M01.060.116'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['F02.739.794.624'], ['F01.145.677'], ['F04.711.780'], ['F01.829.263.500.660', 'I01.880.853.150.500.670', 'M01.816'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
MICROPERIMETRY IN BEST VITELLIFORM MACULAR DYSTROPHY. | PURPOSE: To investigate retinal sensitivity in eyes with all the clinical stages of Best vitelliform macular dystrophy (VMD).METHODS: Thirty-two patients affected by VMD in subclinical, vitelliform, pseudohypopyon, vitelliruptive, and atrophic stages were enrolled in this prospective cross-sectional study. Patients und... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Scotoma', 'Visual Acuity', 'Visual Field Tests', 'Vitelliform Macular Dystrophy', 'Young Adult'] | 28,301,340 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.