Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Glutathione triggered degradation of polydopamine to facilitate controlled drug release for synergic combinational cancer treatment. | Here we report a novel mechanism for triggering drug release in the polydopamine (PDA)-coated magnetic CuCo2S4 core-shell nanostructure by glutathione (GSH) triggered degradation of PDA for release. In the design, we used PDA coated CuCo2S4 as the nanocarrier with polyethylene glycol and folic acid targeting molecules ... | ['Biocompatible Materials', 'Drug Synergism', 'Glutathione', 'Humans', 'Indoles', 'Neoplasms', 'Polymers'] | 31,465,074 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G07.690.773.968.477'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['C04'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. | BACKGROUND: Src has a critical role in tumor cell migration and invasion. Increased Src activity has been shown to correlate with disease progression and poor prognosis, suggesting Src could serve as a therapeutic target for kinase inhibition. Saracatinib (AZD0530) is a novel selective oral Src kinase inhibitor.METHODS... | ['Adenocarcinoma', 'Aged', 'Antineoplastic Agents', 'Benzodioxoles', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Protein Kinase Inhibitors', 'Quinazolines', 'Vascular Endothelial Growth Factor A', 'src-Family Kinases'] | 26,062,928 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D27.505.954.248'], ['D03.383.246.118', 'D03.633.100.115'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190'... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The response of hypoxic cells in SCCVII murine tumors to treatment with cisplatin and x rays. | Possible mechanisms of enhancement of radiation effects by cisplatin, including radiosensitization of hypoxic cells, drug-induced tumor reoxygenation, and inhibition of repair of sublethal radiation damage, were examined in the murine SCCVII model. Combination radiation/drug treatments were most effective when drug exp... | ['Animals', 'Carcinoma, Squamous Cell', 'Cell Hypoxia', 'Cisplatin', 'Combined Modality Therapy', 'Drug Evaluation, Preclinical', 'Humans', 'Infant', 'Mice', 'Mice, Inbred C3H', 'Oxygen Consumption', 'Radiation Tolerance', 'Skin Neoplasms'] | 1,991,687 | [['B01.050'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G03.197.300', 'G04.270.300'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.186'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.5... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of aroma-active compounds in Jiashi muskmelon juice by GC-O-MS and OAV calculation. | To identify aromatic compounds in Jiashi melon juice, gas chromatography-mass spectrometry-olfactometry (GC-MS-O) analysis was used. Odor activity values (OAVs) were also calculated on the basis of the qualitative and quantitative analysis of volatile compounds. Results showed that 42 volatiles were identified, among w... | ['Adult', 'Beverages', 'Cucumis melo', 'Female', 'Fruit', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Male', 'Odorants', 'Smell', 'Volatile Organic Compounds'] | 22,497,266 | [['M01.060.116'], ['G07.203.100', 'J02.200'], ['B01.650.940.800.575.912.250.300.188.444'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.275.640', 'N06.230.480'], ['F02.830.816.643', 'G11.561.790.643'], ['D02.974... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Left-Handed Metamaterial-Inspired Unit Cell for S-Band Glucose Sensing Application. | This paper presents an oval-shaped sensor design for the measurement of glucose concentration in aqueous solution. This unit cell sensing device is inspired by metamaterial properties and is analytically described for better parametric study. The mechanism of the sensor is a sensing layer with varying permittivity plac... | ['Biosensing Techniques', 'Computer Simulation', 'Glucose', 'Humans', 'Microwaves', 'Software', 'Water'] | 30,621,259 | [['E05.601.043'], ['L01.224.160'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['L01.224.900'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Flowable materials as an intermediate layer could improve the marginal and internal adaptation of composite restorations in Class-V-cavities. | OBJECTIVES: The purpose of this in vitro study was to evaluate the marginal and internal adaptation of restorative systems in combination with flowable materials as an intermediate layer in Class-V-cavities.METHODS: Thirty Class-V-cavities with occlusal margins in enamel and gingival margins in dentin/cementum were pre... | ['Compomers', 'Composite Resins', 'Dental Cavity Preparation', 'Dental Cementum', 'Dental Enamel', 'Dental Marginal Adaptation', 'Dental Materials', 'Dental Restoration, Permanent', 'Dentin', 'Dentin-Bonding Agents', 'Humans', 'Materials Testing', 'Methacrylates', 'Microscopy, Electron, Scanning', 'Polymethacrylic Acid... | 16,084,584 | [['D05.750.716.822.308.300', 'D25.339.291.150', 'D25.339.816.500.300', 'D25.720.716.822.308.300', 'J01.637.051.339.291.150', 'J01.637.051.339.816.500.300', 'J01.637.051.720.716.822.308.300'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Relation of right ventricular mass and volume to functional health status in repaired tetralogy of Fallot. | After repair of tetralogy of Fallot, right ventricular (RV) mass and mass:volume ratio may reflect RV remodeling and adverse outcomes. This study aimed to evaluate the relation of RV mass to functional health status and subsequent adverse RV remodeling and to determine whether RV mass measurement in systole could impro... | ['Adult', 'Cardiac Surgical Procedures', 'Cardiac Volume', 'Cross-Sectional Studies', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Health Status', 'Heart Ventricles', 'Humans', 'Magnetic Resonance Imaging, Cine', 'Male', 'Myocardial Contraction', 'Prognosis', 'Retrospective Studies', 'Severity of Illness Inde... | 25,438,919 | [['M01.060.116'], ['E04.100.376', 'E04.928.220'], ['G09.330.380.249'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.240.425', 'N01.224.425', 'N06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Observations from a national multiple institution autotransfusion (ATS) quality indicator program. | A process to collect universal, mandatory autotransfusion (ATS) procedure quality indicators to measure and monitor ATS quality improvement was designed and implemented by Fresenius Medical Care Extracorporeal Alliance (FMCEA) an outsource provider of extracorporeal services. The indicator program collected and evaluat... | ['Benchmarking', 'Blood Transfusion, Autologous', 'Cardiac Surgical Procedures', 'Extracorporeal Circulation', 'Hospitals', 'Humans', 'Program Evaluation', 'Quality Indicators, Health Care', 'Total Quality Management', 'United States'] | 15,334,756 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['E02.095.135.164'], ['E04.100.376', 'E04.928.220'], ['E04.292'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N04.761.789', 'N05.715.760'], ['N04.4... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Biosynthesis and Characterization of Zearalenone-14-Sulfate, Zearalenone-14-Glucoside and Zearalenone-16-Glucoside Using Common Fungal Strains. | Zearalenone (ZEN) and its phase II sulfate and glucoside metabolites have been detected in food and feed commodities. After consumption, the conjugates can be hydrolyzed by the human intestinal microbiota leading to liberation of ZEN that implies an underestimation of the true ZEN exposure. To include ZEN conjugates in... | ['Aspergillus oryzae', 'Fusarium', 'Glucosides', 'Rhizopus', 'Sulfates', 'Zearalenone'] | 29,494,480 | [['B01.300.381.081.500'], ['B01.300.381.366'], ['D09.408.348'], ['B01.300.300.500.800'], ['D01.248.497.158.845', 'D01.875.800.800.850'], ['D02.455.426.559.389.657.852.900', 'D02.540.950', 'D23.946.587.989']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognostic indices for tumor relapse and tumor mortality in follicular thyroid carcinoma. | To establish an objective basis for therapeutic decisions and follow-up programs in patients with follicular thyroid cancer, the authors developed a prognostic scoring system. The prognostic impact of nine clinical, histologic, and therapeutic parameters was quantified retrospectively based on a multivariate analysis c... | ['Adult', 'Aged', 'Aging', 'Carcinoma', 'Female', 'Follow-Up Studies', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neck Dissection', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Prognosis', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Survival Analysis', 'Survival Rate... | 2,004,304 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['C04.557.470.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Saccharomyces cerevisiae PHM8 gene encodes a soluble magnesium-dependent lysophosphatidic acid phosphatase. | Phosphate is the essential macronutrient required for the growth of all organisms. In Saccharomyces cerevisiae, phosphatases are up-regulated, and the level of lysophosphatidic acid (LPA) is drastically decreased under phosphate-starved conditions. The reduction in the LPA level is attributed to PHM8, a gene of unknown... | ['Amino Acid Motifs', 'Gene Deletion', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Lysophospholipids', 'Magnesium', 'Mutagenesis, Site-Directed', 'Phosphates', 'Phosphoric Monoester Hydrolases', 'Protein Structure, Tertiary', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 18,234,677 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G02.300'], ['G02.380'], ['D10.570.755.375.760.550'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.393.420.601.575'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autonomic neuropathy influences great toe blood pressure. | OBJECTIVE: To assess the influence of autonomic neuropathy on toe blood pressure (TBP), a parameter used currently as an ischemic index.RESEARCH DESIGN AND METHODS: The age-matched study subjects included 20 non-insulin-dependent diabetes mellitus (NIDDM) patients with autonomic neuropathy (DN) and 10 NIDDM patients wi... | ['Analysis of Variance', 'Ankle', 'Autonomic Nervous System', 'Blood Gas Monitoring, Transcutaneous', 'Blood Pressure', 'Diabetes Mellitus, Type 2', 'Diabetic Neuropathies', 'Humans', 'Hypotension, Orthostatic', 'Middle Aged', 'Oxygen', 'Partial Pressure', 'Posture', 'Regression Analysis', 'Respiration', 'Systole', 'Th... | 8,026,283 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A01.378.610.050'], ['A08.800.050'], ['E01.370.225.124.100.100.600.100', 'E01.370.370.380.600.100', 'E01.370.386.700.100.600.100', 'E05.200.124.100.100.600.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C18.452.394.750.149', 'C19.246.300'], ['C1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Complete amino acid sequence of Scytalidium lignicolum acid protease B. | The acid protease B (SLB) of Scytalidium lignicolum was reduced and carboxymethylated and then subjected to tryptic digestion. Five fragments were isolated and some of them were further digested with alpha-chymotrypsin, thermolysin, and dilute acetic acid. The sequence analysis of these fragments and the peptides by co... | ['Amino Acid Sequence', 'Aspartic Acid Endopeptidases', 'Chymotrypsin', 'Disulfides', 'Endopeptidases', 'Hydrolysis', 'Mitosporic Fungi', 'Peptide Fragments'] | 6,370,989 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D08.811.277.656.300'], ['G02.380'], ['B01.300.381'], ['D12.644.541']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Dental caries rates in primary teeth in 2002, and caries surveillance trends 1981-2002, in a South African city. | OBJECTIVE: To determine trends in the prevalence and severity of dental caries in 2- to 5-year-old children.BASIC RESEARCH DESIGN: Repeated cross-sectional surveys in 1981, 1983, 1985, 1987, 1989, 1991, 1994, 1997 and 2002.CLINICAL SETTING: Nursery schools in Germiston, South Africa.PARTICIPANTS: Dental caries was diag... | ['Analysis of Variance', 'Child, Preschool', 'Cross-Sectional Studies', 'DMF Index', 'Dental Caries', 'Epidemiology', 'Female', 'Humans', 'Logistic Models', 'Male', 'Population Surveillance', 'Prevalence', 'South Africa', 'Tooth, Deciduous'] | 18,637,318 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['C07.793.720.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Human cytomegalovirus strain Towne pp28 gene: sequence comparison to pp28 of HCMV AD169 and stable expression in Chinese hamster ovary cells. | Human cytomegalovirus (HCMV) contains a 28-kDa (pp28) matrix phosphoprotein which has been shown to be highly immunogenic in humans. We have cloned and sequenced the gene encoding pp28 of HCMV Towne strain (pp28Towne) and have expressed this gene in stable Chinese hamster ovary (CHO) cell lines in order to examine the ... | ['Animals', 'Base Sequence', 'Blotting, Northern', 'Cell Line', 'Cloning, Molecular', 'Cricetinae', 'Cytomegalovirus', 'DNA, Viral', 'Genes, Viral', 'Molecular Sequence Data', 'Phosphoproteins', 'RNA, Messenger', 'RNA, Viral', 'Restriction Mapping', 'Solubility', 'Viral Proteins', 'Viral Structural Proteins'] | 1,653,497 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A11.251.210'], ['E05.393.220'], ['B01.050.150.900.649.313.992.635.075.250'], ['B04.280.382.150.150'], ['D13.444.308.568'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Advanced tool for characterization of microbial cultures by combining cytomics and proteomics. | Flow cytometry approaches are applicable to recover sub-populations of microbial cultures in a purified form. To examine the characteristics of each sorted cell population, Omics technologies can be used for comprehensively monitoring cellular physiology, adaptation reactions, and regulated processes. In this study, we... | ['Bacterial Load', 'Bacterial Proteins', 'Cell Separation', 'Chromatography, Liquid', 'Escherichia coli K12', 'Flow Cytometry', 'Mass Spectrometry', 'Proteome', 'Proteomics', 'Pseudomonas putida'] | 20,676,634 | [['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['D12.776.097'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.196.181.400'], ['B03.440.450.425.325.300.360', 'B03.660.250.150.180.100.360'], ['E01.370.225.500.363.342', 'E01.370.225.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of nitric oxide synthase isoform deletion on oxytocin and vasopressin messenger RNA in mouse hypothalamus. | The effects of neuronal, endothelial, or inducible nitric oxide synthase gene disruption on the expression of oxytocin and vasopressin gene were examined in the hypothalamus (paraventricular, supraoptic, suprachiasmatic, and anterior commissural nuclei) and extrahypothalamus (bed nucleus of the stria terminalis). The o... | ['Animals', 'Gene Deletion', 'Hypothalamus', 'Isoenzymes', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nerve Tissue Proteins', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type I', 'Oxytocin', 'RNA, Messenger', 'Vasopressins'] | 15,729,148 | [['B01.050'], ['G05.365.590.762.320', 'G05.558.800.320'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.150.900.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A neuropathological, stereo-EEG, and MRI study of subcortical band heterotopia. | The authors performed an MRI, stereo-EEG, and pathology study on a woman with subcortical band heterotopia and partial epilepsy. Clinical manifestations of seizures always started when ictal discharges were present in outer and heterotopic cortices. Simultaneous activation of both cortices and presence of differentiate... | ['Adult', 'Cerebral Cortex', 'Choristoma', 'Electroencephalography', 'Epilepsies, Partial', 'Female', 'Humans', 'Magnetic Resonance Imaging'] | 12,796,544 | [['M01.060.116'], ['A08.186.211.200.885.287.500'], ['C23.300.250'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Elevated sleep arousal thresholds in enuretic boys: clinical implications. | Enuretic children are described as difficult to arouse from sleep. We studied auditory sleep arousal thresholds in enuretic boys and report on the clinical implications of these findings. Fifteen enuretic and 18 control subjects (7-12-year-old males) were studied in a sleep laboratory for four consecutive nights using ... | ['Arousal', 'Case-Control Studies', 'Chi-Square Distribution', 'Child', 'Enuresis', 'Humans', 'Longitudinal Studies', 'Male', 'Sleep Stages', 'Sleep Wake Disorders'] | 9,174,224 | [['F02.830.104', 'G11.561.035'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['C12.777.934.284', 'C13.351.968.934.252', 'F01.145.126.856', 'F03.388.400'], ['B01.050.150.900.6... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Susceptibility of Ceratitis capitata Wiedemann (Diptera: Tephritidae) to entomopathogenic fungi. | The Mediterranean fruit fly Ceratitis capitata (Wiedemann) is one of the most serious pest of fruits in Syria and present all year round. This fly is active on different host plants, such as mango, peach, fig, apple, pear, and citrus. The number of generations per year varies with local temperatures and host plant. The... | ['Animals', 'Ceratitis capitata', 'Fungi', 'Lethal Dose 50', 'Paecilomyces', 'Pest Control, Biological', 'Pupa'] | 19,226,799 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.850.150'], ['B01.300'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['B01.300.381.640'], ['N06.850.780.200.650.650'], ['B05.500.700', 'G07.345.500.550.500.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endotoxin-induced tumor necrosis factor (TNF): selective triggering of TNF and interleukin-1 production by distinct glucosamine-derived lipids. | The isolated lipid A of Bordetella pertussis endotoxin (LipA) has been found to induce in vitro release of tumor necrosis factor (TNF) by murine macrophages, albeit much less efficiently than does the intact lipopolysaccharide. Synthetic analogs (monosaccharides M4 and M6) of both glucosamine units present in the LipA ... | ['Animals', 'Calcimycin', 'Endotoxins', 'Galactosamine', 'Glucosamine', 'Interleukin-1', 'Lipopolysaccharides', 'Macrophage Activation', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred A', 'Mice, Inbred C3H', 'Phospholipids', 'Structure-Activity Relationship', 'Tumor Necrosis Factor-alpha', 'Virulence Factors, Bordetella'... | 3,135,943 | [['B01.050'], ['D03.633.100.221.173'], ['D23.946.123.329'], ['D09.067.342.356'], ['D09.067.342.531'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The antishock pelvic clamp. | Unstable posterior pelvic ring disruptions are frequently accompanied by severe venous bleeding and hypotension. Mechanical stabilization has been shown to help reduce such blood loss. A new external fixator called an antishock clamp provides direct reduction and compression of such fracture-diastases about the sacroil... | ['Adult', 'Emergencies', 'External Fixators', 'Fractures, Bone', 'Humans', 'Male', 'Pelvic Bones', 'Shock, Hemorrhagic'] | 2,044,295 | [['M01.060.116'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825'], ['C23.550.414.980', 'C23.550.835.650']] | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Living donor liver transplantation for hepatocellular carcinoma: Tokyo University series. | BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is one of the major indications for living donor liver transplantation (LDLT). Unlike in deceased donor liver transplantation, however, there exist no universally adopted selection criteria for the potential candidates with HCC in LDLT. Our institutional guideline for HCC... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Female', 'Humans', 'Japan', 'Liver Neoplasms', 'Liver Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Patient Selection', 'Survival Analysis'] | 17,960,065 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. | Recent studies have shown that myostatin, first identified as a negative regulator of skeletal muscle growth, may also be involved in the formation of fibrosis within skeletal muscle. In this study, we further explored the potential role of myostatin in skeletal muscle fibrosis, as well as its interaction with both tra... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Decorin', 'Extracellular Matrix Proteins', 'Female', 'Fibroblasts', 'Fibrosis', 'Follistatin', 'Mice', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Muscular Diseases', 'Myoblasts', 'Myostatin', 'NIH 3T3 Cells', 'Proteoglycans', 'Recombinant Proteins', 'Trans... | 17,597,062 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['D09.698.735.700.750', 'D12.776.395.650.750.625', 'D12.776.395.650.875.500', 'D12.776.860.300.806.750'], ['D12.776.860.300'], ['A11.329.228'], ['C23.550.355'], ['D12.776.157.247'], ['B01.050.150.900.649.313.992.635.505.500'], ['A10.690.552.500.500', 'A... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the use of cultured cells in a bioassay for parathyroid hormone. | Measurement of parathyroid hormone (PTH) is important for diagnosing hyper- and hypoparathyroidism. The move to two-site immunometric assays that detect the whole molecule has improved the discrimination of these conditions but these assays may be too restrictive because some PTH fragments that are biologically active ... | ['Animals', 'Biological Assay', 'Cats', 'Cattle', 'Cells, Cultured', 'Chlorocebus aethiops', 'Cricetinae', 'Dogs', 'Evaluation Studies as Topic', 'Glioma', 'Humans', 'Kidney', 'Marsupialia', 'Mesocricetus', 'Neuroblastoma', 'Opossums', 'Parathyroid Hormone', 'Swine'] | 7,829,991 | [['B01.050'], ['E05.091'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.337', 'N05.715.360.335'], ['C04.557.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An improved assay for iduronate 2-sulphate sulphatase in serum and its use in the detection of carriers of the Hunter syndrome. | A more sensitive assay procedure has been developed for the enzyme iduronate 2-sulphate sulphatase which is deficient in the Hunter syndrome. The substrate is the same as previously described by Lim et al. [1], O-(alpha-L-idopyranosyluronic acid 2-sulphate)-(1leads to 4)-2,5 anhydro-D-[3H-1]mannitol 6-sulphate, but, af... | ['Chromatography, Ion Exchange', 'Clinical Enzyme Tests', 'Genetic Carrier Screening', 'Hair', 'Homozygote', 'Humans', 'Iduronate Sulfatase', 'Kinetics', 'Mucopolysaccharidosis II', 'Sulfatases'] | 6,786,801 | [['E05.196.181.400.383'], ['E01.370.225.124.200', 'E05.196.427.200', 'E05.200.124.200'], ['E01.370.225.562.250', 'E05.200.562.250', 'E05.393.435.250', 'N02.421.308.200', 'N02.421.726.233.221.250'], ['A17.360'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.827.500'], ['G01.374.661'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Disc and condyle translation in patients with temporomandibular disorder. | OBJECTIVE: The purpose of this study was to elucidate causal relationship between disc and condyle range of movement and clinical signs and symptoms in patients with temporomandibular disorders (TMD), using magnetic resonance imaging (MRI).STUDY DESIGN: The subjects comprised of a study group of 191 patients with TMD a... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Chi-Square Distribution', 'Facial Pain', 'Female', 'Humans', 'Joint Dislocations', 'Magnetic Resonance Imaging', 'Male', 'Mandibular Condyle', 'Middle Aged', 'Osteoarthritis', 'Pain Measurement', 'Range of Motion, Articular', 'Statistics, Non... | 15,829,887 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C23.888.592.612.330'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of sequential video shot comprehensibility on attentional synchrony: A comparison of children and adults. | To comprehend edited video, viewers must infer the meaning conveyed by successive video shots (i.e., continuous video segments separated by edit points, such as camera cuts). The central question here was whether comprehension-related top-down cognitive processes drive eye movements during sequential processing of vide... | ['Adult', 'Attention', 'Child, Preschool', 'Comprehension', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Multimedia'] | 30,275,303 | [['M01.060.116'], ['F02.830.104.214'], ['M01.060.406.448'], ['F02.463.188.357'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.633', 'L01.178.820.090.633']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Multi-output Model with Box-Jenkins Operators of Quadratic Indices for Prediction of Malaria and Cancer Inhibitors Targeting Ubiquitin- Proteasome Pathway (UPP) Proteins. | The ubiquitin-proteasome pathway (UPP) is the primary degradation system of short-lived regulatory proteins. Cellular processes such as the cell cycle, signal transduction, gene expression, DNA repair and apoptosis are regulated by this UPP and dysfunctions in this system have important implications in the development ... | ['Antimalarials', 'Antineoplastic Agents', 'Computational Biology', 'Databases, Pharmaceutical', 'Drug Discovery', 'Humans', 'Malaria', 'Molecular Targeted Therapy', 'Neoplasms', 'Proteasome Endopeptidase Complex', 'Proteolysis', 'Ubiquitin'] | 26,427,384 | [['D27.505.954.122.250.100.085'], ['D27.505.954.248'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.400', 'L01.470.750.750.400'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530', 'C01.920.875'], ['E02.319.574'], ['C04'], ['D... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Quantitative power Doppler ultrasound measures of peripheral joint synovitis in poor prognosis early rheumatoid arthritis predict radiographic progression. | OBJECTIVE: To assess the value of quantitative vascular imaging by power Doppler US (PDUS) as a tool that can be used to stratify patient risk of joint damage in early seropositive RA while still biologic naive but on synthetic DMARD treatment.METHODS: Eighty-five patients with seropositive RA of <3 years duration had ... | ['Adolescent', 'Adult', 'Aged', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Disease Progression', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Metacarpophalangeal Joint', 'Middle Aged', 'Prognosis', 'Reproducibility of Results', 'Severity of Illness Index', 'Synovitis', 'Ultrasonography, Doppler', '... | 26,316,580 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['A02.835.583.405.500'], ['M01.060.116.630'], ['E01.789'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A direct comparison between ERP and fMRI measurements of food-related inhibitory control: Implications for BMI status and dietary intake. | Obesity and maintaining a healthy diet have important implications for physical and mental health. One factor that may influence diet and obesity is inhibitory control. We tested how N2 and P3 amplitude, event-related potential (ERP) components that reflect inhibitory control, and functional magnetic resonance imaging ... | ['Adolescent', 'Adult', 'Body Mass Index', 'Cerebral Cortex', 'Eating', 'Electroencephalography', 'Evoked Potentials', 'Executive Function', 'Feeding Behavior', 'Female', 'Food', 'Functional Neuroimaging', 'Humans', 'Inhibition, Psychological', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Obesity', 'Overweight... | 29,113,942 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A08.186.211.200.885.287.500'], ['G07.203.650.283', 'G10.261.330'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.463.217'], ['F01.145.113.547', 'F01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Understanding the magnitude of still birth in Mymensingh Medical College Hospital. | To understand the incidence and causes of still-births occurred in Mymensingh Medical College Hospital, we conducted a retrospective record review study in Department of Gynaecology of the hospital. The study population were the cases of still births occurred the months of January and December 2007. We administered a s... | ['Bangladesh', 'Cause of Death', 'Female', 'Fetal Distress', 'Humans', 'Incidence', 'Obstetric Labor Complications', 'Pregnancy', 'Pregnancy Complications', 'Retrospective Studies', 'Risk Factors', 'Seasons', 'Stillbirth'] | 20,639,823 | [['Z01.252.245.131'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C23.888.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C1... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Open tongue-type calcaneus fracture with a partial posteromedial subtalar dislocation. | Calcaneus fractures with a subtalar dislocation are extremely rare. A case of a tongue-type calcaneus fracture with a posteromedial dislocation of the calcaneal posterior facet and tuberosity is presented. Treatment included lag screw fixation to maintain the reduction without further soft-tissue trauma. | ['Accidental Falls', 'Bone Screws', 'Calcaneus', 'Debridement', 'Female', 'Fracture Fixation', 'Fractures, Open', 'Humans', 'Joint Dislocations', 'Middle Aged', 'Radiography'] | 10,955,468 | [['N06.850.135.122'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A02.835.232.043.300.710.300'], ['E04.176'], ['E04.555.300'], ['C26.404.311'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['M01.060.116.630'], ['E01.370.350.700']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sex hormones selectively impact the endocervical mucosal microenvironment: implications for HIV transmission. | Several studies suggest that progesterone and estrogens may affect HIV transmission in different, possibly opposing ways. Nonetheless, a direct comparison of their effects on the mucosal immune system has never been done. We hypothesize that sex hormones might impact the availability of cells and immune factors importa... | ['Animals', 'CD4-Positive T-Lymphocytes', 'Cervix Uteri', 'Chemokine CCL21', 'Chemokine CCL4', 'Endometrium', 'Estradiol', 'Estrogens', 'Female', 'Gene Expression', 'HIV Infections', 'Integrin alpha4', 'Integrin beta Chains', 'Macaca mulatta', 'Medroxyprogesterone Acetate', 'Mucins', 'Mucous Membrane', 'Receptors, CCR5... | 24,830,732 | [['B01.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A05.360.319.679.256'], ['D12.644.276.374.200.110.890', 'D12.776.467.374.200.110.890', 'D23.125.300.110.890', 'D23.469.200.110.890', 'D23.529.374.200.110.890'], ['D12.644.276.374.200.110.200', 'D12.644.276.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Funding issues and options for pharmacists providing sessional services to rural hospitals in Australia. | OBJECTIVE: Many of Australia' s rural hospitals operate without an on-site pharmacist. In some, community pharmacists have sessional contracts to provide medication management services to inpatients. This paper discusses the funding arrangements of identified sessional employment models to raise awareness of options fo... | ['Australia', 'Employment', 'Female', 'Health Services Accessibility', 'Hospitals, Rural', 'Humans', 'Male', 'Pharmacists', 'Qualitative Research'] | 25,556,894 | [['Z01.639.100', 'Z01.678.100.373'], ['N01.824.245'], ['N04.590.374.350', 'N05.300.430'], ['N02.278.421.518'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.780', 'N02.360.780'], ['H01.770.644.241.850']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Separation and preconcentration of trace amounts of aluminum ions in surface water samples using different analytical techniques. | A separation/preconcentration of aluminum (III) (Al(3+)) has been developed to overcome the problem of high matrix species, which may interfere with the determination of trace quantity of Al(3+) in natural water samples. The separation of Al(3+) in water samples was carried out from interfering cations by complexing th... | ['Adsorption', 'Aluminum', 'Environmental Monitoring', 'Fresh Water', 'Hydrogen-Ion Concentration', 'Octoxynol', 'Oxyquinoline', 'Polyethylene Glycols', 'Quinaldines', 'Reproducibility of Results', 'Solid Phase Extraction', 'Spectrometry, Fluorescence', 'Spectrophotometry, Atomic', 'Water Pollutants, Chemical'] | 19,782,206 | [['G01.030', 'G02.020'], ['D01.268.557.050', 'D01.552.547.050'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.280', 'N06.230.232'], ['G02.300'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.637.051.720.741.610'], ['D03.633.100.810.350.625'], ['D02.033.455.250.700', 'D05.750.741', ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Cow-related risk factors for milk leakage. | Milk leakage in dairy cows is a symptom of impaired teat sphincter function. Milk leakage is related to an increased risk of mastitis in heifers and cows, and causes hygiene problems. The aim of our study was to assess whether teat shape, condition of teat orifice, and peak milk flow rate are risk factors for milk leak... | ['Animals', 'Cattle', 'Cattle Diseases', 'Female', 'Germany', 'Lactation', 'Logistic Models', 'Longitudinal Studies', 'Mammary Glands, Animal', 'Mastitis, Bovine', 'Risk Factors'] | 15,591,375 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['Z01.542.315'], ['G08.686.523', 'G08.686.702.500'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830.500.... | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Ontogeny of secretory immunity: levels of secretory IgA and natural antibodies in saliva. | In 187 healthy subjects from 2 months to 27 years of age, secretory IgA and free secretory component were assayed in samples of whole saliva obtained before and after stimulation with lemon juice. Antibody titers against Escherichia coli O antigens and against rabbit erythrocytes were also dosed in unstimulated saliva.... | ['Adolescent', 'Adult', 'Antibodies', 'Antibodies, Bacterial', 'Child', 'Child, Preschool', 'Erythrocytes', 'Escherichia coli', 'Humans', 'Immunoglobulin A', 'Immunoglobulin A, Secretory', 'Infant', 'Saliva', 'Secretory Component'] | 7,008,011 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['M01.060.406'], ['M01.060.406.448'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B03.440.450.425.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Membrane permeation of testosterone from either solutions, particle dispersions, or particle-stabilized emulsions. | We derive a unified model that accounts for the variation in extent and rate of membrane permeation by a permeating species with the type of donor compartment formulation (aqueous and oil solutions, particle dispersions, and oil-in-water and water-in-oil emulsions stabilized by particles) initially containing the perme... | ['Dimethylpolysiloxanes', 'Emulsions', 'Membranes, Artificial', 'Myristates', 'Particle Size', 'Solubility', 'Solutions', 'Surface Properties', 'Testosterone', 'Water'] | 22,224,415 | [['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['D20.280.260', 'D26.255.165.260'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D10.251.640.610'], ['G02.712'], ['G02.805'], ['D26.776'], ['G02.860'], ['D04.210.500.054.079.429.824', 'D06.472.334.851.968.984'... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Gemmobacter intermedius sp. nov., isolated from a white stork (Ciconia ciconia). | A cream-coloured, Gram-stain-negative, aerobic, non-motile, rod- to irregular shaped bacterium, strain 119/4(T), was isolated from a choana swab of a white stork nestling on sheep blood agar. 16S rRNA gene sequence analysis and subsequent comparisons showed that it was a member of the family Rhodobacteraceae, showing 9... | ['Animals', 'Bacterial Typing Techniques', 'Base Composition', 'Birds', 'DNA, Bacterial', 'Fatty Acids', 'Molecular Sequence Data', 'Phylogeny', 'Poland', 'Putrescine', 'RNA, Ribosomal, 16S', 'Rhodobacteraceae', 'Sequence Analysis, DNA', 'Spermidine', 'Ubiquinone'] | 25,479,954 | [['B01.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['B01.050.150.900.248'], ['D13.444.308.212'], ['D10.251'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['Z01.542.248.679'], ['D02.092.211.415.701', 'D02.092.782.258.784'], ['D13.444.735.686.670'], ['B03.660.050.750'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Phosphoester hydrolysis by cerium(IV)-thiacalix[4]arene complexes and its application to immunoassay. | Thiacalix[4]arenetetrasulfonate was treated with Ce(IV) in water at pH 9.5 to give novel phosphoester-hydrolyzing complexes. The dinuclear Ce(IV) complex promoted the hydrolysis of p-nitrophenyl phosphate with a turnover frequency of 6.8 h(-1) at 50 degrees C, showing fourfold higher activity than the mononuclear compl... | ['Animals', 'Bence Jones Protein', 'Calibration', 'Calixarenes', 'Catalysis', 'Esters', 'Humans', 'Hydrolysis', 'Immunoassay', 'Immunoglobulin G', 'Molecular Structure', 'Nitrophenols', 'Organometallic Compounds', 'Organophosphorus Compounds', 'Rabbits'] | 19,404,618 | [['B01.050'], ['D12.776.124.486.485.900.120', 'D12.776.124.790.651.900.120', 'D12.776.377.715.548.900.120'], ['E05.978.155'], ['D04.345.025'], ['G02.130'], ['D02.241.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['E05.478.566', 'E05.601.470'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epigenomic differentiation in mouse preimplantation nuclei of biparental, parthenote and cloned embryos. | Chromosomes, sub-chromosomal regions and genes are repositioned during cell differentiation to acquire a cell-type-specific spatial organization. The constraints that are responsible for this cell-type-specific spatial genome positioning are unknown. In this study we addressed the question of whether epigenetic genome ... | ['Animals', 'Cell Differentiation', 'Cell Nucleus', 'Cell Nucleus Structures', 'Cloning, Organism', 'Embryo Implantation', 'Embryo, Mammalian', 'Epigenesis, Genetic', 'Fertilization in Vitro', 'Genomics', 'Mice', 'Nuclear Transfer Techniques', 'Parthenogenesis', 'Reproductive Techniques'] | 17,447,149 | [['B01.050'], ['G04.152'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279'], ['E05.393.240', 'E05.820.180'], ['G08.686.784.170.104.500'], ['A16.254'], ['G05.308.203'], ['E02.875.800.750', 'E05.820.800.750'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
CD40 ligand+ microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis a potential mechanism for intraplaque neovascularization. | OBJECTIVES: Our goal was to demonstrate that microparticles (MPs) are the endogenous signal leading to neovessel formation through CD40 ligation in human atherosclerotic plaques.BACKGROUND: Vulnerable atherosclerotic plaques prone to rupture are characterized by an increased number of vasa vasorum and frequent intrapla... | ['Aged', 'Apoptosis', 'Atherosclerosis', 'CD40 Ligand', 'Carotid Artery Diseases', 'Cell Proliferation', 'Cells, Cultured', 'Culture Media', 'Endarterectomy', 'Endothelium, Vascular', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Flow Cytometry', 'Humans', 'Male', 'Neovascularization, Pathologic', 'Particle Size', 'R... | 18,929,241 | [['M01.060.116.100'], ['G04.146.954.035'], ['C14.907.137.126.307'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['C10.228.140.300.200', 'C14.907.253.123'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D27.720.470.305', 'E07.206']... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Importance of inhaler device use status in the control of asthma in adults: the asthma inhaler treatment study. | BACKGROUND: Proper education and training in correct inhalation technique has been reported to have a substantial role in the achievement of optimal therapeutic benefit and asthma control. The present study was designed to evaluate inhaler technique and the role of education in relation to asthma control among patients... | ['Adolescent', 'Adult', 'Anti-Asthmatic Agents', 'Asthma', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nebulizers and Vaporizers', 'Patient Compliance', 'Patient Education as Topic', 'Prospective Studies', 'Registries', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Turkey', 'Young Adult'] | 23,882,109 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.796.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.605'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['I02.233.332.500', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34betaE12 to discriminate cancer in prostatic epithelium. | In select cases of prostatic carcinoma, antikeratin 34betaE12 immunohistochemical analysis is diagnostically useful for specific labeling of basal cells. This antibody, however, is prone to variability in staining, and the optimal conditions were not, to our knowledge, previously defined. We combined steam heat with ED... | ['Antibodies, Monoclonal', 'Buffers', 'Edetic Acid', 'Hot Temperature', 'Humans', 'Immunohistochemistry', 'Keratins', 'Male', 'Prostatic Intraepithelial Neoplasia', 'Prostatic Neoplasms', 'Staining and Labeling', 'Steam'] | 9,950,154 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.720.470.280'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Unhealthy alcohol use in primary care patients who screen positive for drug use. | BACKGROUND: Unhealthy alcohol use (UAU) is common among people who use other drugs; however, little information is available about UAU among patients who screen positive for drugs in primary care, where the clinical priority might be assumed to be drug use. This study aimed at describing the occurrence of UAU and its a... | ['Adult', 'Alcohol Drinking', 'Female', 'Humans', 'Male', 'Primary Health Care', 'Randomized Controlled Trials as Topic', 'Substance Abuse Detection', 'Substance-Related Disorders', 'United States', 'Young Adult'] | 27,482,999 | [['M01.060.116'], ['F01.145.317.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.727'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['E05.885', 'N06.850.780.500.765'], ['C25.775', 'F03.900'], ['Z01.107.567.875'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4. | Epiregulin is a member of the epidermal growth factor (EGF) family, and has certain characteristics that are different from that of EGF, including mitogenic responses and binding to EGF receptor (EGFR). Epiregulin may also have another cell surface receptor and/or induces different receptor heterodimerizations for intr... | ['3T3 Cells', 'Animals', 'Breast Neoplasms', 'Epidermal Growth Factor', 'Epiregulin', 'ErbB Receptors', 'Humans', 'Iodine Radioisotopes', 'Mice', 'Mice, Inbred BALB C', 'Phosphorylation', 'Protein Binding', 'Proto-Oncogene Proteins', 'Receptor, ErbB-2', 'Receptor, ErbB-3', 'Receptor, ErbB-4', 'Signal Transduction', 'Tu... | 9,419,975 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D12.644.276.382.562', 'D12.776.467.382.562', 'D23.529.382.562'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.5... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Results and perspectives of the treatment of skeletal neoplasms. | Improvements in the therapy of skeletal neoplasms at the end of the 20th century are the reason for a retrospective view on the development of the therapy of skeletal neoplasms, especially in the Slovak Republic. Up to the sixties years of the 20th century was amputation the imperative in the surgical treatment of mali... | ['Bone Neoplasms', 'Humans', 'Slovakia'] | 12,583,509 | [['C04.588.149', 'C05.116.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.797']] | ['Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Oxidative stress and tumor necrosis factor-alpha-induced alterations in metaphase II mouse oocyte spindle structure. | OBJECTIVE(S): To examine the effect of exogenous exposure to hydrogen peroxide (H(2)O(2)) and tumor necrosis factor (TNF)-alpha on mouse metaphase II (MII) oocyte spindle structure and to examine the potential benefits of supplementing the culture media with vitamin C.DESIGN: Prospective study.SETTING: Research laborat... | ['Animals', 'Female', 'Hydrogen Peroxide', 'Metaphase', 'Mice', 'Oocytes', 'Oxidative Stress', 'Prospective Studies', 'Spindle Apparatus', 'Tumor Necrosis Factor-alpha'] | 17,601,599 | [['B01.050'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G04.144.220.220.687.625', 'G04.144.220.220.781.625', 'G05.113.220.687.625', 'G05.113.220.781.625'], ['B01.050.150.900.649.313.992.635.505.500'], ['A05.360.490.690.680', 'A11.497.497.600'], ['G03.673', 'G07.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro evaluation of protein degradability in the rumen and digestibility of undegraded protein. | A three-phase laboratory procedure suitable for predicting protein degradability in the rumen and digestibility of undegraded protein is reported. In the first phase the feed was incubated with starch and buffered rumen fluid. In the incubation mixture the viability of protease-active bacteria was checked by anaerobic ... | ['Animal Feed', 'Animals', 'Bacteria', 'Dietary Proteins', 'Digestion', 'Male', 'Rumen', 'Ruminants', 'Sheep'] | 2,626,994 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B03'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.250', 'G10.261.190'], ['A13.869.804'], ['B01.050.150.900.649.313.500.380'], ['B01.050.150.900.649.313.500.380.791']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Glycopeptide tolerance in Staphylococcus aureus. | Treatment failures with vancomycin prompted us to investigate the phenomenon of tolerance to glycopeptides in recent clinical isolates of Staphylococcus aureus. We used both MBC/MIC determinations and time-kill measurements to study tolerance to vancomycin and teicoplanin in 35 blood or heart valve isolates of S. aureu... | ['Anti-Bacterial Agents', 'Bacteriophage Typing', 'Colony Count, Microbial', 'Drug Resistance, Microbial', 'Endocarditis, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Staphylococcus aureus', 'Teicoplanin', 'Vancomycin'] | 9,738,836 | [['D27.505.954.122.085'], ['E01.370.225.875.150.125.150', 'E05.200.875.150.125.150'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G06.225', 'G07.690.773.984.269'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.87... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone and joint infections caused by gram-positive bacteria: treatment with cefotaxime. | Cefotaxime treatment was evaluated in 41 patients with serious bone and joint infections. Septic arthritis and bursitis (8), acute and chronic osteomyelitis (33) were treated with 3 to 12 g of cefotaxime per day for three to 52 days. The diagnosis of osteomyelitis or septic arthritis was made on the basis of clinical a... | ['Adolescent', 'Adult', 'Aged', 'Arthritis, Infectious', 'Bacterial Infections', 'Cefotaxime', 'Female', 'Gram-Positive Bacteria', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Neutropenia', 'Osteomyelitis'] | 4,055,056 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C01.100', 'C05.550.114.099'], ['C01.150.252'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['B03.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'],... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Controlled self-assembly and photovoltaic characteristics of porphyrin derivatives on a silicon surface at solid-liquid interfaces. | Two meso-tetraphenylporphyrin (H2TPP) derivatives with different central metal ions, namely ZnTPP, CuTPP, were synthesized, and characterized by a series of spectroscopic methods. Their self-assembly behaviors in mixed solvents without surfactant were systematically investigated. The morphology of the thus produced nan... | ['Electronics', 'Metals', 'Nanostructures', 'Particle Size', 'Porphyrins', 'Silicon', 'Solar Energy', 'Solvents', 'Surface Properties'] | 24,647,426 | [['H01.671.293'], ['D01.552'], ['J01.637.512'], ['G02.712'], ['D03.383.129.578.840.500', 'D03.633.400.909.500', 'D04.345.783.500', 'D23.767.727'], ['D01.268.513.937'], ['G01.750.897', 'N06.230.132.644.500'], ['D27.720.844'], ['G02.860']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Some anatomical and mechanical considerations relevant to the surface replacement of the femoral head. | The internal structure of the arthrosic and normal femoral heads are grossly different although both are roughly circular. In particular bone is destroyed or defective superolaterally in the former. The compressive strength of the femoral head depends upon the medial trabecular system which runs through the head at app... | ['Biomechanical Phenomena', 'Femur Head', 'Humans', 'Joint Prosthesis', 'Osteoarthritis', 'Prosthesis Design'] | 729,243 | [['G01.154.090', 'G01.374.089'], ['A02.835.232.043.150.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400'], ['C05.550.114.606', 'C05.799.613'], ['E05.320.550', 'E07.695.680']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence for an optimal level of connectivity for establishment and colonization. | Dispersal is usually associated with the spread of invasive species, but it also has two opposing effects, one decreasing and the other increasing the probability of establishment. Indeed, dispersal both slows population growth at the site of introduction and increases the likelihood of surrounding habitat being coloni... | ['Animal Distribution', 'Animals', 'Ecosystem', 'Introduced Species', 'Models, Biological', 'Wasps'] | 27,903,780 | [['F01.145.113.069', 'G16.049'], ['B01.050'], ['G16.500.275.157', 'N06.230.124'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['E05.599.395'], ['B01.050.500.131.617.720.500.500.875.900']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Thermomechanical Fractional Model of TEMHD Rotational Flow. | In this work, the fractional mathematical model of an unsteady rotational flow of Xanthan gum (XG) between two cylinders in the presence of a transverse magnetic field has been studied. This model consists of two fractional parameters á and â representing thermomechanical effects. The Laplace transform is used to obtai... | ['Biomechanical Phenomena', 'Engineering', 'Fourier Analysis', 'Hot Temperature', 'Industry', 'Magnetic Fields', 'Models, Theoretical', 'Polysaccharides, Bacterial', 'Rheology', 'Rotation', 'Solutions'] | 28,045,941 | [['G01.154.090', 'G01.374.089'], ['J01.293'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['J01.576'], ['G01.358.750'], ['E05.599'], ['D09.698.718', 'D23.050.161.616'], ['E05.830', 'H0... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Renal cell carcinoma co-existent with other renal disease: clinico-pathological features in pre-dialysis patients and those receiving dialysis or renal transplantation. | BACKGROUND: Patients on chronic dialysis are prone to developing acquired cystic kidney disease (ACKD), which may lead to the development of renal cell carcinoma (RCC). The risk factors for the development of RCC so far have not been determined in pre-dialysis patients with co-existent renal disease. The aim of this st... | ['Aged', 'Carcinoma, Renal Cell', 'Comorbidity', 'Female', 'Humans', 'Kidney Diseases, Cystic', 'Kidney Neoplasms', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Prognosis', 'Renal Dialysis', 'Risk Factors', 'Time Factors'] | 15,316,098 | [['M01.060.116.100'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.403', 'C13.351.968.419.403'], ['C04.588... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Three-dimensional mechano-electrochemical model for smooth muscle contraction of the urinary bladder. | The urinary bladder is a central organ of vertebrates and imposes, based on its extreme deformation (volume changes up to several 100%), special requirements on the overall bladder tissue. However, studies focusing on three-dimensional modelling of bladder deformation and bladder function during micturition are rare. B... | ['Animals', 'Elastin', 'Models, Biological', 'Muscle Contraction', 'Muscle, Smooth', 'Myocytes, Smooth Muscle', 'Swine', 'Urinary Bladder'] | 28,711,025 | [['B01.050'], ['D05.750.078.421', 'D12.776.860.300.350'], ['E05.599.395'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['A11.620.520'], ['B01.050.150.900.649.313.500.880'], ['A05.810.890']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Patients of an ambulatory sleep center--critical variables of insomniacs]. | The following study presents results of a broad diagnostical screening for 128 insomniacs, which includes polysomnography, sleep-wake diaries and psychosometrical testing. It was our special aim to investigate about critical but not classical variables for insomnia, which had been mentioned in sleep literature before. ... | ['Adult', 'Aged', 'Ambulatory Care', 'Circadian Rhythm', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Middle Aged', 'Polysomnography', 'Psychophysiology', 'Reference Values', 'Sleep Initiation and Maintenance Disorders', 'Sleep Stages'] | 8,588,375 | [['M01.060.116'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['M01.060.116.630'], ['E01.370.520.625'], ['E02.190.525.812', 'F02.830', 'F04.096.795', 'H01.158.782.795'], ['E05.978.810']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Antioxidant and anti-fatigue effects of anthocyanins of mulberry juice purification (MJP) and mulberry marc purification (MMP) from different varieties mulberry fruit in China. | Anthocyanins, copiously distributed in a variety of colored fruits and vegetables, are probably the most important group of visible plant pigments besides chlorophyll. And the mulberry fruit is one of the anthocyanins-rich fruits. Total flavonols, total phenolic acids and anthocyanins contents of ten varieties mulberry... | ['Animals', 'Anthocyanins', 'Antioxidants', 'Beverages', 'Energy Drinks', 'Exercise Tolerance', 'Fatigue', 'Flavonols', 'Food-Processing Industry', 'Free Radical Scavengers', 'Fruit', 'Glucosides', 'Industrial Waste', 'Mice', 'Morus', 'Phenols', 'Plant Extracts', 'Random Allocation', 'Swimming'] | 23,727,333 | [['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.100', 'J02.200'], ['G07.203.100.512', 'J02.200.512'], ['G11.427.680.270'], ['C23.888.369'], ['D03.383.663.283.266.450.284', 'D03.633.100.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
[The laparoscopic approach to cholecysto-choledocholithiasis.The "rendez-vous " technique]. | A combined method of endoscopic sphincterotomy (ES) with common bile duct (CBD) stone extraction and laparoscopic cholecystectomy under general anesthesia for a single-session treatment of patients with colecysto-choledocholithiasis is described. The so called "rendez-vous" technique consists in: standard laparoscopic ... | ['Cholecystectomy, Laparoscopic', 'Choledocholithiasis', 'Cholelithiasis', 'Feasibility Studies', 'Humans'] | 14,870,557 | [['E04.210.120.172.140', 'E04.502.250.520.160'], ['C06.130.120.250.174', 'C06.130.409.267'], ['C06.130.409'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of new IL28B genotyping method using Invader Plus assay. | IL28B polymorphism is associated with the response to pegylated interferon-á with ribavirin (PEG-IFN-á/RBV) treatment in chronic hepatitis C patients. As a genotyping assay for IL28B single nucleotide polymorphisms (SNPs) in clinical practice, the Invader Plus assay was developed. The accuracy, intra-assay, inter-assay... | ['Adult', 'Aged', 'Asian Continental Ancestry Group', 'Female', 'Genetic Techniques', 'Genotype', 'Hepatitis C, Chronic', 'Humans', 'Interferon-alpha', 'Interferons', 'Interleukins', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Reagent Kits, Diagnostic', 'Ribavirin'] | 22,537,149 | [['M01.060.116'], ['M01.060.116.100'], ['M01.686.508.200'], ['E05.393'], ['G05.380'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Obstructive jaundice caused by primary choledochal hydatid cyst mimicking radiologically choledochal cyst. | A 12-year-old girl with obstructive jaundice that was initially misinterpreted radiologically as having choledochal cyst is presented. A primary hydatid cyst in the wall of the common bile duct causing obstruction was found at operation. The authors emphasize that hydatid cyst should be included in the list of differen... | ['Anastomosis, Roux-en-Y', 'Child', 'Cholangiography', 'Cholecystectomy', 'Cholecystography', 'Choledochal Cyst', 'Cholestasis, Extrahepatic', 'Common Bile Duct', 'Diagnosis, Differential', 'Echinococcosis, Hepatic', 'Female', 'Humans', 'Jaundice, Obstructive', 'Jejunum', 'Liver', 'Suction'] | 12,596,118 | [['E04.035.070', 'E04.210.070'], ['M01.060.406'], ['E01.370.350.700.715.200', 'E01.370.372.200'], ['E04.210.120.172'], ['E01.370.350.700.715.210', 'E01.370.372.210'], ['C04.182.198', 'C06.130.120.127', 'C06.198.184', 'C16.131.314.184'], ['C06.130.120.135.150'], ['A03.159.183.079.300'], ['E01.171'], ['C01.610.335.190.39... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Neural Basis for Contagious Yawning. | Contagious yawning, in which yawning is triggered involuntarily when we observe another person yawn, is a common form of echophenomena-the automatic imitation of another's words (echolalia) or actions (echopraxia) [1]. The neural basis for echophenomena is unknown; however, it has been proposed that it is linked to dis... | ['Adult', 'Humans', 'Imitative Behavior', 'Transcranial Magnetic Stimulation', 'Yawning', 'Young Adult'] | 28,867,202 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.510'], ['E02.621.820'], ['G09.772.982'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunologic and biochemical properties of the major mouse urinary allergen (Mus m 1). | Rabbit antiserum to the mouse major urinary protein identified a single antigen that was also found in mouse serum and pelt extract. The skin test reactivity of mouse-pelt extract and mouse urine in two mouse-allergic subjects was significantly reduced after immunoabsorption with the gamma globulin fraction of this ant... | ['Allergens', 'Animals', 'Antibodies', 'Female', 'Humans', 'Hypersensitivity', 'Immunodiffusion', 'Immunoglobulin E', 'Isoelectric Point', 'Male', 'Mice', 'Molecular Weight', 'Proteins', 'Tissue Distribution'] | 3,097,107 | [['D23.050.063'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['D12.776.124.486.485.114.619.312'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fast and efficient microfluidic cell filter for isolation of circulating tumor cells from unprocessed whole blood of colorectal cancer patients. | Liquid biopsy offers unique opportunities for low invasive diagnosis, real-time patient monitoring and treatment selection. The phenotypic and molecular profile of circulating tumor cells (CTCs) can provide key information about the biology of tumor cells, contributing to personalized therapy. CTC isolation is still ch... | ['Adenomatous Polyposis Coli Protein', 'Aged', 'Cell Line, Tumor', 'Cell Separation', 'Colorectal Neoplasms', 'DNA Mutational Analysis', 'Equipment Design', 'Female', 'Humans', 'Lab-On-A-Chip Devices', 'Liquid Biopsy', 'Male', 'Mutation', 'Neoplastic Cells, Circulating', 'Polymerase Chain Reaction', 'Reference Values',... | 31,142,796 | [['D05.500.117.249', 'D12.776.220.040', 'D12.776.476.081.249', 'D12.776.624.776.010'], ['M01.060.116.100'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CT assessment of the inferior peripancreatic veins: clinical significance. | OBJECTIVE: The purpose of this study was to evaluate and clarify the clinical significance of CT scans of the inferior peripancreatic veins.MATERIALS AND METHODS: Forty-three patients with suspected pancreatic disease underwent three-phase helical CT (collimation, 5 mm; reconstruction, 2.5 mm; scan delay, 30, 60, and 1... | ['Adult', 'Aged', 'Ampulla of Vater', 'Common Bile Duct Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Pancreas', 'Pancreatic Neoplasms', 'Pancreatitis', 'Phlebography', 'Reference Values', 'Tomography, X-Ray Computed', 'Veins'] | 10,701,608 | [['M01.060.116'], ['M01.060.116.100'], ['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['C04.588.274.120.250.250', 'C06.130.120.120.280', 'C06.130.120.250.280', 'C06.130.320.120.280', 'C06.301.120.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Low Expression and Clinical Value of hsa_circ_0049224 and has_circ_0049220 in Systemic Lupus Erythematous Patients. | BACKGROUND The aim of this study was to discuss the possible roles and clinical value of 2 circRNAs (hsa_circ_0049224 and has_circ_0049220) in SLE patients. MATERIAL AND METHODS Reverse-transcription real-time polymerase chain reaction (RT-PCR) was conducted to detect the expressions of hsa_circ_0049224, has_circ_00492... | ['Adult', 'Female', 'Humans', 'Leukocytes, Mononuclear', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'RNA', 'RNA, Circular', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Transcriptome'] | 29,606,700 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['C17.300.480', 'C20.111.590'], ['M01.060.116.630'], ['D13.444.735'], ['D13.444.735.032'], ['D13.444.735.544'], ['E05.393.620.500.706'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prenatal morphine enhances morphine-conditioned place preference in adult rats. | Conditioned place preference (CPP) is a commonly used method for assessing the rewarding qualities of drugs, including opiates. In the present study, we examined long-term effects of prenatal morphine on morphine-associated place preference. Pregnant Fischer 344 rats were given increasing doses of morphine (0.75-12.0 m... | ['Animals', 'Conditioning, Psychological', 'Female', 'Maternal Exposure', 'Morphine', 'Narcotics', 'Opioid-Related Disorders', 'Pregnancy', 'Rats', 'Rats, Inbred F344', 'Reward', 'Task Performance and Analysis'] | 9,300,614 | [['B01.050'], ['F02.463.425.179'], ['N06.850.460.350.145'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.760', 'D27.505.954.427.040.550', 'D27.505.954.427.210.600'], ['C25.775.643.500', 'F03.900.647.500'], ['G0... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The interaction of epidermal growth factor and radiation in human head and neck squamous cell carcinoma cell lines with vastly different radiosensitivities. | PURPOSE: This study was performed to characterize the interaction of epidermal growth factor and radiation in two human head and neck squamous cell cancer cell lines of vastly different radiosensitivities (UM-SCC-6 Radiosensitive; UM-SCC-1 radioresistant).METHODS AND MATERIALS: The two human head and neck squamous cell... | ['Carcinoma, Squamous Cell', 'Cell Cycle', 'Cell Survival', 'Epidermal Growth Factor', 'Head and Neck Neoplasms', 'Humans', 'Radiation Tolerance', 'Tumor Cells, Cultured'] | 8,195,014 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.144'], ['G04.346'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.712', 'G07.738'], ['A11.251.860']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A GIS-based assessment on the vulnerability and future extent of the tropical forests of the Congo Basin. | This paper examines the vulnerability of the Congo Basin's forests through a GIS platform, taking into consideration the variables of population growth, road density, logging concession, and forest fragmentation. The assessment indicates that the forests will continue to shrink towards the interior over the next 50 yea... | ['Africa, Central', 'Conservation of Natural Resources', 'Environmental Monitoring', 'Geographic Information Systems', 'Rivers', 'Trees', 'Tropical Climate', 'Urbanization'] | 16,502,279 | [['Z01.058.290.100'], ['J01.256', 'N06.230.080'], ['N06.850.460.350.080', 'N06.850.780.375'], ['L01.313.500.750.300.314', 'L01.470.750.750.462'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['B01.650.915'], ['G16.500.275.071.600', 'N06.230.300.100.250.600'], ['I01.880.853.400.726']] | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
[Arthrodesis of the metatarsophalangeal joint of the big toe - a report on six years' experience (author's transl)]. | At the orthopedic clinic of L?beck College of Medicine surgical treatment of disorders of the metatarsophalangeal joint of the big toe has, since 1975, included arthrodesis of this joint using a small bone chip. In the light of experience gathered in 150 arthrodeses performed to date, this paper aims to point out major... | ['Arthritis, Rheumatoid', 'Arthrodesis', 'Bone Plates', 'Bone Screws', 'Gout', 'Humans', 'Metatarsophalangeal Joint', 'Postoperative Complications', 'Radiography', 'Toe Joint'] | 7,113,368 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E04.555.100'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['C05.550.114.423', 'C05.550.354.500', 'C05.799.414', 'C16.320.565.798.368', 'C18.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serological evidence of human klassevirus infection. | Klassevirus is a proposed new genus of picornavirus that has been associated with pediatric diarrhea. In this study, we used recombinant klassevirus 3C protease as the capture antigen for an indirect serological enzyme-linked immunosorbent assay (ELISA). Four of six klassevirus reverse transcription (RT)-PCR-positive i... | ['Adolescent', 'Adult', 'Aged', 'Antigens, Viral', 'Child', 'Child, Preschool', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Infant', 'Infant, Newborn', 'Middle Aged', 'Molecular Sequence Data', 'Picornaviridae', 'Picornaviridae Infections', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sequence ... | 20,739,504 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.050.327'], ['M01.060.406'], ['M01.060.406.448'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Noninvasive multimodal evaluation of bioengineered cartilage constructs combining time-resolved fluorescence and ultrasound imaging. | A multimodal diagnostic system that integrates time-resolved fluorescence spectroscopy, fluorescence lifetime imaging microscopy, and ultrasound backscatter microscopy is evaluated here as a potential tool for assessing changes in engineered tissue composition and microstructure nondestructively and noninvasively. The ... | ['Adipose Tissue', 'Animals', 'Bioengineering', 'Cartilage', 'Collagen', 'DNA', 'Elastic Modulus', 'Glycosaminoglycans', 'Horses', 'Imaging, Three-Dimensional', 'Linear Models', 'Mechanical Phenomena', 'Spectrometry, Fluorescence', 'Staining and Labeling', 'Stem Cells', 'Time Factors', 'Tissue Engineering', 'Tissue Sca... | 21,303,258 | [['A10.165.114'], ['B01.050'], ['J01.293.069'], ['A02.165', 'A10.165.382'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D13.444.308'], ['G01.374.590.605'], ['D09.698.373'], ['B01.050.150.900.649.313.984.235.472'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750'... | ['Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
White coated corruption. | This essay documents the state of the medical profession which was once a respected line of work but today is corrupted at every level, from medical education to medical practice, and ir both the private and government sectors. It calls for doctors, thE government and the public to act against dishonest doctors restore... | ['Crime', 'Ethics, Medical', 'Government Regulation', 'Humans', 'India', 'Malpractice', 'Poverty', 'Professional Misconduct', 'Public Policy', 'State Medicine'] | 20,166,290 | [['I01.198.240', 'I01.880.735.191'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['I01.880.604.583.524', 'N03.706.535.606'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['K01.752.566.479.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Morphofunctional changes in the spleen in idiopathic thrombocytopenic purpura]. | Morphofunctional changes in the spleen in this disease were assessed using a number of histological, histoenzymochemical, morphometric, cytological, and immunological methods. The study included 52 operatively removed spleens. Hyperplastic changes in the white pulp varying in different age groups were demonstrated. Irr... | ['Adolescent', 'Adult', 'B-Lymphocytes', 'Histocytochemistry', 'Humans', 'Leukocyte Count', 'Middle Aged', 'Purpura, Thrombocytopenic', 'Rosette Formation', 'Spleen', 'T-Lymphocytes'] | 6,602,606 | [['M01.060.057'], ['M01.060.116'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Mass isolation of highly purified canine islets using an automated method and Histopaque Ficoll gradients. | Eighteen pancreata from adult mongrel dogs were used for the study of islet isolation. The pancreas was distended with collagenase in Hanks' solution. The automated screen method and Histopaque Ficoll gradients were used to isolate and purify the canine islets. In vitro, the viability of isolated islets was assessed by... | ['Animals', 'Automation', 'Cell Separation', 'Centrifugation, Density Gradient', 'Diatrizoate', 'Dogs', 'Equipment Design', 'Female', 'Ficoll', 'Hyperglycemia', 'Hypoglycemia', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Islets of Langerhans Transplantation', 'Male', 'Mice', 'Mice, Nude', 'Pancreas'] | 8,171,165 | [['B01.050'], ['J01.897.104'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.181.724.336', 'E05.196.941.336'], ['D02.241.223.100.400.880.270', 'D02.455.426.559.389.127.375.880.270'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.320'], ['D09.698.330'], ['C18.452.394.952'], ['C18.452.394.984'], [... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Extradural spinal angiolipoma associated with bone lysis in a dog. | An extradural spinal tumor was diagnosed in a 12-year-old Labrador retriever that was presented with a one-week history of paraparesis. Myelography indicated a deviation of the spinal cord to the right side at the level of the second lumbar (L2) vertebra. The difference in length measuring the left and right sides of t... | ['Angiolipoma', 'Animals', 'Dog Diseases', 'Dogs', 'Female', 'Lumbar Vertebrae', 'Myelography', 'Spinal Cord Neoplasms', 'Spondylolysis', 'Tomography, X-Ray Computed'] | 9,728,466 | [['C04.557.450.550.100'], ['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['A02.835.232.834.519'], ['E01.370.350.578.937.505', 'E01.370.350.700.560.505', 'E01.370.376.537.750.505', 'E05.629.937.505'], ['C04.588.614.250.803', 'C10.228.854.765', 'C10.551.240.750'], ['C05.116.900.938.500'], ['E01.37... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats. | Descending noradrenergic inhibition is an important endogenous pain-relief mechanism which can be activated by local glutamate signaling. In the present study, we examined the effect of glutamate transporter activation by riluzole in the regulation of activity of locus coeruleus (LC) neurons, which provide the major in... | ['Amino Acid Transport System X-AG', 'Animals', 'Astrocytes', 'Cells, Cultured', 'Central Nervous System Agents', 'Cyclic AMP Response Element-Binding Protein', 'Dose-Response Relationship, Drug', 'Glutamic Acid', 'In Vitro Techniques', 'Locus Coeruleus', 'Male', 'Neural Inhibition', 'Neural Pathways', 'Neurons', 'Pain... | 20,059,984 | [['D12.776.157.530.200.249.500', 'D12.776.157.530.937.250', 'D12.776.543.585.200.249.500', 'D12.776.543.585.937.250'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['D27.505.954.427'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.125.067.625.349', 'D12.125.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The first fatal case of Mediterranean spotted fever in Croatia. | The first lethal case of Mediterranean spotted fever in Croatia is described. A previously healthy, 58-year-old man was admitted to the hospital with high fever and rash. Several days later, severe anemia, leukopenia and thrombocytopenia developed, and the patient died about eight weeks after the onset of disease. Bone... | ['Boutonneuse Fever', 'Croatia', 'Fatal Outcome', 'Humans', 'Male', 'Middle Aged'] | 11,379,485 | [['C01.150.252.400.789.725.400.250', 'C01.920.930.887.250'], ['Z01.542.248.295'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of inosine on adenosine-induced coronary vasodilation in the open chest dog. | The effects of inosine (CAS 58-63-9) on adenosine-induced coronary vasodilation were studied in open-chest dogs. Inosine and hypoxanthine were infused into the coronary artery at a rate to obtain respective calculated coronary plasma concentrations of 10(-5) mol/l, and the dose-coronary flow response of adenosine was r... | ['Adenosine', 'Adenosine Deaminase', 'Animals', 'Blood Pressure', 'Coronary Circulation', 'Dogs', 'Female', 'Heart', 'Heart Conduction System', 'Heart Rate', 'Hypoxanthines', 'Infusions, Intra-Arterial', 'Inosine', 'Male', 'Myocardium', 'Theophylline', 'Vasodilation'] | 8,240,456 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D08.811.277.151.486.075'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['A07.541.409'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D03.633.100.759.758.399'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The National Rural Health Mission (NRHM): a critical overview. | This paper explores the forces that led to the conceptualisation of the National Rural Health Mission (NRHM) including the role of the Common Minimum Programme and the Structural Adjustment Programme. The paper analyses the key components of the NRHM in terms of the theoretical frameworks of decentralisation, integrati... | ['Humans', 'India', 'National Health Programs', 'Public Health Administration', 'Rural Health Services'] | 16,468,277 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['N03.349.550'], ['N04.452.794'], ['N02.421.816']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Enzyme inhibition by allosteric capture of an inactive conformation. | All members of the human herpesvirus protease (HHV Pr) family are active as weakly associating dimers but inactive as monomers. A small-molecule allosteric inhibitor of Kaposi's sarcoma-associated herpesvirus protease (KSHV Pr) traps the enzyme in an inactive monomeric state where the C-terminal helices are unfolded an... | ['Allosteric Site', 'Binding Sites', 'Catalytic Domain', 'Circular Dichroism', 'Crystallography, X-Ray', 'Dimerization', 'Enzyme Inhibitors', 'Herpesvirus 8, Human', 'Humans', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Mutagenesis', 'Protein Binding', 'Protein Conformation', 'Serine Endopeptidases'] | 21,723,875 | [['G02.111.570.120.147'], ['G02.111.570.120'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.867.151'], ['E05.196.309.742.225'], ['G02.206', 'G03.230'], ['D27.505.519.389'], ['B04.280.210.400.700.330', 'B04.280.382.400.700.330', 'B04.613.204.500.700.330'], ['B01.050.150.900.649.313.988.400.112.4... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association and expression study of synapsin III and schizophrenia. | The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate ... | ['Adult', 'China', 'Female', 'Genetic Linkage', 'Genetic Predisposition to Disease', 'Heterozygote', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Risk Assessment', 'Risk Factors', 'Schizophrenia', 'Synapsins'] | 19,766,700 | [['M01.060.116'], ['Z01.252.474.164'], ['G05.348'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['G05.365.795.598'], ['E05.... | ['Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Dosing regimen of budesonide and occurrence of oropharyngeal complications. | The influence of the dosing regimen on the occurrence of oropharyngeal complications during a trial of the anti-asthmatic aerosol steroid budesonide was assessed by systematically varying the daily dose (400, 800, 1,600 micrograms), dose frequency (b.i.d. vs. q.i.d.), and dosing schedule (AM vs. AM/PM). Dysphonia was i... | ['Aerosols', 'Asthma', 'Budesonide', 'Candidiasis, Oral', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pregnenediones', 'Voice Disorders'] | 6,705,856 | [['D20.280.055', 'D26.255.165.055'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D04.210.500.745.745.654.105'], ['C01.150.703.160.180', 'C07.465.130'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D04.210... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Metal-Free Iodine-Catalyzed Direct Arylthiation of Substituted Anilines with Thiols. | Iodine-catalyzed direct arylthiation of substituted anilines for the synthesis of various diaryl sulfides has been developed under metal- and solvent-free conditions. The present method uses readily available thiols as the arylthiation reagents, and environmentally friendly and inexpensive I2 as the catalyst. Important... | ['Aniline Compounds', 'Catalysis', 'Iodine', 'Ligands', 'Metals', 'Molecular Structure', 'Sulfhydryl Compounds', 'Sulfides'] | 26,030,066 | [['D02.092.146'], ['G02.130'], ['D01.268.380.400'], ['D27.720.470.480'], ['D01.552'], ['G02.111.570', 'G02.466'], ['D02.886.489'], ['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the immunophenotypes of signet-ring cell carcinoma, solid adenocarcinoma with mucin production, and mucinous bronchioloalveolar carcinoma of the lung characterized by the presence of cytoplasmic mucin. | The latest World Health Organization (WHO) classification divides adenocarcinoma mainly into adenocarcinoma mixed subtypes, acinar adenocarcinoma, papillary adenocarcinoma, bronchioloalveolar carcinoma, and solid adenocarcinoma with mucin production, and it mentions several variants, including fetal adenocarcinoma, muc... | ['Adenocarcinoma', 'Adenocarcinoma, Bronchiolo-Alveolar', 'Adenocarcinoma, Mucinous', 'Carcinoma, Signet Ring Cell', 'Humans', 'Immunoenzyme Techniques', 'Immunophenotyping', 'Lung Neoplasms', 'Mucins', 'Neoplasm Proteins', 'Protein Array Analysis'] | 16,463,270 | [['C04.557.470.200.025'], ['C04.557.470.200.025.022.500', 'C04.588.894.797.520.055.500'], ['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E01.370.225.812.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Survival of patients on maintenance haemodialysis over a twenty-year period. | Patient survival is a key index of the overall adequacy of treatment in most chronic diseases. Analyses of survival of patients undergoing haemodialysis is very important, as it may offer clues and ideas for prolonging survival of patients with end-stage renal disease (ESRD). The aims of this study were to describe the... | ['Adult', 'Aged', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Survival Analysis', 'Survival Rate'] | 18,356,782 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E02.870.300', 'E02.912.800'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', '... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biological and Clinical Relevance of Long Non-Coding RNA PCAT-1 in Cancer, A Systematic Review and Meta-Analysis | Long non-coding RNA (lncRNA) prostate cancer associated transcript 1 (PCAT-1) has been identified as a potential
biomarker for the diagnosis and prognosis of various cancers. We performed this systematic review and meta-analysis
to evaluate the role of dysregulation as well as the biological and clinical significance o... | ['Biomarkers, Tumor', 'Humans', 'Neoplasms', 'Prognosis', 'RNA, Long Noncoding'] | 30,909,662 | [['D23.101.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E01.789'], ['D13.444.735.790.375']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure of sirohydrochlorin ferrochelatase SirB: the last of the structures of the class II chelatase family. | The crystal structure of Bacillus subtilis SirB, which catalyses the insertion of Fe2+ into the substrate sirohydrochlorin (SHC) in siroheme biosynthesis, is reported herein as the last of the structures of class II chelatases. The structure of SirB with Co2+ showed that the active site of SirB is located at the N-term... | ['Amino Acids', 'Bacillus subtilis', 'Bacterial Proteins', 'Biosynthetic Pathways', 'Catalytic Domain', 'Cobalt', 'Crystallization', 'Ferrochelatase', 'Hydrophobic and Hydrophilic Interactions', 'Molecular Docking Simulation', 'Protein Binding', 'Protein Conformation', 'Tetrapyrroles', 'Uroporphyrins'] | 30,778,451 | [['D12.125'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['G02.111.098', 'G03.493.100'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Diffuse Alveolar Septal Amyloidosis With Wild-Type Transthyretin With Spontaneous Lung Hematoma. | We experienced a mass formation in the right lower lobe in a patient with cardiac amyloidosis and heart failure. Radiologic findings of the chest showed no abnormality except a mass. The patient had non-valvular atrial fibrillation and was taking edoxaban. Surgical resection of the mass revealed a hematoma. Further pat... | ['Aged', 'Amyloid', 'Amyloid Neuropathies, Familial', 'Atrial Fibrillation', 'Heart Failure', 'Hematoma', 'Humans', 'Lung Diseases', 'Male', 'Prealbumin', 'Pulmonary Alveoli'] | 30,009,808 | [['M01.060.116.100'], ['D05.500.049', 'D12.776.049'], ['C10.574.500.050', 'C10.668.829.050.050', 'C16.320.400.050', 'C16.320.565.176.050', 'C18.452.648.176.050', 'C18.452.845.500.050.050', 'C18.452.845.500.075.050'], ['C14.280.067.198', 'C23.550.073.198'], ['C14.280.434'], ['C23.550.414.838'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The inhibition of keratoplasty rejection with topical cyclosporin A]. | 23 postoperative patients of keratoplasty were instilled 1% cyclosporin A eyedrops in addition to routine systemic corticosteroids, with reduced rate of rejection and increased rate of transparency of the corneal grafts. The values of OKT3, OKT4/OKT8 ratio, and Et-RFC were also reduced in comparison with those of the c... | ['Adolescent', 'Adult', 'CD4-CD8 Ratio', 'Child', 'Cyclosporine', 'Graft Rejection', 'Humans', 'Keratoplasty, Penetrating', 'Middle Aged', 'Ophthalmic Solutions'] | 1,818,823 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E05.242.195.107.595.500.150.160', 'G04.140.107.595.500.150.160', 'G09.188.105.595.500.150.160', 'G12.248'], ['M01.060.406'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Aortic Valve Replacement after Balloon Valvuloplasty for Aortic Valve Stenosis in a Dialysis Patient with Cardiogenic Shock;Report of a Case]. | A 67-year-old man on chronic hemodialysis was admitted with worsening congestive heart failure due to critical aortic stenosis. Echocardiography showed severe aortic stenosis with a valve area of 0.67 cm2 and an ejection fraction of 0.31. Cardiac catheterization revealed severe pulmonary hypertension with pulmonary art... | ['Aged', 'Aortic Valve', 'Aortic Valve Stenosis', 'Balloon Valvuloplasty', 'Cardiac Catheterization', 'Humans', 'Male', 'Renal Dialysis', 'Shock, Cardiogenic'] | 26,066,880 | [['M01.060.116.100'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E02.148.108', 'E05.157.125'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.300', 'E02.912.800'], ['C14.280.647.500.750', 'C14.907.585.500.750', 'C23.550.513.355.7... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A multicenter phase II study of combined chemotherapy with docetaxel, cisplatin, and S-1 in patients with unresectable or recurrent gastric cancer (KDOG 0601). | PURPOSE: We conducted a phase II study to evaluate the efficacy and safety of a triplet regimen of docetaxel, cisplatin, and S-1 in patients with unresectable or recurrent gastric cancer.METHODS: Docetaxel (40 mg/m(2)) and cisplatin (70 or 60 mg/m(2)) were given on day 1 of a 28-day cycle. S-1 (40 mg/m(2)) was given tw... | ['Adult', 'Aged', 'Anemia', 'Antineoplastic Combined Chemotherapy Protocols', 'Cisplatin', 'Docetaxel', 'Drug Administration Schedule', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Leukopenia', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neutropenia', 'Oxonic Acid', 'Stomach Neoplasms', 'Taxoids', 'Tegafur',... | 21,796,483 | [['M01.060.116'], ['M01.060.116.100'], ['C15.378.071'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hfr mapping of mutations in Bordetella pertussis that define a genetic locus involved in virulence gene regulation. | We report the development of techniques for the genetic mapping of point mutations in the bacterial pathogen Bordetella pertussis. A plasmid vector which is self-transmissible by conjugation and which, by insertion into the B. pertussis chromosome, can mobilize chromosomal sequences during conjugation with a recipient ... | ['Adenylate Cyclase Toxin', 'Bacterial Proteins', 'Base Sequence', 'Bordetella pertussis', 'Chromosome Mapping', 'Chromosomes, Bacterial', 'Conjugation, Genetic', 'Crosses, Genetic', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Molecular Sequence Data', 'Pertussis Toxin', 'Plasmids', 'Point Mutation', ... | 7,961,497 | [['D08.811.520.650.200.040', 'D23.946.123.946.040', 'D23.946.896.980.040'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.400.425.115.425.600', 'B03.660.075.090.344.425.600'], ['E05.393.183'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['G05.728.200'], ['E05.393.281'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Glycogen synthase kinase 3â promotes osteogenic differentiation of murine adipose-derived stromal cells. | Although the role of glycogen synthase kinase 3â (GSK3â) in osteogenic differentiation of bone marrow-derived mesenchymal stromal cells (BMSCs) is well-characterized as a negative regulator of â-catenin, its effect on osteogenesis of adipose-derived stromal cells (ADSCs) is poorly understood. Here, we show that GSK3â p... | ['Adipocytes', 'Animals', 'Blotting, Western', 'Cell Line', 'Glycogen Synthase Kinase 3', 'Glycogen Synthase Kinase 3 beta', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Osteogenesis', 'Reverse Transcriptase Polymerase Chain Reaction', 'Stromal Cells'] | 23,342,170 | [['A11.329.114'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.500', 'D08.811.913.696.620.682.700.646.625', 'D12.644.360.300.500', 'D12.776.476.081.875', 'D12.776.476.300.500'], ['D... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines. | BACKGROUND: We prepared a novel series of enantiopure mefloquine analogues with pyrrolo[ 1,2-a]quinoxaline core in order to fight Plasmodium falciparum resistant strain.OBJECTIVES: To observe the influence of pyrrolo[1,2-a]quinoxaline core versus quinoline core on the antimalarial activity.METHOD: Four enantiopure amin... | ['Amino Alcohols', 'Animals', 'Antimalarials', 'CHO Cells', 'Cell Line, Tumor', 'Chloroquine', 'Cricetulus', 'Humans', 'Mefloquine', 'Plasmodium falciparum', 'Pyrroles', 'Quinoxalines', 'Stereoisomerism'] | 28,745,231 | [['D02.033.100', 'D02.092.063'], ['B01.050'], ['D27.505.954.122.250.100.085'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.633.100.810.050.180'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.810.410'], ['B01.043.075... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conformational analysis of a 4-hydroxyequilenin Guanine adduct using density functional theory. | Equilenin, a component of the drug Premarin (Wyeth), can be metabolized to a quinonoid, 4-hydroxyequilenin (4-OHEN). 4-OHEN can react with 2'-deoxynucleosides to form unusual cyclic adducts, among which 4-hydroxyequilenin-2'-deoxyguanosine (4-OHEN-dG) is the major product under physiological conditions. The structure a... | ['Equilenin', 'Guanine', 'Models, Molecular', 'Molecular Conformation', 'Stereoisomerism'] | 12,018,985 | [['D04.210.500.365.415.215', 'D04.210.500.578.502.470', 'D06.472.334.851.437.249'], ['D03.633.100.759.758.399.454'], ['E05.599.595'], ['G02.111.570.820'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inducible myocardial ischemia and outcomes in patients with coronary artery disease and left ventricular dysfunction. | OBJECTIVES: The study objectives were to test the hypotheses that ischemia during stress testing has prognostic value and identifies those patients with coronary artery disease (CAD) with left ventricular (LV) dysfunction who derive the greatest benefit from coronary artery bypass grafting (CABG) compared with medical ... | ['Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Echocardiography, Stress', 'Female', 'Fibrinolytic Agents', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Prognosis', 'Prospective Studies', 'Severity of Illness Index', 'Stroke Volume', 'Thrombolytic Therapy'... | 23,500,234 | [['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.350.130.750.228', 'E01.370.350.850.220.228', 'E01.370.370.380.220.228... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acute exacerbation of bronchial asthma in children associated with afternoon weather changes. | We studied the effect of the weather on acute exacerbations of bronchial asthma in children by comparing records of 8,657 admissions for five acute respiratory diseases (3,064 for asthma) with concurrent meteorologic data. These diseases were classified according to their interrelations and distinct meteorologic patter... | ['Acute Disease', 'Adolescent', 'Asthma', 'Bronchiolitis', 'Child', 'Child, Preschool', 'Hospitalization', 'Humans', 'Humidity', 'Laryngitis', 'Meteorological Concepts', 'Pneumonia', 'Respiratory Tract Infections', 'Temperature'] | 2,064,137 | [['C23.550.291.125'], ['M01.060.057'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C01.748.099.135', 'C08.127.446.135', 'C08.381.495.146.135', 'C08.730.099.135'], ['M01.060.406'], ['M01.060.406.448'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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