Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The repeatability of tear mucus ferning grading. | PURPOSE: Rolando's classification system for tear mucus ferning patterns subjectively assigns grades based on the size and spacing between ferns. Grade 1 and 2 patterns are considered "normal," whereas grade 3 and 4 patterns are often associated with keratoconjunctivitis sicca. This study was designed to examine the in... | ['Adolescent', 'Adult', 'Aged', 'Classification', 'Crystallization', 'Female', 'Humans', 'Keratoconjunctivitis Sicca', 'Male', 'Middle Aged', 'Mucus', 'Observer Variation', 'Reproducibility of Results', 'Tears'] | 9,734,804 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['L01.100', 'L01.453.245.275'], ['E05.196.300', 'G02.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.187.183.394.500', 'C11.204.564.585.630', 'C11.496.260.394'], ['M01.060.116.630'], ['A12.200.503'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.15... | ['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Resistance of wild birds to infection by Chlamydia psittaci of mammalian origin. | Numerous species of birds are natural hosts of C. psittaci and have been implicated as sources of certain strains that cause disease in other vertebrate species, notably those producing psittacosis or ornithosis in humans [1]. Although direct evidence of their involvement in the transmission of chlamydiae to other mamm... | ['Animals', 'Bird Diseases', 'Birds', 'Disease Vectors', 'Immunity, Innate', 'Psittacosis'] | 6,822,754 | [['B01.050'], ['C22.131'], ['B01.050.150.900.248'], ['N06.850.335.188', 'N06.850.520.203.375'], ['G12.450.564'], ['C01.150.252.400.210.250.600']] | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Kinetic characterization of the nitric oxide toxicity for PC12 cells: effect of half-life time of NO release. | We investigated the effects of low concentrations of nitric oxide (NO) on cell viability using NO donors, (+/-)-(E)-4-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hex enamid e (NOR1), (+/-)-(E)-4-methyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (NOR2), (+/-)-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (NOR... | ['Animals', 'Antioxidants', 'Ascorbic Acid', 'Cell Survival', 'Cyclic GMP', 'Cysteine', 'DNA', 'DNA Fragmentation', 'Dibutyryl Cyclic GMP', 'Dose-Response Relationship, Drug', 'Glutathione', 'Half-Life', 'Kinetics', 'Nitric Oxide', 'Nitro Compounds', 'Oxadiazoles', 'PC12 Cells', 'Quinoxalines', 'Rats', 'Time Factors'] | 10,844,095 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['G04.346'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.16... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tort reform: an issue for nurse practitioners. | PURPOSE: To inform nurse practitioners (NPs) about the issues related to tort reform and its relationship to malpractice insurance costs.DATA SOURCES: Current journals, newspapers, professional newsletters, and Internet sites.CONCLUSIONS: NPs are paying more for their malpractice premiums, and many are losing their pla... | ['Federal Government', 'Fees and Charges', 'Health Care Reform', 'Humans', 'Insurance, Liability', 'Liability, Legal', 'Malpractice', 'Medical Errors', 'Nurse Practitioners', 'State Government', 'United States'] | 15,055,424 | [['I01.409.137', 'I01.409.418.625', 'N03.540.348.500', 'N03.540.400.750'], ['N03.219.442'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.443'], ['I01.880.604.583.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Loss of DNA mismatch repair imparts a selective advantage in planarian adult stem cells. | Lynch syndrome (LS) leads to an increased risk of early-onset colorectal and other types of cancer and is caused by germline mutations in DNA mismatch repair (MMR) genes. Loss of MMR function results in a mutator phenotype that likely underlies its role in tumorigenesis. However, loss of MMR also results in the elimina... | ['Adult Stem Cells', 'Alkylating Agents', 'Amino Acid Sequence', 'Animals', 'DNA Damage', 'DNA Mismatch Repair', 'DNA-Binding Proteins', 'Evolution, Molecular', 'Humans', 'Mice', 'Mitosis', 'Molecular Sequence Data', 'Planarians', 'RNA Interference', 'Regeneration', 'Selection, Genetic', 'Sequence Homology, Nucleic Aci... | 21,747,960 | [['A11.872.040'], ['D27.505.519.124', 'D27.888.569.035'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G05.200'], ['G02.111.222.220', 'G05.219.220'], ['D12.776.260'], ['G05.045.250', 'G16.075.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G04.144.220... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evidence for a nitrate-independent function of the nitrate sensor NRT1.1 in Arabidopsis thaliana. | NRT1.1 is a putative nitrate sensor and is involved in many nitrate-dependent responses. On the other hand, a nitrate-independent function of NRT1.1 has been implied, but the clear-cut evidence is unknown. We found that NRT1.1 mutants showed enhanced tolerance to concentrated ammonium as sole N source in Arabidopsis th... | ['Anion Transport Proteins', 'Arabidopsis', 'Gene Expression Regulation, Plant', 'Glucosinolates', 'Hydrogen-Ion Concentration', 'Mutation', 'Nitrates', 'Plant Proteins', 'Plant Roots', 'Plant Shoots', 'Quaternary Ammonium Compounds'] | 21,052,766 | [['D12.776.157.530.450.074', 'D12.776.543.585.450.074'], ['B01.650.940.800.575.912.250.157.100'], ['G05.308.375'], ['D02.886.740.703.350', 'D09.408.348.820.350', 'D09.408.903.703.350'], ['G02.300'], ['G05.365.590'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D12.776.765'], ['A18.400'], ['A18.024.875'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selection of plant growth-promoting Pseudomonas spp. that enhanced productivity of soybean-wheat cropping system in Central India. | The aim of this investigation was to select effective Pseudomonas sp. strains that can enhance the productivity of soybean-wheat cropping systems in Vertisols of Central India. Out of 13 strains of Pseudomonas species tested in vitro, only five strains displayed plant growth-promoting (PGP) properties. All the strains ... | ['Cluster Analysis', 'Enzymes', 'Genetic Variation', 'India', 'Pseudomonas', 'Soybeans', 'Triticum'] | 22,127,123 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D08.811'], ['G05.365'], ['Z01.252.245.393'], ['B03.440.400.425.625.625', 'B03.660.250.580.590'], ['B01.650.940.800.575.912.250.401.750'], ['B01.650.940.800.575.912.250.822.918']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging. | Measurement of hemodynamic wall shear stress (WSS) is important in investigating the role of WSS in the initiation and progression of atherosclerosis. Echo particle image velocimetry (echo PIV) is a novel ultrasound-based technique for measuring WSS in vivo that has previously been validated in vitro using the standard... | ['Blood Flow Velocity', 'Carotid Arteries', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Rheology', 'Ultrasonography'] | 28,501,327 | [['E01.370.370.130', 'G09.330.380.630.080'], ['A07.015.114.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.830', 'H01.671.808'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
[Comorbidities and functional impairments in children with attention deficit hyperactivity disorder]. | OBJECTIVE: To assess comorbidities and functional impairments in children with attention deficit hyperactivity disorder (ADHD), and to investigate their relationship with the core symptoms (attention deficit and hyperactivity) of ADHD.METHODS: A total of 319 children with suspected ADHD were included in the study. The ... | ['Adolescent', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child, Preschool', 'Comorbidity', 'Female', 'Humans', 'Male'] | 24,034,913 | [['M01.060.057'], ['F03.625.094.150'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Automated selection of stabilizing mutations in designed and natural proteins. | The ability to engineer novel protein folds, conformations, and enzymatic activities offers enormous potential for the development of new protein therapeutics and biocatalysts. However, many de novo and redesigned proteins exhibit poor hydrophobic packing in their predicted structures, leading to instability or insolub... | ['Automation', 'Biocatalysis', 'Models, Molecular', 'Mutation', 'Proteins'] | 22,307,603 | [['J01.897.104'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['E05.599.595'], ['G05.365.590'], ['D12.776']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The medical specialist for insurance medicine--the Flemish residency]. | Insurance medicine is becoming more and more important. Currently, there are few countries in Europe where insurance medicine is recognised as an independent discipline; the Netherlands is one example. Since 2007 the "Specialist in Insurance Medicine and Medico-legal Expertise" is recognised in Belgium. This article wi... | ['Curriculum', 'Insurance, Health', 'Internship and Residency', 'Medicine', 'Netherlands'] | 22,486,051 | [['I02.158'], ['N03.219.521.576.343'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['H02.403'], ['Z01.542.651']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Incomplete distal renal tubular acidosis from a heterozygous mutation of the V-ATPase B1 subunit. | Congenital distal renal tubular acidosis (RTA) from mutations of the B1 subunit of V-ATPase is considered an autosomal recessive disease. We analyzed a distal RTA kindred with a truncation mutation of B1 (p.Phe468fsX487) previously shown to have failure of assembly into the V1 domain of V-ATPase. All heterozygous carri... | ['Acidosis, Renal Tubular', 'Ammonium Chloride', 'Anion Exchange Protein 1, Erythrocyte', 'Female', 'HEK293 Cells', 'Heterozygote', 'Humans', 'Kidney Medulla', 'Male', 'Mutation', 'Pedigree', 'Saccharomyces cerevisiae', 'Vacuolar Proton-Translocating ATPases'] | 25,164,082 | [['C12.777.419.815.093', 'C13.351.968.419.815.093', 'C16.320.831.093', 'C18.452.076.176.210'], ['D01.210.450.150.050', 'D01.625.062.249'], ['D12.776.157.530.450.162.193.500', 'D12.776.157.530.450.437.249.500', 'D12.776.157.530.937.656.249.500', 'D12.776.543.550.190.276.500', 'D12.776.543.550.779.249.500', 'D12.776.543.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dysplasia epiphysialis multiplex: a case report. | The clinical features of a new patient with dysplasia epiphysialis multiplex are reported. Similar symptoms are present in four members of the family. This disease seems to be inherited as a simple dominant Mendelian trait. The disease mainly affects the epiphyses of the long bone and nearly always begins with pain in ... | ['Adult', 'Biopsy', 'Bone and Bones', 'Female', 'Genes, Dominant', 'Humans', 'Osteochondrodysplasias', 'Osteoporosis', 'Pedigree', 'Radiography'] | 3,731,721 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A02.835.232', 'A10.165.265'], ['G05.360.340.024.340.240', 'G05.420.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.099.708', 'C16.320.728']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods. | Preserving the original RNA orientation information in RNA-Sequencing (RNA-Seq) experiment is essential to the analysis and understanding of the complexity of mammalian transcriptomes. We describe herein a simple, robust, and time-effective protocol for generating strand-specific RNA-seq libraries suited for the Illumi... | ['Deoxyuracil Nucleotides', 'Gene Expression Profiling', 'Gene Library', 'Humans', 'Sequence Analysis, RNA', 'Transcriptome'] | 22,609,201 | [['D03.383.742.686.850.210', 'D13.695.201.200', 'D13.695.740.850.210'], ['E05.393.332'], ['G05.360.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.760.710'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequent EGFR mutations in nonsmall cell lung cancer presenting with miliary intrapulmonary carcinomatosis. | Nonsmall cell lung cancer (NSCLC) presenting with miliary intrapulmonary carcinomatosis (MIPC) is rare. We investigated the clinical characteristics and epidermal growth factor receptor (EGFR) mutation rate of NSCLC patients with MIPC at initial diagnosis. From June 2004 to December 2008, we screened newly diagnosed NS... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma', 'Carcinoma, Non-Small-Cell Lung', 'DNA Mutational Analysis', 'ErbB Receptors', 'Female', 'Gefitinib', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Mutation', 'Quinazolines', 'Radiography, Thoracic', 'Time Factors', 'Treatment Outcome'] | 22,523,351 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.393.760.700.300'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['D03.633.100.786.469'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Case report of flipper anatomic anomaly of Sotalia guianensis from Sepetiba Bay, Rio de Janeiro. | The cetacean flipper consists of a soft tissue that encases most of the forelimb containing humerus, radius, ulna, carpals, metacarpals, and phalanges. Several studies have documented the typical cetacean's flipper anatomy, but only a few described digital anomalies and the most common are fusions and supernumerary suc... | ['Animal Fins', 'Animals', 'Brazil', 'Dolphins', 'Female', 'Forelimb', 'Radius'] | 23,630,189 | [['A13.075'], ['B01.050'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.875.267'], ['A13.395'], ['A02.835.232.087.090.700']] | ['Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Aggressive treatment of acute respiratory insufficiency. | Treatment of patients with severe acute respiratory insufficiency included application of end-expiratory pressure to an optimal level, precise cardiovascular monitoring, and adaptation of conventional respirators to provide intermittent mandatory ventilation. Of 90 patients with acute respiratory insufficiency secondar... | ['Acute Disease', 'Humans', 'Positive-Pressure Respiration', 'Respiration, Artificial', 'Respiratory Insufficiency', 'Ventilators, Mechanical'] | 779,041 | [['C23.550.291.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.625.790', 'E02.880.820.790'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['C08.618.846'], ['E07.950']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of hyporesponsiveness to fully allogeneic cardiac grafts by intratracheal delivery of alloantigen. | BACKGROUND: Soluble protein delivered through the mucosal surface can induce immunological unresponsiveness. The purpose of this study was to determine if prior exposure to alloantigen via the trachea could modulate the immune response to subsequent cardiac allografts.METHODS: Hearts from C57BL/10(H2b) mice were transp... | ['Animals', 'Antibody Formation', 'Graft Survival', 'Heart Transplantation', 'Intubation, Intratracheal', 'Isoantigens', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Inbred CBA'] | 11,258,436 | [['B01.050'], ['G12.450.050.370.250'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['D23.050.705'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thiamine pyrophosphate effect and erythrocyte transketolase activity during severe alcohol withdrawal syndrome. | The thiamine pyrophosphate (TPP) effect and erythrocyte transketolase activity (ETKA) in a group of 28 patients admitted to a psychiatric emergency ward because of severe alcohol withdrawal syndrome were compared with the TPP effect and ETKA in a control group of 20 healthy nonalcoholic volunteers. The patients were tr... | ['Adult', 'Alcohol Withdrawal Delirium', 'Alcoholism', 'Erythrocytes', 'Ethanol', 'Female', 'Humans', 'Injections, Intramuscular', 'Magnesium', 'Male', 'Middle Aged', 'Substance Withdrawal Syndrome', 'Thiamine Deficiency', 'Thiamine Pyrophosphate', 'Transketolase', 'Wernicke Encephalopathy'] | 8,213,210 | [['M01.060.116'], ['C10.720.112.200', 'C25.723.705.150.200', 'C25.775.100.087.193.200', 'C25.775.835.250', 'F03.900.100.100', 'F03.900.825.500'], ['C25.775.100.250', 'F03.900.100.350'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Labdane-type diterpenes from Hedychium gardnerianum with potent cytotoxicity against human small cell lung cancer cells. | Seven labdane-type diterpenes, coronarin E, coronarin A, yunnancoronarin A, yunnancoronarin B, hedyforrestin B, villosin, and hedyforrestin C were isolated from the rhizome of Hedychium gardnerianum and evaluated for cytotoxic activity against human small cell lung cancer (NCI-H187) and non-cancerous Vero cells. The re... | ['4-Butyrolactone', 'Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Chlorocebus aethiops', 'Diterpenes', 'Drug Screening Assays, Antitumor', 'Ellipticines', 'Humans', 'Inhibitory Concentration 50', 'Molecular Structure', 'Plant Roots', 'Vero Cells', 'Zingiberaceae'] | 19,960,422 | [['D02.540.150', 'D03.383.312.150'], ['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D02.455.849.291'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D03.132.436.681.333', 'D03.633.100.473.144.249', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Do therapists address gender and power in infidelity? A feminist analysis of the treatment literature. | Sociocontextual factors such as gender and power play an important role in the etiology of affairs and in recovery from them, yet it is unclear how current treatment models address these issues. Drawing on feminist epistemology, this study utilized a grounded theory analysis of 29 scholarly articles and books on infide... | ['Adult', 'Couples Therapy', 'Extramarital Relations', 'Female', 'Feminism', 'Humans', 'Male', 'Men', 'Power, Psychological', 'Spouses', 'Women'] | 25,059,296 | [['M01.060.116'], ['F04.754.864.581.136'], ['F01.145.802.295'], ['I01.880.604.473.374', 'K01.752.566.479.174.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.390'], ['F01.658.780'], ['F01.829.263.500.660', 'I01.880.853.150.500.670', 'M01.816'], ['M01.975']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit. | Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of glucosidases I and II in the endoplasmic reticulum (ER). We isolated enzymatically active glucosidase II from rat liver and found that, in contrast with previous reports, it contains two subunits... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Conserved Sequence', 'DNA Primers', 'Endoplasmic Reticulum', 'Genes, Fungal', 'Humans', 'Macromolecular Substances', 'Mammals', 'Microsomes, Liver', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Protein Sorting Signals', 'Rats', 'Saccharomyces cerevisiae',... | 8,910,335 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['G02.111.570.580'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A11.284.430.214.190.875.248'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['B01.050.150.900.649.313.988.400.112.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cryoablation for accessory pathways located near normal conduction tissues or within the coronary venous system in children and young adults. | BACKGROUND: Cryoablation may offer advantages over radiofrequency (RF) ablation for certain arrhythmia substrates, such as septal accessory pathways (APs). Data for young patients, especially regarding recurrence risk, require expansion.OBJECTIVES: The purpose of this study was to study institutional outcomes for cryoa... | ['Adolescent', 'Adult', 'Catheter Ablation', 'Child', 'Child, Preschool', 'Coronary Vessels', 'Cryosurgery', 'Electrocardiography', 'Female', 'Heart Conduction System', 'Heart Septum', 'Humans', 'Male', 'Recurrence', 'Tachycardia, Supraventricular', 'Treatment Outcome'] | 16,500,293 | [['M01.060.057'], ['M01.060.116'], ['E02.808.750.500', 'E04.014.760.500'], ['M01.060.406'], ['M01.060.406.448'], ['A07.015.114.269', 'A07.015.908.194'], ['E04.014.180'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.409'], ['A07.541.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.937'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perioperative Outcomes and Safety of Atrial Fibrillation Catheter Ablation in Octogenarians: A Retrospective Study and Review of the Benefits of Rhythm Control. | OBJECTIVES: Catheter ablation for rhythm control has emerged as a successful therapeutic option for the treatment of atrial fibrillation (AF), though it has not been well studied in octogenarians. This study evaluates its safety in octogenarians in a community hospital and reviews the benefits of rhythm control.METHODS... | ['Aged', 'Aged, 80 and over', 'Atrial Fibrillation', 'Catheter Ablation', 'Electrocardiography', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Recurrence', 'Reoperation', 'Retrospective Studies', 'Treatment Outcome'] | 28,427,082 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.71... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enamel matrix derivative (Emdogain) in treatment of replanted teeth - a systematic review. | OBJECTIVE: The main purpose of the present systematic review was to evaluate the efficacy of enamel matrix derivative Emdogain in healing of replanted teeth in humans.MATERIALS AND METHODS: This review conducted in adherence to PRISMA standards and was registered in PROSPERO with registration number CRD42017062736. We ... | ['Dental Enamel Proteins', 'Humans', 'Periodontal Ligament', 'Root Canal Preparation', 'Root Resorption', 'Tooth Avulsion', 'Tooth Replantation', 'Wound Healing'] | 30,422,034 | [['D12.776.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.646.771'], ['E06.397.778.889', 'E06.931.625'], ['C07.793.901.653', 'G10.549.855.653'], ['C07.793.850.725', 'C26.900.725'], ['E04.545.710', 'E04.936.494.711', 'E06.397.898', 'E06.645.710'], ['G16.762.891']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular genetics of anti-carbohydrate antibodies. | Antibodies directed against carbohydrate determinants provide useful model systems for understanding the structure and organisation of antibody genes and the generation of antibody diversity. We have used three such systems, PC, DEX and GAC, and have studied the heavy chains and VH gene segments of each. In two of thes... | ['Animals', 'Antibodies', 'Antibody Diversity', 'Antibody Formation', 'Carbohydrates', 'DNA', 'DNA Restriction Enzymes', 'Deoxyribonuclease EcoRI', 'Dextrans', 'Mice', 'Mice, Inbred BALB C', 'Phosphorylcholine', 'Polysaccharides, Bacterial'] | 6,201,131 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G05.365.036', 'G12.500.199'], ['G12.450.050.370.250'], ['D09'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D08.811.150.280.260.300', 'D08.811.277.352.335.350.300.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Congenital alveolar capillary dysplasia: rare cause of persistent pulmonary hypertension. | We report on a rare case of fatal congenital alveolar capillary dysplasia. The newborn boy of a 37 weeks' normal gestation suffered from persistent pulmonary hypertension without any cardiovascular malformation and died at the age of 4 weeks despite intensive treatment. The autopsy tissue was examined histologically, i... | ['Bronchopulmonary Dysplasia', 'Capillaries', 'Fatal Outcome', 'Humans', 'Immunohistochemistry', 'Infant, Newborn', 'Lung', 'Male', 'Persistent Fetal Circulation Syndrome', 'Pulmonary Alveoli'] | 9,353,836 | [['C08.381.520.750.500', 'C16.614.521.125'], ['A07.015.461.165'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A statistically rule-based decision support system for the management of patients with suspected liver disease. | The paper describes how a decision support system in liver diseases, mostly oriented to prediction of the necessity for liver biopsy, has been developed. The system designed is a hybrid one and consists of two parts: logical and statistical. The logical part contains rules, formulated on the basis of current medical kn... | ['Algorithms', 'Biopsy', 'Decision Making, Computer-Assisted', 'Decision Trees', 'Discriminant Analysis', 'Humans', 'Liver Diseases', 'Liver Function Tests', 'Predictive Value of Tests', 'Probability', 'Software', 'Software Design'] | 8,231,421 | [['G17.035', 'L01.224.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['L01.313.500.750.100'], ['G17.162.500'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['B01.050.150.900.649.313.988.400.112.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Characterization of alpha-gliadin genes from diploid wheats and the comparative analysis with those from polyploid wheats. | To carry out the comparative analysis of alpha-gliadin genes on A genomes of diploid and polyploid wheats, 8 full-length alpha-gliadin genes, including 3 functional genes and 5 pseudogenes, were obtained from diploid wheats, among which 2, 2 and 4 alpha-gliadin genes were isolated from T. urartu, T. monococcum and T. b... | ['Amino Acid Sequence', 'Conserved Sequence', 'Diploidy', 'Genes, Plant', 'Genome, Plant', 'Gliadin', 'Molecular Sequence Data', 'Phylogeny', 'Polyploidy', 'Pseudogenes', 'Sequence Analysis, Protein', 'Triticum'] | 18,186,192 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.580'], ['G05.700.264'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.365'], ['D12.776.765.433.500.500.400', 'D12.776.765.725.500.500.400'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['C23.550.210.702', 'G05.365.590.175... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Metabolic disorders and inflammation are associated with familial combined hyperlipemia. | BACKGROUND: Familial Combined Hyperlipidemia (FCH) is related to different metabolic disorders. The objective of this study was to evaluate the presence of alterations of hydrocarbonated metabolism and lipid profile together with inflammatory and adhesion molecules in subjects with FCH compared to controls.METHODS: 75 ... | ['Adult', 'Cholesterol, HDL', 'Female', 'Humans', 'Hyperlipidemia, Familial Combined', 'Inflammation', 'Male', 'Phenotype'] | 30,201,373 | [['M01.060.116'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.398.450', 'C18.452.584.500.500.438', 'C18.452.648.398.450'], ['C23.550.470'], ['G05.695']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Elucidation of the reaction mechanisms and diastereoselectivities of phosphine-catalyzed [4 + 2] annulations between allenoates and ketones or aldimines. | The phosphine-catalyzed [4 + 2] annulations between allenoates and electron-poor trifluoromethyl ketones or N-tosylbenzaldimine dipolarophiles have been investigated in continuum solvation using density functional theory (DFT) calculations. The detailed reaction mechanisms as well as the high cis-diastereoselectivities... | ['Alkadienes', 'Catalysis', 'Cyclization', 'Imines', 'Ketones', 'Molecular Structure', 'Phosphines', 'Quantum Theory', 'Stereoisomerism'] | 22,903,528 | [['D02.455.326.271.665.146'], ['G02.130'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D02.491'], ['D02.522'], ['G02.111.570', 'G02.466'], ['D01.695.525', 'D02.705.621'], ['H01.671.579.800'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Turbulent flow as a cause for underestimating coronary flow reserve measured by Doppler guide wire. | BACKGROUND: Doppler-tipped coronary guide-wires (FW) are well-established tools in interventional cardiology to quantitatively analyze coronary blood flow. Doppler wires are used to measure the coronary flow velocity reserve (CFVR). The CFVR remains reduced in some patients despite anatomically successful coronary angi... | ['Artifacts', 'Blood Flow Velocity', 'Coronary Circulation', 'Coronary Vessels', 'Echocardiography, Doppler', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Middle Aged', 'Nonlinear Dynamics', 'Reproducibility of Results', 'Sensitivity and Speci... | 16,553,954 | [['E05.047'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.324'], ['A07.015.114.269', 'A07.015.908.194'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
[The Lady Windermere syndrome: clinical and bacteriological data and progress in seven cases]. | Described by Reich and Johnson in 1992 [2], the Lady Windermere syndrome occurs exclusively in non-smoking women over the age of 60 years, without significant pre-existing pulmonary disease. It comprises bronchial dilatation, typically in the middle lobe and lingula, together with secondary infection by atypical mycoba... | ['Aged', 'Aged, 80 and over', 'Coinfection', 'Disease Progression', 'Female', 'Humans', 'Lung Diseases', 'Middle Aged', 'Mycobacterium Infections, Nontuberculous', 'Radiography, Thoracic', 'Respiratory Tract Infections', 'Retrospective Studies', 'Syndrome'] | 22,682,598 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.218'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['M01.060.116.630'], ['C01.150.252.410.040.552.475'], ['E01.370.350.700.730'], ['C01.748', 'C08.730'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.50... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Seizures induced by abrupt discontinuation of alprazolam. | Two patients had grand mal seizures following abrupt discontinuation of short-term treatment with alprazolam. Alprazolam's pharmacokinetic and clinical properties are discussed in relation to withdrawal reactions. | ['Adult', 'Alprazolam', 'Anti-Anxiety Agents', 'Benzodiazepines', 'Epilepsy, Tonic-Clonic', 'Female', 'Half-Life', 'Humans', 'Kinetics', 'Male', 'Mental Disorders', 'Substance Withdrawal Syndrome'] | 6,150,649 | [['M01.060.116'], ['D03.633.100.079.080.030'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D03.633.100.079.080'], ['C10.228.140.490.375.290'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['F03'], ['C25.775.835', 'F03.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Psychometric Properties of the Inventory of Attitudes Toward Seeking Mental Health Services (Chinese Version). | ABSTRACTResearch on underutilization patterns of mental health services among older Chinese immigrants is limited, partly due to the absence of translated, psychometrically sound measures for assessing attitudes towards seeking help. In this study we interviewed 200 older Chinese Canadian immigrants using a translated ... | ['Aged', 'Asian Continental Ancestry Group', 'Attitude to Health', 'Canada', 'China', 'Emigrants and Immigrants', 'Factor Analysis, Statistical', 'Help-Seeking Behavior', 'Humans', 'Mental Disorders', 'Mental Health Services', 'Middle Aged', 'Patient Acceptance of Health Care', 'Psychometrics', 'Surveys and Questionnai... | 29,552,991 | [['M01.060.116.100'], ['M01.686.508.200'], ['F01.100.150', 'N05.300.150'], ['Z01.107.567.176'], ['Z01.252.474.164'], ['M01.189'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['F01.145.813.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F04.408', 'N02.421.461'], ['M01.060.116.63... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Depression among cancer patients. | This study was done to investigate the frequency of co-morbidity and to demonstrate the best method for assessing depression among cancer patients. The subjects were 50 (25 male and 25 female) cancer patients and 50 (25 male and 25 female) medically ill patients. All subjects were interviewed by psychiatrists and were ... | ['Adult', 'Aged', 'Comorbidity', 'Cross-Sectional Studies', 'Depressive Disorder', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Neoplasms', 'Patient Care Team', 'Personality Inventory', 'Sick Role'] | 9,014,227 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['C04'], ['N04.590.715'], ['F04.711.647... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Small intestinal epithelial brush border enzymatic changes in suckling mice infected with reovirus type 3. | Suckling mice infected with reovirus type 3 were examined for changes in the epithelial brush border of the small intestine. After 3 days of infection with reovirus type 3, no significant changes were found in intestinal morphology or activity of any enzymes tested. After 6 days, villi were shortened and blunted with l... | ['Alkaline Phosphatase', 'Animals', 'Animals, Suckling', 'Intestines', 'Leucyl Aminopeptidase', 'Mammalian orthoreovirus 3', 'Mice', 'Microvilli', 'Reoviridae Infections', 'alpha-Glucosidases', 'beta-Galactosidase'] | 6,250,121 | [['D08.811.277.352.650.035'], ['B01.050'], ['B01.050.050.293'], ['A03.556.124'], ['D08.811.277.656.350.100.511', 'D08.811.277.656.350.555.700', 'D08.811.277.656.675.555.700'], ['B04.820.223.719.590.550.700'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.180.565'], ['C01.925.782.791'], ['D08.811.277.450.420.05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interaction between caspase-8 activation and endoplasmic reticulum stress in glycochenodeoxycholic acid-induced apoptotic HepG2 cells. | The accumulation of hydrophobic bile acid, such as glycochenodeoxycholic acid (GCDCA), in the liver has been thought to induce hepatocellular damage in human chronic cholestatic liver diseases. We previously reported that GCDCA-induced apoptosis was promoted by both mitochondria-mediated and endoplasmic reticulum (ER) ... | ['Apoptosis', 'Biological Transport', 'Caspase 8', 'Cell Culture Techniques', 'Cell Line, Tumor', 'Cell Survival', 'Cytochromes c', 'Endoplasmic Reticulum', 'Glycochenodeoxycholic Acid', 'Humans', 'Immunohistochemistry', 'Mitochondria, Liver', 'Oxidative Stress', 'Reverse Transcriptase Polymerase Chain Reaction', 'bcl-... | 17,928,124 | [['G04.146.954.035'], ['G03.143'], ['D08.811.277.656.262.500.126.550.800', 'D08.811.277.656.300.200.126.550.800', 'D12.644.360.024.285.037', 'D12.644.360.075.405.550.800', 'D12.644.360.075.421.037', 'D12.776.157.057.018.037', 'D12.776.476.024.320.025', 'D12.776.476.075.405.550.800', 'D12.776.476.075.421.037'], ['E01.37... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of porosity, tissue density, and mechanical properties on radial sound speed in human cortical bone. | PURPOSE: The purpose of this study was to investigate the effect of simultaneous changes in cortical porosity, tissue mineral density, and elastic properties on radial speed of sound (SOS) in cortical bone. The authors applied quantitative pulse-echo (PE) ultrasound techniques that hold much potential especially for sc... | ['Adult', 'Aged', 'Biomechanical Phenomena', 'Calcification, Physiologic', 'Computer Simulation', 'Cortical Bone', 'Elasticity', 'Female', 'Femur', 'Humans', 'Male', 'Middle Aged', 'Models, Theoretical', 'Organ Size', 'Porosity', 'Ultrasonic Waves', 'Ultrasonography', 'X-Ray Microtomography'] | 27,147,315 | [['M01.060.116'], ['M01.060.116.100'], ['G01.154.090', 'G01.374.089'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['L01.224.160'], ['A10.165.265.521'], ['G01.374.590'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Identification of the motor vehicle accident victim who abuses alcohol: an opportunity to reduce trauma. | OBJECTIVE: We hypothesized that a poor driving history and alcohol abuse, evident in a large number of people injured in automobile accidents, contribute to repeated injury, and that treatment for alcohol abuse may reduce vehicular trauma.METHOD: Patients (N = 150) admitted to the emergency surgical service because of ... | ['Accidents, Traffic', 'Adult', 'Alcoholic Intoxication', 'Alcoholism', 'Automobile Driving', 'Ethanol', 'Female', 'Humans', 'Kentucky', 'Male', 'Substance-Related Disorders', 'Wounds and Injuries'] | 8,913,997 | [['N06.850.135.392'], ['M01.060.116'], ['C25.775.100.175', 'F03.900.100.300'], ['C25.775.100.250', 'F03.900.100.350'], ['I03.125'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.400', 'Z01.107.567.875.510.400'], ['C25.775', 'F03.900'], ['C26']] | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteria. | Polyphosphate kinase 1 (PPK1) helps bacteria to survive under stress. The ppk1 gene of Mycobacterium tuberculosis was overexpressed in Escherichia coli and characterized. Residues R230 and F176, predicted to be present in the head domain of PPK1, were identified as residues critical for polyphosphate (polyP)-synthesizi... | ['Anaerobiosis', 'Bacterial Proteins', 'Down-Regulation', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Ligases', 'Mycobacterium smegmatis', 'Mycobacterium tuberculosis', 'Oxidative Stress', 'Phosphotransferases (Phosphate Group Acceptor)', 'Point Mutation', 'Polyphosphates', 'Sigma Factor', 'Signal Tra... | 17,630,969 | [['G02.111.062', 'G03.078'], ['D12.776.097'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['D08.811.464'], ['B03.510.024.962.500.720.662', 'B03.510.460.400.410.552.552.720.662'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancement by HSP90 inhibitor of PGD2-stimulated HSP27 induction in osteoblasts: Suppression of SAPK/JNK and p38 MAP kinase. | Heat shock protein (HSP) 90 that is ubiquitously expressed in various tissues is a major molecular chaperone. We have previously demonstrated that prostaglandin D2 (PGD2), a bone remodeling factor, elicits the expression of HSP27, a small HSP, through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) a... | ['3T3 Cells', 'Animals', 'Anthracenes', 'Benzamides', 'Drug Synergism', 'Gene Expression Regulation', 'HSP27 Heat-Shock Proteins', 'HSP90 Heat-Shock Proteins', 'Imidazoles', 'Isoindoles', 'JNK Mitogen-Activated Protein Kinases', 'Mice', 'Osteoblasts', 'Phosphorylation', 'Prostaglandin D2', 'Protein Kinase Inhibitors', ... | 30,946,899 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['D02.455.426.559.847.117', 'D04.615.117'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['G07.690.773.968.477'], ['G05.308'], ['D12.776.580.216.270.625'], ['D12.776.580.216.380'], ['D03.383.129.308'], ['D03.633.100.513'], ['D08.811.913.696... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resistance evolution and mechanisms to ALS-inhibiting herbicides in Capsella bursa-pastoris populations from China. | Capsella bursa-pastoris is a serious broadleaf weed in winter wheat fields in China. It has evolved high levels of resistance to acetolactate synthase (ALS) inhibiting herbicides and has caused substantial losses of wheat yield in recent years. We monitored the herbicide resistance of Capsella bursa-pastoris collected ... | ['Acetolactate Synthase', 'Arylsulfonates', 'Capsella', 'Herbicide Resistance', 'Herbicides', 'Mutation', 'Nicotinic Acids', 'Plant Proteins', 'Point Mutation', 'Pyrimidines', 'Sulfonamides'] | 31,400,779 | [['D08.811.913.200.324', 'D12.776.331.049'], ['D02.886.645.600.080.050'], ['B01.650.940.800.575.912.250.157.244'], ['G07.690.773.984.443'], ['D27.720.031.700.366', 'D27.888.723.366'], ['G05.365.590'], ['D03.066.515', 'D03.383.725.547'], ['D12.776.765'], ['G05.365.590.675'], ['D03.383.742'], ['D02.065.884', 'D02.886.590... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle. | Mutations in the nuclear gene encoding the mitochondrial protein frataxin are responsible for the neurological disorder Friedreich ataxia (FA). Yeast strains with a deletion in the frataxin homologue YFH1 accumulate excess iron in mitochondria and demonstrate mitochondrial damage. We show that in the absence of YFH1, m... | ['Biological Transport', 'Friedreich Ataxia', 'Iron', 'Iron-Binding Proteins', 'Mitochondria', 'Phosphotransferases (Alcohol Group Acceptor)'] | 9,988,680 | [['G03.143'], ['C10.228.140.252.700.150', 'C10.228.854.787.200', 'C10.574.500.825.200', 'C16.320.400.780.200', 'C18.452.660.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D12.776.157.427', 'D12.776.556.579'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D08.811.913.696.620']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The diagnostic utilities of anti-agalactosyl IgG antibodies, anti-cyclic citrullinated peptide antibodies, and rheumatoid factors in rheumatoid arthritis. | The purpose of this study was to investigate the diagnostic utilities of anti-agalactosyl IgG antibody (CARF), anti-cyclic citrullinated peptide (CCP) antibody and rheumatoid factor (RF) in rheumatoid arthritis (RA), non-RA rheumatic diseases, and chronic viral hepatitis. The authors determined serum levels of CARF and... | ['Antibodies, Anti-Idiotypic', 'Arthritis, Rheumatoid', 'Biomarkers', 'Enzyme-Linked Immunosorbent Assay', 'Hepatitis B, Chronic', 'Humans', 'Immunoglobulin G', 'Peptides, Cyclic', 'ROC Curve', 'Rheumatoid Factor', 'Scleroderma, Systemic', "Sjogren's Syndrome", 'Statistics, Nonparametric'] | 20,012,964 | [['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D23.101'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C01.221.250.500.100', ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Gonadal hormone actions on the morphology of the vasopressinergic innervation of the adult rat brain. | Castration of adult male rats resulted in a gradual decrease in vasopressin fiber density over a period of 15 weeks to a point where hardly any fibers were found in those areas where the fibers probably are derived from the bed nucleus of the stria terminalis. The original fiber density could be restored by testosteron... | ['Animals', 'Castration', 'Diencephalon', 'Female', 'Gonadal Steroid Hormones', 'Histocytochemistry', 'Male', 'Rats', 'Rats, Inbred Strains', 'Septum Pellucidum', 'Testosterone', 'Vasopressins'] | 6,722,551 | [['B01.050'], ['E04.270.282', 'E04.950.165'], ['A08.186.211.200.317'], ['D06.472.334.851'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer. | OBJECTIVE: Oesophageal cancer is the seventh most common cause of cancer-related death worldwide. Disease relapse is frequent and treatment options are limited.DESIGN: To identify new biomarker-defined therapeutic approaches for patients with oesophageal cancer, we integrated the genomic profiles of 17 oesophageal tumo... | ['Antineoplastic Agents', 'Cell Line, Tumor', 'Drug Discovery', 'Esophageal Neoplasms', 'Humans', 'Pharmacogenetics', 'Pharmacogenomic Testing', 'Proto-Oncogene Proteins c-myc', 'Pyrazoles', 'Pyrimidines', 'RNA Interference', 'Receptor, ErbB-2', 'Signal Transduction', 'Xenograft Model Antitumor Assays'] | 28,830,912 | [['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.273.343.750', 'H01.158.703.052', 'H02.628.4... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Multicenter comprehensive methodological and technical analysis of 832 pressurized intraperitoneal aerosol chemotherapy (PIPAC) interventions performed in 349 patients for peritoneal carcinomatosis treatment: An international survey study. | BACKGROUND: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new drug delivery method offered in selected patients suffering from non-resectable peritoneal carcinomatosis (PC). As reported experience is still limited, we conducted a survey among active PIPAC centers aiming to report their technical approac... | ['Administration, Inhalation', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Appendiceal Neoplasms', 'Carcinoma', 'Cisplatin', 'Colorectal Neoplasms', 'Doxorubicin', 'Female', 'Gastrointestinal Neoplasms', 'Humans', 'Injections, Intraperitoneal', 'Male', 'Mesothelioma', 'Mitomycin', 'Organ... | 29,526,367 | [['E02.319.267.050'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.274.476.411.184.290', 'C06.301.371.411.184.290', 'C06.405.249.411.184.290', 'C06.405.469.110.417.290', 'C06.405.469.491.184.290'], ['C04.557.470.200'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['C04.588... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Erythropoietin levels with treatment of obstructive sleep apnea. | The effect of nasal continuous positive pressure (CPAP) treatment on erythropoietin (EPO) was examined by measuring diurnal serum EPO levels before and twice (over the 3rd day and over 1 day on recall after > or = 1 mo of therapy) after initiation of treatment in 12 obstructive sleep apnea syndrome patients with normal... | ['Adult', 'Aged', 'Blood Gas Monitoring, Transcutaneous', 'Circadian Rhythm', 'Erythropoietin', 'Female', 'Humans', 'Hypoxia', 'Male', 'Middle Aged', 'Oxygen', 'Positive-Pressure Respiration', 'Sleep Apnea Syndromes'] | 8,567,573 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.124.100.100.600.100', 'E01.370.370.380.600.100', 'E01.370.386.700.100.600.100', 'E05.200.124.100.100.600.100'], ['G07.180.562.190'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
New insights on the comma-less theory. | The comma-less hypothesis represents a theoretical effort to describe one of the steps in the early evolution of the translation apparatus. This hypothesis emphasizes the advantages that a RNY coding pattern would have provided in a primitive RNA adaptor-catalyst system. This theory has been debated for years, both in ... | ['Amino Acids', 'Base Sequence', 'Biological Evolution', 'Codon', 'DNA', 'Genetic Code', 'Models, Genetic', 'RNA'] | 1,726,735 | [['D12.125'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308'], ['G05.360.335'], ['E05.599.395.397'], ['D13.444.735']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding. | Altered nuclear size is associated with many cancers, and determining whether cancer-associated changes in nuclear size contribute to carcinogenesis necessitates an understanding of mechanisms of nuclear size regulation. Although nuclear import rates generally positively correlate with nuclear size, NTF2 levels negativ... | ['Active Transport, Cell Nucleus', 'Animals', 'Cell Nucleus', 'Cell Nucleus Size', 'Humans', 'Nucleocytoplasmic Transport Proteins', 'Pregnancy Proteins', 'Protein Binding', 'Xenopus laevis', 'ran GTP-Binding Protein'] | 26,823,604 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.670.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.750', 'D12.776.543.585.750'], ['D12.776.780'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.090.180.610.500.562'], ['D08.811.277.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nanoscale mid-infrared evaluation of the miscibility behavior of blends of dextran or maltodextrin with poly(vinylpyrrolidone). | Determining the extent of miscibility of amorphous components is of great importance for certain pharmaceutical systems, in particular for polymer-polymer and polymer-small molecule blends. In this study, the application of standard atomic force microscopy (AFM) measurements combined with nanoscale mid-infrared (mid-IR... | ['Dextrans', 'Microscopy, Atomic Force', 'Polymers', 'Polysaccharides', 'Povidone'] | 22,483,035 | [['D05.750.078.562.272', 'D09.698.365.272'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D09.698'], ['D02.455.326.271.884.533.699', 'D03.383.773.812.615', 'D05.750.716.721.838', 'D25.720.716.721.838', 'J01.637.051.720.716.721.838']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein. | Phage display is a widely used technology for the isolation of peptides and proteins with specific binding properties from large libraries of these molecules. A drawback of the common phagemid/helper phage systems is the high infective background of phages that do not display the protein of interest, but are propagated... | ['Bacteriophages', 'Capsid Proteins', 'DNA-Binding Proteins', 'Humans', 'Immunoglobulin Variable Region', 'Mutation', 'Nucleic Acid Amplification Techniques', 'Peptide Library', 'Recombinant Fusion Proteins', 'U937 Cells', 'Viral Fusion Proteins'] | 12,771,223 | [['B04.123'], ['D12.776.964.970.600.550'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.650.500', 'D12.776.124.486.485.680.650.500', 'D12.776.124.486.485.797', 'D12.776.124.790.651.680.650.500', 'D12.776.124.790.651.797', 'D12.776.377.715.548.680.650.500', 'D12.776.377.715.548.797... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stereotactic Body Radiotherapy for Oligometastasis: Opportunities for Biology to Guide Clinical Management. | Oligometastasis refers to a state of limited metastatic disease burden, in which surgical or ablative treatment to all known visible metastases holds promise to extend survival or even effect cure. Stereotactic body radiotherapy is a form of radiation treatment capable of delivering a high biologically effective dose o... | ['Humans', 'Neoplasms', 'Patient Selection', 'Quality of Life', 'Radiosurgery'] | 27,441,744 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E05.581.500.653', 'N04.590.731'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
An investigation of interpretive bias in insomnia: an analog study comparing normal and poor sleepers. | STUDY OBJECTIVES: Cognitive theories state that psychological disorders are associated with, and are possibly maintained by, interpretive biases, which are tendencies to make threatening interpretations of ambiguous stimuli. Recent models of insomnia have highlighted the importance of cognitive processes. The aim of th... | ['Adolescent', 'Adult', 'Anxiety', 'Bias', 'Cognitive Behavioral Therapy', 'Data Interpretation, Statistical', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Severity of Illness Index', 'Sleep Initiation and Maintenance Disorders', 'Surveys and Questionnaires'] | 17,068,991 | [['M01.060.057'], ['M01.060.116'], ['F01.470.132'], ['N05.715.350.150', 'N06.850.490.500'], ['F04.754.137.350'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Indications for tonsillectomy in childhood from the current viewpoint]. | Any discussion of tonsillectomy must necessarily be based on the function and pathophysiology of the palatine tonsils. Their unique anatomic structure illustrates their main immunological function: to recognize and process the transgressors from the environment, to transfer the resulting immunological information to th... | ['Age Factors', 'Angina Pectoris', 'Child', 'Child, Preschool', 'Humans', 'Hyperplasia', 'Infant', 'Palatine Tonsil', 'Tonsillectomy', 'Tonsillitis'] | 6,727,503 | [['N05.715.350.075', 'N06.850.490.250'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['M01.060.703'], ['A04.623.603.925', 'A10.549.580', 'A14.724.603.925', 'A15.382.520.604.580'], ['E04.580.848... | ['Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Implications of platinum-group element accumulation along U.S. roads from catalytic-converter attrition. | Automobile catalytic converters are dispersing platinum-group elements (PGEs) Rh, Pt, and Pd into the environment (1-3). This paper represents the first detailed study to assess the PGE content of soils and grasses from U.S. roadsides. These soils were analyzed using cation exchange pretreatment and ultrasonic nebulize... | ['Air Pollutants', 'Environmental Monitoring', 'Lead', 'Platinum', 'Poaceae', 'Rhodium', 'Soil Pollutants', 'Tissue Distribution', 'Vehicle Emissions'] | 11,642,438 | [['D27.888.284.101'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.268.556.435', 'D01.552.544.435'], ['D01.268.556.690', 'D01.268.956.734', 'D01.552.544.690'], ['B01.650.940.800.575.912.250.822'], ['D01.268.556.793', 'D01.268.956.781', 'D01.552.544.793'], ['D27.888.284.756'], ['G03.787.917', 'G07.690.725.949'], ['... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The perceptions of nurse teachers regarding the preparation for their role in Project 2000 programmes. | This paper discusses the findings related to the perceptions of nurse teachers regarding the preparation for their role in Project 2000 programmes. Data were collected by utilising three rounds of a Delphi survey with a panel of experts made up of Grade 2 nurse teachers. The panel of 201 respondents was obtained from 2... | ['Attitude of Health Personnel', 'Delphi Technique', 'Education, Nursing, Continuing', 'England', 'Faculty, Nursing', 'Humans', 'Nursing Education Research', 'Role'] | 1,448,024 | [['F01.100.050', 'N05.300.100'], ['L01.906.197'], ['I02.358.212.450', 'I02.358.462.399'], ['Z01.542.363.300'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.390.413', 'H02.478.395.413', 'I02.358.462.612', 'N04.590.233.508.613.413'], ['F01.8... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Contrast pooling in videofluoroscopic swallowing study as a risk factor for pneumonia in children with dysphagia. | OBJECTIVE: To determine if laryngeal contrast pooling on a videofluoroscopic swallowing study increases the risk for pneumonia in the following 6 months in children with dysphagia. Secondarily, to determine in the same population, if laryngeal abnormalities or syndromic disorders increase the risk for pneumonia in the ... | ['Adolescent', 'Child', 'Child, Preschool', 'Cineradiography', 'Contrast Media', 'Deglutition', 'Deglutition Disorders', 'Female', 'Fluoroscopy', 'Humans', 'Infant', 'Infant, Newborn', 'Larynx', 'Male', 'Pneumonia', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors'] | 26,092,551 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.700.225.469'], ['D27.505.259.500', 'D27.720.259'], ['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A04.329'], ['C01.748.610', 'C08.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pituitary adenylate cyclase-activating polypeptide (PACAP) promotes both survival and neuritogenesis in PC12 cells through activation of nuclear factor êB (NF-êB) pathway: involvement of extracellular signal-regulated kinase (ERK), calcium, and c-REL. | The pituitary adenylate cyclase-activating polypeptide (PACAP) is a trophic factor that promotes neuronal survival and neurite outgrowth. However, the signaling pathways and the transcriptional mechanisms involved are not completely elucidated. Our previous studies aimed at characterizing the transcriptome of PACAP-dif... | ['Active Transport, Cell Nucleus', 'Animals', 'Calcium Signaling', 'Cell Nucleus', 'Cell Survival', 'MAP Kinase Signaling System', 'Mitogen-Activated Protein Kinase 3', 'NF-kappa B p52 Subunit', 'Neurites', 'PC12 Cells', 'Pituitary Adenylate Cyclase-Activating Polypeptide', 'Proto-Oncogene Proteins c-rel', 'Rats'] | 23,564,451 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.050'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.346'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D08.811.913.696.620.682.700.567.249.750', 'D12.644.360.450.169.750', 'D12.776.476.450... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient soluble expression of active recombinant human cyclin A2 mediated by E. coli molecular chaperones. | Bacterial expression of human proteins continues to present a critical challenge in protein crystallography and drug design. While human cyclin A constructs have been extensively characterized in complex with cyclin dependent kinase 2 (CDK2), efforts to express the monomeric human cyclin A2 in Escherichia coli in a sta... | ['Cyclin A2', 'Escherichia coli', 'Humans', 'Molecular Chaperones', 'Protein Binding', 'Recombinant Fusion Proteins', 'Solubility'] | 25,956,535 | [['D12.644.360.262.100.200', 'D12.776.167.218.100.200', 'D12.776.476.262.100.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.580'], ['G02.111.679', 'G03.808'], ['D12.776.828.300'], ['G02.805']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solvent effects on the physicochemical properties of the cross-linked histidine-tyrosine ligand of cytochrome c oxidase. | Density functional theory was used to explore the effects of aqueous solvation on the structure, vibrational frequencies, and the electronic absorption spectrum of 2-(4-methylimidazol-1-yl)-phenol (Me-ImPhOH), a chemical analogue of the cross-linked histidine-tyrosine Cu(B) ligand of cytochrome c oxidase. In addition, ... | ['Chemical Phenomena', 'Electron Transport Complex IV', 'Gases', 'Histidine', 'Ligands', 'Models, Chemical', 'Oxidation-Reduction', 'Solvents', 'Spectrophotometry, Infrared', 'Thermodynamics', 'Tyrosine'] | 20,415,431 | [['G02'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['D01.362'], ['D12.125.072.329', 'D12.125.142.308'], ['D27.720.470.480'], ['E05.599.495'], ['G02.700', 'G03.295.531'], ['D27.720.844'], ['E05.196.712.726.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemotactic peptides induce phosphorylation and activation of MEK-1 in human neutrophils. | Extracellular signal-regulated kinase (Erk) (mitogen-activated protein (MAP) kinase) is rapidly activated when neutrophils are stimulated. Several isoforms of MAP/Erk kinase (MEK), a kinase capable of phosphorylating and activating Erk, have been identified, but their distribution and differential roles in leukocytes a... | ['Amino Acid Sequence', 'Calcium', 'Calcium-Transporting ATPases', 'Egtazic Acid', 'Enzyme Activation', 'Glutathione Transferase', 'Humans', 'Isoenzymes', 'MAP Kinase Kinase 1', 'Mitogen-Activated Protein Kinase Kinases', 'Molecular Sequence Data', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Phosphorylat... | 8,034,695 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['G02.111.263', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Impulsive traits and 5-HT2A receptor promoter polymorphism in alcohol dependents: possible association but no influence of personality disorders. | OBJECTIVE: Impulsive behavior in alcoholics puts them at serious risk of severer course of disease and has been related to the serotonergic neurotransmission dysfunction. The aim of this study is to investigate the association between impulsive aggression in alcohol dependents with regard to the G-1438A polymorphism in... | ['Adult', 'Aggression', 'Alcoholism', 'Alleles', 'Disruptive, Impulse Control, and Conduct Disorders', 'Female', 'Humans', 'Male', 'Middle Aged', 'Personality Disorders', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'Receptor, Serotonin, 5-HT2A', 'Receptors, Serotonin'] | 11,287,798 | [['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['C25.775.100.250', 'F03.900.100.350'], ['G05.360.340.024.340.030'], ['F03.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.675'], ['G05.365.795'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inappropriate surgical chemoprophylaxis and surgical site infection rate at a tertiary care teaching hospital. | OBJECTIVES: This study aimed to analyze the pattern of surgical chemoprophylaxis, surgical site infection rate, and to check rationality of surgical chemoprophylaxis based on Kunin's criteria.MATERIALS AND METHODS: A prospective, observational study was performed on patients undergoing surgery, in a tertiary care teach... | ['Adolescent', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Female', 'Hospitals, Teaching', 'Humans', 'Inappropriate Prescribing', 'Length of Stay', 'Male', 'Middle Aged', 'Prospective Studies', 'Surgical Wound Infection', 'Tertiary Healthcare', 'Young Adult'] | 23,287,545 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.490', 'N02.421.450.500.249'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Depression in primary caregivers of patients listed for liver or kidney transplantation. | BACKGROUND: No studies have examined depression in primary caregivers of adult patients listed for liver or kidney transplantation.OBJECTIVE: To determine the prevalence of depression among primary caregivers of patients listed for liver or kidney transplantation and to compare these 2 groups.DESIGN: A cross-sectional ... | ['Aged', 'Caregivers', 'Cost of Illness', 'Cross-Sectional Studies', 'Depression', 'Family', 'Female', 'Health Services Needs and Demand', 'Humans', 'Kidney Transplantation', 'Life Change Events', 'Liver Transplantation', 'Male', 'Mass Screening', 'Middle Aged', 'Missouri', 'Pilot Projects', 'Prevalence', 'Psychiatric ... | 17,944,158 | [['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['F01.829.263', 'I01.880.853.150'], ['N03.349.380.420', 'N05... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Retrograde subintimal recanalization of a radial artery occlusion after coronary angiography using the palmar loop technique. | We report interventional management of critical hand ischemia after transradial coronary angiography. The radial artery occlusion was confirmed by Doppler ultrasound and digital subtraction angiography. The radial artery was opened using retrograde recanalization technics through the palmar arch. After guidewire passag... | ['Adult', 'Arterial Occlusive Diseases', 'Coronary Angiography', 'Drug-Eluting Stents', 'Female', 'Humans', 'Radial Artery', 'Stents', 'Treatment Outcome', 'Vascular Surgical Procedures'] | 25,623,261 | [['M01.060.116'], ['C14.907.137'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E07.695.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.740'], ['E07.695.750'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E04.100.81... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fatigue in adults with Marfan syndrome, occurrence and associations to pain and other factors. | This study aims to investigate how fatigue affects adults with verified Marfan syndrome (MFS) in their daily lives, by examining fatigue levels and prevalence of severe fatigue compared to the general Norwegian population and individuals with other comparable chronic conditions. We investigated associations between soc... | ['Activities of Daily Living', 'Adult', 'Aged', 'Cross-Sectional Studies', 'Fatigue', 'Female', 'Humans', 'Male', 'Marfan Syndrome', 'Middle Aged', 'Pain', 'Prevalence', 'Public Health Surveillance', 'Quality of Life', 'Risk Factors', 'Self Report', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Young Adul... | 24,719,044 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.099.674', 'C14.240.400.725', 'C14.280.400.725', 'C16... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Testicular involvement in peripubertal gonadotropin levels and accessory sex organ weight of male hamsters. | This study evaluates the influence of testicular secretions during development in male hamsters on peripubertal gonadotropin levels. Castration or sham operations were performed on the day of birth (Day 1), Day 5, 10, or 20 of life. Repeated plasma samples on Days 20-60 at 10-day intervals were taken via orbital sinus ... | ['Animals', 'Cricetinae', 'Follicle Stimulating Hormone', 'Genitalia, Male', 'Luteinizing Hormone', 'Male', 'Orchiectomy', 'Organ Size', 'Sexual Maturation', 'Testis', 'Testosterone'] | 3,127,833 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['A05.360.444'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Restriction endonuclease mapping and molecular cloning of the human herpesvirus 6 variant B strain Z29 genome. | Human herpesvirus 6(HHV-6) variants A and B differ in cell tropism, reactivity with monoclonal antibodies, restriction endonuclease profiles, and epidemiology. Nonetheless, comparative nucleotide and amino acid sequences from several genes indicate that the viruses are very highly conserved genetically, The B variant i... | ['Antibodies, Monoclonal', 'Base Sequence', 'Child', 'Chromosomes, Human', 'Cloning, Molecular', 'Genetic Variation', 'Genome, Viral', 'Herpesviridae Infections', 'Herpesvirus 6, Human', 'Humans', 'Molecular Sequence Data', 'Restriction Mapping', 'Sequence Homology, Nucleic Acid', 'Telomere'] | 8,634,027 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['E05.393.220'], ['G05.365'], ['G05.360.340.358.840'], ['C01.925.256.466'], ['B04.280.382.150.750.40... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Bone responses to titanium implants surface-roughened by sandblasted and double etched treatments in a rabbit model. | OBJECTIVE: The objective of this study was to investigate bone responses to titanium implants surface-roughened by sandblasted and double-etched treatments in a rabbit model.STUDY DESIGN: Sixty implants of 10 mm in length (30 machined and 30 roughened) were inserted into femurs of 30 rabbits and 30 implants of 8 mm in ... | ['Analysis of Variance', 'Animals', 'Dental Etching', 'Dental Implants', 'Dental Polishing', 'Device Removal', 'Femur', 'Implants, Experimental', 'Microscopy, Electron, Scanning', 'Osseointegration', 'Rabbits', 'Surface Properties', 'Tibia', 'Titanium', 'Torque'] | 18,602,288 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E06.931.475'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.298'], ['E04.199'], ['A02.835.232.043.150'], ['E07.695.340'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G11.427.213.140.570', 'G16.762... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Differences in gait complexity and variability between children with and without developmental coordination disorder. | We used elliptical Fourier analysis (EFA) to examine potential differences in the complexity and variability of gait of children with (N=10) and without (N=10) Developmental Coordination Disorder (DCD). Children with DCD generated movement patters with larger variability and complexity than typically developing (TD) ch... | ['Child', 'Female', 'Fourier Analysis', 'Gait', 'Humans', 'Male', 'Motor Skills Disorders', 'Movement', 'Task Performance and Analysis'] | 18,829,321 | [['M01.060.406'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.625.813'], ['G07.568', 'G11.427.410'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Differential response to avian leukosis virus infection exhibited by two chicken lines. | Infection of susceptible chickens with avian leukosis virus (ALV) results in the development of bursal lymphomas. These neoplasms develop within the bursa of Fabricius following a latent period of several months. The response exhibited by two previously uncharacterized chicken lines to ALV infection has been examined. ... | ['Animals', 'Avian Leukosis', 'Avian Leukosis Virus', 'Base Sequence', 'Cells, Cultured', 'Chick Embryo', 'Chickens', 'Cloning, Molecular', 'DNA', 'DNA Restriction Enzymes', 'Fibroblasts', 'Nucleic Acid Hybridization', 'Oncogenes'] | 6,328,748 | [['B01.050'], ['C01.925.782.815.096', 'C01.925.928.120', 'C04.557.337.372.216', 'C04.619.531.216', 'C22.131.094'], ['B04.613.807.070.100', 'B04.820.650.070.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Outcomes of bleeding peptic ulcers: a prospective study. | BACKGROUND AND AIM: Bleeding peptic ulcers can be due to Helicobacter pylori (H. pylori) infection, use of non-steroidal anti-inflammatory drugs (NSAIDs), or idiopathic causes. The aim of this prospective study was to identify the clinical outcomes of bleeding peptic ulcers related to different causes.METHODS: A total ... | ['Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Peptic Ulcer Hemorrhage', 'Prospective Studies', 'Treatment Outcome'] | 17,944,885 | [['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.405.227.700', 'C23.550.414... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Environmental factors and multiple sclerosis severity: a descriptive study. | Growing evidence suggests that environmental factors play a key role in the onset of multiple sclerosis (MS). This study was conducted to examine whether environmental factors may also be associated with the evolution of the disease. We collected data on smoking habits, sunlight exposure and diet (particularly consumpt... | ['Adolescent', 'Adult', 'Aged', 'Diet', 'Disease Progression', 'Environmental Exposure', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Patient Acuity', 'Sunlight', 'Ultraviolet Rays', 'Vitamin D', 'Young Adult'] | 24,950,063 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.203.650.240'], ['C23.550.291.656'], ['N06.850.460.350'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['E05.318.308.980.438.475.456', 'N05.715.360.300.80... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of charcoal amendment on adsorption, leaching and degradation of isoproturon in soils. | The effects of charcoal amendment on adsorption, leaching and degradation of the herbicide isoproturon in soils were studied under laboratory conditions. The adsorption data all fitted well with the Freundlich empirical equation. It was found that the adsorption of isoproturon in soils increased with the rate of charco... | ['Adsorption', 'Charcoal', 'Herbicides', 'Phenylurea Compounds', 'Soil Pollutants'] | 21,237,529 | [['G01.030', 'G02.020'], ['D01.268.150.150'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D02.065.950.681', 'D02.455.426.559.389.703'], ['D27.888.284.756']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human, bovine, canine and rat thyroglobulin promoter sequences display species-specific differences in an in vitro study. | The proximal promoter regions of the thyroglobulin gene from man, beef, dog and rat were compared by transient expression in primary cultured dog thyrocytes. All four promoter regions were able to control properly the expression of a reporter gene in response to cyclic AMP stimulation. Surprisingly, despite extensive s... | ['Animals', 'Base Sequence', 'Cattle', 'Chloramphenicol', 'Colforsin', 'Cyclic AMP', 'Dogs', 'Gene Expression Regulation', 'Genes, Regulator', 'Growth Hormone', 'Humans', 'In Vitro Techniques', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Polymerase Chain Reaction', 'Promoter Regions, Genetic', 'Rats', 'Se... | 8,388,339 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Glomerular filtration rate and N-terminal pro-brain natriuretic peptide as predictors of cardiovascular mortality in vascular patients. | OBJECTIVES: The purpose of this work was to assess the prognostic role of glomerular filtration rate (GFR) and NT-terminal pro-B-type natriuretic peptide (NT-proBNP) for mortality end points in the vascular population.BACKGROUND: The GFR and NT-proBNP have been shown to predict mortality end points in free-living and l... | ['Aged', 'Biomarkers', 'Cardiovascular Diseases', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Male', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Predictive Value of Tests', 'Prognosis', 'Prospective Studies', 'Survival Rate', 'Vascular Diseases'] | 17,543,637 | [['M01.060.116.100'], ['D23.101'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Natural history of anterior chest wall numbness after plating of clavicle fractures: educating patients. | OBJECTIVES: Improved patient outcomes after plating of displaced clavicle fractures have been demonstrated by recent clinical studies. Many of these patients, however, complain of anterior chest wall numbness after this procedure; we hypothesize that numbness likely persists long term for many patients, but without eff... | ['Adolescent', 'Adult', 'Aged', 'Bone Plates', 'Clavicle', 'Disease Progression', 'Female', 'Fracture Fixation, Internal', 'Humans', 'Hypesthesia', 'Male', 'Middle Aged', 'Patient Education as Topic', 'Prospective Studies', 'Recovery of Function', 'Thoracic Wall', 'Treatment Outcome', 'Young Adult'] | 24,662,990 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['A02.835.232.087.227'], ['C23.550.291.656'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.751.791.500', 'C23.888.592.763.770.500'], ['M01.060.116.630'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Educational resources for vascular laboratory education in vascular surgery residencies and fellowships: Survey of Vascular Surgery Program Directors. | OBJECTIVE: The Registered Physician in Vascular Interpretation (RPVI) credential is a prerequisite for certification by the Vascular Surgery Board of the American Board of Surgery. Of concern, as more current trainees and recent program graduates take the Physician Vascular Interpretation (PVI) examination, vascular su... | ['Certification', 'Clinical Competence', 'Curriculum', 'Education, Medical, Graduate', 'Educational Measurement', 'Fellowships and Scholarships', 'Humans', 'Internship and Residency', 'Program Evaluation', 'Surgeons', 'Surveys and Questionnaires', 'Time Factors', 'United States', 'Vascular Surgical Procedures'] | 30,622,008 | [['N03.706.110.120', 'N05.700.200.190'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.337.350', 'I02.358.399.350'], ['I02.399'], ['N03.219.483.838.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['E05.337.820', 'N04.761.685', 'N05.715.... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Asthma control and differences in management practices across seven European countries. | Failure to follow asthma management guidelines may result in poor asthma control for many patients. The Asthma Insights and Reality in Europe (AIRE) survey, a multi-national survey assessing the level of asthma control from the patients perspective in seven Western European countries, previously demonstrated that the G... | ['Adolescent', 'Adrenergic beta-Agonists', 'Adult', 'Asthma', 'Child', 'Child, Preschool', 'Europe', 'Female', 'Glucocorticoids', 'Guideline Adherence', 'Humans', 'Male', 'Middle Aged', 'Morbidity', 'Patient Acceptance of Health Care', 'Practice Guidelines as Topic', "Practice Patterns, Physicians'", 'Respiratory Funct... | 11,905,548 | [['M01.060.057'], ['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.542'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.15... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bone scintigraphy of calciphylaxis: a syndrome of vascular calcification and skin necrosis. | Calciphylaxis is a highly morbid syndrome of vascular calcification and skin necrosis, the pathophysiology of which remains largely elusive. We report a patient with end-stage renal disease and multiple painful skin lesions who underwent a bone scan for extremity pain. Increased tracer accumulation was seen in the subc... | ['Aged', 'Bone and Bones', 'Calcinosis', 'Calciphylaxis', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Necrosis', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Skin Ulcer', 'Syndrome', 'Technetium Tc 99m Medronate', 'Vascular Diseases'] | 16,237,294 | [['M01.060.116.100'], ['A02.835.232', 'A10.165.265'], ['C18.452.174.130'], ['C18.452.174.130.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['C23.550.717'], ['E01.370.350.710', 'E01.370.384.730'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.41... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Epidemiological situation of tuberculosis in children and youth of Poland]. | After the Second World War tuberculosis was a very serious health problem in Poland. Tuberculosis in children and youth constituted an important part of the morbidity in the whole population. In 1957 almost 27% of newly detected cases concerned children (19.9%) and adolescents (7%). This percentage decreased systematic... | ['Adolescent', 'Adult', 'Age Distribution', 'Child', 'Child, Preschool', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Poland', 'Prevalence', 'Tuberculosis', 'Tuberculosis, Pulmonary'] | 11,228,602 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['M01.060.70... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Selective N-methyl-D-aspartate (NMDA) antagonists increase gastric motility in the rat. | Systemic administration of selective NMDA antagonists, such as CPP, APH, ketamine and MK-801, increased spontaneous gastric motility of the rat in a dose-dependent manner, and they prevented the NMDA-evoked depression of gastric motility. On the other hand, a broad spectrum excitatory amino acid antagonist, kynurenate,... | ['2-Amino-5-phosphonovalerate', 'Animals', 'Autonomic Nervous System', 'Dibenzocycloheptenes', 'Dizocilpine Maleate', 'Dose-Response Relationship, Drug', 'Male', 'Piperazines', 'Rats', 'Rats, Inbred Strains', 'Receptors, N-Methyl-D-Aspartate', 'Receptors, Neurotransmitter', 'Stomach'] | 1,973,272 | [['D12.125.070.950.100', 'D12.125.740.025'], ['B01.050'], ['A08.800.050'], ['D02.455.426.559.847.181.384', 'D04.615.181.384'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.383.606'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age-dependent morphology of NADPH diaphorase-positive amacrine cells in the mouse retina. | NADPH diaphorase-positive amacrine cells (NAC) were studied in retinal whole mount preparation of mice, ranging from 1 day to 30 months of age. Following a peak in number and size during early development at postnatal day 14, their number and distribution remained well preserved up to senescence. Functional considerati... | ['Aging', 'Amacrine Cells', 'Animals', 'Cell Shape', 'Mice', 'NADPH Dehydrogenase', 'Retina'] | 22,472,000 | [['G07.345.124'], ['A08.675.358.050', 'A08.675.650.850.500', 'A09.371.729.831.500', 'A11.671.358.050', 'A11.671.650.850.500'], ['B01.050'], ['G04.320'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.682.608.550'], ['A09.371.729']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fenestration of the supraclinoid internal carotid artery. | A twenty-eight year old woman presenting with subarachnoid hemorrhage was found at angiography to have a left anterior cerebral-anterior communicating artery aneurysm. Also identified was a fenestration of the right supraclinoid internal carotid artery with an associated accessory middle cerebral artery. This appears t... | ['Adult', 'Carotid Artery, Internal', 'Cerebral Angiography', 'Female', 'Humans', 'Intracranial Aneurysm', 'Ischemic Attack, Transient', 'Subarachnoid Hemorrhage'] | 3,607,619 | [['M01.060.116'], ['A07.015.114.186.200.230'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association of H-2 types with genetic control of immune reponsiveness to IgG (gamma2a) allotypes in the mouse. | Immune responsiveness to IgG allotypes in the mouse was found to be controlled by an immune response gene Ir-IgG linked to the H-2 locus. This was demonstrated by the analysis of the immune response to BALB/c IgG (gamma2a) myeloma proteins in mice of various H-2 types from five different linkage groups of immunoglobuli... | ['Animals', 'Antibody Formation', 'Binding Sites, Antibody', 'Epitopes', 'Genes', 'Histocompatibility', 'Histocompatibility Antigens', 'Immunization', 'Immunoglobulin Fab Fragments', 'Immunoglobulin Fc Fragments', 'Immunoglobulin G', 'Isoantigens', 'Mice', 'Mice, Inbred A', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', ... | 4,117,189 | [['B01.050'], ['G12.450.050.370.250'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['D23.050.550'], ['G05.360.340.024.340'], ['G12.875.519'], ['D23.050.301.500', 'D23.050.705.552'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.31... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Leucovorin and folic acid regimens for selective expansion of murine 5,10-methylenetetrahydrofolate pools. | Mice bearing subcutaneously implanted EMT6 mammary adenocarcinoma were treated with leucovorin or folic acid by continuous subcutaneous infusion or bolus intraperitoneal injection. (6R)-5,10-Methylenetetrahydrofolate pools in cytosolic extracts of the tumor, marrow, and gut were measured by analysis of the ternary comp... | ['Animals', 'Bone Marrow', 'Female', 'Folic Acid', 'Intestinal Mucosa', 'Leucovorin', 'Mice', 'Mice, Inbred BALB C', 'Neoplasms, Experimental', 'Polyglutamic Acid', 'Tetrahydrofolates'] | 7,534,077 | [['B01.050'], ['A15.382.216'], ['D03.633.100.733.631.400'], ['A03.556.124.369', 'A10.615.550.444'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['C04.619', 'E05.598.500.49... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurements of the solar UVR protection provided by shade structures in New Zealand primary schools. | To reduce ultraviolet radiation (UVR) exposure during childhood, shade structures are being erected in primary schools to provide areas where children can more safely undertake outdoor activities. This study to evaluate the effectiveness of existing and purpose built shade structures in providing solar UVR protection w... | ['Erythema', 'Humans', 'New Zealand', 'Schools', 'Sunscreening Agents', 'Ultraviolet Rays'] | 15,264,956 | [['C17.800.229', 'C23.888.885.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['I02.783', 'J03.832'], ['D27.505.696.706.776.800', 'D27.505.954.444.695', 'D27.720.269.800', 'D27.720.799.763.764'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.7... | ['Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
A probabilistic model for sequence alignment with context-sensitive indels. | Probabilistic approaches for sequence alignment are usually based on pair Hidden Markov Models (HMMs) or Stochastic Context Free Grammars (SCFGs). Recent studies have shown a significant correlation between the content of short indels and their flanking regions, which by definition cannot be modelled by the above two a... | ['Algorithms', 'Bayes Theorem', 'Computer Simulation', 'Genome, Human', 'Genome-Wide Association Study', 'Humans', 'INDEL Mutation', 'Likelihood Functions', 'Markov Chains', 'Models, Genetic', 'Models, Statistical', 'Reference Standards', 'Sequence Alignment', 'Sequence Analysis, DNA'] | 21,951,055 | [['G17.035', 'L01.224.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['L01.224.160'], ['G05.360.340.350'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.050.150.900.649.313.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors. | New antipsychotic drugs are needed because current therapy is ineffective for many schizophrenics and because treatment is often accompanied by extrapyramidal symptoms and dyskinesias. This paper describes the design, synthesis, and evaluation of a series of related (aminomethyl)benzamides in assays predictive of antip... | ['Adrenergic Agents', 'Animals', 'Antipsychotic Agents', 'Avoidance Learning', 'Catalepsy', 'Cerebral Cortex', 'Conditioning, Psychological', 'Corpus Striatum', 'Dopamine Agents', 'Humans', 'Male', 'Piperazines', 'Piperidines', 'Rats', 'Rats, Sprague-Dawley', 'Rats, Wistar', 'Receptors, Adrenergic, alpha-1', 'Receptors... | 9,622,541 | [['D27.505.519.625.050', 'D27.505.696.577.050'], ['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F02.463.425.097', 'F02.463.785.373.173'], ['C10.597.350.200', 'C23.888.592.350.200'], ['A08.186.211.200.885.287.500'], ['F02.463.425.179'], ['A08.186.211.200.885.287... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of the sympathetic innervation on uterine electromyographic activity in nonpregnant ovariectomized sheep under estrogen supplementation. | The aims of the present study were to characterize the sympathetic innervation of the nonpregnant sheep uterus, to determine the catecholamine content in myometrium (MYO) and endometrium, and to study the effects of chemical sympathectomy (CHSPX) on uterine catecholamine content and on uterine electromyographic (EMG) a... | ['Animals', 'Dinoprost', 'Dopamine', 'Electromyography', 'Endometrium', 'Estradiol', 'Female', 'Immunohistochemistry', 'Myometrium', 'Norepinephrine', 'Ovariectomy', 'Oxidopamine', 'Sheep', 'Sympathectomy, Chemical', 'Sympathetic Nervous System', 'Tyrosine 3-Monooxygenase', 'Uterus'] | 1,352,148 | [['B01.050'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E01.370.405.255', 'E01.370.530.255'], ['A05.360.319.679.490'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E01.370.225.500.607.512', 'E01.370.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Tempol improves xanthine oxidoreductase-mediated vascular responses to nitrite in experimental renovascular hypertension. | Upregulation of xanthine oxidoreductase (XOR) increases vascular reactive oxygen species (ROS) levels and contributes to nitroso-redox imbalance. However, XOR can generate nitric oxide (NO) from nitrite, and increased superoxide could inactivate NO formed from nitrite. This study tested the hypothesis that XOR contribu... | ['Animals', 'Antioxidants', 'Blood Pressure', 'Cyclic N-Oxides', 'Disease Models, Animal', 'Humans', 'Hypertension, Renovascular', 'Nitric Oxide', 'Nitrites', 'Rats', 'Reactive Oxygen Species', 'Spin Labels', 'Xanthine Dehydrogenase'] | 27,078,869 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.661.243'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.331.490', 'C13.351.968.419.331.490', 'C14.907.489.631.485'], ['D01.339.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A New Algorithm for Counting Independent Motifs in Probabilistic Networks. | Biological networks provide great potential to understand how cells function. Motifs are topological patterns which are repeated frequently in a specific network. Network motifs are key structures through which biological networks operate. However, counting independent (i.e., non-overlapping) instances of a specific mo... | ['Algorithms', 'Animals', 'Cardiovascular Diseases', 'Cell Cycle', 'Computational Biology', 'Gene Regulatory Networks', 'Gorilla gorilla', 'Humans', 'Models, Genetic', 'Pan troglodytes', 'Pongo', 'Probability', 'Species Specificity', 'Uncertainty'] | 29,994,098 | [['G17.035', 'L01.224.050'], ['B01.050'], ['C14'], ['G04.144'], ['H01.158.273.180', 'L01.313.124'], ['G05.360.080.689.360'], ['B01.050.150.900.649.313.988.400.112.400.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['B01.050.150.900.649.313.988.400.112.400.620'], ['B01.050.150.900.649.313.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans. | Sphingolipids are ubiquitous membrane constituents whose metabolites function as signaling molecules in eukaryotic cells. Sphingosine 1-phosphate, a key sphingolipid second messenger, regulates proliferation, motility, invasiveness, and programmed cell death. These effects of sphingosine 1-phosphate and similar phospho... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Caenorhabditis elegans', 'Cloning, Molecular', 'DNA Primers', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Lysophospholipids', 'Mice', 'Molecular Sequence Data', 'Recombinant Proteins', 'Saccharomyces cerevisiae',... | 12,682,045 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.500.294.400.875.660.250.250'], ['E05.393.220'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.310'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Protein deficiency reduces natural antitumor immunity. | Clinical data have shown that neoplastic diseases and/or related therapies frequently result in protein depletion of tumor-bearing patients. Depressions of acquired and specific immunity caused by protein depletion are well known. In an experimental model protein depletion was induced by lack of nutritional protein in ... | ['Animals', 'Blood Proteins', 'Bone Marrow', 'Bone Marrow Cells', 'Cytotoxicity, Immunologic', 'Killer Cells, Natural', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Protein-Energy Malnutrition', 'Reference Values', 'Spleen', 'Tumor Cells, Cultured'] | 3,121,178 | [['B01.050'], ['D12.776.124'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['G12.287'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tobacco cytochrome b5: cDNA isolation, expression analysis and in vitro protein targeting. | A full-length clone encoding cytochrome b5 has been isolated from a tobacco leaf cDNA library in lambda gt11 by PCR using degenerate primers. This cDNA encodes a protein of 139 residues which exhibits a high degree of homology to other cytochrome b5s, the message for which is expressed predominantly in developing seeds... | ['Amino Acid Sequence', 'Base Sequence', 'Biological Transport', 'Cell Compartmentation', 'Cytochromes b5', 'DNA, Complementary', 'Endoplasmic Reticulum', 'Genes, Plant', 'Genome', 'Molecular Sequence Data', 'Multigene Family', 'Plants, Toxic', 'RNA Caps', 'RNA, Messenger', 'Sequence Analysis, DNA', 'Sequence Homology,... | 8,049,375 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143'], ['G04.128'], ['D08.244.187.500', 'D12.776.422.220.187.500'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['A11.284.430.214.190.875.248'], ['G05.360.340.024.340.393', 'G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Accidents with bicycles and motorcycles. The injury pattern, costs, and possibilities for prevention]. | This review comprises all 641 patients subjected to inpatient treatment in 1976, 1980 and 1984 at the Basel district hospital after accidents involving bicycles or motorcycles. A study of the case histories--supplemented by phone conversations--yielded the following results: Accidents involving bicycles or motor-driven... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bicycling', 'Cost Control', 'Cross-Sectional Studies', 'Disability Evaluation', 'Female', 'Hospitalization', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Motorcycles', 'Switzerland', 'Wounds and Injuries'] | 1,353,295 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['I03.450.642.845.140'], ['N03.219.151.160'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.30... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients. | (1) Background: In literature it is reported that 20-30% of psoriatic patients evolve to psoriatic arthritis over time. Currently, no specific biochemical markers can either predict progression to psoriatic arthritis or response to therapies. This study aimed to identify osteoimmunological markers applicable to clinica... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthritis, Psoriatic', 'Biomarkers', 'Case-Control Studies', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Psoriasis', 'ROC Curve', 'Young Adult'] | 31,717,649 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.116.900.853.625.800.424', 'C05.550.114.145', 'C05.550.114.865.800.424', 'C17.800.859.675.175'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Salvage by volume reduction of chronic allograft rejection in emphysema. | BACKGROUND: We hypothesized that native lung volume reduction surgery (LVRS) would improve respiratory function in patients who had previously undergone single lung transplantation for emphysema and who were disabled by obliterative bronchiolitis.METHODS: Seven single lung transplant recipients who had advanced bronchi... | ['Aged', 'Bronchiolitis Obliterans', 'Chronic Disease', 'Female', 'Forced Expiratory Volume', 'Graft Rejection', 'Humans', 'Lung', 'Lung Transplantation', 'Male', 'Middle Aged', 'Pulmonary Emphysema', 'Salvage Therapy', 'Vital Capacity'] | 10,194,032 | [['M01.060.116.100'], ['C08.127.446.135.140', 'C08.381.495.146.135.140'], ['C23.550.291.500'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E04.928.600.495', 'E04.936.450.495'], ['M01.060.116.630'], ['C08.381.495.389.750'], ['E02.89... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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