Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Borrelia burgdorferi linear plasmid 38 is dispensable for completion of the mouse-tick infectious cycle. | Borrelia burgdorferi, the causative agent of Lyme disease, exists in a complex enzootic cycle, transiting between its vector, Ixodes ticks, and a diverse range of vertebrate hosts. B. burgdorferi linear plasmid 38 (lp38) contains several genes that are differentially regulated in response to conditions mimicking the ti... | ['Animals', 'Arachnid Vectors', 'Borrelia burgdorferi', 'Female', 'Genetic Vectors', 'Ixodes', 'Lyme Disease', 'Mice', 'Plasmids', 'Virulence Factors'] | 21,708,994 | [['B01.050'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['G05.360.337'], ['B01.050.500.131.166.132.832.400.425'], ['C01.150.252.400.536', 'C01.150.252.400.794.352.250', 'C01.920.930.513'], ['B01.050.150.900.649.313.992.635.505.500'], ['G0... | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Phosphagens and glycogen content in skeletal muscle after treadmill training in young and old rats. | The concentration of creatine phosphate (CrP), ATP, ADP, AMP and glycogen were measured in extensor digitorum longus (EDL) and in quadriceps muscles of 3, 6, 24, and 27 months old male Wistar rats groups. Young (3 months) and old (24 months) rats were trained for 12 weeks, 3 days a week, with running exercise session. ... | ['Adenine Nucleotides', 'Adenosine Diphosphate', 'Adenosine Monophosphate', 'Adenosine Triphosphate', 'Aging', 'Animals', 'Energy Metabolism', 'Glycogen', 'Male', 'Muscles', 'Phosphocreatine', 'Physical Conditioning, Animal', 'Rats'] | 6,539,680 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G07.345.124']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Emotional stimuli and motor conversion disorder. | Conversion disorder is characterized by neurological signs and symptoms related to an underlying psychological issue. Amygdala activity to affective stimuli is well characterized in healthy volunteers with greater amygdala activity to both negative and positive stimuli relative to neutral stimuli, and greater activity ... | ['Adult', 'Aged', 'Amygdala', 'Conversion Disorder', 'Emotions', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Motor Cortex', 'Neuropsychological Tests', 'Reaction Time', 'Stress, Psychological', 'Young Adult'] | 20,371,508 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['F03.875.300'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['F04.711.513'],... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reaction of deoxyguanosine with nitrous acid. | We reinvestigated the reaction of dGuo in the presence of nitrous acid by reversed phase HPLC (RPLC) analysis. When 10 mM deoxyguanosine (dGuo) was treated with 100 mM NaNO2 in 3.0 M acetate buffer (pH 3.7) at 37 degrees C, unknown peak appeared in large amount (yield 19.7% at 2 h, 28.7% at 6 h). The yield of this newl... | ['Chromatography, High Pressure Liquid', 'Deoxyguanosine', 'Hydrogen-Ion Concentration', 'Mutagens', 'Nitrous Acid'] | 8,841,605 | [['E05.196.181.400.300'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570.583.454.240'], ['G02.300'], ['D27.888.569.468'], ['D01.029.260.575', 'D01.625.600']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-construals and values in different cultural and socioeconomic contexts. | In this study the authors investigated (a) how individuational and relational self-orientations, as well as self-directed and other-directed values, are related to one another, and (b) how these self- and value orientations differ across 2 cultural (i.e., 422 Turkish and 441 American university students) and 2 socioeco... | ['Adult', 'Culture', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Social Behavior', 'Social Identification', 'Socioeconomic Factors', 'Surveys and Questionnaires'] | 16,259,380 | [['M01.060.116'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.145.813'], ['F01.145.813.708'], ['I01.880.853.996', 'N01.824'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Identification of the in vitro phosphorylation sites on Gs alpha mediated by pp60c-src. | Overexpression of pp60c-src in mouse fibroblasts potentiates both agonist-induced signalling through beta-adrenergic receptors and cyclic AMP accumulation in response to cholera toxin [Bushman, Wilson, Luttrell, Moyers and Parsons (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 7462-7466; Moyers, Bouton and Parsons (1993) Mol... | ['Amino Acid Sequence', 'Animals', 'Birds', 'Cattle', 'Chromatography, High Pressure Liquid', 'GTP-Binding Proteins', 'Mice', 'Molecular Sequence Data', 'Peptide Fragments', 'Phosphopeptides', 'Phosphorylation', 'Phosphotyrosine', 'Proto-Oncogene Proteins pp60(c-src)', 'Receptors, Adrenergic, beta', 'Recombinant Protei... | 7,530,445 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.248'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.300'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['D12.644.541'], ['D12.644.717'], ['G02.111.665', 'G02.60... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Execution of BMP-4-induced apoptosis by p53-dependent ER dysfunction in myeloma and B-cell hybridoma cells. | Bone morphogenic protein (BMP)-4 inhibits proliferation and induces the apoptosis of myeloma cells. However, little is known about the molecular mechanisms of how BMP-4 executes this apoptosis. In this report, we investigated the roles of p53 and the endoplasmic reticulum (ER) in BMP-4-induced apoptosis of mouse hybrid... | ['Animals', 'Apoptosis', 'B-Lymphocytes', 'Bone Morphogenetic Protein 4', 'Bone Morphogenetic Proteins', 'Cell Proliferation', 'Endoplasmic Reticulum', 'Flow Cytometry', 'Humans', 'Hybridomas', 'Immunoblotting', 'Membrane Potentials', 'Mice', 'Mitochondria', 'Multiple Myeloma', 'Reverse Transcriptase Polymerase Chain R... | 16,449,972 | [['B01.050'], ['G04.146.954.035'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.644.276.954.200.400', 'D12.776.467.942.200.400', 'D23.529.942.200.400'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['G04.161.750', 'G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Alpha 2plasmin-inhibitor . plasmin complex (PIC)--useful diagnostic and prognostic parameter]. | To evaluate the diagnostic and prognostic value of PIC, we compared it with the DIC score (which is calculated from platelet count, fibrinogen, FDP, and prothrombin time). We examined 182 samples from 60 patients with coaglo-fibrinolytic abnormalities. For the diagnosis of DIC, the sensitivity of PIC was significantly ... | ['Aged', 'Antifibrinolytic Agents', 'Biomarkers', 'Disseminated Intravascular Coagulation', 'Female', 'Fibrinolysin', 'Humans', 'Male', 'Predictive Value of Tests', 'Prognosis', 'Sensitivity and Specificity', 'alpha-2-Antiplasmin'] | 1,833,570 | [['M01.060.116.100'], ['D27.505.519.421.500', 'D27.505.954.502.270.463.091'], ['D23.101'], ['C15.378.100.220', 'C15.378.463.250', 'C15.378.925.220'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Full backbone assignment and dynamics of the intrinsically disordered dehydrin ERD14. | Dehydrins are a class of stress proteins that belong to the family of Late Embryogenesis Abundant (LEA) proteins in plants, so named because they are highly expressed in late stages of seed formation. In somatic cells, their expression is very low under normal conditions, but increases critically upon dehydration elici... | ['Arabidopsis', 'Arabidopsis Proteins', 'Isotopes', 'Molecular Chaperones', 'Nuclear Magnetic Resonance, Biomolecular', 'Plant Proteins'] | 21,336,827 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D01.496'], ['D12.776.580'], ['E05.196.867.519.550'], ['D12.776.765']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The transition from acute care to home: a review of issues in discharge teaching and a framework for better practice. | Patients are often sent home with complex discharge plans that can become overwhelming and difficult to follow. By contrast, implementing effective teaching at the time of discharge can lead to a decrease in the rate of hospital readmissions and mortality for patients post discharge (Koelling, Johnson, Cody, & Aaronson... | ['Adult', 'Cardiac Rehabilitation', 'Continuity of Patient Care', 'Critical Care', 'Evidence-Based Nursing', 'Female', 'Home Care Services', 'Humans', 'Male', 'Patient Care Planning', 'Patient Discharge', 'Patient Education as Topic'] | 23,984,482 | [['M01.060.116'], ['E02.760.169.063.500.185', 'E02.831.185', 'H02.403.680.600.250', 'N02.421.784.244'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E02.760.190', 'N02.421.585.190'], ['H02.249.875', 'H02.478.197'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of diazepam on orthodontic tooth movement and alveolar bone cAMP levels in cats. | Cyclic AMP has been suggested as a possible intracellular mediator in bone remodeling during tooth movement. Accordingly, an increase in the level of this nucleotide should result in faster tooth movement. Breakdown of cAMP was inhibited by administration of diazepam in eight cats undergoing orthodontic tooth movement;... | ['Alveolar Process', 'Animals', 'Cats', 'Cyclic AMP', 'Diazepam', 'Time Factors', 'Tooth', 'Tooth Movement Techniques'] | 3,017,093 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.079.080.070.216'], ['G01.910.857'], ['A14.549.167.860'], ['E06.658.578.836... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum insulin-like growth factor-I levels among women in Hawaii and Japan with different levels of tofu intake. | Insulin-like growth factor-I (IGF-I) has been proposed as the link between diet and breast cancer risk. Due to their estrogen-like structure, soy isoflavones may affect IGF-I levels in a similar way as exogenous estrogens. In a cross-sectional design, we compared IGF-I levels between women with high and low soy intake.... | ['Breast Neoplasms', 'Cross-Sectional Studies', 'Diet Surveys', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Hawaii', 'Humans', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Isoflavones', 'Japan', 'Mammography', 'Middle Aged', 'Postmenopause', 'Premenopause', 'Risk Factors', 'Soy F... | 17,474,858 | [['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Accidental severance of epidural catheter used in a patient with postoperative delirium]. | A 79-year-old man with an abdominal aortic aneurysm had a lumbar epidural catheter inserted for postoperative pain control of bypass graft surgery with continuous epidural analgesia. Five days after the operation, we noticed that forced traction by the patient with delirium had led to the catheter tip being separated a... | ['Aged', 'Anesthesia, Epidural', 'Catheterization', 'Delirium', 'Equipment Failure', 'Foreign Bodies', 'Humans', 'Male', 'Postoperative Period', 'Spine'] | 15,198,244 | [['M01.060.116.100'], ['E03.155.086.131'], ['E02.148', 'E05.157'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['E05.325'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.750', 'N02.421.585.753.750'], ['A02.835.232.834']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Echocardiographic follow-up of congenital aortic valvular stenosis. | We investigated the morphology of the stenotic aortic valve, the progression of the stenosis, and the onset and progression of aortic regurgitation (AR) in patients with congenital aortic valvular stenosis (AVS). The medical records of 278 patients with AVS were reviewed, with the patients with concomitant lesions besi... | ['Adolescent', 'Aortic Valve Insufficiency', 'Aortic Valve Stenosis', 'Cardiac Catheterization', 'Child', 'Child, Preschool', 'Disease Progression', 'Echocardiography, Doppler, Color', 'Echocardiography, Doppler, Pulsed', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Retrospective Studies'] | 17,111,293 | [['M01.060.057'], ['C14.280.484.048.500'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.656'], ['E01.370.350.130.750.220.220', 'E01.370.350.850.220.220.220', 'E01.370.350.850.850.220.220', 'E01.370.350.850.850.850.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Estimating the contribution of surfactant replacement therapy to the alveolar pool: An in vivo study based on 13 | Variation of the isotopic abundance of selected nutrients and molecules has been used for pharmacological and kinetics studies under the premise that the administered molecule has a different isotopic enrichment from the isotopic background of the recipient subject. The aim of this study is to test the feasibility of a... | ['Animals', 'Biological Products', 'Carbon Isotopes', 'Feasibility Studies', 'Humans', 'Phospholipids', 'Pilot Projects', 'Pulmonary Alveoli', 'Pulmonary Surfactants', 'Rabbits'] | 29,633,450 | [['B01.050'], ['D20.215'], ['D01.268.150.075', 'D01.496.123'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.755'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['A04.411.715'], ['D27.505.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conservative evaluation of space radiation dose equivalent using the glow curve of 7LiF:Mg, Ti (TLD-700). | For conservative evaluation of dose equivalent in space, a simple method using two glow peaks in TLD-700 has been proposed. This method is superior to the method using the two-peak ratio in terms of following the 1990 ICRP recommendation. Dependence of each peak on LET was confirmed using relativistic heavy-ion beams (... | ['Extraterrestrial Environment', 'Gamma Rays', 'Humans', 'Linear Energy Transfer', 'Models, Theoretical', 'Radiation Dosage', 'Radiometry', 'Space Flight', 'Temperature'] | 11,388,727 | [['G01.060.075.159', 'G16.500.275.240'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.154.240.400', 'G02.111.255.400', 'G02.216.400'], ['E05.599'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.799'], ['J01.937.285.850'], ['G01.906.595'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Distribution of silicone oil in prefilled glass syringes probed with optical and spectroscopic methods. | Prefilled glass syringes (PFSs) have become the most commonly used device for the delivery of recombinant protein therapeutics in parenteral formulations. In particular, auto-injectors preloaded with PFSs greatly facilitate the convenient and efficient self-administration of protein therapeutics by patients. Silicone o... | ['Microscopy, Interference', 'Recombinant Proteins', 'Silicone Oils', 'Spectrum Analysis, Raman', 'Syringes'] | 19,634,353 | [['E01.370.350.515.513', 'E05.490.630', 'E05.595.513'], ['D12.776.828'], ['D02.756.650.700.800', 'D05.750.900.850.950', 'D25.720.900.850.950', 'J01.637.051.720.900.850.950'], ['E05.196.822.860', 'E05.196.867.890'], ['E07.877']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Multidrug-resistant Klebsiella pneumoniae in hospital-acquired infections: Concomitant analysis of antimicrobial resistant strains. | BACKGROUND: Hospital-acquired infections caused by K pneumoniae are difficult to eradicate since K pneumoniae carries resistance genes for many antimicrobials, including carbapenems. The study aimed to determine the prevalence of hospital-acquired infections caused by multiple drug-resistant K pneumoniae and identify c... | ['Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Child', 'Ciprofloxacin', 'Cross Infection', 'Drug Resistance, Multiple, Bacterial', 'Female', 'Genotype', 'Humans', 'Imipenem', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Length of Stay', 'Male', 'Meropenem', 'Microbial Sensitivity Tests', ... | 31,830,351 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['D12.776.097'], ['M01.060.406'], ['D03.633.100.810.835.322.186'], ['C01.248', 'C23.550.291.875.500'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neural correlates of motor-sensory temporal recalibration. | The relative timing of a motor-sensory event can be recalibrated after exposure to delayed visual feedback. Here we examined the neural consequences of lag adaptation using event-related potentials (ERPs). Participants tapped their finger on a pad, which triggered a flash either after a short delay (0 ms/50 ms) or a lo... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Analysis of Variance', 'Electroencephalography', 'Evoked Potentials', 'Evoked Potentials, Visual', 'Feedback, Psychological', 'Female', 'Humans', 'Motor Activity', 'Motor Neurons', 'Photic Stimulation', 'Psychometrics', 'Psychomotor Performance', 'Reaction Time', 'S... | 21,600,564 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.649.313.988.400.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular Cloning, Functional Characterization and Nutritional Regulation of the Putative Elongase Elovl5 in the Orange-Spotted Grouper (Epinephelus coioides). | The enzymes involved in the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFAs) are widely studied in fish species, as fish are the main source of n-3 LC-PUFAs for human beings. In the present study, a putative gene for elovl5, which encodes a key enzyme involved in LC-PUFA synthesis, was cloned and funct... | ['Acetyltransferases', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Bass', 'Cloning, Molecular', 'Fatty Acids, Unsaturated', 'Gene Expression Regulation, Enzymologic', 'Molecular Sequence Data', 'Phylogeny'] | 26,950,699 | [['D08.811.913.050.134'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.493.602.105'], ['E05.393.220'], ['D10.251.355'], ['G05.308.320'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Influence of protein and ribonucleic acid synthesis on the replication of the bacteriocinogenic factor Clo DF13 in Escherichia coli cells and minicells. | The influence of ribonucleic acid (RNA) and protein synthesis on the replication of the cloacinogenic factor Clo DF13 was studied in Escherichia coli cells and minicells. In chromosomeless minicells harboring the Clo DF13 factor, Clo DF13 deoxyribonucleic acid (DNA) synthesis is slightly stimulated after inhibition of ... | ['Alkalies', 'Bacterial Proteins', 'Bacteriocins', 'Carbon Radioisotopes', 'Centrifugation, Density Gradient', 'Chloramphenicol', 'DNA Replication', 'DNA, Bacterial', 'DNA, Circular', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Extrachromosomal Inheritance', 'Leucine', 'Mutation', 'Puromycin', 'RNA, Bacterial'... | 4,595,194 | [['D01.045'], ['D12.776.097'], ['D12.776.097.151', 'D12.776.543.695.110'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['E05.181.724.336', 'E05.196.941.336'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['G02.111.225', 'G05.226'], ['D13.444.308.212'], ['D13.444.308.283'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Static pressure-volume curves and effect of positive end-expiratory pressure on gas exchange in adult respiratory distress syndrome. | Fifteen patients with adult respiratory distress syndrome (ARDS) were studied: 11 in the early stage of ARDS (group 1); 4 in the late stage (group 2). The inspiratory and expiratory static pressure-volume (P-V) curves of the respiratory system were compared to the pulmonary shunt (Qsp/Qt) when PEEP was increased; cardi... | ['Adolescent', 'Adult', 'Aged', 'Carbon Dioxide', 'Child', 'Female', 'Functional Residual Capacity', 'Humans', 'Hydrogen-Ion Concentration', 'Intermittent Positive-Pressure Ventilation', 'Male', 'Middle Aged', 'Oxygen', 'Positive-Pressure Respiration', 'Pressure', 'Pulmonary Edema', 'Pulmonary Fibrosis', 'Pulmonary Gas... | 6,409,503 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['M01.060.406'], ['E01.370.386.700.485.750.275', 'G09.772.850.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E02.041.625.790.550', 'E02.880.820.790.550'], ['M01.060.116.630'], ['D01.268.185... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of amaranth and oat bran on blood serum and liver lipids in rats depending on the kind of dietary fats. | The effect of amaranth and oat bran on the lipids of blood and liver in rats depending on the kind of fats in diet was the subject of our study. Sixty male Buffalo rats were fed for 28 days one of six diet containing 15% of fat (lard or sunflower oil), 20% of protein and 0.5% of cholesterol. Amaranth and oat bran added... | ['Animals', 'Avena', 'Cholesterol', 'Diet', 'Dietary Fats', 'Dietary Fiber', 'Eating', 'Hemangiosarcoma', 'Lipid Metabolism', 'Lipids', 'Liver', 'Male', 'Organ Size', 'Rats', 'Rats, Inbred BUF', 'Triglycerides', 'Weight Gain'] | 10,331,211 | [['B01.050'], ['B01.650.940.800.575.912.250.822.060'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.283', 'G10.261.330'], ['C04.557.450.795.390', 'C04.55... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The effect of single periocular injection of methylprednisolone and drainage of suprachoroidal fluid in the treatment of rhegmatogenous retinal detachment combined with choroidal detachment. | PURPOSE: In this study we compared the anatomic and functional outcomes of two steroid treatments on rhegmatogenous retinal detachment (RRD) combined with choroidal detachment (CD), namely treatment with oral prednisolone (1 mg/kg daily) for 3-7 days before vitrectomy or a single periocular injection of methylprednisol... | ['Administration, Oral', 'Adult', 'Aged', 'Choroid Diseases', 'Choroidal Effusions', 'Combined Modality Therapy', 'Drainage', 'Female', 'Glucocorticoids', 'Humans', 'Injections, Intraocular', 'Male', 'Methylprednisolone', 'Middle Aged', 'Prednisolone', 'Prospective Studies', 'Retinal Detachment', 'Treatment Outcome', '... | 30,940,887 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['C11.941.160'], ['C11.250.105', 'C11.941.160.241'], ['E02.186'], ['E02.309', 'E04.237'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.475'], ['D04.210.500.745.432.769.795.539'], ['M01.060.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Designed miniaturization of microfluidic biosensor platforms using the stop-flow technique. | Here, we present a novel approach to increase the degree of miniaturization as well as the sensitivity of biosensor platforms by the optimization of microfluidic stop-flow techniques independent of the applied detection technique (e.g. electrochemical or optical). The readout of the labeled bioassays, immobilized in a ... | ['Biosensing Techniques', 'Humans', 'Microfluidic Analytical Techniques', 'Microfluidics', 'Miniaturization', 'Tetracyclines'] | 27,747,319 | [['E05.601.043'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.588.465'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['J01.897.520'], ['D02.455.426.559.847.562.900', 'D04.615.562.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
'Strong is the new skinny': A content analysis of #fitspiration images on Instagram. | 'Fitspiration' is an online trend designed to inspire viewers towards a healthier lifestyle by promoting exercise and healthy food. This study provides a content analysis of fitspiration imagery on the social networking site Instagram. A set of 600 images were coded for body type, activity, objectification and textual ... | ['Adolescent', 'Adult', 'Body Image', 'Female', 'Humans', 'Male', 'Physical Fitness', 'Qualitative Research', 'Social Media', 'Young Adult'] | 27,611,630 | [['M01.060.057'], ['M01.060.116'], ['F01.752.747.792.110', 'F02.463.593.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['H01.770.644.241.850'], ['L01.178.751', 'L01.224.230.110.500.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Allosteric interactions required for high-affinity binding of dihydropyridine antagonists to Ca(V)1.1 Channels are modulated by calcium in the pore. | Dihydropyridines (DHPs) are an important class of drugs, used extensively in the treatment of angina pectoris, hypertension, and arrhythmia. The molecular mechanism by which DHPs modulate Ca(2+) channel function is not known in detail. We have found that DHP binding is allosterically coupled to Ca(2+) binding to the se... | ['Allosteric Regulation', 'Amino Acid Sequence', 'Calcium', 'Calcium Channel Blockers', 'Calcium Channels, L-Type', 'Isradipine', 'Molecular Sequence Data', 'Protein Conformation', 'Structure-Activity Relationship'] | 16,675,661 | [['G02.111.044'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['D03.383.725.203.310'], ['L01.453.24... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessing collective affect recognition via the Emotional Aperture Measure. | Curiosity about collective affect is undergoing a revival in many fields. This literature, tracing back to Le Bon's seminal work on crowd psychology, has established the veracity of collective affect and demonstrated its influence on a wide range of group dynamics. More recently, an interest in the perception of collec... | ['Adult', 'Affect', 'Behavior Rating Scale', 'Emotions', 'Female', 'Group Processes', 'Humans', 'Male', 'Recognition, Psychology', 'Reproducibility of Results', 'Young Adult'] | 25,809,581 | [['M01.060.116'], ['F01.470.047'], ['F04.711.271'], ['F01.470'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.706'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of growth hormone on maintenance of capillary-like structures in an in vitro model of stromal vascular tissue--results from morphometric analysis. | The in vitro development of a vascular stroma might be a solution for the engineering of vascularized tissues, however, in vitro stability of capillary-like structures is limited. In order to test the influence on maintenance of capillary-like structures, human growth hormone (hGH) was added in concentrations of 0.5, 5... | ['Capillaries', 'Coculture Techniques', 'Endothelial Cells', 'Human Growth Hormone', 'Humans', 'Microscopy, Confocal', 'Neovascularization, Physiologic', 'Stromal Cells', 'Tissue Engineering'] | 15,787,630 | [['A07.015.461.165'], ['E05.481.500.374'], ['A11.436.275'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'], ['G09.330.630'], ['A11.329.830'], ['E05.481.500.311.500', 'J01.293.069.249.500']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Treatment of a cohort of patients with acute myocardial infarction and ST-segment elevation. | BACKGROUND: Although thrombolysis and primary CTA are well-established procedures, they are not administered in a large proportion of the patients with STEMI who arrive to the emergency rooms.OBJECTIVE: Describe initial and final the results in a cohort of STEMI patientsMETHODS: The study included, from hospital admiss... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Epidemiologic Methods', 'Female', 'Fibrinolytic Agents', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Thrombolytic Therapy', 'Time Factors', 'Young Adult'] | 19,629,310 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E05.318', 'N06.850.520'], ['D27.505.519.421.750', 'D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Comparison of jumping and electrodiffusion mechanisms of particle movement in thin membranes. III. Potential clamping in a uniform membrane]. | Electric relaxation of a non-uniform membrane was considered during potential clamp. It is shown that in the case of non-uniformity as a high narrow potential barrier in the middle and deep holes along the membrane edges the electrodiffusion model is adequate to the three-barrier hopping one. | ['Biological Transport', 'Diffusion', 'Mathematics', 'Membranes', 'Models, Biological'] | 1,268,273 | [['G03.143'], ['G01.202', 'G02.196'], ['H01.548'], ['A10.615'], ['E05.599.395']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The cytokine response element of the rat alpha 1-acid glycoprotein gene is a complex of several interacting regulatory sequences. | Expression of the rat alpha 1-acid glycoprotein gene is stimulated by interleukin-1 (IL-1) and interleukin-6 (IL-6) and is synergistically enhanced by the combination of the two. The distal regulatory element (DRE), a 142-base-pair (bp) sequence located 5 kilobase pairs upstream of the transcriptional start site, appea... | ['Animals', 'Base Sequence', 'Biological Factors', 'Cell Line', 'Cytokines', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Genes', 'Humans', 'Interleukin-1', 'Interleukin-6', 'Liver', 'Liver Neoplasms, Experimental', 'Molecular Sequence Data', 'Orosomucoid', 'Plasmids', 'Rats', 'Recombinant Proteins', 'Regulat... | 2,196,441 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D23'], ['A11.251.210'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.776.260'], ['G05.308'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.77... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hydrolyzed Rutin Decreases Worsening of Anaplasia in Glioblastoma Relapse. | BACKGROUND: Gliomas are aggressive and resilient tumors. Progression to advanced stages of malignancy, characterized by cell anaplasia, necrosis, and reduced response to conventional surgery or therapeutic adjuvant, are critical challenges in glioma therapy. Relapse of the disease poses a considerable challenge for man... | ['Anaplasia', 'Animals', 'Apoptosis', 'Brain Neoplasms', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Glioblastoma', 'Humans', 'Hydrolysis', 'Mice', 'Recurrence', 'Rutin', 'Thiobarbituric Acid Reactive Substances'] | 30,868,970 | [['C04.697.045', 'C23.550.727.045'], ['B01.050'], ['G04.146.954.035'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.0... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tissue-specific expression of two structurally different estrogen receptor alpha isoforms along the female reproductive axis of an oviparous species, the rainbow trout. | In oviparous species, in addition to a full-length estrogen receptor alpha (ER alpha), another ER alpha isoform lacking the A domain and exhibiting a ligand-independent transactivation function has been consistently reported. Although both isoforms are expressed in the liver, their respective sites of expression in oth... | ['Animals', 'Autoradiography', 'Estrogen Receptor alpha', 'Female', 'Gene Expression', 'In Situ Hybridization', 'Liver', 'Male', 'Oncorhynchus mykiss', 'Organ Specificity', 'Ovary', 'Pituitary Gland', 'Prosencephalon', 'Protein Isoforms', 'RNA, Messenger', 'Receptors, Estrogen', 'Reverse Transcriptase Polymerase Chain ... | 11,673,274 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D12.776.826.750.350.174'], ['G05.297'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['A03.620'], ['B01.050.150.900.493.817.750.825.580.600'], ['G07.650'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term efficacy of Al3+ for prevention of bioprosthetic heart valve calcification. | AI3+ preincubation has been shown in 21 and 60 day implants to inhibit calcification of glutaraldehyde preserved bovine pericardium (GPBP) in the rat subdermal model. This study was designed to assess the long-term anticalcification efficacy of GPBP AI3+ preincubation. Rat (50-60 gm, male, CD Sprague-Dawley) subdermal ... | ['Aluminum', 'Aluminum Chloride', 'Aluminum Compounds', 'Animals', 'Bioprosthesis', 'Calcinosis', 'Chlorides', 'Heart Valve Prosthesis', 'Male', 'Postoperative Complications', 'Prosthesis Design', 'Rats', 'Rats, Inbred Strains', 'Tissue Preservation'] | 2,252,713 | [['D01.268.557.050', 'D01.552.547.050'], ['D01.056.031', 'D01.210.450.150.025'], ['D01.056'], ['B01.050'], ['E07.695.100'], ['C18.452.174.130'], ['D01.210.450.150', 'D01.248.497.158.215'], ['E07.695.310'], ['C23.550.767'], ['E05.320.550', 'E07.695.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.52... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seroprevalence of Chikungunya Virus after Its Emergence in Brazil. | Chikungunya has had a substantial impact on public health because of the magnitude of its epidemics and its highly debilitating symptoms. We estimated the seroprevalence, proportion of symptomatic cases, and proportion of chronic form of disease after introduction of chikungunya virus (CHIKV) in 2 cities in Brazil. We ... | ['Adolescent', 'Adult', 'Aged', 'Brazil', 'Chikungunya Fever', 'Chikungunya virus', 'Child', 'Child, Preschool', 'Communicable Diseases, Emerging', 'Cross-Sectional Studies', 'Female', 'Humans', 'Incidence', 'Infant', 'Male', 'Middle Aged', 'Population Surveillance', 'Seroepidemiologic Studies', 'Young Adult'] | 29,553,317 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.107.757.176'], ['C01.920.500.078.184', 'C01.925.081.198', 'C01.925.782.930.100.184'], ['B04.820.578.875.054.198'], ['M01.060.406'], ['M01.060.406.448'], ['C01.221.500', 'C23.550.291.531.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The cost-effectiveness of the management of acute sinusitis. | BACKGROUND: Sinusitis is a common medical disease with a tremendous economic impact on health care. Our objective was to determine the most cost-effective strategy for the management of acute sinusitis from the societal and payers' perspectives.METHODS: A Markov disease simulation model was used for comparing four trea... | ['Acute Disease', 'Anti-Bacterial Agents', 'Computer Simulation', 'Cost of Illness', 'Cost-Benefit Analysis', 'Decision Trees', 'Health Care Costs', 'Humans', 'Markov Chains', 'Practice Guidelines as Topic', 'Quality of Life', 'Quality-Adjusted Life Years', 'Sinusitis', 'United States'] | 17,882,914 | [['C23.550.291.125'], ['D27.505.954.122.085'], ['L01.224.160'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['N03.219.151.125'], ['G17.162.500'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.500', 'E05.318.740.996.5... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Role of DL alpha-lipoic acid in gentamicin induced nephrotoxicity. | The effect of DL alpha-lipoic acid on the nephrotoxic potential of gentamicin was examined. Intraperitoneal injection of gentamicin (100 mg/kg/day) to rats resulted in decreased activity of the glycolytic enzymes-hexokinase, phosphoglucoisomerase, aldolase and lactate dehydrogenase. The two gluconeogenic enzymes--gluco... | ['Adenosine Triphosphatases', 'Alcohol Oxidoreductases', 'Animals', 'Citric Acid Cycle', 'Fructose-Bisphosphate Aldolase', 'Gentamicins', 'Gluconeogenesis', 'Glucose-6-Phosphate Isomerase', 'Glycolysis', 'Hexokinase', 'Injections, Intraperitoneal', 'Intubation, Gastrointestinal', 'Kidney', 'Male', 'Phosphoric Monoester... | 7,659,073 | [['D08.811.277.040.025'], ['D08.811.682.047'], ['B01.050'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['D08.811.520.224.062.400'], ['D09.408.051.374'], ['G02.111.158.500', 'G03.191.500'], ['D08.811.399.475.200.350'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['D08.811.913.696.620.300'], ['E... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Community-based approaches and partnerships: innovations in health-service delivery in Bangladesh. | In Bangladesh, rapid advancements in coverage of many health interventions have coincided with impressive reductions in fertility and rates of maternal, infant, and childhood mortality. These advances, which have taken place despite such challenges as widespread poverty, political instability, and frequent natural disa... | ['Bangladesh', 'Communicable Disease Control', 'Community Health Services', 'Community Health Workers', 'Delivery of Health Care', 'Diabetes Mellitus', 'Diffusion of Innovation', 'Family Planning Services', 'Fluid Therapy', 'Forecasting', 'Government Agencies', 'Humans', 'Immunization Programs', 'Interprofessional Rela... | 24,268,607 | [['Z01.252.245.131'], ['N06.850.780.200'], ['N02.421.143'], ['M01.526.485.067.080', 'N02.360.067.080'], ['N04.590.374', 'N05.300'], ['C18.452.394.750', 'C19.246'], ['L01.143.320'], ['N02.421.143.401', 'N02.421.800.249'], ['E02.319.360'], ['I01.320'], ['I01.409.418', 'N03.540.400'], ['B01.050.150.900.649.313.988.400.112... | ['Geographicals [Z]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Combinatorial regulation of transcription factors and microRNAs. | BACKGROUND: Gene regulation is a key factor in gaining a full understanding of molecular biology. Cis-regulatory modules (CRMs), consisting of multiple transcription factor binding sites, have been confirmed as the main regulators in gene expression. In recent years, a novel regulator known as microRNA (miRNA) has been... | ['Animals', 'Embryonic Development', 'Gene Expression Profiling', 'Gene Regulatory Networks', 'Mice', 'MicroRNAs', 'Systems Biology', 'Transcription Factors'] | 21,059,252 | [['B01.050'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.393.332'], ['G05.360.080.689.360'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['H01.158.273.180.800'], ['D12.776.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of active vitamin D administration on muscle mass in hemodialysis patients. | BACKGROUND: Muscle wasting is common and insidious in end-stage renal disease (ESRD). Loss of muscle quantity and quality reduces quality of life and increases mortality in ESRD patients. Additionally, secondary hyperparathyroidism (SHPT) causes muscle atrophy. Meanwhile, vitamin D, which is used for SHPT treatment, pl... | ['Adult', 'Aged', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Prospective Studies', 'Quality of Life', 'Renal Dialysis', 'Vitamin D'] | 24,068,630 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['I01.800', 'K01.752.400... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Signal transduction in the protozoan host Hartmannella vermiformis upon attachment and invasion by Legionella micdadei. | The intracellular pathogens Legionella micdadei and Legionella pneumophila are the two most common Legionella species that cause Legionnaires' disease. Intracellular replication within pulmonary cells is the hallmark of Legionnaires' disease. In the environment, legionellae are parasites of protozoans, and intracellula... | ['Acetylgalactosamine', 'Animals', 'Bacterial Adhesion', 'Endoplasmic Reticulum', 'Galactose', 'Hartmannella', 'Lectins', 'Legionella', 'Microscopy, Electron', 'Phagosomes', 'Phosphorylation', 'Protozoan Proteins', 'Signal Transduction', 'Tyrosine'] | 9,726,850 | [['D09.067.342.356.050'], ['B01.050'], ['G06.099.050'], ['A11.284.430.214.190.875.248'], ['D09.947.875.359.377'], ['B01.046.500.100.700.430'], ['D12.776.503'], ['B03.440.400.425.450.450', 'B03.660.250.460.460'], ['E01.370.350.515.402', 'E05.595.402'], ['A11.284.430.214.190.875.190.700'], ['G02.111.665', 'G02.607.780', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autoantibodies to malondialdehyde-modified epitope in connective tissue diseases and vasculitides. | Malondialdehyde (MDA), a peroxidative end-product released during polyunsaturated fatty acid degradation, reacts strongly with lysine residues of cellular proteins. MDA-modified proteins become immunogenic and may elicit specific autoantibody formation. We hypothesized that systemic diseases in which inflammatory event... | ['Adult', 'Aged', 'Autoantibodies', 'Connective Tissue Diseases', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Female', 'Humans', 'Immunoglobulin M', 'Male', 'Malondialdehyde', 'Middle Aged', 'Vasculitis'] | 7,544,246 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C17.300'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.550'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Population-based study of diagnosis, treatment and prognosis of gastric cancer. | BACKGROUND: Gastric cancer remains a common cancer with a poor prognosis. Improving trends seen in Japan have not yet been observed in Western countries.METHODS: A population-based series of 1329 patients with gastric cancer diagnosed over an 18-year period in C?te d'Or, France, was used to establish time trends in dia... | ['Adult', 'Aged', 'Female', 'France', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Retrospective Studies', 'Stomach Neoplasms', 'Survival Analysis', 'Survival Rate'] | 9,361,617 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bone marrow morphology during haematopoietic stem cell mobilisation with cyclophosphamide in mice. | The aim of the study was to examine the morphology of the bone marrow of mice after stimulation with cyclophosphamide (Cy). The experimental mice were given a single intraperitoneal injection with 250 mg/kg bw cyclophosphamide. After 2, 4 and 6 days of experiment the femurs were obtained for morphological study. On the... | ['Animals', 'Bone Marrow', 'Cyclophosphamide', 'Female', 'Hematopoietic Stem Cell Mobilization', 'Hematopoietic Stem Cells', 'Immunosuppressive Agents', 'Mice', 'Mice, Inbred BALB C', 'Specific Pathogen-Free Organisms'] | 14,655,135 | [['B01.050'], ['A15.382.216'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E02.095.410'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D27.505.696.477.656'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['G06.320.6... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using the dimensions of health to assess motivation among running moms. | The Centers for Disease Control and Prevention (2008) reported that 60% of American women did not engage in the recommended daily amount of physical activity and 25% are not physically active at all. The concept of holistic health or wellness refers to an active process in which an individual's life is influenced by di... | ['Emotions', 'Exercise', 'Female', 'Humans', 'Interviews as Topic', 'Male', 'Mental Health', 'Mothers', 'Motivation', 'Running', 'Social Behavior', 'Spirituality', "Women's Health"] | 21,476,159 | [['F01.470'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F02.418', 'N01.400.500'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['F01.658', 'F01.752.543.500.750... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Named Groups [M]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
The effect of hyaluronan injections into human knees on the number of bone and cartilage wear particles captured by bio-ferrography. | Osteoarthritis is characterized by degradation of cartilage and subchondral bone, releasing wear particles into the synovial fluid. Intra-articular injections of exogenous hyaluronan are often given to patients suffering from osteoarthritis in order to compensate for the reduction in the level of endogenous hyaluronan ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bone and Bones', 'Cartilage', 'Female', 'Humans', 'Hyaluronic Acid', 'Injections, Intra-Articular', 'Knee Joint', 'Magnetics', 'Male', 'Middle Aged', 'Spectrometry, X-Ray Emission', 'Surveys and Questionnaires'] | 20,826,234 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.835.232', 'A10.165.265'], ['A02.165', 'A10.165.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['E02.319.267.530.380'], ['A02.835.583.475'], ['H01.671.493'], ['M01.060.116.630'], ['E05.196.867.800', 'E05.799.830'], ['E05.... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Two forms of activation-induced cytidine deaminase differing in their ability to bind agarose. | BACKGROUND: Activation-induced cytidine deaminase (AID) is a B-cell-specific DNA mutator that plays a key role in the formation of the secondary antibody repertoire in germinal center B cells. In the search for binding partners, protein coimmunoprecipitation assays are often performed, generally with agarose beads.METH... | ['Amino Acid Sequence', 'Animals', 'Chromatography, Gel', 'Cytidine Deaminase', 'Immunoprecipitation', 'Isoenzymes', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Molecular Weight', 'Sepharose'] | 20,111,710 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.181.400.250'], ['D08.811.277.151.486.250'], ['E05.196.150.639', 'E05.478.605'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['L01.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Evaluation test and masking therapy of subjective tinnitus]. | OBJECTIVE: To undergo tinnitus evaluation test and masking therapy of subject tinnitus associated with sensorineural hearing loss as a reference for diagnosis and guiding masking therapy.METHODS: The 66 patients with subject tinnitus were diagnosed as sensorineural hearing loss. Sixty-six patients divide into three gro... | ['Adolescent', 'Adult', 'Aged', 'Audiometry, Pure-Tone', 'Female', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Middle Aged', 'Perceptual Masking', 'Tinnitus', 'Young Adult'] | 19,961,770 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.382.375.060.055'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593.071.594', 'F02.463.593.932.733', 'G07.888.125.594'], ['C09.218.458.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Induction therapy consisting of alternating cycles of ranimustine, vincristine, melphalan, dexamethasone and interferon alpha (ROAD-IN) and a randomized comparison of interferon alpha maintenance in multiple myeloma: a co-operative study in Japan. | This pilot study evaluated the efficacy of a new combination chemotherapy with a newly developed nitrosourea derivative ranimustine and evaluated the efficacy of interferon alpha (IFN-alpha) maintenance in previously untreated patients with multiple myeloma (MM). The induction therapy (ROAD-IN) was a 6-week regimen con... | ['Antineoplastic Combined Chemotherapy Protocols', 'Chi-Square Distribution', 'Connectin', 'Dexamethasone', 'Humans', 'Interferon-alpha', 'Logistic Models', 'Melphalan', 'Multiple Myeloma', 'Muscle Proteins', 'Myeloma Proteins', 'Nitrosourea Compounds', 'Pilot Projects', 'Prospective Studies', 'Remission Induction', 'V... | 10,929,034 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D08.811.913.696.620.682.324', 'D12.776.210.500.246'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Studies on the high-energy gun propellant formulations based on 1,5-diazido-3-nitrazapentane. | This paper discusses the enhancement of ballistic performance of RDX-based high-energy gun propellants by incorporation of the energetic plasticizer 1,5-diazido-3-nitrazapentane into the propellant composition. Compositions containing 1,5-diazido-3-nitrazapentane with varying percentage of cyclotrimethylenetrinitramine... | ['Azides', 'Collodion', 'Explosive Agents', 'Firearms', 'Plasticizers', 'Triazines'] | 19,720,458 | [['D01.625.100', 'D02.159'], ['D25.720.099.500.439', 'J01.637.051.720.099.500.439'], ['D27.720.317'], ['J01.637.870.350'], ['D27.720.760'], ['D03.383.931']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The vagueness of "tradition" and the pain and suffering of children. | The argument presented by Jeffrey Bishop that "tradition" justifies female circumcision is grounded on the assumption that reason is always situated within traditions and that traditions are the foundational source of values. I argue that the concept of tradition is inherently vague and, as such, cannot support the wei... | ['Anthropology, Cultural', 'Circumcision, Female', 'Cultural Characteristics', 'Ethics, Medical', 'Female', 'Humans', 'Pain'] | 18,662,952 | [['I01.076.201'], ['E02.218.085.165', 'E04.085.165', 'E04.950.300.200', 'I01.076.201.450.199'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Hexosaminidase: a biochemical marker for necrotizing enterocolitis in the preterm infant. | To evaluate hexosaminidase as a biochemical marker for the early detection of necrotizing enterocolitis in preterm infants, 33 preterm infants without necrotizing enterocolitis and 18 preterm infants with necrotizing enterocolitis had hexosaminidase activity measured during the course of their hospitalization. Although... | ['Clinical Enzyme Tests', 'Enterocolitis, Pseudomembranous', 'Female', 'Hexosaminidases', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Time Factors'] | 6,691,551 | [['E01.370.225.124.200', 'E05.196.427.200', 'E05.200.124.200'], ['C01.150.252.410.222.310', 'C06.405.205.596.800', 'C06.405.469.363.800'], ['D08.811.277.450.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increase of serum angiopoietin-2 during pregnancy is suppressed in women with preeclampsia. | BACKGROUND: Numerous recent reports demonstrated that changes in serum levels of angiogenesis-related factors were associated with preeclampsia. Here, we determined the serum concentration of angiopoietin-2 (Ang-2), a natural antagonist of angiopoietin-1 (Ang-1) involved in promoting angiogenesis in the presence of ang... | ['Adult', 'Angiopoietin-2', 'Blood Pressure', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Organ Size', 'Placenta', 'Pre-Eclampsia', 'Pregnancy', 'Receptor, TIE-2'] | 16,182,107 | [['M01.060.116'], ['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cost analysis of living donor liver transplantation: the first Italian economical data. | BACKGROUND: Over a period of 30 months, the Niguarda Ca'Granda Hospital performed 12 living donor liver transplants (LDLT) on adult subjects using the split-liver technique and transplant of the right lobe. The purpose of this work is to evaluate the financial obligation that this technique will bring, the ethical and ... | ['Costs and Cost Analysis', 'Hematologic Tests', 'Humans', 'Italy', 'Liver Transplantation', 'Living Donors'] | 17,912,202 | [['N03.219.151'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.898.656']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[IL-2 responsiveness in antigen-specific lymphocyte proliferation test with sulfhydryl drug-sensitized murine lymphocytes--using rapid fluorochromasia assay]. | Response of murine lymphnode cells (LNC) sensitized with sulfhydryl drugs to recombinant interleukin 2 (rIL-2) was studied in antigen-specific lymphocyte proliferation test (LPT). Mice were primed with tiopronin (TP) and gold sodium thiomalate (GTM) and the secondary response to LNC was measured in a proliferative assa... | ['Animals', 'Cell Separation', 'Cross Reactions', 'Drug Hypersensitivity', 'Epitopes', 'Flow Cytometry', 'Interleukin-2', 'Lymphocyte Activation', 'Male', 'Mice', 'Propidium', 'Sulfhydryl Compounds', 'T-Lymphocytes'] | 1,706,443 | [['B01.050'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['G12.122.281'], ['C20.543.206', 'C25.100.468'], ['D23.050.550'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D12.644.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inference on the Genetic Basis of Eye and Skin Color in an Admixed Population via Bayesian Linear Mixed Models. | Genetic association studies in admixed populations are underrepresented in the genomics literature, with a key concern for researchers being the adequate control of spurious associations due to population structure. Linear mixed models (LMMs) are well suited for genome-wide association studies (GWAS) because they accou... | ['Africa, Western', 'Bayes Theorem', 'Color', 'Eye', 'Genetics, Population', 'Genome-Wide Association Study', 'Humans', 'Pigments, Biological', 'Polymorphism, Single Nucleotide', 'Quantitative Trait Loci', 'Skin Pigmentation'] | 28,381,588 | [['Z01.058.290.190'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G01.590.540.199'], ['A01.456.505.420', 'A09.371'], ['H01.158.273.343.335'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.5... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Host-mediated modification of Sau3AI restriction in Listeria monocytogenes: prevalence in epidemic-associated strains. | Most major food-related outbreaks of listeriosis have been traced to a cluster of genetically related strains of serovar 4b (epidemic clone). In spite of numerous searches, distinct bacteriologic or virulence-related features unique to these strains have eluded identification, although a restriction fragment length pol... | ['Adenine', 'Bacteriophages', 'Cloning, Molecular', 'Cytosine', 'DNA Methylation', 'DNA, Bacterial', 'Deoxyribonucleases, Type II Site-Specific', 'Disease Outbreaks', 'Escherichia coli', 'Food Microbiology', 'Listeria monocytogenes', 'Polymorphism, Restriction Fragment Length'] | 9,251,194 | [['D03.633.100.759.138'], ['B04.123'], ['E05.393.220'], ['D03.383.742.698.421'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.444.308.212'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['N06.850.290'], ['B03.440.450.425.325.300', 'B03.660... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Metabolism of pyrazinamide and allopurinol in hereditary xanthine oxidase deficiency. | The metabolism of pyrazinamide and allopurinol was studied in three xanthinuric patients from two families with hereditary xanthinuria to determine whether both substrates were oxidized only by xanthine oxidase or by other oxidases as well. One xanthinuric patient could neither metabolize pyrazinamide into 5-hydroxypyr... | ['Adult', 'Allopurinol', 'Female', 'Humans', 'Male', 'Purine-Pyrimidine Metabolism, Inborn Errors', 'Pyrazinamide', 'Xanthines'] | 2,731,378 | [['M01.060.116'], ['D03.633.100.759.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.798', 'C18.452.648.798'], ['D03.383.679.750'], ['D03.132.960', 'D03.633.100.759.758.824']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Majoon ushba, a polyherbal compound ameliorates rheumatoid arthritis via regulating inflammatory and bone remodeling markers in rats. | The present study was aimed to investigate the anti-arthritic effect of majoon ushba (MU) and its underlying mechanism in adjuvant induced arthritis (AIA) rats. Arthritis was induced by intradermal injection of complete freund's adjuvant (0.1ml) into the right hind paw of the Wistar albino rats. MU (1000mg/kg/b.wt) and... | ['Animals', 'Arthritis, Experimental', 'Arthritis, Rheumatoid', 'Biomarkers', 'Blotting, Western', 'Bone Remodeling', 'Chemokine CCL2', 'Cyclooxygenase 2', 'Cytokines', 'Edema', 'Female', 'Gene Expression', 'Hindlimb', 'Immunohistochemistry', 'Inflammation Mediators', 'Male', 'NF-kappa B', 'Nitric Oxide Synthase Type I... | 26,556,105 | [['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D23.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G11.427.213', 'G16.762.150'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.3... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Presidents and health reform: from Franklin D. Roosevelt to Barack Obama. | The health care reforms that President Barack Obama signed into law in March 2010 were seventy-five years in the making. Since Franklin D. Roosevelt, U.S. presidents have struggled to enact national health care reform; most failed. This article explores the highly charged political landscape in which Obama maneuvered a... | ['Federal Government', 'Health Care Reform', 'History, 20th Century', 'History, 21st Century', 'National Health Insurance, United States', 'Politics', 'Public Opinion', 'United States'] | 20,530,336 | [['I01.409.137', 'I01.409.418.625', 'N03.540.348.500', 'N03.540.400.750'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['K01.400.504.968'], ['K01.400.504.984'], ['N03.219.521.576.343.900', 'N03.349.550.610'], ['I01.738'], ['I01.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Physician glut. Physicians--the next victims of "downsizing?". | Should physicians really be polishing up their CVs or preparing to enter another line of work? In a word: No. What a recent survey makes clear is that, while managed care is driving physicians from some markets, jobs are still available in other markets traditionally underserved by physicians. This is not to suggest th... | ['Consumer Behavior', 'Employment', 'Job Application', 'Personnel Administration, Hospital', 'Physicians', 'United States', 'Vocational Guidance'] | 10,160,035 | [['F01.145.236'], ['N01.824.245'], ['N04.452.677.400'], ['N02.278.216.500.968.565', 'N04.452.442.452.422.565', 'N04.452.677.440'], ['M01.526.485.810', 'N02.360.810'], ['Z01.107.567.875'], ['F02.784.629.937', 'F02.784.692.887']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevention of secondary coxarthrosis in slipped capital femoral epiphysis: a long-term follow-up study after corrective intertrochanteric osteotomy. | Fifty-one patients with unilateral severe (gliding angles 30 degrees-60 degrees) slipped capital femoral epiphysis (SCFE) treated by intertrochanteric corrective osteotomy were reexamined after 20-29 years (average 24 years) of follow-up; 55% of the patients showed neither radiographic signs of degenerative hip disease... | ['Adolescent', 'Adult', 'Child', 'Epiphyses, Slipped', 'Female', 'Femur', 'Follow-Up Studies', 'Humans', 'Male', 'Osteoarthritis, Hip', 'Osteotomy', 'Postoperative Complications'] | 8,866,276 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C05.116.425'], ['A02.835.232.043.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.114.606.400', 'C05.799.613.400'], ['E04.555.580'], ['C23.550.767']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cerebral contusional tears as a marker of child abuse--detection by cranial sonography. | A series of 6 infants subjected to child abuse is presented in whom contusional tears of subcortical white matter were detected during life by intracranial sonography. The sonographic appearances of this highly pathognomonic marker of shaking injury are described for the first time and their significance discussed. On ... | ['Brain Concussion', 'Child Abuse', 'Echoencephalography', 'Female', 'Hematoma, Subdural', 'Humans', 'Infant', 'Male', 'Skull Fractures'] | 1,523,042 | [['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['E01.370.350.578.937.260', 'E01.370.350.700.560.260', 'E01.370.350.850.260', 'E01.370.376.537.750.260', 'E05.629.9... | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Acaricide, fungicide and drug interactions in honey bees (Apis mellifera). | BACKGROUND: Chemical analysis shows that honey bees (Apis mellifera) and hive products contain many pesticides derived from various sources. The most abundant pesticides are acaricides applied by beekeepers to control Varroa destructor. Beekeepers also apply antimicrobial drugs to control bacterial and microsporidial d... | ['Acaricides', 'Animals', 'Anti-Infective Agents', 'Beekeeping', 'Bees', 'Cytochrome P-450 Enzyme System', 'Drug Interactions', 'Fungicides, Industrial', 'Honey', 'Inactivation, Metabolic', 'Nitriles', 'Pesticides', 'Pyrethrins', 'Toluidines', 'Varroidae'] | 23,382,869 | [['D27.720.031.700.071', 'D27.888.723.071'], ['B01.050'], ['D27.505.954.122'], ['J01.040.207'], ['B01.050.500.131.617.720.500.500.875.387'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G07.690.773.968'], ['D27.720.031.700.288', 'D27.888.723.288'], ['G07.203.300.581', 'J02.500.581'], ['G03.171.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of ubiquinone-10 on the stability of biomimetic membranes of relevance for the inner mitochondrial membrane. | Ubiquinone-10 (Q10) plays a pivotal role as electron-carrier in the mitochondrial respiratory chain, and is also well known for its powerful antioxidant properties. Recent findings suggest moreover that Q10 could have an important membrane stabilizing function. In line with this, we showed in a previous study that Q10 ... | ['Adsorption', 'Biomimetic Materials', 'Cell Membrane Permeability', 'Lipid Bilayers', 'Membrane Lipids', 'Mitochondrial Membranes', 'Phosphatidylethanolamines', 'Terpenes', 'Ubiquinone'] | 29,470,946 | [['G01.030', 'G02.020'], ['J01.637.087'], ['G03.143.335', 'G04.175'], ['D10.570.510', 'J01.637.087.500.510'], ['D10.570'], ['A11.284.149.450.349', 'A11.284.835.514.349'], ['D10.570.755.375.760.400.840'], ['D02.455.849'], ['D02.806.250.900', 'D08.211.935']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Molecular heterogeneity of malignant melanomas]. | Malignant melanomas make up a heterogeneous group of tumors characterized by particular genetic aberrations depending on their anatomic localization and UV exposure. Activation of the mitogen-activated protein kinase (MAPK) signaling pathway is found in the majority of melanomas, with either somatic missense mutations ... | ['Cyclin-Dependent Kinase Inhibitor p16', 'Diagnosis, Differential', 'Gene Amplification', 'Genetic Variation', 'Humans', 'Melanoma', 'Phosphatidylinositol 3-Kinases', 'Signal Transduction', 'Skin Neoplasms', 'Tumor Suppressor Protein p14ARF'] | 17,885,757 | [['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['E01.171'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['D08.811.913.696.62... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synergetic effects of caspase 3 and mu-calpain in XIAP-breakdown upon focal cerebral ischemia. | Dysregulation of apoptosis is involved in a wide spectrum of disease ranging from proliferative to neurodegenerative disorders. The recently discovered X-linked inhibitor of apoptosis protein (XIAP) is among the most potent inhibitors of apoptosis. This protein binds to and inhibits both initiator caspases and effector... | ['Animals', 'Apoptosis', 'Blotting, Western', 'Calpain', 'Caspase 3', 'Immunohistochemistry', 'Infarction, Middle Cerebral Artery', 'Ischemic Attack, Transient', 'Laser-Doppler Flowmetry', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Tubulin', 'X-Linked Inhibitor of Apoptosis Protein'] | 17,514,421 | [['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.120', 'D08.811.277.656.300.200.120'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonlinear Connectivity in the Human Stretch Reflex Assessed by Cross-Frequency Phase Coupling. | Communication between neuronal populations is facilitated by synchronization of their oscillatory activity. Although nonlinearity has been observed in the sensorimotor system, its nonlinear connectivity has not been widely investigated yet. This study investigates nonlinear connectivity during the human stretch reflex ... | ['Artifacts', 'Electroencephalography', 'Electromyography', 'Female', 'Humans', 'Male', 'Models, Neurological', 'Motor Activity', 'Motor Cortex', 'Muscle, Skeletal', 'Neural Pathways', 'Nonlinear Dynamics', 'Periodicity', 'Reflex, Stretch', 'Signal Processing, Computer-Assisted', 'Synaptic Transmission', 'Time Factors'... | 27,440,467 | [['E05.047'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['F01.145.632', 'G11.427.410.698'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['A02.633.567', 'A10.690.552.500'], ['A0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
[Investigations on the present status of infections with Chlamydia trachomatis (Ct), Mycoplasma hominis (Mh) and Ureaplasma urealyticum (Uu) in patients with venereal diseases, sexual abusers and healthy people in Da Lian]. | From January to June 1992, we conducted the detection of serum antibodies against Ct, Mh and Uu in patients with venereal diseases, sexual abusers and healthy people. The results showed that the positive rates of antibodies against Ct, Mh and Uu in patients were the highest, while in healthy people those of antibodies ... | ['Adolescent', 'Adult', 'Antibodies, Bacterial', 'Antibodies, Viral', 'China', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Condylomata Acuminata', 'Female', 'Gonorrhea', 'Humans', 'Male', 'Middle Aged', 'Mycoplasma Infections', 'Sexual Partners', 'Superinfection', 'Ureaplasma Infections', 'Ureaplasma urealyticum'... | 7,923,339 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['Z01.252.474.164'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Brain cavernoma: a dynamic lesion. | BACKGROUND: Although the prevalence of brain cavernomas is high (0.50%), for unknown reasons, only a few of them display aggressive clinical behavior.METHODS: From a personal series of 65 operated and histopathologically verified cavernomas, we have conducted a long-term study, both retrospectively and prospectively, o... | ['Adult', 'Atrophy', 'Brain Neoplasms', 'Calcinosis', 'Female', 'Hemangioma, Cavernous', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged'] | 9,400,644 | [['M01.060.116'], ['C23.300.070'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C18.452.174.130'], ['C04.557.645.375.385', 'C14.907.454.385', 'C15.378.463.515.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A fully integrated mixed-signal neural processor for implantable multichannel cortical recording. | A 64-channel neural processor has been developed for use in an implantable neural recording microsystem. In the Scan Mode, the processor is capable of detecting neural spikes by programmable positive, negative, or window thresholding. Spikes are tagged with their associated channel addresses and formed into 18-bit data... | ['Animals', 'Cerebral Cortex', 'Electrodes, Implanted', 'Electroencephalography', 'Equipment Design', 'Equipment Failure Analysis', 'Evoked Potentials', 'Haplorhini', 'Prostheses and Implants', 'Signal Processing, Computer-Assisted', 'Systems Integration', 'Telemetry'] | 17,554,826 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.376.300', 'E01.370.405.245'], ['E05.320'], ['E05.325.192'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400'], ['E07.695'], ['L01.224.800'], ['H01.770.787', 'L01.906.787'], ['E01.370.520.750', 'E05.925... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Thin-film epidural microelectrode arrays for somatosensory and motor cortex mapping in rat. | Assessments of somatosensory and motor cortical somatotopy in vivo can provide important information on sensorimotor physiology. Here, novel polyimide-based thin-film microelectrode arrays (72 contacts) implanted epidurally, were used for recording of somatosensory evoked potentials (SEPs) and somatosensory cortex soma... | ['Action Potentials', 'Animals', 'Brain Mapping', 'Electrodes, Implanted', 'Electrophysiology', 'Epidural Space', 'Evoked Potentials, Somatosensory', 'Forelimb', 'Hindlimb', 'Male', 'Membranes, Artificial', 'Motor Cortex', 'Movement', 'Neurons', 'Neurophysiology', 'Rats', 'Rats, Long-Evans', 'Reaction Time', 'Somatosen... | 18,582,949 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E07.305.250.319', 'E07.695.202'], ['H01.158.344.528', 'H01.158.782.236'], ['A02.835.232.834.803.350'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['A13.395'], ['A13.473'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Cesarean, result of an exploration of a loss of visual acuity]. | Toxaemia of pregnancy associating hypertension and proteinuria can cause maternal and ocular complications. Maternal ocular involvement is classically described with loss of visual acuity due to serous retinal detachment. We report a case of a 31 year old woman who just complained of severe deterioration of visual acui... | ['Adult', 'Cesarean Section', 'Female', 'HELLP Syndrome', 'Humans', 'Pregnancy', 'Visual Acuity'] | 9,745,822 | [['M01.060.116'], ['E04.520.252.500'], ['C13.703.395.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel system for organ and tissues preservation: the refrigerating hyperbaric chamber. | UNLABELLED: This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions.METHODS: The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-... | ['Cold Temperature', 'Equipment Design', 'Hyperbaric Oxygenation', 'Organ Preservation', 'Refrigeration', 'Temperature'] | 16,908,312 | [['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.320'], ['E02.880.690.490'], ['E02.792.833.660', 'E05.760.833.660'], ['E02.792.643', 'E05.760.643'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.1... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Required procedure for nominal data files processing in biomedical research]. | To date, biomedical research using nominal data files for the data collection, data acquisition or data processing has had to comply with 2 French laws (Law of December, 20, 1988, modified, relating to the protection of patients participating in biomedical research, and the Law of January, 6, 1978, completed by the Law... | ['Clinical Trials as Topic', 'Data Collection', 'France', 'Humans', 'Medical Records', 'Research'] | 11,845,106 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['H01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Most highly expressed protein-coding genes have a single dominant isoform. | Although eukaryotic cells express a wide range of alternatively spliced transcripts, it is not clear whether genes tend to express a range of transcripts simultaneously across cells, or produce dominant isoforms in a manner that is either tissue-specific or regardless of tissue. To date, large-scale investigations into... | ['Computational Biology', 'Databases, Protein', 'Humans', 'Open Reading Frames', 'Peptides', 'Protein Isoforms', 'Proteomics'] | 25,732,134 | [['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['D12.644'], ['D12.776.800'], ['H01.158.201.... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The Use of Tissue Glue for Circumcision in Children: Systematic Review and Meta-analysis. | OBJECTIVE: To evaluate the efficacy of tissue glue in pediatric circumcision.MATERIALS AND METHODS: A systematic review and meta-analysis of the English literature (1997-2017) was conducted according to the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) statement on children who underwent ci... | ['Adolescent', 'Child', 'Child, Preschool', 'Circumcision, Male', 'Health Care Costs', 'Hematoma', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Operative Time', 'Postoperative Hemorrhage', 'Surgical Wound Dehiscence', 'Surgical Wound Infection', 'Sutures', 'Tissue Adhesives'] | 29,407,454 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E02.218.085.170', 'E04.085.170', 'E04.950.774.860.226'], ['N03.219.151.400', 'N05.300.375'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['C23.550.414... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Characteristics of prosthetic vision in rats with subretinal flat and pillar electrode arrays. | OBJECTIVE: Retinal prostheses aim to restore sight by electrically stimulating the surviving retinal neurons. In clinical trials of the current retinal implants, prosthetic visual acuity does not exceed 20/550. However, to provide meaningful restoration of central vision in patients blinded by age-related macular degen... | ['Animals', 'Electrodes, Implanted', 'Evoked Potentials, Visual', 'Prosthesis Implantation', 'Rats', 'Rats, Long-Evans', 'Retina', 'Retinal Degeneration', 'Visual Prosthesis'] | 31,341,094 | [['B01.050'], ['E07.305.250.319', 'E07.695.202'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['E04.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['A09.371.729'], ['C11.270.612', 'C11.768.585'], ['E07.695.950']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis. | The expression of metallothionein (MT) in certain tumor cells has been associated with resistance to anticancer drugs. In the present study, we examined the effects of inhibition of MT synthesis on resistance to anticancer drugs of human bladder tumor which were inoculated in nude mice. The results show that pretreatme... | ['Alkynes', 'Animals', 'Cisplatin', 'Colonic Neoplasms', 'Cysteine', 'Doxorubicin', 'Drug Resistance', 'Female', 'Fibrosarcoma', 'Glycine', 'Humans', 'Male', 'Melphalan', 'Metallothionein', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred ICR', 'Mice, Nude', 'Pargyline', 'Sulfates', 'Tumor Cells, Cultured', 'Urinary Bladde... | 7,923,149 | [['D02.455.326.397'], ['B01.050'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D02.455.426.559.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SHORT-TERM OUTCOMES AFTER INTRAVITREAL INJECTIONS OF CONBERCEPT VERSUS RANIBIZUMAB FOR THE TREATMENT OF RETINOPATHY OF PREMATURITY. | PURPOSE: Intravitreal injection of conbercept (IVC) is the latest applied treatment that could be used in retinopathy of prematurity (ROP) patients. The structural outcomes and recurrence of ROP among patients treated with IVC or intravitreal injection of ranibizumab (IVR) were compared.METHODS: A consecutive case seri... | ['Female', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Intravitreal Injections', 'Male', 'Ranibizumab', 'Recombinant Fusion Proteins', 'Recurrence', 'Retinopathy of Prematurity', 'Retrospective Studies'] | 28,699,927 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['E02.319.267.530.475.500'], ['D12.776.124.486.485.114.224.060.868', 'D12.776.124.790.651.114.224.060.868', 'D12.776.377.715.548.114.224.200.868'], ['D12.776.828.300'], ['C23.550.291.937'], ['C11.768.836', 'C16.614.521.731']... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Concealed re-entry in the human heart. | The mechanism and electrophysiologic manifestations of concealed re-entry were studied in human electrocardiograms and intracardiac recordings. Previously described patterns of concealed re-entry were documented in 49 patients. In seven cases concealed re-entry was involved in the genesis of Wenckebach periodicity and ... | ['Arrhythmias, Cardiac', 'Atrioventricular Node', 'Bundle of His', 'Electrocardiography', 'Electrophysiology', 'Heart Conduction System', 'Humans', 'Purkinje Fibers'] | 7,180,359 | [['C14.280.067', 'C23.550.073'], ['A07.541.409.147'], ['A07.541.409.273'], ['E01.370.370.380.240', 'E01.370.405.240'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.409.683']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Antimicrobial and Antioxidant Properties of Satureja Montana L. and S. Subspicata Vis. (Lamiaceae). | Satureja montanaL. and S. subspicata Vis. (Lamiaceae) are used for centuries in traditional medicine of Balcanic people in the healing of the lymphatic nodule and respiratory system inflammation. In this paper the amount of total phenols and flavonoids (analyzed by UV/Vis spectrophotometry), phenolic compounds profile ... | ['Anti-Infective Agents', 'Antioxidants', 'Bacteria', 'Croatia', 'Flavonoids', 'Microbial Sensitivity Tests', 'Phenols', 'Plant Extracts', 'Satureja'] | 25,642,718 | [['D27.505.954.122'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B03'], ['Z01.542.248.295'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.455.426.559.389.657'], ['D20.215.784.500', 'D26.667'], ['B01.650.940.800.575.912... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Placental mosaicism for Trisomy 13: a challenge in providing the cell-free fetal DNA testing. | PURPOSE: We investigated the disagreement between the positive cell-free fetal DNA test for trisomy 13 and the standard cytogenetic diagnosis of one case.METHODS: Cell-free fetal DNA testing was performed by massively parallel sequencing. We used conventional cytogenetic analysis to confirm the commercial cell-free fet... | ['Adult', 'Amniotic Fluid', 'Aneuploidy', 'Chromosome Disorders', 'Chromosomes, Human, Pair 13', 'Cytogenetic Analysis', 'Female', 'Genetic Testing', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Karyotype', 'Mosaicism', 'Placenta', 'Pregnancy', 'Prenatal Diagnosis', 'Trisomy', 'Trisomy 13 Syndrome'] | 24,497,298 | [['M01.060.116'], ['A12.098', 'A16.378.149'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C16.131.260', 'C16.320.180'], ['A11.284.187.520.300.370.375', 'G05.360.162.520.300.370.375'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['E01.370.225.562', 'E05.200.562', 'E05.393.4... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of p16 in serous ovarian neoplasms. | PURPOSE: We aimed to examine p16 protein expression in ovarian serous neoplasms along with normal ovarian tissues.MATERIALS AND METHODS: P16 expression was immunhistochemically evaluated in 86 ovarian serous neoplasms (21 cystadenomas, 20 borderline tumors and 45 carcinomas) and 21 non-neoplastic ovarian tissue. The re... | ['Cyclin-Dependent Kinase Inhibitor p16', 'Cystadenocarcinoma, Serous', 'Female', 'Humans', 'Immunohistochemistry', 'Neoplasm Proteins', 'Ovarian Neoplasms'] | 21,077,476 | [['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.58... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The small for gestational age infant: accelerated or delayed pulmonary maturation? Increased or decreased survival? | OBJECTIVE: Small for gestational age (SGA) neonates have been considered to have accelerated pulmonary maturation and thus a lower risk for respiratory distress syndrome (RDS) than appropriate for gestational age (AGA) neonates. This, however, has not been thoroughly examined. Therefore, we compared SGA infants with AG... | ['Fetal Growth Retardation', 'Fetal Organ Maturity', 'Gestational Age', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Infant, Small for Gestational Age', 'Logistic Models', 'Lung', 'Male', 'Respiratory Distress Syndrome, Newborn', 'Respiratory Insufficiency', 'Risk Factors'] | 7,700,754 | [['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['G07.345.500.325.235.750', 'G07.345.500.325.377.249', 'G08.686.784.170.157.750'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.8... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The analysis of underivatized â-Methylamino-L-alanine (BMAA), BAMA, AEG & 2,4-DAB in Pteropus mariannus mariannus specimens using HILIC-LC-MS/MS. | â-Methylamino-L-alanine (BMAA) has been identified as the potential cause of the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC) observed in the Chamorro people of Guam. The principal hypothesis for BMAA exposure and intoxication relies on the biomagnification of BMAA in flying fox specimens inges... | ['Amino Acids, Diamino', 'Animals', 'Bivalvia', 'Chiroptera', 'Chromatography, Liquid', 'Hair', 'Isomerism', 'Rodentia', 'Skin', 'Tandem Mass Spectrometry'] | 30,102,919 | [['D12.125.095'], ['B01.050'], ['B01.050.500.644.080'], ['B01.050.150.900.649.313.937'], ['E05.196.181.400'], ['A17.360'], ['G02.111.570.685', 'G02.607.445'], ['B01.050.150.900.649.313.992'], ['A17.815'], ['E05.196.566.880']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. | Obstacles to developing an HIV-1 vaccine include extensive viral diversity and lack of correlates of protective immunity. High mutation rates allow HIV-1 to adapt rapidly to selective forces such as antiretroviral therapy and immune pressure, including HIV-1-specific CTLs that select viral variants which escape T-cell ... | ['Adaptation, Physiological', 'China', 'Disease Outbreaks', 'Epitopes, T-Lymphocyte', 'Evolution, Molecular', 'Genetic Variation', 'Genotype', 'HIV Infections', 'HIV Integrase', 'HIV Reverse Transcriptase', 'HIV-1', 'Histocompatibility Antigens Class I', 'Humans', 'Phylogeny', 'Rural Population', 'gag Gene Products, Hu... | 21,562,042 | [['G07.025', 'G16.012.500'], ['Z01.252.474.164'], ['N06.850.290'], ['D23.050.550.402'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['G05.380'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['D08.811.739.500.667.500', 'D08.811.913.696.445.8... | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Phosphoribosylpyrophosphate synthesis from glucose decreases during amino acid starvation of human lymphoblasts. | When cultured human lymphoblasts are starved 3 h for an essential amino acid, rates of purine nucleotide synthesis decrease markedly because of a decrease in the intracellular phosphoribosylpyrophosphate concentration (Boss, G.R., and Erbe, R.W. (1982) J. Biol. Chem. 257, 4242-4247; Boss, G. R. (1984) J. Biol. Chem. 25... | ['Aldose-Ketose Isomerases', 'Amino Acids', 'Biological Transport, Active', 'Carbohydrate Epimerases', 'Cell Line', 'Glucose', 'Humans', 'Lymphocytes', 'Oxidation-Reduction', 'Pentose Phosphate Pathway', 'Pentosephosphates', 'Phosphoribosyl Pyrophosphate', 'Ribulosephosphates'] | 2,581,946 | [['D08.811.399.475.200'], ['D12.125'], ['G03.143.310'], ['D08.811.399.894.500'], ['A11.251.210'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['G02.700', 'G03.295.531'], ['G02.111.158.875', 'G03.191.875', 'G03.295.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of a hyperosmotic agent on epithelial disruptions during laser in situ keratomileusis. | PURPOSE: To evaluate the incidence of epithelial disruptions during primary laser in situ keratomileusis (LASIK) with the use of a preoperative hyperosmotic treatment comprising sodium chloride 5% ophthalmic ointment (Muro-128) and to identify the incidence of epithelial disruptions in various demographic populations.S... | ['Adult', 'Age Factors', 'Corneal Diseases', 'Double-Blind Method', 'Epithelial Cells', 'Epithelium, Corneal', 'Female', 'Humans', 'Intraoperative Complications', 'Keratomileusis, Laser In Situ', 'Lasers, Excimer', 'Male', 'Osmotic Pressure', 'Preoperative Care', 'Prospective Studies', 'Saline Solution, Hypertonic'] | 25,935,340 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C11.204'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A11.436'], ['A09.371.060.217.325', 'A10.272.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['E02.594.480.750', 'E04.014.520.480.750', '... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arterial Calcification Is Regulated Via an miR-204/DNMT3a Regulatory Circuit Both In Vitro and in Female Mice. | Arterial calcification is a common cardiovascular disease that initiates from a process of osteoblastic differentiation of vascular smooth muscle cells (VSMCs). Accumulating evidence has demonstrated that microRNAs play an important role in regulating arterial calcification. miR-204 was significantly downregulated in c... | ['Adult', 'Animals', 'Aorta', 'Case-Control Studies', 'CpG Islands', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Methylation', 'Down-Regulation', 'Female', 'Gene Expression', 'Humans', 'In Vitro Techniques', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Living Donors', 'Male', 'Methylation', 'Mice', 'MicroRNAs... | 29,850,805 | [['M01.060.116'], ['B01.050'], ['A07.015.114.056'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D08.811.913.555.500.350.100.500'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G02.1... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Emotional and behavioral reactions to facially deformed patients before and after craniofacial surgery. | The present experiment investigated whether observers' emotional and behavioral reactions to facially deformed patients could be substantially improved by surgical procedures conducted by well-trained specialists in an experienced multidisciplinary team. Also investigated was the hypothesis that emotional states mediat... | ['Adolescent', 'Adult', 'Attitude to Health', 'Child', 'Child, Preschool', 'Emotions', 'Facial Bones', 'Female', 'Humans', 'Infant', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Random Allocation', 'Skull', 'Social Behavior'] | 3,406,177 | [['M01.060.057'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['M01.060.406.448'], ['F01.470'], ['A02.835.232.781.324'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.401'], ['M01.060.116.630'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.52... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Insights into potential consequences of fusion hypothetical accident, lessons learnt from the former fission accidents. | From previous catastrophic fission nuclear accidents, such as the Chernobyl and Fukushima accidents, researchers learnt the lessons that external hazard beyond design basis or human errors could result in severe accidents and multi-failure of the confinements although they were considered as very-low-probability events... | ['Chernobyl Nuclear Accident', 'Disasters', 'Dose-Response Relationship, Radiation', 'Fukushima Nuclear Accident', 'Humans', 'Power Plants', 'Probability', 'Radiation Monitoring', 'Radioactive Hazard Release'] | 30,513,506 | [['K01.400.504.968.150', 'N06.850.135.848.500'], ['N06.230.100'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['K01.400.504.984.186', 'N06.850.135.848.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.780', 'J03.540.680'], ['E05.318.740.600', 'G17.... | ['Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Reduced polymerization stress of MAPO-containing resin composites with increased curing speed, degree of conversion and mechanical properties. | OBJECTIVES: The degree and rate of photopolymerization in resin-based dental composites will significantly affect polymer network formation and resultant material properties that may determine their clinical success. This study investigates the mechanical properties, the generation of stress from polymerization, tooth ... | ['Composite Resins', 'Curing Lights, Dental', 'Materials Testing', 'Polymerization'] | 24,629,734 | [['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.186.104', 'E07.222.104'], ['E05.570'], ['G02.750']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Adrenocortical responses to corticotropin-releasing factor in the rat. | The time course of plasma corticosterone was measured in male Sprague-Dawley rats whose endogenous release of ACTH had been blocked following rapid i.v. injections of doses ranging from 0.003 to 10 micrograms corticotropin-releasing factor (CRF) per rat and during i.v. infusions at rates ranging from 0.001 to 20 ng CRF... | ['Adrenal Cortex', 'Adrenocorticotropic Hormone', 'Animals', 'Corticosterone', 'Corticotropin-Releasing Hormone', 'Infusions, Parenteral', 'Male', 'Rats', 'Rats, Inbred Strains'] | 3,011,231 | [['A06.300.071.140'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['D06.472.699.327.740.140... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control of normal and transformed cell proliferation by growth factor-nutrient interactions. | The proliferation of normal mammalian cells, similar to that of single bacterial and lower eukaryotic cells, is restricted by space and nutrients. Cultured human lung fibroblasts have been used as a model to show that, in the absence of spatial restrictions, the requirement for specific nutrients limits normal cell pro... | ['Animals', 'Calcium', 'Cell Division', 'Cell Transformation, Neoplastic', 'Cells, Cultured', 'Chick Embryo', 'Culture Media', 'Fibroblasts', 'Growth Substances', 'Hormones', 'Lung', 'Magnesium', 'Neoplasms', 'Phosphates', 'Potassium', 'Pyruvates', 'Pyruvic Acid'] | 6,690,330 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D27.720.470.305', 'E07.206'], ['A11.329.228'], ['D27.505.696.377'], ['D06.472', 'D27.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-time monitoring of electrochemical controlled protein adsorption by a plasmonic nanowire based sensor. | A plasmonic sensor composed of a vertically aligned gold nanowire array was fabricated and employed for the optical detection of protein adsorption induced by an electric field. | ['Adsorption', 'Animals', 'Biosensing Techniques', 'Cattle', 'Electrochemical Techniques', 'Gold', 'Muramidase', 'Nanowires', 'Serum Albumin, Bovine'] | 23,925,550 | [['G01.030', 'G02.020'], ['B01.050'], ['E05.601.043'], ['B01.050.150.900.649.313.500.380.271'], ['E05.301'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D08.811.277.450.642'], ['J01.637.512.925'], ['D12.776.034.841.540', 'D12.776.124.727.875']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Standards to support learning and assessment in practice. | This is the first article in a series of 11 that will offer guidance to new and existing mentors and practice teachers to enable them to develop in their role and help them to gather a portfolio of evidence that meets the Nursing and Midwifery Council's Standards to Support Learning and Assessment in Practice (SSLAP). ... | ['Clinical Competence', 'Competency-Based Education', 'Education, Nursing', 'Humans', 'Learning', 'Mentors', 'Midwifery', 'Students, Nursing', 'United Kingdom'] | 26,967,885 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158.210'], ['I02.358.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['M01.395'], ['H02.478.676.416'], ['M01.848.769.685'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Multiscale Analysis of Neurite Orientation and Spatial Organization in Neuronal Images. | The spatial organization of neurites, the thin processes (i.e., dendrites and axons) that stem from a neuron's soma, conveys structural information required for proper brain function. The alignment, direction and overall geometry of neurites in the brain are subject to continuous remodeling in response to healthy and n... | ['Algorithms', 'Animals', 'Hippocampus', 'Image Processing, Computer-Assisted', 'Male', 'Mice, Inbred C57BL', 'Neurites', 'Reproducibility of Results'] | 27,369,547 | [['G17.035', 'L01.224.050'], ['B01.050'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['L01.224.308'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A08.675.256.500', 'A08.675.542.145.500', 'A11.284.180.610', 'A11.671.501.145.500', 'A11.671.543'], ['E05.318.370.72... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
L-lysine uptake in giant vesicles from cardiac ventricular sarcolemma: two components of cationic amino acid transport. | Cationic L-amino acids enter cardiac-muscle cells through carrier-mediated transport. To study this process in detail, L-[(14)C]lysine uptake experiments were conducted within a 10(3)-fold range of L-lysine concentrations in giant sarcolemmal vesicles prepared from rat cardiac ventricles. Vesicles had a surface-to-volu... | ['Amino Acid Transport Systems, Basic', 'Amino Acids', 'Animals', 'Biological Transport', 'Carbon Radioisotopes', 'Cations', 'Dose-Response Relationship, Drug', 'Ethylmaleimide', 'Heart Ventricles', 'Kinetics', 'Lysine', 'Rats', 'Rats, Sprague-Dawley', 'Sarcolemma'] | 19,032,145 | [['D12.776.157.530.200.374', 'D12.776.543.585.200.374'], ['D12.125'], ['B01.050'], ['G03.143'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D01.248.497.300'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['A07.541.560'], ['G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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