Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Dielectric and calorimetric studies of hydrated purple membrane. | Purple membranes (PM) from halobacteria were hydrated to approximately 0.4 and approximately 0.2 g H(2)O/g of PM and studied by dielectric spectroscopy and differential scanning calorimetry between 120 and 300 K. The dielectric process, attributed to a local (beta) relaxation of the confined supercooled water, shows an... | ['Calorimetry', 'Calorimetry, Differential Scanning', 'Electrophysiology', 'Euryarchaeota', 'Kinetics', 'Lipids', 'Models, Statistical', 'Purple Membrane', 'Spectrum Analysis', 'Temperature', 'Water'] | 16,055,533 | [['E05.196.131'], ['E05.196.131.310', 'E05.196.370.310'], ['H01.158.344.528', 'H01.158.782.236'], ['B02.200'], ['G01.374.661', 'G02.111.490'], ['D10'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['A11.284.149.648', 'A20.871'], ['E05.196.867'], ['G01.906.595', 'G16.500.275.063.725.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Prime Example. A Calif. community's inability to stop a failing not-for-profit hospital from being sold, converted has national implications. | Approval of the sale of a California hospital to a for-profit ended a contentious struggle in the community, where advocates of keeping it not-for-profit worked to stop the sale. The battle highlights the difficulties facing not-for-profits. "Everybody is interested in the best thing for their community and yet because... | ['Bankruptcy', 'California', 'Commerce', 'Community-Institutional Relations', 'Decision Making, Organizational', 'Health Facility Merger', 'Health Services Accessibility', 'Hospitals, Voluntary', 'Poverty', 'Residence Characteristics'] | 17,380,994 | [['N03.219.463.045'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['J01.219'], ['N04.452.822.210'], ['N04.452.190'], ['N02.278.235'], ['N04.590.374.350', 'N05.300.430'], ['N02.278.421.481.800'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['N01.224.791', 'N06.850.505.400.800']] | ['Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Conical polyurethane implants: an uplifting augmentation. | BACKGROUND: Polyurethane-coated conical implants were introduced by Silimed (US distributor: Sientra, Santa Barbara, California) in 2008 and offer an alternative to round or anatomically shaped implants. By their design and volume distribution, they naturally create central volume and give a reasonable fullness to the ... | ['Adult', 'Breast Implantation', 'Breast Implants', 'Female', 'Humans', 'Middle Aged', 'Patient Satisfaction', 'Polyurethanes', 'Prospective Studies', 'Prosthesis Design', 'Reoperation', 'Surveys and Questionnaires', 'Treatment Outcome', 'Young Adult'] | 24,335,014 | [['M01.060.116'], ['E02.218.565.210', 'E04.650.210', 'E04.680.500.210'], ['E07.695.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Quantitative assessment of vasculature with DCE-MRI in nasopharyngeal carcinomas following radiotherapy and its value for efficacy evaluation]. | OBJECTIVE: To study the changes in quantitative kinetic parameters in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) during radiotherapy and their value for efficacy evaluation in patients with nasopharyngeal carcinoma (NPC).METHODS: Twenty-four patients with NPC that had been pathologically confirmed a... | ['Algorithms', 'Capillary Permeability', 'Carcinoma', 'Carcinoma, Squamous Cell', 'Humans', 'Magnetic Resonance Imaging', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Neovascularization, Pathologic', 'Prognosis', 'Treatment Outcome'] | 26,198,942 | [['G17.035', 'L01.224.050'], ['G03.143.330', 'G09.330.165'], ['C04.557.470.200'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.557.470.200.623', 'C04.588.443.665.710.650.500', 'C07.550.350.650.500', 'C07.550.745.650.500', 'C09.647.710.65... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A "housekeeping" gene on the X chromosome encodes a protein similar to ubiquitin. | An X chromosome gene located 40 kilobases downstream from the G6PD gene, at Xq28, was isolated and sequenced. This gene, which we named GdX, spans about 3.5 kilobases of genomic DNA. GdX is a single-copy gene, is conserved in evolution, and has the features of a "housekeeping" gene. At its 5' end, a cluster of CpG dinu... | ['Amino Acid Sequence', 'Base Sequence', 'Chromosome Mapping', 'DNA', 'HeLa Cells', 'Humans', 'Molecular Sequence Data', 'Proteins', 'Sequence Homology, Nucleic Acid', 'Ubiquitins', 'X Chromosome'] | 2,829,204 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['D13.444.308'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.776'], ['G02.111.810.550', 'G05.810.550'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Processing nanoengineered scaffolds through electrospinning and mineralization suitable for biomimetic bone tissue engineering. | Processing scaffolds that mimic the extracellular matrix (ECM) of natural bone in structure and chemical composition is a potential promising option for engineering physiologically functional bone tissue. In this article, we report a novel method, by combining electrospinning and mineralization, to process a series of ... | ['Biomimetic Materials', 'Bone Matrix', 'Bone Substitutes', 'Electrochemistry', 'Materials Testing', 'Nanostructures', 'Nanotechnology', 'Rotation', 'Tissue Engineering'] | 19,627,790 | [['J01.637.087'], ['A10.165.265.166'], ['D25.130.325', 'J01.637.051.130.325'], ['H01.181.529.307'], ['E05.570'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['G01.482.703'], ['E05.481.500.311.500', 'J01.293.069.249.500']] | ['Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Endothelin ETA and ETB receptors in subarachnoid hemorrhage-induced cerebral vasospasm. | The relative roles of endothelin ETA and ETB receptor activation in cerebral vasospasm following subarachnoid hemorrhage were investigated in the rabbit. The endothelin ETA receptor antagonist, BQ610 (1 microM; homopiperidinyl-CO-Leu-D-Trp(CHO)-D-Trp-OH), and the endothelin ETA/ETB receptor antagonist, PD145065 (1 micr... | ['Amino Acid Sequence', 'Animals', 'Ischemic Attack, Transient', 'Molecular Sequence Data', 'Oligopeptides', 'Rabbits', 'Receptors, Endothelin', 'Subarachnoid Hemorrhage'] | 7,957,585 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['L01.453.245.667'], ['D12.644.456'], ['B01.050.150.900.649.313.968.700'], ['D12.776.543.750.695.220', 'D12.776.543.750.750.320'], ['C10.228.140.300.535.800', 'C14.907.253.573.800', 'C23.550.414.913.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Matrix metalloproteinase 2 genotype is associated with nonanastomotic biliary strictures after orthotopic liver transplantation. | BACKGROUND: Nonanastomotic biliary strictures (NAS) are a serious complication after orthotopic liver transplantation (OLT). Matrix metalloproteinases (MMPs) are involved in connective tissue remodelling in chronic liver disease and complications after OLT.AIM: To evaluate the relationship between MMP-2 and MMP-9 gene ... | ['Adolescent', 'Adult', 'Aged', 'Chi-Square Distribution', 'Cholangitis, Sclerosing', 'Cholestasis', 'Constriction, Pathologic', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'Kaplan-Meier Estimate', 'Liver Transplantation', 'Logistic Models', 'Male', 'Matrix Metalloproteinase 2', 'Matrix M... | 21,745,270 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C06.130.120.200.110'], ['C06.130.120.135'], ['C23.300.287'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Urinary biomarkers of oxidative and nitrosative stress and the risk for incident stroke: a nested case-control study from a community-based cohort. | BACKGROUND: Oxidative and nitrosative stress has suggested to be involved in the pathophysiology of cardiovascular diseases, but has unclear relationship with the risk for incident stroke.METHODS: In this nested case-control study, cases consisted of 131 participants who were free of stroke at screening and experienced... | ["8-Hydroxy-2'-Deoxyguanosine", 'Aged', 'Aldehydes', 'Biomarkers', 'Blood Pressure', 'Body Mass Index', 'Cardiovascular Diseases', 'Case-Control Studies', 'Chromatography', 'Creatinine', 'Deoxyguanosine', 'Dinoprost', 'Female', 'Guanine', 'Humans', 'Male', 'Middle Aged', 'Oxidative Stress', 'Predictive Value of Tests',... | 25,675,904 | [['D03.633.100.759.590.454.240.500', 'D13.570.230.360.500', 'D13.570.583.454.240.500'], ['M01.060.116.100'], ['D02.047'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.3... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypohistidinemia in juvenile rheumatoid arthritis. | The mean level of plasma histidine in 86 children with rheumatoid arthritis was found to be significantly lower in comparison with that of controls. The possible influence of various drugs on the plasma histidine concentration is discussed. | ['Adolescent', 'Arthritis, Juvenile', 'Child', 'Child, Preschool', 'Humans'] | 1,258,635 | [['M01.060.057'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multidimensional Prognostic Index in Association with Future Mortality and Number of Hospital Days in a Population-Based Sample of Older Adults: Results of the EU Funded MPI_AGE Project. | BACKGROUND: The Multidimensional Prognostic Index (MPI) has been found to predict mortality in patients with a variety of clinical conditions. We aimed to assess the association of the MPI with future mortality and number of in-hospital days for the first time in a population-based cohort.METHODS: The study population ... | ['Aged', 'Aged, 80 and over', 'Epidemiologic Studies', 'European Union', 'Female', 'Humans', 'Length of Stay', 'Male', 'Models, Statistical', 'Mortality', 'Prognosis', 'Sweden'] | 26,222,546 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500', 'N05.715.360.330.500', 'N06.850.520.450.500'], ['I01.615.500.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. | Uterine receptivity to embryo implantation is coordinately regulated by 17â-estradiol (E(2)) and progesterone (P(4)). Although increased E(2) sensitivity causes infertility, the mechanisms underlying the modulation of E(2) sensitivity are unknown. We show that nuclear receptor coactivator-6 (NCOA6), a reported coactiva... | ['Animals', 'Embryo Implantation', 'Estradiol', 'Female', 'Male', 'Mice', 'Mice, Knockout', 'Nuclear Receptor Coactivators', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Uterus'] | 23,079,602 | [['B01.050'], ['G08.686.784.170.104.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['D12.644.360.024.314', 'D12.776.157.057.080'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A familial study of C5+cholinesterase and its frequency in the normal population. | A case of familial hypercholinesterasemia was presented. A cholinesterase isoenzyme study revealed the extra C5 band nearer to the cathode than C4 on the gradient polyacrylamide gel electrophoresis in 6 out of 8 subjects in the family. No significant difference in the effect of inhibitors and activator was found when c... | ['Cholinesterases', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Gene Frequency', 'Genetic Variation', 'Humans', 'Isoenzymes', 'Male', 'Middle Aged', 'Pedigree'] | 3,220,244 | [['D08.811.277.352.100.170'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.330'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['M01.060.116.630'], ['E05.393.673']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Elimination of Klebsiella pneumoniae NDM from the air and selected surfaces in hospital using radiant catalytic ionization. | Due to increasing antibiotic resistance Klebsiella pneumoniae is a serious threat for the hospitalized patients. The aim of this study was the assessment of radiant catalytic ionization (RCI) efficacy on K. pneumoniae reduction in the air and on selected surfaces. Four K. pneumoniae NDM and ESBLs-producing strains were... | ['Air Microbiology', 'Bacterial Proteins', 'Cross Infection', 'Humans', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Microbial Viability', 'Radiation, Ionizing', 'beta-Lactamases'] | 31,536,642 | [['H01.158.273.540.274.110', 'N06.850.425.110'], ['D12.776.097'], ['C01.248', 'C23.550.291.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.310.503'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['G06.580'], ['G01.750.750'], ['D08.811.277.087.180']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Geriatric psychiatry training: a brief clinical rotation. | Burgeoning interest in geriatric psychiatry has created a challenge of optimally fitting geriatric content into already crowded psychiatric residency curricula. The authors review general considerations in geriatric psychiatry training and describe a brief clinical rotation for working with the elderly. The brief rotat... | ['Aged', 'Community Mental Health Services', 'Curriculum', 'Female', 'Geriatric Psychiatry', 'Humans', 'Internship and Residency', 'Mental Disorders', 'Patient Care Team', 'Physician-Patient Relations', 'United States'] | 7,356,055 | [['M01.060.116.100'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['I02.158'], ['F04.096.544.380', 'H02.403.690.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F03'], ['N04.590.715'], ['F01.829.401.650.675', 'N05.300.660.625'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Household demography and early childhood mortality in a rice-farming village in Northern Laos. | This paper extends Alexandr Chayanov's model of changing household demography (specifically the ratio of food consumers to food producers) and its influence on agricultural behavior so that it includes possible adverse effects of a rising ratio on nutritional status and early childhood mortality within the household. W... | ['Agriculture', 'Child Mortality', 'Child, Preschool', 'Family Characteristics', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Laos', 'Models, Theoretical', 'Monte Carlo Method', 'Nutritional Status', 'Rural Population', 'Socioeconomic Factors'] | 25,775,467 | [['J01.040'], ['E05.318.308.985.550.287', 'N01.224.935.698.150', 'N06.850.505.400.975.550.287', 'N06.850.520.308.985.550.287'], ['M01.060.406.448'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.... | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', '... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Epiglottic hematoma leading to airway obstruction after general anesthesia. | Bleeding into the upper airway can cause airway obstruction and death if not recognized promptly. Anesthesiologists are quite familiar with potential airway obstruction from acute epiglottitis, but they may be less familiar with the potential for airway obstruction from epiglottic hematoma. We report what we believe is... | ['Aged', 'Aged, 80 and over', 'Airway Obstruction', 'Anesthesia, General', 'Anticoagulants', 'Epiglottis', 'Hematoma', 'Humans', 'Laryngeal Diseases', 'Male', 'Postoperative Complications'] | 11,880,019 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.618.846.185'], ['E03.155.197'], ['D27.505.954.502.119'], ['A02.165.257.625.411', 'A02.165.407.500.411', 'A04.329.591.411'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360', 'C09.400'], ['C23.550.767']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Detection of MYCN DNA in the cerebrospinal fluid for diagnosing isolated central nervous system relapse in neuroblastoma. | We present the case of a 1-year-old female with stage-4 neuroblastoma with MYCN amplification; she was treated with five chemotherapy courses, resulting in normalization of elevated serum levels of tumor markers. Complete remission was achieved after allogeneic hematopoietic stem-cell transplantation with reduced-inten... | ['Central Nervous System Neoplasms', 'DNA, Neoplasm', 'Female', 'Humans', 'Infant', 'Magnetic Resonance Imaging', 'N-Myc Proto-Oncogene Protein', 'Neuroblastoma', 'Nuclear Proteins', 'Oncogene Proteins', 'Prognosis'] | 21,370,425 | [['C04.588.614.250', 'C10.551.240'], ['D13.444.308.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.350.825.500'], ['D12.776.260.103.500.625', 'D12.776.260.108.092.625', 'D12.776.624.664.700.158', 'D12.776.930.125.500.563', 'D12.776.930.127.092.625'], ['C04.557.465.625.600.590.650.550'... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A device for long term, in vitro loading of three-dimensional natural and engineered tissues. | In vitro studies of mechanical loads applied to three-dimensional tissue constructs are important to the design and production of functional, engineered bone tissue. This study reports the development and characterization of a mechanical device capable of subjecting a three-dimensional section of natural or engineered ... | ['Animals', 'Bone Marrow Cells', 'Calcium', 'Equipment Design', 'Osteogenesis', 'Phosphorus', 'Rats', 'Stress, Mechanical', 'Tissue Engineering'] | 14,758,925 | [['B01.050'], ['A11.148', 'A15.378.316'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.320'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['D01.268.666'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.374.835'], ['E05.481.500.311.500', 'J01.293.069.249.500']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fate of pesticides during the winemaking process in relation to malolactic fermentation. | The effect of red wine malolactic fermentation on the fate of seven fungicides (carbendazim, chlorothalonil, fenarimol, metalaxyl, oxadixyl, procymidone, and triadimenol) and three insecticides (carbaryl, chlorpyrifos, and dicofol) was investigated. After malolactic fermentation using Oenococcus oeni, which simulated c... | ['Fermentation', 'Food Handling', 'Fungicides, Industrial', 'Insecticides', 'Lactic Acid', 'Leuconostoc', 'Malates', 'Pesticide Residues', 'Wine'] | 15,826,054 | [['G02.111.158.249', 'G03.191.249'], ['J01.576.423.200'], ['D27.720.031.700.288', 'D27.888.723.288'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D02.241.511.459.450'], ['B03.353.750.475.450', 'B03.510.550.475.450'], ['D02.241.081.337.463', 'D02.241.511.505'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.2... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A comparison of genotyping-by-sequencing analysis methods on low-coverage crop datasets shows advantages of a new workflow, GB-eaSy. | BACKGROUND: Genotyping-by-sequencing (GBS), a method to identify genetic variants and quickly genotype samples, reduces genome complexity by using restriction enzymes to divide the genome into fragments whose ends are sequenced on short-read sequencing platforms. While cost-effective, this method produces extensive mis... | ['Crops, Agricultural', 'Genome, Plant', 'Genotype', 'Genotyping Techniques', 'High-Throughput Nucleotide Sequencing', 'Polymorphism, Single Nucleotide', 'Polyploidy', 'Software', 'Soybeans', 'Whole Genome Sequencing', 'Workflow'] | 29,281,959 | [['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['G05.360.340.365'], ['G05.380'], ['E05.393.442'], ['E05.393.760.319'], ['G05.365.795.598'], ['C23.550.210.702', 'G05.365.590.175.677', 'G05.700.740'], ['L01.224.900'], ['B01.650.940.800.575.912.250.401.750'], ['E05.393.760.700.825'], ['L01.906.893']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Lipopolysaccharide perception leads to dynamic alterations in the microtranscriptome of Arabidopsis thaliana cells and leaf tissues. | BACKGROUND: MicroRNAs (miRNAs) are non-coding RNA molecules which have recently emerged as important gene regulators in plants and their gene expression analysis is becoming increasingly important. miRNAs regulate gene expression at the post-transcriptional level by translational repression or target degradation of spe... | ['Arabidopsis', 'Base Sequence', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Lipopolysaccharides', 'MicroRNAs', 'Molecular Sequence Data', 'Plant Cells', 'Plant Leaves', 'Real-Time Polymerase Chain Reaction', 'Sequence Analysis, RNA', 'Transcriptome'] | 25,848,807 | [['B01.650.940.800.575.912.250.157.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.332'], ['G05.308.375'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['L01.453.245.667'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Micronutrient Deficiency Independently Predicts Adverse Health Outcomes in Patients With Heart Failure. | BACKGROUND: Despite growing evidence on the important role of micronutrients in prognosis of heart failure (HF), there has been limited research that micronutrient deficiency predicts health outcomes in patients with HF.PURPOSE: The aim of this study was to determine whether micronutrient deficiency independently predi... | ['Adult', 'Deficiency Diseases', 'Diet, Healthy', 'Dietary Supplements', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Linear Models', 'Male', 'Micronutrients', 'Middle Aged', 'Nutritional Status', 'Risk Factors', 'Surveys and Questionnaires'] | 26,544,174 | [['M01.060.116'], ['C18.654.521.500'], ['F01.829.458.205.500', 'G07.203.650.240.629'], ['G07.203.300.456', 'J02.500.456'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
DNA reassociation kinetics in relation to genome size in four amphibian species. | DNA reassociation kinetics were studied, by means of the hydroxyapatite chromatography method, for four species of Amphibians with different nuclear DNA content: Xenopus laevis (3 pg DNA per haploid genome) and Bufo bufo (7 pg) of the Anura subclass and Triturus cristatus (23 pg) and Necturus maculosus (52 pg) of the U... | ['Amphibians', 'Animals', 'Base Sequence', 'Biological Evolution', 'Bufo bufo', 'DNA', 'Kinetics', 'Molecular Weight', 'Nucleic Acid Renaturation', 'Nucleic Acids', 'Triturus', 'Urodela', 'Xenopus'] | 826,380 | [['B01.050.150.900.090'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['B01.050.150.900.090.180.210.108'], ['D13.444.308'], ['G01.374.661', 'G02.111.490'], ['G02.494'], ['G02.111.619'], ['D13.444'], ['B01.050.150.900.090.608.700.670'], ['B01.050.150.900.090.608'], ['B... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Increased all-terrain vehicle crash accidents in older riders. | OBJECTIVE: Recent reports on all-terrain vehicle (ATV) accidents cite high injury and death rates, disproportionately affecting younger riders. We sought to determine whether serious injuries at a level 1 trauma center have increased among older riders.MATERIALS AND METHODS: Using the trauma registry, 300 ATV accidents... | ['Accidents', 'Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Middle Aged', 'Off-Road Motor Vehicles', 'Protective Clothing', 'Registries', 'Severity of Illness Index', 'Tennessee', 'Trauma Centers', 'Young Adult'] | 19,373,172 | [['N06.850.135'], ['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.937.500.600'], ['E07.700.600', 'J01.637.215.600', 'J0... | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Bilateral first rib fractures associated with driver's air bag inflation: case report and implications for surgery. | A case of bilateral fractures of the first rib occurring in an otherwise fit road traffic accident victim is described. The only other injuries sustained were of the peripheral limbs. The driver's air bag was inflated during the crash, leading to speculation as to whether this may have contributed to the mechanism of i... | ['Accidents, Traffic', 'Adult', 'Air Bags', 'Angiography', 'Craniocerebral Trauma', 'Disease-Free Survival', 'Fractures, Bone', 'Hand Injuries', 'Humans', 'Leg Injuries', 'Male', 'Multiple Trauma', 'Rib Fractures'] | 9,422,183 | [['N06.850.135.392'], ['M01.060.116'], ['E07.700.100', 'J01.637.708.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C10.900.300', 'C26.915.300'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C26.404'], ... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Ridge sowing of sunflower (Helianthus annuus L.) in a minimum till system improves the productivity, oil quality, and profitability on a sandy loam soil under an arid climate. | Sunflower (Helianthus annuus L.) is a major oilseed crop grown for its edible oil across the globe including Pakistan. In Pakistan, the production of edible oil is less than the required quantity; the situation is being worsened with the increasing population. Thus, there is dire need to grow those sunflower genotypes ... | ['Desert Climate', 'Fatty Acids', 'Helianthus', 'Pakistan', 'Plant Leaves', 'Seeds', 'Soil', 'Sunflower Oil'] | 29,446,028 | [['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['D10.251'], ['B01.650.940.800.575.912.250.100.400'], ['Z01.252.245.723'], ['A18.024.812'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D20.215.784.750.910']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Surgical treatment of squamous cell carcinoma of the oesophagus. | During the period 1976-1983, a total of 72 patients with squamous cell carcinoma of the oesophagus were seen. Exploration was undertaken in 62 patients and all those explored had their tumours resected. The overall operative mortality rate was 12.9 per cent. Overall survival rates were 49 per cent at 1 year, 31 per cen... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Time Factors'] | 6,487,971 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines. | UNLABELLED: The role of tumor necrosis factor alpha, interleukin 6, leptin, and adiponectin in the pathogenesis of hepatitis C virus (HCV)-associated insulin resistance (IR) remains controversial. We tested the hypothesis that these adipocytokines contribute to chronic HCV-associated IR and liver injury by first compar... | ['Adiponectin', 'Adult', 'Biopsy', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Insulin Resistance', 'Interleukin-6', 'Leptin', 'Liver', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Patient Selection', 'Reference Values', 'Tumor Necrosis Factor-alpha', 'Viral Load'] | 17,596,870 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Excitation-Contraction Coupling Time is More Sensitive in Evaluating Cardiac Systolic Function. | Background: Pressure overload-induced myocardial hypertrophy is a key step leading to heart failure. Previous cellular and animal studies demonstrated that deteriorated excitation-contraction coupling occurs as early as the compensated stage of hypertrophy before the global decrease in left ventricular ejection fractio... | ['Adult', 'Echocardiography', 'Echocardiography, Doppler', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Systole', 'Ventricular Function, Left'] | 30,058,581 | [['M01.060.116'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The failure of morphine to attenuate spinal cord nociceptive transmission through supraspinal actions in the cat. | Morphine sulphate was perfused between the third ventricle and cisterna magna in alpha-chloralose anaesthetized cats while recording from multireceptive dorsal horn neurones activated by peripheral noxious radiant heat. Morphine concentrations of 10(-5) and 10(-4) M were without effect, while 10(-3) M resulted in an in... | ['Animals', 'Cats', 'Female', 'Hot Temperature', 'Injections, Intraventricular', 'Male', 'Morphine', 'Nociceptors', 'Spinal Cord', 'Synaptic Transmission'] | 3,013,718 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['E02.319.267.530.550'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Medicinal plants for the treatment of urogenital tract pathologies according to Dioscorides' De Materia Medica. | The De Materia Medica of the Greek Dioscorides reports about 200 plants used for the treatment of pathologies of the urogenital tract during the 1st century AD. On the basis of explicit and implicit affirmations by Dioscorides, a theoretical system concerning the specific properties of these plants has been attempted. ... | ['Female Urogenital Diseases', 'Greek World', 'History, Ancient', 'Humans', 'Male Urogenital Diseases', 'Phytotherapy', 'Plants, Medicinal'] | 9,189,241 | [['C13.351'], ['I01.076.201.450.226.800.250'], ['K01.400.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12'], ['E02.190.755'], ['B01.650.560']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Inhibitory effect of natural organic matter or other background constituents on photocatalytic advanced oxidation processes: Mechanistic model development and validation. | The ability of reactive oxygen species (ROS) to interact with priority pollutants is crucial for efficient water treatment by photocatalytic advanced oxidation processes (AOPs). However, background compounds in water such as natural organic matter (NOM) can significantly hinder targeted reactions and removal efficiency... | ['Catalysis', 'Hydrogen Peroxide', 'Oxidation-Reduction', 'Photolysis', 'Reactive Oxygen Species', 'Water Pollutants, Chemical'] | 26,302,091 | [['G02.130'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02.700', 'G03.295.531'], ['G02.740.685'], ['D01.339.431', 'D01.650.775'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative studies on the stereo architecture of the connective tissue papillae in some mammalian tongues. | The epithelial cell layer was removed from the underlying connective tissue papillae by the method of long term hydrochloric acid treatment and the connective tissue surface was observed by scanning electron microscopy. Tongues of insectivora (Suncus murinus), rodentia (mouse, rat, guinea pig), carnivores (dog, cat) an... | ['Animals', 'Cats', 'Connective Tissue', 'Dogs', 'Epithelium', 'Guinea Pigs', 'Humans', 'Mice', 'Microscopy, Electron, Scanning', 'Rats', 'Species Specificity', 'Tongue'] | 2,748,642 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A10.165'], ['B01.050.150.900.649.313.750.250.216.200'], ['A10.272'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the importance of accounting for competing risks in pediatric cancer trials designed to delay or avoid radiotherapy: I. Basic concepts and first analyses. | PURPOSE: In trials designed to delay or avoid irradiation among children with malignant brain tumor, although irradiation after disease progression is an important event, patients who have disease progression may decline radiotherapy (RT), or those without disease progression may opt for elective RT. To accurately desc... | ['Algorithms', 'Antineoplastic Agents', 'Brain Neoplasms', 'Child, Preschool', 'Disease Progression', 'Disease-Free Survival', 'Ependymoma', 'Humans', 'Kaplan-Meier Estimate', 'Linear Models', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Neoplasms, Second Primary', 'Probability', 'Risk Assessment', 'Time Facto... | 19,577,860 | [['G17.035', 'L01.224.050'], ['D27.505.954.248'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406.448'], ['C23.550.291.656'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C04.557... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes. | Increased production of advanced glycosylation end products (AGEs) and augmented oxidative stress may contribute to vascular complications in diabetes. Little is known about the formation and accumulation of AGEs in young patients with type 1 diabetes. The aim of the present study was to investigate whether AGE product... | ["8-Hydroxy-2'-Deoxyguanosine", 'Acrolein', 'Adolescent', 'Adult', 'Arginine', 'Child', 'Child, Preschool', 'Creatinine', 'Deoxyguanosine', 'Diabetes Mellitus, Type 1', 'Female', 'Glycation End Products, Advanced', 'Humans', 'Lysine', 'Male', 'Norleucine', 'Oxidative Stress', 'Pyrroles', 'Regression Analysis'] | 12,761,359 | [['D03.633.100.759.590.454.240.500', 'D13.570.230.360.500', 'D13.570.583.454.240.500'], ['D02.047.122'], ['M01.060.057'], ['M01.060.116'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['M01.060.406'], ['M01.060.406.448'], ['D03.383.129.308.207'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Detecting DNA damage of cell in rats using comet assay after tetramine poisoned]. | OBJECTIVE: To study the damage of DNA in lymphocytes, brain cells and cardiac muscle cells of rats induced by different dose of tetramine and to speculate the toxicant mechanism of tetramine.METHODS: The rat were poisoned by Tetramine, which was taken in by mouth. The rat poisoning models were used by 0.2, 0.1, 0.05, 0... | ['Animals', 'Brain', 'Bridged-Ring Compounds', 'Comet Assay', 'DNA Damage', 'Dose-Response Relationship, Drug', 'Electrophoresis, Agar Gel', 'Lymphocytes', 'Myocardium', 'Rats', 'Rats, Sprague-Dawley'] | 15,895,805 | [['B01.050'], ['A08.186.211'], ['D02.455.426.100', 'D04.075'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.196.401.153', 'E05.301.300.100'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['A... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial RNA editing truncates a chimeric open reading frame associated with S male-sterility in maize. | Adjacent mitochondrial open reading frames orf355 and orf77 are associated with S cytoplasmic male sterility (CMS-S) in maize, but the mechanisms leading to collapse of developing CMS-S pollen are unknown. Sequence similarity between orf77 and the mitochondrial ATP synthase subunit 9 (atp9) locus led us to examine RNA ... | ['Amino Acid Sequence', 'Arabidopsis Proteins', 'Base Sequence', 'Fertility', 'Mitochondria', 'Mitochondrial Proton-Translocating ATPases', 'Molecular Sequence Data', 'Open Reading Frames', 'Plant Proteins', 'Proteolipids', 'RNA Editing', 'Recombinant Proteins', 'Zea mays'] | 12,491,012 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G08.686.210'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D08.811.277.040.025.325.750', 'D08.811.913.696.650.150.500.750', 'D12.776.157.530.450.250.875.500.750', 'D12.776.543.585.450... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Tissue-Specific Profiling of Oxidative Stress-Associated Transcriptome in a Healthy Mouse Model. | Oxidative stress is a common phenomenon and is linked to a wide range of diseases and pathological processes including aging. Tissue-specific variation in redox signaling and cellular responses to oxidative stress may be associated with vulnerability especially to age-related and chronic diseases. In order to provide a... | ['Animals', 'Computational Biology', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Gene Ontology', 'Male', 'Mice', 'Organ Specificity', 'Oxidative Stress', 'Reactive Oxygen Species', 'Transcriptome'] | 30,326,626 | [['B01.050'], ['H01.158.273.180', 'L01.313.124'], ['E05.393.332'], ['G05.308'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['G07.650'], ['G03.673', 'G07.775.750'], ['D01... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Inhibition of Pancreatic Lipase and Triacylglycerol Intestinal Absorption by a Pinh?o Coat (Araucaria angustifolia) Extract Rich in Condensed Tannin. | The purpose of the present work was to characterize the possible inhibition of pancreatic lipase by a tannin-rich extract obtained from the pinh?o (Araucaria angustifolia seed) coat, based on the previous observation that this preparation inhibits á-amylases. Kinetic measurements of pancreatic lipase revealed that the ... | ['Animals', 'Lactones', 'Lipase', 'Magnoliopsida', 'Male', 'Mice', 'Olive Oil', 'Orlistat', 'Pancreas', 'Plant Extracts', 'Proanthocyanidins', 'Seeds', 'Triglycerides'] | 26,184,295 | [['B01.050'], ['D02.540'], ['D08.811.277.352.100.400'], ['B01.650.940.800.575.912.250'], ['B01.050.150.900.649.313.992.635.505.500'], ['D10.212.302.380.580', 'D10.212.507.650', 'D10.627.700.728', 'G07.203.300.375.400.500', 'J02.500.375.400.500'], ['D02.540.529'], ['A03.734'], ['D20.215.784.500', 'D26.667'], ['D03.383.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Affinity of hepatic glucocorticoid receptors is influenced by energy/feeding status. | Genetically obese animals have been shown to have a reduced number and affinity of glucocorticoid receptors. The relationship between the alterations in receptor binding and the regulation of energy balance is not known. We sought to determine the role of body energy/feeding status on the binding characteristics of glu... | ['Adrenalectomy', 'Animals', 'Corticosterone', 'Dexamethasone', 'Energy Metabolism', 'Feeding Behavior', 'Food Deprivation', 'Liver', 'Male', 'Radioligand Assay', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Glucocorticoid', 'Weight Loss'] | 8,295,956 | [['E04.270.115'], ['B01.050'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G03.295'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.658.433'], ['A03.620'], ['E01.370.225.985', 'E01.370.374.650', 'E01.370.384.720', 'E05.200.985'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minimally disruptive optical control of protein tyrosine phosphatase 1B. | Protein tyrosine phosphatases regulate a myriad of essential subcellular signaling events, yet they remain difficult to study in their native biophysical context. Here we develop a minimally disruptive optical approach to control protein tyrosine phosphatase 1B (PTP1B)-an important regulator of receptor tyrosine kinase... | ['Allosteric Regulation', 'Animals', 'Biosensing Techniques', 'COS Cells', 'Chlorocebus aethiops', 'Crystallography, X-Ray', 'Fluorescence Resonance Energy Transfer', 'HEK293 Cells', 'Humans', 'Optogenetics', 'Phosphorylation', 'Phototropins', 'Protein Tyrosine Phosphatase, Non-Receptor Type 1', 'Receptor, Insulin', 'R... | 32,034,150 | [['G02.111.044'], ['B01.050'], ['E05.601.043'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.196.309.742.225'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-fertility in cows with an abnormal indole metabolism and disturbed carbohydrate composition in the cervical mucus: a preliminary report. | Cervical mucus samples of the cow appear to provide information on the probability of becoming pregnant. In six 'repeat breeders' a strong indole metabolism was found in the cervix. When luteal tissue was decreasing and follicles increasing, compounds were found indicating possible exfoliation of the endometrium, which... | ['Animals', 'Carbohydrates', 'Cattle', 'Cattle Diseases', 'Cervix Mucus', 'Endometrium', 'Estrus', 'Female', 'Glucuronates', 'Glucuronic Acid', 'Gonadotropins, Equine', 'Indoles', 'Infertility, Female', 'Insemination', 'Ovulation', 'Pregnancy', 'Progesterone', 'Prostaglandins F'] | 6,889,949 | [['B01.050'], ['D09'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A12.200.503.339'], ['A05.360.319.679.490'], ['G08.686.195.500'], ['D02.241.081.844.915.162', 'D02.241.152.811.162', 'D02.241.511.902.915.162', 'D09.811.922.162'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.91... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patients' experiences of the PICC insertion procedure. | Peripherally inserted central catheters (PICCs) are a type of central venous access device used to deliver a variety of intravenous therapies, including chemotherapy. PICCs may be placed by interventional radiologists, anaesthetists or, as is increasingly common, by specialist nurses in the hospital setting. However, l... | ['Adaptation, Psychological', 'Antineoplastic Agents', 'Anxiety', 'Catheterization, Central Venous', 'Catheterization, Peripheral', 'Humans', 'Neoplasms', 'Pain', 'Patient Satisfaction', 'Pilot Projects', 'Radiology, Interventional'] | 24,261,003 | [['F01.058'], ['D27.505.954.248'], ['F01.470.132'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['F... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The Faith Community and the SARS-CoV-2 Outbreak: Part of the Problem or Part of the Solution? | The current outbreak of the SARS-CoV-2 virus is a critical moment in time for institutional religion in the USA and throughout the world. Individual clergy and congregations, across faith traditions, have been sources of misinformation and disinformation, promoting messages and actions that engender fear, animosity tow... | ['Betacoronavirus', 'COVID-19', 'Clergy', 'Coronavirus Infections', 'Disease Outbreaks', 'Humans', 'Pandemics', 'Pneumonia, Viral', 'Population Health', 'SARS-CoV-2'] | 32,488,827 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['M01.526.799.500'], ['C01.925.782.600.550.200'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.290.200.6... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of past noninjection drug abuse upon executive function and working memory in HIV infection. | Interactive effects of past noninjection drug abuse/dependence and HIV disease status upon measures of executive function were assessed in a group of 294 homosexual men. Participants were stratified according to HIV status and substance use diagnoses, thereby yielding a 4 (seronegative, asymptomatic seropositive, sympt... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Analysis of Variance', 'CD4-Positive T-Lymphocytes', 'Demography', 'HIV Infections', 'HIV Seronegativity', 'HIV Seropositivity', 'Homosexuality, Male', 'Humans', 'Male', 'Memory, Short-Term', 'Neuropsychological Tests', 'Problem Solving', 'Psychomotor Performance', 'Subs... | 13,680,438 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', '... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
High prevalence of blaCTX-M in Enterobacteriaceae isolates from the Kingdom of Bahrain. | OBJECTIVE: To determine the molecular epidemiology of extended-spectrum â-lactamase (ESBL) by testing a cohort of clinical ESBL-producing bacterial isolates that were isolated in the Kingdom of Bahrain.METHODS: ESBL producing Enterobacteriaceae isolates (based on phenotypic tests) were collected from Microbiology Labor... | ['Anti-Bacterial Agents', 'Bahrain', 'Cohort Studies', 'Community-Acquired Infections', 'Drug Resistance, Bacterial', 'Escherichia coli', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Female', 'Humans', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Male', 'Microbial Sensitivity Tests', 'Prevalence',... | 22,118,027 | [['D27.505.954.122.085'], ['Z01.252.245.500.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.234'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['D12.776.097.275'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Quantitative structure activity analysis of 2-alkoxydihydrocinnamates as PPARalpha/gamma dual agonist. | To optimize the physiochemical properties of 2-alkoxydihydrocinnamates as PPARalpha/gamma dual agonist, a quantitative structure activity relationship, Hansch approach was made using combination of various thermodynamic, electronic and spatial descriptors. Several regression expressions are obtained using multiple line... | ['Cinnamates', 'Linear Models', 'PPAR alpha', 'PPAR gamma', 'Quantitative Structure-Activity Relationship', 'Thermodynamics'] | 18,473,920 | [['D02.241.223.200'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['D12.776.826.239.500'], ['D12.776.826.239.588'], ['G02.111.830.500', 'G07.690.773.997.500'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Regulation of bovine adrenal cell corticotropin receptor mRNA levels by corticotropin (ACTH) and angiotensin-II (A-II). | Bovine adrenal fasciculata-reticularis cells (BAC) expressed at least four ACTH receptor (ACTH-R) mRNA transcripts, one major of 3.6 kb and three minor of 4.2, 1.8 and 1.3 kb. ACTH and A-II increased ACTH-R mRNA levels in a time- and dose-dependent manner. At maximal concentrations, ACTH caused a 2.7-fold increase in t... | ['Adrenocorticotropic Hormone', 'Angiotensin II', 'Animals', 'Cattle', 'Cells, Cultured', 'Dactinomycin', 'Gene Expression Regulation', 'Kinetics', 'RNA, Messenger', 'Receptors, Corticotropin', 'Zona Fasciculata'] | 7,958,385 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Erythromycin resistant mutations in Bacillus subtilis cause temperature sensitive sporulation. | All of several hundred erythromycin resistant single site mutants of Bacillus subtilis W168 are temperature senstive for sporulation. The mutants and wild type cells grow vegetatively at essentially the same rates at both permissive (30 degrees C) and nonpermissive (47 degrees C) temperatures. In addition cellular prot... | ['Bacillus subtilis', 'Drug Resistance, Microbial', 'Erythromycin', 'Hot Temperature', 'Mutation', 'Phenotype', 'Protein Biosynthesis', 'Ribosomes', 'Spores'] | 402,547 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['G06.225', 'G07.690.773.984.269'], ['D02.540.576.500.992'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of selective cyclooxygenase isoform inhibition on systemic prostacyclin synthesis and on platelet function at rest and after exercise in healthy volunteers. | To test the hypothesis that selective inhibition of cyclooxygenase (COX)-2 would result in exercise-induced platelet activation by causing a shift in the endogenous thromboxane (TX)/prostacyclin balance, a double blind, randomized study comparing aspirin (300 mg/d) with rofecoxib (25 mg/d) (cross-over design, 14 days w... | ['Adenosine Diphosphate', 'Adult', 'Aspirin', 'Atherosclerosis', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Double-Blind Method', 'Endothelium', 'Epoprostenol', 'Exercise', 'Humans', 'Isoenzymes', 'Lactones', 'Male', 'Platelet Activation', 'Rest', 'Risk Factors', 'Sulfones', 'Thrombosis', '... | 17,654,308 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.116'], ['D02.455.426.559.389.657.410.595.176'], ['C14.907.137.126.307'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Determination of Lead in Water Samples Using a New Vortex-Assisted, Surfactant-Enhanced Emulsification Liquid-Liquid Microextraction Combined with Graphite Furnace Atomic Absorption Spectrometry. | A low toxic solvent-based vortex-assisted surfactant-enhanced emulsification liquid-liquid microextraction (LT-VSLLME) combined with graphite furnace atomic absorption spectrometry was developed for the extraction and determination of lead (Pb) in water samples. In the LT-VSLLME method, the extraction solvent was dispe... | ['Calibration', 'Chelating Agents', 'Environmental Monitoring', 'Graphite', 'Lead', 'Limit of Detection', 'Liquid Phase Microextraction', 'Spectrophotometry, Atomic', 'Surface-Active Agents', 'Water Pollutants, Chemical'] | 26,614,355 | [['E05.978.155'], ['D27.505.519.914.500', 'D27.720.832.500'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.268.150.300', 'D01.578.300'], ['D01.268.556.435', 'D01.552.544.435'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.196.155.650.500'], ['E05.196.712.726.551', 'E05.196.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
NS-398, a selective COX-2 inhibitor, inhibits proliferation of IL-1beta-stimulated vascular smooth muscle cells by induction of HO-1. | We investigated whether NS-398, a selective inhibitor of COX-2, induces HO-1 in IL-1beta-stimulated vascular smooth muscle cells (VSMC). NS-398 reduced the production of PGE(2) without modulation of expression of COX-2 in IL-1beta-stimulated VSMC. NS-398 increased HO-1 mRNA and protein in a dose-dependent manner, but i... | ['Animals', 'Cell Proliferation', 'Cells, Cultured', 'Cyclooxygenase 2 Inhibitors', 'Dinoprostone', 'Heme Oxygenase-1', 'Interleukin-1beta', 'Male', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Nitrobenzenes', 'Rats', 'Rats, Sprague-Dawley', 'Sulfonamides'] | 18,809,379 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D08.811.682.690.708.410.500'], ['D12.644.276.374.465.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First report of a bite by the mottled rock rattlesnake (Crotalus lepidus lepidus). | Bites by the mottled rock rattlesnake (Crotalus lepidus lepidus) are rare. There appear to be no reports of bites by this subspecies in the literature. This is a case report of a bite by a captive specimen of this diminutive pit viper, and includes a review of what is known regarding its venom. | ['Adult', 'Animals', 'Crotalid Venoms', 'Crotalus', 'Hematologic Tests', 'Humans', 'Male', 'Snake Bites', 'Texas'] | 16,051,298 | [['M01.060.116'], ['B01.050'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['B01.050.150.900.833.672.125.937.240.500'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.723.127.442', 'C26.176.724'], ['Z01.107.567.875.760.750']] | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
A multimodal regional intervention strategy framed as friendly competition to improve hand hygiene compliance. | OBJECTIVE: To investigate the effects of friendly competition on hand hygiene compliance as part of a multimodal intervention program.DESIGN: Prospective observational study in which the primary outcome was hand hygiene compliance. Differences were analyzed using the Pearson ÷2 test. Odds ratios (ORs) with 95% confiden... | ['Cross Infection', 'Guideline Adherence', 'Hand Disinfection', 'Health Personnel', 'Health Promotion', 'Hospital Units', 'Hospitals', 'Humans', 'Logistic Models', 'Multilevel Analysis', 'Netherlands', 'Prospective Studies'] | 30,698,134 | [['C01.248', 'C23.550.291.875.500'], ['N04.761.337', 'N05.715.360.395'], ['N06.850.670.150.500'], ['M01.526.485', 'N02.360'], ['I02.233.332.445', 'N02.421.726.407.579'], ['N02.278.388'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750... | ['Diseases [C]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Modified model for the switch from Sendai virus transcription to replication. | RNase mapping was used to estimate the levels of unencapsidated Sendai virus plus-strand RNAs which cross the leader-NP junction relative to NP mRNA. Significant amounts of leader readthrough RNAs were found in Z strain-infected cells, similar to that described for the polR mutant of vesicular stomatitis virus, even th... | ['Cell Line', 'DNA-Directed RNA Polymerases', 'Gene Expression Regulation', 'Genes, Viral', 'In Vitro Techniques', 'Nucleocapsid Proteins', 'Nucleoproteins', 'Parainfluenza Virus 1, Human', 'RNA Probes', 'RNA, Viral', 'Transcription, Genetic', 'Viral Core Proteins', 'Virus Replication'] | 2,539,496 | [['A11.251.210'], ['D08.811.913.696.445.735.270'], ['G05.308'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['E05.481'], ['D12.776.964.970.600'], ['D12.776.664'], ['B04.820.480.937.600.650.700.715'], ['D13.444.600.723', 'D27.505.259.750.600.825', 'D27.720.470.530.600.825'], ['... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Value of postoperative radiation therapy for regional control after dissection in head and neck squamous cell carcinoma cases. | OBJECTIVE: We aimed to define clinicopathologic risk factors associated with regional recurrence (RR) and thus the effectiveness of postoperative radiotherapy (PORT) for neck control for head and neck squamous cell carcinomas (HNSCCs) with differing cervical lymph node status.METHODS: A retrospective study was performe... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Female', 'Follow-Up Studies', 'Head and Neck Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neck Dissection', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Postoperative ... | 23,991,989 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prostate-specific antigen nadir and cancer-specific mortality following hormonal therapy for prostate-specific antigen failure. | PURPOSE: For men receiving androgen-suppression therapy (AST) for a rising postoperative or postradiation prostate-specific antigen (PSA), we evaluated whether a PSA nadir of more than 0.2 ng/mL was significantly associated with prostate cancer-specific mortality (PCSM).PATIENTS AND METHODS: The study cohort comprised ... | ['Aged', 'Aged, 80 and over', 'Androgen Antagonists', 'Antineoplastic Agents, Hormonal', 'Biomarkers, Tumor', 'Cohort Studies', 'Evaluation Studies as Topic', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prognosis', 'Proportional Hazards Models', 'Prostate-Specific Antigen', 'Pros... | 16,170,163 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D06.347.065', 'D27.505.696.399.450.065'], ['D27.505.954.248.169'], ['D23.101.140'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.337', 'N05.715.360.335'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improving cancer pain management through patient and family education. | The purpose of this study was to determine if continued access to information following a baseline pain education program would increase knowledge and positive beliefs about cancer pain management, thus resulting in improved pain control during a 6-month follow-up period. Patients with cancer-related pain and their pri... | ['Family', 'Follow-Up Studies', 'Humans', 'Neoplasms', 'Outcome Assessment, Health Care', 'Pain', 'Pain Management', 'Patient Education as Topic'] | 12,691,686 | [['F01.829.263', 'I01.880.853.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.74... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
What's in a kiss? The effect of romantic kissing on mating desirability. | Past research suggests that various courtship rituals, such as romantic kissing, may convey useful mate quality information. Two studies were carried out to examine how purported romantic kissing abilities, as a potential cue to some form of mate information, affect appraisals of potential mating partners. In Experimen... | ['Adolescent', 'Adult', 'Choice Behavior', 'Courtship', 'Cues', 'Female', 'Humans', 'Male', 'Men', 'Middle Aged', 'Photic Stimulation', 'Sexual Partners', 'Surveys and Questionnaires', 'United Kingdom', 'United States', 'Women', 'Young Adult'] | 25,299,759 | [['M01.060.057'], ['M01.060.116'], ['F02.463.785.373.346'], ['F01.145.802.279'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.390'], ['M01.060.116.630'], ['E05.723.729'], ['M01.778'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.542.363'], ['Z01.107.567.875'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis. | INTRODUCTION: Animal models of thrombosis and hemostasis are critical for target validation in pharmaceutical research. Guinea pig haemostatic mechanisms, such as the platelet thrombin receptor repertoire, resemble those of humans. Measuring the performance characteristics of marketed antithrombotic drugs in guinea pig... | ['Animals', 'Anticoagulants', 'Arginine', 'Arteriovenous Shunt, Surgical', 'Aspirin', 'Bleeding Time', 'Chlorides', 'Ferric Compounds', 'Guinea Pigs', 'Hemostasis', 'Male', 'Pipecolic Acids', 'Platelet Aggregation Inhibitors', 'Sulfonamides', 'Thrombosis', 'Tirofiban', 'Tyrosine'] | 18,479,740 | [['B01.050'], ['D27.505.954.502.119'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E04.035.087', 'E04.100.814.868.249'], ['D02.455.426.559.389.657.410.595.176'], ['E01.370.225.625.625.100', 'E05.200.625.625.100', 'G09.188.087'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D01.490.100'], ['B01.050.150... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Computed Tomography Angiography Evaluation of Risk Factors for Unstable Intracranial Aneurysms. | OBJECTIVE: To evaluate risk factors for instability in intracranial aneurysms (IAs) using computed tomography angiography (CTA).METHODS: A total of 614 consecutive patients diagnosed with 661 IAs between August 2011 and February 2016 were reviewed. Patients and IAs were divided into stable and unstable groups. Along wi... | ['Adult', 'Aged', 'Computed Tomography Angiography', 'Female', 'Follow-Up Studies', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'ROC Curve', 'Retrospective Studies', 'Risk Factors'] | 29,567,291 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Correlation between the inferior vena cava collapsibility and asymptomatic pericardial effusion in hemodialysis patients]. | INTRODUCTION: The inferior vena cava collapsibility index is a sign of hypervolemia in hemodialysis patients. Asymptomatic pericardial effusion in these patients can be either a sign of hypervolemia or bad systolic function of the left ventricle, or both. The aim of this study was to assess the incidence of asymptomati... | ['Blood Volume', 'Echocardiography', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Pericardial Effusion', 'Renal Dialysis', 'Vena Cava, Inferior'] | 18,928,186 | [['G09.188.130', 'G09.330.380.092'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['C14.280.695'], ['E02.870.300', 'E02.912.800'], ['A07.015.908.949.648']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Food patterns and socioeconomic indicators of food consumption amongst Inuvialuit in the Canadian Arctic. | BACKGROUND: Inuvialuit in the Canadian Arctic have been experiencing a nutrition transition resulting in a decrease in nutrient-dense food consumption, which may, in part, explain this population's increasing chronic disease rates. Because the available literature is limited, the present study aimed to document the ext... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Diet', 'Eating', 'Educational Status', 'Energy Intake', 'Family Characteristics', 'Feeding Behavior', 'Female', 'Fruit', 'Humans', 'Inuits', 'Life Style', 'Logistic Models', 'Male', 'Middle Aged', 'Northwest Territories', 'Social Class', 'Socioeconomic ... | 21,158,963 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['N01.824.196'], ['G07.203.650.240.340'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Ge... | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses. | BACKGROUND: Teriflunomide, a dihydro-orotate dehydrogenase inhibitor, has immunomodulatory effects, including the ability to suppress experimental allergic encephalomyelitis. In this randomized, double-blind, placebo-controlled Phase II study, the authors examined the safety and efficacy of oral teriflunomide in multip... | ['Adult', 'Double-Blind Method', 'Female', 'Headache', 'Humans', 'Immunologic Factors', 'Isoxazoles', 'Leflunomide', 'Male', 'Middle Aged', 'Multiple Sclerosis, Relapsing-Remitting', 'Nausea'] | 16,567,708 | [['M01.060.116'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477'], ['D03.383.129.385'], ['D03.383.129.385.475'], ['M01.060.116.630'], ['C10.114.375.500.600', 'C10.314.350.500.600', 'C20.11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Energy expenditure during walking in patients with scoliosis. The effect of the Milwaukee brace. | Oxygen uptake during treadmill walking was measured in 8 scoliotic patients with idiopathic curves ranging from 25 to 60 degrees. The patients were fitted with a Milwaukee brace and the test was repeated within 2 or 3 days to study the effect of the brace on energy expenditure, mechanical work, and ventilatory function... | ['Adolescent', 'Braces', 'Energy Metabolism', 'Female', 'Heart Rate', 'Humans', 'Locomotion', 'Male', 'Oxygen Consumption', 'Respiratory Function Tests', 'Scoliosis'] | 741,237 | [['M01.060.057'], ['E07.858.442.743.319'], ['G03.295'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568.500', 'G11.427.410.568'], ['G03.680'], ['E01.370.386.700'], ['C05.116.900.800.875']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene. | The murine gap junction protein connexin43 (Cx43) is expressed in blood vessels, with vastly different contribution by endothelial and smooth muscle cells. We have used the Cre recombinase under control of TIE2 transcriptional elements to inactivate a floxed Cx43 gene specifically in endothelial cells. Cre-mediated del... | ['Animals', 'Blood Pressure Determination', 'Connexin 43', 'DNA', 'Embryo, Mammalian', 'Endothelium, Vascular', 'Gene Expression', 'Gene Targeting', 'Genes, Reporter', 'Humans', 'Immunoenzyme Techniques', 'Integrases', 'Lac Operon', 'Mice', 'Mice, Transgenic', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide Synthase', '... | 11,135,457 | [['B01.050'], ['E01.370.370.140', 'E01.370.600.100'], ['D12.776.543.585.250.200'], ['D13.444.308'], ['A16.254'], ['A07.015.700.500', 'A10.272.491.355'], ['G05.297'], ['E05.393.335'], ['G05.360.340.024.340.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-SARS drug screening by molecular docking. | Starting from a collection of 1386 druggable compounds obtained from the 3D pharmacophore search, we performed a similarity search to narrow down the scope of docking studies. The template molecule is KZ7088 (Chou et al., 2003, Biochem Biophys Res Commun 308: 148-151). The MDL MACCS keys were used to fingerprint the mo... | ['Antiviral Agents', 'Binding Sites', 'Drug Design', 'Hydrogen Bonding', 'Ligands', 'Microbial Sensitivity Tests', 'Models, Molecular', 'Protein Conformation', 'SARS Virus', 'Structure-Activity Relationship'] | 16,715,412 | [['D27.505.954.122.388'], ['G02.111.570.120'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['G02.282'], ['D27.720.470.480'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E05.599.595'], ['G02.111.570.820.709'], ['B04.820.578.500.540.150.113.937'], ['G02.111.830', 'G07.690.773.9... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomic imprinting: summary of an NICHD conference. | Compelling evidence for genomic imprinting as a pathogenetic mechanism in humans mandates re-evaluation of every genetic or multifactorial disease for parent-of-origin effects. In an expanding list of malformation syndromes, cancers, growth abnormalities, and chromosomal disorders, phenotypes may be determined by sourc... | ['Animals', 'Chromosome Aberrations', 'Dosage Compensation, Genetic', 'Fragile X Syndrome', 'Humans', 'Intellectual Disability', 'National Institutes of Health (U.S.)', 'Neoplasms', 'United States'] | 8,103,287 | [['B01.050'], ['C23.550.210', 'G05.365.590.175'], ['G05.308.203.249'], ['C10.597.606.360.455.500', 'C16.131.260.830.300', 'C16.320.180.830.300', 'C16.320.322.500.500', 'C16.320.400.525.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['I01... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
TCTP regulates spindle microtubule dynamics by stabilizing polar microtubules during mouse oocyte meiosis. | Dynamic changes in spindle structure and function are essential for maintaining genomic integrity during the cell cycle. Spindle dynamics are highly dependent on several microtubule-associated proteins that coordinate the dynamic behavior of microtubules, including microtubule assembly, stability and organization. Here... | ['Animals', 'Biomarkers, Tumor', 'Female', 'Gene Knockdown Techniques', 'Kinetochores', 'Meiosis', 'Mice', 'Microtubule-Associated Proteins', 'Microtubules', 'Oocytes', 'Phosphorylation', 'Protein Kinases', 'Protein Processing, Post-Translational', 'Spindle Apparatus', 'Spindle Poles'] | 26,802,898 | [['B01.050'], ['D23.101.140'], ['E05.393.335.500'], ['A11.284.430.106.279.345.190.160.165.500', 'G05.360.160.165.500'], ['G04.144.220.220.687', 'G05.113.220.687'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.284.430.214.190.750.602'], ['A05.360.490.690.680', 'A11.497.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protein tyrosine kinase and protein phosphotyrosine phosphatase in normal and psoriatic skin. | Protein tyrosine kinase and protein phosphotyrosine phosphatase activities were measured in extracts of skin samples from patients with psoriasis. Both kinase and phosphatase activities were significantly greater in samples taken from an involved area, characterized by epidermal hyperproliferation, than from adjacent s... | ['DNA', 'Epidermal Growth Factor', 'Humans', 'Kinetics', 'Phosphoprotein Phosphatases', 'Platelet-Derived Growth Factor', 'Protein Kinases', 'Protein-Tyrosine Kinases', 'Psoriasis', 'Skin'] | 6,322,856 | [['D13.444.308'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.352.650.625'], ['D12.644.276.910', 'D12.776.124.625', 'D12.776.467.910', 'D23.529.910'], ['D08.811.913.696.620.682'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Diffuse Luminance Flicker Light Stimulation on Total Retinal Blood Flow Assessed With Dual-Beam Bidirectional Doppler OCT. | Purpose: We assess the increase in total retinal blood flow (TRBF) induced by flicker stimulation of the human retina in vivo and investigate the flicker induced hyperemia by means of a vascular flow model of the retinal circulation to study neurovascular coupling (NC).Methods: In six healthy subjects, TRBF was measure... | ['Adult', 'Blood Flow Velocity', 'Female', 'Flicker Fusion', 'Fourier Analysis', 'Humans', 'Laser-Doppler Flowmetry', 'Male', 'Models, Theoretical', 'Photic Stimulation', 'Regional Blood Flow', 'Retina', 'Retinal Vessels', 'Tomography, Optical Coherence', 'Vasodilation'] | 28,245,297 | [['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.380.245', 'F02.463.593.932.458', 'G14.370'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.475', 'E05.830.500'], ['E05.599'], ['E05.723.729'], ['G09.330.100.780'], ['A09.371.729'], ['A07.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Model-based quantification of cerebral hemodynamics as a physiomarker for Alzheimer's disease? | Previous studies have found that Alzheimer's disease (AD) impairs cerebral vascular function, even at early stages of the disease. This offers the prospect of a useful diagnostic method for AD, if cerebral vascular dysfunction can be quantified reliably within practical clinical constraints. We present a recently devel... | ['Alzheimer Disease', 'Blood Flow Velocity', 'Blood Pressure', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Male', 'Models, Cardiovascular'] | 23,771,298 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of a biosurfactant on oxygen transfer in a cyclone column reactor. | A laboratory-scale cyclone column reactor was tested to determine how its oxygen transfer characteristics were affected by surfactants in the liquid medium. The volumetric oxygen transfer coefficient was greatly decreased by small quantities of the synthetic surfactants dodecyltrimethylammonium bromide and sodium dodec... | ['Bacillus subtilis', 'Bacterial Proteins', 'Cell Division', 'Industrial Microbiology', 'Lipopeptides', 'Oxygen', 'Peptides, Cyclic', 'Quaternary Ammonium Compounds', 'Sodium Dodecyl Sulfate', 'Surface-Active Agents'] | 1,367,431 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['H01.158.273.540.460', 'J01.897.120.460'], ['D10.477', 'D12.644.365'], ['D01.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Arginase-2 protects myocardial ischemia-reperfusion injury via NF-êB/TNF-á pathway. | OBJECTIVE: Arginase-2 exerts an anti-inflammatory potential. However, whether nuclear factor-êB (NF-êB)/TNF-á (tumor necrosis factor-á) pathway is involved in the anti-inflammation effect of arginase-2 has not been fully elucidated. Our study aims to explore the regulatory role of arginase-2 on ischemia-reperfusion inj... | ['Animals', 'Anti-Inflammatory Agents', 'Apoptosis', 'Arginase', 'Cell Proliferation', 'Creatine Kinase, MB Form', 'Cytoprotection', 'Disease Models, Animal', 'Heart Rate', 'L-Lactate Dehydrogenase', 'Male', 'Myocardial Infarction', 'Myocardial Reperfusion Injury', 'Myocytes, Cardiac', 'NF-kappa B', 'Rats, Sprague-Dawl... | 30,338,823 | [['B01.050'], ['D27.505.954.158'], ['G04.146.954.035'], ['D08.811.277.913.292'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.913.696.640.150.625'], ['G07.690.773.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship between anxiety and stuttering: a multidimensional approach. | UNLABELLED: The relationship between anxiety and stuttering is equivocal from both clinical and empirical perspectives. This study examined the relationship within the framework of the multidimensional interaction model of anxiety that includes an approach to general anxiety in specific situations [J. Pers. Soc. Psycho... | ['Adolescent', 'Adult', 'Anxiety', 'Humans', 'Male', 'Reproducibility of Results', 'Speech Production Measurement', 'Stuttering', 'Surveys and Questionnaires'] | 15,178,129 | [['M01.060.057'], ['M01.060.116'], ['F01.470.132'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E01.370.760'], ['C10.597.606.150.500.800.750', 'C23.888.592.604.150.500.800.750'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pepino mosaic virus genotype shift in North America and development of a loop-mediated isothermal amplification for rapid genotype identification. | BACKGROUND: Pepino mosaic, once an emerging disease a decade ago, has become endemic on greenhouse tomatoes worldwide in recent years. Three distinct genotypes of Pepino mosaic virus (PepMV), including EU, US1 and CH2 have been recognized. Our earlier study conducted in 2006-2007 demonstrated a predominant EU genotype ... | ['Genetic Variation', 'Genotype', 'Lycopersicon esculentum', 'Molecular Sequence Data', 'North America', 'Nucleic Acid Amplification Techniques', 'Plant Diseases', 'Potexvirus', 'Sequence Analysis, DNA', 'Virology'] | 23,587,202 | [['G05.365'], ['G05.380'], ['B01.650.940.800.575.912.250.908.500.322'], ['L01.453.245.667'], ['Z01.107.567'], ['E05.393.620'], ['G15.610'], ['B04.715.260.575', 'B04.820.578.375.575'], ['E05.393.760.700'], ['H01.158.273.540.859']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
Phenotypic divergence despite high levels of gene flow in Gal?pagos lava lizards (Microlophus albemarlensis). | The extent of evolutionary divergence of phenotypes between habitats is predominantly the result of the balance of differential natural selection and gene flow. Lava lizards (Microlophus albemarlensis) on the small island of Plaza Sur in the Gal?pagos archipelago inhabit contrasting habitats: dense vegetation on the we... | ['Analysis of Variance', 'Animals', 'Body Weight', 'Body Weights and Measures', 'Ecuador', 'Environment', 'Gene Frequency', 'Genetic Variation', 'Genetics, Population', 'Geography', 'Lizards', 'Microsatellite Repeats', 'Phenotype', 'Psychomotor Performance'] | 15,723,677 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['Z01.107.757.362'], ['G16.500.275', 'N06.230'], ['G05.330'], ['G05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Nursing education in China: past, present and future. | BACKGROUND: The development of nursing education in China is closely tied with the country's wider context, including the social, political and economic environment.EVALUATION: The source of information includes published materials accessible to the public and the authors' knowledge as content experts of the nursing si... | ['China', 'Curriculum', 'Education, Nursing', 'Education, Nursing, Graduate', 'History, 19th Century', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Nursing Education Research'] | 22,229,899 | [['Z01.252.474.164'], ['I02.158'], ['I02.358.462'], ['I02.358.337.450', 'I02.358.462.565'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.390.413', 'H02.478.395.413', 'I02.358.462.612', 'N04.590.233.508.613.413']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
[Cancer pain and evaluation of the pain: preface and comments]. | Cancer pain is very unpleasant often difficult to treat. Therefore, we should recognize the mechanisms of cancer pain and know the physical pain, psychological pain, social pain and spiritual pain as total pain. Besides, we must understand how to evaluate the cancer pain using the methods of assessment of cancer pain, ... | ['Humans', 'Neoplasms', 'Pain'] | 21,950,030 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444']] | ['Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Use of temperature coefficients of Kovach indexes in the identification of barbiturates]. | The conditions of direct gas chromatographic assessment of barbiturates in reference solutions and cadaveric material extracts were analyzed with the aim of their unification. Along with the Kovach indexes, their temperature coefficients seem promising for the identification of barbiturates. Critical parameters of the ... | ['Barbiturates', 'Chromatography, Gas', 'Forensic Medicine', 'Humans', 'Temperature'] | 8,036,637 | [['D03.383.742.698.253'], ['E05.196.181.349'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
A successful Charter challenge to medicare? Policy options for Canadian provincial governments. | In September 2016, a case went to trial in British Columbia that seeks to test the constitutionality of provincial laws that (1) ban private health insurance for medically necessary hospital and physician services; (2) ban extra-billing (physicians cannot charge patients more than the public tariff); and (3) require ph... | ['Canada', 'Humans', 'Insurance, Health', 'National Health Programs', 'State Government'] | 29,576,023 | [['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['N03.349.550'], ['I01.409.775', 'N03.540.348.875']] | ['Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Introduction to the special section on seeking new clinical research methods. | This Special Section introduces a new section of the Journal of Consulting and Clinical Psychology that will be periodically offered in future issues under the title "Clinical Research Methods." This introduction describes (a) the section's goals, (b) a conceptual framework and potential areas of methodological develop... | ['Behavior Therapy', 'Clinical Protocols', 'Humans', 'Models, Statistical', 'Psychotherapy', 'Research Design'] | 2,002,146 | [['F04.754.137'], ['E02.183', 'N05.715.360.330.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['F04.754'], ['E05.581.500', 'H01.770.644.728']] | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Mycolactone gene expression is controlled by strong SigA-like promoters with utility in studies of Mycobacterium ulcerans and buruli ulcer. | Mycolactone A/B is a lipophilic macrocyclic polyketide that is the primary virulence factor produced by Mycobacterium ulcerans, a human pathogen and the causative agent of Buruli ulcer. In M. ulcerans strain Agy99 the mycolactone polyketide synthase (PKS) locus spans a 120 kb region of a 174 kb megaplasmid. Here we hav... | ['Animals', 'Bacterial Toxins', 'Buruli Ulcer', 'Culicidae', 'Female', 'Gene Expression Regulation, Bacterial', 'Humans', 'Insect Vectors', 'Macrolides', 'Mice', 'Mice, Inbred BALB C', 'Mycobacterium ulcerans', 'Polyketide Synthases', 'Promoter Regions, Genetic', 'Virulence'] | 19,936,295 | [['B01.050'], ['D23.946.123'], ['C01.150.252.410.040.552.475.247', 'C17.800.893.295'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['G05.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
"The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016. | BACKGROUND: Between 1957 and 1962 thalidomide was used as a nonaddictive, nonbarbiturate sedative that also was successful in relieving the symptoms of morning sickness in early pregnancy. Infamously, thousands of babies were subsequently born with severe birth defects. The drug is used again, today, to successfully tr... | ['Abnormalities, Drug-Induced', 'Adult', 'Aging', 'Child', 'Disabled Persons', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Immunosuppressive Agents', 'Interdisciplinary Studies', 'Leprostatic Agents', 'Middle Aged', 'Pharmacovigilance', 'Pregnancy', 'Quality of Life', 'Thalidomide', 'United Kingdom'] | 28,398,668 | [['C16.131.042'], ['M01.060.116'], ['G07.345.124'], ['M01.060.406'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['D27.505.696.477.656'], ['I02.158.405'], ['D27.505.954.122.085.777'], ['M01.060.116.630'], ['E05.337.800.600', 'N06.850.505.636'], ['G08... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Biodegradation of poly(butylene succinate) powder in a controlled compost at 58°C evaluated by naturally-occurring carbon 14 amounts in evolved CO(2) based on the ISO 14855-2 method. | The biodegradabilities of poly(butylene succinate) (PBS) powders in a controlled compost at 58 degrees C have been studied using a Microbial Oxidative Degradation Analyzer (MODA) based on the ISO 14855-2 method, entitled "Determination of the ultimate aerobic biodegradability of plastic materials under controlled compo... | ['Biodegradation, Environmental', 'Butylene Glycols', 'Carbon Dioxide', 'Carbon Radioisotopes', 'Graphite', 'Mass Spectrometry', 'Oxidation-Reduction', 'Polymers', 'Soil Microbiology', 'Temperature'] | 20,057,944 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['D02.033.455.125'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D01.268.150.300', 'D01.578.300'], ['E05.196.566'], ['G02.700', 'G03.295.531'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['H01.158.27... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Expression and subcellular localization of mechano-growth factor in osteoblasts under mechanical stretch. | Mechano-growth factor (MGF) is a stretch sensitive factor in myocytes, and it might also be produced by other mechanocytes under mechanical stimulation. In this study, both the mRNA and protein expression of MGF were detected in stretched osteoblasts. Quantitative analysis showed that a cyclic stretching stimulation ca... | ['Animals', 'Animals, Newborn', 'Blotting, Western', 'Cell Nucleus', 'Cells, Cultured', 'Fluorescent Antibody Technique', 'Gene Expression Regulation', 'Insulin-Like Growth Factor I', 'Osteoblasts', 'Rabbits', 'Rats', 'Rats, Wistar', 'Reverse Transcriptase Polymerase Chain Reaction', 'Stress, Mechanical', 'Time Factors... | 19,911,128 | [['B01.050'], ['B01.050.050.282'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bucindolol improves right ventricle function in rats with pulmonary arterial hypertension through the reversal of autonomic imbalance. | Pulmonary arterial hypertension (PAH) is characterised by an elevation in afterload imposed on the right ventricle (RV), leading to hypertrophy and failure. The autonomic nervous system (ANS) plays a key role in the progression to heart failure, and the use of beta-blockers attenuates this process. The aim of this stud... | ['Animals', 'Autonomic Nervous System', 'Blood Pressure', 'Electrocardiography', 'Heart Ventricles', 'Hypertension, Pulmonary', 'Male', 'Monocrotaline', 'Propanolamines', 'Rats', 'Rats, Wistar', 'Ventricular Pressure'] | 28,011,346 | [['B01.050'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.560'], ['C08.381.423', 'C14.907.489.556'], ['D03.132.716.500', 'D03.633.100.772.500'], ['D02.033.100.624', 'D02.033.755.624', 'D02.092.063.624'], ['B01.050.150.900.649.313.992.635.505.700'], ... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prasugrel Use in Real Life: A Report From the Outpatient Setting in France. | The objective of this study was to provide descriptive statistics on patterns of prasugrel usage in the outpatient setting in France. This retrospective study was conducted to describe treatment patterns for prasugrel in the outpatient setting in France using the Intercontinental Marketing Services (IMS) Disease Analyz... | ['Acute Coronary Syndrome', 'Aged', 'Costs and Cost Analysis', 'Female', 'France', 'Humans', 'Male', 'Middle Aged', 'Outpatients', 'Platelet Aggregation Inhibitors', 'Prasugrel Hydrochloride', 'Retrospective Studies'] | 27,299,993 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116.100'], ['N03.219.151'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.643.630'], ['D27.505.954.502.780'], ['D02.886.778.600', 'D03.383.606.800', 'D03.383.903.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750'... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Process development for ethical recruitment of patients into simultaneous clinical studies in a chiropractic research clinic. | OBJECTIVE: To develop a process at one institution that creates an ethical means to bring other research projects to the attention of an individual who was excluded from the project for which they originally expressed interest, and to discuss the ethical issues surrounding patient recruitment and enrollment.METHOD: Gen... | ['Chiropractic', 'Clinical Protocols', 'Data Collection', 'Humans', 'Informed Consent', 'Iowa', 'Organizational Case Studies', 'Patient Selection', 'Program Development'] | 17,509,438 | [['H02.110'], ['E02.183', 'N05.715.360.330.125'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['Z01.107.567.875.510.370'], ['N03.349.380.710', 'N05.715... | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
A survey of self-perceived educational needs of general dental practitioners in the Merseyside region. | AIM: The aim of this study was to evaluate the self-perceived educational needs of a randomly selected group of general dental practitioners (GDPs) in the Merseyside region (UK).MATERIALS AND METHODS: Eighty-seven GDPs were randomly selected from 850 in the region and asked to complete a self-evaluation questionnaire r... | ['Anesthesiology', 'Attitude of Health Personnel', 'Conscious Sedation', 'Dental Implantation', 'Dentistry, Operative', 'Education, Dental, Continuing', 'Endodontics', 'England', 'Female', 'General Practice, Dental', 'Humans', 'Male', 'Needs Assessment', 'Oral Medicine', 'Orthodontics', 'Pediatric Dentistry', 'Periodon... | 16,004,713 | [['H02.403.066'], ['F01.100.050', 'N05.300.100'], ['E03.250'], ['E04.545.550.280', 'E04.650.230', 'E06.645.550.280', 'E06.780.314'], ['E06.323', 'H02.163.180'], ['I02.358.212.249', 'I02.358.274.316'], ['E06.397', 'H02.163.876.213'], ['Z01.542.363.300'], ['H02.163.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Physician respect for patients with obesity. | INTRODUCTION: Obesity stigma is common in our society, and a general stigma towards obesity has also been documented in physicians. We hypothesized that physician respect for patients would be lower in patients with higher body mass index (BMI).METHODS: We analyzed data from the baseline visit of 40 physicians and 238 ... | ['Aged', 'Attitude of Health Personnel', 'Body Mass Index', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Patient Satisfaction', 'Physician-Patient Relations', 'Prejudice'] | 19,763,700 | [['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The incidence and prevalence of dermatitis herpetiformis in Utah. | BACKGROUND AND DESIGN: The incidence and prevalence of dermatitis herpetiformis has never been formally evaluated in any area of the United States. Several northern European studies have shown prevalence rates ranging from 1.2 per 100,000 to 39.2 per 100,000. The present study was performed to evaluate the incidence an... | ['Adult', 'Aged', 'Aged, 80 and over', 'Dermatitis Herpetiformis', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prevalence', 'Prospective Studies', 'Seasons', 'Utah'] | 1,456,754 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C17.800.174.360', 'C17.800.865.360', 'C20.111.318'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['E05.318.308.985... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mentors' perceptions and experiences of supporting student nurses in practice. | This paper reports on a funded project that explored the perceptions and experiences of mentors regarding student nurse support in practice. The study employed a mixed-method approach, using questionnaires and focus groups with mentors from one acute Trust and one community Trust. The findings highlighted the multiface... | ['Adult', 'Attitude of Health Personnel', 'England', 'Focus Groups', 'Humans', 'Mentors', 'Nursing Education Research', 'Social Support', 'Students, Nursing', 'Surveys and Questionnaires'] | 25,157,940 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['Z01.542.363.300'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.395'], ['H01.770.644.145.390.413', 'H02.478.395.413', 'I02.358.462.612', 'N04.590.233.508.613.413'], ['I01.880.853.500.600'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Identification and genotyping of hepatitis C virus in injectable and oral drug users in New Zealand. | BACKGROUND: Hepatitis C virus infections are known to be common in injectable drug users (IDU) both in New Zealand and overseas. Little is known of the hepatitis C genotype frequency in this population.AIMS: To confirm the high incidence of hepatitis C virus infections in IDU and compare this with the frequency in oral... | ['Adult', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis Antibodies', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Incidence', 'Male', 'New Zealand', 'Polymerase Chain Reaction', 'RNA, Viral', 'Substance Abuse, Intravenous', 'Substance-Related Disorders'] | 7,516,149 | [['M01.060.116'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.114.254.450', 'D12.776.377.715.548.114.254.450'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['D12.776.124.486.485.114.254.450.510', 'D12.776.124.790... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The outcome of haemopoietic stem cell transplantation in the treatment of lymphoplasmacytic lymphoma in the UK: a British Society Bone Marrow Transplantation study. | Lymphoplasmacytic lymphoma (LL) is incurable by standard therapy (median survival: 60 months). UK transplant registry data 1984-2003 identified 18 cases of histologically verified LL (median age: 50 years, range: 38-58 years). Nine patients received high dose chemotherapy [plus total body irradiation (TBI) in 1/9] and ... | ['Adult', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Karnofsky Performance Status', 'Male', 'Middle Aged', 'Registries', 'Survival Analysis', 'Transplantation Conditioning', 'Treatment Outcome', 'United Kingdom', 'Waldenstrom Macroglobulinemia'] | 18,616,880 | [['M01.060.116'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.475.456.500.500', 'N05.715.360.300.800.438.375.364.500.500', 'N06.850.520.308.980.438.475.364.500.500'], ['M01.060.116.630'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Very early predictors of conduct problems and crime: results from a national cohort study. | BACKGROUND: Longitudinal research has produced a wealth of knowledge about individual, family, and social predictors of crime. However, nearly all studies have started after children are age 5, and little is known about earlier risk factors.METHODS: The 1970 British Cohort Study is a prospective population survey of ... | ['Adult', 'Age Factors', 'Antisocial Personality Disorder', 'Behavior, Addictive', 'Child', 'Child, Preschool', 'Conduct Disorder', 'Crime', 'England', 'Female', 'Health Records, Personal', 'Humans', 'Infant, Newborn', 'Longitudinal Studies', 'Male', 'Maternal Behavior', 'Parents', 'Personality Assessment', 'Personalit... | 20,633,069 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F03.675.050'], ['F01.145.527.100.120'], ['M01.060.406'], ['M01.060.406.448'], ['F03.625.094.300'], ['I01.198.240', 'I01.880.735.191'], ['Z01.542.363.300'], ['E05.318.308.940.968.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Internet-based treatment for insomnia: a controlled evaluation. | This study investigated the effects of an Internet-based intervention for insomnia. Participants who met criteria for insomnia (N = 109) were randomly assigned to either a cognitive-behavioral self-help treatment or a waiting list control condition. The 5-week intervention mainly consisted of sleep restriction, stimulu... | ['Adolescent', 'Cognitive Behavioral Therapy', 'Female', 'Humans', 'Internet', 'Male', 'Self-Help Groups', 'Sleep Initiation and Maintenance Disorders', 'Surveys and Questionnaires'] | 14,756,620 | [['M01.060.057'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['N03.540.782'], ['C10.886.425.800.800', 'F03.870.400.800.800'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Excessive leakage radiation measured on two mobile X-ray units due to the methodology used by the manufacturer to calculate and specify the required tube shielding. | During the quality control (QC) procedure of a new mobile X-ray unit, it was revealed that the leakage radiation was well in excess of the current limit of 1 mSv h(-1). As a result, this unit was returned to the vendor company and it was replaced by a new unit of the same brand and model. Leakage measurements revealed ... | ['Calibration', 'Equipment Design', 'Humans', 'Mobile Health Units', 'Quality Control', 'Radiation Dosage', 'Radiation Protection', 'Radiography', 'Radiometry'] | 16,489,198 | [['E05.978.155'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.421.702', 'N02.421.726.233.628'], ['J01.897.608'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['N06.850.810.425'], ['E01.370.350.700'], ['E05.799']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Modification of the association between alcohol drinking and non-HDL cholesterol by gender. | BACKGROUND: Serum non-HDL cholesterol is a strong predictor of cardiovascular diseases. We studied the relationship between habitual alcohol drinking and non-HDL cholesterol.METHODS: Healthy male subjects (n = 27,005) and female subjects (n = 16,805) were divided into 5 groups by average daily ethanol intake. Serum non... | ['Adult', 'Alcohol Drinking', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Ethanol', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sex Factors'] | 19,336,233 | [['M01.060.116'], ['F01.145.317.269'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['D02.033.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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