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Arlt line is a feature of trachoma. Ref: Kanski 8th/e Chap.5, p.138
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Hematemesis is suggestive of massive upper GI bleed, the impoant causes of which in descending order are Peptic ulcer Duodenal ulcer (MC cause) Gastric ulcer Esophageal varies Gastritis Mallory Weiss tear Neoplasm of esophagus, stomach and duodenum Duodenal ulcer: Peptic ulcer is the most common cause of upper GI bleed...
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TEMPORARY SOCIAL GROUPS (1) The Crowd : When a group of people come together temporarily, for a sho period, motivated by a common interest or curiosity (e.g., to witness a football match), it is known as a crowd. The crowd lacks internal organization and leadership. When the interest is over, the crowd disperses. (2) T...
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Ans. is 'c' ie Oromandibular limb defects " Chorionic villous sampling is usually performed at 10-13 weeks and is associated with several complications but studies suggests that limb reduction and oromandibular limb hypogenesis is more common if CVS is done before 9 weeks so CVS is done after 9 wks because it is more s...
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Ans. D: Cost effective analysis Cost-effectiveness analysis (CEA) is a form of economic analysis that compares the relative costs and outcomes (effects) of two or more courses of action. Cost-effectiveness analysis is distinct from cost-benefit analysis, which assigns a monetary value to the measure of effect. Cost-eff...
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Ans: C (Type III) Ref: Ananthnarayan R, Paniker CKJ. Textbook of Microbiology. 8th Edition. Hyderabad: Universities Press: 2009. Pg. 161-168Explanation:HYPERSENSITIVITYGell and Coomb classificationType I - IgE mediated- anaphylaxis and atopyType II- cytotoxic or cytolyticType III- immune complex mediatedType IV- T cell...
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Spider angiomas form due to failure of the sphincteric muscle surrounding a cutaneous aeriole. The central red dot is the dilated aeriole and the red "spider legs" are small capillaries carrying away the freely flowing blood. If momentary pressure is applied, it is possible to see the emptied capillaries refilling from...
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• Esophageal contractions are repetitive, simultaneous, and of high amplitude. • Basic pathology is related to a motor abnormality of the esophageal body that is most notable in the lower two thirds of the esophagus. • More common in women and is often found in patients with multiple complaints. Clinical Features] • Cl...
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Ans. is 'a' i.e., Chest infection Most common complication after splenectomy is left lower lobe atelactasis. Atelactasis predisposes to chest infections.
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Down syndrome or trisomy 21 is the most common chromosomal anomaly.
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Ans. B. 15 monthsA 15 month old child has a vocabulary of 10-15 meaningful words. However at this time since less than 20% of the speech is understood, the main mode of communication remains non-verbal.
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Purkinje cells of Cerebellum shows complete disintegration.
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Ref: Ananthnarayan R. Paniker CKJ. Textbook of Microbiology. 8th Edition. Hyderabad: Universities Press: 2009. Pg. 601-15.Explanation:Dimorphic fungi can occur as filaments or as yeasts, depending on the conditions of growth.In host tissues or cultures at 37degC they occur as yeasts, while in the soil and in cultures a...
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Best way to know the position and integrity of ICD is to do a plain radiograph.
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Ans. A i.e. 1000 gm
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Black is used for noninfectious waste Red-plastic bag -sharps Blue-non chlorinated plastic bag Ref: Textbook of Microbiology Baveja 5th ed Pg 641
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Category 1. Pulmonary aerial hypeension (PAH) Key feature: elevation in pulmonary aerial pressure (PAP) with normal pulmonary capillary wedge pressure (pcwp) Includes: Idiopathic (IPAH) * Sporadic * Familial * Exposure to drugs or toxins * Persistent pulmonary hypeension of the newborn * Pulmonary capillary hemangiomat...
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Glycogen storage disease (GSD; type V)(McArdle disease): Deficiency of myophosphorylase (muscle glycogen phosphorylase) enzyme that catalyzes the removal of glucose residues from glycogen to form glucose-1-phosphate that ultimately enters glycolysis to provide muscle energy. Also Know: In McArdle disease only the skele...
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A i.e. Atropine Treatment of hypeensive uveitis is treatment of acute iridocyclitis (Mydriatic-cycloplegic-steroidantibiotics), topical (3 blocker (e.g. timolol), carbonic anhydrase inhibitor (acetazolamide) dipivefrine. Secondary glaucoma Q (due to posterior synechiae formation) is the m.c. complication of recurrent a...
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Ans. (c) Separation of sensory retina from pigment epitheliumRef: Kanski 7/e, p. 689, 701* Retinal detachment: Separation of NSR from RPE, leading to accumulation of fluid in sub retinal spaceRetinoschisis (splitting of retina)Typical/degenerative split in OPLReticular/congential split at NFL
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Ans. b-2 transferrin
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A. i.e. Posterior wall of stomach - Lesser sac/ Omental bursa is bounded anteriorly by stomach, caudate lobe of liver, lesser omentum & greater omentum (ant. 2 layers); and posteriorly by structures forming stomach bed (i.e. diaphragm, pancreas, spleen etc) & greater omentum (posterior 2 layers) Lesser sac or omental b...
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Ans. is `b: i.e., FPL
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C. i.e. Amnestic syndromes lose semantic memory
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Anteriors – 1mm / month Premolars – 4.5mm / 3 month Molar – 1mm / 3month
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Kawasaki disease is a vasculitis that mostly involves the coronary vessels. It presents as an acute systemic disorder, usually affecting children under 5 years. It occurs mainly in Japan and other Asian countries, such as China and Korea, but other ethnic groups may also be affected. Presentation is with fever, general...
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Ans. is 'a' i.e., P. aeruginosa Although otitis externa is also known as swimmer's ear, malignant otitis externa isn't due to water remaining in the ear canal. Bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus often cause malignant otitis externa. The most frequent pathogen is Pseudomonas aeruginosa.
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Ans. is 'a' i.e., Citric acid cycleMetabolic pathways fall into three categories :?Anabolic pathways:- Involved in synthesis of larger and more complex compounds from smaller precursors, e.g. synthesis of protein from amino acids, triglyceride synthesis, cholesterol synthesis, etc.Catabolic pathway:- Involved in the br...
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Chromothrypsis Phenomenon by which up to thousands of clustered chromosomal rearrangements occur in a single event in localized and confined genomic regions Involved in cancer (1% -2%)and congenital diseases. Osteosarcomas and gliomas as well. Chromosome breaks occur within pa or across the entirety of a single chromos...
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Paraneoplastic syndromes on HCC Hypercholesterolemia Hypoglycemia Erythrocytosis Hypercalcemia Hypercholesterolemia > Hypoglycemia > Erythrocytosis > Hypercalcemia Ref: Sabiston 20th edition Pgno : 1459
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Ans. is'b'i.e., AmiodaroneImPoant drug used in CPR are epinephrine, amiodarone, lidocaine, MgSOr, sodium bicarbonate and calcium gluconateThe routine use ofAtropine for PEA (pulseless Electrical Activity & asystole has no therapeutic benefit.Hence, Atropine has been removed from the cardiac arrest algorithm
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Minocycline = blue-black pigmentation (Slate like)
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Rituximab, Ofatumumab, Ocrelizumab & Obinutuzumab are monoclonal antibodies against Cd-20. Brentuximab acts against CD30.
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Ans. is 'b' i.e., Diamond-Blackfan syndrome
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Ans. B. Pathological doubtOC symptoms in adultsObsessions (N = 200)Contamination45Pathological doubt42Somatic36Need for symmetry31Aggressive28Sexual26Other13Multiple obsessions60Compulsions (N = 200)Checking63Washing50Counting36Need to ask or confess31Symmetry and precision28Hoarding18Multiple comparisons48
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Bitewing or interproximal radiographs include the crowns of the maxillary and mandibular teeth and the alveolar crest on the same film. The beam is angulated +7 to +10 degree vertically to preclude overlap of the cusps on the occlusal surface. Vertical angulation:  The aiming cylinder is positioned about +10 degrees to...
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Ans. is 'a' i.e., Subarachnoid hemorrhage Most common cause of subarachnoid hemorrhage Trauma Most common cause of spontaneoussubarachnoid hemorrhage Rupture of Berry aneurysm (or Saccular aneurysm) Also know Mycotic aneurysm ? Mycotic aneurysm is caused by a septic embolus that weakens the wall of the vessel in which ...
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There are following phases of gastric acid secretion: - 1. The cephalic phase:- Just as salivary secretion may start before food enters the mouth, gastric secretion is also indicated before food enters the stomach. Sight, smell or even thought of food stimulate gastric acid secretion. It is by the parasympathetic syst...
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Tubular or bronchial breath sounds is seen in lobar pneumonia or consolidation. Normally the breath sounds heard over the chest is vesicular. Reference : Davidson, 23rd Edition, page no :547.
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Trapezoid in cross sectionProstatic urethra is semilunar (transversely arched) in cross-sectionIn transverse section- Preprostatic pa --> Stellate (star shaped)- Prostatic pa -->Transversely arched (semilunar)- Membranous pa --> Stellate- Bulbar & penile -->Transverse- External orifice -->Sagittal
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ANSWER: (C) AdenocarcinomaREF: Novaks gynaecology 14th ed.pg no 1350Uterine sarcomas are, in general, the most malignant group of uterine tumorsAbout 90% of women with endometrial carcinoma have vaginal bleeding or discharge as their only presenting symptom.The risk for endometrial cancer is 4 to 8 times greater in pos...
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Prostate contributes 20% of the total volume of the semen. Secretion from the prostate contains the following: Spermine Citric acid Cholesterol, phospholipids Fibrinolysin, fibrinogenase Zinc Acid phosphatase From seminal vesicles: Fructose Phosphorylcholine Ergothioneine Ascorbic acid Flavins Prostaglandins Ref: Barre...
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Ethambutol may cause ‘optic neuritis’ (ocular toxicity): 463 National Health Programmes, Policies and Legislations in IndiaReview of Preventive and Social Medicine It may lead to ‘red-green color blindness’ Patients may thus develop ‘blue vision’ Thus it is contraindicated in children < 6 years age, as they may not be ...
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When the bladder is not empty, it rises above the level of the pubic symphysis. Other options given, do not reach the level of the pubic symphysis.
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Cubitus varus: decreased carrying angle Opposite condition of Cubitus varus is Cubitus valgus. Cubitus valgus: increased carrying angle. Other high yield points to be remembered: mannus is term used for denoting wrist joint mannus varus -ulnar detion of hand at wrist joint mannus valgus-radial detion of the hand at wri...
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Markers for low ovarian reserve AMH: Best marker for the ovarian reserve is the AMH. Released from small antral and pre- antral follicles <0.5 ng = Poor reserve 1ng = Borderline reserve >= 3.3 ng = high reserve , risk factor for OHSS in stimulated cycles high day 2 FSH (most commonly performed test) low inhibin B low a...
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Left-sided hea failure leads to pulmonary congestion and edema. There is extravasation of red cells and plasma proteins in the alveoli which are phagocytosed and digested by macrophages The accumulated iron from ingested red cells is stored as hemosiderin. These hemosiderin-laden macrophages are also known as hea failu...
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Case fatality rate = Total number of deaths due to a paicular disease/Total number of cases of the same disease It is a measure of the killing power of a disease and is closely related to the virulence. Ref: Park, Edition 21, Page - 54.
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D i.e. Lactase
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Ans. is 'c' i.e., Axons o Nodes of Ranvier are periodic gaps in the myelin sheath on the axon.o Neuron is the functional unit (basic unit of nervous tissue).o It is specialized for the function of reception, integration and transmission of information in the body,o The basic structure of neuron is best studied in a spi...
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Sucralfate polymerizes at pH < 4 by cross linking of molecules, assumes a sticky gel like consistency, and then preferentially and strongly adheres to ulcer base. Ranitidine would increase the gastric pH (lower acidity) and prevent action of sucralfate by preventing its polymenzation which occurs at pH values < 4. Ref:...
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A child with severe dehydration will have at least two of the following four signs: sensorium is abnormally sleepy or lethargic, sunken eyes, drinking poorly or not at all, and a very slow skin pinchA child with some signs of dehydration will have two of the following: restlessness or irritability, sunken eyes, drinkin...
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A i.e Familial fatal insomnia
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Phosphofructokinase catalyses the first committed step of glycolysis. It is the rate limiting enzyme of glycolysis. The reaction is irreversible.
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All mentioned drugs are used for medical management of endometriosis Drugs used for medical management of endometriosis NSAIDS Ibuprofen, naproxen, mefenamic acid Combined pills Progestins Medroxyprogesterone, NET-EN, DMPA, LND-IUD, dienogest GnRH agonists Leuprolide, goserelin, buserelin, nafarelin GnRH antagonists Ce...
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Ans: (b) PTENRef: WHO, FGT, Page 29-34Going with PTEN because it's the most common one mutated (Ref: WHO - >50%). P53 mutation is seen only in type 2 carcinomas, incidence of which is less. PTEN is seen in both type 1 and type 2 carcinomas.FeaturesType 1Type 2Prototypic formEndometrioid carcinomaUterine (papillary) ser...
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Decreased nutrients lead to atrophy. Chronic irritation leads to metaplasia.
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Ergotamine:- Mech of action:- It acts as a paial agonist and antagonist at a adrenergic and all subtypes of 5-HT1 and 5-HT2 receptors. It produces sustained vasoconstriction(leading to Acrocyanosis), visceral smooth muscle contraction, vasomotor centre depression and antagonizes the action of NA and 5-HT on smooth musc...
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Ans. is 'a' i.e., Inhibition of protein synthesis
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Muscles responsible for abduction of the shoulder joint -        Supraspinatus- first 15 degrees of abduction -        Deltoid (Acromial fibers)- it is responsible for abduction from 15 to 90 degrees. -        Trapezius and serratus anterior- They are responsible for upward rotation of the glenoid cavity.
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Ans. B. Troponina. Troponin, or the troponin complex, is a complex of three regulatory proteins (troponin C, troponin I and troponin T) that is integral to muscle contraction in skeletal muscle and cardiac muscle but not smooth muscle.b. Discussions of troponin often pertain to its functional characteristics and/or to ...
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Alveolar type II cells first appear in the 17 to 26 weeks of gestation. They are the surfactant producing cells. However, the process of surfactant production must mature to become efficient at reducing surface tension. Mature, functional surfactant is produced by 34-35 weeks. Since the question is - "surfactant produc...
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Subcapsular sinuses are seen in lymph node INDERBIR SINGH'S TEXTBOOK OF HUMAN HISTOLOGY SEVENTH EDITION PAGE NO133
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Ans. is `b' i.e., Blue Colour Defective Absent GreenRedBlue DeuteranomalousProtanomalousTritsnomalous DeuteranoPtaProtanopiaTritanopia
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Though the first option is true it is not the answer to the question. The spinal cord extends to the lower border of L3 in infants that is why we opt for a lower inter-veebral space in infants while doing a lumbar puncture. The dura, subdural space and subarachnoid space extends up to S2. The pia mater extends to the t...
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Ans. is 'd' i.e., Lymphnode of lund
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Single layer of varnish covers 55% of surface area.
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Phrenicocolic ligament and left colic flexure prevent downward displacement of enlarged spleen.
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Because of its protected retroperitoneal location, pancreatic injury occurs with deep penetrating wounds or with significant blunt trauma to upper abdomen. Blunt trauma accounts for less than 20-30% of all pancreatic injuries. The most common site of injury is at the neck of the pancreas where the pancreatic tissue is ...
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Intrauterine pressure is raised to 40-50 mmHg in the first stage 100-200 mmHg in the second stage 100-200 mmHg maintained in the third stage The diminished pain is due to lack of stretching effects D.C.DUTTA'S TEXTBOOK OF GYNECOLOGY,Pg no:117,7th edition
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Apolipoprotien B (major LDL protien) is better predictors of CHD. Ref-Park&;s textbook of Preventive and Social Medicine 24th edition.
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ANSWER: (B) Right sided extra fibresREF: Harrison s 18th ed ch: 233WPW is caused by the presence of an abnormal accessory electrical conduction pathway between the atria and the ventricles. Electrical signals travelling down this abnormal pathway (known as the bundle of Kent) may stimulate the ventricles to contract pr...
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Ans. a. Refraction with near add (Ref: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 0 8px; text-indent: 0">A 59-year-old male presents with dimness of near vision. On examination, the media was clear in both the eyes. For diminuation of vision this age. one should think ...
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Chest radiograph signs in PE are , Pallas sign – enlarged right descending pulmonary artery Hamptons hump- wedge shaped density above diaphragm Westermark sign- focal oligemia.
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Factor VII is a 56kd single chain, vitamin K dependent zymogen component of the extrinsic pathway of blood coagulation. So, its deficiency is associated with prolongation of PT not APTT. APTT is prolonged in case of deficiency of coagulation factors involved in intrinsic pathway. Ref: Autoantibodies By James B. Pete, P...
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Answer is A (Temporal Aery Biopsy): Temporal aery biopsy is the gold standard test for diagnosing giant cell Aeritis - Current Rheumatology The diagnosis of giant cell Aeritis is confirmed by Temporal Aery Biopsy-Harrisons Diagnosis of Giant cell Aeritis (GCA) 50 years" align="left" height="28" width="300">Diagnosis of...
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Ans. is 'a' i.e., Smaller airways Younger infants are more vulnerable because : - i) Smaller airways ii) More compliant chest wall iii) Poor hypoxic drive
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A continuous variable is a variable that has an infinite number of possible values. (ex: weight in Kgs - 48.6, 47.23.etc ) A discrete variable is a variable that can only take on a ceain number of values. (Ex: Number of doctors in a clinic - 5, 11..etc) Ref : Park 23rd edition Pgno : 73
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The mainstay treatment for borderline personality disorders is psychotherapy which includes behavior therapy-dialectical behavior therapy (DBT) -specific for borderline personality disorder. It is used especially for those with parasuicidal behavior, such as frequent cutting. Patients are seen weekly, with the goal of ...
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Endometrioid carcinomas closely resemble normal endometrium and may be exophytic or infiltrative . They include a range of histologic types, including those showing mucinous, tubal (ciliated), and squamous (occasionally adenosquamous) differentiation. ref : Robbins Basic Pathology, 9E,page-692
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Ans. a (Heart). (Ref. Ganong, Physiology, 21st ed., 557)Circulation through organs:Liver:Largest share of systemic cardiac output.Kidney:Highest blood flow per gram of tissue.Heart:Large arteriovenous 02 difference. HEARTWorkO2 usage(ml/100 g/min)Pulse rate(/min)CO (L/min)Stroke vol (ml)A-VO2 diff (ml/dl) Rest267646.41...
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Ans. (b) Separation of keratinocytesRef: Harrison 19th ed. / 370* Keratinocytes are connected to one another by intracellular desmosomal bridges.* If there is loss of these desmosomal bridges, it will lead to separation of keratinocytes and the condition is known as acantholysis.* If separation continues, there will be...
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(B) Acute hepatitis B with... COMMONLY ENCOUNTERED SEROLOGIC PATTERNS OF HEPATITIS B INFECTIONHBsAgAnti-HBsAnti-HBcHBeAgAnti-H BeInterpretation+-IgM+HIAcute hepatitis B, high infectivity+-IgG+-Chronic hepatitis B, high infectivity+-IgG-+1. Late acute or chronic hepatitis B, low infectivity2. HBeAg-negative ("precoremut...
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Acoustic neuroma and endolymphatic hydrops (Meniere's disease) can lead to SNHL and tinnitus (Dhingra 5/e p. 38). Meningioma can cause deafness, and tinnitus as a pa of Neurofibromatosis type 2 syndrome (Harrison 17th/ed p 2603) and its peak incidence occurs in middle age.
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The concept of applanation tonometry was introduced by Goldmann is 1954. It is based on Imbe- Fick law which states that the pressure inside a sphere (P) is equal to the force (W) required flattening its surface divided by the area of flattening (A); i.e., P = W/A. Reference: AK khurana 7th edition
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Investigations in Sarcoidosis Lymphopenia is characteristic and liver function tests may be mildly deranged. Hypercalcaemia may be present (reflecting increased formation of calcitriol - 1,25-dihydroxyvitamin D - by alveolar macrophages), paicularly if the patient has been exposed to strong sunlight. Hypercalciuria may...
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(A) Vulva[?]Paget's Disease of the Vulva:Also known as extra mammary Paget's Disease.Represents close to 1% of all vulvar cancers.Occurs in the late reproductive & post menopausal age group.Presents as pruritic & burning, red, crusted patches interspersed with white & ulcerated areas.Can be very extensive & multifocal....
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The severity, radiology and management of NEC are best exemplified by the Modified Ben stating Criteria'. MODIFIED BELL'S STAGING CRITERIA FOR NECROTIZING ENTEROCOLITIS
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Refer Robbins page no 843
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Glucose levels >70 mg/dL stimulate insulin synthesis, primarily by enhancing protein translation and processing.Glucose stimulation of insulin secretion begins with its transpo into the beta cell by a facilitative glucose transpoer. Glucose phosphorylation by glucokinase is the rate-limiting step that controls glucose-...
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Ans. is 'b' i.e., Attachment
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Ans. is 'b' i.e., The internal abdominal ring lies 1.25 cm. above the midpoint of poupa's ligament
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Ans. a (Asbestosis) (Ref. Grainger's Diagnostic Radiology, 4th ed., 513; TABLE 24-3)X-RAY FEATURES OF ASBESTOS EXPOSUREPleuralPulmonaryExtrathoracic# Plaques# Fibrosis (asbestosis)# Peritoneal mesothelioma# Diffuse thickening# Bronchial carcinoma# Other extrathorasic malignancies# Effusions# Round atelectasis (pseudotu...
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- Hydroxyurea increases HbF levels - used for treatment of sickle cell anemia. Management of Sickle cell anemia: Avoid infections & prompt correction of any inflammation Pneumococcal & HIB vaccination early in life Acute painful crisis - vigorous hydration & analgesia Bone marrow transplantation, gene therapy Hydroxyur...
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Trastuzumab Each of the drugs listed has been used in drug regimens for breast cancer, but only trastuzumab has specificity in its actions. The drug is a monoclonal antibody to a surface protein in breast cancer cells that over express the HER2 protein. Consequently, trastuzumab has value in a specific subset of breast...
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Ans. c (Mandibular nerve). (Ref. BD Chaurasia, Anatomy -3rd vol., 3rd ed., 73)Cavernous sinus.AnatomyPathology# Collection of venous sinuses on either side of pituitary.# Blood from eye and superficial cortex drain in cavernous sinus and then internal jugular vein.# CN III, IV, VI, V2, and V and postganglionic sympathe...
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Oligospermia is defined as a sperm count below 20 million/mL. Ref: Textbook of Gynecology By D C Dutta, 4th Edition, Pages 217, 218, 225 ; Current Obs and Gynae Diagnosis and Treatment 9th Edition, Page 982
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Ans. A: Sodium Nitroprusside Antihypeensive therapy in acute aoic dissection aims specifically to lessen pulsatile load or aoic stress, in order to retard the propagation of the dissection and prevent aoic rupture. The goals of treatment are to prevent myocardial ischemia, decrease left ventricular afterload, decrease ...
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Median nerve lies deep to the flexor retinaculum and is not damaged by cuts which are superficial. Structures crossing superficial to flexor retinaculum are:From medial to lateral:Superficial branch of ulnar nerve and ulnar aeryTendon of palmaris longusPalmar cutaneous branch of median nerveOrigin of the thenar muscles...
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Ans. is 'a' i.e., Aspergillus flavus o Aflatoxins are produced primarily by filamentous fungi Aspergillus fiavus and Aspergillus parasiticus.
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