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<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although chemical substances are a very important factor in the realization of current industrialization , because they were used indiscriminately w...
### Summary: : objectivesdespite the great contribution made by chemical substances to the development of modern civilization , their indiscriminate use has caused various kinds of damage to the global environment and human beings . accordingly , the major developed countries and international society have tried to...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : this randomized controlled study was conducted in a tertiary care teaching institute of rajasthan after taking approval from the institutional ethic...
### Summary: : objectives : to compare the efficacy and safety of febuxostat and allopurinol in pyrazinamide ( pza)-induced hyperuricemia in patients taking antitubercular therapy ( att).methods : this randomized controlled study was conducted at a tertiary care teaching institute of rajasthan in all the sputum - pos...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the adverse effects of asthma in pregnancy are related to asthma severity and the intensity of treatment [ 13 ] . acute asthma exacerbations have ...
### Summary: : there exists a paucity of data for socially disadvantaged populations describing patterns and predictors of asthma control status and exacerbations during pregnancy , and their relationship to adverse perinatal outcomes.asthmatic women ( n=189 ) were followed prospectively during pregnancy , with visit...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : bipolar disorder ( bd ) associated seasonal pattern ( mania during spring and summer together with depression during fall and winter ) referred to a...
### Summary: : background and aim : polymorphisms in aryl hydrocarbon receptor nuclear translocator - like ( arntl ) gene , the key component of circadian clock manifests circadian rhythm abnormalities . as seasonal affective disorder ( sad ) is associated with disrupted circadian rhythms , the main objective of this...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : it is the combination of feelings and perceptions which can affect and be affected by the culture of a society . moreover , individuals appearance...
### Summary: : background : rhinoplasty is the most common cosmetic surgery which has been dramatically increasing in iran . currently , iran is ranked the first in the world in rhinoplasty . in the present study , we aimed to assess the character and temperament traits of the applicants referred to rhinoplasty s...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the chinese atrial fibrillation registry ( cafr ) prospectively enrolled consecutive af patients from multiple centers , confirmed by objective test...
### Summary: : backgroundimpacts of a single radiofrequency ablation ( rfa ) on quality of life ( qol ) were not well investigated in atrial fibrillation ( af ) patients with low stroke risk.methods and resultsnine hundred af patients with low chads2 score ( ie , chads2 1 ) who completed both a baseline and 6-month a...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : takeuchi et al.1 explained that the transverse ligament becomes degenerated and hypertrophic because of chronic mechanical stress by atlantoaxial su...
### Summary: : retro - odontoid cysts associated with chronic atlantoaxial subluxation are extremely rare . this article describes a case of retro - odontoid cystic mass associated with chronic atlantoaxial subluxation and its management with posterior c1 and partial c2 laminectomy and c1-c2 pedicle screw fixation ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the residual or resistant clubfoot represents one of the most difficult treatment challenges for the pediatric orthopaedist . often residual defor...
### Summary: : dorsal rotatory subluxation of the navicular , a common sequela of resistant surgically treated clubfeet , presents a challenging treatment problem . this subluxation typically progresses after posteromedial release . patients develop a cavovarus foot deformity and complain of pain , gait problems ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : herpes zoster ( hz ) is an infectious disease caused by reactivation of latent varicella zoster infection . this common viral disease afflicts bet...
### Summary: : backgroundpain is a main symptom of herpes zoster ( hz ) , and postherpetic neuralgia ( phn ) is a frequent complication occurring in 5% to 15% of cases , causing moderate to severe neuropathic pain . a population - based observational study was conducted to evaluate the treatment patterns and econom...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : an important goal of visual system studies in animals is to understand vision in humans . in past decades , emphasis has been placed on studying c...
### Summary: : previous studies in rabbits identified an array of extrastriate cortical areas anatomically connected with v1 but did not describe their internal topography . to address this issue , we injected multiple anatomical tracers into different regions in v1 of the same animal and analyzed the topography of r...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the surgical extraction of an impacted mandibular third molar is one of the most common procedures performed by oral and maxillofacial surgeons . ...
### Summary: : impacted mandibular third molars are located between the second mandibular molar and mandibular ramus . however , ectopic mandibular third molars with heterotopic positions are reported in the subcondylar or pterygomandibular space . the usual cause of malposition is a cyst or tumor , and malpositi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cardiovascular disease ( cvd ) is leading to mortality among patients who were in developed countries . in the early of 20 century , < 10% of the wo...
### Summary: : background : dietary diversity score ( dds ) measurement was used to assessment of diet quality in different disease like cardiovascular disease . one way to improve the cardiovascular patient 's ability is cardiac rehabilitation program that include exercise training , nutrition consultation and psy...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : congenital candidiasis ( cc ) is rare and usually caused by intrauterine candidial infection and manifests within first 6 days of life . it may be...
### Summary: : congenital candidiasis ( cc ) is a rare disease with less than 100 cases being reported in the literature . it presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress , sepsis , and death . we report a neon...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : epiretinal membrane ( erm ) formation reflects a number of pathological changes occurring in vitreoretinal junctions . retinal glial cells , fibrous...
### Summary: : purpose . to assess functional and morphological alterations following video - documented surgery for epiretinal membranes . methods . forty - two patients underwent video - documented 23-gauge vitrectomy with peeling of epiretinal ( erm ) and inner limiting membrane ( ilm ) . patient assessment ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : this is an institutional review board ( irb ) approved retrospective sequential review of case notes and x - rays of all children admitted to our in...
### Summary: : backgroundthe management of the pulseless perfused hand in association with a supracondylar humerus fracture following operative stabilisation remains controversial . previous authors have suggested the use of color - flow duplex monitoring , magnetic resonance angiography and segmental pressure mo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : motor branch or recurrent branch of the median nerve , also called as the thenar branch , innervates the intrinsic muscles of the thumb ( abductor p...
### Summary: : we present a 62-year - old female patient who had an anatomic variation in the median nerve of the left hand . during surgery for releasing the left carpal tunnel , an abnormally high level of origin of the thenar muscular branch of the median nerve was detected , at 2.5 cm above the proximal border ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : catatonia was first described by kahlbaum in 1874 , as a brain disorder , which has cyclic , alternating and progressive course . over the years ,...
### Summary: : there is lot of skepticism about the use of electroconvulsive therapy ( ect ) in children and adolescents . however , available literature suggests that use of ect can be at times life - saving in adolescents , especially those presenting with severe catatonia . we treated a 16-year - old female wh...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 15-year - old female developed fever , stinging eyes and headache , followed one day later by sudden appearance of flaccid blisters on the face wi...
### Summary: : toxic epidermal necrolysis is a rare but clinically well - described dermatological pathology . however , clinical pictures of this disorder in text books do not reflect its dynamic evolution . usually , the desquamative post - bullous stage is represented , neglecting the initial bullous stage as ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : neuroepithelial cells , which constitute the wall of the neural tube , proliferate by repeating symmetric cell division , where each neuroepithelial...
### Summary: : in neural stem / progenitor cells , expression of the notch effector hes1 , a transcriptional repressor , oscillates with a period of 23 h by negative feedback , and hes1 oscillations induce the oscillatory expression of the proneural gene neurogenin2 ( ngn2 ) and the notch ligand gene delta - like1 (...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : urinary bladder metastasis from solid tumors is rare and represents 2% of all bladder neoplasms . direct extension from the cervix , prostate and ...
### Summary: : breast carcinoma is the most common nondermatologic cancer diagnosis in women . common metastatic sites include lymph nodes , lung , liver , and bone . breast carcinoma metastatic to the bladder has been reported only sporadically . most patients were symptomatic breast cancer with evidence of di...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the events of 11 september 2001 , and the subsequent mailings of anthraxladen envelopes within the usa , forever changed the way americans view publ...
### Summary: : summarydespite substantial investments since the events of 2001 , much work remains to prepare the nation for a chemical , biological , radiological or nuclear ( cbrn ) attack or to respond to an emerging infectious disease threat . following a 2010 review of the us public health emergency medical co...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hiv-1 associated neurocognitve disorders ( hand ) commonly follow progressive virus infection in the infected human host.(1 ) clinical disease featu...
### Summary: : regulatory t cells ( treg ) induce robust neuroprotection in murine models of neuroaids , in part , through eliciting anti - inflammatory responses for hiv-1-infected brain mononuclear phagocytes ( mp ; macrophage and microglia ) . herein , using both murine and human primary cell cultures in proteomic...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : exposed root surfaces in the anterior region may have several consequences : impaired aesthetics , increased risk of root caries , and hypersensitiv...
### Summary: : purpose . the aim of this prospective longitudinal clinical pilot study was the evaluation of the effect on the oral health impact profile ( ohip ) and patient - centered results of the envelope technique for connective tissue graft ( ctg ) . methods . sixteen patients ( 11 females ) 24 to 71 yea...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : rosette forming glioneuronal tumor ( rgnt ) a rare slowly growing tumor affecting mainly the young adults which has been included as one of the glio...
### Summary: : rosette forming glioneuronal tumor ( rgnt ) is a recently recognized and extremely rare glioneuronal tumor occurring in the fourth ventricle . it is crucial for the cytopathologist to be aware of this entity as it can be easily mistaken for more common neoplasms occurring at this site . we present ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : disability due to chronic pain ( dcp ) results in absence from work and is a major public health concern in japan and many western countries.14 vari...
### Summary: : objectivethe generic start back 5-item screening tool ( start - g ) is used to manage chronic pain in the lower back and elsewhere . this study evaluated the validity of the japanese version of this generic screening tool.materials and methodsjapanese participants between the ages of 20 and 64 years ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : these comorbidities might lead to the overuse or misuse of antipsychotic drugs , which has been suggested to increase mortality in this patient popu...
### Summary: : abstract objectives : to evaluate the effects of diffused lavender on the frequency of behavioral issues [ bis ] , defined as a composite of restlessness / wandering [ rw ] , agitation [ agt ] , anger [ ang ] , and anxiety [ anx ] in an adult day care center . secondary objectives evaluate systemat...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the main public health strategy for containing influenza is annual vaccination , which is recommended for the elderly and others belonging to risk -...
### Summary: : summarythe main public health strategy for containing influenza - related disease is annual vaccination , which is recommended for the elderly and others belonging to risk - factor categories , who present the highest morbidity and mortality , as reported by the world health organization ( who ) recomm...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : twelve wistar strain male rats , aged 120 days and with a mean weight of 250 to 300 g , were obtained from the breeding center of the anatomical and...
### Summary: : many research studies report the healing effects of aloe vera , thyroid hormone cream and silver sulfadiazine . however , the effects of these therapeutic agents are not well understood and have not been compared in one study . this study aimed at investigating the effects of topical application of...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : antibiotics are well known to alter neuronal functioning , with penicillin being the best studied on not only a clinical level but on a basic scienc...
### Summary: : a 66-year - old male receiving intravenous piperacillin and nafcillin for a post - surgical wound infection developed intermittent myoclonic jerks of all four extremities that disappeared after discontinuation of these two medications . in addition there was a mild yet definite intermittent encephalo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : pain is defined as an unpleasant sensory and emotional experience arising from any part of the body . it is associated with actual or potential ti...
### Summary: : pain is an unpleasant experience and effects daily routine negatively . although there are various drugs , many of them are not entirely successful in relieving pain , since pain modulation is a complex process involving numerous mediators and receptors . therefore , it is a rational approach to iden...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : shafer in 1983 introduced the term ameloblastic carcinoma ( ac ) to describe ameloblastomas in which there had been histological malignant tra...
### Summary: : abstractbackgroundthe aim of the present article is to report a case of ameloblastic carcinoma and use a marker alpha smooth muscle actin as a tool to differentiate cases of ameloblastic carcinoma from that of ameloblastoma.methodscase study reporting a case of ameloblastic carcinoma ( ac ) with ex...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : near - infrared spectroscopy ( nirs ) offers a new monitoring tool to be used in critically ill patients . nirs measures the saturation of hemoglo...
### Summary: : introductionthe purpose of the present review is to review our experience with near - infrared spectroscopy ( nirs ) monitoring in shock resuscitation and predicting clinical outcomes.methodsthe management of critically ill patients with goal - oriented intensive care unit ( icu ) resuscitation continu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : post - kala - azar dermal leishmaniasis ( pkdl ) is a dermal manifestation of leishmania donovani infection and often follows resolution of clinical...
### Summary: : background . post - kala - azar dermal leishmaniasis ( pkdl ) plays an important role in maintaining endemicity of visceral leishmaniasis and its transmission . treatment regimens for pkdl are toxic and require 3 - 4 months of hospitalization . these long and arduous regimens result in extensive ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : alopecia areata ( aa ) is common cause of reversible hair loss afflicting approximately 1 to 2% of the general population . a wide range of clinic...
### Summary: : background : alopecia areata ( aa ) is a common form of localized , nonscarring hair loss . it is characterized by the loss of hair in patches , total loss of scalp hair ( alopecia totalis , at ) , or total loss of body hair ( alopecia universalis , au ) . the cause of aa is unknown , although most evi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the benguela upwelling system ( bus ) along the southwest african continental margin is one of the most productive upwelling regions in the world oc...
### Summary: : summarysediments across the namibian continental margin feature a strong microbial activity gradient at their surface . this is reflected in ammonium concentrations of < 10 m in oligotrophic abyssal plain sediments near the south atlantic gyre compared with ammonium concentrations of > 700 m in u...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the use of nanoparticles for cellular imaging is among the most important clinical breakthrough of the past decade . in particular , superparamagnet...
### Summary: : purposemagnetic resonance imaging ( mri ) using contrast agents like superparamagnetic iron oxide ( spio ) is an extremely versatile technique to diagnose diseases and to monitor treatment . this study tested the relative importance of particle size and surface coating for the optimization of mri con...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : leptin deficiency or dysfunction is one of the main causes for insulin resistance ( ir ) and lipid metabolism disorders [ 1 , 2 ] . it has been fo...
### Summary: : aim . to investigate the effects of acute and chronic exercise on glucose and lipid metabolism in liver of rats with type 2 diabetes caused by a high fat diet and low dose streptozotocin ( stz ) . methods . animals were classified into control ( con ) , diabetes ( dc ) , diabetic chronic exercise (...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : canine ehrlichiosis , a tick borne disease , was first recognized by donatien and lestoquar ( 1935 ) and has since been reported in dogs geographica...
### Summary: : background : the aims of this study were to determine the seroprevalence of canine ehrlichiosis and risk factors of this disease in companion dogs population of mashhad , north east of iran . canine monocytic ehrlichiosis ( cme ) is a zoonotic disease transmitted by ticks , rhipicephalus sanguineus ,...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : zhigancao , glycyrrhizae radix et rhizoma praeparata cum melle , originates from the processed dried roots or rhizomes of glycyrrhriza uralensis fis...
### Summary: : a sensitive hplc method was developed for the quantitative determination of isoliquiritin apioside ( ila ) and isoliquiritin ( il ) in rat plasma . after protein precipitation with acetonitrile , chloroform was used to separate lipid - soluble impurities from the plasma samples and remove acetonitril...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : consumption of green tea is inversely associated with risk for cardiovascular diseases and stroke,1 as well as with lower cardiovascular and total m...
### Summary: : abstract : the underlying mechanisms for the vasodilating effects of the tea catechin epigallocatechin-3-gallate ( egcg ) are still not fully understood . besides nitric oxide ( no)-dependent effects , other modes of action are discussed . to elucidate whether the no pathway is a prerequisite in medi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : indeed , the ten leading companies newly marketed compounds increased their revenues by only ~10 % , and the average innovation deficit was ~1.31...
### Summary: : with a predicted 382.4 per 100,000 people expected to suffer from some form of malignant neoplasm by 2015 , and a current death toll of 1 out of 8 deaths worldwide , improving treatment and/or drug design is an essential focus of cancer research . multi - drug resistance is the leading cause of chemo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the anterior cruciate ligament ( acl ) is one of major knee ligaments and is critical to knee stability . injury to the acl can be a debilitating ...
### Summary: : background : reconstruction of the anterior cruciate ligament ( acl ) involves use of semintendinosis and gracilis tendons graft that is transplanted into bone tunnels at the femoral and tibial insertion sites and the sites and the bone tendon interface is a weak link in the early healing period due to...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : over the past year , multiple noteworthy trials with the potential to evolve current clinical practice and guidelines have been presented at interna...
### Summary: : introductionmultiple significant , potentially practice changing clinical trials in cardiology have been conducted and subsequently presented throughout the past year.methodsin this paper , the authors have reviewed and contextualized significant cardiovascular clinical trials presented at major intern...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : non - alcoholic fatty liver disease ( nafld ) is a major cause of chronic liver disease globally , and is characterized by a spectrum of steatosis ,...
### Summary: : abstractnon - alcoholic fatty liver disease ( nafld ) and non - alcoholic steatohepatitis ( nash ) are national and global epidemics . the disease is characterized by a spectrum of liver steatosis ( fat deposition ) , inflammation ( in nash ) and fibrosis . nafld and specifically nash can lead to c...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : type 2 diabetes ( t2d ) is the most common form of diabetes and an increasingly prevalent metabolic disease . it is associated with microvascular ...
### Summary: : aims . the polymorphisms of pro- and anti - inflammatory cytokines may be involved in type 2 diabetes ( t2d ) pathogenesis and its complications . methods . we investigated in 102 t2d patients the association of the cytokine polymorphisms in the tnf- , il-10 , il-6 , tgf-1 , and ifn- genes with t...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : down syndrome ( ds ) is one of the most frequent congenital disorders in humans . many of them develop symptoms of alzheimer s disease ( ad ...
### Summary: : the protein kinase dyrk1a has been suggested to act as one of the intracellular regulators contributing to neurological alterations found in individuals with down syndrome . for an assessment of the role of dyrk1a , selective synthetic inhibitors are valuable pharmacological tools . however...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : world - wide , 13 million people develop sepsis each year , and as many as 4 million people have died . in 1996 , there were 4.774 patients admitted...
### Summary: : background : the appropriate selection of empirical antibiotics based on the pattern of local antibiotic resistance can reduce the mortality rate and increase the rational use of antibiotics.aims:we analyze the pattern of antibiotic use and the sensitivity patterns of antibiotics to support the rationa...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : daytime running lights ( drls ) are a safety feature intended to reduce crashes by increasing the contrast between vehicles and the background . c...
### Summary: : backgrounddaytime running lights ( drls ) are a safety feature intended to reduce crashes by increasing the contrast between vehicles and the background.aimsthe purpose of this study was to determine whether there is an association between vehicles in the usa being equipped with drls and crash rates.me...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although prostate cancer is the second leading cause of cancer - related deaths in men in the us , early detection with serum prostate - specific an...
### Summary: : the presence of two or more prostate cancer foci separated by intervening benign tissue in a single core is a well - recognized finding on prostate biopsy . cancer involvement can be measured by including intervening benign tissue or only including the actual cancer involved area . importantly , th...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the leptomeninges are composed of the pia and arachnoid mater connected by strands termed arachnoid trabeculae . in the young , the leptomeninges ...
### Summary: : objectivesnotwithstanding the lack of definitive evidence from studies conducted to date , inflammatory infiltrates and iron deposition in the leptomeninges are routinely used as forensic markers of traumatic brain injury . we investigated the presence of these forensic markers of trauma in neonates ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : their occurrence was first described in 1670 by thilesus . however , at that time fistulas were a common complication of chronic and untreated chole...
### Summary: : cases of cholecystocutaneous fistulas are now a rare occurrence as a result of rapid diagnosis and treatment . we present a case of cholecystocutaneous fistula developing after the removal of a percutaneous drain for the treatment of acute cholecystitis . re - occurring infection and presence of ga...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : tropical fevers are defined as infections that are prevalent in or are unique to tropical and subtropical regions . they occur in different parts ...
### Summary: : we report a case of ciprofloxacin - related drug rash with eosinophilia and systemic symptoms ( dress ) which was initially diagnosed and managed on the line of tropical fever . later , a diagnosis of definite case of dress was made according to the regiscar scoring system and the patient was managed...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : angiogenesis , the formation of new vessels from existing vessels , plays an important role in pathological conditions in various organs . patholo...
### Summary: : retinal pathogenic angiogenesis in the eyes is a causative factor in retinopathy of prematurity , diabetic retinopathy , and age - related macular degeneration . this study was designed to examine the pathogenic role of the high - mobility group box-1 ( hmgb1 ) protein and the inhibitory effect of et...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : smallholder agriculture in semiarid areas is hampered by accelerated soil erosion , induced soil moisture deficits , soil fertility depletion , and ...
### Summary: : a field study was carried out to evaluate the effects of tillage practices on soil physical properties in mwala district , eastern kenya , during the long rains ( lr ) and short rains ( sr ) of 2012/13 . the treatments were disc ploughing ( dp ) , disc ploughing and harrowing ( dph ) , ox - ploughing...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : pregabalin ( pg ) chemically is 3-amino methyl hexanoic acid , with the chemical formula c8h17no2 . its structural and pharmacological features co...
### Summary: : this paper demonstrates colorimetric visible spectrophotometric quantification methods for amino acid , namely , tranexamic acid and pregabalin . both drugs contain the amino group , and when they are reacted with 2,4-dinitrophenol and 2,4,6-trinitrophenol , they give rise to yellow colored complexes...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : world health organization and unaids report about 39.5 million hiv - infected people worldwide and about 2 million people in latin america . in 2009...
### Summary: : backgroundthe highly active antiretroviral therapy ( haart ) has altered the course of hiv infection , transforming it from a fatal illness to a chronic condition , reducing morbidity and mortality . however , this therapy has led to an increased incidence of metabolic problems such as insulin resist...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the jichi medical school ( jms ) cohort study is a prospective , population - based study aimed at exploring the risk factors for cvd in 12 communit...
### Summary: : objectiveto examine the bmi - stratified associations between diabetes and the risks of all - cause death , cardiovascular disease ( cvd ) death , and cancer death.research design and methodsusing a prospective study with 12 rural japanese general populations ( n = 3,641 , mean age , 53.7 years ; 33.5%...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : approximately 26% of american adults are suffering from a diagnosable mental disease , and nearly half ( 45% ) of them meet criteria for two or more...
### Summary: : depression , the most common type of mental illness , is the second leading cause of disability and is increasing among americans . the effect of improved nutrition , particularly with dietary supplements , on depression may provide an alternative to standard medical treatment . some studies have s...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : reed 's syndrome refers to the onset of uterine leiomyomas with cutaneous leiomyomas , the latter occurring segmentally or affecting a particular de...
### Summary: : reed 's syndrome or familial myomatosis cutis et uteri , an autosomal dominant inherited condition with incomplete penetrance , is characterized by multiple cutaneous and uterine leiomyomas.[1 ] uterine leiomyomas usually commence earlier compared to that in the general population and cutaneous leiomyo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : dna double - strand breaks are extremely toxic dna lesions that arise from a variety of sources , including ionizing radiation , radiomimetic drugs ...
### Summary: : most dna double - strand breaks ( dsbs ) formed in a natural environment have chemical modifications at or near the ends that preclude direct religation and require removal or other processing so that rejoining can proceed . free radical - mediated dsbs typically bear unligatable 3-phosphate or 3-pho...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 65-year - old man with a medical history of stage iii nasopharyngeal cancer , end - stage renal disease treated with dialysis , hyperthyroidism , ...
### Summary: : mnckeberg sclerosis is a disease of unknown etiology , characterized by dystrophic calcification within the arterial tunica media of the lower extremities leading to reduced arterial compliance . medial calcinosis does not obstruct the lumina of the arteries , and therefore does not lead to symptoms ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cerebral palsy includes a group of nonprogressive movement disorders due to brain lesions or abnormalities in early development . its prevalence o...
### Summary: : objective . to identify the risk factors for cystic periventricular leukomalacia ( cpvl ) and their implications for deciding between immediate delivery and conservative management of preterm prelabor rupture of the membranes ( pprom ) . methods . the following risk factors were compared between cp...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the belgian pharmacologist bacq discovered the existence of toxins in nemertines during the mid- 1930s while searching for invertebrate neurotransmi...
### Summary: : nemertines are a phylum of carnivorous marine worms that possess a variety of alkaloidal , peptidic or proteinaceous toxins that serve as chemical defenses against potential predators . the hoplonemertines additionally envenomate their prey with a mixture of proboscis alkaloids delivered with the hel...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : recent work has demonstrated the importance of the abdominal muscles in ensuring sufficient spine stability to prevent buckling and enhance func...
### Summary: : [ purpose ] the purpose of this study was to investigate the effects of the abdominal hollowing exercise on trunk muscle activity during the curl - up exercise on an unstable surface by measuring electromyography ( emg ) activity . [ subjects ] fourteen young healthy adults ( nine male , five f...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : to report the ultrasound biomicroscopy ( ubm ) and surgical findings in a subject with a syndrome of ectopia lentis , spontaneous filtering blebs , ...
### Summary: : purposeto report the ultrasound biomicroscopy ( ubm ) and surgical findings in a subject with a syndrome of ectopia lentis , spontaneous filtering blebs , and craniofacial dysmorphism ( traboulsi syndrome).methodscase report , using a 40-mhz ubm wide - field anterior segment scan and anterior segment o...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : normally , maintenance of the intestinal epithelium involves a dynamic process in which intestinal stem cells ( iscs ) located at the crypt base und...
### Summary: : inflammatory bowel disease ( ibd ) is characterized by dysregulated immune responses to the intestinal microbiota , and by chronic intestinal inflammation . several recent studies demonstrate the importance of innate microbial recognition by immune and nonimmune cells in the gut . paradoxically , e...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although proinflammatory effects of acute hyperglycemia in inflammatory conditions and septic patients have been extensively investigated in clinica...
### Summary: : it is well acknowledged that proinflammatory stimulation during acute hyperglycemia is able to aggravate inflammatory diseases . however , the mechanisms of proinflammatory effects of glucose are controversially discussed . we investigated leukocyte recruitment after intravenous injection of glucos...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : for several decades there has been a demographic shift towards an ageing population taking place across the european continent , albeit at varying s...
### Summary: : this paper is an examination of the recent restructuring and subsequent convergence of european long - term care models . this paper also aims to highlight the increased role of migrant care workers and the need for great social and governmental recognition for all care providers . the provision of...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cloacogenic carcinomas ( ccs ) are relatively common neoplasms of the anal canal and are thought to arise from cloacogenic remnants at this site . ...
### Summary: : cloacogenic carcinoma ( cc , basaloid carcinoma ) generally occurs around the dentate line , rarely it can arise from the other sides of the colon . there are only 5 cases of cc located outside the anal canal in the literature . the first occurrence of a cc presents as intraabdominal abscess . we...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : gastric antral vascular ectasia ( gave ) is a rare disorder associated with chronic upper gastrointestinal bleeding that mainly affects elderly wome...
### Summary: : gastric antral vascular ectasia ( gave ) is currently recognized as an important cause of gastrointestinal bleeding . chronic kidney disease ( ckd ) is associated with a high incidence of gave . we report 3 patients with ckd who presented with severe anemia and were diagnosed with gave ; they were re...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : wilms tumor is the most common primary malignant renal tumor in children , accounting for 6% of all pediatric malignant tumors 1 , however , it is v...
### Summary: : wilms tumor ( wt ) occurs infrequently in adults . even rarer is adult wt with extension by direct intravascular spread into the right side of the heart . the present report describes a partially differentiated wt with intracaval and intracardiac extension in a 54-year - old man . the morphologic...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : many studies provide evidence pointing to a clear role of vitamin d in the pathogenesis of autoimmune diseases , especially autoimmune thyroid disea...
### Summary: : objectives . some evidence has pointed out that vitamin d plays a significant role in reducing the incidence of autoimmune diseases , especially autoimmune thyroid diseases . the authors aimed to examine the relationship between circulating 25-hydroxyvitamin d and thyroid autoantibody in a population...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : asthma and copd have been regarded as two distinct disease entities that often overlap.13 asthma and copd overlap has a prevalence of 15%20% in pati...
### Summary: : backgroundthe clinical phenotypes and underlying mechanisms of asthma - copd overlap syndrome ( acos ) remain elusive . this study aimed to investigate a comparison of copd patients with and without acos , focusing on inflammatory biomarkers , in an outpatient copd cohort.methodswe conducted a cross ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : porcine parvovirus ( ppv ) , first isolated from sows in germany , has been found to occur worldwide [ 24 ] . this syndrome is characterized by st...
### Summary: : porcine parvovirus ( ppv ) is a widespread infectious virus that causes serious reproductive diseases of swine and death of piglets . the gene coding for the major capsid protein vp2 of ppv was amplified using viral nucleic acid extract from swine serum and inserted into yeast saccharomyces cerevisia...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the prevalence of as ranges from 2% to 9% of aged population over 65 years old , and it is increasingly diagnosed in the contemporary era of aging s...
### Summary: : backgroundaortic stenosis ( as ) is increasingly diagnosed in current aging society . echocardiography is the most important tool in the assessment of as and its severity . however , load - dependency of doppler measurement could affect the accuracy of as severity assessment . we tried to evaluat...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : migraine is typically characterized by a pulsating headache with or without aura , nausea , and vomiting . the drugs commonly used in acute migrai...
### Summary: : introductionthis case report adds supportive evidence to the development of acute angle - closure glaucoma ( aacg ) , a rare but serious adverse effect following the use of topiramate ( tpm ) for a severe headache.case reporta 25-year - old female reported with severe headache , suspected to be migrain...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the data from the articles by goldstein et al . suggest that both cardiologists and their patients tend to think that once a device such as an icd i...
### Summary: : as implantable cardioverter defibrillators ( icds ) have become more common , ethical issues have arisen regarding the deactivation of these devices . goldstein et al . , have shown that both patients and cardiologists consider icd deactivation to be different from the discontinuation of other life -...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : total joint arthroplasty , in particular tha , has had a revolutionary role in improving the quality of life . the use of bone cement for the impl...
### Summary: : background : cementless hip prosthesis was designed to provide biologic fixation , without the use of cement . the second generation components have shown more reliable bone ingrowths and survival rates . we are reporting a midterm result of two designs of cementless prosthesis in a unique culture ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : noninvasive prenatal testing ( nipt ) is becoming increasingly popular in the united states , with increasing advocacy in the medical community . so...
### Summary: : key clinical messagenoninvasive prenatal testing ( nipt ) is becoming increasingly popular with some offering it as a primary screen option in all patients in place of serum screening . serum screening offers insight into placental function , which nipt does not . abnormal levels of analytes in the...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : common placebos are usually inert tablets or sham surgery based on false information . since the publication of henry k. beecher 's in 1955 , the ...
### Summary: : a placebo is a sham medical intervention that can produce a placebo effect . laboratory evidence supports the existence of several mechanisms of placebo effects in both healthy population and patients with a variety of medical conditions . the ethics of placebos have long been debated . however , a...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : prior to the genome era , compositional signatures ( 1 ) or sequence alignments ( 2 ) were used to delineate the phylogenetic patterns across organi...
### Summary: : species evolutionary relationships have traditionally been defined by sequence similarities of phylogenetic marker molecules , recently followed by whole - genome phylogenies based on gene order , average ortholog similarity or gene content . here , we introduce genome conservation a novel metric of...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hyperplasia refers to tissue growth into the oral cavity , located over the alveolar ridges or the soft tissues of the vestibular sulcus . its eti...
### Summary: : the aim of this study was to present a case report of the surgical removal of hyperplasia in the oral cavity , using carbon dioxide ( co2 ) laser radiation and rehabilitation with a complete denture . epulis fissuratum occurs in complete denture patients , because a constant irritative action induces...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : there is much controversy regarding the use and timing of enteral feeding support in patients with dysphagia and aspiration risk . the decision pr...
### Summary: : purposeover 4.5 million people in north america had a diagnosis of dementia in the year 2000 , and more than half had advanced disease with potential aspiration risk . there is much controversy regarding the use and timing of enteral feeding support in these patients with dysphagia . the management...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : bone dysplasias are characterized by the replacement of normal bone with fibrous tissue containing abnormal bone or cementum.1 familial gigantiform ...
### Summary: : ehlers - danlos syndrome is an autosomal dominant hereditary disorder of connective tissue , while familial gigantiform cementoma is a condition that usually manifests as multiple radiopaque cementum - like masses throughout the jaws . this case report discusses the oral management and prosthetic reh...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cervical cancer is a major health challenge with approximately 530,000 news cases and 270,000 deaths annually worldwide despite remarkable advances ...
### Summary: : cervical cancer epitomizes the success of cancer prevention through the human papillomavirus ( hpv ) vaccine , but significant challenges remain in the treatment of advanced disease . we report the first three cases of cervical carcinoma harboring an fgfr3tacc3 fusion , which serves as a novel therap...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : anca - associated vasculitides ( aav ) are autoimmune diseases characterized by inflammation of the blood vessel wall and include microscopic polyan...
### Summary: : objective . st2 , a member of the interleukin-1 receptor family , is selectively expressed on th2 cells and mediates important th2 functions . il-33 is a specific ligand of st2 . the aim of the study was to determine whether serum levels of soluble st2 ( sst2 ) or il-33 predict activity of the di...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : atherosclerotic disease of the coronary arteries is one of the most common causes of mortality and morbidity . despite all the methods of diagnosis ...
### Summary: : background : atherosclerotic disease is the most important cause of mortality in the world . oxidation is an important pathway in the pathogenesis of coronary artery disease ( cad ) through oxidation of low - density lipoprotein ( ldl ) and free radical formation . copper ( cu ) is an essential mic...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : coccygodynia , first described by simpson in 1859 , is disabling pain in the coccyx that is usually provoked by sitting or changing from a sitting t...
### Summary: : objectivea review of the literature on coccygectomy and our patients was performed to assess the effectiveness of coccygectomy for chronic refractory coccygodynia.methodsan english language pubmed search was conducted with the terms " coccygodynia " and " coccygectomy " from january 1980 to january 201...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 29-year - old woman with marfan 's syndrome was scheduled to undergo the elective bentall 's operation and thoracic aortic replacement with artifi...
### Summary: : hemothorax is a possible immediate complication of central venous catheterization . we experienced a patient who suffered from massive hemothorax 72 hours after right subclavian venous catheterization . a 29-year - old female patient with marfan 's syndrome underwent the bentall 's operation and ao...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the aim of this study was to identify the definition , therapeutics , and mechanism of diabetes from the resources of itm in order to provide new re...
### Summary: : background : diabetes mellitus is a complex disorder of carbohydrate metabolism . according to past studies , the word ziabites in iranian traditional medicine ( itm ) correlate with diabetes . the aim of this study was to identify the definition , therapeutics , and mechanism of diabetes from the re...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : recent advances in computer hardware and software have greatly extended the time scales that can be covered by biomolecular simulations . these ...
### Summary: : recent advances in computer hardware and software have made rigorous evaluation of current biomolecular force fields using microsecond - scale simulations possible . force fields differ in their treatment of electrostatic interactions , including the formation of salt bridges in proteins . ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : depression is a common mental disorder , with an estimated global burden of 350 million . lifetime prevalence rates range from approximately 3% to...
### Summary: : introduction : early diagnosis and management of depression is important for better therapeutic outcome . strategies for distinguishing between unipolar and bipolar depression are yet to be defined , resulting improper management . this study aims at comparing the socio - demographic and other variab...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : stroke is defined as rapidly developing symptoms and/or signs of focal and global loss of cerebral function lasting for at least 24 hours with no ap...
### Summary: : backgroundchanges in the lipid profile have been suggested as a risk factor for developing ischemic stroke . their role in intra - cerebral hemorrhage , however , is not clear . the present study was designed to evaluate the lipid profile levels of patients who had experienced an acute stroke durin...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : attendances to emergency departments due to accidental digital auto - injection of adrenaline seem to be on the rise . for every 50000 epipen unit...
### Summary: : after the accidental injection of epinephrine into a digit , various techniques to try and reverse the ensuing ischaemia were unsuccessful . to identify a further treatment strategy and as members of the admitting team were unfamiliar with digital injection of epinephrine a google search was performed ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : managed care is increasingly becoming a preferred administrative vehicle for states to control their medicaid budgets and assure access to and coord...
### Summary: : managed care now serves 23 percent of the medicaid population . with the shift to capitation , the fee - for - service ( ffs ) billing mechanism that has generated much of the administrative data used in policy planning and research no longer exists . this article provides an overview of the types of...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : dna , with its building block dna bases that store the genetic information , is indispensable in protein biosynthesis . investigations on long -...
### Summary: : the kinetics of triplet state quenching of 3,3,4,4-benzophenone tetracarboxylic acid ( bptc ) by dna bases adenine , adenosine , thymine , and thymidine has been investigated in aqueous solution using time - resolved laser flash photolysis . the observation of the bptc ketyl radical anion at ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : when angiotensin - converting enzyme-2 ( ace2 ) was serendipitously discovered ten years ago , neither of the two groups at the centre of its discov...
### Summary: : the renin - angiotensin system ( ras ) is a critical regulator of hypertension , primarily through the actions of the vasoactive peptide ang ii , which is generated by the action of angiotensin - converting enzyme ( ace ) m...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : with attention to the role of diet or medical nutritional therapy on chronic disease , the dietary pattern approach , which involves diet quality in...
### Summary: : the present study was performed to evaluate the relationship between dietary quality indices including the diet quality index - international ( dqi - i ) , alternate healthy eating index ( ahei ) , and healthy diet indicator ( hdi ) and glycemic status in korean patients with type 2 diabetes . a tota...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the cath database is a hierarchical classification of domains into sequence- and structure - based families and fold groups . table 1 shows the po...
### Summary: : the cath database of protein domain structures ( http://www.biochem.ucl.ac.uk/bsm/cath/ ) currently contains 43 229 domains classified into 1467 superfamilies and 5107 sequence families . each structural family is expanded with sequence relatives from genbank and completed genomes , using a variety ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a literature search of the pubmed online database was carried out to identify studies that reported the causes of death after tavr on august 10 , 20...
### Summary: : backgroundtranscatheter aortic valve replacement ( tavr ) is an effective alternative to surgical aortic valve replacement in patients at high surgical risk . however , there is little published literature on the exact causes of death.methods and resultsthe pubmed database was systematically searched...