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<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the synthesis methods and the use of nanostructures for various applications have been a very lucrative topic in the last decade .
these efforts h... | ### Summary:
: the phenomenon of persistent photoconductivity is elusive and has not been addressed to an extent to attract attention both in micro and nanoscale devices due to unavailability of clear material systems and device configurations capable of providing comprehensive information . in this work ,
we have ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: they produce mature progenies to replace short - lived cells and repair tissue damage while maintaining their numbers through self - renewing divisi... | ### Summary:
: summarythe activity of adult stem cells is regulated by signals emanating from the surrounding tissue .
many niche signals have been identified , but it is unclear how they influence the choice of stem cells to remain quiescent or divide . here we show that when stem cells of the adult hippocampus re... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: methods and any associated references are available in the online version of the paper at http://www.nature.com / naturemedicine/.
| ### Summary:
: t - cell acute lymphoblastic leukemia ( t - all ) is an immature hematopoietic malignancy driven mainly by oncogenic activation of notch1 signaling1 . in this study
we report the presence of loss - of - function mutations and deletions of ezh2 and suz12 genes , encoding critical components of the pol... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: elimination of vertical transmission of hiv is a global priority , yet progress remains marred by severe disparities across regions . while it is al... | ### Summary:
: introductionnumerous barriers to optimal uptake of prevention of mother to child transmission ( pmtct ) services occur at community level ( i.e. , outside the healthcare setting ) . to achieve elimination of paediatric hiv , therefore
, interventions must also work within communities to address these... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: restoration of a tooth with extensive destruction may require a post to retain the restorative material securely and promote an even distribution of... | ### Summary:
: purposethe aim of this in vitro study was to evaluate the mechanical properties ( bending strength and hardness ) of seven different fiber reinforced composite posts , in relation to their microstructural characteristics.materials and methodstwo hundred eighty posts were divided into seven groups of 40... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: | ### Summary:
: additional -globin genes in sheep might produce extra -globin chains and , consequently , the subject carrying triplicated ( ) or quadruplicated ( ) haplotypes may exhibit different hematological phenotypes when compared to the normal duplicated ( ) homozygotes ( nn ) . both and heterozygous ( nd ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: diabetes mellitus is a growing health problem worldwide causing severe and costly complications including blindness , cardiac and kidney diseases ( ... | ### Summary:
: objective(s):ethnopharmacological field surveys demonstrated that many plants , such as gentiana olivieri , helichrysum graveolens , helichrysum plicatum ssp .
plicatum , juniperus oxycedrus ssp .
oxycedrus , juniperus communis var .
saxatilis , viscum album ( ssp .
album , ssp .
austriacum )... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the incidence of malignant melanoma has been increasing by 2.6% annually over the last decade , with approximately 76,790 new cases resulting in 9,4... | ### Summary:
: melanoma is a malignancy of melanocytes or pigment - producing cells located predominantly in the skin .
it is less common than other skin cancers but causes the greatest number of skin cancer - related deaths worldwide .
the incidence of melanoma continues to increase and early detection is the mo... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: amblyopia is a developmental ocular disorder characterized by a unilateral or bilateral visual deficiency that is out of proportion with any structu... | ### Summary:
: amblyopia , which usually occurs during early childhood and results in poor or blurred vision , is a disorder of the visual system that is characterized by a deficiency in an otherwise physically normal eye or by a deficiency that is out of proportion with the structural or functional abnormalities of ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: to meet the wide variety of consulting needs that undergraduate neuroscience programs and departments have , the pdcs maintains a database of facult... | ### Summary:
: in 2007 fun established the fun program and department consultations service , or fun - pdcs . since that founding
, the service has provided numerous consultation recommendations to undergraduate programs seeking assistance with external program reviews , designing and improving courses and many oth... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: youth violence is a major international public health concern [ 1 , 2 ] . in nearly every region of the world ,
adolescents and young adults compr... | ### Summary:
: objective .
using nationally representative data , this study examined the prevalence of very frequent physical fighting ( 12 times per year ) among youth in 27 countries and cities .
frequent physical fighting has rarely been reported in the previous literature despite the implications for researc... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: forty patients with aphakia were randomized and allocated into anterior chamber ( group 1 ) and retropupillary implantation ( group 2 ) group .
gr... | ### Summary:
: purpose : to compare the outcomes of anterior chamber and retropupillary implantation of iris - claw artisan intraocular lenses ( iol).design : prospective , randomized , single - blinded study.patients and methods : forty eyes of forty aphakic patients were enrolled .
patients were randomized into t... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: ak is a 61-year - old woman who developed right upper quadrant pain and underwent a laparoscopic cholecystectomy on january 22 , 2013 .
operative ... | ### Summary:
: trastuzumab is a monoclonal antibody targeting her-2 .
her-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma .
this report describes the first case of a patient with her-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and bioc... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: proper functioning of the central nervous system requires a fine balance between excitatory and inhibitory neurotransmission .
cortical inhibitory... | ### Summary:
: cortical inhibitory neurons play crucial roles in regulating excitatory synaptic networks and cognitive function and aberrant development of these cells have been linked to neurodevelopmental disorders .
the secreted neurotrophic factor neuregulin-1 ( nrg1 ) and its receptor erbb4 are established reg... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: leishmaniasis is a vector - borne disease caused by obligate intramacrophage protozoan parasites of the genus leishmania [ 1 , 2 ] .
the infecting... | ### Summary:
: in an attempt to investigate the effects of treatment of human leishmaniasis , the cytokines produced by peripheral blood mononuclear cells ( pbmcs ) of patients with cutaneous leishmaniasis ( cl ) and mucocutaneous leishmaniasis ( mcl ) under treatment with amphotericin b were determined during the ac... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the off - label use of drugs in paediatrics , i.e. the prescription of drugs which are not licensed for a specific age or mode of application , is o... | ### Summary:
: off - label drug use in paediatrics is associated with an increased risk of adverse drug reactions . any risk benefit analysis has to be based on value judgments that should include parents ' views . however ,
nothing is known so far about the parents ' perspective on this critical issue . therefore... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: this was a cross - sectional questionnaire study conducted on 1514 participants , which included faculty mds and bds and pgs in 40 dental colleges o... | ### Summary:
: objective : research in the dental field is progressing at mightier speed worldwide , but an unfortunately representation of india at this platform is negligible .
the present study was undertaken to unearth the barriers for dental research among dental professionals in indian scenario.materials and ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: cervicitis is defined clinically by the presence of either mucopurulent discharge or easily induced bleeding at the endocervical os , more subtle si... | ### Summary:
: infection with genital herpes simplex virus ( hsv ) remains a common viral sexually transmitted disease , often subclinical and a major worldwide problem of women of reproductive age group .
herpes cervicitis is an unusual presentation of herpes simplex virus infection in females .
the finding of h... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: we developed an ordinary differential equation simulation model for hiv testing and treatment among msm in san francisco extending previous models [... | ### Summary:
: modeling of expanding antiretroviral treatment to all hiv infected adults already in care in san francisco predicts reductions in new hiv infections at 5 years of 59% among men who have sex with men ( msm ) .
addition of annual hiv testing for msm to universal treatment decreases new infections by 76... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the doctors said that it was puerperal fever and that it was ninety - nine chances in a hundred it would end in death . the whole day long there was... | ### Summary:
: sepsis is a major cause of mortality and morbidity in intensive care units .
organ dysfunction is triggered by inflammatory insults and tissue hypoperfusion .
the brain plays a pivotal role in sepsis , acting as both a mediator of the immune response and a target for the pathologic process .
the ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: dipeptidyl peptidase4 ( dpp4 ) inhibitors belong to a novel class of antidiabetic agents that increase the incretin hormones , glucagonlike peptide1... | ### Summary:
: abstract
( j diabetes invest , doi : 10.1111/j.20401124.2012.00221.x , 2012 )
aims / introduction : to determine the efficacy and safety of sitagliptin monotherapy and combination therapy in japanese type 2 diabetes patients after 3 months therapy.materials and methods : a retrospective , obs... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: complete decompression and reconstruction of the anterior and middle portions of the spine column are facilitated via anterior surgery , which is im... | ### Summary:
: background : subsidence and late fusion are commonly observed in anterior subtotal corpectomy and reconstruction for treating thoracolumbar burst fractures .
the subsidence rate of this surgical method was reported from 19.6% to 75% in the literatures , which would cause treatment failure .
thus , ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: abdominal obesity , characterized by preferential accumulation of intra - abdominal adipose tissue ( iat ) , contributes to cardiovascular and metab... | ### Summary:
: we have previously shown that physical activity predicts intra - abdominal adipose tissue ( iat ) , but it is unknown whether energy intake predicts iat independently of physical activity in a community - based , naturalistic environment .
the association of energy intake with iat was explored cross ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: primary carcinoma of the extrahepatic bile duct is a rare tumor that represents less than 1.0% of all malignant neoplasms and less than 3.0% of all ... | ### Summary:
: most malignant tumors originating from the biliary tract are adenocarcinomas , and adenosqamous carcinoma of klatskin 's tumor is a very rare finding .
an 83-yr - old man was admitted to our hospital because of jaundice . the abdominal computed tomography and magnetic resonance cholangiopancreatograp... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: microwave imaging has received significant attention in the research community during the last couple of decades as a modality that potentially coul... | ### Summary:
: nonlinear microwave imaging heavily relies on an accurate numerical electromagnetic
model of the antenna system .
the model is used to simulate scattering
data that is compared to its measured counterpart in order to reconstruct the image .
in this paper
an antenna system immersed in water is... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: imagine that you were asked to evaluate whether a new medicine produces an allergic
reaction as a side effect .
to accomplish this task , you ar... | ### Summary:
: abstract .
decades of research in causal and contingency learning
show that people s estimations of the degree of contingency between two
events are easily biased by the relative probabilities of those two events .
if
two events co - occur frequently , then people tend to overestimate the str... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the incidence of occupational disease in mo has increased during the past decade , after a downwards trend during the preceding years .
the incide... | ### Summary:
: objectiveswe aimed to describe how work exposure and occupational health is assessed for mine workers in murmansk oblast , russia.study designa descriptive study based on current practice , laws and available literature.methodsthe information and data were obtained from scientific publications , report... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: healthy volunteers were recruited from the general population of the delaware valley ( 10 ) .
the protocol was approved by the institutional revie... | ### Summary:
: objectivean emerging model of metabolic syndrome and type 2 diabetes is of adipose dysfunction with leukocyte recruitment into adipose leading to chronic inflammation and insulin resistance ( ir ) .
this study sought to explore potential mechanisms of inflammatory - induced ir in humans with a focus ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the surveyed races were flat races on turf and dirt tracks held by the jra from january 1st , 2002 , to december 31st , 2010 .
the race lengths we... | ### Summary:
: abstractthe running performance of thoroughbred racehorses has been reported to peak when they are between 4 and 5 years old .
however , changes in their racing speed by month or season have not been reported .
the purposes of this study were to reveal the average racing speed of thoroughbreds , an... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: thirty patients were diagnosed with iac in the peking union medical college hospital ( pumch ) from january 2011 to september 2014 , during which 27... | ### Summary:
: background and aim : immunoglobulin g4-associated cholangitis ( iac ) shares many similar symptoms with cholangiocarcinoma ( cca ) . however , the treatment and the prognosis are substantially different . this study aimed to identify the important markers for the differential diagnosis of these 2 disea... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the first core functionality of the laglidadg homing endonuclease database and engineering server ( lahedes ) resource is an updateable collection o... | ### Summary:
: laglidadg homing endonucleases ( lhes ) are dna cleaving enzymes , also termed
meganucleases that are employed as gene - targeting reagents .
this use of lhes requires that their dna specificity be altered to match sequences in genomic targets .
the choice of the most appropriate lhe to target a ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the art world changed forever in 1945 , the year that jackson pollock moved from downtown manhattan to the countryside of long island , new york .
... | ### Summary:
: fractals have been very successful in quantifying the visual complexity exhibited by many natural patterns , and have captured the imagination of scientists and artists alike .
our research has shown that the poured patterns of the american abstract painter jackson pollock are also fractal .
this d... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: cardiovascular disease is the leading cause of death in patients with chronic kidney disease ( ckd ) .
cardiovascular mortality in patients with e... | ### Summary:
: background and aimscardiovascular ( cv ) disease is the leading cause of morbidity and mortality in hemodialysis ( hd ) patients .
kidney disease is associated with increased oxidative stress ( os ) , a nontraditional cv risk factor .
few studies evaluate the effect of os markers on cv events ( cve... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: cp describes a group of permanent disorders of the development of movement and posture , causing activity limitation , that are attributed to nonpro... | ### Summary:
: aim and objective : cerebral palsy ( cp ) is the most common motor disability in childhood .
this study aimed to describe clinical spectrum , comorbidities , and risk factors associated with cp children.materials and methods : this hospital - based observational study was conducted in tertiary level ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the study population consisted of all consecutive patients undergoing ccta in our institution between 1 december 2003 and 29 february 2008 , for eva... | ### Summary:
: objectivediabetic patients have a high prevalence of coronary artery disease ( cad ) , but timely diagnosis of cad remains challenging .
we assessed the ability of coronary computed tomography angiography ( ccta ) to detect cad in diabetic patients and to predict subsequent cardiac events.research de... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the postinfectious irritable bowel syndrome is characterized by the sudden onset of symptoms mentioned in the diagnostic criteria for irritable bowe... | ### Summary:
: after acute infectious gastroenteritis , up to thirty percent of patients present prolonged gastrointestinal symptoms and a part of those affected patients can have the diagnostic criteria for postinfectious irritable bowel syndrome.treatment is symptom directed rather than curative and includes agents... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: all protocols and experiments were approved by the washington university animals studies committee ( protocol 20150285 ) and followed national insti... | ### Summary:
: background & aimsintestinal adaptation is a compensatory response to the massive loss of small intestine after surgical resection .
we investigated the role of intestinal epithelial cell specific mammalian target of rapamycin complex 1 ( i - mtorc1 ) in intestinal adaptation after massive small bowe... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: it is estimated that half a million cases occur worldwide annually , making primary liver cancer the fifth most common malignancy in men and the nin... | ### Summary:
: backgroundthe incidence of hepatocellular carcinoma ( hcc ) continues to increase in japan , but the clinical characteristics of japanese patients with hcc have not been well described .
the aim of this study was to determine the frequencies and utilities of elevated -fetoprotein ( afp ) and des - ga... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the ovaries are the most common sites affected , but endometriosis can also involve the gastrointestinal tract , urinary tract , chest , and soft ti... | ### Summary:
: chest pain is a rare sign of thoracal endometriosis associated with endometrioma of the tubo - ovarian endometrioma .
we report the case periodic episodes of chest pain concurrent with menstruation in a 35-year - old female , in which ovarian endometrioma was diagnosed and left - sided oophorectomy w... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: bfgfbasic fibroblast growth factorcafcancer - associated fibroblastnatnormal fibroblast basic fibroblast growth factor cancer - associated fibroblas... | ### Summary:
: abstractcancer - associated fibroblasts ( cafs ) are major participants in the crosstalk between tumor cells and their microenvironment .
cafs provide not only multiple soluble factors but also metabolic fuels to promote tumor growth , invasion , and metastasis .
we discuss recent developments deli... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: radicular back pain is an important public health issue that can result in long term disability and poor quality of life .
conservative therapy is... | ### Summary:
: background : spinal stenosis of the thoracic spine is less common than that of the cervical and lumbar regions . due to the close proximity to thoracic and abdominal organs , surgical operations can be difficult and carry a greater risk of complications . the most efficacious intervention for thoracic ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: in 2000 , the 24 member boards of the american board of medical specialties , including the american board of pathology , agreed to evolve their rec... | ### Summary:
: we examined how pathologists process their perceptions of how their interpretations on diagnoses for breast pathology cases agree with a reference standard . to accomplish this , we created an individualized self - directed continuing medical education program that showed pathologists interpreting brea... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: hek293 cells stably expressing human glp-1 receptor and a 3x - cre luciferase reporter were grown at 37c in 5% co2 in dulbecco 's modified eagle 's ... | ### Summary:
: objectivethe clinical effectiveness of parenterally - administered glucagon - like peptide-1 ( glp-1 ) mimetics to improve glucose control in patients suffering from type 2 diabetes strongly supports discovery pursuits aimed at identifying and developing orally active , small molecule glp-1 receptor ag... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: multiple sclerosis ( ms ) is an inflammatory disease characterized by damage to the myelin sheath surrounding neurons in the central nervous system ... | ### Summary:
: purposealthough smoking is known to cause various symptoms in multiple sclerosis ( ms ) patients , there have been no reports regarding the relationship between smoking and cognitive impairment in ms .
studying the effects of cigarette smoking in ms patients is imperative as there is a high prevalenc... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: glomerular disease , characterized by focal and segmental glomerulosclerosis histology ( fsgs ) , is a challenging disease to treat due to its frequ... | ### Summary:
: mutations in the inverted formin 2 gene ( inf2 ) have recently been identified as the most common cause of autosomal dominant focal and segmental glomerulosclerosis ( fsgs ) . in order to quantify the contribution of various genes contributing to fsgs , we sequenced inf2 where all mutations have previo... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: a simulation for each dipeptide ( in their zwitterionic form ) was set up using the gromacs molecular dynamics package .
a cubic box with 300 dipe... | ### Summary:
: several short peptide sequences are known to self - assemble into supramolecular nanostructures with interesting properties . in this study ,
coarse - grained molecular dynamics is employed to rapidly screen all 400 dipeptide combinations and predict their ability to aggregate as a potential precurso... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: alzheimer 's disease ( ad ) is a progressive brain disease affecting the elderly population , causing problems with memory , thought , and behavior ... | ### Summary:
: beta - secretase ( bace1 ) is the major enzyme participating in generation of toxic amyloid - beta ( a ) peptides , identified in amyloid plaques of alzheimer 's disease ( ad ) brains .
its downregulation results in decreasing secretion of a. thus , bace1 silencing by rnai represents possible strateg... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: phenylketonuria ( pku ; omim 261600 ) is defined as an autosomal recessive genetic inborn error of phenylalanine ( phe ) metabolism ( 1 ) .
insuff... | ### Summary:
: objective(s):phenylketonuria ( pku ) is a genetic inborn error of phenylalanine ( phe ) metabolism resulting from insufficiency in the hepatic enzyme , phenylalanine hydroxylase ( pah ) , which leads to elevated levels of phe in the blood .
the present study was carried out for mutation analysis of t... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: parkinson 's disease ( pd ) is one of the most common neuro - degenerative disorders characterized by tremor , bradykinesia , rigidity and postural ... | ### Summary:
: background : patients with psoriasis might be at a higher risk of developing parkinson 's disease ( pd ) as a result of the detrimental effect of chronic inflammation on the neuronal tissue . this meta - analysis aimed to investigate this risk by comprehensively reviewing all available data.methods:we ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: even though there have been continual advances in neonatal care and a decline in mortality of preterm infants in the past several decades , the inci... | ### Summary:
: objective : this study aimed to determine the impact of maternal cervical incompetence ( with or without mcdonald cerclage ) on mortality and morbidity of preterm infant with birth weight < 2000g.methods:581 neonates were eligible for this study , 79 with cervical incompetence and 502 without it ( cont... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: glaucoma is a progressive , vision - threatening disease characterized by functional and structural ocular abnormalities and is commonly associated ... | ### Summary:
: backgroundthe purpose of this study was to evaluate the safety and efficacy of a long - term , twice - daily brinzolamide 1%/timolol 0.5% fixed combination ophthalmic suspension ( brinz / tim - fc ) in japanese patients with open - angle glaucoma ( primary open - angle , normal - tension , exfoliation ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: leptin is a hormone that was initially found to be synthesized by white adipocytes and has a strong correlation with the amount of adipose tissue an... | ### Summary:
: obesity is an important risk factor for osteoarthritis ( oa ) in weight - bearing joints , but also in hand joints , pointing to an obesity - related metabolic factor that influences on the pathogenesis of oa .
leptin is an adipokine regulating energy balance , and it has recently been related also t... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: iranian traditional medicine ( itm ) is rich in intact information about plants that have been used to treat various diseases , especially skin diso... | ### Summary:
: herbal therapy was the common treatment prescribed by iranian physicians for wound healing .
zemad was the most ancient pharmaceutical dosage form used in iranian traditional medicine ( itm ) for skin diseases . in the present research , formulation of a
traditionally used poly herbal paste ( php ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: monoclonal immunoglobulin deposition disease , ( midd ) is a systemic disease characterized by non - fibrillar , congo red negative deposition of mo... | ### Summary:
: monoclonal immunoglobulin deposition disease ( midd ) is an uncommon disease with a peak incidence between the 5th and 6th decades of life .
it is characterized by non - fibrillar , congo red negative deposition of monoclonal immunoglobulins in various organs , including in the kidneys .
midd can b... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: several governmental and scientific bodies are dedicated to ensuring protection of the public from radiation .
the international commission on rad... | ### Summary:
: potassium iodide ( ki ) is recommended as an emergency treatment for exposure to radioiodines , most commonly associated with nuclear detonation or mishaps at nuclear power plants .
protecting the thyroid gland of infants and children remains a priority because of increased incidence of thyroid cance... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: current hiv prevention strategies ( condoms and abstinence ) force hiv - serodiscordant couples to choose between risking hiv transmission to a part... | ### Summary:
: background . understanding hiv - infected patient experiences and perceptions of reproductive counseling in the health care context is critical to inform design of effective pharmaco - behavioral interventions that minimize periconception hiv risk and support hiv - affected couples to realize their fer... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the objective signs and subjective symptoms of dry eye fluctuate greatly across patient populations , creating a significant challenge for the clini... | ### Summary:
: objective : the purpose of the current study was to evaluate the effects of two marketed ocular lubricants on the visual decay in dry eye patients using the inter - blink interval visual acuity decay ( ivad ) test.methods:this controlled , randomized , double - masked crossover study compared the effec... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the early and late mortality after acute myocardial infarction ( ami ) is declining , but cardiovascular disease ( cvd ) is still one of the leading... | ### Summary:
: background . matrix metalloproteinase-9 ( mmp-9 ) , regulated by tissue inhibitor of metalloproteinase-9 ( timp-1 ) and the extracellular matrix metalloproteinase inducer ( emmprin ) , contributes to plaque instability .
autologous stem cells from bone marrow ( mbmc ) treatment are suggested to reduc... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: tarsal plates removed from fresh cadaver 's upper and lower eyelids of a healthy caucasian female donor ( 36 years of age ) were obtained from mid -... | ### Summary:
: purposelittle is known about the signaling mechanisms controlling meibomian gland ( mg ) homeostasis and the pathogenic processes leading to mg atrophy and dysfunction in dry eye disease ( ded ) .
we investigated the role of fibroblast growth factor receptor 2 ( fgfr2 ) in the mg homeostasis of adult... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: assessment of functional capacity is important for identifying the physical implications of
stroke , since it is currently considered the main cau... | ### Summary:
: [ purpose ] the aim of this study was to investigate the associations between self - reported
and valid performance - based measures of functional capacity in individuals with chronic
stroke . [ subjects and methods ] self - reported measures of functional capacity of 31
individuals with chronic ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: dendritic cells ( dcs ) are professional antigen - presenting cells that possess the unique capacity to activate and prime naive cd4 and cd8 t cells... | ### Summary:
: dendritic cells ( dcs ) are central players of immune responses ; they become activated upon infection or inflammation and migrate to lymph nodes , where they can initiate an antigen - specific immune response by activating naive t cells .
two major types of naturally occurring dcs circulate in perip... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: unless otherwise noted , all reagents were purchased from sigma aldrich ( st . louis , mo , usa ) and used without further purification .
boc - g... | ### Summary:
: the need for post - synthetic modifications and reactive prosthetic groups has long been a limiting factor in the synthesis and study of peptidic and peptidomimetic imaging agents . in this regard ,
the application of biologically and chemically orthogonal reactions to the design and development of n... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: recently , the belgian government issued a bill regulating the organisation of and minimal requirements for specialist breast units ( kb , 2007 ) . ... | ### Summary:
: aim : criteria for future accreditation of breast cancer centres in belgium will be mainly based on the case load per surgeon or per centre .
we would like to argue that the prospective collection of relevant data and the analysis of treatment related outcome derived from these data is feasible and ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: spinocerebellar ataxias ( scas ) are autosomal - dominant neurodegenerative diseases that are clinically and genetically heterogeneous .
scas are ... | ### Summary:
: backgroundspinocerebellar ataxias ( scas ) are autosomal - dominant neurodegenerative diseases that are clinically and genetically heterogeneous .
scas are characterized by a range of neurological symptoms .
sca12 is an autosomal - dominant ( ad ) ataxia caused by a cag repeat expansion mutation in... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: traditionally , this has been via the abdominal or vaginal routes . in the present era , hysterectomies are undertaken using minimal access techniqu... | ### Summary:
: we compared the duration of surgery , blood loss , and complications between patients in whom both uterine arteries were ligated at the beginning of total laparoscopic hysterectomy ( tlh ) and patients in whom ligation was done after cornual pedicle . using a prospective study in a gynecologic laparosc... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: when multiple hypotheses are tested in a single experiment , the risk of type i error is increased and with it the risk of promulgating spurious si... | ### Summary:
: increased type i error resulting from multiple statistical comparisons remains a common problem in the scientific literature .
this may result in the reporting and promulgation of spurious findings .
one approach to this problem is to correct groups of p - values for family - wide significance us... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the most ideal outcomes for tumor targeted therapy are improved patient survival and minimal adverse effects on normal tissues .
drugs that can sp... | ### Summary:
: epithelial cell adhesion molecule ( epcam ) is a type i transmembrane glycoprotein overexpressed in human epithelioma but with relatively low expression in normal epithelial tissues . to exploit this differential expression pattern for targeted cancer therapy ,
an epcam - targeted immunotoxin was dev... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: staphylococcus aureus is an important food - borne pathogen involved in a variety of invasive diseases ( 1 ) .
it produces many toxins as well as ... | ### Summary:
: background and objectivesstaphylococcal food poisoning is a gastrointestinal disease , which is caused by consumption of contaminated food with enterotoxins produced by staphylococcus aureus ( ses ) .
milk and its products are known sources of food borne diseases .
this study was carried out to eva... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: bisphosphonate - related osteonecrosis of the jaw ( bronj ) is currently defined as an area of exposed bone in the maxillofacial region that has per... | ### Summary:
: purpose . to report the efficacy of conservative surgical treatment for stage i bisphosphonate - related osteonecrosis of the jaw ( bronj ) .
materials and methods .
this study reports the clinical outcomes of 63 patients treated for bronj stage i ( according to ruggiero 's staging system ) at the ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: preanalytical problems are the major source of laboratory errors , accounting for 6070% of total errors encountered within the total testing process... | ### Summary:
: tacrolimus and cyclosporine a are immunosuppressant drugs with narrow therapeutic windows . the aim of this study was to investigate the stability of tacrolimus and cyclosporin a levels in whole blood samples under different storage conditions .
whole blood samples were obtained from 15 patients rece... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: a group of 14 university hospitals participated in this study and 72 patients were recruited between 1992 and 2006 . individuals with confirmed hnf1... | ### Summary:
: objectivematurity onset diabetes of the young type 3 ( mody3 ) is a consequence of heterozygous germline mutation in hnf1a .
a subtype of hepatocellular adenoma ( hca ) is also caused by biallelic somatic hnf1a mutations ( h - hca ) , and rare hca may be related to mody3 . to better understand a rela... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: along with the increase in the prevalence of type 1 diabetes mellitus ( t1 dm ) the number of patients with chronic vascular complications will rise... | ### Summary:
: the aim of this study was to evaluate the relationship between serum transforming growth factor 1 ( tgf-1 ) concentrations and the duration of type 1 diabetes mellitus ( t1 dm ) in children and adolescents .
one hundred and sixteen patients with t1 dm and 19 healthy controls were examined .
serum t... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: mesenchymal stromal cells , also referred to as mesenchymal stem cells ( mscs ) , were first discovered in 1974 .
mscs are a heterogeneous group o... | ### Summary:
: abstractover the past 2 decades , therapies based on mesenchymal stem cells ( msc ) have been tested to treat several types of diseases in clinical studies , due to their potential for tissue repair and regeneration .
currently , msc - based therapy is considered a biologically safe procedure , with ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the prevalence of type 2 diabetes continues to rise and currently affects over 25 million americans and is estimated to reach 439 million adults wor... | ### Summary:
: to examine whether behavioral risk factors associated with diabetes ( diet , bmi , waist circumference , physical activity , and sleep duration ) are also related to both prediabetes and insulin resistance ( ir ) , we used data from boston area community health ( bach ) survey ( 20102012 , n = 3155 ) .... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: in a quasi - experimental study carried out in 2009 - 2010 academic year and 63 medical students from isfahan university of medical sciences studyin... | ### Summary:
: background : it has been demonstrated that educational programs that focus on study skills could improve learning strategies and academic success of university students . due to the important role of such supportive programs aimed at the fresh students ,
this survey was carried out to investigate the... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: as medical house officers who trained together in internal medicine in the 1980s , we ( jnk , sal ) believed we knew who provided the highest - qual... | ### Summary:
: for much of the twentieth century , quality of care was defined specifically in terms of physician characteristics and behaviors .
high - quality physicians were well trained , knowledgeable , skillful , and compassionate .
more recently , quality of care has been defined in terms of systems of car... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: according to the international headache society ( ihs ) , classical trigeminal neuralgia ( tn ) is defined as a unilateral disorder characterized b... | ### Summary:
: it is unclear whether hypertension ( htn ) is a predisposing factor for the development of trigeminal neuralgia ( tn ) .
the purpose of this study was to determine the prevalence of htn in tn patients and controls at the usc orofacial pain and oral medicine center .
a retrospective chart review was... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: acute lymphoblastic leukemia ( all ) is a hematological malignant disorder caused by excessive production of leukocytes and is the most common malig... | ### Summary:
: great improvements have been made in acute lymphoblastic leukemia ( all ) treatment in the past decades , especially due to the use of l - asparaginase ( l - asp ) . despite the significant success rate ,
several side effects mainly caused by toxicity , asparaginase silent inactivation , and cellular... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: continuous ambulatory peritoneal dialysis ( capd ) is an important treatment option for patients with end - stage renal disease .
although the rat... | ### Summary:
: rothia muciliaginosa ( r. mucilaginosa ) is a facultative , gram - positive coccus that is considered to be part of the normal flora of the mouth and respiratory tract .
there are sporadic reports of the organism causing endocarditis in patients with heart valve abnormalities , as well as meningitis ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the greatest association of helicobacter pylori ( h. pylori ) infection is with peptic ulcer disease .
recently , the association between h. pylor... | ### Summary:
: a triple therapy based on a proton pump inhibitor ( ppi ) , amoxicillin ( ampc ) , and clarithromycin ( cam ) is recommended as a first - line therapy for helicobacter pylori ( h. pylori ) eradication and is widely used in japan .
however , a decline in eradication rate associated with an increase in... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: patients commonly present with acute cholinergic crisis , intermediate syndrome , or delayed polyneuropathy . they may also present with pancreatiti... | ### Summary:
: renal complications due to organophosphate poisoning are very rare .
we are presenting a unique case of transient distal renal tubular acidosis due to organophosphate poisoning , which to the best of our knowledge is the first of its kind .
an elderly female after deliberate self - harm with ingest... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: clefts of the anterior and posterior arch of the atlas are rare , but well - documented congenital anomalies [ 1 , 2 ] .
several reports attribute... | ### Summary:
: we report on the case of a 15-year - old adolescent who presented with a transient paraplegia and hyposensibility of the upper extremities after sustaining a minor hyperflexion trauma to the cervical spine .
neuroimaging studies revealed atlantoaxial dislocation and ventral compression of the rostral... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the population of republic of korea is aging at an unprecedented fast rate . and per capita medical utilization due to geriatric illness
has incre... | ### Summary:
: we are rapidly becoming an aging society , with the ongoing increase in challenges of the elderly .
the age - related cognitive decline in accordance with aging society is of major importance in public health .
recent studies have proved the impacts of sex - steroid hormone on the brain ; compliant... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the wnt signaling pathway is known to play a key role in regulating cellular differentiation , proliferation , survival , and apoptosis [ 13 ] .
w... | ### Summary:
: the wnt signaling pathway has been associated with many essential cell processes .
this study aims to examine the effects of wnt signaling on proliferation of cultured hek293 t cells .
cells were incubated with wnt3a , and the activation of the wnt pathway was followed by analysis of the level of t... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: nutrition security ensures optimal actualization of human resources and overall progress and development of a society and nation .
malnutrition ( ... | ### Summary:
: iodine deficiency disorders ( idd ) constitute the single largest cause of preventable brain damage worldwide .
majority of consequences of idd are invisible and irreversible but at the same time these are preventable . in india ,
the entire population is prone to idd due to deficiency of iodine in... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the isolation of pure , intact , and high - quality dna is very crucial for any molecular studies . however , dna isolation from plants is usually c... | ### Summary:
: mangroves and salt marsh species are known to synthesize a wide spectrum of polysaccharides and polyphenols including flavonoids and other secondary metabolites which interfere with the extraction of pure genomic dna .
although a plethora of plant dna isolation protocols exist , extracting dna from m... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: the recent medical developments , including the increased use of chemotherapy drugs , white blood cell stimulants , and broad spectrum antibiotics ,... | ### Summary:
: background . pediatric patients with neoplastic diseases are more likely to develop nosocomial infections ( nis ) .
nis may prolong their hospital stay , and increase morbidity and mortality .
objectives .
the objectives of this study were to determine : ( 1 ) the incidence of nis , ( 2 ) sites o... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: force measurements on a scaled hair - bundle model respected the physiological character of the liquid flow .
the finite - element method provided... | ### Summary:
: the detection of sound begins when energy derived from an acoustic stimulus deflects the hair bundles atop hair cells1 .
as hair bundles move , the viscous friction between stereocilia and the surrounding liquid poses a fundamental physical challenge to the earfs high sensitivity and sharp frequency ... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: thromboembolic stroke is a known complication of non - valvular atrial fibrillation ( af ) .
therefore , the need to prevent such occurrence is of... | ### Summary:
: backgroundthe r2chads2 is a new prediction rule for stroke risk in atrial fibrillation ( af ) patients wherein r stands for renal risk .
however , it was created from a cohort that excluded patients with advanced renal failure ( defined as glomerular filtration rate of < 30 ml / min ) .
our study e... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: in europe , many countries will be confronted with aging populations in the coming decades .
for example , it is estimated that in 2020 , 28% of t... | ### Summary:
: this research takes place in the s(ma)2d project which proposes software architecture to monitor elderly people in their own homes .
we want to build patterns dynamically from data about activity , movements , and physiological information of the monitored people . to achieve that
, we propose a mu... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: according to the definition of world health organization ( who ) , quality of life ( qol ) is the individual 's perception of his / her position in... | ### Summary:
: background : although studies have demonstrated significant negative relationships between quality of life ( qol ) , fatigue , and the most common psychological symptoms ( depression , anxiety , stress ) , the main ambiguity of previous studies on qol is in the relative importance of these predictors .... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: in recent years , we have witnessed a profound revolution in the way we approach and treat renal cell carcinoma ( rcc ) . in a relatively short time... | ### Summary:
: in the past ten years we have made exceptional progresses in the understanding of rcc biology , particularly by recognizing the crucial pathogenetic role of activation of the hif / vegf and mtor pathways .
this has resulted in the successful clinical development of anti - angiogenic and mtor - target... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: our initial sample consisted of 87 hcv+ participants who were recruited from several hepatology clinics and infectious disease clinics located throu... | ### Summary:
: objective : this study examined neurologic abnormalities ( as measured by proton magnetic resonance spectroscopy imaging and diffusion tensor imaging ) , neurocognitive performance , and fatigue among a sample of adults with hepatitis c virus ( hcv ) .
we hypothesized that hcv+ individuals would demo... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: castleman 's disease ( cd ) or giant lymph node hyperplasia is a rare disorder first explained by castleman et al . , in 1954
. it can be unicentr... | ### Summary:
: castleman 's disease ( cd ) or giant lymph node hyperplasia is a rare disorder that can be unicentric or multicentric .
multicentric castleman 's disease ( mcd ) is manifested by generalized lymphadenopathy , hepatosplenomegaly , polyclonal hypergammaglobulinemia , hematological abnormality , and con... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: hepatocellular carcinoma ( hcc ) in adult men is the 5th most frequently diagnosed cancer worldwide , and is the 2nd leading cause of cancer - relat... | ### Summary:
: abstractstatins are associated with a reduced risk of hepatocellular carcinoma ( hcc ) and have the potential to be an adjuvant agent for hcc . in this study , we examined whether statin use is associated with additional benefits among patients who received curative treatments ( cts ) such as surgery ,... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: patients with mild copd often use inhaled corticosteroids without a need for them . a clinical audit including spirometry was useful for identifying... | ### Summary:
: background : inhaled glucocorticosteroids ( ics ) are first - line anti - inflammatory treatment in asthma , but not in chronic obstructive pulmonary disease ( copd ) . to restrict ics use in copd to cases of severe disease ,
new terms for reimbursement of drug costs were introduced in norway in 2006... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: steroid - responsive encephalopathy associated with subacute thyroiditis has , to our knowledge , not been reported previously .
a 49-year - old w... | ### Summary:
: backgroundsteroid - responsive encephalopathy associated with subacute thyroiditis has , to our knowledge , not been reported previously.case reporta 49-year - old woman was found collapsed and brought to our institution with decreased mentality , dysarthria , and gait disturbance .
brain magnetic re... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: evaluation of athletic hip pain routinely includes radiographs and magnetic resonance imaging ( mri ) .
computed tomography ( ct ) is applied at s... | ### Summary:
: femoro - acetabular impingement is a common cause of hip pain in young athletes .
evaluation typically includes radiographs and magnetic resonance imaging .
it is important to appreciate uncommon diagnoses and the role of complimentary imaging .
this clinical vignette emphasizes the need complete... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: despite its world - wide omnipresence in soil , a. fumigatus had been considered asexual until studies of an aspergillus - like anamorph isolated fr... | ### Summary:
: we describe the first reported case of acute respiratory distress syndrome ( ards ) attributed to neosartorya udagawae infection .
this mold grew rapidly in cultures of multiple respiratory specimens from a previously healthy 43-year - old woman .
neosartorya spp .
are a recently recognized cause... |
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text:
: nowadays , laboratory services play a major role in optimizing patient care . in some circumstances , increased laboratory use is allowed such as : ... | ### Summary:
: background : routine repeat testing of critical laboratory values is very common these days to increase their
accuracy and to avoid reporting false or infeasible results .
we figure that repeat testing of critical laboratory
values has any benefits or not .
methods : we examined 2233 repeated c... |
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