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<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : haemophilus spp . generally colonize the upper respiratory tract and can cause infections such as bronchitis , sinusitis , epiglottitis , pneumonia ...
### Summary: : haemophilus species are known to colonize the upper respiratory tract and can cause infections . however haemophilus influenzae has been rarely described as a cause of genitourinary tract infection . we report a 44-year - old nonimmunocompromised japanese man with bacteremic pyelonephritis caused b...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the long - term survival of patients with hematological malignancies has improved dramatically over the past decades . nowadays , about 40% of pat...
### Summary: : the spectacular improvement in long - term prognosis of patients with hematological malignancies since the 1980s , coupled with the subsequent improvement over the past decade in short- and mid - term survival in cases of critical illness , resulted in an increasing referral of such patients to the icu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic hepatitis c ( chc ) is a major health care burden and a leading cause of end - stage liver disease and hepatocellular carcinoma ( hcc ) worl...
### Summary: : background : single - nucleotide polymorphisms ( snp ) in the inosine triphosphate pyrophosphatase ( itpa ) gene correlate with ribavirin ( rbv)-induced anemia in patients with chronic hepatitis c ( chc ) receiving combination therapy . managing anemia is an early priority in the treatment process.ob...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : endometrial carcinoma is the most common cancer of the female genital tract in the western world . endometrial carcinomas are generally thought to...
### Summary: : background . the aim was to evaluate predictive and prognostic factors in a large consecutive series of endometrial carcinomas and to discuss pre- and postoperative risk groups based on these factors . material and methods . in a consecutive series of 4,543 endometrial carcinomas predictive and progn...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : fistula - in - ano is an abnormal hollow tract lined by unhealthy granulation tissue connecting a primary opening in the anal canal to a secondary o...
### Summary: : background : fistula - in - ano when complicated by fournier 's gangrene is an unusual finding and always carries high morbidity . this study details our experience in managing 10 cases.methods of study : case files of all patients managed in university of maiduguri teaching hospital and federal medi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : congenital coarctation of the aorta is a narrowing of the descending aorta which typically is located at the ligamentum arteriosum just distal to th...
### Summary: : the present case shows that a normal brachial blood pressure ( bp ) does not exclude severe coarctation and should be considered in normotensive patients presenting with a systolic murmur and/or unexplained severe left ventricular hypertrophy . congenital coarctation of the aorta is a narrowing of th...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : multistep skin carcinogenesis assays were performed with mice with keratinocyte - specific deletion of the cnb1 gene ( cnb1xk5-crepr1)3 in parallel ...
### Summary: : calcineurin inhibitors such as cyclosporin a ( csa ) are the mainstay of immunosuppressive treatment for organ transplant recipients . squamous cell carcinoma ( scc ) of the skin is a major complication of treatment with these drugs , with a 65100 fold higher risk than in the normal population1 . b...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : micrornas ( mirnas ) are single stranded non - coding rna molecules of 22 nucleotides ( nt ) that regulate gene expression via post - transcriptiona...
### Summary: : micrornas ( mirnas ) are small non - coding rnas ( 22 nucleotides ) regulating gene expression at the post - transcriptional level . by directing the rna - induced silencing complex ( risc ) to bind specific target mrnas , mirna can repress target genes and affect various biological phenotypes . fu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : prostate cancer , one of the most commonly diagnosed male malignancies in western countries , is now the leading cause of cancer - related death in ...
### Summary: : the sperm protein associated with the nucleus in the x chromosome ( spanx ) gene family encodes for proteins that are not only expressed in germ cells , but also in a number of tumors . in addition , spanx genes map in an interval of the x chromosome ( namely , xq27 ) , which has been found to be assoc...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : gli2 mice , in which the bovine k5 promoter drives the constitutive expression of mouse gli26 , develop bcc and bfh6,7 , which are both linked to de...
### Summary: : basaloid skin tumors , including basal cell carcinoma ( bcc ) and basaloid follicular hamartoma ( bfh ) , are associated with aberrant hedgehog ( hh ) signaling1 and , in the case of bcc , an expanding set of genetic variants including keratin 5 ( k5)2 , an intermediate filament - forming protein . w...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : most vertebrates are unable to grow and reach their normal adult form without the thyroid hormone [ 1 , 2 ] . however , various subsequent studies...
### Summary: : altered thyroid function during early stages of development is known to affect adversely testicular growth , physiology , and antioxidant defence status at adulthood . the objective of the present study is to investigate the modulation of antioxidant defence status in neonatal persistent hypothyroid ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : ewing 's sarcoma family of tumors are a group of small round - cell neoplasms , which include ewing 's sarcoma ( ews ) , primitive neuroectodermal t...
### Summary: : ewing 's sarcoma / peripheral primitive neuroectodermal tumors occur most often in bone and soft tissues of children and young adults . the intracranial manifestation of the disease is rare , and when present , this is often misdiagnosed with other varieties of primary brain tumors . we report such...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : nitric oxide ( no ) is known to have several important vasculo - protective effects ( el - mas et al 1997 ; grdal et al 2005 ) . reduced production ...
### Summary: : we recruited 560 unrelated patients with ischemic stroke and 153 unrelated controls to undertake a genetic analysis for association between the nos3 gene and ischemic stroke . all the subjects were chinese of han descent . because the nos3 gene spans about 21 kb of dna and contains 26 exons , we sele...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : it is located at the interface of these two vastly different environments , and thus is charged with making the final decision about what , from an ...
### Summary: : taste is the final arbiter of which chemicals from the environment will be admitted to the body . the action of swallowing a substance leads to a physiological consequence of which the taste system should be informed . accordingly , taste neurons in the central nervous system are closely allied wit...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 36-year - old man visited the emergency department of inje university haeundae paik hospital with severe pain in both lower limbs for 1 day . a ph...
### Summary: : kimura disease ( kd ) is an immune - mediated chronic inflammatory disease of unknown etiology . kd has many complications associated with hypereosinophilia , including various forms of allergic reactions and eosinophilic lung disease . additionally , hypereosinophilia is associated with hypercoagu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : businesses offering goods and services to consumers often request feedback from former customers to assess strengths and weaknesses and to leverage ...
### Summary: : objective . the primary objective of this investigation is to determine which individual and aggregate factors of residential addiction treatment centers are most significant influencers of alumni satisfaction . design . survey targeted alumni of residential addiction treatment facilities . alu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the majority of japanese patients with type 2 diabetes mellitus are not obese , as reported by kosaka and ogata more than 50 years ago . eastern a...
### Summary: : aims . we analyzed the prevalence of nephropathy according to past body weight status in japanese subjects with type 2 diabetes because the influence of past obesity on diabetic complications is not certain . methods . we examined the prevalence of nephropathy in 2927 subjects with type 2 diabetes ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : monoamine oxidases ( mao ) are mitochondrial enzymes responsible for the metabolic breakdown of monoamines ( serotonin , norepinephrine , and dopami...
### Summary: : linezolid is a synthetic antimicrobial agent of the oxazolidinone class with weak , nonspecific inhibitor of monoamine oxidase enzymes . concomitant therapy with an adrenergic or serotonergic agent or consuming tyramine ( > 100 mg / day ) may induce serotonin syndrome ( ss ) . we present a case rep...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : aerobic ammonia oxidation , the first and rate - limiting step in nitrification , is the only biological process converting reduced to oxidized inor...
### Summary: : thaumarchaeota range among the most abundant archaea on earth . initially classified as mesophilic crenarchaeota , comparative genomics has recently revealed that they form a separate and deep - branching phylum within the archaea . this novel phylum comprises in 16s rrna gene trees not only all ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic obstructive pulmonary disease ( copd ) is a chronic respiratory disease characterized by a progressive decline in lung function and accompan...
### Summary: : purposein the absence of head - to - head clinical trials comparing the once - daily , long - acting beta2-agonists olodaterol and indacaterol for the treatment of chronic obstructive pulmonary disease ( copd ) , an indirect treatment comparison by systematic review and synthesis of the available clini...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion , insulin action , or both ( 1 ...
### Summary: : introduction : diabetes is a group of metabolic diseases characterized by hyperglycemia , and represents a disease of the modern age , disease of the 21st century . prevention of this disease is listed as imperative . aim of this article was to evaluate questionnaires on the assessment of risk fact...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : acute right heart syndrome ( arhs ) may be defined as sudden deterioration in the right ventricular ( rv ) function and failure of the rv of the hea...
### Summary: : acute right heart syndrome is a sudden deterioration in right ventricular performance , resulting in right ventricular failure and confers significant in - hospital morbidity and mortality . in critically ill patients , the syndrome is often undiagnosed and untreated , as these patients do not usually ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in rare conditions , bacteria from carbuncles can spread into the bloodstream and migrate to other areas of the body , causing serious complications...
### Summary: : although carbuncles are commonly seen and may heal on their own or respond well to treatment , in rare conditions , bacteria from carbuncles can spread into the bloodstream and migrate to other areas of the body . herein , we report on an elderly female who suffered from forehead carbuncle with intra...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hydroxyl radicals , generated by cellular oxidative stress and inflammation , damage nucleobases or deoxyribose sugars , or both in dna . at 2-d...
### Summary: : diastereomeric 8,5-cyclopurine 2-deoxynucleosides , containing a covalent bond between the deoxyribose and the purine base , are induced in dna by ionizing radiation . they are suspected to play a role in the etiology of neurodegeneration in xeroderma pigmentosum patients . if not repaired ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the collective arrangement of the teeth in function is quite important and has been subjected to a great deal of analysis and discussion over the ye...
### Summary: : background and aims this study observed occlusal contacts and their area on the teeth during lateral mandibular movements . the percentage of each occlusal pattern was determined . materials and methods fifty subjects ( male : 27 , female : 23 ) , aged 20 - 29 years , were included in the study...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : zinc deficiency is an important cause of morbidity due to infectious diseases and growth - faltering among young children . increased demand of zinc...
### Summary: : community - based data relating to factors influencing zinc deficiency among preschool children in india are inadequate . data of a large , double - blinded , randomized , controlled zinc - supplementation trial were used for assessing the descriptive epidemiology of zinc deficiency among children aged...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : intradural disc herniation ( idh ) is a rare disease and its incidence is reported as 0.26 - 0.30% of all disc herniations16 ) . idhs primarily oc...
### Summary: : intradural lumbar disc herniation is a rare disease . according to the reports of intradural lumbar disc herniations , most cases have developed as a chronic degenerative disc diseases . traumatic intradural lumbar disc herniations are even rarer . a 52-year - old man visited our emergency center...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : initially , they were considered as metastasis from an occult primary tumor in gonads , but now it is known that they arise either as a consequence ...
### Summary: : choricarcinoma is a beta human chorionic gonadotrophin secreting neoplasm pertinent to uterus and pregnancy mostly . it occurs primarily in gonads but rarely in extragonadal sites . primary hepatic choriocarcinoma is an extremely rare tumor . most of the reported cases are seen in infants represe...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : human ifn-2 ( il-28a ) is a relatively new cytokine , in which the genomic structure resembles that of the il-10 family , but the protein structure ...
### Summary: : this study investigated the expression levels of interferon- ( ifn- ) 2 in peripheral blood and tissues . the results showed that the levels of ifn-2 were elevated by 17.9% and 14.2% in the plasma of allergic rhinitis ( ar ) and combined rhinitis with asthma ( ar + as ) , which was positively correla...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : sodium nitrate ( nano2 ) is one of important environmental toxicants and poses important health risks . most countries use nano2 as food additive ...
### Summary: : sodium nitrate ( nano2 ) widely used as food additive for coloring and preserving meat has been reported to induce oxidative stress and cause histopathologic changes , nitrosative tissue damage , and lipid peroxidation in liver and kidney . therefore , the present study compared the curative effect o...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : placental polyp is a somewhat pedunculated remnant of chorionic tissue retained in the uterine cavity for an indefinite time . it may result in ab...
### Summary: : placental polyp is retained placental tissue within the endometrial cavity , which forms a nidus for inflammation and bleeding . there are very few reported cases of the clinical placental polyp . here , we report a case of 34-year - old g4l3ab1 woman with the chief complaint of intermittent vagina...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : halogen bonding has emerged in recent years as an effective alternative to hydrogen bonding in directing the formation of self - assembling ar...
### Summary: : halogen bonding , due to its directionality and tunable strength , is being increasingly utilized in self - assembling materials and crystal engineering . using density functional theory ( dft ) and molecular mechanics ( opls / cm1ax ) calculations , multiply halogen bonded complexes of bromi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in recent years , the development of an integrated nanotherapeutic system which can allow for an online imaging and deliver targeted therapy has bee...
### Summary: : in this study , we synthesized a multifunctional nanoparticulate system with specific targeting , imaging , and drug delivering functionalities by following a three - step protocol that operates at room temperature and solely in aqueous media . the synthesis involves the encapsulation of luminescent ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : benign prostatic hyperplasia ( bph ) is found in over half of 60-year - old men and in almost all 80-year - old men who develop bladder outlet obstr...
### Summary: : purposethe aim of this research was to assess the value of the transitional zone index ( tzi ) and intravesical prostatic protrusion ( ipp ) from transrectal ultrasonography in evaluating the severity and progression of disease by analyzing the relationship between the 2 parameters and symptoms , clini...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : apert syndrome ( acrocephalosyndactylia ) is a developmental malformation characterized by craniosynostosis , a cone - shaped calvarium ( acrocephal...
### Summary: : the purpose of this report is to present apert syndrome patient by highlighting craniofacial characteristics and orthodontic approach to treatment.the patient , a 16-day - old female and the second child of healthy parents , was admitted to our department with primary complaint of cleft palate . she ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : electrostatic potentials and free energies were calculated with a modified version of the delphi program , adapted to solve the nonlinear pois...
### Summary: : the heterotrimeric g protein transducin is a key component of the vertebrate phototransduction cascade . transducin is peripherally attached to membranes of the rod outer segment , where it interacts with other proteins at the membrane - cytosol interface . however , upon sustained activatio...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : , it accounts for the largest number of deaths from malignant neoplasms in women and the third largest number in men . however , since the recurre...
### Summary: : the patient was a 68-year - old man who was admitted to our hospital with a liver tumor . abdominal ultrasonography and computed tomography revealed a liver tumor 30 mm in diameter . on colonoscopy , a pedunculated tumor with a central depression ( 20 mm in diameter ) was observed in the ascending co...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the cases were collected from our melanoma database , and 30 patients who were treated from january 2001 to december 2010 were retrospectively revie...
### Summary: : backgrounda retrospective study was conducted to review the overall survival and treatment outcomes of high grade melanoma in the extremity to explore the clinical features of malignant melanoma of the hand and foot , and the therapeutic efficacies and survival rate after amputation.methodsthe clinical...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : granulocyte macrophage colony - stimulating factor ( gm - csf ) is a hematopoietic growth factor which was originally recognized as a stimulator for...
### Summary: : granulocyte macrophage - colony stimulating factor ( gm - csf ) is a hematopoietic growth factor , which stimulates the proliferation of granulocytes and macrophages from bone marrow precursor cells . in autoimmune and inflammatory diseases , th17 cells have been considered as strong inducers of tiss...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hypertrophic cardiomyopathy ( hcm ) is the most common cause of sudden death in young patients . whereas especially patients with a nonobstructive...
### Summary: : abstractwe report the case of a 17yearold female patient with known hypertrophic cardiomyopathy and a wolffparkinsonwhite syndrome . she came to our department for further evaluation of a new diagnosed dilated cardiomyopathy characterized by an enlargement of the left ventricle and a fall in ejection...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : bacteriocins are toxins produced by the bacteria to inhibit the growth of similar or closely related bacterial strain(s ) during stress conditions ....
### Summary: : xenorhabdus nematophila , a gram - negative bacterium belonging to the family enterobacteriaceae is a natural symbiont of a soil nematode from the family steinernematidae . in this study cloning , expression , and purification of broad range iron regulated multidomain bacteriocin called xenocin from ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : comet lysis buffer ( 2.5 m sodium chloride , 100 mm edta ( ph 8.0 ) , 1% sarkosyl , 10 mm tris hcl ( ph 8.0 ) , 10% dmso , 10% triton x-100 ) . com...
### Summary: : backgroundhydrogen peroxide ( h2o2 ) is a common reactive oxygen intermediate generated by various forms of oxidative stress.aimthe aim of this study was to investigate the dna damage capacity of h2o2 in hepg2 cells.methodscells were treated with h2o2 at concentrations of 25 m or 50 m for 5 min , 30 mi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : telemedicine utilization is rising due to the increased availability and decreased cost of communication technology , in parallel with growing recog...
### Summary: : telemedicine is an increasingly recognized option for cost - effective management of chronic conditions . we surveyed sleep clinic patients about their experiences and preferences regarding different forms of telemedicine . adult sleep clinic patients seen between 2009 and 2011 received a brief sur...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chromosome 22q13.3 deletion syndrome is a well - recognized cause of global developmental delay ( gdd ) [ 1 , 2 ] while duplication of the same chro...
### Summary: : chromosome 22q13.3 deletion syndrome is a well - recognized cause of global developmental delay , while duplication of the same chromosome is a rare occurrence . the presence of both abnormalities in the same family has never been reported , to our knowledge . we report a rare occurrence of 22q13.3...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in this study , we retrospectively selected 75 cases of formalin - fixed , paraffin - embedded hair - bearing adult skin samples between 2002 and 20...
### Summary: : backgroundcd99 is a cell surface transmembrane glycoprotein expressed in various tissues . cd99 is differentially expressed between subpopulations of each tissue and is highly expressed in certain hematopoietic and precursor cells . however , there has been no comprehensive study of cd99 expression...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : glaucoma remains the third or fourth most common cause of blindness in different regions around the globe . since this is a treatable disease , ea...
### Summary: : purpose . to compare two different spectral - domain optical coherence tomography ( oct ) systems in regard to full macular thickness ( mt ) and ganglion cell layer - inner plexiform layer ( gcipl ) measures and in regard to structure - function correlation when compared to standard automated perimetry...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in order to introduce a new plant variety to the markets commercially , it is necessary to register a newly bred variety , which relies upon the res...
### Summary: : identification and registration of new rice varieties are very important to be free from environmental effects and using molecular markers that are more reliable . the objectives of this study were , first , the identification and distinction of 40 rice varieties consisting of local varieties of iran...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : sequence - defined biopolymers , such as proteins and nucleic acids , incorporate backbone and side - chain constituents that endow these macr...
### Summary: : peptoids are a family of synthetic oligomers composed of n - substituted glycine units . along with other foldamer systems , peptoid oligomer sequences can be predictably designed to form a variety of stable secondary structures . it is not yet evident if foldamer design can be extended...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : malaria remains a serious global health problem , killing more than one million people per year . the number of malaria cases has fallen by more t...
### Summary: : globalization and urbanization with their inherent developmental activities and ecological transformations impact on malaria epidemiology . entomological factors involved in malaria transmission in periurban lusaka were assessed prior to vector control reintroduction . data was collected through st...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hydrocephalus refers to the accumulation of excessive cerebrospinal fluid ( csf ) within the brain or cranial vault . medical treatment of hydroce...
### Summary: : case summary ventriculoperitoneal shunt placement is the most commonly utilised surgical treatment for hydrocephalus in human and veterinary patients . migration of the peritoneal catheter is an uncommon but well - documented complication in people , usually occurring within the first 3 months postop...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : between 25% and 30% of non - small cell lung cancer ( nsclc ) patients will develop metastatic disease in the brain ( brain metastases from non - sm...
### Summary: : in the systemic treatment of brain metastases from non - small cell lung cancer ( bmf - nsclc ) chemo- and targeted therapy are used . response rates after platinum - based chemotherapy , range from 23% to 45% . development of epidermal growth factor receptor tyrosine kinase inhibitors ( egfr - tki...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : many organs can be herniated into the scrotum such as small intestine , appendix , colon , and ovaries . ureteral herniation is extremely rare , u...
### Summary: : an inguinoscrotal hernia is a common disorder that usually contains intraperitoneal organs ( small intestine , colon , appendix , ovaries ) . extraperitoneal ureteral herniation into an inguinoscrotal hernia is a rare condition and often associated with congenital abnormalities or postoperative anato...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: :
### Summary: : in the closed structure of the p2x cation channel , three -helical transmembrane domains cross the membrane obliquely : in rat p2x2 receptors , these intersect at thr339 . replacing thr339 by lysine in one , two or three subunits progressively increased chloride permeability and reduced unitary conduct...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the incidence of non - hodgkin lymphoma ( nhl ) is 100200-fold higher in hiv - infected individuals than in the general population . nhl is an aid...
### Summary: : primary mediastinal large b cell lymphoma ( pmlbcl ) is a subtype of diffuse large b cell lymphoma arising in the mediastinum with distinctive clinical and morphological features . though diffuse large b cell lymphoma is one of the most common non - hodgkin lymphoma associated with aids , there are n...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cardiovascular disease ( cvd ) is the main cause of death in maintenance hemodialysis ( mhd ) patients . both aortic artery calcification ( aac ) ...
### Summary: : background : this study was to investigate the relationship among aortic artery calcification ( aac ) , cardiac valve calcification ( cvc ) , and mortality in maintenance hemodialysis ( mhd ) patients.methods:all mhd patients in shanghai ruijin hospital in july 2011 were included . to follow up for 42 ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in an era of finite resources and ever - increasing medical possibilities , every health care system faces challenges in determining which new healt...
### Summary: : purposeintroducing new health technologies , including medical devices , into a local setting in a safe , effective , and transparent manner is a complex process , involving many disciplines and players within an organization . decision making should be systematic , consistent , and transparent . i...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in anterior cruciate ligament ( acl ) reconstruction , the use of bone patellar tendon bone graft ( bptb ) has been decreasing due to increased ante...
### Summary: : purposethis study evaluated mid - term results of anterior cruciate ligament ( acl ) reconstruction using the pinn - acl crosspin system that allowed for short graft fixation.materials and methodsforty - three patients underwent single - bundle acl reconstruction with a 4-strand semitendinosus tendon g...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : autosomal - recessive renal tubular dysgenesis ( ar - rtd ) is a rare inherited disorder caused by mutations in the genes encoding any of the compon...
### Summary: : autosomal - recessive renal tubular dysgenesis ( ar - rtd ) is a rare disorder caused by a genetic defect in the renin angiotensin system . although ar - rtd has typically been known as a lethal disease due to refractory hypotension and renal failure immediately after birth , few cases have reporte...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : patients with ibd should be periodically examined regarding their dermatologic conditions . in a previous report from iran , the prevalence of der...
### Summary: : some dermatologic manifestations are common in ulcerative colitis ( uc ) . herein , we present a 36-year - old woman with ulcerative colitis and uncommon nasal mucosa pyoderma vegetans . the patient presented to our hospital with symptoms of active colitis and a concomitant 345 cm dermato - mucosal l...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : sepsis is the main cause of mortality in pediatric intensive care units ( picus ) . it is caused by numerous infectious agents , inducing multiple...
### Summary: : backgroundto investigate the prognostic value of procalcitonin ( pct ) , high - sensitivity c - reactive protein ( hs - crp ) , and pancreatic stone protein ( psp ) in children with sepsis.material/methodsa total of 214 patients with sepsis during hospitalization were enrolled . serum levels of pct ,...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : rna can play an important functional role in catalysis , e.g. ribozymes are rna enzymes that cleave rna phosphodiester bonds at specific sites ( 1 )...
### Summary: : rnaomics , analogous to proteomics , concerns aspects of the secondary and tertiary structure , folding pathway , kinetics , comparison , function and regulation of all rna in a living organism . given recently discovered roles played by micro rna , small interfering rna , riboswitches , ribozymes , et...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : central neuropathic pain ( central pain ) is pain caused by a disease or lesion in the central nervous system . central pain develops in about 8% ...
### Summary: : central neuropathic pain ( central pain ) is treated with antidepressants , various anticonvulsants , opioids , and cannabinoids , but in many cases treatment is insufficient and associated with a range of side - effects . this review addresses a new treatment for neuropathic pain , the anticonvulsan...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : toxic cyanobacterial blooms in eutrophic lakes , ponds , and reservoirs are a common occurrence around the world [ 13 ] . cyanobacteria of the gen...
### Summary: : for the first time a microcystin - degrading bacterium ( nv-3 isolate ) has been isolated and characterized from a nz lake . cyanobacterial blooms in new zealand ( nz ) waters contain microcystin ( mc ) hepatotoxins at concentrations which are a risk to animal and human health . degradation of mcs ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : pancreatic heterotopia is defined as the presence , outside its usual location , of pancreatic tissue which lacks anatomical and vascular continuity...
### Summary: : heterotopic , aberrant or ectopic pancreas is defined as the presence of pancreatic tissue in topographic anomaly , with no anatomical , neural or vascular connection to the normal pancreas . it is a rare condition found mainly in stomach , duodenum and jejunum . ileal heterotopic pancreas is an unco...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cytomegalovirus ( cmv ) infection still remains a major cause of morbidity and mortality in allogeneic stem cell transplantation ( sct ) recipients ...
### Summary: : despite the prophylaxis and preemptive strategies using potent antiviral agents , cytomegalovirus ( cmv ) remains a major infectious cause of morbidity and mortality in allogeneic stem cell transplantation ( sct ) recipients . delayed immune reconstitution after sct , such as cord blood and t - cell de...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : lateral gene transfer ( lgt ) is a phenomenon central to prokaryotic evolution and adaptation . with the increasing use and sophistication of genomi...
### Summary: : lateral gene transfer ( lgt ) impacts on the evolution of prokaryotes in both the short and long - term . the short - term impacts of mobilized genes are a concern to humans since lgt explains the global rise of multi drug resistant pathogens seen in the past 70 years . however , lgt has been a fea...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : diabetes mellitus ( dm ) is a clinical syndrome characterized by hyperglycemia because of absolute or relative deficiency of insulin . the diagnosis...
### Summary: : aims and objectives : the purpose of this study was to estimate and assess any correlation between random capillary blood glucose ( rcbg ) and unstimulated whole salivary glucose ( uwsg ) , as well as to estimate various salivary parameters , such as flow rate , ph , buffering capacity , and the influe...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : due to increasing life expectancy of the dentition , older adults are experiencing root caries and gingival recession , putting them at even higher ...
### Summary: : root caries is one of the most significant dental problems among older adults today . many studies have demonstrated that older adults are at greater risk for developing root caries . here we examine what risk factors older adults are prone to and explain how they contribute to higher rates of oral...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : overweight and obesity is an increasing problem globally . the prevalence is often estimated by body mass index ( bmi ; weight in kg divided by squa...
### Summary: : backgroundbody mass index ( bmi ) based on self - reported height and weight has been criticized as being biased because of an observed tendency for overweight and obese people to overestimate height and underestimate weight , resulting in higher misclassification for these groups . we examined the v...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the functions of the salivary glands are controlled by the autonomic nervous system and influenced by the sensory nervous system . when parasympat...
### Summary: : cevimeline is a novel muscarinic acetylcholine receptor agonist currently being developed as a therapeutic agent for xerostomia . we examined the effects of cevimeline on salivary and plasma levels of substance - p- ( sp- ) , calcitonin - gene - related - peptide- ( cgrp- ) , and vasoactive - intesti...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the technique of lymphatic mapping and sentinel lymph node biopsy ( slnb ) has emerged in the last two decades as a minimally invasive approach to e...
### Summary: : the american society of clinical oncology guidelines recommend sentinel lymph node biopsy ( slnb ) for all patients with melanoma tumors of intermediate thickness ( between 1 and 4 mm ) . in case of patients with thick melanoma tumors ( > 4 mm ) , slnb may be recommended as well , for staging purposes ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the chronic diseases like cardiovascular diseases , diabetes and cancer contributes to almost half of the all - cause mortality in india . weighted ...
### Summary: : since a very long time , a significant number of patients have been seeking treatment at complementary and alternative medicine health facilities , but the disease burden at these facilities has never been assessed and documented . present cross - sectional study was carried out at ayurvedic tertiary...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : proinflammatory cytokines ( il-1 , il-6 , and tnf- ) may significantly influence the development of obesity and concomitant disorders such as type 2...
### Summary: : backgroundthe development of obesity and related disorders , e.g. , type ii diabetes ( t2d ) , hypertension , and metabolic disturbances is strongly related to increased levels in proinflammatory cytokines ( il-1 , il-6 , and tnf- ) . both il-6 and tnf- are secreted by adipocytes and their concentrat...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the empa - reg outcome trial ( clinicaltrials.gov identifier , nct01131676 ) recently announced the effects of empagliflozin on the cardiovascular o...
### Summary: : this article discusses the recently published empa - reg outcome trial , which assessed cardiovascular outcomes with empagliflozin therapy in persons with type 2 diabetes mellitus and coexisting cardiovascular disease . the article describes the background and challenges of modern cardiovascular outc...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : primary neuroendocrine carcinoma ( nec ) of the breast is a rare distinct clinicopathological entity , comprising 0.5 - 2% of breast carcinomas worl...
### Summary: : cases of primary neuroendocrine carcinoma ( nec ) of the breast have been reported , though rare . we report the case of a 45-year - old woman presented with jaundice and evaluated to have liver metastasis from neuroendocrine origin . she underwent whole body positron emission tomography / computed...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : malignant unilateral or bilateral ureteral obstruction may be secondary to direct tumor invasion , extrinsic compression , or encasement by metastat...
### Summary: : purposewe assessed the efficacy and safety of insertion of a polytetrafluoroethylene membrane - covered self - expandable metallic stent ( uventa stent ) for palliation of malignant ureteral obstruction on the basis of our early results.materials and methodseighteen patients underwent uventa stent inse...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : typically , using standard assessment criteria , approximately 50 to 100 channel targets are detected in chondrocytes . not surprisingly the datas...
### Summary: : to date , a range of ion channels have been identified in chondrocytes using a number of different techniques , predominantly electrophysiological and/or biomolecular ; each of these has its advantages and disadvantages . here we aim to compare and contrast the data available from biophysical and mic...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic obstructive pulmonary disease ( copd ) is characterized by progressive and partially reversible airflow limitation , and it is among the lea...
### Summary: : purposewe investigated the association between cognitive impairment and chronic obstructive pulmonary disease ( copd ) , taking into account demographic and clinical variables evaluated during routine practice.patients and methodswe performed a post hoc analysis of a cross - sectional study that includ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : intestinal helminths are among the most common and widespread of human infections , contributing to poor nutritional status , anemia and impaired gr...
### Summary: : backgroundthe incidence and hematological effects of helminth infection during pregnancy were investigated among pregnant women in isiala , mbano , southeast nigeria.methods:totally 282 pregnant women were enlisted for the study between october 2011 and september 2012 . stool samples were examined fo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : soft tissue sarcomas are very rare tumors ; however , there are many histologic subtypes . among those subtypes , furthermore , among sarcomas ori...
### Summary: : retroperitoneal liposarcoma is a rare tumor . the dimension and weight of liposarcoma are variable ; those over 20 kg are called giant liposarcoma. herein , we report giant retroperitoneal liposarcoma measuring 45 cm in diameter and 25 kg in weight encasing the entire left kidney and adherent to ad...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : eight members with schwannomatosis from four consecutive generations of a family included in this study were selected according to the following cri...
### Summary: : purpose : schwannomatosis , a subtype of neurofibromatosis , is characterized by multiple benign , nonvestibular , nonintradermal schwannomas . although the tumor suppressor smarcb1 gene has been frequently identified as the underlying genetic cause of half of familial and ~10% of sporadic schwannoma...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : emergence of bacterial resistance to many different antibiotics is considered as a great concern in human health . pseudomonas aeruginosa ( pa ) h...
### Summary: : background and objectives : pseudomonas aeruginosa ( pa ) is one of the most important causes of nosocomial infections and has an intrinsic resistance to many antibiotics . among all the resistance - nodulation - division ( rnd ) pumps of p. aeruginosa , mexab - oprm is the first efflux pump found to...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : severe sepsis and septic shock are common causes of mortality and morbidity in an intensive care unit ( icu ) setting . the endotoxin ( lipopolysa...
### Summary: : background and aims : severe sepsis and septic shock are common causes of mortality and morbidity in an intensive care unit setting . endotoxin , derived from the outer membranes of gram - negative bacteria , is considered a major factor in the pathogenesis of sepsis . this study investigated the e...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a recent report published by the american association of colleges of nursing ( aacn ) noted that over 67,000 qualified applicants were not accepted ...
### Summary: : the shortage of nursing faculty has contributed greatly to the nursing workforce shortage , with many schools turning away qualified applicants because there are not enough faculty to teach . despite the faculty shortage , schools are required to admit more students to alleviate the nursing shortage . ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : ameloblastoma is seen to have a benign appearance on histology , irrespective of its variable clinical behavior . microscopically various patterns...
### Summary: : ameloblastoma is a slow growing odontogenic epithelial tumor of jaw . it accounts for 1% of all tumors and cysts arising in maxilla and mandible . although it is locally invasive and has a marked tendency to recur , metastasis is rare . of the various histological patterns of ameloblastoma , the ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : mesenteric and omental mesothelial cysts are responsible for only 1 in 100,000 of adult hospital admissions , and are thus left low on the list of d...
### Summary: : highlightsmesenteric cystic masses account for a very small fraction of abdominal pain cases.symptoms arise likely as a result of mass effect , even when these lesions are small.on detection of these lesions by imaging , it is important to exclude neuroendocrine tumors.complete surgical excision is cur...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in the past , a number of studies1,2 have given insight into the epidemiology of primary open - angle glaucoma . for caucasians , it is estimated ...
### Summary: : the purpose of our systematic review is to document the adverse events that follow phacoemulsification in eyes with trabeculectomy due to glaucoma and to determine whether phacoemulsification jeopardizes the survival of the trabeculectomy . our research was based on english- and non - english - langu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in the united states , 166 million dental restorations were placed in 2005,1 and clinical studies suggest that more than half were replacements for ...
### Summary: : restoring posterior teeth with resin - based composite materials continues to gain popularity among clinicians , and the demand for such aesthetic restorations is increasing . indeed , the most common aesthetic alternative to dental amalgam is resin composite . moderate to large posterior composi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : sarcoidosis is a rare condition with a prevalence of 4.46.3 patients per 100,000 personyears in australia , a figure similar to that of the united s...
### Summary: : key clinical messagesarcoidosis is a diagnosis that should be considered in patients receiving interferon therapy , who present with anemia and multiorgan dysfunction regardless of the duration of their treatment . when sarcoidosis is suspected , bone marrow biopsy should be considered especially for c...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : apratoxins are potent cytotoxins derived from marine cyanobacteria . because of their biological activity and intriguing structures , we recen...
### Summary: : apratoxins are cytotoxic natural products originally isolated from marine cyanobacteria that act by preventing cotranslational translocation early in the secretory pathway to downregulate receptor levels and inhibit growth factor secretion , leading to potent antiproliferative activity . thro...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : seizure in patients with systemic lupus erythematosus ( sle ) is considered to be one of the major manifestations of the disease . the prevalence ...
### Summary: : a 51-yr - old female was referred to our outpatient clinic for the evaluation of generalized edema . she had been diagnosed with idiopathic thrombocytopenic purpura ( itp ) . she had taken no medicine . except for the itp , she had no history of systemic disease . she was diagnosed with systemic ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : stress urinary incontinence ( sui ) , pelvic organ prolapse , and chronic pelvic pain are frequent complaints of women in perimenopause and menopaus...
### Summary: : objectivesin physiotherapeutic practice , special attention is being given to the reciprocal anatomical , physiological , and biomechanical relationship of the pelvis and the structures connected to it . however , the scientific literature shows mainly the theoretical information about their mutual c...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : thermal spring 's microbiomes have been in attention of the scientific community since past few decades . these springs , being hub of diverse ...
### Summary: : insights about the distribution of the microbial community prove to be the major goal of understanding microbial ecology which remains to be fully deciphered . hot springs being hub for the thermophilic microbiota attract the attention of the microbiologists . deulajhari hot spring cluster is locat...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : an article recently published demonstrated the efficacy of eculizumab in the treatment of children with severe hematopoietic stem cell transplantati...
### Summary: : a 30-year - old man with acquired aplastic anemia underwent an hla - identical bone marrow transplant . he developed a grade iii acute graft versus host disease ( gvhd ) refractory to various lines of treatment . on post - transplant day 196 , he was diagnosed with stem cell transplantation - assoc...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : numerous medical conditions are known to produce psychotic symptoms that resemble schizophrenia , including metabolic and neurological disorders ( c...
### Summary: : schizophrenia - like illnesses occur in a variety of medical and neurological conditions but to date have not been described in association with aceruloplasminemia . aceruloplasminemia is an autosomal recessive disorder of iron metabolism which leads to iron deposition in the basal ganglia , thalamus...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : we screened a collection of sponge- and marine fungi - derived extracts ( n = 2500 ) and pure compounds ( n = 400 ) using a primary cell - based...
### Summary: : an extract of humicola fuscoatra ( ucsc strain no . 108111a ) was shown to reactivate latent hiv-1 expression in an in vitro model of central memory cd4 + t cells . we report the bioassay - guided isolation and structure determination of several resorcyclic acid lactones , including four kn...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : warfarin is highly effective in reducing stroke risk in patients with atrial fibrillation ( af ) . however , using warfarin is not easy ; effort i...
### Summary: : atrial fibrillation ( af ) is an emerging epidemic in both high - income and low - income countries , mainly because of global population aging . stroke is a major complication of af , and af - related ischemic stroke is more disabling and more fatal than other types of ischemic stroke . however , ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the author has not received any funding or benefits from industry or elsewhere to conduct this study .
### Summary: : there remain tremendous opportunities to improve the stability and safety of american health care . within this context , residents and residency programs face two essential questions : how to reduce the risk to patients resulting from resident inexperience , and how to change our programs to create ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : attention to women 's health has evolved from a limited focus on reproductive and breast health to encompassing all aspects of health from birth thr...
### Summary: : abstractthe national institutes of health 's ( nih ) commitment to improving health outcomes for women and men through rigorous science has been compromised by the lack of basic science evidence obtained from female animals . to correct this limitation , in june 2015 the nih announced expectations th...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : thymic neuroendocrine ( ne ) tumors associated with multiple endocrine neoplasia type 1 ( men-1 ) are rare , variably documented in 1 - 8% cases . ...
### Summary: : thymic neuroendocrine ( ne ) tumors are a rare manifestation of multiple endocrine neoplasia syndrome type 1 ( men-1 ) . they are malignant and aggressive tumors and form a major cause of mortality in men-1 . transcervical thymectomy ( tct ) at the time of parathyroid surgery for primary hyperparat...