title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Giant, congenital folliculosebaceous cystic hamartoma: a case against a pathogenetic relationship with trichofolliculoma. | Folliculosebaceous cystic hamartoma (FSCH) is a rare cutaneous hamartoma consisting of dilated folliculosebaceous units invested in mesenchymal elements. These solitary lesions typically affect adults, have a predilection for the central face or scalp, and remain less than 1.5 cm in greatest dimension. Although giant F... | 18,806,500 |
The clinical value of B-type natriuretic peptide (BNP) in predicting nocturnal low back pain in patients with concurrent lumbar spinal stenosis and cardiopulmonary dysfunction (Vesper's Curse): a clinical case series. | To test the hypothesis that B-type natriuretic peptide is elevated in patients with both lumbar spinal stenosis and cardiopulmonary dysfunction who reported sleep-interrupting low back pain, the "symptomatic group," as compared with an analogous cohort not experiencing nocturnal low back pain, i.e., the "control group.... | 18,806,508 |
Blood pressure reference values in adolescents: methodological aspects and suggestions for Northern Europe tables based on the Nord-Trøndelag Health Study II. | The secular weight increase in European and US adolescents and the increasing use of oscillometric devices pose a problem to decide on normative blood pressure levels. We studied how biological and statistical aspects influence standards, and suggest new Northern Europe reference tables. All adolescents of Nord-Trøndel... | 18,806,614 |
Ouabain treatment increases nitric oxide bioavailability and decreases superoxide anion production in cerebral vessels. | Chronic administration of ouabain induces hypertension and increases the contribution of nitric oxide to vasoconstrictor responses in peripheral arteries. The aim of this study was to analyse whether ouabain treatment alters the nitric oxide bioavailability in cerebral arteries. Basilar arteries from control and ouabai... | 18,806,618 |
Impaired angiotensin II-extracellular signal-regulated kinase signaling in failing human ventricular myocytes. | Angiotensin II was reported to induce insulin-like growth factor-I and endothelin-1 gene expression and peptide release by ventricular cardiomyocytes. However, the progression from cardiac hypertrophy to failure in humans is characterized by a reduced myocyte expression of insulin-like growth factor-I and endothelin-1,... | 18,806,628 |
Reconstruction of the tarsus-conjunctival layer using a venous wall graft. | The repair of full-thickness defects of the eyelids poses a challenge, because the reconstruction of the tarsus-conjunctival layer often results in aesthetically and functionally unsatisfactory outcomes. The authors' aim was to create a new method to repair large tarsus-conjunctival losses and to examine the outcomes o... | 18,806,653 |
Orbital hyperostosis following exenteration. | To report the development of unilateral, diffuse hyperostosis of orbital bones in 3 postexenteration patients. Three advanced cases of periorbital and orbital malignancies are presented, and their clinical, radiologic, and histopathologic features are reviewed. Postexenteration CT showed thickened orbital walls in all ... | 18,806,659 |
The levator aponeurosis exposed. | A case of bilateral upper eyelid ptosis in an HIV-infected patient with severe antiretroviral-associated facial lipodystrophy is presented. The features, treatment, and outcome are discussed. Dehiscence of the levator aponeurosis may be directly associated with highly active antiretroviral therapy-induced lipodystrophy... | 18,806,677 |
Population pharmacokinetics of atazanavir in human immunodeficiency virus-infected patients. | The aim of this study was to determine the population pharmacokinetic (PK) parameters of atazanavir in adult human immunodeficiency virus-infected patients to build up a Bayesian strategy for dosage regimen individualization. This was an observational study of patients treated with the once-daily regimen atazanavir ass... | 18,806,695 |
Clinical significance of a CYP2D6 poor metabolizer--a patient with schizophrenia on risperidone treatment. | A case of a 46-year-old woman with schizophrenia who was treated with risperidone and followed up for 1 year is reported. She was genotyped as a CYP2D6 poor metabolizer (PM): CYP2D6-4*/*6, which was confirmed by a dextromethorphan (DM) test (metabolic ratio = 5.8). Genotypes of ABCB1 (MDR1) were 2677TT and 3435TT. Beca... | 18,806,696 |
Pharmacodynamics of mycophenolic acid in CD4+ cells: a single-dose study of IMPDH and purine nucleotide responses in healthy individuals. | Mycophenolate mofetil is used in rejection prophylaxis after allograft transplantation. The highly variable pharmacokinetics and pharmacodynamics (PD) of the active moiety mycophenolic acid (MPA) render this drug attractive for therapeutic monitoring. The aim of this study was to characterize the exposure-response rela... | 18,806,697 |
Lessons learned from studies of the natural history of diabetic nephropathy in young type 1 diabetic patients. | Diabetic Nephropathy (DN) remains the leading cause of end stage renal disease (ESRD) in the Western world, responsible for nearly half of all new ESRD cases in the USA (1). DN develops in 20-25% of patients with type 1 diabetes (T1DM) (2) and, although risk of DN is clearly related to glycemic control (3,4), other var... | 18,806,710 |
Prevention of type 2 DM: implications for adolescents and young adults. | Type 2 Diabetes has reached epidemic proportions among adults in the USA and worldwide. With the rising epidemic of obesity among children and adolescents, a parallel epidemic of type 2 diabetes is also observed in this patient population. Control of diabetes and its complications, mainly cardiovascular disease has bee... | 18,806,714 |
Celiac disease in African American children with type 1 diabetes mellitus in inner city Brooklyn. | There is a strong evidence for association between type 1 diabetes and Celiac Disease. Up to 8% of patients with type1 diabetes have characteristic features of CD on small intestinal biopsy. Type 1 diabetics who have HLA DQ2 or DQ8 are at risk for CD. However most of this data is from studies conducted in Europe, with ... | 18,806,716 |
Early detection and treatment of diabetic nephropathy. | Renal involvement in diabetes, known as diabetic nephropathy (DN), is a progressive disease and occurs as a result of direct and indirect effects of hyperglycemia. DN is a serious public health concern because it is the leading cause of end stage renal disease (ESRD) in most developed countries and is associated with i... | 18,806,717 |
Effects of PDT with 5-aminolevulinic acid and chitosan on Walker carcinosarcoma. | Porphyrins and new chitosan hydrogels based composites with porphyrins are used as active cytotoxic antitumor agents in photodynamic therapy (PDT). The present study evaluates the effects of photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA) and 5-ALA associated with chitosan (CS) using Walker carcinosarcoma... | 18,806,744 |
Alterations of constitutive pericentromeric heterochromatin in lymphocytes of cancer patients and lymphocytes exposed to 5-azacytidine is associated with DNA-hypomethylation. | DNA hypomethylation plays a key role in carcinogenesis. The malignant transformation of cells as well as tumor progression is accompanied with increasing DNA hypomethylation in cancer cells. Nevertheless, the evolution of dis-epigenetic genomic alteration in the somatic cellular malignant transformation has not yet bee... | 18,806,747 |
No association between the Arg194Trp and Arg399Gln polymorphisms of the XRCC1 gene and colorectal cancer risk and progression in a Polish population. | The risk of sporadic colorectal cancer can be associated with environmental and lifestyle factors that may be sources of physical and chemical carcinogens, modulated by products of many low penetrance genes. Polymorphisms of DNA repair genes may influence variation in individual DNA repair capacity, which is crucial fo... | 18,806,752 |
Bcl-2 inhibitors: small molecules with a big impact on cancer therapy. | Despite tremendous advances over the last 15 years in understanding fundamental mechanisms of apoptosis, this has failed to translate into improved cancer therapy for patients. However, there may now be light at the end of this long tunnel. Antiapoptotic Bcl-2 family members may be divided into two subclasses, one comp... | 18,806,758 |
Ocular air gun injuries: a one-year surveillance study in the UK and Eire (BOSU). 2001-2002. | The vulnerability of the eye means that ocular air gun injuries figure prominently in the medical literature. This Study reports the results of the first ocular air gun injury surveillance study. Ocular air gun injuries were reported to the British Ophthalmic Surveillance Unit (BOSU; United Kingdom and Eire) for the pe... | 18,806,762 |
Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis. | The ability to cross host barriers is an essential virulence determinant of invasive microbial pathogens. Listeria monocytogenes is a model microorganism that crosses human intestinal and placental barriers, and causes severe maternofetal infections by an unknown mechanism. Several studies have helped to characterize t... | 18,806,773 |
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. | MicroRNAs (miRNAs) are short RNAs that direct messenger RNA degradation or disrupt mRNA translation in a sequence-dependent manner. For more than a decade, attempts to study the interaction of miRNAs with their targets were confined to the 3' untranslated regions of mRNAs, fuelling an underlying assumption that these r... | 18,806,776 |
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. | Here we describe two families with retinitis pigmentosa, a hereditary neurodegeneration of rod and cone photoreceptors in the retina. Affected family members were homozygous for loss-of-function mutations in IDH3B, encoding the beta-subunit of NAD-specific isocitrate dehydrogenase (NAD-IDH, or IDH3), which is believed ... | 18,806,796 |
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. | Increased lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) activity is associated with increased risk of cardiac events, but it is not known whether Lp-PLA(2) is a causative agent. Here we show that selective inhibition of Lp-PLA(2) with darapladib reduced development of advanced coronary atherosclerosis in diabet... | 18,806,801 |
On contemporaneous controls, unlikely outcomes, boxes and replacing the 'Student': good statistical practice in pharmacology, problem 3. | This paper is intended to assist pharmacologists to make the most of statistical analysis and avoid common errors. A scenario, in which an experimenter performed an experiment in two separate stages, combined the control groups for analysis and found some surprising results, is presented. The consequences of combined c... | 18,806,810 |
Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout. | The alpha(1L)-adrenoceptor has pharmacological properties that distinguish it from three classical alpha(1)-adrenoceptors (alpha(1A), alpha(1B) and alpha(1D)). The purpose of this was to identify alpha(1L)-adrenoceptors in mice and to examine their relationship to classical alpha(1)-adrenoceptors. Radioligand binding a... | 18,806,813 |
Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease. | Experimental and clinical investigations have revealed that statins can downregulate both acute and chronic inflammatory processes. Whether statins express anti-inflammatory activities in the treatment of Crohn's disease is unknown. Ten patients were given 80 mg atorvastatin once daily for 13 weeks and then followed up... | 18,806,816 |
Outcome following unrelated cord blood transplant in 136 patients with malignant and non-malignant diseases: a report from the Australian and New Zealand children's haematology and oncology group. | Unrelated umbilical cord blood (UCB) is an alternative stem cell source for paediatric patients lacking a matched related or unrelated marrow donor. We report the results of all paediatric unrelated UCB transplants performed in Australia and New Zealand over a 10-year period. A total of 135 patients were transplanted, ... | 18,806,837 |
Simultaneous measurement of multiparameters using a Sagnac interferometer with polarization maintaining side-hole fiber. | A Sagnac interferometer with a section of a polarization maintaining side-hole fiber for multiparameter measurement is proposed. The sensor was experimentally demonstrated to be sensitive to torsion, temperature, and longitudinal strain, simultaneously. The birefringence in the investigated side-hole fiber is induced s... | 18,806,840 |
Refractive index and extinction coefficient determination of an absorbing thin film by using the continuous wavelet transform method. | We present the continuous wavelet transform (CWT) method for determining the dispersion curves of the refractive index and extinction coefficient of absorbing thin films by using the transmittance spectrum in the visible and near infrared regions at room temperature. The CWT method is performed on the transmittance spe... | 18,806,848 |
Thin-type integral imaging method with an organic light emitting diode panel. | A thin and lensless two-dimensional (2D) to three-dimensional (3D) convertible display based on integral imaging using an organic light emitting diode (OLED) panel as a direct emissive light source is proposed with improved optical efficiency. A point light source array for 2D-3D convertible display is formed on the su... | 18,806,853 |
Comparative evaluation of two simple diffuse reflectance models for biological tissue applications. | We present a comparative evaluation of two simple diffuse reflectance models for biological tissue applications. One model is based on a widely accepted and used in biomedical optics implementation of diffusion theory, and the other one is based on a semiempirical approach derived from basic physical principles. We tes... | 18,806,859 |
Proteomic detection of changes in protein expression induced by cordycepin in human hepatocellular carcinoma BEL-7402 cells. | The nucleoside analogue cordycepin (3 '-deoxyadenosine, 3 '-dA), one of the components of Cordyceps militaris, has been shown to inhibit the growth of various tumor cells. However, the probable mechanism is still obscure. In this study, the inhibition of cell growth and changes in protein expression induced by cordycep... | 18,806,893 |
Antifungal prophylaxis in adult hematopoietic stem cell transplant recipients. | Invasive fungal infections (IFIs) are a frequent, costly and potentially life-threatening complication in hematopoietic stem cell transplant (HSCT) recipients. Most prevalent among the causative pathogens are Candida spp. and Aspergillus spp. Risk factors that further increase the risk of IFIs in this patient populatio... | 18,806,902 |
Constriction of the levator hiatus during instruction of pelvic floor or transversus abdominis contraction: a 4D ultrasound study. | A new theory claims that the pelvic floor muscles (PFM) can be trained via the transversus abdominis (TrA). The aim of the present study was to compare the effect of instruction of PFM and TrA contraction on constriction of the levator hiatus, using 4D perineal ultrasonography. Thirteen women with pelvic organ prolapse... | 18,806,912 |
Factors associated with choice of psychotropic drugs used for intentional drug overdose. | Knowledge of the factors influencing the choice of drugs used for intentional drug overdose (IDO) may allow the reduction of IDO lethality. To assess with which frequency subjects with intentional overdose of psychotropic drugs ingest their own psychotropic drug treatment, and whether prescription of a drug may be a fa... | 18,806,918 |
Autoreactive T-cell responses to myeloperoxidase in patients with antineutrophil cytoplasmic antibody-associated vasculitis and in healthy individuals. | The aim of this study was to evaluate the characteristics of autoreactive T cells to myeloperoxidase (MPO) in patients with MPO-antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Peripheral blood T cells from 15 patients with MPO-ANCA-associated vasculitis and 14 healthy individuals were cultured with th... | 18,806,928 |
Morin protects acute liver damage by carbon tetrachloride (CCl(4)) in rat. | The purpose of this study was to investigate possible beneficial effects of morin on CCl(4)-induced acute hepatotoxicity in rats. Rats received a single dose of CCl(4) (150 microL/100 g 1:1 in corn oil). Morin treatment (20 mg/kg) was given at 48, 24, and 2 h before CCl(4) administration. CCl(4) challenge elevated seru... | 18,806,959 |
Determination of enantiomeric impurity of etodolac by capillary electrophoresis using (2-hydroxypropyl)-beta-cyclodextrin. | A capillary electrophoresis method was developed to determine the impurity of etodolac enantiomers. (2-Hydroxypropyl)-beta-cyclodextrin (HP-beta-CD) was used as a chiral selector and ketoprofen as an internal standard to improve the peak area precision. The seperation of the etodolac enantiomers was achived within 35 m... | 18,806,967 |
[Reticular erythematous plaques]. | Reticular erythematous mucinosis (REM) syndrome primarily affects young women; the skin lesions usually appear on the chest and upper back. REM is diagnosed on the basis of the clinical picture and histological findings. REM syndrome is often associated with lupus erythematosus tumidus. Both diseases respond well to tr... | 18,806,970 |
[Forced sterilisation of the hereditary deaf in the Third Reich : Its reflection in the scientific ENT literature.] | BACKGROUND: The Law for the Prevention of Genetically Diseased Offspring (enacted in Germany in 1934 and in Austria in 1940) allowed the forced sterilisation of people with hereditary disorders, including hereditary deafness. Doctors were required to register their patients who qualified under the Law and to cooperate ... | 18,806,972 |
Separation and characterization of aluminium malate species by ion chromatography. | Aluminium malate complexes have a high relevance in biological systems. The anionic species present in an aqueous aluminium malate mixture can be investigated by ion chromatography coupled online with inductively coupled plasma atomic emission spectroscopy. As malic acid is a chiral ligand, the experiments were carried... | 18,807,016 |
Abciximab for thrombolysis during intracranial aneurysm coiling. | Thrombotic events are a common and severe complication of endovascular aneurysm treatment with significant impact on patients' outcome. This study evaluates risk factors for thrombus formation and assesses the efficacy and safety of abciximab for clot dissolution. All patients treated with abciximab during (41 patients... | 18,807,025 |
Modic changes in vertebral endplates: a comparison of MR imaging and multislice CT. | This paper aims to evaluate the presence of endplate sclerosis in different types of Modic changes and to assess the capability of MRI in detecting endplate sclerosis within these changes. The lumbar spines (L3-S1) of 70 patients were retrospectively reviewed to determine Modic changes and disc degeneration from MRI an... | 18,807,028 |
[Early loss of heterozygosity on chromosome arm 16q in flat epithelial atypia of the breast. Detection by microsatellite analyses]. | With the improvement of breast carcinoma screening, pre-malignant cell lesions such as flat epithelial atypia (FEA) are detected more frequently. Several studies have demonstrated that FEA show features of a ductal neoplasia, but is it really a precursor lesion? We have started a comparative genetic analysis of a panel... | 18,807,038 |
Spiny versus stubby: 3D reconstruction of human myenteric (type I) neurons. | We have compared the three-dimensional (3D) morphology of stubby and spiny neurons derived from the human small intestine. After immunohistochemical triple staining for leu-enkephalin (ENK), vasoactive intestinal peptide (VIP) and neurofilament (NF), neurons were selected and scanned based on their immunoreactivity, wh... | 18,807,064 |
Compartment model of neuropeptide synaptic transport with impulse control. | In this paper a mathematical description of a presynaptic episode of slow synaptic neuropeptide transport is proposed. Two interrelated mathematical models, one based on a system of reaction diffusion partial differential equations and another one, a compartment type, based on a system of ordinary differential equation... | 18,807,067 |
The signal molecule lysophosphatidylcholine in Eschscholzia californica is rapidly metabolized by reacylation. | In cultured cells of California poppy (Eschscholzia californica), lysophosphatidylcholine (LPC) triggers a signal path that finally induces alkaloid biosynthesis. LPC is transiently generated by elicitor-activated phospholipase A(2) of the plasma membrane. Externally added LPC is rapidly acylated by a membrane-bound en... | 18,807,068 |
Our evolving knowledge of the transcriptional landscape. | The development of a genome-scale approach to identification of the 5' ends of capped mRNAs (CAGE) has given new insights into many aspects of mammalian RNApolII transcription control. They include the identification of the minimal initiator motif, the different types of proximal promoter architecture, the promoters of... | 18,807,086 |
End-of-skin grafts in syndactyly release: description of a new flap for web space resurfacing and primary closure of finger defects. | Treatment of syndactyly necessitates creation of neo-web space and separation of fingers. Traditionally, this has been done by use of flaps taken from the dorsum; the resultant raw areas thus created have been managed by use of skin grafts. The classical teaching has been that the separated fingers will need skin graft... | 18,807,092 |
Oxidative stress-induced insulin resistance in skeletal muscle cells is ameliorated by gamma-tocopherol treatment. | Oxidative stress-induced reactive oxygen species are associated with the clinical manifestation of insulin resistance. Evidence suggests that antioxidant treatment may reduce this incidence. This study determined whether glucose oxidase (GO)-induced insulin resistance in cultured skeletal muscle cells could be ameliora... | 18,807,106 |
Associations between maternal closeness, suicidal ideation, and risk behaviors in Cape Town. | Health compromising behaviors, such as smoking and other risk behaviors tend to co-occur, and contribute to the leading causes of preventable death, disease, and disability among adolescents and young adults worldwide. The present study assesses a model of the direct and indirect effects of maternal closeness with suic... | 18,807,110 |
Isolation, characterization and genome sequencing of phage MZTP02 from Bacillus thuringiensis MZ1. | A lysogenic phage, MZTP02, was produced via induction by mitomycin C from Bacillus thuringiensis (B. thuringiensis) strain MZ1. Plaques were about 3 mm in diameter with a small inner zone consisting of new B. thuringiensis colonies. Electron microscopic analysis showed that MZTP02 had a long tail (220 nm x 18 nm) and a... | 18,807,113 |
The role of nuclear factor-kappaB in the effect of angiotensin II in the paraventricular nucleus in protecting the gastric mucosa from ischemia-reperfusion injury in rats. | The purpose of this study was to elucidate the role of nuclear factor kappaB (NF-kappaB) in the development of gastric ischemia-reperfusion (GI-R) injury and in mediating the effects of angiotensin II (Ang II) in the paraventricular nucleus (PVN) on GI-R injury. GI-R injury was induced in rats by clamping the celiac ar... | 18,807,130 |
Efficacy of combination therapy of antiviral and immunosuppressive drugs for the treatment of severe acute exacerbation of chronic hepatitis B. | Patients with severe exacerbation of chronic hepatitis B, sometimes developing into fulminant liver failure, are at high risk for mortality even with antiviral therapy. The efficacy of immunosuppressive therapy in clinically severe exacerbation of chronic hepatitis B has not been well demonstrated. In this study, we ev... | 18,807,133 |
Reduction of retinaldehyde dehydrogenase 1 expression and production in estrogen-induced prolactinoma of rat. | Retinoic acid (RA) plays a critical role in normal development and tissue maintenance and is also a regulatory factor of anterior pituitary cells. We previously demonstrated that a retinoic acid-synthesizing enzyme, retinaldehyde dehydrogenase 1 (RALDH1), is expressed in prolactin cells of adult rats and that estrogen ... | 18,807,137 |
Early childhood adversities and trajectories of psychiatric problems in adoptees: evidence for long lasting effects. | The aim of the present study is to investigate whether early childhood adversities determine the longitudinal course of psychiatric problems from childhood to adulthood; in particular if the impact of early maltreatment on psychopathology decreases as time passes. A sample of 1,984 international adoptees was followed (... | 18,807,165 |
New directions in measuring reactive and proactive aggression: validation of a teacher questionnaire. | The well-known distinction between reactive and proactive aggression is theoretically important but empirically controversial. Recently, aggression researchers have argued that we should separate the form and function of aggression to make a clearer distinction between reactive and proactive aggression. This article de... | 18,807,166 |
Novel SNPs of the bovine LEPR gene and their association with growth traits. | In this study, polymorphism in the bovine LEPR gene exon 4 was detected by PCR-SSCP and DNA sequencing methods in 653 individuals from five Chinese cattle breeds. Two haplotypes (M and N), three observed genotypes (MM, MN, and NN), and five single nucleotide polymorphisms (SNPs) (NC_007301:g.26767T>C, NC_007301:g.26... | 18,807,168 |
Alteration of DBP levels in CSF of patients with MS by proteomics analysis. | The diagnosis of multiple sclerosis (MS) is still challenging recently due to the lack of a specific diagnostic test. Proteomics analysis was applied to biomarkers discovery and their pathways study. First, the proteins of CSF from MS patients and control group were analyzed individually with 2D-DIGE technology (two-di... | 18,807,170 |
p75NTR antagonistic cyclic peptide decreases the size of beta amyloid-induced brain inflammation. | Amyloid beta (Abeta) was shown to bind the 75 kD neurotrophin receptor (p75(NTR)) to induce neuronal death. We synthesized a p75(NTR) antagonistic peptide (CATDIKGAEC) that contains the KGA motif that is present in the toxic part of Abeta and closely resembles the binding site of NGF for p75(NTR). In vivo injections of... | 18,807,174 |
A pilot study on the effects of heart rate variability biofeedback in patients with depression and in healthy subjects. | Decreased vagal activity and increased sympathetic arousal have been proposed as major contributors to the increased risk of cardiovascular mortality in patients with depression. It was aim of the present study to assess the feasibility of using heart rate variability (HRV) biofeedback to treat moderate to severe depre... | 18,807,175 |
A proposed set of ethical practice guidelines in the assessment and treatment of pelvic floor disorders. | The treatment of pelvic floor disorders using biofeedback, behavioral therapies, and other applied psychophysiological treatments has been well documented as effective. Practitioners must take due care to ensure that they practice within the boundaries of what is common practice for their discipline and within the scop... | 18,807,176 |
Pacific Islands families study: intimate partner violence and postnatal depression. | The present study examined the association between maternal intimate partner violence (IPV) and postnatal depression (PND) 6 weeks after giving birth. Data were gathered from the Pacific Islands Families Study. Mothers of a cohort of Pacific infants born in Auckland, New Zealand during 2000 were interviewed 6 weeks aft... | 18,807,186 |
Recursive estimation of transient inhomogeneous zeta potential in microchannel turns using velocity measurements. | In the various biomedical microfluidic devices the target biomolecules are delivered by activating electroosmotic flows. The zeta potential of a microchannel wall, which determines the strength of the electroosmotic flow, is apt to change due to the adhesion of biomolecules such as DNA or protein especially around the ... | 18,807,196 |
The effects of prolonged deep freezing on the biomechanical properties of osteochondral allografts. | Musculo-skeletal allografts sterilized and deep frozen are among the most common human tissue to be preserved and utilized in modern medicine. The effects of a long deep freezing period on cortical bone has already been evaluated and found to be insignificant. However, there are no reports about the influences of a pro... | 18,807,210 |
Posttraumatic vasospasm detected by continuous brain tissue oxygen monitoring: treatment with intraarterial verapamil and balloon angioplasty. | Posttraumatic vasospasm (PTV) is a relatively common event following traumatic brain injury (TBI) that has been strongly correlated with worse neurological outcome in many studies. However, vasospasm continues to be an under-recognized source of secondary injury following TBI, and currently published guidelines do not ... | 18,807,219 |
Use of dynamic susceptibility-contrast MRI (DSC-MRI) to assess perfusion changes in the ipsilateral brain parenchyma from glioblastoma. | We investigated the effect of increased tumor perfusion using dynamic susceptibility-contrast magnetic resonance imaging (DSC-MRI) in glioblastoma (GBM) patients on the surrounding ipsilateral brain tissue with respect to perfusion of the normal, unaffected contralateral brain and of the tumor. DSC-MRI was performed in... | 18,807,224 |
[Tablet splitting: do discount contracts influence prescribing quality?]. | In Germany, about one fourth of all tablets are split before ingestion. Since April 2007, by German law, pharmacists are legally obligated to substitute a prescribed drug for a generic drug, provided the patients' health insurance company has made corresponding contracts with pharmaceutical companies (discount contract... | 18,807,231 |
[Chemical restraints in nursing homes in the federal state Vorarlberg, Austria--an analysis of nursing home documentation according to legal obligation and suggestions for future improvement]. | High prevalence of chemical restraints in nursing homes is being criticised as suboptimal care. According to a new legal act, the Austrian "Heimaufenthaltsgesetz" 2005, nursing homes are obliged to report not only physical restraints but also chemical restraints. Using the Beers criteria we analysed all 78 notification... | 18,807,239 |
[Sudden cardiac death 43 months after fulminant myocarditis and two-peaked myositis in non-typhoid salmonellosis]. | A previously healthy 29-year-old male was hospitalized due to acute myalgia and high temperature following an uncomplicated gastroenteritis. Within 24 hours, he developed life-threatening hemodynamic shock with the need for inotropic support and sustained ventricular tachycardia. Echocardiography and electrocardiogram ... | 18,807,242 |
CD41 Western blotting: a new method to detect platelet adhesion to artificial surfaces used in extracorporeal circulation procedures. | Cardiopulmonary bypass (CPB) surgery is associated with platelet activation and reduced platelet counts due to artificial surface activation of blood elements and non-physiological flow-patterns. As shown in former studies, coating of medical devices can improve hemocompatibility in extracorporeal circulation systems. ... | 18,807,263 |
Bioactive borosilicate glass scaffolds: improvement on the strength of glass-based scaffolds for tissue engineering. | Three-dimensional macroporous scaffolds with the pore size of 200-500 mum were fabricated by replication method using bioactive borosilicate glass from Na(2)O-K(2)O-MgO-CaO-SiO(2)-P(2)O(5)-B(2)O(3) system. The effects of the strength of the strut in reticulated scaffold, as well as the geometrical parameter of the scaf... | 18,807,266 |
The organophosphorous pesticide, fenitrothion, acts as an anti-androgen and alters reproductive behavior of the male three-spined stickleback, Gasterosteus aculeatus. | Fenitrothion (FN) is a widely used organophosphorous pesticide that has structural similarities with the clinical anti-androgen flutamide. The potential for FN to act as an anti-androgen (at exposures of 1, 50, and 200 microg FN/l over a 26-day period) was assessed in male three-spined sticklebacks, Gasterosteus aculea... | 18,807,270 |
Mucinous cystadenoma of the appendix associated with muscular and neuromatous hyperplasia: report of a case. | Mucinous cystadenoma of the appendix is a type of appendiceal mucocele and a rather rare condition usually found incidentally in the course of other abdominal surgery. A previous evaluation of 73 appendiceal mucoceles showed that this disease was often associated with adenocarcinoma and other epithelial atypia. This ob... | 18,807,294 |
Audit of provincial gastroenterology services in the Western Cape. | While disorders such as gastro-oesophageal reflux disease, gastrointestinal (GI) cancers and inflammatory bowel disease are prevalent among all racial groups in the Western Cape, there is little knowledge of local GI service provision. The state of equipment, facilities and staffing is largely unrecorded and to date un... | 18,807,301 |
[Local treatment for persistent inflammatory arthritis of the knee: intra-articular injection of glucocorticoids and bed rest]. | Two studies evaluating treatment options for persistent mono-arthritis are discussed. In one study arthroscopic lavage plus intra-articular glucocorticoids was compared with arthroscopic lavage without glucocorticoids, and with joint aspiration plus glucocorticoids. Both intra-articular glucocorticoids and lavage have ... | 18,807,330 |
Transmission dynamics of Simulium damnosum in rural communities of Akwa Ibom State, Nigeria. | Onchocerciasis is endemic in some parts of Akwa Ibom State, Nigeria. This study describes the entomological parameters of transmission in three rural communities of Akwa Ibom State, prior to ivermectin intervention in 2004. Blackflies were caught using human bait and 90% of the flies were dissected for parity. All paro... | 18,807,379 |
Majority of emergency patients don't understand discharge instructions. | ED managers, responding to a study that showed more than 75% of patients do not understand their discharge instructions, list several options for improving communications. They include: Have several providers discuss with the patient their condition, treatment, and follow-up instructions. Make sure discharge instructio... | 18,807,395 |
Professionalism and coordination: allies or enemies? | Professionalism arose concurrently with coordination policies among service providers and between parents and service providers in deaf education practices. The author examines the effects of professionalism on coordination among service providers from different disciplines (deaf education, speech-language pathology, e... | 18,807,405 |
College and university requirements for teachers of the deaf at the undergraduate level: a twenty-year comparison. | College and university requirements for undergraduate deaf education teacher preparation programs from 1986 and 2006 were compared. Thirty percent fewer undergraduate programs were in existence in 2006 than in 1986. Compared to programs in the 1986-1987 academic year, programs in 2006-2007 placed less emphasis on cours... | 18,807,407 |
Music as a nursing intervention for preterm infants in the NICU. | Although there is general agreement that noise in the neonatal intensive care unit should be reduced, there is controversy about the use of music as a developmental care strategy with prererm infants. Much literature supports using music with preterm infants, indicating that it enhances physiologic and neurobehavioral ... | 18,807,412 |
Predicting attendance at peer-assisted study sessions for statistics: role identity and the theory of planned behavior. | Using a prospective study of 77 1st-year psychology students' voluntary attendance at peer-assisted study sessions for statistics, the authors tested the addition of role identity to the theory of planned behavior. The authors used a revised set of role-identity items to capture the personal and social aspects of role ... | 18,807,422 |
[Mumps in Poland in 2006]. | In 2006, 15,115 cases of mumps were reported in Poland. The incidence (39.6 per 100,000) was considerably lower compared to 2005 (188.5) and to the median incidence in 2000-2004 (104.6). The decrease of mumps incidence in 2006 is related to high coverage of routine two-dose immunisation against measles, mumps and rubel... | 18,807,461 |
[The pathogenesis of uterine hemorrhages in the so-called placental polyps]. | On the basis of histological and immunohistochemical studies of 50 uterine scrapes after abortions and labor due to late bleedings, the authors identified three major types of the so-called placental polyps: (a) preserved villi (56%); (b) clusters of destructive villi (38%); (c) isolated viable cotyledons (6%). Two pat... | 18,807,525 |
[Papillary glioneuronal tumor is a new nosological entity in the WHO classification of central nervous system tumors (2007)]. | The paper describes a case of cystic papillary glioneuronal tumor of the temporal lobe in an 18-year-old girl. It is shown that in addition to the characteristic histological pattern, the diagnosis of this rare neoplasm recently included into the WHO classification text s should be verified by the immunohistological ev... | 18,807,528 |
[Administration of monoclonal antibodies to B-lymphocytes (rituximab) in rheumatoid arthritis in Russia]. | To assess efficacy and tolerance to anti-B-cell drug rituximab in therapy of rheumatoid arthritis (RA) by the data of RF register of this drug. Rituximab was studied in 42 patients with high RA activity. 37 patients received rituximab according to a conventional scheme: 2 intravenous 1000 mg infusions with a 2-week int... | 18,807,543 |
Abutment screw loosening in single-implant restorations: a systematic review. | The purpose of this study was to systematically review clinical studies on the incidence of abutment screw loosening in single-implant restorations with different implant-abutment connection geometries. The literature search was conducted using several electronic databases. Specific terms were used for the database sea... | 18,807,565 |
Impact of ilio-inguinal nerve excision on sexual function in open inguinal hernia mesh repair: a prospective follow-up study. | The aim of this study was to prospectively compare sexual function in patients undergoing inguinal hernia surgical repair with or without excision of the ilio-inguinal nerve. Eighty-four patients (76 males and 8 females) with a unilateral inguinal hernia were enrolled in the study. They underwent an open tension free r... | 18,807,591 |
Sister Joseph's nodule umbilical manifestation of intraperitoneal carcinomatosis. | An umbilical metastasis is universally referred to as a sister Joseph's nodule if it is caused by extensive intraabdominal neoplastic disease. The presence of an umbilical metastasis usually indicates advanced disease, with poor prognosis. We report on a 64-year old women with a umbilical nodule that was at first not r... | 18,807,599 |
Anastomotic leakage of a colorectal anastomosis treated by transanal endoscopic microsurgery. | To report a minimal invasive technique for repairing an anastomotic leakage with Transanal Endoscopic Microsurgery (T.E.M.) without creating a protective ostomy. There are a large number of techniques for the management of anastomotic leakage after colorectal surgery. Depending on the size and location of the disruptio... | 18,807,609 |
[Rupture of the ventral serrate muscles (Flying Scapulas) as a symptom of muscular dystrophy in Holstein-Friesian heifers on a Dutch dairy farm]. | Within a week of being turned out to pasture, 3 of 30 heifers displayed a symptom described in the literature as "Flying Scapulas". The cause of this symptom is severe muscular dystrophy, with subsequent rupture of the ventral serrate muscles. Blood analysis revealed a deficiency of both vitamin E and selenium in all t... | 18,807,612 |
[Observation on the central afferent pathway of "Guanyuan" (CV 4) under normal and pathological states and the influence of electroacupuncture]. | To investigate the afferent pathways of "Guanyuan" (CV 4) under normal and pathological states and to observe the effect of electroacupuncture (EA) on them. Twenty-four female SD rats were randomly divided into normal control (NC), NC + EA, ovariectomy (OVX) and OVX + EA groups, with 6 cases in each. Four weeks after O... | 18,807,714 |
[Utilizing modern technology to promote spread and development of acu-moxibustion learning]. | Nowadays, modern information technology (IT) has been gained great development. How to use the advanced IT to protect, spread and develop Chinese traditional culture of acupuncture is an important topic at the moment. Based on expounding characteristics of modern IT, the present article analyzed its advantages in digit... | 18,807,724 |
[Comparison of therapeutic effects of electroacupuncture treatment of insomnia at different time]. | To compare the therapeutic effects of evening-electroacupuncture (EA) and morning-EA for insomnia. Sixty cases of simple insomnia patients were randomly divided into evening-EA group and morning-EA group, with 30 cases in each. EA (2/100 Hz, 1-3 mA) was applied to Baihui (GV 20), Shenting (GV 24), Touwei (ST 8), Shenme... | 18,807,726 |
Is the quality of life different in patients with active and inactive tuberculosis? | The aim of this study was to evaluate the quality of life (QOL) in outpatients with active and inactive tuberculosis, and to study the relations between QOL and demographic and socio-cultural chracteristics and variables concerning the disease and depression. Included in the present study were 196 active and 108 inacti... | 18,807,744 |
Antioxidant and hepatoprotective activity of tubers of Momordica tuberosa Cogn. against CCl4 induced liver injury in rats. | Hydro alcoholic extract of tubers of M. tuberosa was subjected to preliminary phytochemical screening and evaluated for in vitro and in vivo antioxidant and hepatoprotective activity against CCl4 induced liver damage in rats. Pretreatment with 70% ethanolic extract of M. tuberosa reversed CCl4 induced elevation of leve... | 18,807,754 |
Effect of Bacopa monniera (Linn.) on lipid peroxidation and lipofuscinogenesis in prostate gland of D-galactose induced aging mice, Mus musculus. | The levels of malondialdehyde and lipofuscin pigments were increased in the prostate of D-galactose (0.5 ml/day, sc, for 20 days) induced aging mice. After B. monniera (40 mg/kg body weight for 20 days) ethanol leaf extract administration levels of both the parameters were reduced significantly. The results suggest tha... | 18,807,760 |
Timing of birth related to obstetric practice and neonatal outcome. | Several studies have reported time of birth is associated with differences in obstetric practice. We investigated the relationship between timing of birth and obstetric and neonatal outcomes, to help plan working patterns under European Working Time Directive (EWTD) legislation. This was a retrospective observational s... | 18,807,809 |
Assessment of the value of pelvic ultrasonography in pre-menopausal women with right iliac fossa pain. | The aim of this study was to determine whether ultrasound examination performed in the acute setting can avoid the need for diagnostic laparoscopy in pre-menopausal women presenting with right iliac fossa pain in whom the diagnosis of acute appendicitis is suspected. All female patients aged fifty or under, who present... | 18,807,813 |
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