title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes. | A new form of super-resolution fluorescence microscopy has emerged in recent years, based on the high accuracy localization of individual photo-switchable fluorescent labels. Image resolution as high as 20 nm in the lateral dimensions and 50 nm in the axial direction has been attained with this concept, representing an... | 18,809,508 |
Comparison of three different concentrations of ropivacaine for postoperative patient-controlled thoracic epidural analgesia after upper abdominal surgery. | Previous studies have reported the comparable efficacy of ropivacaine/fentanyl for patient-controlled epidural analgesia (PCEA). In our hospital, three different concentrations of ropivacaine solution (0.1%, 0.15%, 0.2%) in combination with 1 microg/mL fentanyl were available for PCEA. As some studies have reported a m... | 18,809,519 |
Spontaneous intracranial hypotension treated by epidural blood patches. | We present a case of spontaneous intracranial hypotension (SIH) diagnosed from the clinical symptoms and magnetic resonance imaging brain scans. After failure of conservative treatment, and lack of identification of the cerebrospinal fluid leak site, the headache was managed successfully and simply with two application... | 18,809,524 |
Increasing walking in college students using a pedometer intervention: differences according to body mass index. | The researchers assessed the effectiveness of a pedometer intervention and differences in walking behaviors according to body mass index (BMI). Two hundred ninety college students completed the intervention from January to February 2005. Participants wore pedometers 5 days per week for 12 weeks and completed questionna... | 18,809,532 |
Psychosocial factors and low back pain among college students. | The authors evaluated psychosocial factors of stress and their effects on the prevalence of low back pain (LBP) among a population of college students in a major university in Colorado. This was a nested cross-sectional study of 973 respondents who completed the National College Health Assessment survey. The authors ev... | 18,809,536 |
Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression. | Enterococcus faecalis is an intestinal commensal that cannot synthesize porphyrins and only expresses a functional respiratory chain when provided with exogenous haematin. In the absence of haematin, E. faecalis reverts to fermentative metabolism and produces extracellular superoxide that can damage epithelial-cell DNA... | 18,809,545 |
Molecular epidemiology and antimicrobial susceptibilities of 273 exfoliative toxin-encoding-gene-positive Staphylococcus aureus isolates from patients with impetigo in Japan. | The molecular epidemiology and antimicrobial susceptibilities of 273 Staphylococcus aureus isolates positive for the exfoliative toxin-encoding gene obtained from patients with impetigo in Japan in 2006 were studied. The mecA gene was detected in 74 meticillin-resistant S. aureus (MRSA) and 23 meticillin-susceptible S.... | 18,809,554 |
Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability. | The regulation of the synthesis of the endothelial-derived vasoconstrictor endothelin-1 (ET-1) is a complex process encompassing transcriptional as well as mRNA stability mechanisms. We have described recently the existence of a mechanism for the control of ET-1 expression based on the mRNA-destabilizing capacity of sp... | 18,809,573 |
Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway. | Mitogen-activated protein kinases (MAPKs) are integral to the mechanisms by which cells respond to physiological stimuli and a wide variety of environmental stresses. In Caenorhabditis elegans, the stress response is controlled by a c-Jun N-terminal kinase (JNK)-like mitogen-activated protein kinase (MAPK) signaling pa... | 18,809,575 |
Dissection of the molecular defects caused by pathogenic mutations in the DNA repair factor XPC. | XPC is responsible for DNA damage sensing in nucleotide excision repair (NER). Mutations in XPC lead to a defect in NER and to xeroderma pigmentosum (XP-C). Here, we analyzed the biochemical properties behind mutations found within three patients: one amino acid substitution (P334H, XP1MI, and GM02096), one amino acid ... | 18,809,580 |
Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups. | Adjuvant chemotherapy for resected non-small-cell lung cancer (NSCLC) is now accepted on the basis of several randomized clinical trials (RCTs) that demonstrated improved survival. Although there is strong evidence that adjuvant chemotherapy is effective in stages II and IIIA NSCLC, its utility in stage IB disease is u... | 18,809,614 |
An investigation of the effects of music on anxiety and pain perception in patients undergoing haemodialysis treatment. | This study aimed to investigate the effects of preferred music listening on anxiety and pain perception in patients undergoing haemodialysis. A two group experimental design was used. Sixty people diagnosed with end stage renal failure undergoing haemodialysis treatment participated in this study. Preferred music liste... | 18,809,642 |
Communicating about self and others within an online support group for women with breast cancer and subsequent outcomes. | Research suggests communicating too much about one's self within an online support group may amplify breast cancer patients' focus on their own problems and exacerbate negative emotions while focusing on others may have the opposite effects. This study explored how pronoun usage within an online support group was assoc... | 18,809,644 |
Peer crowd identification and indoor artificial UV tanning behavioral tendencies. | In this study, the relation between peer crowd identification and indoor tanning behavioral tendencies was examined. Participants were 174 undergraduate students at a large university in the USA. Results indicated peer crowd identification was significantly associated with indoor artificial UV tanning behavioral tenden... | 18,809,645 |
Diabetes mellitus: considerations for dentistry. | The connection between oral health and systemic health is bidirectional; systemic illnesses, especially metabolic disorders, affect oral health, and it appears that oral health may affect systemic health. In this review, the authors outline the basic principles behind diabetes mellitus (DM) and provide some tips to hel... | 18,809,649 |
The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4. | The obligate intracellular parasite Toxoplasma gondii infects warm-blooded animals throughout the world and is an opportunistic pathogen of humans. As it invades a host cell, Toxoplasma forms a novel organelle, the parasitophorous vacuole, in which it resides during its intracellular development. The parasite modifies ... | 18,809,661 |
Filamin B mediates ICAM-1-driven leukocyte transendothelial migration. | During inflammation, the endothelium mediates rolling and firm adhesion of activated leukocytes. Integrin-mediated adhesion to endothelial ligands of the Ig-superfamily induces intracellular signaling in endothelial cells, which promotes leukocyte transendothelial migration. We identified the actin cross-linking molecu... | 18,809,679 |
Interaction between the C termini of Alg13 and Alg14 mediates formation of the active UDP-N-acetylglucosamine transferase complex. | The second step of eukaryotic N-linked glycosylation in endoplasmic reticulum is catalyzed by an UDP-N-acetylglucosamine transferase that is comprised of two subunits, Alg13 and Alg14. The interaction between Alg13 and 14 is crucial for UDP-GlcNAc transferase activity, so formation of the Alg13/14 complex is likely to ... | 18,809,682 |
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. | The current goal of diabetes therapy is to reduce time-averaged mean levels of glycemia, measured as HbA1c, to prevent diabetic complications. However, HbA1c only explains <25% of the variation in risk of developing complications. Because HbA1c does not correlate with glycemic variability when adjusted for mean bloo... | 18,809,715 |
Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. | Lis1 and Ndel1 are essential for animal development. They interact directly with one another and with cytoplasmic dynein. The developing brain is especially sensitive to reduced Lis1 or Ndel1 levels, as both proteins influence spindle orientation, neural cell fate decisions, and neuronal migration. We report here that ... | 18,809,722 |
Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements. | The single-pass transmembrane protein Ryk (atypical receptor related tyrosine kinase) functions as a Wnt receptor. However, Ryk's correlation with Wnt/Frizzled (Fz) signaling is poorly understood. Here, we report that Ryk regulates Xenopus laevis convergent extension (CE) movements via the beta-arrestin 2 (betaarr2)-de... | 18,809,723 |
Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium. | Formation of the primitive streak (PS) is the initial specification step that generates all the mesodermal and endodermal tissue lineages during early differentiation. Thus, a therapeutically compatible and efficient method for differentiation of the PS is crucial for regenerative medicine. In this study, we developed ... | 18,809,738 |
Elevated fluoride products enhance remineralization of advanced enamel lesions. | Caries prevention might benefit from the use of toothpastes containing over 1500 ppm F. With few clinical studies available, the aim of this pH-cycling study was to investigate the dose response between 0 and 5000 ppm F of de- and remineralization of advanced (> 150 microm) enamel lesions. Treatments included sodium... | 18,809,748 |
Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach. | Hematopoietic stem cells (HSCs) show pronounced heterogeneity in self-renewal and differentiation behavior, which is reflected in their repopulation kinetics. Here, a single-cell-based mathematical model of HSC organization is used to examine the basis of HSC heterogeneity. Our modeling results, which are based on the ... | 18,809,760 |
Homozygous deletion of HFE produces a phenotype similar to the HFE p.C282Y/p.C282Y genotype. | Hemochromatosis is predominantly associated with the HFE p.C282Y homozygous genotype, which is carried by approximately 1 person in 200 in Northern European populations. However, p.C282Y homozygosity is often characterized by incomplete penetrance. Here, we describe the case of a woman who had a major structural altera... | 18,809,761 |
Northcroft Memorial Lecture 2007. A century of progress: advances in orthodontics since the foundation of the British Society for the Study of Orthodontics. | The British Orthodontic Society invites outstanding contributors from the field of Orthodontics to give the guest lecture in memory of George Northcroft. In 2007 the guest lecturer was Professor Murray C. Meikle. The article that follows was presented as the Northcroft Memorial Lecture 2007 at the British Orthodontic C... | 18,809,781 |
A comparison of plaster, digital and reconstructed study model accuracy. | To evaluate the accuracy and reproducibility of a three-dimensional (3D) optical laser-scanning device to record the surface detail of plaster study models. To determine the accuracy of physical model replicas constructed from the 3D digital files. A method comparison study using 30 dental study models held in the Orth... | 18,809,782 |
Neighborhood income, health insurance, and prehospital delay for myocardial infarction: the atherosclerosis risk in communities study. | Outcomes following an acute myocardial infarction (AMI) are generally more favorable if prehospital delay time is minimized. We examined the association of neighborhood household income (nINC) and health insurance status with prehospital delay among a weighted sample of 9700 men and women with a validated, definite, or... | 18,809,814 |
Trade-offs in cervical cancer prevention: balancing benefits and risks. | New screening and vaccination technologies will provide women with more options for cervical cancer prevention. Because the risk of cervical cancer diminishes with effective routine screening, women may wish to consider additional attributes, such as the likelihood of false-positive results and diagnostic procedures fo... | 18,809,815 |
Cost-effectiveness of HIV monitoring strategies in resource-limited settings: a southern African analysis. | Although the number of infected persons receiving highly active antiretroviral therapy (HAART) in low- and middle-income countries has increased dramatically, optimal disease management is not well defined. We developed a model to compare the costs and benefits of 3 types of human immunodeficiency virus monitoring stra... | 18,809,819 |
Effects of social disruption on physical parameters, corticosterone concentrations, and immune system in two genetic lines of White Leghorn layers. | Farm management practices such as increasing group size and mixing of unfamiliar chickens may cause social disruption and affect bird well-being. To examine genetic-associated physical and physiological differences in response to social disruption, 2 strains of White Leghorn hens were used in the study [i.e., HGPS (lin... | 18,809,855 |
Effects of liquid aluminum chloride additions to poultry litter on broiler performance, ammonia emissions, soluble phosphorus, total volatile Fatty acids, and nitrogen contents of litter. | Recent studies have shown that the use of aluminum sulfate [alum, Al2(SO4)3.14H2O] and aluminum chloride (AlCl3) additions to animal manures are more effective than other chemicals in reducing ammonia (NH3) emissions and P solubility. Although the use of Al2(SO4)3.14H2O has been intensively used in the poultry industry... | 18,809,856 |
Effects of prelay 6/85-strain Mycoplasma gallisepticum inoculation alone or in conjunction with the inoculation of F-strain Mycoplasma gallisepticum during lay on the blood characteristics of commercial egg-laying hens. | The effects of 6/85-strain Mycoplasma gallisepticum (6/85MG) inoculation alone or in conjunction with F-strain M. gallisepticum (FMG) overlays and their timing on the blood characteristics of commercial egg-laying hens were investigated. Control birds received sham inoculations at 10 wk of age. Birds in a second treatm... | 18,809,862 |
Corn expressing an Escherichia coli-derived phytase gene: comparative evaluation study in broiler chicks. | The efficacy of corn expressing an Escherichia coli-derived gene (corn-based phytase; CBP) and an E. coli-derived microbial phytase (expressed in Pichia pastoris) sprayed onto a wheat carrier (Quantum) was comparatively evaluated in two 14-d broiler chicken studies. In experiment 1, a total of 288 seven-day-old male br... | 18,809,864 |
Factors affecting intestinal health in poultry. | The gastrointestinal (GI) tract has the most extensive exposed surface in the body and is constantly exposed to a wide variety of potentially harmful substances. The GI tract acts as a selective barrier between the tissues of the bird and its luminal environment. This barrier is composed of physical, chemical, immunolo... | 18,809,868 |
Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues. | Naturally acquired immune responses against human cancers often include CD8(+) T cells specific for the cancer testis antigen NY-ESO-1. Here, we studied T cell receptor (TCR) primary structure and function of 605 HLA-A*0201/NY-ESO-1(157-165)-specific CD8 T cell clones derived from five melanoma patients. We show that a... | 18,809,922 |
In vitro and in vivo validation of ligA and tarI as essential targets in Staphylococcus aureus. | A conditional expression system has been developed using the isopropyl-beta-d-thiogalactopyranoside (IPTG)-inducible Pspac promoter to validate essential genes of Staphylococcus aureus in vivo. The system has been applied to prove the essentiality of ligA and to evaluate the function of tarI, which was found to be esse... | 18,809,938 |
Sonographic differentiation of thyroid nodules with eggshell calcifications. | The purpose of this study was to assess the role of known suspicious sonographic findings and to find other additional sonographic findings to differentiate benign and malignant thyroid nodules with "eggshell" calcifications. Our Institutional Review Board approved this retrospective study, and informed consent was not... | 18,809,952 |
Biomechanical modelling of a direct vertebral translation instrumentation system: preliminary results. | Many new spine instrumentation concepts were introduced in recent years, like the incremental direct vertebral translation. The objective was to develop a biomechanical model in order to analyze the biomechanics of this instrumentation system. The patient-specific spine model was built using the 3D reconstruction based... | 18,810,013 |
Clinical and postural behaviour of scoliosis during daily brace weaning hours. | What happens to scoliosis when the brace is daily weaned is not described in the literature, even if this can have a significant clinical impact. Our aim was to evaluate the postural and clinical changes at brace weaning. We developed a pre-post trial in 10 adolescent idiopathic scoliosis female patients 12.6 years old... | 18,810,041 |
Congenital scoliosis - presentation of three severe cases treated conservatively. | In view of the very limited data about conservative treatment of patients with congenital scoliosis (CS) available, early surgery is suggested already in mild cases with formation failures in the first three years of life. It is common sense that patients with failures of segmentation will not benefit from conservative... | 18,810,043 |
Rolling to a lift. | A dynamic method to kneel and return to standing has been suggested. An amalgamation of principles and experiences has encouraged the advent of rolling to a lift. The method is applicable for patients with at least fair trunk control. J Orthop Sports Phys Ther 1982;4(2):118-119. | 18,810,102 |
Calculation of lsokinetic Rehabilitation Velocities for the Knee Extensors. | The aim of this study was to evaluate the validity of a method which provides for the calculation of the isokinetic speed of knee rehabilitation. The results indicated that, for the sampled population, the method produced validity coefficients (r = 0.98; r = 0.94) in the excellent range. Therefore, it was concluded tha... | 18,810,113 |
Trunk Testing Using a Prototype Cybex II lsokinetic Dynamometer Stabilization System. | This pilot study represents Cybex II isokinetic dynamometer trunk testing on 160 subjects (98 males, 62 females). A prototype apparatus which provides stabilization in the standing (functional) position was used in the testing. The testing protocols were performed first for trunk flexion and then trunk extension. The p... | 18,810,123 |
lontophoresis for Treatment of Shinsplints*. | It was hypothesized that shinsplints are the result of muscle inflammation induced by overuse; thus, as an inflammatory response, the application of an antiinflammatory medication to the involved muscles would eliminate the pain of shinsplints. The application of hydrocortisone by iontophoresis was effective in the eli... | 18,810,124 |
Academics versus Teachers: A Dilemma in Physical Therapy Education. | "These excerpts from the text of the Advisory Council on Physical Therapy Education, October 22, 1981, express the concerns of many clinical and research physical therapists about the current trends in physical therapy education. Although Dr. Rose makes a controversial assumption that effective educators need no formal... | 18,810,125 |
Physical therapy evaluation of the shoulder complex in athletes. | A systematic approach is presented for evaluating the shoulder complex in athletes. The evaluation is divided into two parts: the subjective and objective examinations. The evaluation will determine the severity of the injury, the irritability of injury, and the structural involvement, and provide objective data for de... | 18,810,134 |
Electromyographic Analysis of the Lower Extremity during Pedaling*. | EMG activity in the gluteus maximus, rectus femoris, biceps femoris, vastus lateralis, gastrocnemius, and anterior tibialis muscles was studied in six healthy male subjects. Each subject pedaled against changes in workload, pedaling rates, and different weight flywheels, with and without toe clips and from both sitting... | 18,810,152 |
A case study: application of ultrasound to determine a stress fracture of the fibula. | A female with a diagnosis of acute ankle sprain was evaluated for physical therapy treatment. Although radiological evidence was negative, the patient's history and symptoms suggested a stress fracture of the fibula. Application of ultrasound intensified the pain when directed to a specific point on the fibula. At a la... | 18,810,154 |
The straight-leg-raising test: a review*. | A positive unilateral straight-leg-raising sign is routinely interpreted as indicative of a "disc lesion. " A review of the literature was undertaken in an attempt to more clearly illustrate the mechanisms and results of the straight-leg-raising test. It was found that a positive straight-leg-raising test has minimal v... | 18,810,158 |
Sports medicine centers in the United States: the personnel, patients, and services. | Sports medicine in the United States is a rapidly expanding field. The movement of the public into organized and informal recreation and sports has stimulated the growth and sophistication of sports medicine. In the last 35 years, sports-related injuries have received unprecedented interest. Numerous sports medicine ce... | 18,810,170 |
On conversion reactions. | This article discusses the symptomatology of conversion reactions along with Freudian, behavioral, and holistic perspectives on their etiology. Factors influencing the incidence of conversion reactions and clues for identifying the disorder are presented.J Orthop Sports Phys Ther 1980;1(4):200-204. | 18,810,171 |
Dysfunction of the sacroiliac joint and its treatment*. | A very common but frequently overlooked cause of pain in the low back is a result of leaning forward without adequately supporting the anterior pelvis. This allows the innominates to rotate slightly downwards on the sacrum with fixation and an apparent increase in the length of the legs, which in turn irritates the sci... | 18,810,188 |
Translabyrinthine approach for vestibular schwannomas: operative technique. | For large vestibular schwannomas (VSs) for which removal is the primary therapy, the goals are complete tumor resection and maintenance of normal neurological function. The authors analyzed their results about facial nerve preservation, extent of resection and complications following resection of large VSs via a widene... | 18,810,201 |
Tissue changes after radiosurgery for vestibular schwannomas. | The specific effects of radiosurgery on brain tumor tissue are not well understood. We review several approaches that have been used to address this issue. Correlating the radiobiology of radiosurgery with the radioclinical outcome may help to understand these tissue changes. In vivo imaging investigations are usually ... | 18,810,206 |
Hearing preservation after complete microsurgical removal in vestibular schwannomas. | To evaluate and present the treatment strategy and hearing preservation in a recent series of vestibular schwannoma cases. A retrospective analysis of 200 patients operated consecutively over a 3 year period was performed. Patient records, operative reports, including data from the electrophysiological monitoring, foll... | 18,810,211 |
Economic evaluation alongside a phase II, multi-centre, randomised controlled trial of very early rehabilitation after stroke (AVERT). | The effectiveness and costs of very early rehabilitation after stroke are unknown. This study assessed the cost effectiveness of very early mobilisation in addition to standard care (VEM) compared with standard care alone (SC). Cost-effectiveness analysis alongside a phase II, multi-centre, randomised controlled trial ... | 18,810,233 |
Sex differences in stroke. | Increasing evidence suggests that sex differences exist in the etiology, presentation, treatment, and outcome from stroke. The reasons for these sex disparities are becoming increasingly explored, but large gaps still exist in our knowledge. Experimental studies over the past several years have demonstrated intrinsic s... | 18,810,232 |
Cerebellomedullary cerebrospinal fluid collection in the dog. | Analysis of cerebrospinal fluid (CSF) can be a valuable diagnostic tool. This column describes cerebellomedullary CSF collection in the dog. | 18,810,263 |
Metagenomic analysis of lysogeny in Tampa Bay: implications for prophage gene expression. | Phage integrase genes often play a role in the establishment of lysogeny in temperate phage by catalyzing the integration of the phage into one of the host's replicons. To investigate temperate phage gene expression, an induced viral metagenome from Tampa Bay was sequenced by 454/Pyrosequencing. The sequencing yielded ... | 18,810,270 |
Rapid and quantitative detection of the microbial spoilage in milk using Fourier transform infrared spectroscopy and chemometrics. | Microbiological safety plays a very significant part in the quality control of milk and dairy products worldwide. Current methods used in the detection and enumeration of spoilage bacteria in pasteurized milk in the dairy industry, although accurate and sensitive, are time-consuming. FT-IR spectroscopy is a metabolic f... | 18,810,291 |
Towards quantitatively reproducible substrates for SERS. | There is a need for a method to facilitate the development of novel, reproducible colloidal surface-enhanced Raman scattering (SERS) substrates to encourage the use of SERS in applied studies. In this study we show for the first time that by using suitably designed SERS experiments in conjunction with multivariate anal... | 18,810,294 |
Utilization of inpatient care before and after hip fracture: a population-based study. | Evaluation of hospitalizations in a 70+ population showed that hip fractures (HF) were associated with a significant increase in the utilization of inpatient care for a lengthy period. Hospital days attributable to several diagnostic classes still exceeded both prefracture and population levels in the second year after... | 18,810,302 |
The timing of ovulation with respect to sexual swelling detumescence in wild olive baboons. | Baboon researchers commonly use the timing of sexual swelling detumescence to infer the timing of ovulation. These estimates are then used for a variety of purposes, including the interpretation of male and female behaviour, assessment of likely paternity, and the calculation of gestation lengths. Although captive stud... | 18,810,314 |
Sporadic hemiplegic migraine: report of a case with clinical and radiological features. | A case of visual hallucination, headache and left hemiparesis is reported. The patient had a history of recurrent attacks of similar semiology for the previous 15 years. MRI brain revealed a cortical hyperintensity on T2W, FLAIR and diffusion weighted imaging (DWI) in the right cerebral hemisphere with a normal ADC (ap... | 18,810,316 |
Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy. | Purpose Glioblastoma Multiforme (GBM) is the most common and lethal primary brain tumor in adults. The goal of this study was to test the predictive value of MR parameters in relation to the survival of patients with newly diagnosed GBM who were scanned prior to receiving adjuvant radiation and chemotherapy. Methods Th... | 18,810,326 |
Chromosomal changes characterize head and neck cancer with poor prognosis. | It is well established that genetic alterations may be associated to prognosis in tumor patients. This study investigates chromosomal changes that predict the clinical outcome of head and neck squamous cell carcinoma (HNSCC) and correlate to characteristic clinicopathological parameters. We applied comparative genomic ... | 18,810,378 |
Medical simulation: a tool for recognition of and response to risk. | The use of simulation and team training has become an excellent tool to reduce errors in high-risk industry such as the commercial airlines and in the nuclear energy field. The health care industry has begun to use similar tools to improve the outcome of high-risk areas where events are relatively rare but where practi... | 18,810,414 |
The art of communication: strategies to improve patient and information flow : radiology perspective. | The art of communication involves understanding the needs of the person with whom one is interacting. The radiologist must be an expediter and a consultant. Face-to-face, eyeball-to-eyeball communication is almost always best. Nonverbal communication must be aligned with verbal principles. The radiologist must build tr... | 18,810,421 |
Extended MRI findings of intersection syndrome. | The symptoms and physical findings of intersection syndrome have been well described in the clinical medical literature. However, the magnetic resonance imaging (MRI) findings in patients with intersection syndrome of the forearm have only recently been described in a small number of patients. We review our experience ... | 18,810,435 |
[Molecular pathogenesis. Its importance in targeted therapy in colorectal cancer]. | Colorectal cancer has the second highest mortality of all cancers in Germany. In spite of advances in surgical and chemotherapeutic treatment, efficient new therapies need to be developed. In recent years, advances have been achieved by novel targeted therapies that are specifically directed against altered signaling p... | 18,810,440 |
Immunophenotyping without antibodies. New perspectives for lymphoma characterization. | Accurate classification of haematological malignancies is a prerequisite for their correct diagnosis, prognosis and therapy. Clear classification of lymphomas is often hindered by the limited number of available cell surface protein markers that are suitable for immunophenotyping. A systematic and quantitative analysis... | 18,810,443 |
Thymic enlargement in a patient with juvenile idiopathic arthritis during etanercept therapy. | Tumor necrosis factor (TNF) alpha inhibitors are effective in the treatment of inflammatory rheumatic diseases. Despite their effectiveness, anti-TNF drugs have some drawbacks such as severe adverse effects including infections and possibly lymphoproliferative disorders. In this report we described a case of juvenile i... | 18,810,448 |
Risk factors for nephrolithiasis in children. | The aim of this study is to evaluate the clinical outcome in children with urinary calculi, to detect risk factors for nephrolithiasis in childhood. This retrospective study comprised 62 pediatric nephrolithiasis patients who have come for routine follow-up visits between the dates of January 2002-August 2006 (48% girl... | 18,810,456 |
Primary Burkitt lymphoma presenting as a solitary rectal polyp in a child. | Non-Hodgkin lymphoma (NHL) accounts for approximately 60% of all lymphomas in children and adolescents. It represents 8-10% of all malignancies in children aged between 5 and 19 years. Primary rectal lymphoma in childhood is extremely rare. This report focuses on the importance of considering the possibility of maligna... | 18,810,465 |
Deposit of glass fragments during femtosecond laser penetrating keratoplasty. | To evaluate femtosecond laser interaction with the applanation lens during pre-programmed penetrating keratoplasty corneal cuts. Three different-shaped penetrating keratoplasty dissections were performed on edematous corneas from bank eyes using a clinical femtosecond laser system (Intralase FS60) with energies higher ... | 18,810,479 |
Epigenetic deregulation of the human Oct4 promoter in mouse cells. | To examine whether the epigenetic status of the human Oct4 promoter is similarly regulated in mouse cells, we engineered a human bacterial artificial chromosome to express green fluorescent protein under the control of the hOct4 promoter and stably integrated it into mouse embryonic stem cells (mESCs), NIH3T3, and 293T... | 18,810,488 |
Antiparasitic activity of biochanin A, an isolated isoflavone from fruits of Cassia fistula (Leguminosae). | The fractionation through bioguided antileishmanial activity of the dichloromethane extract of Cassia fistula fruits (Leguminosae) led to the isolation of the active isoflavone biochanin A, identified by spectroscopic methods. This compound showed 50% effective concentration (EC(50)) value of 18.96 microg/mL against pr... | 18,810,492 |
Artificial neural network models of relationships between Alternaria spores and meteorological factors in Szczecin (Poland). | Alternaria is an airborne fungal spore type known to trigger respiratory allergy symptoms in sensitive patients. Aiming to reduce the risk for allergic individuals, we constructed predictive models for the fungal spore circulation in Szczecin, Poland. Monthly forecasting models were developed for the airborne spore con... | 18,810,504 |
Candida albicans adhesion to composite resin materials. | The adhesion of Candida albicans to dental restorative materials in the human oral cavity may promote the occurrence of oral candidosis. This study aimed to compare the susceptibility of 14 commonly used composite resin materials (two compomers, one ormocer, one novel silorane, and ten conventional hybrid composites) t... | 18,810,508 |
The universal trend of amino acid gain-loss is caused by CpG hypermutability. | Understanding the cause of the changes in the amino acid composition of proteins is essential for understanding the evolution of protein functions. Since the early 1970s, it has been known that the frequency of some amino acids in protein sequences is increasing and that of others is decreasing. Recently, it was found ... | 18,810,523 |
Phylogenetic placement of pentatomid stink bug gut symbionts. | Insect bacterial symbionts are ubiquitous, however, only a few groups of host families have been well studied in relation to their associations with microbes. The determination of the phylogenetic relationships among bacteria associated with different species within an insect family can provide insights into the biolog... | 18,810,535 |
Superior mesenteric artery syndrome: diagnosis and treatment strategies. | Superior mesenteric artery (SMA) syndrome is an unusual cause of vomiting and weight loss resulting from the compression of the third part of the duodenum by the SMA. Various medical and psychiatric conditions may result in the initial rapid weight loss which causes narrowing of the aortomesenteric angle. The vomiting ... | 18,810,558 |
Pyogenic complications of Crohn's disease, evaluation, and management. | The principal by which treatment of pyogenic complications anorectal disease is guided should rely heavily on small procedure with medical management of rectal disease and limitation of proctectomy. Management of pyogenic complications of abdominal Crohn's by an elective approach after percutanea drainage of abscess an... | 18,810,560 |
Changes of the metabolism of the colon cancer cell line SW-480 under serum-free and serum-reduced growth conditions. | Serum of animal origin, like foetal calf serum (FCS), is used as a standard supplement for media to cultivate mammalian cells, mostly due to its growth-supporting properties. Unfortunately, animal serum has many disadvantages like the risk of contamination, high costs, fluctuations within the composition of different b... | 18,810,564 |
In vitro study of haematoporphyrin monomethyl ether-mediated sonodynamic effects on C6 glioma cells. | To study the cytotoxicity induced by haematoporphyrin monomethyl ether (HMME)-mediated sonodynamic therapy (SDT) on C6 glioma cells. The potent photosensitizer HMME was used as the sensitizer. Rat C6 glioma cells were incubated with HMME (10 microg/mL) in the dark for 2 h and then subjected to ultrasound treatment at 1... | 18,810,596 |
Conservative treatment of ruptured vertebrobasilar dissecting aneurysm. | Ruptured vertebrobasilar dissecting aneurysm is usually treated surgically because rebleeding negatively affects outcome. However, the risk of rebleeding decreases markedly once several hours have passed from the initial bleeding. Moreover, surgery-related complications are not rare. We describe seven patients with rup... | 18,810,598 |
The use of the MacCAT-CA with adolescents: an item response theory investigation of age-related measurement bias. | Despite the application of the MacCAT-CA to juveniles, questions been raised regarding the appropriateness of this tool for adolescents. The current study tested for age-related measurement bias using data from the MacArthur Juvenile Adjudicative Competence Study (n = 1393). Five of the MacCAT-CA items showed age-relat... | 18,810,614 |
Comparison of atrial fibrillation inducibility by electrical stimulation of either the extrinsic or the intrinsic autonomic nervous systems. | To study the effects of bilateral vagosympathetic nerve stimulation (VNS) and ganglionated plexi stimulation (GPS) on atrial refractoriness and inducibility of atrial fibrillation (AF). Studies were performed in fourteen adult mongrel dogs anesthetized with Na-pentobarbital, 30 mg/kg. VNS was achieved by insertion of w... | 18,810,624 |
Dissecting "gaydar": accuracy and the role of masculinity-femininity. | "Gaydar" is the ability to distinguish homosexual and heterosexual people using indirect cues. We investigated the accuracy of gaydar and the nature of "gaydar signals" conveying information about sexual orientation. Homosexual people tend to be more sex atypical than heterosexual people in some behaviors, feelings, an... | 18,810,629 |
Vesico-vaginal fistula: report of 220 cases. | To present the major causes, diagnosis, indications, and basic principles of surgical treatment of vesico-vaginal fistulas (VVF). From 1978 to 2004, 235 surgical procedures in 220 women with vesico-vaginal fistulas were performed at the Clinical Center of Serbia, Urological Clinic, due to primary or recurrent VVF. Ther... | 18,810,652 |
Symbiosis between microorganisms from kombucha and kefir: Potential significance to the enhancement of kombucha function. | Gluconacetobacter sp. A4 (G. sp. A4), which had strong ability to produce d-saccharic acid 1, 4 lactone (DSL), was the key functional bacteria isolated from the kombucha preserved. This paper investigated the interaction between G. sp. A4 and ten different strains of lactic acid bacteria (LAB) obtained from kefir. The ... | 18,810,658 |
Metaanalysis of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage. | Tirilazad is a non-glucocorticoid, 21-aminosteriod that inhibits lipid peroxidation. It had neuroprotective effects in experimental ischemic stroke and reduced angiographic vasospasm after experimental subarachnoid hemorrhage (SAH). Five randomized clinical trials of tirilazad were conducted in patients with SAH. We pe... | 18,810,661 |
Palliative surgical bypass for pancreatic and peri-ampullary cancers. | The optimal method of palliation for patients with unresectable pancreatic and peri-ampullary cancer (PAC) is controversial with surgical bypass or endoscopic stenting, each having advantages and disadvantages. We analysed short term outcomes and survival for all patients undergoing surgical palliative bypass procedure... | 18,810,668 |
Probiotic Escherichia coli Nissle 1917 (EcN) for successful remission maintenance of ulcerative colitis in children and adolescents: an open-label pilot study. | Since about 20 % of patients with ulcerative colitis (UC) are children and adolescents there is a need for therapeutic options custom-tailored to the children's needs. E. coli Nissle 1917 (EcN) as an evidence-based probiotic alternative to mesalazine (5-ASA) in adult UC remission maintenance is a promising agent for su... | 18,810,672 |
[An unusual cause of severe abdominal pain]. | A 33-year-old previously healthy man was admitted to the hospital with a 6-day history of diffuse abdominal pain and constipation. He was afebrile, looked unwell with a pale skin and displayed an elevated blood pressure. He had no peritoneal sign, and bowel sounds were normal. Blood tests were remarkable for a hematocr... | 18,810,673 |
Photophysical and duplex-DNA-binding properties of distamycin dimers based on 4,4'- and 2,2'-dialkoxyazobenzenes as the core. | Distamycin-based tetrapeptide (1) was covalently tethered to both ends of the central dihydroxyazobenzene moiety at either the 2,2' or 4,4' positions. This afforded two isomeric, distamycin-azobenzene-distamycin systems, 2 (para) and 3 (ortho), both of them being photoisomerizable. Illumination of these conjugates in s... | 18,810,740 |
Spontaneous resolution of chiral polyoxometalate-based compounds consisting of 3D chiral inorganic skeletons assembled from different helical units. | Four enantiomerically pure 3D chiral POM-based compounds, [Ni(2)(bbi)(2)(H(2)O)(4)V(4)O(12)]2 H(2)O (1 a and 1 b) and [Co(bbi)(H(2)O)V(2)O(6)] (2 a and 2 b) (bbi=1,1'-(1,4-butanediyl)bisimidazole) based on the achiral ligand, different vanadate chains, and different metal centers have been synthesized by hydrothermal m... | 18,810,744 |
Crohnology: a tale of time and times and inflammatory bowel diseases. | Time, times and timing are key words in inflammatory bowel diseases (IBD). The leitmotif of this issue of World Journal of Gastroenterology is time. We have asked experts to review on the epidemiology of these diseases over time, the changes in innate immunity that could be present in the first time, and then the timin... | 18,810,763 |
Treatment of severe steroid refractory ulcerative colitis. | Although systemic steroids are highly efficacious in ulcerative colitis (UC), failure to respond to steroids still poses an important challenge to the surgeon and physician alike. Even if the life time risk of a fulminant UC flare is only 20%, this condition is potentially life threatening and should be managed in hosp... | 18,810,767 |
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