title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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[The mortality of the able-bodied population in the Irkutsk oblast]. | The comprehensive evaluation of the irrevocable demographic losses among the able-bodied population in Irkutsk oblast. The quantitative structural analysis was implemented as applied to the characteristics of mortality of this population contingent. The peculiarities of formation of the vital potential of the economica... | 18,810,790 |
Uncontrolled asthma means missed work and school, emergency department visits for many Californians. | In 2005, three million Californians reported that they had current asthma. Despite advances in therapy, asthma remains a disease that is not optimally controlled in many Californians. Inadequately controlled asthma can result in missed work and school and emergency department visits. Asthma was responsible for an estim... | 18,810,806 |
Characteristics of enterotoxin H-producing Staphylococcus aureus isolated from clinical cases and properties of the enterotoxin productivity. | Staphylococcal enterotoxin H (SEH) is predicted to be involved in staphylococcal food poisoning. To characterize SEH-producing Staphylococcus aureus isolates from staphylococcal food poisoning cases in Japan, we investigated the relationship between SEH production and coagulase serotype, which is an epidemiological mar... | 18,810,869 |
Birthweight and gestational age by ethnic group, England and Wales 2005: introducing new data on births. | Low birthweight babies and babies born preterm are at increased risk of morbidity and mortality in the first year of life, as well as in the longer-term. Since information on ethnic group is not recorded at birth registration in England and Wales, it has not been possible to produce routine statistics on birthweight or... | 18,810,886 |
Maori women's views on smoking cessation initiatives. | Smoking is particularly prevalent among Maori women over the age of 15 years and remains a concern despite anti-smoking campaigns. This raises questions about the effectiveness of current smoking cessation initiatives as mainstream tobacco control programmes have not benefited Maori to the same extent as non-Maori. Lim... | 18,810,902 |
Ethical decision-making for multiple prescription dentistry. | Technology provides a selection of treatment choices for dental problems. Dental ethics must be applied to the development of a treatment plan and the selection of methods. Treatment options should consider the patient's circumstances and desires as well as the dentist's decision as it relates to best practices in dent... | 18,810,913 |
An analysis on flavonoids contents in Mao Luang fruits of fifteen cultivars (Antidesma bunius), grown in northeast Thailand. | This investigation was carried out at the Department of Biotechnology, Faculty of Technology, Mahasarakham University, Mahasarakham Province, Northeast Thailand. The study aimed to analyze flavonoids contents in ripe fruits of fifteen Mao Luang cultivars (Antidesma bunius) harvested from dipterocarp forest of the mount... | 18,810,968 |
Plant regeneration and floral bud formation from intact floral parts of African violet (Saintpaulia ionantha H. Wendl.) cultured in vitro. | Intact immature flower buds of African violet (Saintpaulia ionantha H. Wendl.) were used as explant sources for in vitro studies. The effect of exogenous hormones, NAA and BAP on the indirect organogenesis of this species was observed. Callus was formed on the cut end (base) of pedicels of floral buds where they were i... | 18,810,979 |
Biotransformation of glabratephrin, a rare type of isoprenylated flavonoids, by Aspergillus niger. | Microbial transformation of glabratephrin, the major isolated compound from Tephrosia purpurea, afforded pseudosemiglabrin. The formation of the transformed compound seems to be performed via ring opening-closure of a five-membered ring causing transformation from a spiro into a fused system. The structure of the trans... | 18,811,002 |
Microtitre plate assay for biofilm formation, production and utilization of hydroxybiphenyl by Rhodococcus sp. isolated from gasoline-contaminated soil. | Gasoline-contaminated soil from Isfahan, Iran was selected to isolate a bacterium capable of desulfurizing dibenzothiophene (DBT). The isolated strain was named R1 and identified as Rhodococcus erythropolis through biochemical tests as well as sequencing of 16S rRNA gene. This strain could efficiently produce 2-hydroxy... | 18,811,008 |
Decreased DNA repair capacity of UV-irradiated cells following interferon treatment. | The aim of this study was to examine the effect of interferons (IFNs) on the recovery of UV-damaged cells by means of measuring cell viability rates. The influence of the recombinant human interferons IFN-alpha, IFN-beta and IFN-gamma on the repair capacity of the UV-irradiated human cell lines WISH and HeLa was studie... | 18,811,009 |
Idiopathic gingival fibromatosis: a review of the literature and a case report. | Gingival fibromatosis is characterized by localized or generalized fibrous enlargement of the gingivae, mainly around permanent teeth. Gingival fibromatosis affects only the masticatory mucosa and does not extend beyond the muco-gingival junction. This article describes an unusual case of idiopathic gingival fibromatos... | 18,811,080 |
A comparison of two liner materials for use in the ferric sulfate pulpotomy. | The aim of this study is to compare the success rate obtained when applying either a calcium hydroxide (Dycal) base or a zinc oxide-eugenol (Kalzinol) base following the traditional ferric sulfate pulpotomy. Patients were either treated in the chair or under general anaesthesia. All teeth had to have radiographic evide... | 18,811,097 |
Empirical support for a fissure sealant placement timeframe protocol for black South Africans. | It is recommended that fissure sealants should be placed within four years after eruption. Due to considerable variations in the eruption times of molar teeth, this recommendation is of limited value from a public health perspective. This study, therefore, sought to provide empirical support for a public health fissure... | 18,811,098 |
Spectroscopic and computational studies of (mu-oxo)(mu-1,2-peroxo)diiron(III) complexes of relevance to nonheme diiron oxygenase intermediates. | With the goal of gaining insight into the structures of peroxo intermediates observed for oxygen-activating nonheme diiron enzymes, a series of metastable synthetic diiron(III)-peroxo complexes with [Fe(III)(2)(mu-O)(mu-1,2-O(2))] cores has been characterized by X-ray absorption and resonance Raman spectroscopies, EXAF... | 18,811,130 |
Sn(x)Pt4Sn(y)Sb(12-y): a skutterudite with covalently bonded filler. | A new phase, Sn(x)Pt4Sb(12-y)Sn(y), has been prepared from the elements. It exhibits a wide range of homogeneity with 0.3(2) < or = x < or = 1.0(2) and 4.2(2) < or = y < or = 7.0(2). The crystal structure and the composition were established by single-crystal and powder X-ray diffraction as well as waveleng... | 18,811,146 |
DNA-binding and physical studies of Pt(4'-NR2-trpy)CN+ systems (trpy = 2,2':6',2''-terpyridine). | This paper focuses on DNA-binding interactions exhibited by Pt(dma-T)CN(+), where dma-T denotes 4'-dimethylamino-2,2':6',2''-terpyridine, and includes complementary studies of the corresponding pyrr-T complex, where pyrr-T denotes 4'-(N-pyrrolidinyl)-2,2':6',2''-terpyridine. The chromophores are useful for understandin... | 18,811,150 |
Palladium-catalyzed amination of aryl and heteroaryl tosylates at room temperature. | Mild palladium-catalyzed aminations of aryl tosylates and the first aminations of heteroaryl tosylates are described. In the presence of the combination of L2Pd(0) (L = P(o-tol)3) and the hindered Josiphos ligand CyPF-t-Bu, a variety of primary alkylamines and arylamines react with both aryl and heteroaryl tosylates at... | 18,811,161 |
Emission of volatile chemicals from flowering dogwood (cornus Florida L.) flowers. | Reproduction of flowering dogwood trees occurs via obligate out-crossing, and U.S. native bees have been suggested to be primary pollinators of this ecologically and economically important deciduous tree. Whether floral volatiles play a role in reproduction of the dogwood remains unclear. Objectives of this study were ... | 18,811,168 |
Origins of the double asymmetric induction on proline-catalyzed aldol reactions. | Computational studies to elucidate the origin of the double asymmetric induction on proline-catalyzed aldol reaction have been performed using HF/6-31G(d) calculations. The computed transition structures explain the experimental data obtained. | 18,811,197 |
Alkaloids from the twigs of Daphniphyllum calycinum. | Twelve new alkaloids, caldaphnidines G-R (1-12), along with 24 known ones, were isolated from the twigs of Daphniphyllum calycinum. Their structures were elucidated by spectroscopic methods, especially two-dimensional NMR techniques. | 18,811,206 |
TAC-scaffolded tripeptides as artificial hydrolytic receptors: a combinatorial approach toward esterase mimics. | In this report, we present the first library of tripodal synthetic receptor molecules containing three different, temporarily N-terminal protected peptide arms capable of performing hydrolytic reactions. To construct this library, the orthogonally protected triazacyclophane (TAC)-scaffold was used in the preparation of... | 18,811,207 |
One-by-one coupling of single defect centers in nanodiamonds to high-Q modes of an optical microresonator. | In this letter, we present the on-demand coupling of single NV(-) defect centers in nanodiamonds to a polystyrene microspherical resonator. From an ensemble on a coverslip, we select single nanodiamonds containing a single defect proven by a pronounced antibunching dip. With the help of a scanning near-field probe, we ... | 18,811,213 |
Synthesis of hybrid multicomponent disklike nanoparticles. | This manuscript describes the synthesis of a new generation of multicomponent disklike nanoparticles. In this work, we present for the first time, through the template-based sequential electrochemical deposition of metal/semiconductor/polymer segments, an innovative and effective method for preparing a wide range of me... | 18,811,214 |
Single- and two-species tests to study effects of the anthelmintics ivermectin and morantel and the coccidiostatic monensin on soil invertebrates. | Soil invertebrates in arable land are potentially exposed to veterinary medicines excreted by husbandry. The toxicity of three widely used pharmaceuticals was therefore investigated with the use of common soil invertebrates exposed in the laboratory in single- or two-species test system. The anthelmintic morantel did n... | 18,811,226 |
Autophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it. | Mycobacterium tuberculosis is a facultative intracellular pathogen that parasitizes host macrophages where it persists in immature phagosomes by avoiding their maturation into phagolysosomes. The mechanisms of how M. tuberculosis inhibits phagolysosome biogenesis have been researched in detail and the maturation block ... | 18,811,236 |
Genetic algorithms with memory- and elitism-based immigrants in dynamic environments. | In recent years the genetic algorithm community has shown a growing interest in studying dynamic optimization problems. Several approaches have been devised. The random immigrants and memory schemes are two major ones. The random immigrants scheme addresses dynamic environments by maintaining the population diversity w... | 18,811,247 |
An empirically based model for latitudinal gradient in vole population dynamics. | Vole dynamics in northern Europe exhibit a well-defined geographical gradient, with oscillatory populations being confined to high latitudes. It has been proposed that oscillations in northern vole populations are driven by their interaction with specialist predators (weasels), while the more southern rodent population... | 18,811,252 |
Does food web complexity eliminate trophic-level dynamics? | Investigators are always divided into those who are looking for rules and those who are looking for exceptions. (Hackett 1937, p. 106). | 18,811,260 |
Mutualism among safe, selfish sentinels: a dynamic game. | Sentinels are group members that watch from prominent positions. Sentinel interchanges often appear orderly, and groups with sentinels rarely have zero or many sentinels. A dynamic game was constructed to examine if these observations about sentinels could be based on selfish actions by individual group members. In thi... | 18,811,295 |
Ecological biogeography of southern ocean islands: species-area relationships, human impacts, and conservation. | Previous studies have concluded that southern ocean islands are anomalous because past glacial extent and current temperature apparently explain most variance in their species richness. Here, the relationships between physical variables and species richness of vascular plants, insects, land and seabirds, and mammals we... | 18,811,364 |
Sexual dimorphism in immune defense. | Sex differences in parasitism are common and may depend on sex differences in intensity of sexual competition, immunosuppression, or exposure to parasites. We used a large data set on the mass of two immune defense organs in birds (the bursa of Fabricius and the spleen) to test for consistent sex differences in immune ... | 18,811,367 |
Predator-mediated plasticity in morphology, life history, and behavior of Daphnia: the uncoupling of responses. | We studied the way 12 traits responded to fish kairomones in a set of 16 Daphnia magna clones derived from four different habitats-two where daphnids co-occur with fish and two without fish. These clones differed widely in their response to predator kairomones, with none of the clones showing a significant response in ... | 18,811,388 |
Competition in a group of equal foragers. | Using techniques from renewal process theory, we build a stochastic model for gain accumulation in a group of equal competitors foraging in a patchy environment. The model for gain of the individuals is based on the waiting times between subsequent prey encounters by the group. These waiting times depend on the number ... | 18,811,402 |
Sexual conflict and the energetic costs of mating and mate choice in water striders. | Analyses of intersexual conflicts of interest over courtship, mating, or mate guarding require an understanding of the physiological costs of sexual interaction. Repeated respirometric measures of energetic expenditure were taken on female Aquarius remigis while unladen and while carrying a mating male, a small metal w... | 18,811,423 |
Reconciling classical and individual-based approaches in theoretical population ecology: a protocol for extracting population parameters from individual-based models. | The two main approaches in theoretical population ecology-the classical approach using differential equations and the approach using individual-based modeling-seem to be incompatible. Linked to these two approaches are two different timescales: population dynamics and behavior or physiology. Thus, the question of the r... | 18,811,431 |
Within-brood competition and the optimal partitioning of parental investment. | In this article, we introduce a simple within-brood competitive growth model that maximizes parental fitness in unpredictable food conditions in species that exhibit parental care, progressive provisioning, and an initial brood overproduction. We argue that competition between siblings may provide a proximate mechanism... | 18,811,449 |
Chaos in the Pacific's coral reef bleaching cycle. | There is no simple explanation for the unusual increase in coral reef bleaching events that have been occurring on a global scale over the last 2 decades. Recent studies focusing on this problem reveal that mass bleaching events have a strong periodic component, arising every 3-4 yr in step with the El Niño climatic ph... | 18,811,451 |
A new look at relationships between size at maturity and asymptotic size. | Comparative studies have revealed positive correlations between size at maturity and asymptotic size in several taxa with asymptotic growth after maturity. Using a simple growth model, we show that positive correlations between size at maturity and asymptotic size are predicted for different individuals in the same spe... | 18,811,453 |
Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity. | Members of the ADAM (a disintegrin and metalloproteinase) family of proteins possess a multidomain architecture which permits functionalities as adhesion molecules, signalling intermediates and proteolytic enzymes. ADAM8 is found on immune cells and is induced by multiple pro-inflammatory stimuli suggesting a role in i... | 18,811,590 |
Similar expression of through-and-through fluid movement along orthograde apical plugs of MTA Bio and white Portland cement. | To compare the sealing ability of four hydraulic cements when used as an apical plug in teeth with wide-open apices. A sample of 70 maxillary central incisors were divided into four groups (n = 15) and a further 10 teeth served as controls. An artificial open apex was created in the teeth using Gates Glidden drills num... | 18,811,597 |
The IMPROVE study--a multinational, observational study in type 2 diabetes: baseline characteristics from eight national cohorts. | The IMPROVE study is a multinational, open-label, non-randomised, 26-week observational study assessing the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) treatment in type 2 diabetes in routine clinical practice. The principal aims of this report were to characterise the baseline population and phys... | 18,811,598 |
Risk factors for fracture following a fall among older people in residential care facilities in Australia. | To investigate which factors best predict whether a fall will result in a fracture. Prospective cohort. Residential care facilities. One thousand three hundred forty-two older men and women (mean age 86.0) who had a fall. Clinical risk factors and bone fragility by calcaneus broadband ultrasound attenuation (BUA) were ... | 18,811,606 |
A manual of guidelines to score the modified cumulative illness rating scale and its validation in acute hospitalized elderly patients. | To update previous guidelines to score the Cumulative Illness Rating Scale (CIRS) and test their usefulness in hospitalized elderly patients. The CIRS was scored retrospectively in a cohort of elderly patients followed for 18 months. An acute internal medicine ward in an academic tertiary care hospital. Three hundred e... | 18,811,613 |
A new PTGDR promoter polymorphism in a population of children with asthma. | Recently, functional genetic variants of the PTGDR gene have been associated with asthma. The objective of this work was to study polymorphisms of the promoter region of PTGDR and their haplotype and diplotype combinations in a Spanish population of children with asthma. In this study, 200 Caucasian individuals were in... | 18,811,623 |
Vibrio cholerae non-O1 infection in cirrhotics: case report and literature review. | Vibrio species are ubiquitous in the marine environment and can cause severe infections in cirrhotic patients. Patients with liver disease should be warned about the potential dangers of consuming raw or undercooked seafood, and avoiding exposure of wounds to seawater. We report a case of severe sepsis from Vibrio chol... | 18,811,633 |
The consent and prescription compliance (COPRECO) study: does obtaining consent in the emergency department affect study results in a telephone follow-up study of medication compliance? | The objectives were to determine whether mandated research requirements for consent in the emergency department (ED) falsely distorts the results of a survey of patient-reported compliance with ED prescriptions and, in addition, to ascertain the level of patient compliance to medication instructions and find out the de... | 18,811,636 |
Role of menaquinone biosynthesis genes in selenate reduction by Enterobacter cloacae SLD1a-1 and Escherichia coli K12. | In this study, we investigated the role of menaquinone biosynthesis genes in selenate reduction by Enterobacter cloacae SLD1a-1 and Escherichia coli K12. A mini-Tn5 transposon mutant of E. cloacae SLD1a-1, designated as 4E6, was isolated that had lost the ability to reduce Se(VI) to Se(0). Genetic analysis of mutant st... | 18,811,645 |
Nice natives and mean migrants: the evolution of dispersal-dependent social behaviour in viscous populations. | There has been much interest in the evolution of social behaviour in viscous populations. While low dispersal increases the relatedness of neighbours, which tends to promote the evolution of indiscriminate helping behaviour, it can also increase competition between neighbours, which tends to inhibit the evolution of he... | 18,811,663 |
Prevention of shedding and re-shedding of Toxoplasma gondii oocysts in experimentally infected cats treated with oral Clindamycin: a preliminary study. | This work aimed to evaluate the effects of preventive oral Clindamycin in cats infected with Toxoplasma gondii. Twelve short hair cats were divided into two groups (group 1 and group 2). No titres of T. gondii antibodies were detected in these cats before the experiment. The animals from group 1 were infected with tiss... | 18,811,675 |
Mechanism of tyrosinase inhibition by deoxyArbutin and its second-generation derivatives. | Disorders, such as age spots, melasma and hyperpigmentation at sites of actinic damage, emanate from the augmentation of an increased amount of epidermal melanin. The ineptness of current therapies in treating these conditions, as well as high cytotoxicity, mutagenicity, poor skin penetration and low stability of skin-... | 18,811,684 |
Identification of a previously unrecognized microdeletion syndrome of 16q11.2q12.2. | We report the identification of microdeletions of 16q11.2q12.2 by microarray-based comparative genomic hybridization (aCGH) in two individuals. The clinical features of these two individuals include hypotonia, gastroesophageal reflux, ear anomalies, and toe deformities. Other features include developmental delay, menta... | 18,811,697 |
Motor coordination difficulties and physical fitness of extremely-low-birthweight children. | Motor coordination difficulties and poor fitness exist in the extremely low birthweight (ELBW) population. This study investigated the relative impact of motor coordination on the fitness of ELBW children aged 11 to 13 years. One hundred and nine children were recruited to the study: 54 ELBW participants (mean age at a... | 18,811,704 |
Waiting for child developmental and rehabilitation services: an overview of issues and needs. | Concern about the length of time that children, young people, and families may have to wait to access assessment, diagnostic, interventional, therapeutic, and supportive child developmental and rehabilitation (CDR) services is widespread, but adequate data collection and research on this issue remain limited. We review... | 18,811,706 |
Identification and management of polyvascular disease in patients with noncardioembolic ischaemic stroke. | Recent registry results have shown that polyvascular disease (PolyVD), usually manifested as coronary heart disease or peripheral arterial disease (PAD), is a marker of increased morbidity and mortality in patients with noncardioembolic ischaemic stroke, but is often inadequately assessed. This Personal View Paper advo... | 18,811,739 |
Diagnostic accuracy of CT angiography in acute gastrointestinal bleeding. | The aim of the study was to carry out a systematic review determining the accuracy of CT angiography in the diagnosis of acute gastrointestinal bleeding. A search of published work in Medline and manual searching of reference lists of articles was conducted. Studies were included if they compared CT angiography to a re... | 18,811,756 |
Basal cell carcinoma of the nose: an Australian and New Zealand radiation oncology patterns-of-practice study. | Patients with a basal cell carcinoma (BCC) of the nose may be recommended radiotherapy (RT) with a wide variation in techniques and prescribed dose fractionation schedules between clinicians. The aim of this study was to ascertain variability in the patterns of practice among Australian and New Zealand radiation oncolo... | 18,811,764 |
The parental experience of pregnancy after perinatal loss. | To review the research literature on the parental experience of pregnancy, primarily maternal, subsequent to perinatal loss. Computerized searches on CINAHL and PubMed databases. Articles from indexed journals relevant to the objective were reviewed from January 1997 to December 2007. Only research-based studies in Eng... | 18,811,772 |
Percent body fat, skinfold thickness or body mass index for defining obesity or overweight, as a risk factor for asthma in schoolchildren: which one to use in epidemiological studies? | None of the epidemiological studies indicating that obesity is a risk factor for asthma in schoolchildren have used the percent body fat (PBF) to define obesity. The present study compares the definition of obesity using body mass index (BMI), PBF and the raw sum of the thickness of four skinfolds (SFT) to evaluate thi... | 18,811,794 |
Ventricular arrhythmias after left ventricular assist device implantation. | Left ventricular assist devices (LVADs) have been used as a bridge to cardiac transplantation and as destination therapy in patients with advanced heart failure. The period after LVAD support is associated with ventricular arrhythmias (VAs) despite ventricular unloading and such VAs can have a detrimental effect on sur... | 18,811,803 |
Focal AF-ablation after pulmonary vein isolation in a patient with hypertrophic cardiomyopathy using cryothermal energy. | A 42-year-old man, with a history of hypertrophic cardiomyopathy (HCM), an electrocardiogram pattern of ventricular preexcitation typical for mutations in the PRKAG2 gene, and highly symptomatic paroxysmal drug-resistant atrial fibrillation (AF), underwent successful circumferential isolation of his pulmonary veins usi... | 18,811,822 |
Paracetamol (Acetaminophen): mechanisms of action. | Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors. Prostaglandin H(2) synthetase (PG... | 18,811,827 |
Non-invasive diagnostic evaluation of phototherapeutic effects of red light phototherapy of acne vulgaris. | During the past few years, various phototherapeutic protocols with full-spectrum visible light or selected wavebands have been investigated in the treatment of acne vulgaris with variable results. Fifteen women suffering from moderate acne vulgaris of the face were exposed to 20 J/cm(2) of broad-band red (lambda: 600-7... | 18,811,865 |
Evaluation of sunscreen products using a reconstructed skin model exposed to simulated daily ultraviolet radiation: relevance of filtration profile and SPF value for daily photoprotection. | The recent definition of a standard daily ultraviolet radiation (DUVR) has allowed us to reproduce non-zenithal sun exposure conditions. Exposure to simulated DUVR induces biological damage in human skin, suggesting the need for an appropriate photoprotection. Sunscreen products were evaluated using human reconstructed... | 18,811,866 |
Bronchodilator reversibility, airway eosinophilia and anti-inflammatory effects of inhaled fluticasone in COPD are not related. | Bronchodilator reversibility (BDR) is common in smoking-related COPD, but the airway pathology underlying this has not been described. In particular, it is not known whether BDR is associated with underlying airway eosinophilia and whether BDR is predictive of a better response to inhaled corticosteroid (ICS) treatment... | 18,811,878 |
Acylated ghrelin level in patients with OSA before and after nasal CPAP treatment. | Patients with newly diagnosed OSA have been reported to have recent weight gain prior to diagnosis. Ghrelin stimulates food intake and increases weight gain. Plasma ghrelin is decreased in obese and increased in lean individuals. Of the two circulating forms of ghrelin, acylated and unacylated, the former is thought to... | 18,811,879 |
Limited role for outpatient parenteral antibiotic therapy for community-acquired pneumonia. | This study examined the potential utility of outpatient parenteral antibiotic therapy (OPAT) as a means of reducing the excessive number of patients hospitalized with low-risk community-acquired pneumonia (CAP). A prospective feasibility study was conducted, in which a selection algorithm was applied to a cohort of pat... | 18,811,888 |
Evaluation of the risks of shedding Salmonellae and other potential pathogens by therapy dogs fed raw diets in Ontario and Alberta. | Dogs that participate in animal-assisted interventions (AAIs), often called 'therapy dogs', commonly interact with humans whose immune systems are not functioning optimally. The advisability of feeding raw meat (including poultry) to these animals remains a highly contentious issue, in spite of increasing evidence that... | 18,811,908 |
Reversal of benign prostate hyperplasia by selective occlusion of impaired venous drainage in the male reproductive system: novel mechanism, new treatment. | The prostate is an androgen-regulated exocrine gland producing over 30% of the noncellular components of the semen and promoting optimal conditions for survival and motility of sperm in the vagina. Benign prostate hyperplasia (BPH) is the most common benign neoplasm in men. Its aetiology is not clear, and therefore, cu... | 18,811,916 |
Decline of plasma 5alpha-dihydrotestosterone (DHT) levels upon testosterone administration to elderly men with subnormal plasma testosterone and high DHT levels. | The study was performed to measure the impact of testosterone (T) administration on circulating levels of 5alpha-dihydrotestosterone (DHT). Group 1 (32 men; mean age 61 years; mean T 6.9 +/- 1.9 nmol l(-1)) were treated for 15 months with long-acting T undecanoate. Group 2 (23 men, mean age 60 years, mean T 7.6 +/- 2.0... | 18,811,920 |
Effect of repeated sequential ejaculation on sperm DNA integrity in subfertile males with asthenozoospermia. | The aim of this work was to study the possible beneficial effect of repeated sequential ejaculation on sperm DNA integrity in subfertile males and its possible implementation in assisted reproduction. The study included 20 infertile males with idiopathic asthenozoospermia or oligoasthenozoospermia. They underwent detai... | 18,811,922 |
SSMap: a new UniProt-PDB mapping resource for the curation of structural-related information in the UniProt/Swiss-Prot Knowledgebase. | Sequences and structures provide valuable complementary information on protein features and functions. However, it is not always straightforward for users to gather information concurrently from the sequence and structure levels. The UniProt knowledgebase (UniProtKB) strives to help users on this undertaking by providi... | 18,811,932 |
A comparison of EQ-5D index scores using the UK, US, and Japan preference weights in a Thai sample with type 2 diabetes. | Data are scarce on the comparison of EQ-5D index scores using the UK, US, and Japan preference weights in other populations. This study was aimed to examine the differences and agreements between these three weights, psychometric properties including test-retest reliability, convergent and known-groups validity, and th... | 18,811,935 |
Passive administration of monoclonal antibodies to anthrolysin O prolong survival in mice lethally infected with Bacillus anthracis. | Bacillus anthracis has two major virulence factors: a tripartite toxin that produces lethal and edema toxins and a polyglutamic acid capsule. A recent report suggested that a toxin belonging to the cholesterol dependent cytolysin (CDC) family, anthrolysin O (ALO) was a new virulence factor for B. anthracis but subseque... | 18,811,967 |
The purpose, composition, and function of an institutional review board: balancing priorities. | The institutional review board (IRB) is one part of the research enterprise designated to protect human subjects. At times the IRB can feel like an oppressive oversight body bound by regulations and designed to inhibit research. However, in reality the IRB was an attempt by the federal government to streamline a variet... | 18,811,996 |
Induction of immunity in sheep to Fasciola hepatica with mimotopes of cathepsin L selected from a phage display library. | An M13 phage random 12-mers peptide library was used to screen cathepsin L mimotopes of Fasciola hepatica and to evaluate their immunogenicity in sheep. Seven clones showed positive reactivity to a rabbit anti-cathepsin L1/L2 antiserum in ELISA, and their amino acid sequences deduced by DNA sequencing were tentatively ... | 18,812,010 |
Suppressive potencies of calcineurin inhibitors against the mitogen-induced blastogenesis of peripheral-blood mononuclear cells of myasthenia gravis patients. | The calcineurin inhibitors, tacrolimus and ciclosporin, are two useful immunosuppressive drugs for the treatment of myasthenia gravis (MG), for patients who have low responses to glucocorticoids. We have studied the suppressive potencies of tacrolimus and ciclosporin on concanavalin A-induced blastogenesis of periphera... | 18,812,027 |
Effect of hesperetin, a citrus flavonoid, on bacterial enzymes and carcinogen-induced aberrant crypt foci in colon cancer rats: a dose-dependent study. | Hesperetin, an important bioactive compound in Chinese traditional medicine, has antioxidant and anticarcinogenic properties. Hesperetin is found in abundance in orange and grape juices (200-590 mg L(-1)) consumed in the daily diet. We have investigated the effect of different doses of hesperetin on faecal and colonic ... | 18,812,032 |
Genetic diversity in clinical Mycobacterium tuberculosis isolates from Punjab. | Two hospitals, Sri Guru Ram Das Institute of Medical Sciences and Research and the TB and Chest Hospital, Amritsar, Punjab. To explore genetic diversity among the clinical Mycobacterium tuberculosis isolates prevalent in Punjab. Fifty-six random clinical isolates of M. tuberculosis were cultured from the sputum specime... | 18,812,040 |
The epidemiology of tuberculosis in Ottawa, Canada, 1995-2004. | In Ottawa (population 774,072), active tuberculosis (TB) cases are reported to Ottawa Public Health. There has been no comprehensive local epidemiological analysis to date. We report the epidemiology of TB in Ottawa and identify areas of improvement. We reviewed TB cases reported to the Reportable Disease Information S... | 18,812,041 |
Treatment outcome and follow-up of multidrug-resistant tuberculosis patients, West Coast/Winelands, South Africa, 1992-2002. | Brooklyn Chest Hospital, Western Cape, South Africa. To evaluate the treatment outcome and 2- and 5-year follow-up of patients treated for multidrug-resistant tuberculosis (MDR-TB) with individualized regimens. Retrospective cohort study of all MDR-TB patients starting treatment during 1992-2002. Patients were evaluate... | 18,812,049 |
Costs and cost-effectiveness of tuberculosis cultures using solid and liquid media in a developing country. | The expansion of culture has been proposed to aid tuberculosis (TB) control in developing countries. To examine the cost and cost-effectiveness at the Zambian National TB Reference Laboratory of homemade and commercially produced Löwenstein-Jensen culture (HLJ and CLJ) as well as automated and manually read liquid cult... | 18,812,051 |
Motor proteins: myosin mechanosensors. | Mechanosensation is emerging as a general principle of myosin motors. As demonstrated in a recent study, the single-headed myosin I molecule is an exquisite mechanosensor, able to sense strain over a very small force range. | 18,812,080 |
Behavioural genetics: the social fly. | Two studies report the presence of a social influence on pheromonal communication in fruit flies, demonstrating that the production of pheromone blends and mating behaviour are profoundly influenced by social context. | 18,812,081 |
Sporulation: SpoIIIE is the key to cell differentiation. | Sporulation in Bacillus subtilis requires asymmetric cell division, chromosome transfer into the spore and establishment of differential gene expression patterns. Several recent studies highlight the key roles of the SpoIIIE motor in this process. | 18,812,085 |
Combined phacoemulsification and transpupillary removal of heavy silicone oil. | We describe a technique for heavy silicone oil removal combined with phacoemulsification and intraocular lens insertion without scleral incisions or sutures using a modified 16-gauge cannula. The technique is less invasive than other techniques for removing silicone oil and does not interfere with the uveal tract or th... | 18,812,112 |
Corneal wavefront-guided photorefractive keratectomy in patients with irregular corneas after corneal refractive surgery. | To evaluate the corrective potential of corneal wavefront-guided photorefractive keratectomy (PRK) in patients with high levels of corneal aberrations and symptoms after previous corneal refractive surgery. Vissum-Instituto de Oftalmológico de Alicante, Alicante, Spain. This study comprised 25 eyes (20 patients) that h... | 18,812,125 |
Methicillin-resistant Staphylococcus aureus endophthalmitis after phacoemulsification in a continuous ambulatory peritoneal dialysis patient. | We report a case of methicillin-resistant Staphylococcus aureus (MRSA) endophthalmitis after phacoemulsification in a continuous ambulatory peritoneal dialysis (CAPD) patient with a history of MRSA infection. This case raised the problem of preoperative identification and subsequent management of MRSA carrier status, w... | 18,812,138 |
ACR Appropriateness Criteria on Hodgkin's lymphoma: favorable prognosis stage I and II. | The treatment for favorable-prognosis stage I and II Hodgkin's lymphoma has evolved over the past several years. Studies have attempted to reduce long-term treatment-related side effects, such as second malignancies and cardiac toxicity, through reduced chemotherapy or reduced radiotherapy. Randomized trials have compa... | 18,812,149 |
MUC1 intra-cellular trafficking is clathrin, dynamin, and rab5 dependent. | MUC1, a transmembrane glycoprotein, is abnormally over-expressed in most human adenocarcinomas. MUC1 association with cytoplasmic cell signal regulators and nuclear accumulation are important for its tumor related activities. Little is known about how MUC1 translocates from the cell membrane to the cytoplasm. In this s... | 18,812,166 |
Wild-type p53 in cancer cells: when a guardian turns into a blackguard. | The tumor suppressor p53 controls a broad range of cellular responses. Induction of a transient (cell cycle arrest) or a permanent (senescence) block of cell proliferation, or the activation of cell death pathways in response to genotoxic stress comprise the major arms of the survival-death axis governed by p53. Due to... | 18,812,169 |
Role of loops in the guanine quadruplex formation by DNA/RNA hybrid analogs of G4T4G4. | CD spectroscopy, gel electrophoresis and absorption-based thermal stability were used to analyze quadruplex formation of RNA and RNA/DNA hybrid analogs of the deoxyoligonucleotide G4T4G4, which forms a well-characterized basket-type quadruplex. All RNA-containing dodecamers, g4u4g4, G4u4G4 and g4T4g4 (RNA lower-case, D... | 18,812,187 |
Rheological investigation on hyaluronan-fibrinogen interaction. | This paper concerns the interaction between hyaluronan and fibrinogen as model for protein-polysaccharide interaction. From rheological investigation, it is shown that a 3D physical network is promoted by mixing the two components; the mechanism is attributed to electrostatic interactions. The influences of the molecul... | 18,812,188 |
The toxicology of Clioquinol. | 5-Chloro-7-iodo-quinolin-8-ol (Clioquinol) is a halogenated 8-hydroxyquinoline that was used in 1950-1970s as an oral anti-parasitic agent for the treatment and prevention of intestinal amebiasis. However in the 1970s oral Clioquinol was withdrawn from the market due to reports of neurotoxicity in Japanese patients. Re... | 18,812,216 |
Harmonic scalpel versus conventional electrosurgery in the treatment of vulvar cancer. | To compare differences in blood loss, operative time, and intra- and postoperative complications with the harmonic scalpel or conventional electrosurgery in the treatment of vulvar cancer. Consecutive patients who underwent radical vulvectomy with inguinal lymphadenectomy using the harmonic scalpel (HS) or conventional... | 18,812,244 |
Ultrasonic dyeing of cationized cotton fabric with natural dye. Part 1: cationization of cotton using Solfix E. | The dyeing of cationized cotton fabric with Solfix E using colouring matter extracted from Cochineal dye has been studied using both conventional and ultrasonic techniques. Factors affecting dye extraction such as ultrasound power, particle size, extraction temperature and time were studied. The results indicated that ... | 18,812,264 |
Analysis of depth of anesthesia with Hilbert-Huang spectral entropy. | Monitoring the effect of anesthetic drug on the neural system is an ongoing challenge for anesthetists. Several methods based on the electroencephalogram (EEG) have been proposed to estimate the depth of anesthesia (DoA); for instance, the Fourier-based time-frequency balanced spectral entropy as implemented in the Dat... | 18,812,265 |
Transferring disease management and health promotion programs to other countries: critical success factors. | Governments and health service providers around the world are under pressure to improve health outcomes while containing rising healthcare costs. In response to such challenges, many regions have implemented services that have been successful in other countries-but 'importing' initiatives has many challenges. This arti... | 18,812,326 |
Infarction-exclusion technique with the on-pump beating heart approach for ventricular septal perforation. | We report a successful surgical management of postinfarction ventricular septal perforation by infarction-exclusion technique with the on-pump beating heart approach and concomitant coronary artery bypass grafting. The identification of the suture line by direct inspection and finger palpation could be more accurate in... | 18,812,330 |
Vacuum-assisted closure for mediastinitis after pediatric cardiac surgery. | Two children, aged 1 and 14 years with methicillin-resistant Staphylococcus aureus mediastinitis after pediatric open-heart surgery, were fitted with a vacuum-assisted closure system. Complete healing was achieved in both cases, and primary wound closure could be carried out without an omental flap after 6 and 16 days. | 18,812,337 |
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