title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Edema caused by continuous epidural hydromorphone infusion: a case report and review of the literature. | Intraspinal drug delivery (IDD) therapy has been increasingly employed in patients with intractable, nonmalignant pain. Before implantation of permanent intraspinal pump, an intraspinal opioid screening trial is conducted to demonstrate the efficacy. The patient-controlled continuous epidural opioid infusion trail, per... | 18,837,206 |
[Early glottic cancer--treatment results]. | Early glottic cancer (stage T1, T2) is connected with very good prognosis as well as organ and function preservation. The aim of the study was the assessment of early glottic treatment results. Between 1999-2005 1007 patients with larynx cancer were treated in Dept. of Otolaryngology Head Neck Oncological Surgery Pozna... | 18,837,217 |
[The analysis of the bacterial and fungal flora in maxillary sinuses in patients operated due to FESS method]. | The aim of this work was to analyse the bacterial and fungal flora in maxillary sinuses in patients operated due to the FESS method. Studies were conducted on 110 patients, including 47 women aged 17-78 and 63 men aged 17-66, who underwent endoscopic surgical procedures due to chronic polypoid maxillary sinusitis betwe... | 18,837,224 |
[Own experience in stapes revision surgery--analysis of indications]. | Analysis of indications for stapes revision surgery in patients qualified for the secondary procedure at the Otosurgery Dept. Medical University of Lodz. 25 cases of stapes revision surgery out of the 385 total treated surgically otosclerosis cases are discussed. In group A (patients after total stapedectomy) the follo... | 18,837,226 |
Comparison of NSAID consumption in Slovakia, Finland and Norway. | Non-steroidal anti-inflammatory drugs (NSAIDs) belong to most frequently used drugs worldwide. NSAIDs belong to the family of drugs that represent the biggest drug risk as to the number of adverse drug reactions (ADRs), as well as to the number of deregistered drugs. We analysed the whole consumption of NSAIDs from ATC... | 18,837,248 |
Early (1 hour) post-operative parathyroid hormone (PTH) measurement predicts hypocalcaemia after thyroidectomy: a prospective case-control single-institution study. | The aim of the study was to evaluate the efficacy of parathyroid hormone 1-hour assay for the early prediction of hypoparathyroidism after thyroidectomy. Candidates for total, subtotal, completion thyroidectomy or lobectomy were entered into the study. Pre- and postoperative calcium and parathyroid hormone (1 hour and ... | 18,837,252 |
Gallstone ileus: a rare cause of colon obstruction. Report of a case. | The colon is a rare site of gallstone ileus. We report the case of a woman with cholelithiasis who underwent a total colectomy and cholecystectomy for colon obstruction due to a gallstone impacted in the sigmoid colon narrowed by diverticulitis. | 18,837,260 |
[Intestinal endometriosis: a case report]. | Endometriosis is seldom of interest to the general surgeon, since it is generally an exclusively gynaecological condition. Atypical locations, however, do fall within the domain of general surgery. Extra-gynaecological endometriosis denotes an ectopic localization of functional endometrial tissue, a finding whose incid... | 18,837,264 |
Research on immigrant earnings. | As the first in a trio of pieces devoted to incorporating immigration into policy models, this review of research on immigrant earnings trajectories brings to light several findings. Controlling for demographic and human capital characteristics, immigrants often start their U.S. lives at substantially lower earnings, b... | 18,837,270 |
Adding immigrants to microsimulation models. | Forecasts of the financial status of Social Security's Old-Age, Survivors, and Disability Insurance (OASDI) programs and forecasts of the effects of various OASDI policy options on Americans would be improved if information about the earnings and labor force behavior of various population subgroups were included in pro... | 18,837,271 |
Reversibility testing in patients with asthma and COPD. | This article examines the difference between chronic obstructive pulmonary disease and asthma, the use of reversibility testing and the various guidelines available to help healthcare professionals diagnose and treat patients with these conditions. | 18,837,279 |
[Biomass structure analysis of Atractylodes lancea in different ecological environments]. | To study the ecological environments of Atractylodes lancea by biomass structural analysis. Through the scientific investigation in Maoshan, the sampling spots were set up, the relation between growth and ecological environments was researched and the ecological environments of A. lancea were divided as following: the ... | 18,837,303 |
[Effect of weiganli on level of FL in bone marrow and serum of myelosuppressed anemic mice]. | To study the effect of Weiganli on the level of FL in bone marrow and serum of myelosuppressed anemic mice, and to explore it's function on hematopoietic regulation. Models of myelosuppressed anemic mice were induced by radiation and chemotherapeutic drug, and the mice were randomly divided into normal group, myelosupp... | 18,837,322 |
[Absorption of triterpenoid compounds from Indian bread (Poria cocos) across human intestinal epithelial (Caco-2) cells in vitro]. | To study the absorption of 3-epidehydrotumulosic acid (EDHTA), polyporenic acid C (PPAC) and 6alpha-hydroxypolyporenic acid C (HPPA) isolated from the sclerotium of Poria cocos. In human intestinal epithelial. By using Caco-2 (the human colonic adenocarcinoma cell lines) cells monolayer as an intestinal epithelial cell... | 18,837,324 |
[Effects of guanxin II on cardiac protein expression after acute myocardial ischemia on rats]. | Guanxin II is a famous modern formula of traditional Chinese medicine. Guanxin II after myocardial infarction (MI) has been shown to have beneficial effects on cardiac anatomy and function. The purpose of this study was to examine the effects of Guanxin 1I on cardiac protein expression after MI. Rats were randomized in... | 18,837,326 |
[Textural research on "Xuelihua" in "Bencao Gangmu Shiyi" (A Supplement to the Compendium of Materia Medica)]. | To investigate the historical origins of folk herbal medicine 'Xuelihua', the origin of 'Xuelihua' was confirmed by textural, botanical characteristics research, investigation of therapeutic effects and field survey. The 'Xuelihua' which was originally recorded in 'Bencao Gangmu Shiyi' (A Supplement to the Compendium o... | 18,837,331 |
[Study of using shattering extraction with solvent to extract ingredient of three kinds of traditional Chinese medicine]. | To prove if it is possible for using the shattering extraction with solvent to extract ingredients of traditional Chinese medicine. The shattering extraction with solvent, the refluxing extraction and the ultrasonic extraction were used to extract paeoniflorin from Radix Paeoniae rubra, and to extract baicalein from Ra... | 18,837,338 |
[Expression and activity analysis of interferonalpha-con and thymosin-alpha1]. | This study aimed to obtain recombinant fusion protein of thymosin alphal(TM-alpha1) and consensus IFNalpha (IFNalpha-con) which have bath TM-alpha1 and IFNalpha-con activities. The DNA sequence for the fusion protein was cloned into expression vector of pET-22b (+) and expressed in BL21 (DE3)-Codon plus-RP-X. The expre... | 18,837,390 |
Umbilical venous volume flow in twin-twin transfusion syndrome. | To examine umbilical venous volume flow (UVF) dynamics by twin status and disease severity in untreated twin-twin transfusion syndrome (TTTS). In 70 cases of untreated TTTS, absolute UVF, UVF corrected for estimated fetal weight (UVF/kg), intertwin difference (DeltaUVF/kg) and recipient to donor ratio (R/D-UVF/kg) were... | 18,837,441 |
Micro-computed tomographic analysis of bone healing subsequent to graft placement. | A micro-computed tomographic (muCT) analysis of bone healing subsequent to graft (tri calcium phosphate/TCP) placement in the maxillary sinus prior to dental endosteal implant placement was the focus of the current study. Ten trephined rod shaped human bone cores were obtained three months after the placement of partic... | 18,837,447 |
Oxidoreductase activities of polyclonal IgGs from the sera of Wistar rats are better activated by combinations of different metal ions. | It was shown that IgGs purified from the sera of healthy Wistar rats contain several different bound Me2+ ions and oxidize 3,3'-diaminobenzidine through a H2O2-dependent peroxidase and H2O2-independent oxidoreductase activity. IgGs have lost these activities after removing the internal metal ions by dialysis against ED... | 18,837,443 |
Partially polyurethane-covered stent for cerebral aneurysm treatment. | Partially polyurethane-covered stent (PPCS) is proposed for the treatment of cerebral aneurysms. The PPCSs were observed to substantially modify the flow entering the aneurysm in a patient-specific aneurysm phantom (PSAP). These stents can act as flow modulators and the polyurethane (PU) membrane can provide a smooth s... | 18,837,459 |
Regulation of beta-catenin and connexin-43 expression: targets for sphingolipids in colon cancer prevention. | Sphingolipid metabolites are generated throughout the intestinal tract after hydrolysis of orally administered complex sphingolipids and significantly suppress colon cancer in carcinogen-treated CF1 mice. In the present study, the mechanisms of tumor suppression by dietary sphingolipids were investigated. Changes in se... | 18,837,472 |
Effective diffusion coefficients for methanol in sulfuric acid solutions measured by Raman spectroscopy. | The diffusion of methanol into 0-96.5 wt % sulfuric acid solutions was followed using Raman spectroscopy. Because methanol reacts to form protonated methanol (CH 3OH 2 (+)) and methyl hydrogen sulfate in H 2SO 4 solutions, the reported diffusion coefficients, D, are effective diffusion coefficients that include all of ... | 18,837,493 |
Effects of epilactose on calcium absorption and serum lipid metabolism in rats. | Epilactose (4-O-beta-galactopyranosyl-D-mannnose) is a rare disaccharide in cow milk that can be synthesized from lactose by the cellobiose 2-epimerase of Ruminococcus albus. In this study, we examined the biological activities of epilactose using male Wistar-ST rats. The apparent rates of calcium and magnesium absorpt... | 18,837,503 |
A 200-antibody microarray biochip for environmental monitoring: searching for universal microbial biomarkers through immunoprofiling. | Environmental biomonitoring approaches require the measurement of either unequivocal biomarkers or specific biological profiles. Antibody microarrays constitute new tools for fast and reliable analysis of up to hundreds of biomarkers simultaneously. Herein we report 150 new polyclonal antibodies against microbial strai... | 18,837,515 |
Pt/glassy carbon model catalysts prepared from PS-b-P2VP micellar templates. | Poly(styrene)-block-poly(2-vinylpyridine) (PS-b-P2VP) diblock copolymer was used as a micellar template to fabricate arrays of Pt nanoparticles on mica and glassy carbon (GC) supports. Polymer micellar deposition yields Pt nanoparticles with tunable particle size and surface number density on both mica and GC. After de... | 18,837,528 |
Copper-catalyzed intramolecular N-vinylation of sulfonamides: general and efficient synthesis of heterocyclic enamines and macrolactams. | With the catalysis of CuI/N,N'-dimethylethylenediamine, intramolecular C-N coupling between sulfonamides and vinyl halides was successfully implemented, leading to the efficient synthesis of 5-, 6-, 7-, and even 8-membered heterocyclic enamines in both exo and endo modes. The bicyclic enamines thus formed provided a co... | 18,837,542 |
Qualitative mapping of structurally different dipeptide nanotubes. | Biological self-assembled structures are receiving increasing focus within micro- and nanotechnology, for example, as sensing devices, due to the fact that they are cheap to produce and easy to functionalize. Therefore, methods for the characterization of these structures are much needed. In this paper, electrostatic f... | 18,837,544 |
Studies of carbon incorporation on the diamond [100] surface during chemical vapor deposition using density functional theory. | Accurate potential energy surface calculations are presented for many of the key steps involved in diamond chemical vapor deposition on the [100] surface (in its 2 x 1 reconstructed and hydrogenated form). The growing diamond surface was described by using a large (approximately 1500 atoms) cluster model, with the key ... | 18,837,545 |
Open bridge-structured gold nanoparticle array for label-free DNA detection. | We focused on changes in the electrical property of the open bridge-structured gold nanoparticles array consisting of 46-nm parent and 12-nm son gold nanoparticles by hybridization and applied it for a simple electrical DNA detection. Since a target DNA of a 24-mer oligonucleotide was added to the probe DNA modified 12... | 18,837,561 |
A new mermithid nematode in imagos of Cladopelma collator (Townes) (Diptera: Chironomidae) eclosing from waterways in northern Minnesota. | Octomyomermis connellyi n. sp. (Nematoda: Mermithidae) is described from the hemocoel of male and female imagos of Cladopelma collator (Townes) eclosing from Lake Ozawindib and from Gulsvig Landing in the upper Mississippi River in northern Minnesota. The species is distinguished from the other species in the genus. In... | 18,837,568 |
Does precontemplation represent a homogeneous stage category? A latent class analysis on German smokers. | The authors examined the subtype structure of smokers classified in the precontemplation stage of change within the transtheoretical model. From a general practice-based sample of 1,499 daily smoking patients from Germany (participation rate 80%), they used a subgroup of 929 smokers who were classified in the precontem... | 18,837,601 |
Cognitive-behavioral therapy for intermittent explosive disorder: a pilot randomized clinical trial. | No randomized clinical trials have evaluated the efficacy of psychotherapy for intermittent explosive disorder (IED). In the present study, the authors tested the efficacy of 12-week group and individual cognitive-behavioral therapies (adapted from J. L. Deffenbacher & M. McKay, 2000) by comparing them with a wait-... | 18,837,604 |
Teacher key opinion leaders and mental health consultation in low-income urban schools. | Diffusion theory posits that information is disseminated throughout a social network by the persuasion of key opinion leaders (KOLs). This study examined the relative and combined influence of peer-identified KOL teachers (n = 12) and mental health providers (n = 21) on classroom teachers' (n = 61) self-reported use of... | 18,837,608 |
Interpretation bias in social anxiety as detected by event-related brain potentials. | Little is known about psychophysiological correlates of interpretation bias in social anxiety. To address this issue, the authors measured event-related brain potentials (ERPs) in high and low socially anxious individuals during a task wherein ambiguous scenarios were resolved with either a positive or negative ending.... | 18,837,619 |
Ezetimibe 5 and 10 mg for lowering LDL-C: potential billion-dollar savings with improved tolerability. | To compare the clinical efficacy of ezetimibe 5 mg (prescribed as a 10-mg tablet split in half) with a whole 10-mg tablet. From January 2003 through July 2005, all Bronx Veterans Administration ezetimibe prescriptions were for 10 mg. In August 2005, it was mandated that all new ezetimibe prescriptions be 5 mg, prescrib... | 18,837,641 |
Connected culture of murine hepatocytes and HUVEC in a multicompartmental bioreactor. | A multicompartmental bioreactor was conceived and designed to mimic cross talk between cells in different culture chambers connected only by flow, such that cell-cell interaction is mediated by soluble ligands as occurs in the body. The system was tested with a connected culture of murine hepatocytes and human umbilica... | 18,837,649 |
Anti-oxidized low-density lipoprotein antibody levels are associated with the development of type 2 diabetes mellitus. | Anti-oxidized low-density lipoprotein (LDL) antibodies are associated with the oxidative capacity of plasma, but whether they protect or promote diabetes is unknown. We undertook a prospective study to determine the predictive capacity of anti-oxidized LDL antibodies for the onset of type 2 diabetes mellitus (T2DM). We... | 18,837,736 |
A novel antagonist of prostaglandin D2 blocks the locomotion of eosinophils and basophils. | Chemoattractant receptor homologous molecule of Th2 cells (CRTH2) has been shown to mediate the chemotaxis of eosinophils, basophils and Th2-type T lymphocytes. The major mast cell product prostaglandin (PG) D(2) is considered to be the principal ligand of CRTH2. We developed a novel CRTH2 antagonist, AZ11665362 [2,5-d... | 18,837,743 |
Low-molecular-weight heparin for routine hemodialysis. | Unfractionated heparin (UFH) is a series of molecules, and as such has variable pharmacodynamics. Low-molecular-weight heparins were developed to improve both drug pharmacokinetics and dynamics, so as to provide a reliable clinical effect. These are potent agents, but have an increased half-life compared with UFH in di... | 18,837,768 |
Orally administrated Juzen-taiho-to/TJ-48 ameliorates erythropoietin (rHuEPO)-resistant anemia in patients on hemodialysis. | Maintenance of the red blood cell volume is a fundamental aspect of ensuring oxygen supply to the tissue. Recombinant human erythropoietin (rHuEPO) was approved for marketing in Japan in 1990 for the treatment of anemia in patients on dialysis. Recombinant human erythropoietin caused a significant increase in hemoglobi... | 18,837,771 |
Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response. | Immunization with high doses of irradiated sporozoites delivered by the bites of infected mosquitoes has been shown to induce protective responses against malaria, mediated in part by CD8(+) T cells. In contrast, natural transmission involving low exposure to live sporozoite antigen fails to elicit strong immunity. In ... | 18,837,788 |
Effect of weight loss on markers of triglyceride-rich lipoprotein metabolism in the metabolic syndrome. | Hypertriglyceridaemia, a consistent feature of dyslipidaemia in the metabolic syndrome (MetS), is related to the extent of abdominal fat mass and altered adipocytokine secretion. We determined the effect of weight loss by dietary restriction on markers of triglyceride-rich lipoprotein (TRL) metabolism and plasma adipoc... | 18,837,799 |
Apoptotic effect of Helicobacter pylori on oesophageal squamous-cell carcinoma cells in vitro. | The relationship between Helicobacter pylori (Hp) infection and oesophageal squamous-cell carcinoma (ESCC) risk is still inconclusive. Our previous study found an inverse association between the two, but its mechanism is still unknown. Thus, we conducted in vitro studies to clarify the issue. One ESCC (CE 81T/VGH) cell... | 18,837,801 |
Has the time come to control hepatitis A globally? Matching prevention to the changing epidemiology. | For the first time a global meeting on hepatitis A virus (HAV) infection as vaccine preventable disease was organized at the end of 2007. More than 200 experts from 46 countries gathered to investigate the changing global HAV epidemiology reflecting the increasing numbers of persons at risk for severe clinical disease ... | 18,837,827 |
Acute amiodarone-induced pulmonary toxicity: an association of risk factors in a child operated by arterial switch operation. | Amiodarone is an antiarrhythmic benzoflurane drug with an imposing adverse effect profile. Amiodarone pulmonary toxicity is the major complication. It is well described in adults, whereas it is extremely rare in pediatric patients. This is a case of a child with supraventricular tachycardia post repair of transposition... | 18,837,818 |
Changing epidemiology of hepatitis A in Brazil: reassessing immunization policy. | Recent studies have shown that the prevalence of antibody to hepatitis A virus (HAV) is decreasing in several Latin American countries. Brazil is a very large and heterogeneous country, showing striking regional differences. With regard to sanitary facilities, 81.7% of the districts in the south-eastern region have sew... | 18,837,829 |
Hypersensitivity myocarditis presenting as atrioventricular block and wide complex tachycardia in a toddler. | A 13-month-old boy presented with acute onset of complete atrioventricular block and wide complex tachycardia but normal hemodynamics. Endomyocardial biopsy disclosed active myocarditis with eosinophils, suggesting a hypersensitivity reaction. With no treatment, the rhythm disturbance resolved within days of onset. Our... | 18,837,817 |
Hepatitis A acute liver failure: follow-up of paediatric patients in southern Brazil. | We retrospectively analysed 33 children and adolescents who had been hospitalized in a liver transplant unit within the previous 10 years for acute liver failure (ALF). The patients' age varied between 2 months and 15 years of age (median 6.2 +/- 5.3), and 21 (63%) were male. Thirteen patients (39%) were immunoglobulin... | 18,837,838 |
Male sex and pre-existing diabetes are independent risk factors for stillbirth. | To determine whether the risk of stillbirth is associated with male fetal sex, fetal growth and maternal factors in an Australian population. A retrospective secondary data analysis of 16 445 singleton births was performed using a tertiary referral centre obstetric database (1995-1999). Univariate and multiple logistic... | 18,837,843 |
Antenatal topographical assessment of placenta accreta with ultrasound. | The major risk of placenta accreta is severe haemorrhage when the placenta is separated at delivery. A case series of placenta accreta with antenatal sonographic topographical assessment of myometrial involvement is presented. The extent of myometrial involvement and the vascularity could be assessed by the observation... | 18,837,849 |
Regional brain changes in bipolar I depression: a functional magnetic resonance imaging study. | To investigate neural activity in prefrontal cortex and amygdala during bipolar depression. Eleven bipolar I depressed and 17 normal subjects underwent functional magnetic resonance imaging (fMRI) while performing a task known to activate prefrontal cortex and amygdala. Whole brain activation patterns were determined u... | 18,837,865 |
Role of Tc99m MIBI SPECT in the assessment of treatment response in pharyngeal carcinoma. | The purpose of this study was to compare Tc(99m) MIBI SPECT imaging with computed tomography (CT) for assessment of post-radiotherapy treatment response in pharyngeal carcinoma. Twenty-two subjects took part in this study, which included six patients with nasopharyngeal carcinoma (Group I), three patients with orophary... | 18,837,883 |
Selective surgical management of well-differentiated thyroid cancer. | There has been a rapid rise in the incidence of thyroid cancer in the United States, along with more incidentalomas of the thyroid. Treatment of thyroid cancer revolves around appropriate surgical intervention, minimizing complications, and the use of adjuvant therapy in select circumstances. Prognostic features and ri... | 18,837,884 |
Cancer pain and analgesia. | Pain ranges in prevalence from 14-100% among cancer patients and occurs in 50-70% of those in active treatment. Cancer pain may result from direct invasion of tumor into nerves, bones, soft tissue, ligaments, and fascia, and may induce visceral pain through distension and obstruction. Cancer pain is multifaceted. Clini... | 18,837,907 |
Metabolic DNA as the origin of spontaneously released DNA? | A DNA fraction is spontaneously released from living, but not dead or dying, human, other mammalian, avian, amphibian, plant, and prokaryote cells. The spontaneously released DNA fraction has been shown to be (a) present in both actively dividing and nondividing, differentiated cell populations; (b) labile; (c) associa... | 18,837,918 |
Circulating nucleic acids in the assessment of endogenous growth hormone production. | There is growing concern about the use of recombinant human growth hormone (rhGH) by individuals taking part in competitive sports. Although rhGH is banned by the international organizations, the detection of GH doping is difficult. We postulated that rhGH will suppress endogenous GH production, which can be assessed b... | 18,837,926 |
Point-of-admission hypothermia among high-risk Nigerian newborns. | Facilities which manage high-risk babies should frequently assess the burden of hypothermia and strive to reduce the incidence. To determine the incidence and outcome of point-of-admission hypothermia among hospitalized babies. The axillary temperatures of consecutive admissions into a Nigerian Newborn Unit were record... | 18,837,973 |
The role of positive selection in determining the molecular cause of species differences in disease. | Related species, such as humans and chimpanzees, often experience the same disease with varying degrees of pathology, as seen in the cases of Alzheimer's disease, or differing symptomatology as in AIDS. Furthermore, certain diseases such as schizophrenia, epithelial cancers and autoimmune disorders are far more frequen... | 18,837,980 |
Pica and refractory iron deficiency anaemia: a case report. | Iron deficiency is the most common cause of anaemia worldwide. Pica, the ingestion of substances that are inappropriate for consumption, is associated with iron deficiency and may be under-diagnosed. A 34-year-old woman presented with iron deficiency anaemia refractory to treatment for more than a decade. The clinical ... | 18,838,005 |
The effect of coaching on the simulated malingering of memory impairment. | Detecting malingering or exaggeration of impairments in brain function after traumatic brain injury is of increasing importance in neuropsychological assessment. Lawyers involved in brain injury litigation cases routinely coach their clients how to approach neuropsychological testing to their advantage. Thus, it is imp... | 18,838,010 |
Multi-jurisdictional investigation of interactive fountain-associated cryptosporidiosis and salmonellosis outbreaks. | Interactive water fountains are established sources of gastrointestinal infections yet most health codes fail to regulate their design and operation. This report describes multi-agency, concurrent interactive fountain-associated cryptosporidiosis and salmonellosis outbreak investigations and highlights the need for the... | 18,838,018 |
Creation of an intraatrial tunnel to produce a total cavo-pulmonary connection in a patient with dominant right ventricle, totally anomalous pulmonary venous connection, and pulmonary atresia with non-confluent pulmonary arteries. | The surgical strategy for patients having a functionally single ventricle associated with totally anomalous pulmonary venous connection and pulmonary atresia with non-confluent pulmonary artery has yet to be agreed. We created an intraatrial tunnel to produce a total cavo-pulmonary connection in such a patient, also cr... | 18,838,024 |
Food patterns and Mediterranean diet in western and eastern Mediterranean islands. | To assess current Mediterranean dietary patterns (MDP) in the western and eastern Mediterranean, i.e. in Balearic islanders (BI) and Greek islanders (GI). Dietary patterns were assessed using FFQ on a representative sample (n 1200) of the BI and GI (n 1324) adult population. A Mediterranean Diet Score (MDS) was calcula... | 18,838,026 |
From emotion resonance to empathic understanding: a social developmental neuroscience account. | The psychological construct of empathy refers to an intersubjective induction process by which positive and negative emotions are shared, without losing sight of whose feelings belong to whom. Empathy can lead to personal distress or to empathic concern (sympathy). The goal of this paper is to address the underlying co... | 18,838,031 |
Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia. | Schizophrenia has been thought of as a disorder of reduced functional and structural connectivity. Recent advances in neuroimaging techniques such as functional magnetic resonance imaging, structural magnetic resonance imaging, diffusion tensor imaging, and small animal imaging have advanced our ability to investigate ... | 18,838,043 |
Attrition and related trends in scientific rigor: a score card for ART adherence intervention research and recommendations for future directions. | Scientific rigor in intervention trials is frequently used in systems that identify effective interventions for dissemination. In these systems, and in work that synthesizes bodies of research, percent attrition is often considered a fatal threat to validity. However, differential attrition, versus percent total, is of... | 18,838,057 |
The information-motivation-behavioral skills model of antiretroviral adherence and its applications. | Suboptimal adherence to highly active antiretroviral therapy (HAART) may have serious consequences for HIV patients, and for public health overall. The Information-Motivation-Behavioral Skills (IMB) model of HAART adherence can be used to understand the dynamics of HAART adherence and to intervene with patients to prom... | 18,838,059 |
Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-kappaB in RAW 264.7 cells. | Induction of inducible nitric oxide synthase (iNOS) expression and nitric oxide (NO) production is thought to have beneficial immunomodulatory effects in acute and chronic inflammatory disorders. In Raw 264.7 cells stimulated with lipopolysaccharide (LPS) to mimic inflammation, withaferin A inhibited LPS-induced expres... | 18,838,070 |
Lidocaine affects the redox environment and the antioxidant enzymatic system causing oxidative stress in the hippocampus and amygdala of adult rats. | Our objective was to investigate if oxidative stress is involved in the neural damage caused by lidocaine. Male Wistar rats were used. The control group received 0.9% saline ip and the treated group received a single 60 mg/kg lidocaine dose ip. On days 1, 2, 5, and 10 after dosing, ten rats were sacrificed and their br... | 18,838,081 |
Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications. | Chitosan is a natural based polymer, obtained by alkaline deacetylation of chitin, which presents excellent biological properties such as biodegradability and immunological, antibacterial and wound-healing activity. Recently, there has been a growing interest in the chemical modification of chitosan in order to improve... | 18,838,086 |
Identification of a novel DPA1 allele, DPA1*010602, in an East African population. | We report here a novel DPA1 allele, DPA1*010602, which was identified from an East African population during sequence-based human leukocyte antigen DPA1 typing. Through cloning and sequencing of multiple clones we confirmed that the new allele is identical to DPA1*010301 at exon 2 with the exception of two nucleotide s... | 18,838,095 |
Neuroprotective effects of berberine on stroke models in vitro and in vivo. | Berberine is an alkaloid derived from herb medicine Coptidis Rhizom. Although there are increasing evidences that berberine exhibits neuroprotective effects against ischemic brain damage, little is known about the mechanism. In this study, we investigated the effect of berberine on ischemic injury in a middle cerebral ... | 18,838,103 |
NaCl preference and water intake effects of food availability in median eminence polydipsia. | Lesions in the median eminence (ME) produce a well-known neurological model of polydipsia and polyuria in rats. The effect of food availability (ad lib/deprivation) on the polydipsic/polyuric behaviour of animals was tested. As expected, all lesioned rats developed strong polyuria and polydipsia during the first postop... | 18,838,106 |
Distribution of two-pore-domain potassium channels in the adult rat vestibular periphery. | Constitutively active background or "leak" two-pore-domain potassium (K(+)) channels (Kcnk family), as defined by lack of voltage and time dependency are central to electrical excitability of cells by controlling resting membrane potential and membrane resistance. Inhibition of these channels by several neurotransmitte... | 18,838,117 |
The good work--a Swedish trade union vision in the shadow of lean production. | "The Good Work" (Det goda arbetet) was established as a highly praised and established concept in the Swedish working life debate in the middle of the 1980s. In this paper, we are going to discuss the concept in relation to the massive introduction of lean production in Swedish industry. The aim of this paper is to res... | 18,838,130 |
Different kinetics of cholesterol delivery to components of the cholesterol homeostatic machinery: implications for cholesterol trafficking to the endoplasmic reticulum. | Previously, using an oxysterol to induce cholesterol trafficking to the Endoplasmic Reticulum (ER), we reported a dissociation between cholesterol transport to two important cholesterol regulatory components in the ER: the cholesterol esterifying enzyme ACAT (Acyl CoA:Cholesterol Acyltransferase) and the membrane-bound... | 18,838,129 |
Enantioselective chromatography-a powerful tool for the discrimination of biotic and abiotic transformation processes of chiral environmental pollutants. | On the basis of the general principles of chirality the characteristics of chromatograms obtained by enantioselective GC and HPLC are explained, followed by a description of different enantioselective chromatographic methods (HPLC, high-resolution GC, multidimensional GC, CE, supercritical fluid chromatography) thus fa... | 18,838,139 |
Analysis of minor flavonoids in Piper hostmannianum var. berbicense using liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometry. | The fragmentations of hydroxylated flavanones, chalcones and dihydrochalcones were investigated by direct loop injection using an ion trap mass spectrometry equipped with atmospheric pressure chemical ionization (APCI) probe. Some of them have been isolated from the leaves of Piper hostmannianum var. berbicense and sta... | 18,838,145 |
Cardiac parasympathetic dysfunction concurrent with cardiac sympathetic denervation in Parkinson's disease. | We aimed to characterize the relationship between cardiac sympathetic and parasympathetic dysfunction employing cardiac (123)I-meta-iodobenzylguanidine (MIBG) uptake and other autonomic function parameters in Parkinson's disease (PD). 79 PD patients were studied. We performed (123)I-MIBG myocardial scintigraphy to asse... | 18,838,148 |
The effect of a low dose of transforming growth factor beta1 (TGF-beta1) on the early bone-healing around oral implants inserted in trabecular bone. | Transforming growth factor beta1 (TGF-beta1) has been shown to stimulate bone healing in several animal models and may influence bone response directly after implant installation. Aim of the present study is to investigate the effect of a low dose of TGF-beta1, on the early bone-healing around oral implants placed in t... | 18,838,161 |
The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles. | We report the formation of polysiloxane polymers containing embedded methylene blue and gold nanoparticles incorporated by a swell-encapsulation-shrink method. These polymers show significant antimicrobial activity against methicillin-resistant Staphylococcus aureus and Escherichia coli with up to a 3.5 log(10) reducti... | 18,838,166 |
Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade. | CD200 plays a key role in regulating the immune system and has been shown to be upregulated on the surface of different tumors including chronic lymphocytic leukemia. In this study we addressed the effects of CD200 over-expression in CLL cells on autologous T cells in a mixed lymphocyte reaction system. We used native ... | 18,838,168 |
Conformational changes involved in G-protein-coupled-receptor activation. | Little is known about the nature of the conformational changes that convert G-protein-coupled receptors (GPCRs), which bind diffusible ligands, from their resting into their active states. To gain structural insight into this process, various laboratories have used disulfide cross-linking strategies involving cysteine-... | 18,838,178 |
Activated carbon/iron oxide composites for the removal of atrazine from aqueous medium. | The adsorption features of activated carbon and the oxidation properties of iron oxides were combined in a composite to produce new materials for atrazine removal from aqueous medium. Activated carbon/iron oxide composites were prepared at 1/1 and 5/1 mass ratios and characterized with powder X-ray diffractometry (XRD)... | 18,838,216 |
The determination of hexavalent chromium (Cr6+) in electronic and electrical components and products to comply with RoHS regulations. | Toxicity of hexavalent chromium (Cr(6+)) was focused on with a publication of EU RoHS directive, a novel method to determine hexavalent chromium is developed. It is a combination of energy dispersion X-ray fluorescence spectrometry (EDXRF), spot test, alkali digestion and UV-vis spectrophotometric analysis. First, by E... | 18,838,223 |
Effects of obesity on neuroendocrine, cardiovascular, and immune cell responses to acute psychosocial stress in premenopausal women. | To analyze the neuroendocrine and immune cell responses to acute psychosocial stress in obese compared to non-obese premenopausal women. N=15 obese (BMI> or =30) and N=24 (BMI<30) non-obese premenopausal women underwent public speaking stress. State anxiety, ACTH, cortisol, and the redistribution of immune cells ... | 18,838,227 |
Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. | Experimental autoimmune uveoretinitis (EAU) is an animal model for human intraocular inflammatory disease. EAU is induced in B10.RIII mice by immunization with RBP-3 161-180 peptide and intraperitoneal pertussis toxin and is mediated by CD4(+) T cells that generate a clinically monophasic disease peaking approximately ... | 18,838,247 |
The autoimmunologist: geoepidemiology, a new center of gravity, and prime time for autoimmunity. | There are currently over 100 human diseases that are considered to be autoimmune or chronic inflammatory affecting 5-10% of the world population and spanning through all medical specialties. As a result, health care costs are enormous and the clinical management is often challenging, particularly considering the comorb... | 18,838,248 |
Glandular stem cells are a promising source for much more than beta-cell replacement. | Glandular stem cells (GSCs) can be obtained from exocrine glands such as pancreas or salivary glands using well-established cell culturing methods. The resulting cell populations are characterized by a high proliferative capacity and an unusually high plasticity. Cells from pancreas have been demonstrated to differenti... | 18,838,258 |
Bactericidal/permeability-increasing protein (BPI) and BPI homologs at mucosal sites. | At mucosal surfaces, we must co-exist with a high density of diverse microorganisms; therefore, protection against these occurs on multiple levels. Leukocyte- and epithelial derived-antimicrobial peptides and proteins (AMPs) comprise an essential component of immune defense. These molecules possess antibacterial, antif... | 18,838,299 |
Validated high performance liquid chromatography-UV detection method for the determination of daptomycin in human plasma. | Daptomycin is the first approved member of the new class cyclic lipopeptide antibiotic drugs, effective against a broad spectrum of Gram-positive bacteria. Here we present an HPLC method with UV detection capable to obtain pharmacokinetic data of daptomycin in human plasma, exemplarily shown in a critically ill patient... | 18,838,314 |
Supercritical fluid chromatography comparison of the poly(trans-1,2-cyclohexanediyl-bis acrylamide) (P-CAP) column with several derivatized polysaccharide-based stationary phases. | The poly(trans-1,2-cyclohexanediyl-bis acrylamide) (P-CAP) column has so far been primarily used with normal phase and polar organic mobile phase chromatography. Its use in supercritical fluid chromatography (SFC) was investigated via the analysis of 40 commercial and 100 proprietary compounds using a 12-min gradient w... | 18,838,315 |
Selective elimination of autoreactive T cells in vivo by the regulatory T cells. | How regulatory T cells (Treg) control autoreactive T cells has not been analyzed in animals with a normal T cell repertoire. Using endogenous viral superantigens (VSAg) as the primary self antigens and mice with the Scurfy mutation of FoxP3, we show here that the Treg defect causes preferential accumulation of autoreac... | 18,838,339 |
Biomechanical evaluation and comparison of polyetheretherketone rod system to traditional titanium rod fixation. | Polyetheretherketone (PEEK) has been increasingly used as a biomaterial for spinal implants. PEEK lumbar fusion rods have recently become available for use in posterior lumbar fusion procedures. To compare Polyetheretherketone Rod System to traditional titanium rod fixation in a cadaveric model and provide mechanical t... | 18,838,341 |
Exploring time series retrieved from cardiac implantable devices for optimizing patient follow-up. | Current cardiac implantable devices (IDs) are equipped with a set of sensors that can provide useful information to improve patient follow-up and prevent health deterioration in the postoperative period. In this paper, data obtained from an ID with two such sensors (a transthoracic impedance sensor and an accelerometer... | 18,838,359 |
The Berlin Brain--Computer Interface: accurate performance from first-session in BCI-naïve subjects. | The Berlin Brain--Computer Interface (BBCI) project develops a noninvasive BCI system whose key features are: 1) the use of well-established motor competences as control paradigms; 2) high-dimensional features from multichannel EEG; and 3) advanced machine-learning techniques. Spatio-spectral changes of sensorimotor rh... | 18,838,371 |
The Burroughs Wellcome Career Award in the Biomedical Sciences: challenges to and prospects for estimating the causal effects of career development programs. | The Career Award in Biomedical Sciences (CABS) was launched by the Burroughs Wellcome Fund to assist talented scientists to cross the "bridge" that connects postdoctoral training with independent investigator status. This study examines the causal effects of CABS, using both conventional methods and a newer method (pro... | 18,838,396 |
The nephrotic syndrome: an unusual case of multiple embolic events. | The nephrotic syndrome is an unusual cause of the hypercoaguable state and thromboembolic complications. Here we report the case of a 42-year-old woman with nephrotic syndrome who presented with a pulseless lower extremity and a midpole renal infarct requiring urgent embolectomy of the leg. During her embolic evaluatio... | 18,838,397 |
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