title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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[Leaching behavior of heavy metal elements in lead-free solders]. | Leaching behavior of heavy metal elements from Sn-3.5 Ag-0.5 Cu, Sn-3.5 Ag, Sn-0.5 Cu lead-free solders and their joints were investigated in typical acid, alkaline and saline corrosion solutions. It is found that for solder alloys, significant leaching of Sn was observed in NaCl saline solution, about two orders of ma... | 18,839,597 |
[Effects of substrate species on fermentative hydrogen production]. | Biohydrogen production by anaerobic sludge was studied by using wastewater as substrate in batch process. Hydrogen production potential of different substrate species, as well as the composition of fermentation product in liquid phase, was studied in the batch culture experiments. The hydrogen production and bacterial ... | 18,839,598 |
[Experimental study on methane potentials of source-separated BMW and individual waste materials]. | A laboratory procedure is described for measuring methane potentials of source-separated bio-organic municipal waste (BMW). Triplicate reactors with about 20 grams fresh material were incubated at 37 degrees C with 300 mL inoculum from Shenyang wastewater treatment plant and the methane production was followed over a 5... | 18,839,599 |
[Pore structure and desulfurization characteristics of organic calcium]. | Calcination of oganic calcium was carried out in fixed bed, pore structure of tested sample was analyzed with auto-adsorption analyzer, and desulfurization experiment was studied by intelligent sulfur determination analyzer. Specific surface area of calcium magnesium acetate (CMA) was 46.6 m2/g after calcination at 900... | 18,839,601 |
[Myocardial structure and function in patients with metabolic syndrome--echocardiographic and ergospirometric assessment]. | Presently a lot of studies focus on metabolic syndrome. There are new studies regarding the relationship between metabolic syndrome (MS) and changes in myocardial structure and function and subsequent development of heart failure. The aim of the study was to assess the myocardial structure and function, particularly di... | 18,839,607 |
Pattern of trauma to anterior segment of eyes in a tertiary eye care centre of Jharkhand. | Ocular trauma to anterior segment as an important cause of preventable morbidity to vision is commonly encountered in this tertiary care centre and requires a targeted approach for preventing visual impairment and loss to the population at large. To find out sociodemographic and clinical pattern of anterior segment inv... | 18,839,633 |
Early treatment with low fixed dose (5 mCi) radioiodine therapy is effective in Indian subjects with Graves' disease. | There is little consensus regarding the most appropriate dosage regimen for radioiodine treatment in Graves' disease. The authors evaluated the efficacy of low fixed dose (5mCi) of radioiodine therapy, in terms of its cure rate and promptness of control, as well possible factors influencing the outcome. One hundred and... | 18,839,646 |
Innovations in healthcare finance lessons from the 401(k) model. | *Escalating health benefit expenses are leading employers to shift more of the costs to their employees. *Global financial services companies and startup entrepreneurs are competing to develop private-sector solutions to capitalize on the ailing and mis-aligned healthcare financing system. *Emerging innovations are tar... | 18,839,661 |
Surviving in the age of price transparency. | *Healthcare organizations can develop a value-based pricing strategy that benefits both patients and the organization. *The value-based pricing strategy of the Cleveland Clinic is based on five key components of value-relationship to cost, payment considerations, quality, market tolerance, and consistency. *Seven inter... | 18,839,666 |
The sea change of the see-through hospital--and how to stay afloat. | In the new era of transparency, hospitals need to understand that payers, competitors, and consumers are looking closely at their clinical quality performance. That increased scrutiny promises financial consequences if hospitals fail to live up to their ideals. | 18,839,672 |
Modality distribution of sensory neurons in the feline caudate nucleus and the substantia nigra. | Despite extensive analysis of the motor functions of the basal ganglia and the fact that multisensory information processing appears critical for the execution of their behavioral action, little is known concerning the sensory functions of the caudate nucleus (CN) and the substantia nigra (SN). In the present study, we... | 18,839,694 |
The glutathione response to salt stress in the thermophilic fungus, Thermomyces lanuginosus. | In order to investigate the role of glutathione in response to salt stress in the thermophilic fungus, Thermomyces lanuginosus, the biomass and the intracellular pool of protein and the glutathione + glutathione disulphid (GSH + GSSG) was measured for four days in a medium with NaCl or KCl added and in the basal medium... | 18,839,702 |
The presenting complaints of low income adults for emergency dental care: an analysis of 35,000 episodes in Victoria, Australia. | This study examined the mix of presenting problems faced by a large diverse dental service treating low-income Australian adults and provides a basis for communities to understand and manage demand for dental services. A retrospective analysis in a state-wide multi-centre dental health service. Data for all patients (i... | 18,839,719 |
Prevalence of breath malodour in 7- 11-year-old children living in Middle Anatolia, Turkey. | To determine the prevalence of breath malodour and to assess the relationships between breath malodour parameters such as dental caries, habitual mouth breathing, tooth-brushing, and the frequency of upper respiratory-tract infection. A total of 628 healthy children (327 boys, 301 girls) ranging in age from 7 to 11 who... | 18,839,725 |
Person-centered work environments, psychological safety, and positive affect in healthcare: a theoretical framework. | We propose that in order to systematically improve healthcare quality, healthcare organizations (HCOs) need work environments that are person-centered: environments that support the careprovider as well as the patient. We further argue that HCOs have a moral imperative to provide a workplace where professional care sta... | 18,839,753 |
Tropical coastal habitats as surrogates of fish community structure, grazing, and fisheries value. | Habitat maps are frequently invoked as surrogates of biodiversity to aid the design of networks of marine reserves. Maps are used to maximize habitat heterogeneity in reserves because this is likely to maximize the number of species protected. However, the technique's efficacy is limited by intra-habitat variability in... | 18,839,764 |
Fine-scale habitat modeling of a top marine predator: do prey data improve predictive capacity? | Predators and prey assort themselves relative to each other, the availability of resources and refuges, and the temporal and spatial scale of their interaction. Predictive models of predator distributions often rely on these relationships by incorporating data on environmental variability and prey availability to deter... | 18,839,765 |
Understanding the net effects of pesticides on amphibian trematode infections. | Anthropogenic factors can have simultaneous positive and negative effects on parasite transmission, and thus it is important to quantify their net effects on disease risk. Net effects will be a product of changes in the survival and traits (e.g., susceptibility, infectivity) of both hosts and parasites. In separate lab... | 18,839,768 |
Inhibition of human metapneumovirus replication by small interfering RNA. | Human metapneumovirus (hMPV) is a major respiratory viral pathogen in young children, elderly individuals and immunocompromised patients. Despite its major effects related to bronchiolitis, pneumonia and its potential role in recurrent wheezing episodes, there is still no commercial treatment or vaccine available again... | 18,839,783 |
[Food supplements: modern approaches to quality and safety]. | A normative and legislative base of food supplements turnover in Russia in described in the article. | 18,839,802 |
Primary carcinoma of the fallopian tube and epithelial ovarian carcinoma: a case-control analysis. | To determine whether differences exist in clinicopathologic variables or survival between women with primary carcinoma of the fallopian tube (PCFT) and with epithelial ovarian carcinoma (EOC). University of Iowa Hospitals and Clinics (UIHC) tumor board records were analyzed from January 1, 1991, to April 30, 2001. No c... | 18,839,823 |
Determining dose and endpoints of a controlled-release misoprostol vaginal insert for a phase III trial. | To determine phase III study design using the phase II data for a proprietary controlled-release misoprostol vaginal insert for cervical ripening and labor induction. The reported experiences in 2 phase II trials involving induction of labor in 168 women are discussed. Combining data from 2 phase II studies, we reporte... | 18,839,824 |
The high-risk neonatal hearing screening program in Songklanagarind Hospital. | Determine the prevalence and risk factor of neonatal hearing loss in the high-risk group. A prospective descriptive study, using the criteria of "high-risk" as defined by the Joint Committee of Infant Hearing 1994, American Academy of Pediatrics, 465 newborn in Songklanagarind Hospital were screened with portable otoac... | 18,839,842 |
Closed posteromedial dislocation of the ankle without fracture: a case report. | Ankle dislocation without fracture is an extremely rare injury. Open dislocations were more common in the previous reports. The authors report a case of closed posteromedial dislocation of the ankle in a 24-year-old basketball player. Closed reduction was performed. The ankle was initially immobilized with the short le... | 18,839,857 |
[Treating traumatic ossicular chain disruption with epitympanum approach following tympanotomy]. | To evaluate the therapeutic effects of epitympanum approach tympanotomy in treating traumatic ossicular chain disruption. Ten patients with temporal bone fracture and trauma of ear, whose CT scan of temporal bone showed that Malleoincudal joint irregular shape in the axial view and incudostapedial joint dislocation in ... | 18,839,872 |
[Carbon storage and its allocation in mixed alder-cypress plantations at different age stages]. | The 10-, 15-, 20- and 25-year-old mixed alder (Alnus cremastogyne)-cypress (Cupressus funebris) plantations and the 30-year-old pure cypress plantation succeeded from mixed alder-cypress plantation in the hilly area of central Sichuan Basin were chosen as test objects to study the dynamic changes and allocation pattern... | 18,839,897 |
[Application of 3D visualization software in forest ecosystem management in eastern Liaoning mountainous region]. | By using 3D visualization software WCS 6.0, the virtual forest landscape of Pulepu Town in eastern Liaoning mountainous region was constructed, and the dynamic changes of forests under four different management scenarios, i.e., enclosing undeveloped forest, small area clear-cutting, selective-logging, and two-step prog... | 18,839,900 |
[Evolvement characteristics and coupling relationship of soil organic carbon and total nitrogen in subtropical paddy field ecosystem under different fertilization practices]. | Soil samples were collected from long-term monitoring plots of paddy field ecosystem in Hunan Province to study the evolvement characteristics and coupling relationship of soil organic carbon and total nitrogen under different fertilization practices. The results showed that in 1986-2003, the contents of soil organic c... | 18,839,908 |
[Impacts of rail transit in Shanghai on its urban land use change]. | By using the land use data interpreted with 1:50,000 color-infrared aerial photos of Shanghai collected in 1989 and 2005, and based on Geographic Information System (GIS) techniques, the impacts of urban rail transit (URT) development in Shanghai on its urban land use change was quantitatively analyzed, and a prelimina... | 18,839,916 |
Mechanism of OMP decarboxylation in orotidine 5'-monophosphate decarboxylase. | Despite extensive experimental and theoretical studies, the detailed catalytic mechanism of orotidine 5'-monophosphate decarboxylase (ODCase) remains controversial. In particular simulation studies using high level quantum mechanics have failed to reproduce experimental activation free energy. One common feature of man... | 18,839,943 |
Electrokinetic effect of the bottom surface of a vessel on pearl-chain formation of silica particles. | We have tackled in situ electric conductance measurements under microscopic observations for alignments of silica particles that are induced by ionic polarization of the electrical double layer (EDL) around the particles. Using the in situ conductance measurements, we have presented evidence that electro-osmotic flow a... | 18,839,972 |
Effect of solvent quality on aggregate structures of common surfactants. | Aggregate structures of two model surfactants, AOT and C12E5 are studied in pure solvents D2O, dioxane-d8 (d-diox) and cyclohexane-d12 (C6D12) as well as in formulated D2O/d-diox and d-diox/C6D12 mixtures. As such these solvents and mixtures span a wide and continuous range of polarities. Small-angle neutron scattering... | 18,839,976 |
A simple one-pot preparation of diazoacetoacetate derivatives from aldehydes. | Diazoacetoacetate derivatives can be simply and efficiently prepared from aldehydes in a one-pot process involving initial DBU-promoted "aldol" condensation with ethyl diazoacetate followed by in situ oxidation with IBX. Aryl, alkyl, and unsaturated aldehydes are all viable substrates. | 18,839,995 |
Detecting simulated patterns of lung cancer biomarkers by random network of single-walled carbon nanotubes coated with nonpolymeric organic materials. | An array of chemiresistive random network of single-walled carbon nanotubes coated with nonpolymeric organic materials shows a high potential for diagnosis of lung cancer via breath samples. The sensors array shows excellent discrimination between the volatile organic compounds (VOCs) found in the breath of patients wi... | 18,839,997 |
Treatment options for proliferative lupus nephritis: an update of clinical trial evidence. | Systemic lupus erythematosus involves the kidney in up to 60% of patients, and if untreated, may result in complete loss of kidney function. In this article, we review meta-analyses and clinical trial data on the therapeutic options for proliferative lupus nephritis, and complete a meta-analysis of the use of mycopheno... | 18,840,001 |
Safety of inhaled budesonide: clinical manifestations of systemic corticosteroid-related adverse effects. | Inhaled corticosteroid (ICS) therapy is central to the long-term management of asthma and is extensively used in the management of chronic obstructive pulmonary disease (COPD). While administration via inhalation limits systemic exposure compared with oral or injected corticosteroids and, therefore, the risk of systemi... | 18,840,017 |
Bone quality, quantity and metabolism in terms of dental implantation. | The present paper provides an introduction to regular bone structure in the face area which is considered a precondition of successful implantation. The specific properties of the jaw bones have to be observed in this context. Bone is the largest calcium storage, forms part of the supporting tissue and displays distinc... | 18,840,063 |
Prey behavior, age-dependent vulnerability, and predation rates. | Variation in the temporal pattern of vulnerability can provide important insights into predator-prey relationships and the evolution of antipredator behavior. We illustrate these points with a system that has coyotes (Canis latrans) as a predator and two species of congeneric deer (Odocoileus spp.) as prey. The deer em... | 18,840,071 |
Does isoflurane enhance rhinovirus replication and virus-induced cytokine secretion in airway epithelial cells? | There have been no previous studies regarding the effect of volatile anesthetics on human rhinovirus (RV) infection in airway epithelial cells of patients with an upper respiratory infection (URI). We have therefore evaluated in vitro the effect of isoflurane on RV infection in airway epithelial cells. A549 cells and R... | 18,840,102 |
Xenon alters right ventricular function. | In contrast to other volatile anesthetics, xenon produces less cardiovascular depression with fewer fluctuations of various hemodynamic parameters, but reduces cardiac output (CO) in vivo. Besides an increase in left ventricular afterload and reduction of heart rate, an impairment of the right ventricular function migh... | 18,840,104 |
Genetic analysis, breed assignment and conservation priorities of three native Danish horse breeds. | A genetic analysis was performed on three indigenous Danish horse breeds using 12 microsatellite markers from a standard kit for parental testing. These three breeds are all considered endangered based on their small population sizes. Genetic variation in these three breeds was comparable to other horse breeds in Europ... | 18,840,148 |
New mutations associated with resistance not detected following zidovudine monotherapy in pregnancy when used in accordance with British HIV Association guidelines. | To determine whether mutations conferring drug resistance are detectable after zidovudine monotherapy (ZDVm) in pregnancy, using both standard genotyping and more sensitive cloning assays. Post-delivery samples from women meeting the British HIV Association guidelines criteria for the use of ZDVm in the prevention of m... | 18,840,150 |
Recurrent Kikuchi-Fujimoto disease during pregnancy: report of case evolving into systemic lupus erythematosus and review of published work. | Kikuchi-Fujimoto disease (KFD) is a distinctive, benign type of necrotizing lymphadenitis. KFD is a rare entity, especially during pregnancy. Although first described in Japan, subsequently it has been reported in the West. We communicate herein a case of KFD in African women with bouts during pregnancy. Diagnosis was ... | 18,840,160 |
Cholangiocarcinoma in pregnancy: a case report. | A 32-year-old pregnant woman underwent laparotomy for suspected intra-abdominal mass lesion obstructing the biliary tree. Imaging studies revealed a mass in the fourth segment of the liver. Microscopic examination of the biopsy revealed a cholangiocarcinoma. The clinical course of the malignancy was worsened by her gra... | 18,840,169 |
Concurrent sigmoid volvulus and herniation through broad ligament defect during pregnancy: case report and literature review. | Sigmoid volvulus in pregnancy is a rare complication. The combination of sigmoid volvulus and sigmoid herniation through a broad ligament together with placental abruption in pregnancy is a most unusual obstetrical emergency. We report the case of a previously well 32-year-old Mexican woman who was transferred to our i... | 18,840,175 |
Uterine rupture at scar of prior laparoscopic cornuostomy after vaginal delivery of a full-term healthy infant. | A 30-year-old, gravida 2, para 0 woman who had a history of a laparoscopic cornuostomy for a left interstitial pregnancy was admitted for a vaginal delivery due to labor pains at 40 weeks gestation. A prolonged placental delivery, persistent abdominal pain, and hemorrhagic shock were noted after the delivery of the inf... | 18,840,182 |
Extraovarian pelvic yolk sac tumor: case report and review of published work. | Extraovarian pelvic yolk sac tumors are rare, with only nine cases documented previously in the published work. We report a case of extraovarian pelvic yolk sac tumor occurring synchronously with breast carcinoma. The patient underwent resection of the pelvic tumor and hepatic implant, omentectomy and breast lumpectomy... | 18,840,194 |
Comparing network analysis measures to determine potential epidemic size of highly contagious exotic diseases in fragmented monthly networks of dairy cattle movements in Ontario, Canada. | Adult milking cow movements occurring in monthly periods in 2004-2006 were analysed to compare three network analysis measures to determine the lower and upper bounds of potential maximal epidemic size in an unrestrained epidemic: the out-degree, the infection chain or output domain of a farm, and the size of the stron... | 18,840,200 |
Genetic association studies in nursing practice and scholarship. | To explore the role of genetic association studies in risk assessment for common complex diseases. An introduction to the types of genetic association studies is followed by a discussion of their potential use in risk assessment for age-related macular degeneration and type 2 diabetes mellitus. The benefits and limitat... | 18,840,203 |
Responders and nonresponders to a walking intervention for sedentary women. | Increasing evidence has indicated that people might be differentially influenced by intervention programs. The purpose of this secondary analysis was to identify groups of women who responded differently to a walking intervention. Data used in this secondary analysis were collected in a longitudinal study of a counseli... | 18,840,205 |
Outcome analysis of a research-based didactic model for education to promote culturally competent nursing care in Sweden--a questionnaire study. | To describe and analyse to what extent the goals of the education in promoting culturally competent nursing care have been achieved from a student perspective. As Sweden has transformed into a multicultural society over the past 50 years, there is a need to specify, at all levels of the nursing programme, transcultural... | 18,840,218 |
'Nobody likes a back bore'--exploring lay perspectives of chronic pain: revealing the hidden voices of nonservice users. | Chronic pain is pain that persists beyond 12 weeks or that lasts beyond the expected duration of healing. The chronic pain sufferer also often experiences associated anxiety, depression and stress. An exploratory qualitative approach was adopted by the authors to explore what it is like to live with chronic pain from a... | 18,840,222 |
Radiographers' areas of professional competence related to good nursing care. | Radiographers' ability and competence is a matter of vital importance for patients. Nursing care is an integral part of the radiographer's work. The demand for high competence in clinical activities has increased in diagnostic radiology and has had an impact on the development of the profession. The aim was to describe... | 18,840,224 |
Rhegmatogenous retinal detachment after a lower extremity dog bite: a case report. | The occurrence of endogenous endophthalmitis is well known in the settings of bacteremia or candidemia, although its association with rhegmatogenous retinal detachment remains unclear. We present a case of rhegmatogenous retinal detachment in a 39 year old man who presented with acute vision loss six weeks after a lowe... | 18,840,259 |
Determination of the mimic epitope of the M-like protein adhesin in swine Streptococcus equi subsp. zooepidemicus. | The M-like protein, also known as SzP, is expressed on the surface of Streptococcus equi subsp. zooepidemicus (S. zooepidemicus). Previous studies demonstrated that SzP is similar to M protein of group A Streptococcus in the structure and characteristics of antiphagocytosis. The M protein is an adhesin that can bind to... | 18,840,263 |
Bayesian modeling of recombination events in bacterial populations. | We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fairly closely related species. The currently available methods for recombination detection capable of probabilistic characterization of uncertainty have a... | 18,840,286 |
Family caregiver quality of life in multiple sclerosis among Kuwaitis: a controlled study. | Research interest in the quality of life (QOL) of persons with multiple sclerosis (MS) has been spurred by the need to broaden outcome measures. Far less of this interest has been directed at the family caregivers, who bear most of the burden of care. The objectives of the study were: First, to compare the subjective Q... | 18,840,287 |
HIV testing and care in Canadian Aboriginal youth: a community based mixed methods study. | HIV infection is a serious concern in the Canadian Aboriginal population, particularly among youth; however, there is limited attention to this issue in research literature. The purpose of this national study was to explore HIV testing and care decisions of Canadian Aboriginal youth. A community-based mixed-method desi... | 18,840,292 |
A genome-wide scan for quantitative trait loci affecting limb bone lengths and areal bone mineral density of the distal femur in a White Duroc x Erhualian F2 population. | Limb bone lengths and bone mineral density (BMD) have been used to assess the bone growth and the risk of bone fractures in pigs, respectively. It has been suggested that limb bone lengths and BMD are under genetic control. However, the knowledge about the genetic basis of the limb bone lengths and mineralisatinon is l... | 18,840,302 |
Mendelian inheritance of t haplotypes in house mouse ( Mus musculus domesticus) field populations. | Alleles of many genes in the house mouse (Mus musculus domesticus) t complex influence embryonic development, male transmission ratio, male fertility and other traits. Homozygous t lethal alleles cause prenatal lethality, whereas male t semilethal homozygotes and males heterozygous for two complementing t lethal haplot... | 18,840,307 |
Ultrasonographic measurement of tendon displacement caused by active force generation in the psoas major muscle. | The purpose of this study was to examine the validity of using ultrasonography for detecting the force generated by the psoas major muscle, a muscle positioned in the deep trunk. We measured the displacement of central tendon on B-mode ultrasound images of two different longitudinal sections of the muscle during passiv... | 18,840,323 |
Bioavailability of two sublingual formulations of ketorolac tromethamine 30 mg: a randomized, open-label, single-dose, two-period crossover comparison in healthy Mexican adult volunteers. | Ketorolac tromethamine (ie, ketorolac) is an NSAID that appears to have several mechanisms of action, including inhibition of prostaglandin synthesis, modulatory effect on opioid receptors, and nitric oxide synthesis. Ketorolac is used in the treatment of pain. There are various generic formulations of sublingual ketor... | 18,840,372 |
Collagen XVIII and corneal reinnervation following keratectomy. | The significance of collagen XVIII in the regulation of corneal reinnervation remains largely unknown. We used whole-mount immunoconfocal microscopy to localize collagen XVIII to the nerve basement membrane of wild-type (WT) mouse corneas. Transmission electron microscopy showed corneal nerve disorganization in collage... | 18,840,438 |
Capture of cell culture-derived influenza virus by lectins: strain independent, but host cell dependent. | Strategies to control influenza outbreaks are focused mainly on prophylactic vaccination. Human influenza vaccines are trivalent blends of different virus subtypes. Therefore and due to frequent antigenic drifts, strain independent manufacturing processes are required for vaccine production. This study verifies the str... | 18,840,469 |
Sex differences in skilled movement in response to restraint stress and recovery from stress. | Sex differences exist in skilled movement, and skilled motor performance is also influenced by stress. As shown for cognitive function, the effects of stress are usually characterized by considerable sexual dimorphism. The purpose of this study was to investigate sex differences in skilled motor function in response to... | 18,840,472 |
Attentional demands for demonstrating deficits following intrabasalis infusions of 192 IgG-saporin. | Previous research has shown that basal forebrain cholinergic inputs to the cerebral cortex are necessary for attentional processing. However, the key components of attention-demanding tasks for demonstrating deficits following loss of basal forebrain corticopetal cholinergic neurons are unclear. In the present experime... | 18,840,475 |
Sustained depolarizing shift of the GABA reversal potential by glutamate receptor activation in hippocampal neurons. | The inhibitory action of GABA is a consequence of a relatively hyperpolarized Cl(-) reversal potential (E(Cl)), which results from the activity of K(+)-Cl(-) cotransporter (KCC2). In this study we investigated the effects of glutamate and glutamatergic synaptic activity on E(Cl). In dissociated culture of mature hippoc... | 18,840,481 |
Hydrogel nanoparticles in drug delivery. | Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system (e.g., hydrophilicity and extremely high water content) with a nanoparticle (e.g., very sma... | 18,840,488 |
Active targeting schemes for nanoparticle systems in cancer therapeutics. | The objective of this review is to outline current major cancer targets for nanoparticle systems and give insight into the direction of the field. The major targeting strategies that have been used for the delivery of therapeutic or imaging agents to cancer have been broken into three sections. These sections are angio... | 18,840,489 |
Increases in energy, protein and fat intake following the addition of sauce to an older person's meal. | Energy intake in 15-20% of the UK older population is currently thought to be inadequate for health. Based on the suggestion that increases in food pleasantness and familiarity can increase intake, this study investigated the impact of the addition of sauce to an older person's meal on subsequent intake. Twenty-eight o... | 18,840,490 |
Focal distortion of the nuclear envelope by huntingtin aggregates revealed by lamin immunostaining. | Huntington's disease is an autosomal dominant neurodegenerative disorder caused by the expansion of a polyglutamine repeat tract in the huntingtin protein. Polyglutamine-expanded huntingtin forms intranuclear as well as perinuclear inclusion bodies. Perinuclear aggregates formed by polyglutamine-expanded proteins are a... | 18,840,504 |
Effect of nitric oxide on auditory cortical neurons of aged rats. | Age-related changes in the effects of nitric oxide (NO) on neurons of the auditory cortex have not been determined. We therefore evaluated the anatomical changes and neurophysiological characteristics of these neurons in rats as a function of age. The numbers of cresyl violet stained cells, the numbers and areas of NAD... | 18,840,505 |
(-)-Veranigrine, a new steroidal alkaloid from Veratrum nigrum L. | A new steroidal alkaloid, (-)-veranigrine (1) was isolated from the roots and rhizomes of Veratrum nigrum L. By means of spectroscopic methods its structure was established as (20S, 25S)-iminocholesta-5,22(N)-diene-1beta,3beta-diol. | 18,840,510 |
Overexpression of a novel endogenous NADH kinase in Aspergillus nidulans enhances growth. | The complete genome sequence of the filamentous fungi Aspergillus nidulans has paved the way for fundamental research on this industrially important species. To the best of our knowledge, this is the first time a gene encoding for ATP-dependent NADH kinase (ATP:NADH 2'-phosphotransferase, EC 2.7.1.86) has been identifi... | 18,840,540 |
Physiological noise versus white noise to drive a variable ventilator in a porcine model of lung injury. | Variable ventilation is superior to control mode ventilation in a number of circumstances. The nature of the breathing file used to deliver the variable rate and tidal volume has not been formally examined. We compared two different noise files in a randomized prospective trial of variable ventilation. Pigs were anesth... | 18,840,587 |
Cardioprotective effects of propofol in isolated ischemia-reperfused guinea pig hearts: role of KATP channels and GSK-3beta. | Propofol exerts cardioprotective effects, but the involved mechanisms remain obscure. The present study examines the cardioprotective effects of propofol and its role in cardiac function, including its effect on K(ATP) channel opening and the inhibition of GSK-3beta activity in ischemia-reperfused hearts. Ischemia-repe... | 18,840,589 |
Fatal SIR diseases and rational exemption to vaccination. | A challenge to disease control in modern societies is the spread of rational exemption to vaccination as a consequence of the rational comparison between the steadily declining risk of infection and the risk of side effects from the vaccine. Here, we consider rational exemption in an susceptible-infectious-removed (SIR... | 18,840,601 |
Structural insight into the kinetics and DeltaCp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP). | In a previous study, we examined thermodynamic parameters for 20 alanine mutants in beta-lactamase inhibitory protein (BLIP) for binding to TEM-1 beta-lactamase. Here we have determined the structures of two thermodynamically distinctive complexes of BLIP mutants with TEM-1 beta-lactamase. The complex BLIP Y51A-TEM-1 i... | 18,840,610 |
Effects of antithrombin III in patients with disseminated intravascular coagulation diagnosed by newly developed diagnostic criteria for critical illness. | A study was conducted to test the hypotheses that antithrombin III (antithrombin) improves disseminated intravascular coagulation (DIC) when applied to DIC patients diagnosed by sensitive criteria and that the administration of high-dose antithrombin is a beneficial treatment for DIC. Twenty-three DIC patients diagnose... | 18,840,625 |
Oxidative stress and total antioxidant capacity in diabetic and nondiabetic acute ischemic stroke patients. | Free radical formation is the pivotal mechanism of neuronal injury of ischemic and reperfused brain tissue. In healthy individuals, antioxidant activity counterbalances free radical production, but in the case of ischemia, the balance between reactive oxygen species and antioxidant activity is shifted toward free radic... | 18,840,626 |
The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface. | There are at least 24 missense, nonconservative mutations found in the ACTH receptor [melanocortin 2 receptor (MC2R)] that have been associated with the autosomal recessive disease familial glucocorticoid deficiency (FGD) type 1. The characterization of these mutations has been hindered by difficulties in establishing ... | 18,840,636 |
A Dictyostelium homologue of the metazoan Cbl proteins regulates STAT signalling. | Cbl proteins downregulate metazoan signalling pathways by ubiquitylating receptor tyrosine kinases, thereby targeting them for degradation. They contain a phosphotyrosine-binding region, comprising an EF-hand and an SH2 domain, linked to an E3 ubiquitin-ligase domain. CblA, a Dictyostelium homologue of the Cbl proteins... | 18,840,649 |
Blood flow and metabolic regulation in seal muscle during apnea. | In order to examine myoglobin (Mb) function and metabolic responses of seal muscle during progressive ischemia and hypoxemia, Mb saturation and high-energy phosphate levels were monitored with NMR spectroscopy during sleep apnea in elephant seals (Mirounga angustirostris). Muscle blood flow (MBF) was measured with lase... | 18,840,667 |
Role of RHOB in the antiproliferative effect of glucocorticoid receptor on macrophage RAW264.7 cells. | Although glucocorticoid (GC) has been reported to inhibit macrophage killing activity and cytokine production in response to proinflammatory stimuli, the effect of GC on macrophage proliferation is controversial. In our previous study, we found that inhibition of glucocorticoid receptor (GR) expression in murine macrop... | 18,840,672 |
Emergent name-writing abilities of preschool-age children with language impairment. | The 2 studies reported in this manuscript collectively address 3 aims: (a) to characterize the name-writing abilities of preschool-age children with language impairment (LI), (b) to identify those emergent literacy skills that are concurrently associated with name-writing abilities, and (c) to compare the name-writing ... | 18,840,675 |
The diagnostic accuracy and construct validity of the structured photographic expressive language test--preschool: second edition. | In order to support evidence-based practice, this study served to evaluate the diagnostic accuracy, convergent validity, and divergent validity of the Structured Photographic Expressive Language Test-Preschool: Second Edition (SPELT-P2; J. Dawson, J. A. Eyer, J. Fonkalsrud, 2005) in order to determine whether it can be... | 18,840,676 |
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. | Aire induces ectopic expression of peripheral tissue antigens (PTAs) in thymic medullary epithelial cells, which promotes immunological tolerance. Beginning with a broad screen of histone peptides, we demonstrate that the mechanism by which this single factor controls the transcription of thousands of genes involves re... | 18,840,680 |
Mechanism of and exquisite selectivity for O-O bond formation by the heme-dependent chlorite dismutase. | Chlorite dismutase (Cld) is a heme b-dependent, O-O bond forming enzyme that transforms toxic chlorite (ClO(2)(-)) into innocuous chloride and molecular oxygen. The mechanism and specificity of the reaction with chlorite and alternate oxidants were investigated. Chlorite is the sole source of dioxygen as determined by ... | 18,840,691 |
Cell adhesion through alphaV-containing integrins is required for efficient HIV-1 infection in macrophages. | Monocytes and macrophages are an important reservoir of human immunodeficiency virus (HIV) and may represent the largest reservoir of this virus in tissues. Differentiation of monocytes into macrophages leads to cell attachment and susceptibility to infection and replication of HIV. Among other cell-surface molecules, ... | 18,840,709 |
Dracunculiasis eradication: neglected no longer. | This report summarizes the status of the global Dracunculiasis Eradication Program as of early 2008. By the end of 2007, dracunculiasis (Guinea worm disease) transmission had been eliminated from 15 of the 20 countries where the disease was endemic in 1986, only 9,585 cases were reported worldwide, and 2,016 villages s... | 18,840,732 |
Presence of Enterocytozoon bieneusi associated with intestinal coccidia in patients with chronic diarrhea visiting an HIV center in Haiti. | This study investigated the presence of Enterocytozoon bieneusi as a possible cause of chronic diarrhea in Haitian patients attending the GHESKIO AIDS clinic in Port-au-Prince, Haiti. Coccidian oocysts were found by polymerase chain reaction (PCR) in the stools of 58/74 patients with chronic diarrhea and included the f... | 18,840,748 |
Association of nutritional status with the response to infection with Leishmania chagasi. | Outcomes of infection with Leishmania chagasi range from self-resolving infection to visceral leishmaniasis (VL). Risk factors determining development of disease are not totally understood, but probably include environmental influences and host genetics. We assessed whether nutrition influenced the outcome of Leishmani... | 18,840,750 |
Neuronal pentraxins modulate cocaine-induced neuroadaptations. | Neuronal pentraxins (NPs) function in the extracellular matrix to bind alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Three NPs have been described, neuronal activity-regulated pentraxin (Narp), which is regulated as an immediate early gene, NP1, and neuronal pentraxin receptor (NPR). Narp a... | 18,840,757 |
Sperm polymorphism within the sea urchin Strongylocentrotus droebachiensis: divergence between Pacific and Atlantic oceans. | The rapid evolution of traits related to fertilization such as sperm morphology may be pivotal in the evolution of reproductive barriers and speciation. The sea urchin Strongylocentrotus droebachiensis has a circumarctic distribution and shows substantial genetic subdivision between northeastern Atlantic populations an... | 18,840,772 |
Effect of temperature on the settlement choice and photophysiology of larvae from the reef coral Stylophora pistillata. | To better understand the consequences of climate change for scleractinian corals, Stylophora pistillata was used to test the effects of temperature on the settlement and physiology of coral larvae. Freshly released larvae were exposed to temperatures of 23 degrees C, 25 degrees C (ambient), and 29 degrees C at light in... | 18,840,774 |
Access site management after peripheral percutaneous transluminal procedures: Neptune pad compared with conventional manual compression. | To investigate the safety and efficacy of the procoagulant wound dressing Neptune Pad (Biotronik, Berlin, Germany) compared with those of conventional manual compression for access site management after peripheral percutaneous interventions. The study was approved by the institutional ethics committee, and all patients... | 18,840,791 |
Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. | Talking about death can be difficult. Without evidence that end-of-life discussions improve patient outcomes, physicians must balance their desire to honor patient autonomy against a concern of inflicting psychological harm. To determine whether end-of-life discussions with physicians are associated with fewer aggressi... | 18,840,840 |
Successful treatment of patients with lipoprotein glomerulopathy by protein A immunoadsorption: a pilot study. | No established therapy is available for patients with lipoprotein glomerulopathy (LPG). Protein A immunoadsorption has been proved to be effective in reducing proteinuria in patients with nephrotic syndrome. In this uncontrolled pilot study, we investigated the efficiency of immunoadsorption onto staphylococcal protein... | 18,840,890 |
Characterization of a novel model for investigation of radiocontrast nephrotoxicity. | Radiocontrast agents are one of the most common causes of acute renal failure in the world. These agents are required for both diagnostic and therapeutic modalities of medical intervention, including computed tomography (CT), angiography and cardiac catheterization. Publications over the past 40 years support three pot... | 18,840,895 |
Evaluation of a point-of-care transcutaneous bilirubinometer in Chinese neonates at an accident and emergency department. | To evaluate the use of a point-of-care transcutaneous bilirubinometer, JM-103 Minolta, for estimation of the serum bilirubin level in the management of neonatal jaundice in term or near-term Chinese neonates. Prospective correlation study. Accident and Emergency Department of a regional hospital in Hong Kong. All term ... | 18,840,905 |
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