title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Magnetic resonance imaging techniques: fMRI, DWI, and PWI. | Magnetic resonance imaging (MRI) is a noninvasive technique which can acquire important quantitative and anatomical information from an individual in any plane or volume at comparatively high resolution. Over the past several years, developments in scanner hardware and software have enabled the acquisition of fast MRI ... | 18,843,569 |
Neuroimaging in ischemia and infarction. | The authors provide an overview of current clinical neuroimaging techniques for acute ischemic stroke. The pathophysiology of ischemic stroke is briefly reviewed, especially as it pertains to cerebral blood flow. There are three important goals that must be met in the imaging of an acute ischemic stroke: (1) to quantit... | 18,843,573 |
Neuroimaging of toxic and metabolic disorders. | Imaging of the brain, magnetic resonance imaging (MRI) in particular, is a key adjunctive tool in the diagnosis and management of toxic-metabolic disorders such as alcoholism, mitochondrial encephalopathies, disorders of iron or copper metabolism, exposure to carbon monoxide, radiotherapy, immunosuppressive agents, tol... | 18,843,577 |
Periventricular leukomalacia in premature infants in mainland China. | Periventricular leukomalacia (PVL) in premature infants is a major cause of mortality and disability. However, while China is the largest developing country, there is an absence of data concerning PVL. This study was carried out in order to explore the incidence rate and analyze the high-risk factors of PVL in prematur... | 18,843,588 |
Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery. | Peripheral arterial disease (PAD) may cause occlusions (blockages) in the main arteries of lower limbs. One treatment option is bypass surgery using autologous (the patient's own tissue) vein graft or artificial graft. A number of factors influence occlusion rates, including the material used. To prevent graft occlusio... | 18,843,613 |
Oestrogens and progestins for preventing and treating postpartum depression. | Postpartum depression is a common complication of childbirth, affecting approximately 13% of women. A hormonal aetiology has long been hypothesised due to the sudden and substantial fluctuations in concentrations of steroid hormones associated with pregnancy and the immediate postpartum period. There is also convincing... | 18,843,619 |
Massage for low-back pain. | Low-back pain is one of the most common and costly musculoskeletal problems in modern society. Proponents of massage therapy claim it can minimize pain and disability, and speed return to normal function. To assess the effects of massage therapy for non-specific low-back pain. We searched MEDLINE, EMBASE, CINAHL from t... | 18,843,627 |
Nutrition support for bone marrow transplant patients. | This is an update of the original Cochrane review published in Issue 2, 2002. Bone marrow transplantation involves administration of toxic chemotherapy and infusion of marrow cells. After treatment, patients can develop poor appetite, mucositis and gastrointestinal failure, leading to malnutrition. To prevent this, par... | 18,843,634 |
Fluticasone versus placebo for chronic asthma in adults and children. | Inhaled fluticasone propionate (FP) is a relatively new inhaled corticosteroid for the treatment of asthma. To assess efficacy and safety outcomes in studies that compared FP to placebo for treatment of chronic asthma. We searched the Cochrane Airways Group Specialised Register (January 2008), reference lists of articl... | 18,843,640 |
Antibiotics for the prophylaxis of bacterial endocarditis in dentistry. | Infective endocarditis is a severe infection arising in the lining of the heart with a high mortality rate.Many dental procedures cause bacteraemia and it was believed that this may lead to bacterial endocarditis (BE) in a few people. Guidelines in many countries have recommended that prior to invasive dental procedure... | 18,843,649 |
Combination contraceptives: effects on weight. | Weight gain is often considered a side effect of combination hormonal contraceptives, and many women and clinicians believe that an association exists. Concern about weight gain can limit the use of this highly effective method of contraception by deterring the initiation of its use and causing early discontinuation am... | 18,843,652 |
Surgical versus conservative management for odontoid fractures. | Fractures of the odontoid process of the second cervical vertebra can result in instability, neurological damage and death. Treatment includes conservative management (external immobilisation devices) or surgical treatment (internal fixation by posterior fusion or anterior screw fixation). To compare surgical with cons... | 18,843,678 |
Interventions to improve outpatient referrals from primary care to secondary care. | The primary care specialist interface is a key organisational feature of many health care systems. Patients are referred to specialist care when investigation or therapeutic options are exhausted in primary care and more specialised care is needed. Referral has considerable implications for patients, the health care sy... | 18,843,691 |
Dengzhanhua preparations for acute cerebral infarction. | Dengzhanhua preparations are widely used in China. Many controlled trials have been undertaken to investigate the efficacy of dengzhanhua preparations in the treatment of acute cerebral infarction. To assess whether dengzhanhua preparations are effective and safe at improving outcomes in patients with acute cerebral in... | 18,843,694 |
Antimotility agents for chronic diarrhoea in people with HIV/AIDS. | AIDS-related diarrhoea is a common cause of morbidity and mortality in HIV positive individuals, especially in the sub-Saharan Africa where 70% of deaths from HIV occur. It often compromises quality of life both in those receiving antiretroviral therapy (ART) and the ART naive. Empirical antidiarrhoeal treatment may be... | 18,843,696 |
Nutritional supplements for people being treated for active tuberculosis. | Tuberculosis is a serious infection affecting mainly the lungs. It may contribute to nutritional deficiencies which in turn may delay recovery by depressing immune functions. Nutritional supplements might therefore promote recovery in people being treated for tuberculosis. To assess the provision of oral nutritional su... | 18,843,702 |
Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers. | Staphylococcus aureus (S. aureus) is the leading nosocomial (hospital acquired) pathogen in hospitals throughout the world. Traditionally, control of S. aureus has been focused on preventing cross-infection between patients, however, it has been shown repeatedly that a large proportion of nosocomial S. aureus infection... | 18,843,708 |
Touch therapies for pain relief in adults. | Pain is a global public health problem affecting the lives of large numbers of patients and their families. Touch therapies (Healing Touch (HT), Therapeutic Touch (TT) and Reiki) have been found to relieve pain, but some reviews have suggested there is insufficient evidence to support their use. To evaluate the effecti... | 18,843,720 |
Interventions (other than pharmacological, psychosocial or psychological) for treating antenatal depression. | Although pregnancy was once thought of as a time of emotional well-being for many women, conferring 'protection' against psychiatric disorders, a recent meta-analysis of 21 studies suggests the mean prevalence rate for depression across the antenatal period is 10.7%, ranging from 7.4% in the first trimester to a high o... | 18,843,730 |
Early versus delayed laparoscopic cholecystectomy for biliary colic. | Biliary colic is one of the commonest indications for laparoscopic cholecystectomy. Laparoscopic cholecystectomy involves several months of waiting if performed electively. However, patients can develop life-threatening complications during this waiting period. To assess the benefits and harms of early versus delayed l... | 18,843,746 |
Organising health care services for persons with an intellectual disability. | When compared to the general population, persons with an intellectual disability have lower life expectancy, higher morbidity, higher rates of unmet health needs, and more difficulty finding and getting health care. Organisational interventions are used to reconfigure the structure or delivery of health care services a... | 18,843,752 |
Electrocardiographic findings in psoriatic arthritis: a case-controlled study. | We assessed cardiac conduction properties in patients with psoriatic arthritis (PsA). Electrocardiogram (ECG) scans of 92 patients with PsA were compared to 92 age and sex matched nonpsoriatic, nonarthritic patients from general practice serving as controls. PR interval was found to be significantly longer in the PsA g... | 18,843,776 |
Associations between FCGR3A polymorphisms and susceptibility to rheumatoid arthritis: a metaanalysis. | .To investigate whether the Fcgamma receptor (FCGR) polymorphism confers susceptibility to rheumatoid arthritis (RA). We conducted metaanalyses on the associations between FCGR polymorphisms and RA susceptibility as determined using (1) allele contrast, (2) recessive models, (3) dominant models, and (4) contrast of hom... | 18,843,786 |
Sleep-waking cycle in the cerveau isolé cat. | The experiments were performed on ten chronic low cerveau isolé cats: in eight cats the brain stem transection was prepontine and in two cats, intercollicular. The preparations survived from 24 to 3 days. During 24-36 hr sessions the ECoG activity was continuously recorded, and the ocular and ECoG components of the ori... | 18,843,820 |
Device diagnostics for heart failure: identifying eligible patients. | The prevalence of heart failure has increased by 500% over the past 30 years, creating a significant burden on the health care system. Traditional means of detecting worsening heart failure, such as subjective assessment, symptoms, and physical examination, lack sensitivity and specificity. Many nurses who manage heart... | 18,843,830 |
Disability associated with comorbid anxiety disorders in women with chronic physical illness in Ontario, Canada. | Anxiety disorders are more prevalent in individuals with chronic physical illness compared to individuals with no such illness, and about twice as prevalent in women as in men. This study used data collected in the 2005 Canadian Community Health Survey (21,198 women and 20,478 men) to examine factors associated with co... | 18,843,837 |
Women's health policies associated with obesity, diabetes, high blood pressure, and smoking: a follow-up on the women's health report card. | This study sought to elucidate associations between state-level policies related to women's health and state prevalence of obesity, smoking, high blood pressure, and diabetes among women. Using data from national sources compiled for Making the Grade on Women's Health: A National and State-by-State Report Card, state p... | 18,843,842 |
[Causes of climatic changes and their consequences on human health]. | Environmental disasters are common phenomena caused by human factors. Disaster episodes may be the result of climatic changes such as global warming, which can lead to floods or drought. Greenhouse gases, and especially the ozone, represent a special problem. Atmospheric pollutions are the result of fire, storm dusts, ... | 18,843,850 |
Evaluation of direct immunofluorescence test for diagnosis of upper respiratory tract infection by Chlamydia pneumoniae. | Chlamydia pneumoniae causes a variety of respiratory infections and is involved in cardiovascular diseases. Diagnosis of C. pneumoniae infection currently relies on antibody detection by microimmunofluorescence (MIF), which has limited use, and is the retrospective diagnosis for acute infection. Find an effective early... | 18,843,873 |
Geographical variation of mortality in Thailand. | To examine geographical variation of mortality in Thailand. Descriptive ecological study using the national vital registration data in 2000, age-specific mortality rate and cause-specific standardized mortality ratio (SMR) were presented at district geographic level. Overall mortality was highly concentrated in the mid... | 18,843,878 |
Biotypes, genotypes and ketoconazole susceptibility of Candida albicans isolates from a group of Thai AIDS patients. | A total of eighty-seven Candida albicans isolates from a group of Thai AIDS patients were characterized for phenotypic and genotypic profiles and antifungal susceptibility to ketoconazole. Phenotyping of the isolates was carried out by a biotyping method based on the enzyme profiles, carbohydrate assimilation patterns ... | 18,843,897 |
[Surgical aspects of primary tuberculosis in children: clinical presentation and indications for surgical treatment]. | During the last years a trend of increasing the cases with primary pulmonary tuberculosis (PPT) in our country is observed. The aim of this study is to analyze retrospectively the pediatric cases with PPT and to determinate the specific clinical features as well the indications for surgery. For a period of six years (2... | 18,843,903 |
Disparities in preventive care by body mass index categories among women. | The present analyses examined the relationship of body mass index (BMI) categories to receiving age-appropriate preventive services among women. Data from the Medical Expenditure Panel Survey (2003, N = 10,954) were analyzed using multiple logistic regressions. Outcomes were: age-appropriate Pap-test, mammography, colo... | 18,843,937 |
Frequent search for sense by long-term breast cancer survivors associated with reduced HRQOL. | This study examined breast cancer survivors' reports of continuing efforts to make sense of their breast cancer experience and associations of such efforts with post-traumatic stress symptomology (PTSS) and long-term health related quality of life (HRQOL). A cross-sectional survey was conducted with 636 women in 2002-2... | 18,843,938 |
[An experiment of 125I radioactive pancreatic duct stents implanted in the pancreatic ducts of pigs]. | To evaluate the feasibility and safety of radioactive pancreatic duct stents implanted in the pancreatic ducts of pigs by endoscopy. Different doses of 125I radioactive pancreatic duct stents were implanted in the pancreatic ducts of pigs by endoscopy. Blood tests were conducted before and after implantation. 14, 30 an... | 18,843,954 |
[Expression of relaxin receptor in placental tissues of normal pregnancy and pre-eclampsia]. | To study the location and level of relaxin receptor in placenta tissues of pre-eclampsia and normal pregnancy, and the relationship of relaxin receptor with pre-eclampsia. Twenty-six placenta tissue samples from pregnant women with severe preeclampsia (study group), and 20 samples from normal pregnancies (control group... | 18,843,967 |
[Intermediate and long term clinical effects of uterine arterial embolization with sodium alginate microspheres in treatment of diffuse adenomyosis]. | To study intermediate and long term efficacy of uterine arterial embolization (UAE) with sodium alginate microspheres (KMG) at diameters 500-00 microm in treatment of diffuse adenomyosis. Totally 40 patients with standard diffuse adenomyosis were enrolled and treated with UAE. KMG at diameters 500-700 microm for vascul... | 18,843,968 |
[Study of brain-derived neurotrophic factor activating TrkB signaling cascades in the pathogenesis of multiple myeloma]. | To explore the significance of abnormal expression of brain-derived neurotrophic factor (BDNF)/TrkB in the development and evolution of multiple myeloma (MM) and the involved signaling pathways. The effect of BDNF on the cell viability of human myeloma cell line (HMCL) (RPMI8226, U266, KM3) was determined by trypan blu... | 18,843,977 |
[Study on glutamate substrate-induced regulation on expression of glutamate transporter GLAST of mouse retinal Müller cells]. | To study glutamate substrate-induced regulation on the expression of glutamate transporter L-glutamate/L-aspartate transporter (GLAST) of retinal Müller cells (RMCs) in mice. Activity of GLAST was measured through L-3 H-glutamate uptake detection. The expression of GLAST protein in lysates cells was studied using Weste... | 18,844,020 |
[Non-thoracoscopic Nuss procedure for correction operation of pectus excavatum ]. | To review the experience in correction operation of pectus excavatum with non-thoracoscopic Nuss procedure. From September 2005 to August 2007, 108 patients with pectus excavatum were surgically corrected by non-thoracoscopic Nuss procedure. There were 91 male patients and 17 female patients. The age was from 2 years a... | 18,844,047 |
[Outcome of malignant melanoma in gastrointestinal tract: clinical analysis of 70 cases]. | To investigate the diagnosis and treatments of malignant melanoma in gastrointestinal tract. The clinical data of 70 cases of malignant melanoma in gastrointestinal tract treated between July 1965 and June 2007 were collected and analyzed. There were 27 male and 43 female patients in this group with a median age of 53 ... | 18,844,049 |
[The effect of portal blood stasis on lung and renal injury induced by hepatic ischemia reperfusion in a rabbit model]. | To investigate the effect and mechanism of portal blood stasis on lung and renal injury induced by hepatic ischemia reperfusion. A rabbit hepatic ischemia reperfusion injury model was established by hepatic portal occlusion and in situ hypothermic irrigation for 30 min. Twenty-four New Zealand white rabbits were employ... | 18,844,057 |
[Promoter methylation status of PTEN gene and the effect of induced demethylation in leukemia cell lines]. | To explore the mechanism of PTEN gene expression silence in leukemia cells, and the effect of induced PTEN gene expression in leukemia cells. Methylation status of PTEN in leukemic cell lines, including HL-60, Nalm-6, NB4, U937, Raji, K562 and KG-1a was assessed by methylation specific PCR (MSP). The cell lines were th... | 18,844,062 |
[The clinical and laboratory features of 263 cases of chronic lymphocytic leukemia]. | To analyze the clinical and laboratory features of chronic lymphocytic leukemia (CLL). Retrospective investigation of 263 patients with CLL in our hospital between Feb. 2000 and Jan. 2007. The median age was 60 years with male/female ratio of 2.17 : 1. Patients who were asymptomatic at diagnosis (35.4%) had low Rai gra... | 18,844,065 |
[Identification of interaction partners and function analysis of new splicing product of human LMO2 gene]. | To identify the interaction partners of a new splicing product of LMO2 gene (LMO2-C), and study its function in K562 cells. Maltose binding protein (MBP) pull down and mammalian two-hybrid assay (MTHA) were used to identify the interaction partners of LMO2-C in K562 cells. Semiquantitative RT-PCR was used to detect the... | 18,844,071 |
Health information outreach: experiences from the University of Zambia Medical Library. | Access to health information for health workers in Zambia is limited and inadequate, especially to those health workers that are not affiliated with institutions such as the University of Zambia. In order to meet their information needs, it is important to devise and implement appropriate health information access meth... | 18,844,090 |
[Association of stroke and different combinations of metabolic syndrome components in Chinese adults]. | To analyze the association of stroke and metabolic syndrome as well as its component combinations in Chinese adults. Logistic regression was used to analyze the data, including anthropometric measurement, fasting plasma glucose (FPG), blood lipids, and histories of smoking, drinking, and anamnesis, of 47,414 subjects, ... | 18,844,096 |
[Influence of recombinant transforming growth factor-beta3 on collagen synthesis and deposition: experiment with rat cell model of liver fibrosis]. | To investigate the influence of recombinant transforming growth factor-beta3 (TGF-beta3) on collagen synthesis and deposition. Plasmids pcDNA3.1 (+)-TGF-beta3 and pcDNA3.1 (+)-TGF-beta1 were constructed. Rat hepatic stellate cells (HSCs) of the strain HSC-T6 were cultured as cell model of fibrosis and divided into 4 gr... | 18,844,103 |
[Effects of sulfur dioxide, on the proliferation and apoptosis of aorta smooth muscle cells in hypertension: experiments with rats]. | To explore the effects of sulfur dioxide (SO2) on the proliferation and apoptosis of aorta smooth muscle cells in hypertension rats and possible mechanism thereof. Sixteen 4-week-old male spontaneously hypertensive rats (SHRs) were randomly divided into 2 equal groups: control and Na2SO3/NaHSO3 (a SO2 donor)-treated gr... | 18,844,104 |
[Hydrological and edaphic structure of an oyster-farming site: Duna Blanca (Bay of Dakhla, south Morocco)]. | Morocco shelters lagoons, estuaries and bays along its paralic coasts which are among the most productive in the world. The Bay of Dakhla is the longest and the most important site in Morocco due to its halieutic richness. In fact, this bay is an ecosystem with great potential in terms of aquaculture, mainly shellfish ... | 18,844,130 |
[Frequency up-conversion properties of Er3+ /Yb3+ co-doped zinc oxide powders]. | Er3+ /Yb3+ co-doped ZnO powders were prepared by the high temperature sintering method with starting composition of (mol%) 95ZnF2-4. 8Yb2 O3-0. 2Er2 O3. Microstructure analysis by X-ray diffraction (XRD) showed that the sample consists of two phases, i. e. ZnO and YbF3, which verified that the ZnF2 was oxidized during ... | 18,844,142 |
[Application of near-infrared spectroscopy in golf turfgrass management]. | The management of golf course is different from other turfs. Its particularity lies in its higher and more precise requirement during maintenance compare with other turfs. In case something happened to turf of golf course, more effective and higher speed detecting and resolution are required. Only the data about turf g... | 18,844,156 |
[Applications of near-infrared spectroscopy to analysis of traditional Chinese herbal medicine]. | Analysis of traditional Chinese herbal medicine is of great importance to its quality control Conventional analysis methods can not meet the requirement of rapid and on-line analysis because of complex process more experiences or needed. In recent years, near-infrared spectroscopy technique has been used for rapid dete... | 18,844,158 |
[Study of applying fluorescence spectrum imaging to quantitative assay of proteins in bio-chip]. | In the present work, the amount and the activity of the goat anti-human IgG, to bind the human IgG labelled with fluorescein isothiocyanate (FITC), immobilized on silicon surfaces modified with APTES and APTES-Glu, respectively, were studied using the fluorescence spectrum imaging (FSI), the results of which were compa... | 18,844,170 |
[Mineralogical effect correction for pressed iron ore samples in wavelength dispersive X-ray fluorescence analysis]. | The possibility of correcting mineralogical effect for pressed powder pellets of iron ore samples was studied in wavelength dispersive X-ray fluorescence analysis of major and minor elements with 10 Chinese iron ore CRMs. Two methods were applied to reduce the influence of mineralogical effect. The first one is to chec... | 18,844,184 |
Exploring the reactivity of C(sp3)-cyclometalated Ir(III) compounds in hydrogen transfer reactions. | The manuscript describes the synthesis and full characterization of a new PC(sp(3))P-based cyclometalated Ir(III) complex that manifests an exceptional thermal stability, as well as outstanding reactivity in hydrogen transfer reactions. The described compound represents the first example of a new family of stable C(sp(... | 18,844,205 |
TCEB1 promotes invasion of prostate cancer cells. | Amplification of the long arm of chromosome 8 is one of the most recurrent findings in prostate cancer and it is associated with poor prognosis. Several minimal regions of amplification suggest multiple target genes which are yet to be identified. We have previously shown that TCEB1, EIF3S3, KIAA0196 and RAD21 are ampl... | 18,844,214 |
Index finger salvage with replantation and revascularization: revisiting conventional wisdom. | Replantation/revascularization of severely injured single digits is controversial, especially at the index position. Conventional wisdom is that these digits if salvaged will ultimately worsen residual hand function and they should be amputated. Twenty-eight cases of such index salvages were reviewed to test this hypot... | 18,844,227 |
Use of circular external fixation to maintain foot position during free tissue transfer to the foot and ankle. | Limb salvage techniques of traumatized extremities using free-tissue transfer and microsurgical techniques have become standard reconstructive methods. To our knowledge there is no published data on the incidence or likelihood of equinus following free tissue transfer about the ankle, although in our experience we have... | 18,844,229 |
Randomized clinical trial of stapled haemorrhoidopexy performed under local perianal block versus general anaesthesia. | The aim was to assess the feasibility of performing stapled haemorrhoidopexy under local anaesthesia. Fifty-eight patients with haemorrhoid prolapse were randomized to receive local or general anaesthesia. The perianal block was applied immediately peripheral to the external sphincter. Submucosal block was added after ... | 18,844,245 |
Evaluation of critical incidents in general surgery. | The analysis of adverse events is a central step in critical incident reporting, but has not been described in a surgical setting. The aim of this study was to develop an evaluation protocol and assess its feasibility. All incidents were analysed by a multidisciplinary team. A coding system based on three published the... | 18,844,272 |
Long-term follow-up of proximal versus distal laparoscopic gastric bypass for morbid obesity. | Laparoscopic gastric bypass is the 'gold standard' for treatment of morbidly obese patients in many centres. There is debate regarding the optimal length for small bowel limbs. This study aimed to determine whether the proximal or distal approach is better. Twenty-five patients undergoing primary distal gastric bypass ... | 18,844,274 |
Antioxidant metabolism induced by quinic acid. Increased urinary excretion of tryptophan and nicotinamide. | For over 50 years, hippuric/quinic acids were believed to have no biological efficacy. Here data are presented to support the hypothesis that quinic acid is not responsible for any efficacy, but rather that quinic acid nutritionally supports the synthesis of tryptophan and nicotinamide in the gastrointestinal (GI) trac... | 18,844,285 |
Antinociceptive peripheral effect of Achillea millefolium L. and Artemisia vulgaris L.: both plants known popularly by brand names of analgesic drugs. | The hydroalcohol extracts of Achillea millefolium L. (AM) and Artemisia vulgaris L. (AV), both belonging to the Asteraceae family, were evaluated by the hot plate, writhing, formalin and intestinal transit tests in an attempt to confirm their folk use as analgesic, antiinflammatory and antispasmodic agents. AM 500 and ... | 18,844,327 |
Premalbrancheamide: synthesis, isotopic labeling, biosynthetic incorporation, and detection in cultures of Malbranchea aurantiaca. | An advanced metabolite, named premalbrancheamide, involved in the biosynthesis of malbrancheamide (1) and malbrancheamide B (2) has been synthesized in double (13)C-labeled form and was incorporated into the indole alkaloid 2 by Malbranchea aurantiaca. In addition, premalbrancheamide has been detected as a natural meta... | 18,844,365 |
Imines that react with phenols in water over a wide pH range. | Cyclic imine derivatives that react with phenols, including tyrosine residues of peptides, have been developed. Reactions of the imines with phenols proceeded in water over a wide pH range (pH 2-10) at room temperature to 37 degrees C and afforded Mannich products without the need of additional catalysts. | 18,844,415 |
Role of tissue kallikrein-related peptidases in cervical mucus remodeling and host defense. | Human tissue kallikrein-related peptidases (KLKs) are 15 hormonally regulated genes on chromosome 19q13.4 encoding secreted serine proteases. Many KLKs are expressed throughout the female reproductive system and found in cervico-vaginal fluid (CVF). Immunohistochemistry was performed to determine KLK localization in th... | 18,844,451 |
Extensions, validation, and clinical applications of a feedback control system simulator of the hypothalamo-pituitary-thyroid axis. | We upgraded our recent feedback control system (FBCS) simulation model of human thyroid hormone (TH) regulation to include explicit representation of hypothalamic and pituitary dynamics, and updated TH distribution and elimination (D&E) parameters. This new model greatly expands the range of clinical and basic scie... | 18,844,475 |
Serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels in colorectal adenoma and cancer patients. | Colorectal cancer is one of the most common cancers of the gastrointestinal tract and the fourth cause of cancer death in the world. It has been shown that local chronic inflammation may lead to colorectal carcinogenesis via adenomatous polyps. Interleukin-6 and C-reactive protein are biomarkers of inflammation and ind... | 18,844,497 |
Preanalytical effects of pneumatic tube transport on routine haematology, coagulation parameters, platelet function and global coagulation. | Pneumatic tube transport of blood samples reduces turnaround times and labour. However, the preanalytical effects on new clinical chemistry parameters and instruments are not fully known. The aim of this study was to evaluate the effect of pneumatic tube transport on haematology and coagulation parameters, including pl... | 18,844,500 |
Effect of ampicillin-sulbactam on clinical capillary zone electrophoresis of serum proteins. | Capillary zone electrophoresis (CZE) is a well-accepted automated method used to separate serum proteins and detect monoclonal components. CZE uses ultraviolet detection at 214 nm to directly quantify proteins via peptide bonds. Any substance that absorbs at 214 nm and is present in serum can potentially interfere with... | 18,844,504 |
Factors associated with smoking cessation among Chinese adults in rural China. | To examine the factors associated with smoking cessation among adult Chinese males in rural China. The data were collected by face-to-face interviews at the respondents' household using interviewer-administered questionnaires. The factors associated with quitting were being residents of Guiyang, having received junior ... | 18,844,507 |
Development of a drug use resistance self-efficacy (DURSE) scale. | To develop and evaluate psychometric properties of a new instrument, the drug use resistance self-efficacy (DURSE) scale, designed for young adolescents. Scale construction occurred in 3 phases: (1) initial development, (2) pilot testing of preliminary items, and (3) final scale administration among a sample of seventh... | 18,844,509 |
Finding the right direction: the importance of open communication in a governance model of nurse management. | Change and its management is a widely researched and documented activity. Yet amidst this plethora of literature there is little that looks at the central tenets of the change process: exemplar setting; communication and executive guidance. The nursing management system at King Faisal Specialist Hospital and Research C... | 18,844,543 |
Acute (adult clinical inpatient) care nurses' attitudes towards and knowledge of nationally endorsed 5As smoking cessation guidelines. | Nurses are expected to be involved in health promotion, including smoking cessation. This study aimed to assess nurses' knowledge, sense of responsibility and willingness to provide smoking cessation interventions as described in the national 5As guideline. Data were collected by a survey distributed to a convenience s... | 18,844,545 |
Nurses on the move: diversity and the work environment. | Over 191 million people make up the international migrant population of today. Their numbers have doubled since 1970, with women now accounting for almost half. The migrant population has been transformed and is changing the very nature of society in both source and destination countries. Greater differences in culture... | 18,844,573 |
PCR-based simultaneous analysis of the interferon-alpha family reveals distinct kinetics for early interferons. | Here we describe a PCR-based analysis system that allows the simple simultaneous assessment of murine interferons (IFN)-alpha and IFN-beta induction in a single reaction. In this analysis, the so-called early IFN-alpha4 can be distinguished from the so-called late IFN-nonalpha4 by employing a primer mixture that amplif... | 18,844,580 |
Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice. | The dermis and epidermis are alternative sites for prophylactic vaccination that have received renewed interest in recent years, not only because of the ease of access to the skin, but also its unique immunological properties. This review discusses the characteristics of the skin, current knowledge on skin immunity and... | 18,844,594 |
Crohn's disease but not chronic ulcerative colitis induces the expression of PAI-1 in enteric neurons. | Chronic inflammation of the intestinal wall is the common characteristic of Crohn's disease and ulcerative colitis; disorders, which in some cases can be difficult to distinguish. The inflammation also affects the local neuronal plexuses of the enteric nervous system. It is known that plasminogen activator inhibitor-1 ... | 18,844,621 |
Recommendations for routine reporting on indications for cesarean delivery in developing countries. | Cesarean delivery rates are increasing rapidly in many developing countries, particularly among wealthy women. Poor women have lower rates, often so low that they do not reach the minimum rate of 1 percent. Little data are available on clinical indications for cesarean section, information that could assist in understa... | 18,844,646 |
Quality of life of caregivers of very low-birthweight infants. | The health and developmental outcomes of very low-birthweight infants are unpredictable over the first year of life. This uncertainty may have meaningful consequences for parents' quality of life. The objective of this study was to explore the quality of life of caregivers of these infants. Primary caregivers of very l... | 18,844,647 |
Quantitative correlation between theoretical molecular descriptors and drug-HSA binding affinities for various cox-2 inhibitors. | In this study, quantitative structure-protein binding relationships have been derived to predict the binding affinities of cox-2 inhibitor drugs to HSA from the structure of drug molecules. Drug-HSA binding affinities were determined using fluorescence spectroscopic technique. For the calculation of theoretical molecul... | 18,844,676 |
Experimental and QSAR of acetophenones as antibacterial agents. | Antibacterial activity of 20 acetophenone derivatives was evaluated against two Gram-positive and three Gram-negative organisms, namely, Bacillus subtilis NCIM 2718, Staphylococcus aureus NCIM5021, Salmonella typhi NCIM2501, Enterobacter aerogenes NCIM5139, and Proteus vulgaris NCIM2813 by two-fold dilution method. The... | 18,844,677 |
Evaluation of the effect of the specific CCR1 antagonist CP-481715 on the clinical and cellular responses observed following epicutaneous nickel challenge in human subjects. | The CC-chemokine receptor-1 (CCR1) is thought to be involved in recruitment of inflammatory cells in allergic contact dermatitis (ACD). CP-481715 is a specific antagonist of CCR1. To determine the inhibitory effects of CP-418 715 in ACD by evaluating the clinical signs and cellular infiltration in skin biopsies followi... | 18,844,696 |
Anogenital allergic contact dermatitis, the role of spices and flavour allergy. | In patients with vulval or anogenital dermatitis, irritant contact dermatitis is more common than allergic contact dermatitis. The reported frequency and relevance of contact sensitivity in anogenital dermatitis varies greatly. To determine the frequency and relevance of contact sensitization in a Dutch group of female... | 18,844,699 |
Trends of contact allergy to fragrance mix I and Myroxylon pereirae among Danish eczema patients tested between 1985 and 2007. | Fragrance contact allergy has for long been recognized as an important health issue. In Denmark, the frequency of fragrance mix (FM) I contact allergy increased between 1985-1986 and 1997-1998 among male and female dermatitis patients. To investigate the development of FM I and Myroxylon pereirae (MP) contact allergy b... | 18,844,700 |
Resistant arterial hypertension is associated with higher blood levels of complement C3 and C-reactive protein. | Arterial hypertension is associated with increased plasma levels of complement C3, C4, and C-reactive protein (CRP). The aim of the study was to compare these laboratory markers in patients with resistant arterial hypertension (RAH) and controlled arterial hypertension (CAH). Patients with RAH (n = 34), those with CAH ... | 18,844,762 |
Is patients' insurance coverage associated with prescribing after hospitalization for severe, poorly controlled hypertension? | High medication costs may be a significant cause of nonadherence and threaten recent gains in hypertension treatment. It is unclear whether prescribing patterns differ with patients' insurance coverage. The objective of this study was to determine whether insurance coverage, reported difficulty affording medications, o... | 18,844,763 |
Anger types: heritability and relation to blood pressure, body mass index, and left ventricular mass. | The relationship between anger and cardiovascular morbidity has not been investigated among Mexican Americans. This exploratory study examined the heritability of anger types and their relationship to cardiovascular variables in samples of unrelated and related Mexican Americans residing near Chicago, Illinois. All of ... | 18,844,765 |
Effect of salicylic acid on salinity-induced changes in Brassica juncea. | Seeds of Indian mustard (Brassica juncea (L.) Czern. et Coss.) were exposed to 0, 50, 100 and 150 mmol/L NaCl for 8 h and seeds were sown in an earthen pot. These stressed seedlings were subsequently sprayed with 10 micromol/L salicylic acid (SA) at 30 d and were sampled at 60 d to assess the changes in growth, photosy... | 18,844,778 |
C5 inhibitor rEV576 protects against neural injury in an in vitro mouse model of Miller Fisher syndrome. | Guillain-Barré syndrome and its clinical variants, including the anti-GQ1b ganglioside-mediated Miller Fisher syndrome (MFS), comprise the world's leading cause of acute neuromuscular paralysis. Presently, no specific drug therapies exist. The complement cascade, which is activated in these patients, forms an attractiv... | 18,844,789 |
Perceived barriers and benefits to research participation among school administrators. | Gaining access to conduct research in schools can be challenging, but little has been done to directly assess school administrators' perceptions of research. The purpose of this qualitative study was to increase understanding of barriers and benefits of research participation as perceived by superintendents and princip... | 18,844,810 |
Self-reported substance use and sexual behaviors among adolescents in a rural state. | Research finds a strong association between substance use and risky sexual behavior but more needs to be known about this relationship. Few studies have examined this relationship among rural sixth- to eighth-grade students. As such, the purposes of this study were to provide a descriptive profile of rural sixth- to ei... | 18,844,811 |
Regulation of vitamin D homeostasis: implications for the immune system. | Vitamin D homeostasis in the immune system is the focus of this review. The production of both the activating (25- and 1alpha-hydroxylase) and the metabolizing (24-hydroxylase) enzymes by cells of the immune system itself, indicates that 1,25(OH)(2)D(3) can be produced locally in immune reaction sites. Moreover, the st... | 18,844,839 |
Vitamin D: a D-Lightful health perspective. | Sunlight provides most humans with their vitamin D requirement. Adequate vitamin D(3) by synthesis in the skin or from dietary and supplemental sources is essential for bone health throughout life. Vitamin D deficiency is defined as a 25(OH)D concentration <20 ng/mL (50 nmol/L); vitamin D sufficiency as a 25(OH)D &g... | 18,844,847 |
Towards establishing a national colorectal cancer database: lessons learnt from Bio21 molecular medicine informatics model. | Collecting data regarding treatment and outcomes of patients with cancer, for both audit and research purposes, is a common but challenging goal. Modern technology promises greater ease and sophistication for data collection, linkage and analysis, but many traditional challenges remain. Here we relate our experience of... | 18,844,914 |
Immunohistochemical detection of carcinoma in radical prostatectomy specimens following hormone therapy. | Following hormone therapy, residual carcinoma is frequently difficult to identify on HE-stained prostatectomy specimens. The aim of the present study was therefore to investigate whole-mounted specimens obtained by radical prostatectomy from patients who had undergone hormone therapy. Formalin-fixed and paraffin-embedd... | 18,844,933 |
Histological characteristics of 21 Papua New Guinean children with high-grade B-cell lymphoma, which is frequently associated with EBV infection. | The aim of the present study was to confirm the histopathological features of aggressive B-cell lymphoma in Papua New Guinea (PNG)-an EBV endemic region. The immunophenotypic features and expression of EBV-encoded proteins and RNA in B-cell lymphomas were analyzed in 21 PNG children, and compared to the corresponding f... | 18,844,934 |
Follicular lymphoma with marked infiltration of eosinophils. | Eosinophilia and tissue infiltration by eosinophils are frequent findings in Hodgkin lymphoma, but they are extremely rare in B-cell lymphoma. Reported herein is a case of follicular lymphoma with extensive lymph node infiltration by eosinophils. The patient was a 71-year-old woman who had a mass in the vicinity of the... | 18,844,935 |
Mucoepidermoid carcinoma of the thyroid gland showing marked ciliation suggestive of its pathogenesis. | Mucoepidermoid carcinoma of the thyroid gland is a rare tumor first described by Rhatigan et al. in 1977. Its pathogenesis is still controversial. With regard to its most likely origin, some authors have suggested that it arises directly from follicular epithelium whereas others have proposed that it arises from ultimo... | 18,844,942 |
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