title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Targets for hydrogen-peroxide-induced damage to suspension and biofilm cells of Streptococcus mutans. | Hydrogen peroxide (H2O2) is considered a major endogenous source of oxidative stress to oral bacteria and also is widely used in oral care products. Our study objectives were to identify specific targets for H2O2-induced damage to cells of Streptococcus mutans in suspensions and monospecies biofilms and to differentiat... | 18,923,556 |
Transposon Tn5281 is the main distributor of the aminoglycoside modifying enzyme gene among isolates of Enterococcus faecalis in Tehran hospitals. | Infections with high levels of gentamicin-resistant (HLGR) isolates of Enterococcus faecalis are common in Tehran hospitals. Genes encoding such resistance are transmissible by conjugation at high frequency. The purpose of this study was to determine the existence of Tn5281 and its flanking aminoglycoside modifying enz... | 18,923,558 |
PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions. | The discovery 10 years ago of PGC-1alpha represented a major milestone towards understanding of the molecular processes regulating energy metabolism in many tissues, including skeletal muscle. PGC-1alpha orchestrates a metabolic program regulating oxidative lipid metabolism and insulin sensitivity. This is essentially ... | 18,923,559 |
Heat shock proteins and exercise: a primer. | Heat shock proteins (HSPs) are, in general, prosurvival molecules within the cellular environment, and the overexpression of even just 1 family of HSPs can lead to protection against and improvements after a variety of stressors. Not surprisingly, a fertile area of study has grown out of efforts to exploit the innate b... | 18,923,583 |
Serum lipid profile in malnourished Nigerian children in Zaria. | There is paucity of data on the pattern of serum lipids in malnourished children in Zaria. Most of the reported studies were carried out in southern part of Nigeria. The overall objective of this study was therefore to measure serum lipids in children with PEM in Zaria with the view to recommending its use in them. Ser... | 18,923,595 |
Cross-polarized wave generation in the UV region. | We demonstrate experimentally the generation of cross-polarized femtosecond pulses in BaF2 crystal in the UV region. We show that unsaturated cross-polarized wave generation in the UV is six times more efficient than in the visible region, and we deduce the corresponding wavelength dispersion of the third-order nonline... | 18,923,602 |
Dark-spot formation by vector beams. | Dark-spot formation is demonstrated by calculating electric-field distribution near the focus produced by focusing higher-order transverse-mode vector beams with radial and azimuthal polarizations in addition to Laguerre-Gaussian beams with linear and circular polarizations. The size of the dark spot in the radial dire... | 18,923,611 |
Coherence transfer between atomic ground states by the technique of stimulated Raman adiabatic passage. | We experimentally and theoretically demonstrate that the atomic coherence can be completely transferred or arbitrarily contributed among the different levels in a four-level atomic (tripod) scheme by a group of coupled pulse sequences. This technique can be applied to the information conversion in slow-light storage, q... | 18,923,629 |
Enhanced Luminescence from Emissive Defects in Aggregated Conjugated Polymers. | Degradation experiments and model studies suggested that the longer lived green fluorescence from an aggregated poly(p-phenylene ethynylene) (PPE) was due to the presence of highly emissive, low-energy, anthryl defect sites rather than the emissive conjugated polymer excimers proposed in a previous report. After elucid... | 18,923,651 |
Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte. | Transcription control at a distance is a critical mechanism, particularly for contiguous genes. The peptidylarginine deiminases (PADs) catalyse the conversion of protein-bound arginine into citrulline (deimination), a critical reaction in the pathophysiology of multiple sclerosis, Alzheimer's disease and rheumatoid art... | 18,923,650 |
Stroke and conditions that mimic it: a protocol secures a safe early recognition. | Certain disorders may be falsely diagnosed as stroke. We examined the efficacy of the diagnostic protocol that is followed in our stroke unit and was designed in order to early differentiate more efficiently between stroke and conditions that mimic it. METHODS-PATIENTS: Three hundred sixty-two elderly patients (196 mal... | 18,923,652 |
Toxoplasmosis during pregnancy: a case report and review of the literature. | Although toxoplasmosis is considered harmless for a non-pregnant woman, it is potentially harmful during pregnancy, especially at first trimester. The aim of this study is to increase our alertness and monitoring in case of toxoplasmosis during pregnancy, given that when diagnosed it can be effectively treated.We prese... | 18,923,664 |
The effect of recombinant human erythropoietin treatment on insulin resistance and inflammatory markers in non-diabetic patients on maintenance hemodialysis. | Iron overload and inflammation might participate in the pathogenesis of insulin resistance in community. The improvement of insulin resistance in hemodialysis (HD) patients is frequently seen after correction of anemia. The aim of this study was to investigate the influence of recobinant humam erythropoietin (Epo) trea... | 18,923,665 |
Quality of life of children and adolescents with diabetes of Northern Greek origin. | To culturally adapt the diabetes- specific quality of life (QOL) instrument PedsQL 3.0 Diabetes Module (DM) and the generic QOL instrument PedsQL 4.0 Generic Core Scales (GCS) to the population of Greek diabetic children. Also, to evaluate QOL in youths with type 1 diabetes, compare it with that of healthy youths, and ... | 18,923,667 |
Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants. | The neurotransmitter serotonin (5-HT) plays an important role in both the peripheral and central nervous systems. The biosynthesis of serotonin is regulated by two rate-limiting enzymes, tryptophan hydroxylase-1 and -2 (TPH1 and TPH2). We used a gene-targeting approach to generate mice with selective and complete elimi... | 18,923,670 |
Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation. | Understanding the molecular mechanisms controlling pluripotency in embryonic stem cells (ESCs) is of central importance towards realizing their potentials in medicine and science. Cross-species examination of transcriptional co-expression allows elucidation of fundamental and species-specific mechanisms regulating ESC ... | 18,923,680 |
"It is me who endures but my family that suffers": social isolation as a consequence of the household cost burden of Buruli ulcer free of charge hospital treatment. | Despite free of charge biomedical treatment, the cost burden of Buruli ulcer disease (Bu) hospitalisation in Central Cameroon accounts for 25% of households' yearly earnings, surpassing the threshold of 10%, which is generally considered catastrophic for the household economy, and calling into question the sustainabili... | 18,923,711 |
ESBL genotypes in fluoroquinolone-resistant and fluoroquinolone-susceptible ESBL-producing Escherichia coli urinary isolates in Manitoba. | Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli are increasingly common in nosocomial and community settings. Furthermore, fluoroquinolone (FQ) and even multidrug resistance (MDR) appear to be associated with certain ESBL genotypes. The purpose of the present study was to determine which ESBL genotyp... | 18,923,714 |
Antibiotic availability and the prevalence of pediatric pneumonia during a physicians' strike. | Antibiotics are widely believed to be overpre-scribed for pediatric respiratory infections, yet there are few data available on the effect of a sudden decrease in antibiotic availability on pediatric infectious disease. To determine whether the prevalence of radiographically diagnosed pneumonia changed over a period of... | 18,923,715 |
A prospective two years study of first trimester screening for Down syndrome. | Nowadays maternal age of pregnant women has increased in most developed countries. The rate of women above 35 years old constitutes about 15% of pregnancies. The aim of our study is to prove that by first trimester screening, the number of women who have indication for invasive prenatal diagnostic procedure is signific... | 18,923,756 |
Revascularization treatment in patients with coronary artery disease. | The choice of optimal revascularization strategy in patients with coronary artery disease (CAD) is becoming more challenging lately, due to recent advances in percutaneous coronary intervention (PCI) and coronary artery bypass grafting surgery (CABG). On one hand, drug-eluting stents (DES) have emerged as a solution to... | 18,923,757 |
Isolated double gastric rupture caused by blunt abdominal trauma in an eighteen months old child: a case report. | We report a case of an isolated double gastric rupture, resulted from blunt abdominal trauma, that we successfully repaired by primary closure. A 18-month-old girl injured in a motor vehicle accident was admitted to our hospital where the plain X-ray and the CT findings revealed the presence of free abdominal air. An i... | 18,923,758 |
Methicillin-resistant Staphylococcus aureus in a Canadian intensive care unit: Delays in initiating effective therapy due to the low prevalence of infection. | Methicillin-resistant Staphylococcus aureus (MRSA) infection in intensive care units (ICUs) has increased dramatically in prevalence in recent years, and is associated with increased morbidity, mortality and cost of care. The aim of the present study was to describe the epidemiology and outcomes of MRSA infection in th... | 18,923,765 |
Biliary atresia: we still operate too late. | To analyze the age at surgery for children with biliary atresia and their survival periods without need for liver transplantation. The study was performed at Hospital de Clínicas de Porto Alegre, in Porto Alegre, state of Rio Grande do Sul, Brazil. The medical records of patients operated between 1982 and 2007 who were... | 18,923,787 |
High-throughput self-interaction chromatography: applications in protein formulation prediction. | Demonstrate the ability of an artificial neural network (ANN), trained on a formulation screen of measured second virial coefficients to predict protein self-interactions for untested formulation conditions. Protein self-interactions, quantified by the second virial coefficient, B22, were measured by self-interaction c... | 18,923,812 |
Visante anterior segment OCT in a patient with gas bubbles in the anterior chamber after femtosecond laser corneal flap formation. | A patient with anterior chamber gas bubbles after LASIK flap formation with femtosecond laser is presented. A 33-year-old male patient had LASIK for myopia with corneal flap formation with IntraLase FS30 femtosecond laser. In the right eye, air bubbles were observed in anterior chamber after successful flap formation. ... | 18,923,814 |
Comparative biomechanical study of the Ligament Plate and other fixation devices in ACL reconstruction. | The objective of this study was to evaluate and compare the biomechanical properties of the Ligament Plate with other femoral fixation devices. The Ligament Plate and three different femoral fixation devices were used in fixation of 60 porcine femora and harvested porcine tendons. For each fixation device, a porcine gr... | 18,923,833 |
Mutations in the paralogous human alpha-globin genes yielding identical hemoglobin variants. | The human alpha-globin genes are paralogues, sharing a high degree of DNA sequence similarity and producing an identical alpha-globin chain. Over half of the alpha-globin structural variants reported to date are only characterized at the amino acid level. It is likely that a fraction of these variants, with phenotypes ... | 18,923,834 |
Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology. | Recently, sporadic amyotrophic lateral sclerosis (SALS), a fatal neurological disease, has been shown to be a multisystem proteinopathy of TDP-43 in which both neurons and glial cells in the central nervous system are widely affected. In general, the natural history of SALS is short (<5 years). However, it is also k... | 18,923,836 |
Brain and mind operational architectonics and man-made "machine" consciousness. | To build a true conscious robot requires that a robot's "brain" be capable of supporting the phenomenal consciousness as human's brain enjoys. Operational Architectonics framework through exploration of the temporal structure of information flow and inter-area interactions within the network of functional neuronal popu... | 18,923,856 |
Interventional radiology in the diagnosis, management, and follow-up of pseudoaneurysms. | Arterial wall disruption, as a consequence of inflammation/infection, trauma (penetrating or blunt), or iatrogenic causes, may result in pseudoaneurysm formation. Currently, iatrogenic causes are increasing as a result of the growth of endovascular intervention. The frequency of other causes also seems to be increasing... | 18,923,864 |
Relationship between duration of teriparatide therapy and clinical outcomes in postmenopausal women with osteoporosis. | The extent to which fracture protection and safety varies with increasing time on teriparatide [rhPTH(1-34)] therapy is a clinically relevant unanswered question. In postmenopausal women with osteoporosis, increased duration of teriparatide versus placebo treatment was associated with a progressive decrease in the rate... | 18,923,884 |
Acculturation of host individuals: immigrants and personal networks. | There has been a vast amount of research on the changes experienced by immigrants, but little is known about the changes experienced by host individuals. This article focuses on the role of host individuals in the networks of relations between immigrant populations and the communities from the dominant culture, as well... | 18,923,893 |
Migrant well-being is a multilevel, dynamic, value dependent phenomenon. | Research demonstrates that the well-being of migrants is a multilevel, dynamic, and value dependent phenomenon. It is multilevel because risk and protective factors are present at various ecological planes, from the individual to the social sphere. It is dynamic because objective and subjective risk and protective fact... | 18,923,898 |
Absorption, excretion and retention of 51Cr from labelled Cr-(III)-picolinate in rats. | The bioavailability of chromium from Cr-picolinate (CrPic(3)) and Cr-chloride (CrCl(3)) was studied in rats using (51)Cr-labelled compounds and whole-body-counting. The intestinal absorption of Cr was twice as high from CrPic(3) (1.16% vs 0.55%) than from CrCl(3), however most of the absorbed (51)Cr from CrPic(3) was e... | 18,923,913 |
Increased spontaneous osteoclastogenesis from peripheral blood mononuclear cells in phenylketonuria. | Phenylketonuria (PKU) is commonly complicated by a progressive bone impairment of uncertain aetiology. The therapeutic phenylalanine (Phe)-restricted diet and the possible noxious effects of high plasma Phe concentrations on bone have previously been suggested as possible determinant factors. Since osteoclasts are invo... | 18,923,919 |
Influence of gender on ventilatory efficiency during exercise in young children. | In this study, we assessed the ventilatory response in 84 children (46 males: age 8.1 +/- 1.0 years, body mass 34.2 +/- 7.9 kg, height 1.32 +/- 0.16 m; 38 females: age 8.0 +/- 0.8 years, body mass 31.7 +/- 8.7 kg, height 1.31 +/- 0.08 m) during a cycle ergometer test to determine if there was an influence of gender on ... | 18,923,953 |
A comparison of lactate indices during ramp exercise using modelling techniques and conventional methods. | The aim of this study was to compare the lactate indices provided by single- and double-breakpoint models with lactate thresholds obtained with conventional methods. Arterial samples for the determination of lactate concentrations were drawn from eight participants at rest and every minute during a ramp test (15 W x mi... | 18,923,955 |
Development of a partial Balint's syndrome in a congenitally deaf patient presenting as pseudo-aphasia. | We present a 56 year-old, right-handed, congenitally deaf female who exhibited a partial Balint's syndrome accompanied by positive visual phenomena restricted to her lower right visual quadrant (e.g., color band, transient unformed visual hallucinations). Balint's syndrome is characterized by a triad of visuo-ocular sy... | 18,923,965 |
Serous otitis media in the 20th and 21st centuries: evolving views and treatments. | The historical study of serous otitis media (SOM) demonstrates steps in recognition of the disease, shifts in prevalence, and relationships between the disease's affect and evolving economic bases of society. SOM, although noted in early Roman and Arabic medicine, was only identified as a distinct and significant patho... | 18,923,967 |
Induction and exacerbation of psoriasis with TNF-blockade therapy: a review and analysis of 127 cases. | There are reports of rare adverse effects of tumor necrosis factor (TNF) inhibitors, including infections, malignancies, and induction of autoimmune conditions. Intriguing, are cases of induction or exacerbation of psoriasis in conjunction with TNF inhibitor therapy, given that they are approved for treatment of the sa... | 18,923,992 |
Time-response effects of testicular gene expression profiles in Sprague-Dawley male rats treated with di(n-butyl) phthalate. | Phthalate esters were reported to damage fetal and postnatal testes of experimental animals, but the molecular mechanisms underlying these effects remain unknown. The time-response effects of di(n-butyl) phthalate (DBP) on the expression patterns of the testicular genes in male Sprague-Dawley rats were examined for dif... | 18,923,996 |
Does arsenic exposure increase the risk for prostate cancer? | Arsenic has been well documented as the major risk factor for blackfoot disease (BFD), a unique peripheral vascular disease that was endemic to the southwestern coast of Taiwan, where residents consumed artesian well water containing high levels of arsenic for more than 50 yr. Chronic arsenic exposure was also reported... | 18,923,998 |
Arrhythmogenic right ventricular cardiomyopathy--time for Nordic cooperation! | This editorial discusses arrhythmogenic right ventricular cardiomyopathy (ARVC) with respect to diagnosis and organisation of patient care. Two papers in the current issue are commented upon. Aneq and coworkers present a long-term echocardiographic study on ARVC patients. Baseline changes were seldom diagnostic, but ov... | 18,924,017 |
Efficacy of intra-operative radiofrequency ablation in patients with permanent atrial fibrillation undergoing concomitant mitral valve replacement. | Permanent atrial fibrillation (AF) is present before operation and persists after surgery in 30-40% of patients undergoing mitral valve surgery. Using the maze procedure, 75-82% of patients can be cured of AF, but the procedure is difficult and long lasting. Percutaneous radiofrequency (RF) ablation has emerged as an e... | 18,924,020 |
Prevention of pediatric drug calculation errors by prehospital care providers. | Calculating weight-based drug doses for pediatric patients is difficult, with significant error potential. In the prehospital setting, few safeguards currently avert pediatric drug administration errors. We sought to determine whether use of a protocol-specific pediatric code card enables prehospital care providers to ... | 18,924,013 |
Pay for performance improves rural EMS quality: investment in prehospital care. | To evaluate the effect of a system of financial reward for emergency medical technicians (EMTs) who meet selected quality marker goals. This project was reviewed by an institutional review board (IRB) and was found to be exempt from IRB review. Two operational and four clinical markers were targeted for improvement. Ba... | 18,924,014 |
[Myopericarditis complicated with cardiogenic shock mimicking acute coronary syndrome with ST elevation in a patient with hyperthyroidism and diabetes mellitus]. | We describe a case of a 56 year old man with myopericarditis complicated with cardiogenic shock within first 3 days, mimicking on admission acute myocardial infarction with ST elevation in inferior ECG leads. Additionally, patient presented hyperthyroidism and totally decompensated diabetes mellitus. He required during... | 18,924,029 |
[Liberalisation of preoperative fasting guidelines: effects on patient comfort and clinical practicability during elective laparoscopic surgery of the lower abdomen]. | In this study, the recently liberalised national guidelines for preoperative fasting were evaluated from the view point of the patients and according to their clinical usability. Patients undergoing elective laparoscopic gynaecological surgery were randomised into two groups. Patients in the long-time NPO-group (LTNPO-... | 18,924,048 |
[Suspicion of a newly appearing hypertrophic obstructive cardiomyopathy in a patient treated for hepatocellular carcinoma]. | A 42-year-old women presented with shortness of breath, tachycardia and weakness to our department. Five years ago she had been diagnosed with hepatocellular carcinoma for which an extended hemihepatectomy had been performed. The clinical examination revealed a systolic murmur over the artic region. Echocardiography sh... | 18,924,054 |
Splenogonadal fusion. | We report a case of an 11-year-old boy who presented with a painless left scrotal mass of one year's duration. Clinical examination and diagnostic modalities indicated a solid left testicular mass. Exploration was done and a complete splenogonadal fusion was found. The ectopic splenic tissue was completely removed with... | 18,924,073 |
Pseudoaneurysm of a branch of the profunda femoris artery following distal locking of an intramedullary hip nail: an unusual anatomical location. | Vascular complications following internal fixation of trochanteric femoral fractures are extremely rare. Iatrogenic injury to the profunda femoris artery or one of its branches and resultant pseudoaneurysm formation has been documented, most commonly following sliding hip screw fixation and typically arises on the post... | 18,924,081 |
Prevention of infections associated with vascular catheters. | The expanding use of vascular catheters has increased the need to prevent hazardous infectious complications. Since bloodstream infection is the most common serious complication of indwelling vascular catheters, the proof that a potentially preventive approach is truly protective against clinical infection requires a s... | 18,924,093 |
NO-sulindac inhibits the hypoxia response of PC-3 prostate cancer cells via the Akt signalling pathway. | Nitric oxide-donating non-steroidal anti-inflammatory drugs are safer than traditional NSAIDs and inhibit the growth of prostate cancer cells with greater potency than NSAIDs. In vivo, prostate cancer deposits are found in a hypoxic environment which induces resistance to chemotherapy. The aim of this study was to asse... | 18,924,134 |
Cervical prephrenic interneurons in the normal and lesioned spinal cord of the adult rat. | Although monosynaptic bulbospinal projections to phrenic motoneurons have been extensively described, little is known about the organization of phrenic premotor neurons in the adult rat spinal cord. Because interneurons may play an important role in normal breathing and recovery following spinal cord injury, the presen... | 18,924,146 |
Neurodevelopmental outcomes of children with low-grade gliomas. | As a group, children with low-grade gliomas (LGGs) enjoy a high rate of long-term survival and do not require the intensity of neurotoxic treatments used with higher risk pediatric brain tumors. Because they are generally considered to have favorable neurobehavioral outcomes, they have not been studied as thoroughly as... | 18,924,158 |
Inherited disorders as a risk factor and predictor of neurodevelopmental outcome in pediatric cancer. | Each year in the United States, an average of one to two children per 10,000 develop cancer. The etiology of most childhood cancer remains largely unknown but is likely attributable to random or induced genetic aberrations in somatic tissue. However, a subset of children develops cancer in the setting of an underlying ... | 18,924,162 |
Valence-state analysis through spectroelectrochemistry in a series of quinonoid-bridged diruthenium complexes [(acac)(2)Ru(mu-L)Ru(acac)(2)](n) (n=+2, +1, 0, -1, -2). | The quinonoid ligand-bridged diruthenium compounds [(acac)(2)Ru(mu-L(2-))Ru(acac)(2)] (acac(-)=acetylacetonato=2,4-pentanedionato; L(2-)=2,5-dioxido-1,4-benzoquinone, 1; 3,6-dichloro-2,5-dioxido-1,4-benzoquinone, 2; 5,8-dioxido-1,4-naphthoquinone, 3; 2,3-dichloro-5,8-dioxido-1,4-naphthoquinone, 4; 1,5-dioxido-9,10-anth... | 18,924,186 |
Effect of osmolytes on pressure-induced unfolding of proteins: a high-pressure SAXS study. | Herein, we explore the effect of different types of osmolytes on the high-pressure stability and tertiary structure of a well-characterized monomeric protein, staphylococcal nuclease (SNase). Changes in the denaturation pressure and the radius of gyration are obtained in the presence of different concentrations of trim... | 18,924,198 |
CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. | The initial step in Langerhans cell (LC) migration from the epidermis to the lymph node involves migration of maturing LC into the dermis. Here, we investigated the migration of LC out of the epidermis after exposure of the skin to contact allergens. Ex vivo intact human skin, epidermal sheets, and LC derived from the ... | 18,924,211 |
Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta. | Regulatory T cells exert their function through the modulation of both T and B cell responses. Our previous studies demonstrated that IL-10-producing Treg (Tr1) can induce B cells to secrete IgG4 in a cell-contact-dependent manner. The benefit of such non-inflammatory B-cell responses is apparent in the hyporesponsive ... | 18,924,213 |
Expression of AP-2delta in the developing chick retina. | AP-2 is a family of transcription factors that play important roles during embryonic development. Two AP-2 genes, AP-2alpha and AP-2beta, have previously been characterized in chick retina. Here, we demonstrate that a third member of the chicken AP-2 family, AP-2delta, is primarily expressed in the retina and brain, wi... | 18,924,234 |
BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development. | The endocardial cushions play a critical role in septation of the four-chambered mammalian heart and in the formation of the valve leaflets that control blood flow through the heart. Within the outflow tract (OFT), both cardiac neural crest and endocardial-derived mesenchymal cells contribute to the endocardial cushion... | 18,924,235 |
Is there a need for autopsies in the management of fungal disease? | The autopsy rates in Germany became low like in other European, American and Asian countries. Main reasons for this development are the lack of acceptance of autopsy in the society as well as in the medical profession, the introduction of a requirement for consent, unclear legal position, the public health system, pres... | 18,924,260 |
The continuing process of parental grief. | The death of a child is an incomprehensible and devastating loss. Grief for parents is lifelong, becoming the connection between parent and child. To extend and deepen current understanding of parental grief, a new survey instrument was developed, combining quantitative and qualitative measures. The qualitative finding... | 18,924,293 |
[Burnout in volunteer health workers]. | While diverse studies carried out in nursing and medical personnel have demonstrated that health workers can be subject to burnout, little effort has been focused on investigating burnout in volunteer hospital workers. The aim of the present study was to verify if burnout exists with volunteer auxiliary personnel and i... | 18,924,296 |
Reliability of verbal descriptors of dyspnea and their relationship with perceived intensity and unpleasantness. | Verbal descriptors of dyspnea have been suggested as being useful in providing information on the underlying pathophysiology. However, little is known about the reliability of these descriptors. The present study examined the reliability of a German language list of respiratory symptom descriptors and studied the assoc... | 18,924,297 |
Exposure to occupational carcinogens and lung cancer risk. Evolution of epidemiological estimates of attributable fraction. | Lung cancer is the leading cause of cancer death world-wide. Among the possible causes, occupational risk factors play a major role and are potentially preventable. We reviewed the scientific evidence about lung cancer burden due to occupation. We reviewed the literature and selected population case-control and cohort ... | 18,924,308 |
[Helicobacter pylori infection: what to do after first intent treatment failure?]. | First intent therapy of H. pylori infection is triple therapy combining PPI, amoxicillin and clarithromycin for 7 to 10 days. Due to the increasing rate of primary resistance to clarithromycin, expected eradication rates are below 70%. Consequently, treatment effect has to be systematically assessed by urea breath test... | 18,924,328 |
[Budd-Chiari syndrome--hematologists' part in the multidisciplinary approach]. | Budd-Chiari syndrome presents a serious disease with a complex etiology and clinical manifestations, which is associated with high morbidity and mortality. An early diagnosis and therapy is mandatory due to the severity of disease and therapy contains the treatment of underlying disorder, anticoagulation therapy and th... | 18,924,345 |
[Superior mesentery artery embolization as a complication of the primary angioplasty solved by local thrombolysis]. | Acute mesentery artery embolization is a rare complication of invasive catheterizations. The incidence is unknown. In case of late diagnosis the mortality may reach up to 93%. Acute abdominal pain, vomitus, rapid and sudden bowel evacuation with or without blood are the typical symptoms of the disease. Plain X-Rays of ... | 18,924,349 |
Comparison of body mass index and waist circumference as predictors of all-cause mortality in a male insured lives population. | Obesity assessed by body mass index (BMI) is associated with increased mortality risk, but there is uncertainty about whether BMI is the best way to measure obesity. Waist circumference (WC) has been proposed as a better measure. The Swiss Re BMI/WC Study was conducted to determine whether BMI or WC is a better predict... | 18,924,364 |
"Complicated" right bundle branch block. | Isolated right bundle branch block is generally regarded as a benign finding in the absence of underlying structural heart disease. The presence of "electrocardiographically-complicated" right bundle branch block should alert the medical director to occult heart disease, which might impact on long-term survival. | 18,924,370 |
Vibrio tapetis-like strain isolated from introduced Manila clams Ruditapes philippinarum showing symptoms of brown ring disease in Norway. | The Manila clam Ruditapes philippinarum was introduced to Norway in 1987 and was produced in 2 hatcheries until 1991. Clam seed was planted at 6 sites. Two sites were on the Island of Tysnes, south of Bergen. Surviving adult Manila clams were recovered in 1995 and 1996. In the present study, Manila clams from the origi... | 18,924,380 |
Grandparent caregivers. | Although grandparent caregiving is not a new phenomenon in the United States, there has been a dramatic increase in grandparent-headed households in the last two decades. Many of these care providers are older and feel somewhat unprepared to raise a new generation of children. As a result, grandparent caregivers are at... | 18,924,399 |
[Genetic aspects of the interrelation between alkaloids and chemical elements in Atropa belladonna L. and Glaucium flavum Grantz. plants]. | The variability of the contents of tropane and isoquinoline alkaloids, ashes, Na, K, Ca, Mg, Fe, Mn, Cu, Zn, Co, Mo, Cr, Al, Ba, V, Ni, Sr, Cd, Pb, J, and Ag was studied in individual plants of the industrial population of belladonna (Atropa belladonna L.) and yellow horned poppy (Glaucium flavum Crantz.). Numerous lin... | 18,924,415 |
[Antioxidant properties of essential oils from lemon, grapefruit, coriander, clove, and their mixtures]. | Antioxidant properties of individual essential oils from lemon (Citrus limon L.), pink grapefruit (Citrus paradise L.), coriander (Coriandrum sativum L.), and clove (Caryophyllus aromaticus L.) buds and their mixtures were studied by capillary gas-liquid chromatography. Antioxidant activity was assessed by oxidation of... | 18,924,419 |
5-HT system in the gut: roles in the regulation of visceral sensitivity and motor functions. | 5-Hydroxytryptamine (5-HT) is a major transmitter molecule within the gastrointestinal tract. It is contained in enterochromaffin (EC) cells, which form part of the epithelial lining of the gut and in enteric neurones in the submucosal and myenteric plexuses. 5-HT is present in murine mucosal mast cells in the lamina p... | 18,924,445 |
Cannabinoids and gastrointestinal motility: animal and human studies. | The plant Cannabis has been known for centuries to be beneficial in a variety of gastrointestinal diseases, including emesis, diarrhea, inflammatory bowel disease and intestinal pain. delta9-tetrahydrocannabinol, the main psychotropic component of Cannabis, acts via at least two types of cannabinoid receptors, named CB... | 18,924,447 |
New insights into the pathophysiology of IBS: intestinal microflora, gas production and gut motility. | Irritable bowel syndrome (IBS) is a complex disorder clinically characterized by abdominal pain and altered bowel habit. Its pathogenetic mechanisms are still incompletely known; genes, psychosocial factors, changes in gastrointestinal motility and visceral hypersensitivity are traditionally thought to play a crucial r... | 18,924,450 |
[Assessment of implication of transcranial ultrasonography in the diagnostics of acute disturbances of cerebral blood circulation in adults]. | Implication of transcranial ultrasonography (TUS) in diagnostics of acute disturbances of cerebral blood circulation (ADCBC) was studied in 324 subjects, aged from 20 to 83 years, including group I (208 subjects without neurological disturbances), group II (56 subjects without the structural intracranial changes which,... | 18,924,473 |
[The biomechanics of dental implants and dentures]. | Osseointegrated implants are actually replacements for natural teeth, and, like natural teeth, they are exposed to various forces. Rejection and bad osseointegration of implants rarely occur today because oral implants are made from biocompatible materials. Most complications are a consequence of badly planned implant ... | 18,924,477 |
[Endoscopic augmentation of neurogenic bladder with botulinum-A toxin in children]. | To present our experience with endoscopic intradetrusor injections of botulinum-A toxin. Endoscopic treatment was proposed for children in which no improvement or side effects were observed. Botulinum-A toxin was injected in 25 children 3 to 7 years old. All children were evaluated with voiding-charts, in all of them u... | 18,924,493 |
[Usefulness of Pak's test in Stapleton's modification in diagnosis of hypercalciuria in children]. | Recognition of the type of hypercalciuria in children in Pak's test in Stapleton's modification was performed. 26 children with hypercalciuria was enrolled to the study. 15/26 had positive family history. In all Pak's test in Stapleton's modification was done, blond tests of renal function (urea, creatinine), calcium-p... | 18,924,500 |
[Urinary tract infections--pediatric urologist point of view]. | Urinary tract infections (UTI) could present with different clinical forms dependent on intensity and localization of infection and child's age. The symptoms could be non specific in children. Condition that provoke to urinary stasis, especially voiding dysfunction is the favourable factor for UTI appearance. Gram-nega... | 18,924,514 |
[Reflux and obstructive nephropathy as a cause of renal failure in chronic dialysis children]. | We carried out a retrospective analysis of medical files to evaluate causes of chronic renal failure in 80 children (M--49, F--31), age 1 month to 20 years) who started renal replacement therapy in the Department of Nephrology and Dialysis of the Polish Mothers Memorial Hospital in the years 1990-2007. In 28 children (... | 18,924,517 |
[Program of early diagnosis of chronic renal disease in children--SopKard 15 nephrological project]. | The Sopot Program of Cardiac Infarct and Stroke Prevention--SopKard 1999-2009 was established for health promotion to decrease cardio-vascular diseases mortality. To serve these purposes a new project SopKard 15 for adolescents was created. The main aim of SopKard 15 is evaluation of health status with particular atten... | 18,924,519 |
[Kidney transplantation into a neurogenic bladder in myelomeningocele patient (MMC)]. | We report a 24-year-old patient with neurogenic bladder due to myelomeningocele (MMC) who received a kidney transplant without prior bladder reconstruction. Following transplantation recurrent episodes of febrile pyelonephritis were observed with elevations of creatinine. A year after Tx a bladder augmentation was perf... | 18,924,522 |
Breastfeeding, body mass index, asthma and atopy in children. | The objective of this study was to determine the relationship between breastfeeding, asthma and atopy, and any influence of child body mass index (BMI). Prospective birth cohort data were used to model the association between breastfeeding duration, BMI, asthma and atopy in children at six years. After adjustment for B... | 18,924,535 |
Ethnic differences in the BMI-%BF relationships between young Japanese and Australian-Caucasian males living in Australia using dual-energy X-ray absorptiometry. | The Body Mass Index (BMI) has been used worldwide as an indicator of fatness. However, the universal cut-off points by the World Health Organisation (WHO) classification may not be appropriate for every ethnic group when consider the relationship with their actual total body fatness (%BF). The application of population... | 18,924,538 |
Clinical presentation and diagnosis of acne: patient-centric considerations. | Acne is a common dermatologic condition that primarily affects adolescents and young adults. Advances in research have led to more in-depth understanding of the pathophysiology of this condition and the development of new therapeutic interventions. Acne is now recognized as a multifactorial disease requiring a multifac... | 18,924,542 |
Genetic opportunities for psychiatric epidemiology: on life stress and depression. | Genetics can offer new resources to epidemiology. This review will consider recent findings regarding the link between stress and depression as an example to illustrate the added value of employing genetics in epidemiological studies. Systematic review of medical and psychological databases. Genetic and environmental f... | 18,924,559 |
The metabolic implications of long term cannabis use in patients with psychosis. | The aim of this paper is to summarise the effects of cannabis use on appetite and energy balance, and to subsequently investigate the possible implications this may have in patients with psychosis, in whom a high prevalence of cannabis use has been reported. A narrative review based on the recent literature regarding c... | 18,924,561 |
Longitudinal differences and trends in body fat and running endurance in Hungarian primary schoolboys. | Long-range repeated-measure sample differences in body dimensions, body composition and physical performance are considered accurately describing the changes in a population's life standards and lifestyle. The aim of our study was to analyse such changes in longitudinal studies repeated after a 15-year interval. Two si... | 18,924,569 |
[High Frequency Jet Ventilation and laryngeal surgery, clinical practice]. | High Frequency Jet Ventilation is one in a group of alternative ventilatory techniques characterized by the application of small tidal volumes delivered at higher than physiological rates, followed by the passive expiration. There are two groups of indications: first, High Frequency Jet ventilation was used as a specia... | 18,924,593 |
ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. | Plasma HDL levels are inversely related to the incidence of atherosclerotic disease. Some of the atheroprotective effects of HDL are likely mediated via preservation of EC function. Whether the beneficial effects of HDL on ECs depend on its involvement in cholesterol efflux via the ATP-binding cassette transporters ABC... | 18,924,609 |
My continuing adventure with 21 CFR Part 11--the evolution of Zymark's compliance. | A renewed focus has been given to the 3-year-old regulation 21 CFR Part 11, Electronic Records and Electronic Signatures. This paper gives a chronology of the process of an equipment vendor, Zymark Corporation, validating laboratory automation equipment for compliance to the regulation 21 CFR Part 11. Zymark's Tablet P... | 18,924,710 |
New Developments in the Field of Reaction Technology: The Multiparallel Reactor HPMR 50-96. | Catalytic high-pressure reactions play an important role in classic bulk chemistry. The optimization of common reactions, the search for new and more effective catalysts, and the increasing use of catalytic pressure reactions in the field of drug development call for high-parallel reaction systems. A crucial task of cu... | 18,924,722 |
Evaluation of the Dimension XL clinical chemistry system. | The analytical performance of the Dimension XL clinical chemical system was evaluated. The XL is the latest addition to the Dimension family of instruments; it is a random access analyser with a throughput up to 740 tests/hour. Regression analysis of method comparison studies with Dimension AR yielded slopes of 0.93 to... | 18,924,790 |
An automatic system for determining the effects of temperature on the hysteresis curves of ion-selective electrodes. | This paper describes an automatic system which measures the effect of temperature variations on the response of ion-selective electrodes (hysteresis curves). The system is managed by a computer program which plots hysteresis curves following a pre-established temperature cycle, from setting and controlling the temperat... | 18,924,793 |
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