title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Thermally activated Peierls dimerization in ferromagnetic spin chains. | We demonstrate that a Peierls dimerization can occur in ferromagnetic spin chains activated by thermal fluctuations. The dimer order parameter and entanglement measures are studied as functions of the modulation of the magnetic exchange interaction and temperature, using a spin-wave theory and the density-matrix renorm... | 18,999,635 |
High-energy collision of two black holes. | We study the head-on collision of two highly boosted equal mass, nonrotating black holes. We determine the waveforms, radiated energies, and mode excitation in the center of mass frame for a variety of boosts. For the first time we are able to compare analytic calculations, black-hole perturbation theory, and strong fi... | 18,999,655 |
Next-to-next-to-leading order corrections to three-jet observables in electron-positron annihilation. | I report on a numerical program, which can be used to calculate any infrared safe three-jet observable in electron-positron annihilation to next-to-next-to-leading order in the strong coupling constant alpha(s). The results are compared to a recent calculation by another group. Numerical differences in three color fact... | 18,999,659 |
Onset of pi(0) suppression studied in Cu+Cu collisions at sqrt S NN=22.4, 62.4, and 200 GeV. | Neutral pion transverse momentum (p(T)) spectra at midrapidity (|y| less than or approximately 0.35) were measured in Cu+Cu collisions at sqrt[s(NN)]=22.4, 62.4, and 200 GeV. Relative to pi_(0) yields in p+p collisions scaled by the number of inelastic nucleon-nucleon collisions (N(coll) the pi_(0) yields for p(T) more... | 18,999,660 |
Resistive-wall-mode active rotation in the RFX-mod device. | The fundamental question of how the flow velocity of the background plasma can influence the motion of magnetohydrodynamics instabilities and, in the ultimate analysis, their stability is addressed. The growth of resistive-wall-mode instabilities in toroidal confinement devices well represents one example of such a pro... | 18,999,679 |
Time-dependent density-functional theory and strongly correlated systems: insight from numerical studies. | We illustrate the scope of time-dependent density-functional theory for strongly correlated (lattice) models out of equilibrium. Using the exact many-body time evolution, we reverse engineer the exact exchange correlation (xc) potential v_(xc) for small Hubbard chains exposed to time-dependent fields. We introduce an a... | 18,999,689 |
Zener polaron ordering variants induced by A-site ordering in half-doped manganites. | We have studied the magnetism of the half-doped charge ordered manganite YBaMn2O6. A formation of ferromagnetic plaquettes of four Mn atoms in the charge ordered phase below T_{CO} approximately 480 K is inferred from high temperature magnetic susceptibility data and the magnetic structure, as determined by neutron pow... | 18,999,692 |
Spin wave dispersion on the nanometer scale. | Hot electrons injected into antiferromagnetic Mn layers from the tip of a low temperature scanning tunneling microscope have been used to determine the energies, lifetimes, and momenta of antiferromagnetic spin waves on the nanometer scale. The spin waves show a linear dispersion with a velocity of 160+/-10 meV A and l... | 18,999,706 |
Inference from matrix products: a heuristic spin-glass algorithm. | We present an algorithm for finding ground states of two-dimensional spin-glass systems based on ideas from matrix product states in quantum information theory. The algorithm works directly at zero temperature and defines an approximation to the energy whose accuracy depends on a parameter k. We test the algorithm agai... | 18,999,711 |
Causality-based criteria for a negative refractive index must be used with care. | Using the principle of causality as expressed in the Kramers-Kronig relations, we derive a generalized criterion for a negative refractive index that admits imperfect transparency at an observation frequency omega. It also allows us to relate the global properties of the loss (i.e., its frequency response) to its local... | 18,999,712 |
Excitations of one-dimensional Bose-Einstein condensates in a random potential. | We examine bosons hopping on a one-dimensional lattice in the presence of a random potential at zero temperature. Bogoliubov excitations of the Bose-Einstein condensate formed under such conditions are localized, with the localization length diverging at low frequency as l(omega) approximately 1/omega(alpha). We show t... | 18,999,729 |
Evolution of entanglement between distinguishable light states. | We investigate the evolution of quantum correlations over the lifetime of a multiphoton state. Measurements reveal time-dependent oscillations of the entanglement fidelity for photon pairs created by a single semiconductor quantum dot. The oscillations are attributed to the phase acquired in the intermediate, nondegene... | 18,999,730 |
Variable-range projection model for turbulence-driven collisions. | We discuss the relative speeds DeltaV of inertial particles suspended in a highly turbulent gas when the Stokes number, a dimensionless measure of their inertia, is large. We identify a mechanism giving rise to the distribution P(DeltaV) approximately exp(-C|DeltaV|(4/3)) (for some constant C). Our conclusions are supp... | 18,999,752 |
Unconventional quasiparticle lifetime in graphene. | We address the question of how large can the lifetime of electronic states be at low energies in graphene, below the scale of the optical phonon modes. For this purpose, we study the many-body effects at the K point of the spectrum, which induce a strong coupling between electron-hole pairs and out-of-plane phonons. We... | 18,999,770 |
Generalized Elliott-Yafet theory of electron spin relaxation in metals: origin of the anomalous electron spin lifetime in MgB2. | The temperature dependence of the electron-spin relaxation time in MgB2 is anomalous as it does not follow the resistivity above 150 K; it has a maximum around 400 K and decreases for higher temperatures. This violates the well established Elliot-Yafet theory of spin relaxation in metals. The anomaly occurs when the qu... | 18,999,776 |
K-doping dependence of the Fermi surface of the iron-arsenic Ba1-xKxFe2As2 superconductor using angle-resolved photoemission spectroscopy. | We use angle-resolved photoemission spectroscopy to investigate the electronic properties of the newly discovered iron-arsenic superconductor Ba_(1-x)K_(x)Fe_(2)As_(2) and nonsuperconducting BaFe_(2)As_(2). Our study indicates that the Fermi surface of the undoped, parent compound BaFe_(2)As_(2) consists of hole pocket... | 18,999,778 |
Role of reversibility in viral capsid growth: a paradigm for self-assembly. | Self-assembly at submicroscopic scales is an important but little understood phenomenon. A prominent example is virus capsid growth, whose underlying behavior can be modeled using simple particles that assemble into polyhedral shells. Molecular dynamics simulation of shell formation in the presence of an atomistic solv... | 18,999,841 |
Spin states of holes in Ge/Si nanowire quantum dots. | We investigate tunable hole quantum dots defined by surface gating Ge/Si core-shell nanowire heterostructures. In single level Coulomb-blockade transport measurements at low temperatures spin doublets are found, which become sequentially filled by holes. Magnetotransport measurements allow us to extract a g factor g ap... | 18,999,847 |
Frustration, area law, and interference in quantum spin models. | We study frustrated quantum systems from a quantum information perspective. Within this approach, we find that highly frustrated systems do not follow any general "area law" of block entanglement, while weakly frustrated ones have area laws similar to those of nonfrustrated systems away from criticality. To calculate t... | 18,999,858 |
Continuous paranematic-to-nematic ordering transitions of liquid crystals in tubular silica nanochannels. | The optical birefringence of rodlike nematogens (7CB, 8CB), imbibed in parallel silica channels with 10 nm diameter and 300 microm length, is measured and compared to the thermotropic bulk behavior. The orientational order of the confined liquid crystals, quantified by the uniaxial nematic ordering parameter, evolves c... | 18,999,865 |
Presence of serum carbonic anhydrase autoantibodies in patients relapsed after autologous stem cell transplantation indicates an improved prognosis. | Here we report patients with Hodgkin's disease and multiple myeloma, who relapsed/progressed after high dose therapy and autologous stem cell transplantation. In patients who developed aplastic anemia type syndrome, spontaneous tumor regression was observed and concomitantly high titers of serum autoantibodies were fou... | 18,999,876 |
Prognosis in hormon receptor negative breast cancer patients according to ERBB2 status. | Breast carcinomas represent a heterogenous group of tumors and recent studies have demonstrated several subtypes of breast cancer by gene expression profiles. This study aimed to compare hormon receptor negative (ER-/PR-/ERBB2+) and triple negative (ER-/PR-/ERBB2-) patients in terms of prognosis and to show that molecu... | 18,999,885 |
Evaluation of two gene-silencing constructs for resistance to tomato yellow leaf curl viruses in Nicotiana benthamiana plants. | Infiltration of Agrobacterium tumefaciens into intact plant leaves of N. benthamiana was used to test the efficiency of two virus-based silencing constructs conferring resistance to the closely related begomoviruses. The constructs contained the most conserved sequences of the coat protein (CP) gene and replication-ass... | 18,999,888 |
Information and consent in internet paternity testing: focus on minors' protection in Italy. | Paternity testing in Italy is usually performed by private laboratories and universities having direct contacts with the applicants. Recently, the number of paternity tests offered through laboratory websites has increased in Italy and Europe. The execution of genetic tests, including paternity testing based on DNA ana... | 18,999,916 |
Prenatal diagnosis: update on invasive versus noninvasive fetal diagnostic testing from maternal blood. | The modern obstetrics care includes noninvasive prenatal diagnosis testing such as first trimester screening performed between 11 and 14 weeks' gestation and second trimester screening performed between 15 and 20 weeks. In these screening tests, biochemical markers are measured in the maternal blood with or without ult... | 18,999,924 |
High expression of circadian gene mPer2 diminishes radiosensitivity of tumor cells. | The aim of this study was to study mPeriod2 gene expression influencing the radiosensitivity of mouse tumor cells exposed to 60Co-gamma-rays. Lewis lung carcinoma (LLC) and EMT6 cells were induced by phorbol myristate acetate or transfected with pcDNA3.1-mPer2 and irradiated with 60Co-gamma-rays, then analyzed with sev... | 18,999,929 |
Cetuximab: preclinical evaluation of a monoclonal antibody targeting EGFR for radioimmunodiagnostic and radioimmunotherapeutic applications. | The monoclonal antibody, cetuximab, binds to epidermal growth-factor receptor and thus provides an opportunity to create both imaging and therapies that target this receptor. The potential of cetuximab as a radioimmunoconjugate, using the acyclic bifunctional chelator, CHX-A"-DTPA, was investigated. The pharmacokinetic... | 18,999,934 |
A virtual reality environment for patient data visualization and endoscopic surgical planning. | Visualizing patient data in a three-dimensional (3D) representation can be an effective surgical planning tool.As medical imaging technologies improve with faster and higher resolution scans, the use of virtual reality for interacting with medical images adds another level of realism to a 3D representation. The softwar... | 18,999,974 |
Surgical performance with head-mounted displays in laparoscopic surgery. | The difficulties of laparoscopic surgery include two-dimensional image projection and loss of alignment between the surgeon's hands and visual field. Head-mounted displays (HMDs) allow freedom from gazing at a stationary overhead monitor, thus improving ergonomics. Modern HMDs offer greatly improved image quality and r... | 18,999,982 |
Sixty years of nuclear moments. | In keeping with the tradition of prefatory articles for the Annual Review of Physical Chemistry, this is an autobiographical essay describing my scientific career. I begin with my background and education at Dartmouth and Caltech and follow with my half-century of research and teaching at MIT. I emphasize subjects that... | 18,999,988 |
The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase. | We recently reported that the antineoplastic thiodioxopiperazine natural product chaetocin potently induces cellular oxidative stress, thus selectively killing cancer cells. In pursuit of underlying molecular mechanisms, we now report that chaetocin is a competitive and selective substrate for the oxidative stress miti... | 18,999,987 |
Ultrafast dynamics in reverse micelles. | Recent advances in ultrafast laser technology have spurred investigations of microheterogeneous solutions. In particular, researchers have explored details of reverse micelles (RMs), which present isolated droplets of polar solvent sequestered from a continuous nonpolar phase by a surfactant layer. This review explores... | 18,999,990 |
Principles and progress in ultrafast multidimensional nuclear magnetic resonance. | Multidimensional acquisitions play a central role in the progress and applications of nuclear magnetic resonance (NMR) spectroscopy. Such experiments have been collected traditionally as an array of one-dimensional scans, with suitably incremented delay parameters that encode along independent temporal domains the nD s... | 18,999,994 |
Current research in preterm birth. | Preterm birth is one of the leading causes of infant mortality and the leading cause of infant morbidity in the United States. It accounts for >70% of neonatal deaths and almost half of long-term neurological disabilities. The Centers for Disease Control and Prevention (CDC) is collaborating with state health depart... | 19,000,029 |
Polish medical students' perceptions of the nursing profession: a cross-sectional study. | This study explored perceptions of the nursing profession held by medical students in Poland. Specifically, this study aimed to: (i) elicit medical students' opinions about the nursing profession; (ii) identify what skills and abilities they perceive as important for nurses and (iii) ascertain what nursing functions ar... | 19,000,084 |
Exercising impressive impressions: the exercise stereotype in male targets. | The main purpose of this study was to investigate the exercise stereotype and the non-exerciser stereotype on male targets, and the moderating effects of impression motivation in 184 female and 73 male Swedish undergraduate students. The participants read a description of one of the following male targets: a typical ex... | 19,000,098 |
Mouth rinse but not ingestion of a carbohydrate solution improves 1-h cycle time trial performance. | The aim of the present study was to further explore the influence of ingestion and mouth rinse with a carbohydrate-electrolyte solution (CES) on the performance during a approximately 1 h high-intensity time trial on trained subjects. Subjects rinsed around the mouth or ingested a 6% isotonic CES or placebo (14 mL/kg b... | 19,000,099 |
Do anthropometric and fitness characteristics vary according to birth date distribution in elite youth academy soccer players? | We examined whether maturity, anthropometric profiles and fitness measures vary according to birth date distribution in elite, under-14 youth academy soccer players. The selection year was divided into four quarters, with 160 male players grouped according to individual birth date. Players had their skeletal age determ... | 19,000,100 |
Identification of a new HLA DRB1 allele (HLA-DRB1*1167) in a potential hematopoietic stem cell donor from Iraqi Kurdistan. | High-resolution polymerase chain reaction sequence-specific primer typing and sequence-based typing of the human leukocyte antigen (HLA) gene DRB1 in a potential hematopoietic stem cell donor of Kurdish ethnicity revealed a new allelic variant of HLA-DRB1*11. The sequence was named DRB1*1167, and comparison with previo... | 19,000,134 |
Structural aspects of B*4617 molecule, a novel HLA-B*46 allele identified by sequence-based typing. | New allele B*4617 showed one nucleotide difference with B*460101 at codon 167 (TGG-->TCG). | 19,000,137 |
Genetic association between functional haplotype of collagen type III alpha 1 and chronic hepatitis B and cirrhosis in Koreans. | Collagen type III alpha 1 (COL3A1) is one of the extracelluar matrix (ECM) proteins. The expression of COL3A1 is closely related to chronic liver diseases. In this study, we investigated whether single nucleotide polymorphisms (SNPs) of COL3A1 confer genetic susceptibility to patients with hepatitis B virus-infected li... | 19,000,145 |
Unusual presentation of Ramsay Hunt syndrome in renal transplant patients: case report and literature review. | Ramsay Hunt syndrome (RHS) is a rare manifestation of varicella zoster virus (VZV) infection that accounts for around 12% of all cases of facial paralysis. Although it is more common in immunosuppressed individuals, it has not been yet reported in kidney transplant recipients. We describe the case of a 41-year-old man ... | 19,000,154 |
VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. | VH1/BRL2 is a receptor-like kinase of the BRI1 family with a role in vascular development. In developing Arabidopsis leaves it is expressed first in ground cells and then becomes restricted to provascular and procambial cells as venation forms. We isolated proteins interacting with the activated (phosphorylated) cytopl... | 19,000,166 |
Arabidopsis mitogen-activated protein kinase MPK12 interacts with the MAPK phosphatase IBR5 and regulates auxin signaling. | Mitogen-activated protein kinase (MAPK) phosphatases are important negative regulators in the MAPK signaling pathways responsible for many essential processes in plants, including development, stress management and hormonal responses. A mutation in INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5), which is predicted to encode a ... | 19,000,167 |
Efficacy of topical PUVA soaks for palmoplantar dermatoses: an audit. | With a lack of evidence base for individual topical PUVA protocols, treatment is presently based on the consensus of current practice. This audit was designed to investigate the effectiveness of topical PUVA for palmoplantar dermatoses. Phototherapy notes were reviewed on all patients who received hand and/or foot PUVA... | 19,000,183 |
Evidence-based outcomes in pain research and clinical practice. | The growing emphasis on evidence-based medicine dictates that reliable, evidence-based outcomes be utilized in documenting response to treatment, as well as determining the treatment efficacy and cost-effectiveness of different treatment modalities. The biopsychosocial model conceptualizes pain as a complex multifactor... | 19,000,173 |
RcDhn5, a cold acclimation-responsive dehydrin from Rhododendron catawbiense rescues enzyme activity from dehydration effects in vitro and enhances freezing tolerance in RcDhn5-overexpressing Arabidopsis plants. | Dehydrins (DHNs) are typically induced in response to abiotic stresses that impose cellular dehydration. As extracellular freezing results in cellular dehydration, accumulation of DHNs and development of desiccation tolerance are believed to be key components of the cold acclimation (CA) process. The present study show... | 19,000,195 |
The devil you know: neuroticism predicts neural response to uncertainty. | Individuals differ in the extent to which they respond negatively to uncertainty. Although some individuals feel little discomfort when facing the unknown, those high in neuroticism find it aversive. We examined neurophysiological responses to uncertainty using an event-related potential framework. Participants complet... | 19,000,202 |
Black + white = black: hypodescent in reflexive categorization of racially ambiguous faces. | Historically, the principle of hypodescent specified that individuals with one Black and one White parent should be considered Black. Two experiments examined whether categorizations of racially ambiguous targets reflect this principle. Participants studied ambiguous target faces accompanied by profiles that either did... | 19,000,204 |
Which thoughts count? Algorithms for evaluating satisfaction in relationships. | Individuals differ in both their motivation to obtain incentives in their relationships (approach goals) and their motivation to dampen the threats in their relationships (avoidance goals). When evaluating relationship satisfaction, individuals with strong approach goals should weigh positive features in their relation... | 19,000,214 |
Effect of weaning to oestrus interval and equine chorionic gonadotropin on vaginal electrical impedance during peri-oestrus in sows. | The influence of weaning to oestrus interval, its interaction with parity and equine chorionic gonadotropin (eCG) on changes of vaginal impedance in sows after weaning was examined. The impedance measurements were carried out by a four-terminal method. Sows were monitored for oestrus via exposure to a sexually mature b... | 19,000,219 |
Physical activity and healthy eating in the after-school environment. | No research to date has extensively described moderate and vigorous physical activity (MVPA) and healthful eating (HE) opportunities in the after-school environment. The current study described the quality of the after-school environment for its impact on children's MVPA and HE. An alliance of 7 elementary schools and ... | 19,000,239 |
Remission of diabetes mellitus in cats with diabetic ketoacidosis. | Diabetic ketoacidosis (DKA) has long been considered a key clinical feature of type-1 diabetes mellitus (DM) in humans although. An increasing number of cases of ketoacidosis have been reported in people with type-2 DM. Cats initially diagnosed with DKA can achieve remission from diabetes. Cats with DKA and diabetic re... | 19,000,245 |
Phase I dose escalation of single-agent vinblastine in dogs. | Vinblastine (VBL) is commonly used in dogs at a dosage of 2.0 mg/m2. The minimal toxicity observed at this dosage indicates that higher dosages might be well tolerated. The maximum tolerated dosage (MTD) for a single VBL treatment is higher than the previously published dosage of 2.0 mg/m2. Twenty-three dogs with lymph... | 19,000,250 |
Disposition and safety of zonisamide after intravenous and oral single dose and oral multiple dosing in normal hound dogs. | The purpose of this study was to determine an oral dosing regimen of zonisamide in healthy dogs such that therapeutic concentrations would be safely reached and maintained at steady-state. Adult hound dogs (n = 8) received a single IV (6.9) and an oral (PO) dose (10.3 mg/kg) using a randomized cross-over design. Zonisa... | 19,000,278 |
Milk feeding and dietary patterns predict weight and fat gains in infancy. | Current guidelines recommend that infants are exclusively breast fed for the first 6 months of life, with particular solid foods being gradually introduced from 6 months. Our objective was to compare the growth of infants whose feeding most closely followed current guidelines with the growth of infants with other feedi... | 19,000,296 |
Assays with lower detection limits: implications for epidemiological investigations. | Epidemiological investigations of health effects related to chronic low-level exposures or other circumstances often face the difficult task of dealing with levels of biomarkers that are hard to detect and/or quantify. In these cases instrumentation may not adequately measure biomarker levels. Reasons include a failure... | 19,000,298 |
Mental health of refugees following state-sponsored repatriation from Germany. | In recent years, Voluntary Assisted Return Programmes (VARPs) have received increasing funding as a potential way of reducing the number of refugees in EU member states. A number of factors may affect the mental well-being of returnees. These include adjustment to the home country following return, difficult living con... | 19,000,300 |
Timing of supplementation of selenium and isoflavones determines prostate cancer risk factor reduction in rats. | High dietary intake of selenium or isoflavones reduces risk factors for prostate cancer. We tested whether combined supplementation of these two dietary components would reduce prostate cancer risk factors in rats more than supplementation of each component individually. Male Noble rat pups were exposed from conception... | 19,000,315 |
Large vestibular aqueduct syndrome and endolymphatic hydrops: two presentations of a common primary inner-ear dysfunction? | To present the theory that large vestibular aqueduct syndrome (i.e. the recognised existence of an enlarged vestibular aqueduct with progressive sensorineural hearing loss) and endolymphatic hydrops are due to a common primary dysfunction of inner-ear fluid homeostasis. Case report and review of the world literature co... | 19,000,343 |
Effects of intestinal constituents and lipids on intestinal formation and pharmacokinetics of desethylamiodarone formed from amiodarone. | To model the impact of intestinal components associated with a high fat meal on metabolism of amiodarone, rat everted intestinal sacs were evaluated for their ability to metabolize the drug to its active metabolite (desethylamiodarone) under a variety of conditions. The preparations were obtained from fasted rats or ra... | 19,000,367 |
Modulating effect of polyethylene glycol on the intestinal transport and absorption of prednisolone, methylprednisolone and quinidine in rats by in-vitro and in-situ absorption studies. | The effects of polyethylene glycol 20000 (PEG 20000) on the intestinal absorption of prednisolone, methylprednisolone and quinidine, three P-glycoprotein (P-gp) substrates, across the isolated rat intestinal membranes were examined by an in-vitro diffusion chamber system. The serosal-to-mucosal (secretory) transport of... | 19,000,368 |
The effect of high glucose on SERT, the human plasmalemmal serotonin transporter. | The aim of this work was to investigate the effect of short- and long-term high-glucose exposure on the plasmalemmal serotonin transporter (SERT)-mediated uptake of [(3)H]-serotonin (5-HT) by Caco-2 cells. Short-term exposure of Caco-2 cells to high apical glucose levels (30 mM for 2 h or 40 mM for 1 h) decreased the u... | 19,000,377 |
Protein malnutrition and aging affects entraining and intensity of locomotor activity and body temperature circadian rhythms in rats. | Independently, chronic protein malnutrition and aging have been shown to affect locomotor activity (LA) and body temperature (BT) rhythms in mammals. The objective of the present study was to ascertain the combined effects of these two factors by examining period, entrainment and other circadian parameters between LA a... | 19,000,379 |
Cost-effectiveness of magnetic resonance imaging of the knee for patients presenting in primary care. | Musculoskeletal problems generate high costs. Of these disorders, patients with knee problems are commonly seen by GPs. Magnetic resonance imaging (MRI) of the knee is an accurate diagnostic test, but there is uncertainty as to whether GP access to MRI for these patients is a cost-effective policy. To investigate the c... | 19,000,394 |
[Application of multicolor fluorescence in situ hybridization to early diagnosis of esophageal squamous cell carcinoma]. | Detection of chromosome aberrations has been applied to diagnose some tumors. However, there are no chromosomal markers for the diagnosis of esophageal carcinoma so far. This study was to analyze aberrations of some chromosomes in esophageal squamous cell carcinoma (ESCC) and its premalignant lesions, thus to explore t... | 19,000,442 |
[Correlation of cell cycle alteration to SOCS-1 gene demethylation induced by arsenic trioxide in myeloma cell lines]. | Recent studies suggest strong therapeutic potentials of arsenic trioxide (As2O3) for multiple myeloma(MM), which may be due to As2O3-induced demethylation of tumor suppressor genes. This study was to explore the correlation of cell cycle alteration to SOCS-1 gene demethylation after As2O3 induction in MM cell lines in ... | 19,000,444 |
[Expression of TNF-like weak inducer of apoptosis (TWEAK) and its relationship to microvessel density in breast cancer]. | The expression of TNF-like weak inducer of apoptosis (TWEAK) in breast cancer remains disputable. This study was to investigate the expression of TWEAK in breast cancer tissues and breast cancer cell lines with different invasive abilities, and the relationship of TWEAK with microvessel density (MVD). Immunohistochemic... | 19,000,449 |
[Efficacy of GDP regimen (gemcitabine, dexamethasone, and cisplatin) on relapsed or refractory aggressive non-Hodgkin's Lymphoma: a report of 24 cases]. | The prognosis of relapsed or refractory aggressive non-Hodgkin's lymphoma (NHL) after front-line therapy remains poor. The development of more effective and less toxic salvage regimens remains a major challenge. Gemcitabine is effective in treating lymphoma and, when combined with cisplatin, is effective for some solid... | 19,000,458 |
[Epidemiology of drug poisoning in the Ramón y Cajal University Hospital during a year]. | In recent years, there has been an increase of drugs poisoning cases seen in the Emergency Department. This study has aimed to evaluate the characteristics of these cases in the Ramón and Cajal Hospital in Madrid. A descriptive analysis about the drug poisonings diagnosed in 2004 was performed, using a retrospective se... | 19,000,470 |
[New CCR5 inhibitor antiretroviral drugs and integrase inhibitors]. | Two new antiretroviral drugs belonging to a new drug family have recently been marketed in Spain. These are maraviroc (CCR5 correceptor inhibitor) and raltegravir (integrase inhibitor). These have the advantage of not presenting crossed resistance with other previously administered antiretroviral drugs, converting them... | 19,000,475 |
[Effect of the location of previous atherosclerotic disease on prognosis in diabetic patients. The Barbanza Diabetes Study]. | To assess the effect of different forms of atherosclerotic disease on prognosis in diabetic patients. This multicenter prospective cohort study involved 1423 consecutive patients with diabetes mellitus who were recruited by 31 primary care physicians. The patients' characteristics were recorded and they were followed u... | 19,000,492 |
[Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease: data from the Spanish patient registry]. | Among the idiopathic interstitial lung diseases, respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) and desquamative interstitial pneumonia (DIP) make up a subgroup of rare diseases that are clearly smoking related. Few large case series have been published. We describe 19 cases registered in Spain... | 19,000,514 |
[Spirometric evaluation of respiratory involvement in asymptomatic multinodular goiter with an intrathoracic component]. | Respiratory tract obstruction is underestimated in asymptomatic intrathoracic goiter. Our aim was to evaluate the involvement of the upper airway of asymptomatic patients with intrathoracic multinodular goiter, assessing the effect on respiratory function by means of spirometry. We selected 21 patients with asymptomati... | 19,000,515 |
Additional renoprotective effects of azelnidipine combined with angiotensin receptor blockers in patients with diabetic nephropathy. | Azelnidipine has been reported to have antioxidant effects and attenuates tubulointerstitial ischemia. The aim of the present study was to determine whether azelnidipine exerts additional renoprotective effects to angiotensin II receptor blockers (ARBs) in hypertensive patients with diabetic nephropathy and microalbumi... | 19,000,538 |
Multicenter prospective randomized, double-blind comparative study between lanthanum carbonate and calcium carbonate as phosphate binders in Japanese hemodialysis patients with hyperphosphatemia. | The efficacy of lanthanum carbonate as a phosphate binder for the treatment of hyperphosphatemia has been reported, but not from a double-blind, comparator-controlled comparative study. The safety and efficacy of lanthanum carbonate and calcium carbonate on serum phosphate and calcium levels in Japanese hemodialysis pa... | 19,000,540 |
Subjective sleep efficiency of hemodialysis patients. | Sleep disturbances have a major influence on quality of life. A commonly used measure of sleep disturbances is sleep efficiency. The purpose of this study was to investigate the prevalence of decreased subjective sleep efficiency in hemodialysis patients. An additional goal was to identify clinical, dialysis or laborat... | 19,000,541 |
Zotepine-induced spontaneous ejaculation. | A man with schizophrenia received regular haloperidol ester therapy, but his psychotic symptoms were not mitigated. A combination of zotepine and haloperidol was then used to relieve the psychotic symptoms. However, the patient developed spontaneous ejaculations, which occurred many times a day while undergoing haloper... | 19,000,555 |
Large outbreaks of Salmonella Typhimurium infection in Denmark in 2008. | An outbreak of Salmonella Typhimurium phage type U292 has been ongoing in Denmark since 1 April, with 1,054 cases registered until 23 October 2008. Extensive investigations including hypothesis-generating interviews, matched case-control studies, cohort studies in embedded outbreaks, shopping list analyses, analyses of... | 19,000,563 |
Anti-cockroach and anti-mouse IgE are associated with early wheeze and atopy in an inner-city birth cohort. | The relationships between cockroach and mouse allergen exposure, anti-cockroach and anti-mouse IgE, and wheeze, rhinitis, and atopic dermatitis in children as young as age 3 years are of public health importance but have not been thoroughly evaluated. We hypothesized that inner-city children might have anti-cockroach a... | 19,000,580 |
Complications of arteriovenous hemodialysis access: recognition and management. | English language citations reporting complications of arteriovenous access for hemodialysis are critically reviewed and discussed. Venous hypertension, arterial steal syndrome, and high-output cardiac failure occur as a result of hemodynamic alterations potentiated by access flow. Uremic and diabetic neuropathies are c... | 19,000,594 |
Chemical characteristics and volatile profile of genetically modified peanut cultivars. | Genetic engineering has been used to modify peanut cultivars for improving agronomic performance and pest resistance. Food products developed through genetic engineering have to be assessed for their safety before approval for human consumption. Preservation of desirable chemical, flavor and aroma attributes of the pea... | 19,000,610 |
Utilization of fermented barley extract obtained from a by-product of barley shochu for nisin production. | Fermented barley extract (FBE) obtained from a barley shochu by-product (shochu kasu) and its ethanol fractions were evaluated as a medium and supplement, respectively, for nisin A production by Lactococcus lactis subsp. lactis ATCC 11454. A Brix 2.5 FBE medium supplemented with glucose provided a high level of nisin A... | 19,000,617 |
Amyotrophic lateral sclerosis linked to a novel SOD1 mutation with muscle mitochondrial dysfunction. | Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative motor neuron disorder. Mutations in Cu,Zn superoxide dismutase (SOD1) cause approximately 20% of familial ALS. One of the possible mechanisms whereby they induce disease is mitochondrial dysfunction in motor neurons. Here we describe a patient with ALS an... | 19,000,626 |
Development of CoMFA and CoMSIA models of cytotoxicity data of anti-HIV-1-phenylamino-1H-imidazole derivatives. | 3D-QSAR models of 1-Phenylamino-1H-imidazole derivatives with cytotoxic potential have been developed using CoMFA and CoMSIA. Models were built keeping both 10% and 25% of molecules in test set. The Database and Field-Fit alignments were used for CoMFA model development. The best QSAR model was obtained from CoMFA anal... | 19,000,644 |
Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cells. | HIV protease inhibitors are currently being discussed to be useful as new and alternative anti-cancer agents, especially as second line treatments for chemo-resistant human cancer types. Among three clinically applied HIV protease inhibitors tested, we found a high efficacy of nelfinavir on ovarian cancer cells, accomp... | 19,000,651 |
Tissue slices for the evaluation of metabolism-based toxicity with the example of diclofenac. | Drug-induced organ injury is a multifaceted process, involving numerous cell types and mediators, and remains a significant safety issue in pharmaceutical development and clinical therapy. Organotypic in vitro models, including precision-cut tissue slices, possess the multi-cellular, structural and functional features ... | 19,000,659 |
Chromogranin A and C-terminal endothelin-1 precursor fragment add independent prognostic information to amino-terminal proBNP in patients with acute destabilized heart failure. | The aim of this study was to evaluate the prognostic value of chromogranin A (CgA) and C-terminal endothelin-1 precursor fragment (CT-proET-1) in patients with acute destabilized heart failure. 137 consecutive patients with acute destabilized heart failure attending the emergency department of a tertiary care hospital ... | 19,000,665 |
Progesterone receptor in the forebrain of female gray short-tailed opossums: effects of exposure to male stimuli. | Progesterone receptor immunoreactivity (PRir) in brain areas involved in reproductive behavior in eutherian species was examined for the first time in a female marsupial, the gray short-tailed opossum (Monodelphis domestica, hereinafter, opossum). PRir in nuclei of neurons, measured as area covered by stained nuclei, w... | 19,000,689 |
A multiplexed immunoassay for detection of antibodies against avian influenza virus. | Avian influenza (AI) is a highly contagious disease in poultry and outbreaks can have dramatic economic and health implications. For effective disease surveillance, rapid and sensitive assays are needed to detect antibodies against AI virus (AIV) proteins. In this study, we report the development of a multiplexed fluor... | 19,000,692 |
Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: a validation study. | Transdermal nicotine is widely used for smoking cessation, but only approximately 20% of smokers quit successfully with this medication. Interindividual variability in nicotine metabolism rate may influence treatment response. This study sought to validate, and extend in a larger sample, our previous finding that the r... | 19,000,709 |
No interaction of body mass index and smoking on diabetes mellitus risk in elderly women. | We sought to assess the interaction of smoking and body mass index (BMI) on diabetes risk. We analyzed data from a community-based prospective cohort of 41,836 women from Iowa who completed a baseline survey in 1986 and five subsequent surveys through 2004. The final analysis included 36,839 participants. At baseline (... | 19,000,710 |
Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology. | Alpha7 nicotinic acetylcholine receptor channels are important ligand-gated ion channels that are fast desensitizing, cation selective and have been implicated in the pathophysiology of schizophrenia and Alzheimer's disease. We report here high quality alpha7 parallel patch clamp recordings using the QPatch automated p... | 19,000,713 |
Ephedra sinica inhibits complement activation and improves the motor functions after spinal cord injury in rats. | The activation of complement system has been known as an important and significant reaction against the secondary injury after spinal cord injury (SCI). In the present study, we investigated the effect of Ephedra sinica to the inflammation or complement system of injured spinal cord and the influence to the functional ... | 19,000,748 |
Antibodies for the treatment of bacterial infections: current experience and future prospects. | Antibodies can be used for the prevention and treatment of bacterial infections in animal models of disease. Current antibody technology allows the generation of high affinity human/humanized antibodies that can be optimized for antibacterial activity and in vivo biodistribution and pharmacokinetics. Such antibodies ha... | 19,000,762 |
A review of the current use of rituximab in autoimmune diseases. | Rituximab is a human/murine chimeric monoclonal antibody primarily used for treating non-Hodgkin's B-cell lymphoma. Recently it has also been used in the treatment of several autoimmune diseases. A literature review was conducted to determine the efficacy of rituximab in the treatment of some of these autoimmune diseas... | 19,000,786 |
Evolutionary biology: microsporidia sex--a missing link to fungi. | The evolutionary origins of the microsporidia, a group of intracellular eukaryotic pathogens, have been unclear. Genome analysis of a sex locus and other gene clusters has now revealed conserved synteny with zygomycete fungi, indicating that microsporidia are true fungi descended from a zygomycete ancestor. | 19,000,798 |
Evolutionary biology: patchy food may maintain a foraging polymorphism. | Two naturally-occurring alleles in the nematode Caenorhabditis elegans that differ by a single amino acid and cause striking differences in foraging behavior are probably maintained by selection in patchy environments. | 19,000,800 |
Social evolution: this microbe will self-destruct. | Phenotypic noise and social evolution in microbes have recently attracted huge interdisciplinary interest. A new study highlights the interaction between these phenomena and its implications for self-destructive cooperation. | 19,000,802 |
Structure of the kinesin13-microtubule ring complex. | To investigate the mechanism of kinesin13-induced microtubule depolymerization, we have calculated a three-dimensional (3D) map of the kinesin13-microtubule ring complex, using cryo-electron microscopy (cryo-EM) and image analysis. An atomic model of the complex was produced by docking the crystal structures of tubulin... | 19,000,825 |
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