title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Analysis of the distribution of spindle microtubules in the diatom Fragilaria. | The spindle of the colonial diatom Fragilaria contains two distinct sets of spindle microtubules (MTs): (a) MTs comprising the central spindle, which is composed of two half-spindles interdigitated to form a region of "overlap"; (b) MTs which radiate laterally from the poles. The central spindles from 28 cells are reco... | 365,870 | [
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Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy. | Indirect immunofluorescence microscopy was used to localize microfilament-associated proteins in the brush border of mouse intestinal epithelial cells. As expected, antibodies to actin decorated the microfilaments of the microvilli, giving rise to a very intense fluorescence. By contrast, antibodies to myosin, tropomyo... | 365,871 | [
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Presence of spectrin in untreated Friend erythroleukemic cells. Its accumulation upon treatment of the cells with dimethyl sulfoxide. | Friend leukemia cells (FLC) are nucleated erythroid precursors, and are markedly stimulated towards more advanced stages of differentiation by treatment with dimethyl sulfoxide (DMSO). The presence of spectrin, an erythrocyte membrane protein, has been investigated in untreated and in DMSO-treated FLC by indirect immun... | 365,872 | [
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Micromethod for biochemical identification of coagulase-negative staphylococci. | We have endeavored to elaborate a suitable method for easy and rapid identification in clinical microbiology laboratories of the different species of infection-inducing, coagulase-negative staphylococci. Ten type strains described by Kloos and Schleifer and 269 strains isolated from 95 patients were tested; the classic... | 365,879 | [
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Aerosolized terbutaline in asthmatics. Comparison of dosage strength, schedule, and method of administration. | Sixteen patients with bronchial asthma participated in three studies of inhaled terbutaline. Onset of action, duration, and peak effects were compared for a dose of 0.5 mg given in one, two, or four inhalations at 1 min intervals from a freon-propelled, metered-dose aerosol. There was no significant difference in the r... | 365,919 | [
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Immunohistochemical localization of thyroid hormone in rat thyroid gland. | Direct and indirect immunofluorescence techniques were used to localize the thyroid hormones triidothyronine (T3) and thyroxine (T4) in adult rat thyroid gland. Optimum dilutions of the antisera were established and four tissue fixatives were investigated for usefulness in this technique. Use of antibodies specific for... | 366,016 | [
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The capsules of Corynebacterium equi and Streptococcus equi. | The capsules of Corynebacterium equi and Streptococcus equi were examined by electron microscopy after staining with ruthenium red. They were compared with the capsule of Klebsiella pneumoniae which had previously been examined using the same procedure (Springer & Roth, 1973). The capsule of C. equi had a laminated... | 366,078 | [
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Early laminar excision: improved control of burn wound sepsis by partial dermatome debridement. | The large mass of devitalized tissue that comprises the burn eschar is gradually becoming recognized as the principal source of complications in the burn patient. Clinical observations suggest that the topical agent silver sulfadiazine does not penetrate the eschar sufficiently to prevent bacterial infection from becom... | 366,094 | [
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Gingival fluid flow after gingivectomy related to mechanical or chemical plaque control. | The effects of mechanical tooth cleaning and 0.2% chlorhexidine mouthrinses on healing after gingivectomy were compared in 8 patients by means of a "split mouth" technique. The experiment began after periodontal pack removal on day 7. Gingival fluid was sampled immediately before and on days 14, 21, 28, 35 after gingiv... | 366,098 | [
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The alteration of lingual mucosa with free gingival grafts. Protection of a denture bearing surface. | A technique has been described which has altered the form of denture bearing alveolar mucosa. Free gingival palatal grafts were used to create an attached gingival environment upon which removal denture prosthesis may rest. | 366,102 | [
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[On the history of the teaching of squint (author's transl)]. | After an introduction on the value of history also from modern medicine, the teaching of strabismus from the earliest begin at the time of Hammurapis (1700 BC) up to our times is broadly described. The old greek and latin ideas are analysed linguistically. The work of Johannes Müller and Emil Javel is especially emphas... | 366,256 | [
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[Results of Cüpper's "thread fixation" in squinters with inconstant angle (author's transl)]. | The results of strabismus operations on strabismus patients with variable angles are presented. The so-called "Fadenfixation" (Cüppers) is compared with the usual recess-resect method. Of the 62 cases of strabismus with variable angle which were operated without the "Fixation", only 3 cases were parallel post-operation... | 366,270 | [
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[Colonic suture technique: double-layer suture (author's transl)]. | A comparison of the results with single- and double-layer adapting sutures without general proximal colostomy shows no differences. This fact is supported by our experiences in 106 resections of the left half of the large bowel. | 366,311 | [
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Some features of the reaction of intracellular bacteriophages T1 to UV irradiation. | The reaction of complexes pf phage T1-cells of E. coli B or E. coli Bs-1 to UV irradiation was investigated. The complexes were irradiated at various stage of infection, and their survival, extent of Hcr and Phr, were evaluated. It was found that the UV resistance of phage DNA in the second half of the latent period fl... | 366,340 | [
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Practical considerations in gamma camera line spread function measurement. | In recent years the modulation transfer function (MTF) has played an important role in the quantitation of imaging performance of gamma cameras. The most common method of MTF determination requires line spread function (LSF) measurement. This paper reviews methods used for LSF measurements with special consideration gi... | 366,368 | [
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[Non-leukemic disease of the central nervous system in children with acute lymphoblastic leukemia. III. Subacute sclerosing panencephalitis (author's transl)]. | Diseases of the central nervous system (CNS) occurring during treatment of acute lymphoblastic leukemia (ALL) may be of leukemic or nonleukemic origin. Well known examples for CNS disease of nonleukemic origin are somnolence following prophylactic CNS irradiation, methotrexate-induced encephalopathy and acute infection... | 366,390 | [
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[The injured nose of the newborn. A review (author's transl)]. | In the newborn the following traumatic alterations of the nose can be seen: lesions of the soft tissues, flat noses (30--60%), damage by tubes, fixed nasal deformities (0.5%), treatable anterior septal dislocations (2--23%), and combined septal deformities (up to 50%). The literature of the last 100 years is reviewed a... | 366,393 | [
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Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli. | A screening procedure based on the formation of papillae on individual bacterial colonies was used to isolate mutants of Escherichia coli with high mutation rates in the presence of bromouracil. Most of the mutants obtained had high spontaneous mutation rates and mapped close to the previously known mutators mutT, mutS... | 366,396 | [
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[Presence of sexual forms (cleistothecia and Hülle cells) in a case of human maxillary sinus aspergillosis caused by Aspergillus nidulans in association with Aspergillus fumigatus]. | The authors observed, in a biopsic sample from a human maxillary sinus, the coexistence, in parasitic stages, of two different Aspergillus species: A. fumigatus and A. nidulans. After having described the morphologies of each species, in sections on slides, and particularly those of cleistothecia and Hülle-cells for th... | 366,429 | [
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Estradiol potentiation of hypothalamic uptake of LH-RH from the CSF. | Ovariectomized (Ovx) rats were treated (s.c.) with estradiol benzoate (E2B) for 7 days, and then 10, 25 or 100 ng LH-RH were microinjected into the 3rd ventricle. Intraventricular LH-RH elevated plasma LH at 10 and 30 min in a dose-response manner. In experiment 2, Ovx rats were treated with E2B or oil for 7 days and t... | 366,445 | [
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Therapeutic trial of tilorone in ALS: lack of benefit in a double-blind, placebo-controlled study. | Sixteen patients with amyotrophic lateral sclerosis (ALS) participated in a double-blind, placebo-controlled study using tilorone hydrochloride, a drug active against a variety of DNA and RNA viruses in animals. On the basis of neurologic examination, pulmonary function studies, quantitative muscle examination, speech ... | 366,454 | [
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[Anti-islet cell antibodies in insulin-dependent diabetics. Preliminary study]. | Anti-islet cell cytoplasm antibodies (ICA) were noted in the serum of insulin-dependent diabetics, but not in subjects with insulin-independent forms. These antibodies seem to represent an immunological marker for two forms of the disease, one in which ICA appears shortly after onset and later disappears, and another (... | 366,462 | [
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Vaginal flora in women undergoing hysterectomy with antibiotic prophylaxis. | One objection occasionally raised against the use of routine antibiotic prophylaxis for pelvic surgery is the concern that the flora of treated patients will be altered, thus favoring the emergence of different, potentially more resistant organisms. This report summarizes experience with 100 women undergoing elective h... | 366,484 | [
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Modified suturing contact lens for penetrating keratoplasty. | The authors have previously described a suturing contact lens that protects the corneal endothelium by aiding in the maintenance of the anterior chamber during penetrating keratoplasty. This report describes structural modifications of the suturing contact lens, which improve its stability and effectiveness. An additio... | 366,494 | [
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Median rhomboid glossitis: not a misnomer. Review of the literature and histologic study of twenty-eight cases. | A series of twenty-eight cases of median rhomboid glossitis were studied histologically. Of these twenty-eight cases, 85 percent showed fungal hyphae in the parakeratin layer. The literature is reviewed, and additional evidence is presented to support the theory the median rhomboid glossitis is not a developmental cond... | 366,496 | [
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[Mermithids as biological control agents of blackflies]. | About 80 species of mermithids parasitic in blackflies have been recorded from the Ethiopian and Holarctic regions. Species of three genera, Mesomermis, Gastromermis and Isomermis, are most common parasites of blackflies. Critical periods during the ontogenesis of all mermithids are associated with the penetration of i... | 366,523 | [
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Synthetic food colors and hyperactivity in children: a double-blind challenge experiment. | Nine hyperactive male subjects, selected on the basis of showing a favorable "response" to the Feingold diet in an earlier study, were maintained on a strict elimination (Feingold) diet for 11 weeks, and were given multiple trials of placebo and challenge food materials. Parental and teacher ratings, classroom behavior... | 366,539 | [
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Three-dimensional structure of thioredoxin induced by bacteriophage T4. | The three-dimensional structure of thioredoxin from bacteriophage T4 has been determined from a 2.8-angstrom resolution electron density map. Phase angles for this map were determined from one heavy atom derivative and anomalous differences from cadmium in the native crystals. The molecule of 87 amino acid residues is ... | 366,603 | [
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0.08871607,
0.08397823,
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0.2620124,
0.322489,
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Methionine analogs and cell division regulation in the yeast Saccharomyces cerevisiae. | Methionine analogs such as ethionine, selenomethionine, and trifluoromethionine all arrest growth and division of the yeast Saccharomyces cerevisiae. One analog, ethionine, caused cells of the yeast to arrest specifically within G1; reciprocal shift experiments showed that ethionine and alpha-factor arrested cells at t... | 366,609 | [
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Surface morphology of lymphoreticular cells: review of data obtained from scanning electron microscopy. | This illustrated review summarizes the current status of knowledge relating to the surface morphology of normal and malignant lymphocytes and other leukocytes, as seen by SEM, with particular emphasis on lymphoreticular disorders. Problems of interpretation of the SEM data and their significance are discussed. | 366,709 | [
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Detection of monoclonal B lymphocytes in multiple myeloma by immunofluorescence tests of surface immunoglobulins. | Peripheral blood lymphocytes of 16 patients with secretory type of multiple myeloma and 5 with nonmyelomatous monoclonal gammopathy were investigated for the surface immunoglobulins on the cell by immunofluorescence. A low pH shock of cells before staining was applied to dissociate the passively absorbed immunoglobulin... | 366,730 | [
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Total synthesis of a gene. | The method developed for the total synthesis of a given DNA containing biologically specific sequences consists of the following. The DNA in the double-stranded form is carefully divided into short single-stranded segments with suitable overlaps in the complementary strands. All the segments are chemically synthesized ... | 366,749 | [
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Emotional problems of the severely burned patient. | In this article we have tried to present an overview of some of the common emotional responses and problems seen in severely burned patients. We have suggested that first consideration be given to learning what sort of person the patient is and becoming familiar with what the burned patient experiences. General prevent... | 366,786 | [
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Closing the burn wound. | With recent advances in supportive therapy and surgical care, closure of the burn wound now can be accomplished earlier and more effectively than previously. Only by keeping the patient in a state of positive nitrogen balance, immunologically competent, and in equilibrium with the bacteria colonizing the burn wound can... | 366,787 | [
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[Investigations into the incidence of the various causative agents of mastitis in cattle. Studies done in the ambulatory clinic of the Faculty of Veterinary Medicine, Utrecht]. | The clinical and bacteriological findings in every head of cattle treated for clinical mastitis in the Ambulatory Clinic of the Veterinary Faculty of Utrecht University were recorded over a period of twelve months. Cattle affected with mastitis were classified into a number of groups, a classification based on the clin... | 366,794 | [
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Some aspects of epidemiology of resurgent malaria in Turkey. | The resurgence of autochthonous Plasmodium vivax malaria in Turkey is a matter of considerable concern. Anopheles sacharovi is the important vector but other species, notably A. superpictus, may play a role in transmission. The epidemiology is discussed in terms of factors related to the mosquito, factors related to th... | 366,812 | [
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Traffic of lymphocytes in the thoracic duct and renal lymph after allotransplantation and in immunosuppression. | A marked rise is seen in the number of white blood cells in the lymph leaving the sheep kidney after allografting; the number of lymphocytes leaving the kidney rising in direct relation to the degree of damage from acute rejection. No such rise is demonstrable in the number of lymphocytes in the thoracic duct lymph of ... | 366,821 | [
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The effects of hydrocortisone and dopamine on circulatory alterations in experimental acute endotoxin shock in dogs. | In our study of experimental endotoxin shock we tried therapeutic control of reversible acute endotoxin shock. In a standard model in the dog, in which endotoxin shock had been induced by intravenous injection of E. coli endotoxin dosed 1.75 mg/kg, the effects of hydrocortisone and dopamine administered concurrently we... | 366,935 | [
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[Differentiation by microimmunofluorescence of T. cruzi and T. cruzi-like strains from T. conorhini and T. rangeli, using protection from the sponge Aaptos papillata (author's transl)]. | Carbohydrates containing terminal nonreducting D N-acetylgalactosamin or D N-acetylglucosamin were identified at the cell surface of Trypanosoma cruzi by an indirect immunofluorescence test using the lectin of the sponge Aaptos papillata. With the method described in this study T. cruzi and T. cruzi-like strains are ea... | 366,941 | [
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[Electron microscopic studies on long-term perfused dog kidneys]. | In the applied preservation technique of kidneys used the fine-structural changes on main epithelial cells and glomeruli are relatively insignificant and appear reversible or reparable after a storage preservation up to 4 hours and permanent perfusion of 24 hours. After a storage preservation of 10 hours and an additio... | 366,971 | [
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[Diagnostic value of determining urinary fibrin split products in glomerulonephritis, pyelonephritis and graft rejection]. | On 112 patients with bioptically ascertained chronic proliferative glomerulonephritis, 94 with pyelonephritis and 23 patients with kidney transplantation altogether 1,050 times the fibrin fission products in the urine were estimated by the passive haemagglutination after Merskey. It was the aim of the investigation to ... | 366,978 | [
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[Multiple primary brain tumors]. | This is a write-up of 32 studies of patients suffering from multiple primary brain tumours. Such tumours are encountered quite rarely. Meningiomas, as well as their combination with tumours of another histological structure (neurinomas, gliomas) were most often studied among multiple primary brain tumours. Multiple gli... | 367,015 | [
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Phase contrast visualization of squamous cell microridges. | A successful attempt has been made to identify microridges on squamous cells in routine smears using phase contrast microscopy. Microridges may be identified on mature cells of buccal mucosa and in cervical smears, either alcohol or spray fixed, and even in smears up to five years old. The features identified with phas... | 367,027 | [
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Intracranial malignant lymphomas. A morphologic and immunocytologic study of twenty cases. | Fifteen primary intracranial reticulum cell sarcomas and five cases with an additional solitary extracranial tumor mass have been studied. For comparison, seven extracranial malignant non-Hodgkin lymphomas and normal lymphoid tissue were included. The methods used on formalin-fixed paraffin-embedded tissue sections wer... | 367,044 | [
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A recovered case of generalized BCG infection. | A female infant was at the age of 8 months admitted with muco-cutaneous candidiasis. The applied therapy was inefficacious. Subsequent examinations pointed to a combined humoral and cellular immunopathy. At the age of 7 years the patient was readmitted with abdominal complaints. Diagnostic laparotomy revealed a tubercu... | 367,051 | [
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Introduction to mechanisms of association of indigenous microbes. | Indigenous microorganisms of numerous types associate with epithelial surfaces in the gastrointestinal tracts of mammals and birds. Some of the microbial types, e.g., Lactobacillus sp. in the stomachs of laboratory rodents, adhere to a surface without altering it ultrastructurely. In such cases, the adherence is mediat... | 367,138 | [
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Deposition of circulating antigen--antibody complexes in the gastrointestinal tract of rabbits with chronic serum sickness. | The possible role of circulating immune complexes (IC) in the production gastrointestinal lesions was studied in rabbits with chronic serum sickness (CSS) induced by multiple daily injections of bovine serum albumin (BSA). All rabbits generating a marked antibody response developed IC glomerulonephritis. In approximate... | 367,154 | [
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Histological enamel indicator of childhood stress in prehistoric skeletal samples. | Although previous paleopathological studies have used disturbances in enamel formation as indicators of childhood stress, the full potential of this technique has not been realized. This paper presents a test case which demonstrates that the frequency of disturbed enamel formation (i.e., Wilson bands) is associated wit... | 367,176 | [
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Use of ambulatory health services by the near poor. | Individuals in the gray area between Medicaid eligibility and sufficient income to meet the costs of health care, the near poor, utilize health services less than other groups. As part of a study of health care behavior in an inner-city area based on a household survey of three distinct populations (HMO) members, publi... | 367,186 | [
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Impact of alcohol misuse on family life. | The shame that surrounds problem drinking contributes to delay or failure of remedy; the family tries to hide the drinking of its member from neighbors and even from the doctors. All parties to the illness choose to ignore the alcoholism and its implication for the patient. | 367,203 | [
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The minor alcoholics and their treatment. | The codiscoverer of disulfiram's usefulness for alcoholics reports on the development of Denmark's present system of alcoholism treatment and the treatment facilities. | 367,206 | [
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Treatment of herpes simplex keratitis with idoxuridine and vidarabine: a double-blind study. | A double controlled clinical study comparing idoxuridine (IDU) and vidarabine (ara-A) in the treatment of uncomplicated herpes simplex keratitis was carried out with 10 patients. No statistically significant differences occurred in the healing time between IDU (6.8 days) and ara-A (8.0 days). Two moderately adverse rea... | 367,239 | [
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The excretion of urinary N-acetyl-beta-glucosaminidase and beta-glucuronidase as a sign of impending rejection of kidney transplants. | An evaluation was made of the assay of two urinary lysosomal enzymes, N-acetyl-beta-glucosaminidase and beta-glucuronidase, in the diagnosis of impending rejection of renal transplant. The output of enzymes was measured in 34 cadaver transplant recipients, 17 of whom underwent rejection episodes. The enzyme output duri... | 367,256 | [
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[Delayed type hypersensitivity reactions to "Candida albicans" in mice (author's transl)]. | Mice injected intravenously (IV) or subcutaneously (SC) with living Candida albicans developed subsequently delayed-type hypersensitivity (DTH) which was measured in vivo by the footpad test after injection of 10(6) heat killed C. albicans (HKC.a.). Compared to systemic injections, SC immunizations with living C.a. gav... | 367,260 | [
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Smouldering epidemic of Yersinia pseudotuberculosis in barn rats. | Yersinia pseudotuberculosis was isolated from 8 (8 Rattus norvegicus) of 270 (259 R. norvegicus and 11 R. rattus) rats examined. Seasonal variation was not found in the incidence of isolations. The isolation occurred almost equally in both young and old rats. The isolated strains were determined as serovar IB in one ra... | 367,272 | [
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Defective neutrophil migration in granuloma annulare, necrobiosis lipoidica, and sarcoidosis. | The neutrophil mobility in patients with granuloma annulare, necrobiosis lipoidica, and sarcoidosis was tested using both in vivo and in vitro techniques. Use of a skin window chamber for measurement of chemotaxis in vivo demonstrated defective neutrophil migration in each group. This contrasted with the finding that, ... | 367,286 | [
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0.0862187,... |
[The investigation of lead levels in vertebra and rib samples (author's transl)]. | The dithizone extraction method has been applied in the determination of lead content in human bones. The lead in 21 samples of fresh vertebrae and ribs from autopsies is compared with the lead content of historical bones of 17 skeletons from 600--800 A.D. The preparation and the direct mineralization of the bones are ... | 367,315 | [
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Napoleon Bonaparte's exposure to arsenic during 1816. | Analysis of hair from Napoleon showed that he was exposed to considerable amounts of arsenic during 1816. The distribution pattern of the arsenic in the hair is similar to that found after the daily ingestion of excessive amounts of arsenic. | 367,316 | [
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Primary selective deficiency of immunoglobulin M. | Selective deficiency of IgM as a primary disorder is seldom encountered1--3, and the syndrome remains ill-defined4. It is generally accepted that for a diagnosis to be made, the serum IgM level should be consistently below 2 SD of normal, no other immunodeficiencies are present, and it is not secondary to other disease... | 367,347 | [
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Thrombin: structural features related to specificity. | A comparison of the primary structure of human thrombin with the structures of chymotrypsin, trypsin, elastase and factor Xabeta reveals several structural features which may be involved in the specificity of thrombin toward macromolecular substrates. Among the major structural differences noted in such a comparison ar... | 367,359 | [
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Functional mutants of yeast alcohol dehydrogenase affecting kinetics, cellular redox balance, and electrophoretic mobility. | Repeated selection of petite (respiratorily incompetent) Saccharomyces cerevisiae on medium containing allyl alcohol, both on plates and in the turbidostat, results in mutants with a remarkably similar response. Most of the mutations affect the constitutive alcohol dehydrogenase, resulting in enzymes with a cathodal sh... | 367,361 | [
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Purification of the hexokinases by affinity chromatography on sepharose-N-aminoacylglucosamine derivates. Design of affinity matrices from free solution kinetics. | The purification is described of rat hepatic hexokinase type III and kidney hexokinase type I on a large scale by using a combination of conventional and affinity techniques similar to those previously used for the purification of rat hepatic glucokinase [Holroyde, Allen, Storer, Warsy, Chesher, Trayer, Cornish-Bowden ... | 367,363 | [
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Purification of 3-phosphoglycerate kinase from diverse sources by affinity elution chromatography. | 1. Affinity elution chromatography was used to purify phosphoglycerate kinase from a variety of sources. The choice of buffer pH for the chromatography was made according to the relative electrophoretic mobility of the enzyme from the species concerned. 2. Outlines of the methods used to isolate the enzyme from over 20... | 367,367 | [
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Horizontal splitting in patellar articular cartilage. | Horizontal splits at the interface between the uncalcified and the calcified layers of the articular cartilage have been found in 31 of 50 transverse slabs of left patellae from a random series of 50 necropsy subjects aged 18 to 96 years, Evidence is presented that the splits are not due to autolysis nor to technical a... | 367,378 | [
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Responses of human and baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: their relevance to cerebral arterial spasm in man. | 1 Isolated strips of human or baboon basilar, middle cerebral, vertebral or common carotid arteries were set up in an isolated organ bath or in a superfusion cascade system. 2 These arteries relaxed to prostacyclin but contracted to prostaglandin endoperoxide (PGH2). 3 Human and baboon isolated arteries also generated ... | 367,413 | [
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Characteristics of proline transport in normal and starved cells of Candida albicans. | 1. There was no apparent correlation between the rate of respiration and rate of accumulation of proline in Candida albicans cells. 2. In contrast to normal cells, the respiration in the starved cells became completely cyanide insensitive. The starvation of cells in the presence of cycloheximide prevented the cells fro... | 367,434 | [
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Value of examining buffy coats for intragranulocytic micro-organisms in patients with fever. | To determine the significance of the presence of intragranulocytic micro-organisms in the blood buffy coat in patients with suspected infection, buffy coat examination and blood cultures were simultaneously performed in 455 consecutive patients with fever. There was no general correlation between the finding of intragr... | 367,502 | [
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Cardiac transplantation in 150 patients at Stanford University. | A total of 150 patients underwent cardiac transplantation at Stanford between January 1968 and August 1978. Sixty-two patients were alive at the end of this period, when the expected one-year survival rate was 70%, with an attrition rate of roughly 5% thereafter. Changes in postoperative managment resulting from contin... | 367,504 | [
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Randomised controlled trial of vancomycin for pseudomembranous colitis and postoperative diarrhoea. | The efficacy of vancomycin in pseudomembranous colitis was assessed in a prospective randomised controlled trial. Forty-four patients with postoperative diarrhoea were allocated to five days' treatment with either 125 mg vancomycin six-hourly or a placebo. Sixteen patients had high titres of the neutralised faecal toxi... | 367,509 | [
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Treponema pallidum immune adherence test for serodiagnosis of syphilis. 2: Comparison with glass plate, TPHA, and FTA-ABS tests. | Using sera from 340 patients with syphilis the Treponema pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum haemagglutination (TPHA), and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of the TPIA test agreed with those of the glass plate, TPHA, and FTA-ABS tests... | 367,524 | [
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Liposarcomas of the head and neck: a review of the literature and addition of four cases. | Liposarcomas of the head and neck are rare. There have been 25 previously reported patients in the literature. Four patients with head and neck liposarcomas, recently treated by the Head and Neck Surgery Service, Walter Reed Army Medical Center, are presented. Less than half of reported patients were noted to be living... | 367,565 | [
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Renal metastases from well differentiated follicular thyroid carcinoma: a case report with light and electron microscopic findings. | The second case of metastatic follicular carcinoma of the thyroid presenting during life as bilateral renal masses is described. Metastases appeared 18 years after resection of the primary and on clinical evaluation were confined to the kidneys. Although most malignant tumors which present clinically in the kidney are... | 367,568 | [
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Low dose chemotherapy of metastatic breast cancer with cyclophosphamide, adriamycin, methotrexate, 5-fluorouracil (CAMF) versus sequential cyclophosphamide, methotrexate, 5-fluorouracil (CMF) and adriamycin. | Seventy-eight advanced breast cancer patients with hormone-resistant disease or visceral metastases were randomized to receive either of two low dose regimens consisting of cyclophosphamide (C), methotrexate (M), 5-fluorouracil (F), and Adriamycin (A) as their initial chemotherapy. One group was treated with CAMF, and ... | 367,574 | [
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[Goodpasture's syndrome]. | 1. The paper summarizes the clinical course, histopathological examinations and immunohistological examinations of 4 personal cases [2 males aged 20 and 26 years, 2 females aged 65 and 18 years] of Goodpasture's pulmorenal syndrome. 2. The characteristic histopathological findings included pulmonary haemorrhage with a ... | 367,611 | [
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The hemodynamic effects of prostaglandins in the rat. Evidence for important species variation in renovascular responses. | The hemodynamic effects of prostaglandins E2, F2alpha, D2, and I2, and of indomethacin and arachidonic acid were studied in Sprague-Dawley rats, by means of the radioactive microsphere technique. In contrast to effects in other species, PGE2, PGD2, and arachidonic acid were renal vasoconstrictors in the rat, although P... | 367,631 | [
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The mechanism of imipramine in enuresis nocturna. | 1. To evaluate the mechanism of action of imipramine in enuresis nocturna, we compared the effects of imipramine with those of scopolamine butylbromide in fourteen children suffering from this condition. A double-blind, cross-over design was used. 2. Imipramine, 10--20 mg, was superior to scopolamine butylbromide (10--... | 367,655 | [
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Toxicologic assessments in acute heroin fatalities. | The recent improvements in analytic methods enable routine morphine detection in blood in microgram or nanogram quantities. It is now possible to assess acute death from heroin use by toxicologic analyses. A review of available data indicates a rapid distribution of morphine even in sudden fatalities, to the various or... | 367,692 | [
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0.06761298,
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Fenbufen compared with indomethacin in osteoarthrosis. | A double-blind, crossover clinical trial was carried out with a new propionic acid derivative, fenbufen, versus indomethacin and placebo in 20 patients with osteoarthrosis. Active drug dosages of 75 mg indomethacin daily and 600 mg fenbufen daily were used. Fenbufen scored significantly better than placebo with respect... | 367,713 | [
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Criteria for selective positive end-expiratory pressure and independent synchronized ventilation of each lung. | Respiratory failure of different origins often requires therapy with mechanical ventilation and positive end-expiratory pressure (PEEP). These supports are occasionally inadequate if the damage to one lung is significantly more pronounced than that to the other lung. Technical means exist to ventilate each lung indepen... | 367,723 | [
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[Problems of bacteriologic diagnosis and aimed antibiotic therapy in pyogenic maxillofacial infections]. | Bacteriologic analysis of pathogens from pyogenic infections of the jaw in 71 patients revealed that bacteria normally found in the buccal cavity predominated in 86% of the specimens. Considering the fact that no pathogens could be identified in 7% of the specimens, this then means that pathogens were only found in 7% ... | 367,753 | [
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... |
Excretion of valproic acid into semen of rabbits and man. | Dipropylacetic acid (VPA, valproic acid) has been quantified in plasma and semen from rabbits and man using a new gas-liquid chromatographic assay. The drug assay is rapid, sensitive and free from interference by VPA metabolites. The beta phase half-life of VPA in rabbits after an i.v. dose (50 mg/kg) was 56 +/- 6 min.... | 367,760 | [
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Sorption of pollutants by plant detritus: a review. | Detritus particles derived from the decomposition of vascular plants appear to have a high sorptive capability for a wide range of pollutants. Evidence is presented and reviewed which shows detrital concentration of heavy metals, radionuclides, and organochlorine insecticides. A study of a roadside marsh indicates that... | 367,765 | [
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Transport and transportation pathways of hazardous chemicals from solid waste disposal. | To evaluate the impact of hazardous chemicals in solid wastes on man and other organisms, it is necessary to have information about amounts of chemical present, extent of exposure, and chemical toxicity. This paper addresses the question of organism exposure by considering the major physical and biological transport pa... | 367,772 | [
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Utility of specific locus systems in higher plants to monitor for mutagens. | Plants possess biological and operational attributes that have encouraged geneticists to use them extensively in the development of fundamental genetic concepts. Attributes such as regenerative plasticity, high fecundity, cultural adaptability, range of ploidy, economics of culture and maintenance of specific populatio... | 367,776 | [
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0.3801145,
0.0394019,
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0.1029786,
0.01329579,
0.2109601,
-0.3230418,
-0.1046997,
-0.3986342,
-0.02826571,
0.03921516,
-0.03028176,
0.2440712,
0.3344828,
-0.255932,
-0.2... |
Histological changes in thyroid of rat under the acute exposure of O-chloro-benzylidine malononitrile. | This communication describes histological changes in the thyroid gland of rats under the acute stress of O-chlorobenzylidene malononitrile (CS) 10 mg/kg and 20 mg/kg). It has been observed that CS, when injected, causes histological changes in the thyroid of varying degrees, depending on the dose used. | 367,807 | [
-0.2409289,
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0.334463,
0.1407847,
0.1103161,
0.1271086,
0.1252385,
-0... |
Synthesis of vitellogenin, an attractive model for investigating hormone-induced gene activation. | The estrogen-induced synthesis of vitellogenin in the frog Xenopus and the chicken is an attractive system for investigating the molecular events leading to the activation of a specific gene. In this review article the events occurring at the level of the protein and mRNA in the cytoplasm are discussed. The available d... | 367,848 | [
-0.03539578,
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0.1851866,
0.01535704,
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0.5176044,
0.1729387,
-0.0984235... |
Governance: trustees are closing the gap between hospitals and consumers. | Many trustees today believe that they are in the best position to cement the relationship between their hospital and its service population. | 367,918 | [
-0.0773932,
0.1894326,
0.05668133,
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0.1677125,
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0.1847674,
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Labor relations: union activity increases among professionals. | Hospital labor relations managers need a higher level of skills today to deal with increasingly complex labor-management negotiations. | 367,921 | [
0.1035638,
0.08796629,
0.06198252,
0.1091018,
0.1381022,
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0.06085567,
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0.2665374,
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... |
Medical staff: physicians seek new responses to mounting pressures. | In responding to pressures to contain cost and improve the quality of care, medical staff are becoming increasingly involved in policymaking and managerial decisions. | 367,924 | [
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0.03282059,
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0.2737312,
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0.03275737,
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0.08252146,
0.01869841,
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0... |
Disappearance of oxytocin-induced uterine tiredness by treatment with fructose-1,6-diphosphate. Experimental evidence. | Fructose-1,6-diphosphate (FDP) is able to abolish oxytocin induced spastic inertia in rat uterus. The clinical use of FDP is suggested by observation carried out on 30 deliveries with oxytocin induction. The FDP-treated patients (5 g of FDP in 50 ml of water by intravenous infusion) showed a statistically significant d... | 367,980 | [
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0.1877865,
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0.2627383,
0.2910574,
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0.1024405,
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0.1430502,
0.2010118,
-0.07743371,
... |
Enzymatic studies on the mechanism of action of cefoxitin. Correlation between the affinities of cefoxitin to penicillin-binding proteins and its rates of inhibition of the respective penicillin-sensitive reactions in E. coli. | The affinities of cefoxitin, a cephamycin antibiotic, to penicillin-binding proteins of Escherichia coli were reexamined using a recently developed method for separating penicillin-binding proteins. The inhibitions by this antibiotic of four measurable penicillin-sensitive enzymatic reactions, the reactions of D-alanin... | 368,000 | [
0.09882957,
-0.1050109,
-0.1339454,
0.07227618,
0.1353222,
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0.0508316,
0.05718046,
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0.1741035,
0.1277409,
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0.1607498,
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-0.0318249,
-0.1459838,
0.2624956,
0.1485122,
-0.1912099,
0.004990088,
... |
The bacterial outer-membrane permeability of beta-lactam antibiotics. | Two penicillins and 5 cephalosporins were evaluated for their ability to pass through the outer-membranes of Proteus morganii, Citrobacter freundii and Escherichia coli. Cefazolin, ceftezole and cephaloridine showed high permeability through the outer-membranes of these Gram-negative bacteria. Benzylpenicillin and ceph... | 368,002 | [
0.216106,
0.1707521,
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0.1235273,
0.02169054,
0.002965518,
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0.1015955,
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0.02400694,
0.2626743,
0.2394935,
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0.4810731,
-0.3205557,
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0.06410064,
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-0.165845,
0.4738171,
-0.112668,
0.1695942,
-0.1... |
Relationship of glycolytic intermediates, glycolytic enzymes, and ammonia to glycogen metabolism during sporulation in the yeast Saccharomyces cerevisiae. | To identify the factors which control glycogen synthesis in Saccharomyces cerevisiae, we have studied the regulation of glycogen metabolism during sporulation, since in vivo glycogen has been reported to undergo significant changes in concentration during this process. We examined the concentration of a number of key g... | 368,017 | [
-0.3504766,
-0.08514129,
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-0.03957336,
-0.1003685,
-0.3182496,
0.1313663,
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-0.001004167,
0.05067544,
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-0.01932008,
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-0.01695112,
0.4908023,
0.137833,
-0.10452... |
ColE1 hybrid plasmids for Escherichia coli genes of glycolysis and the hexose monophosphate shunt. | The Clarke-Carbon clone bank carrying ColE1-Escherichia coli DNA has been screened by conjugation for complementation of glycolysis and hexose monophosphate shunt mutations. Plasmids were identified for phosphofructokinase (pfkA), triose phosphate isomerase (tpi), phosphoglucose isomerase (pgi), glucose-6-phosphate deh... | 368,027 | [
-0.2402761,
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0.0285714,
0.02730172,
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0.06439405,
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0.3749543,
0.394348,
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0.6149229,
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-0.298053,
0.2440932,
0.04683674,
-0.04795446,
0.2878597,
0.3797817,
-0.3333806,
... |
Two-component nature of bacteriophage T4 receptor activity in Escherichia coli K-12. | Escherichia coli bacteriophage T4 uses the lipopolysaccharide of the outer cell envelope membrane as a receptor. Lipopolysaccharide from E. coli K-12 required a major outer membrane protein, polypeptide Ib, for phage inactivation. | 368,036 | [
-0.1499856,
0.247658,
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0.01726376,
0.1653782,
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0.361758,
0.3064459,
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... |
Construction and properties of a cell-free system for bacteriophage T4 late RNA synthesis. | A cell-free system for synthesizing bacteriophage T4 late RNA is described. The system, which is based on the "cellophane disc" technique introduced by Schaller and co-workers (Schaller, H., Otto, B., Nüsslein, V., Huf, J., Hermann, R., and Bonnhoeffer, F. (1972) J. Mol. Biol. 63, 183-200), provides favorable condition... | 368,054 | [
0.12716,
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0.2121041,
0.1851037,
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0.05868904,
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0.1205741,
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0.1711871,
0.811266,
-0.2752455,
-0.4355521,
0.1766... |
Cloning of genes for bacterial glycosyltransferases. I. Selection of hybrid plasmids carrying genes for two glucosyltransferases. | A method of identifying plasmids containing genes responsible for synthesis of nucleotide sugar:lipopolysaccharide glycosyltransferases is described. Hybrid ColE1 plasmids containing random fragments of the chromosome of Escherichia coli K12 were introduced into an indicator strain of Salmonella typhimurium which lacks... | 368,061 | [
0.2045009,
-0.08154582,
-0.4650156,
-0.1685666,
-0.001831361,
-0.2609513,
-0.2139102,
0.2222699,
0.2389813,
-0.0002936867,
0.3003496,
-0.2578985,
-0.10157,
0.1323383,
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0.142337,
-0.1921226,
0.02414222,
0.2065743,
0.07425572,
0.2971256,
0.01179537,
-0.2067062,
... |
The structure of cytochrome b562 from Escherichia coli at 2.5 A resolution. | The structure of cytochrome b562 from Escherichia coli has been determined at 2.5 A resolution by x-ray diffraction methods. Protein phases were computed by the single isomorphous replacement method with anomalous scattering measurements from the native and uranyl acetate-substituted crystals. The electron density was ... | 368,073 | [
-0.2478338,
0.1767778,
-0.3598155,
0.2035142,
0.06926487,
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0.02843532,
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0.03428165,
0.1732183,
0.04547526,
-0.07178909,
-0.03851173,
0.1711165,
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0.2989621,
-0.006791241,
0.04898685,
-0.1856996,
-0.1042865,
0.2642961,
0.2413713,
-0.07265589... |
Effect of Simplex liquid methyl methacrylate monomer on cells. | The effect of methyl methacrylate monomer used for polymerization of surgical bone cement on phagocytosis, blood cells, tissue cells in culture, and bacteria was investigated. A concentration of 0.5% monomer reduced the ability of macrophages in vitro to phagocytize cultures of Staphylococcus epidermidis effectively. I... | 368,077 | [
-0.04184297,
0.07355282,
-0.179803,
0.001747286,
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0.1224745,
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0.1700471,
0.1729046,
-0.2586385,
0.09044202,
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0.03592211,
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0.05335408,
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0.6901488,
0.3215613,
0.1489354,
0.1960791,
... |
A scanning electron microscope comparison of three methods of bonding resin to enamel rod ends and longitudinally cut enamel. | Taglike projections of resin into the etched enamel surface and longitudinally cut enamel were studied under the SEM. Three methods of bonding, including the use of a bonding agent and a primer, were compared. Freshly extracted teeth were pumiced, rinsed, and dried. The enamel surface was etched for a minute with phosp... | 368,101 | [
0.1052889,
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0.2936391,
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0.1599428,
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0.4962532,
0.4307207,
0.1767132,
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0.09527707,
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0.1416271,
0.1023326,
-0.1816247,
0.2218677,
0.2210121,
0.00600394,
-0.2... |
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