title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Methysergide induces selective potentiation in cholinergic contractions of the guinea-pig vas deferens by facilitating acetylcholine release. | Methysergide (3 x 10(-6) M) enhanced the contractile responses of the isolated stripped vas deferens of guinea-pig to acetylchline(ACh) and arecoline, but not those to noradrenaline, tyramine and bradykinin. Methysergide (3 x 10(-5) M) suppressed the contraction elicited by noradrenaline or histamine. The methysergide-... | 43,366 | [
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Colorimetric determination of 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol with 2,4,6-trinitrobenzenesulfonic acid in the presence of chloramphenicol. | A colorimetric method based on the interaction between the chloramphenicol degradation product 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol and the 2,4,6-trinitrobenzenesulfonic acid reagent was developed. Analytical solutions were reacted with the reagent at pH 9.1 for 20 min at room temperature, and the resulting color... | 43,388 | [
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[The development in the treatment of supracondylar femur fractures (author's transl)]. | Author compared the material of supracondylar femur fractures of the National Institute of Traumatology during a period of 5 years starting from 1962 until 1966 with that of a period of 6 years starting in 1972 until 1977. From among their 108 cases osteosynthesis was performed in 38 cases. He gives account of methods ... | 43,426 | [
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[Remarks to the operative treatment of arthritis of the knee (author's transl)]. | Author deals with operative treatment in secondary arthritis following severe trauma of the knee. Review of operative techniques and their problemes are given. The results of and total prosthetic replacement are compared with those of arthrodesis. It is concluded that in order to obtain the best result in prevention of... | 43,431 | [
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[Bolted medullary nailing (author's transl)]. | Authors described the development of bolted medullary nailing and presents indications and technique. Points out the advantages of the procedure, but the difficulties in aiming, a basic part of the technique is also mentioned. With selfconstructed guide and other modifications the applicability of bolted medullary nail... | 43,433 | [
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[Operative elimination of shoulder contracture maintained by subaxillary scarring (author's transl)]. | In order to avoid irreversible changes the solving of shoulder contracture caused by subauxillary scarring is an urgent task. His method is the Z-plastic with many variables the choice and application of which are dependent from the extension and site of the subauxillary scar. | 43,434 | [
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[The treatment of burns--an autonomous discipline (author's transl)]. | In Europe Hungary was among the initiators to establish specialised surgical departments for the treatment of burnt patients. This new element in the structure of the hospital resulted in specialisation of surgeons for skin replacement and scar surgery. Thus the surgeon treating burnt patients is becoming the "surgeon ... | 43,436 | [
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Phospholipid metabolism in Neisseria gonorrhoeae: phospholipid hydrolysis in nongrowing cells. | Hydrolysis of cell envelope phospholipids was demonstrated in cells of both autolytic and nonautolytic strains of Neisseria gonorrhoeae that were labeled during growth in the presence of [3H] acetate. The label incorporated into the cellular phospholipids was located exclusively in the fatty acid acyl side chains. Labe... | 43,450 | [
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Superhelical DNA in Streptococcus sanguis: role in recombination in vivo. | Competent Streptococcus sanguis treated with non-lethal doses of coumermycin A1 immediately before or after uptake of radioactive transforming DNA were reduced in their capacity to yield transformants. This treatment did not alter bacterial ability to bind DNA in DNase I-resistant form, nor did it prevent the single-st... | 43,456 | [
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[Effect of cultivation conditions on growth of Candida lipolytica yeasts and alpha-ketoacid biosynthesis in the presence of thiamine deficiency]. | The effect of pH and aeration on the growth of Candida lipolytica and the biosynthesis of alpha-keto acids on acetate and glucose was studied in batch cultures at thiamine deficiency. If the initial thamine concentration was the same, then, irrespective of the carbon source, the yeast biomass in a medium saturated with... | 43,461 | [
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[Fluorescent probe study of staphylococcal cell wall charges]. | The effect of pH and MgCl2 concentration on the fluorescence of 1-anilinonaphthalene-8-sulfonate (ANS), an anion probe, was studied in suspensions of Staphylococcus aureus. The maximum of ANS fluorescence shifted towards the short wavelength region of the spectrum and its intensity increased when the cells were incubat... | 43,463 | [
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[Physiologo-biochemical features of the growth and development of Propionibacterium shermanii in egg albumin]. | Propionibacterium shermanii was shown to be able of growing in such an unusual substrate as egg albumen. Incubation of the bacterium in egg albumen results in complete utilization of free carbohydrates in this substrate and accumulation in it of such bacterial metabolites as vitamins B2 and B12, free amino acids, bacte... | 43,462 | [
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Control of acetyl-CoA carboxylase by covalent modification. | In this review, various experiments which establish the occurrence of covalent modification mechanisms, both in vivo and in vitro, in the control of acetyl-CoA carboxylase have been presented. It is interesting to note that phosphorylation of the carboxylase results in disaggregation of the active species. These studie... | 43,470 | [
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Increase by alpha-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum. | The release of acetylcholine evoked by field stimulation of the guinea-pig ileum (3 Hz) is increased by yohimbine and tolazoline but not affected by phentolamine. It is proposed that yohimbine and tolazoline by blocking alpha-adrenoceptors of the cholinergic nerves abolish the inhibition caused by endogenous noradrenal... | 43,477 | [
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The influence of preganglionic nerves on the superior cervical ganglion of the rat. | Sympathetic neurones grown in tissue culture with non-neuronal cells become cholinergic. Such a change from an adrenergic to cholinergic character does not occur in vivo and it has been suggested that this may be due to the determination of the adrenergic character by electrical activity. Electrical activity in the sup... | 43,489 | [
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[X-ray diffraction analysis of disintegration of polyglycolic acid suture material both in vivo and in model media]. | Examined were the structural variations of polyglycolic acid surgical suture material by X-ray diffraction methods subsequent to sejour in vivo and in several model mediums. After a long stay in vivo, water and buffer at pH 2 the following structural variations in the polymer were observed: diminution of macroperiod, a... | 43,508 | [
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Geochemistry and health in the United Kingdom. | Before the 1960s, comparisons between the distribution of trace elements in the environment and health in the United Kingdom were primarily confined to ad hoc studies in areas associated with particular agricultural disorders or with unusual human mortality or morbidity records. More recently, increasing interest in th... | 43,529 | [
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Geochemistry and cardiovascular diseases. | Deficiencies or excesses in the content or availability of trace elements in rocks and soils, or in water flowing through them, is hypothesized as a possible cause of certain chronic diseases, including cardiovascular diseases. Geographic distribution of cardiovascular diseases is often associated with geochemical diff... | 43,533 | [
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Trace elements and health: an overview. | Trace element deficiencies, toxicities and imbalances in man are more difficult to relate to geochemical factors than they are in farm animals. The reasons for this are discussed and examples of such differences between man and grazing animals presented. The most convincing evidence of a geochemical causal link with hu... | 43,537 | [
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Trace elements in animals. | Trace element deficiency and toxicity in animals induces a wide variety of clinical effects although few are sufficiently specific to permit diagnosis without supporting investigation of changes in tissue trace element content or of the activity of metabolic processes influenced by trace element supply. Study of such t... | 43,538 | [
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Regional geochemical mapping. | One of the prime requirements for effective study of environmental geochemistry in relation to health is the production of multi-element atlases showing the distribution of the elements on the regional scale. The choice of method for compiling such atlases can vary according to a number of geological, environmental and... | 43,540 | [
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Verdohemoglobin as a substrate for proteases is applicable to assays over a wide pH range. | Verdohemoglobin, a heme-modified derivative readily obtained by ascorbic acid-coupled oxidation of oxyhemoglobin, was found to be a suitable substrate for protease with which assay can be carried out at all pH values. The advantage of verdohemoglobin over such popular substrates as alkali-and-urea-denatured hemoglobin ... | 43,544 | [
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Impaired performance and sedation after a single dose of lorazepam. | In a double-blind cross-over study using normal student volunteers, the effects of 1 and 2.5 mg lorazepam on self-rated mood and bodily symptoms, as well as performance in a number of tests were assessed. Both doses significantly increased self ratings of physical and mental sedation, the effects being more marked 4 h ... | 43,554 | [
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Candida lipolytica isolated from Guanabara Bay and its ability to grow in marine and estuarine conditions. | Although the petroleum degrading ability of Candida lipolytica is well known, its ability to grow in seawater is questionable. Sixteen strains of C. lipolytica were isolated from marine sites in Rio de Janeiro. Some variations from the standard description were noted including strains intermediate between the varieties... | 43,560 | [
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[Storage behavior of Collins' solution under various conditions]. | It is reported on examinations of the precipitation reactions in the Collins solution. The solution which is produced in three and two compartments, respectively, has been given together and stored under three different conditions. During a period of 48 hours the electrolytes sodium and potassium and the pH-value were ... | 43,634 | [
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[Treatment of a case of chronic obsessive troubles through combined behavioral therapy (author's transl)]. | Behavior therapy of a young man, suffering from grave obsessive and compulsive troubles is the first example of combined therapy, with individual therapy, family therapy as group therapy. Two steps are find in the cure. There are benefits--trust and hope--due to psychiatric hospitalization and generous and constant aff... | 43,661 | [
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[Psychological theories in the context of an interdisciplinary gerontology (author's transl)]. | The integration of the different disciplines of gerontology can be promoted by pointing to the analogies in biological, medical, psychological, and sociological constructs and theories of aging. Max Bürger's construct of "biomorphosis", the functional age approach in physiology, and the principle of homeostasis can con... | 43,671 | [
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[Medical data from a gerontological field-study and its value with regard to the conception of a psychogeriatric service (author's transl)]. | 1114 people were investigated by a sociological interview. A representative subgroup got a medical check-up mostly by psychiatrists, a few of them by the family doctors. It revealed a refusal-group of 28% out of 625 persons. Our medical data did not confirm the rate of morbidity from 10 to 20% of the elderly. Whereas t... | 43,673 | [
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0.3098835,
0.1411366,
0.654056,
0.4579659,
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... |
Structural studies of a branchiopod crustacean (Lepidurus bilobatus) extracellular hemoglobin. Evidence for oxygen-binding domains. | The extracellular hemoglobin of the notostracan branchiopod Lepidurus bilobatus has an apparent molecular weight of 680,000 and may exist in a dissociation-association equilibrium dependent on pH and ligand state. The pigment contains one heme per 18,000 g protein. However, attempts to dissociate the hemoglobin by hars... | 43,742 | [
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Conformational changes in human serum albumin around the neutral pH from circular dichroic measurements. | The molar ellipticity of the warfarin-albumin complex at 310 nm increases with pH from 6 to 9. This pH dependence runs parallel with that of the molar ellipticity of the albumin alone at 292 nm. The change in molar ellipicity with pH occurs in a smaller pH interval after addition of the physiological concentration of c... | 43,743 | [
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Tardive dyskinesia and dementia. | Seventeen schizophrenic patients with tardive dyskinesia (TD) and 33 schizophrenics without tardive dyskinesia were examined by psychological tests of intellectual function and EMI scans were performed. The group as a whole were found to be demented and 31 out of 45 had abnormalities on the scan. On a learning test the... | 43,754 | [
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The function of fimbriae in Myxococcus xanthus. II. The role of fimbriae in cell-cell interactions. | Anti-fimbriae antiserum specifically inhibited swarming but no gliding motility per se in Myxococcus xanthus. However, formation of motile aggregates on agar and clumps in liquid media correlated with the presence of fimbriae. Ethylenediaminetetraacetic acid which inhibited swarming also inhibited fimbriae formation. D... | 43,768 | [
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Virological surveillance for dengue haemorrhagic fever in Indonesia using the mosquito inoculation technique. | A dengue haemorrhagic fever surveillance system in Indonesia, based on virological and clinical observations, is described. The system uses the mosquito inoculation technique for virus isolation and is simple, economical, and well suited for endemic areas where support and facilities are limited. The data suggest that ... | 43,776 | [
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Irreducible dislocation of the metatarsophalangeal joints of the foot. | An unusual dislocation of the metatarsophalangeal joints of the third, fourth, and fifth toes with fractures of the neck of the second metatarsal bone occurred in a 23-year-old man. Hyperextension of the metatarsophalangeal joints is the mechanism of injury and is substantiated by the anatomic investigation. The metata... | 43,791 | [
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The effects of rubidium on mammary tumour growth in C57 blk/6J mice. | A high pH therapy for cancer arrived at theoretically was tested in mice by feeding them rubidium carbonate. Tumours were transplanted in the abdomen of mice and allowed to grow for 8 days. The mice were then divided into two groups. The control group was continued on conventional mouse chow. The test group, in additio... | 43,800 | [
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Brain regional levels of neurotransmitter amines as neurochemical correlates of sex-specific ontogenesis in the rat. | Brain regional levels of three neurotransmitter amines - serotonin (5-HT), norepinephrine (NE), dopamine (DA) - were measured in young rats prior to weaning to determine the extent to which modifications in levels of amines might reflect alterations in the sex steroid hormonal environment during the first postnatal wee... | 43,801 | [
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The pathochemistry of kernicterus. | The stoichiometry of bilirubin--albumin interaction has been analyzed and quantitated in several recent studies, confirming that albumin binding of bilirubin obeys the law of mass action [4, 5, 14, 16, 26, 36, 43, 46, 61, 65, 73, 92, 111]. These studies provide a basis for interpreting bilirubin transport, cell uptake ... | 43,803 | [
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0.3377395,
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-... |
The pharmacokinetics and biotransformation of the new benzodiazepine lormetazepam in humans. I. Absorption, distribution, elimination and metabolism of lormetazepam-5-14C. | The pharmacokinetics and metabolism of the new benzodiazepine lormetazepam were investigated in five male volunteers using the 14C-labelled drug (position 5). Lormetazepam was administered intravenously and orally, at a dose of 0.2 and 2 mg respectively, to each of the test subjects. Measurements of total radioactivity... | 43,806 | [
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Reversed-phase high-performance liquid chromatography of catecholamines and their congeners with simple acids as ion-pairing reagents. | We have investigated the value of various common acids as ion-pairing reagents for high-efficiency separations of catecholamines and their metabolites in reversed-phase high-performance liquid chromatography. The retention of norepinephrine, alpha-methylnorepinephrine, dopamine, alpha-methyldopamine, L-dopa, alpha-meth... | 43,866 | [
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Morphology of the antibody response to pneumococcal polysaccharide in mice. | In the course of an antibody immune response to pneumococcal polysaccharide - type III (S III) in mice a slight increase was observed in the proportion of plasma cells among the antibody-producing cells, reaching its peak at the time of decline of this reaction. On the basis of ultrastructural resemblance of these plas... | 43,878 | [
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0.08730964,
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Inhibitory alpha-adrenergic action of phenylephrine in guinea pig taenia caecum. | Phenylephrine, a selective alpha-adrenergic stimulant, caused a maximal relaxation of the taenia from guinea pig caecum in the concentration of 10(-6) g/ml. Phenylephrine in this concentration did not influence intracellular cyclic AMP and cyclic GMP levels. Although phenylephrine abolished the spontaneous spike discha... | 43,911 | [
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Antiallergic action of 6-ethyl-3-(1h-tetrazol-5-YL) chromone (AA-344) on immediate hypersensitivity reaction in rats. | A newly synthesized compound, 6-ethyl-3-(1H-tetrazol-5-yl)chromone (AA-344) given intravenously or orally inhibited considerably the 72-hr passive cutaneous anaphylaxis (72-hr PCA) induced by IgE in rats. The antiallergic action of AA-344 was neither due to the antihistamine or antiserotonin effect nor was it mediated ... | 43,912 | [
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Differential antagonism of antiavoidance, cataleptic and ptotic effects of neuroleptics by biperiden. | The interaction between neuroleptics and an anticholinergic, biperiden, in the antiavoidance, catalepsy and ptosis tests was investigated in mice for the purpose of predicting the extrapyramidal side-effects of neuroleptics. The cataleptic effect of most neuroleptics used was antagonized to some extent by biperiden, wh... | 43,913 | [
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0.02823271,... |
Unimportance of perivascular H+ AND K+ activities for the adjustment of pial arterial diameter during changes of arterial blood pressure in cats. | The role of perivascular H+ and K+ in the adjustment of pial arterial diameter during changes in arterial blood pressure was investigated in chloralose anesthetized cats. Blood pressure was reduced by i.v. mecamylamine or pentolinium and was increased by i.v. hypertensin. Pial arterioles and arteries with a control dia... | 43,961 | [
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0.2117689... |
The effects of sleep on neurons in isolated cerebral cortex. | Slabs of cat parietal cortex with some 2 mm of underlying white matter were surgically isolated from the rest of the nervous system, without interference with the superficial blood supply. Wire micro-recording electrodes were inserted into the isolated cortex; bone, muscle and skin wounds were repaired and the animal a... | 43,974 | [
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... |
[Controlled therapeutic study of spontaneous bucco-linguo-facial dyskinesias (author's transl)]. | A triple blind study has been conducted according to an original methodology to compare the effects of thioproperazine and tiapride on the spontaneous bucco-linguo-facial dyskinesias in the elderly. Side effects have been balanced to obtain a quantitative evaluation. Thioproperazine (3 x 3 mg/day) and tiapride (3 x 100... | 44,015 | [
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0.2322406,
0.02228985,
0.131709,
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The Rift Valley fever epizootic in Egypt 1977-78. 2. Ecological and entomological studies. | Epidemiological factors related to the introduction, spread and maintenance of Rift Valley fever (RVF) virus were studied during the 1977-78 epizootic in Egypt, Culex pipiens is the most ubiquitous and prevalent mosquito species in the Nile Valley and Delta. Isolation of RVF virus from unengorged C. pipiens, and demons... | 44,038 | [
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0.06319591,
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[Scanning microscopical observations on the foregut structures o mosquitoes and their role for the ingestion of microfilariae (author's transl)]. | Experiments on the transmission of Brugia malayi by various mosquitoes had shown that microfilariae ingested by some species were badly damaged when they reached the stomach, but were much less hurt in others. The structures of the foregut likely to cause these injuries, were investigated and documented by scanning mic... | 44,040 | [
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0.04327329,... |
[Mechanical force exercised on the elbow joint in olecranon fractures (author's transl)]. | Opinion is fairly unanimous on the need for surgical treatment of disclocated olecranon fractures. However, opinions differ regarding the mechanical backgrounds and practical application of the presently widely used tension wiring. The article attempts to clarify the picture of the forces involved in the humero-ulnar j... | 44,086 | [
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[Treatment of the relapsing dislocation of the patella (author's transl)]. | From 1970-1977, twenty-five patients were given surgical treatment for relapsing dislocation of the patella. The mean age of the patients was 22 years. The case material consisted of 18 female and 7 male patients. The average frequency rate of dislocation was three to fifteen times. (Reported from the BB-Accident Hospi... | 44,090 | [
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[Late surgical treatment of traumatic rupture of the oesophagus (author's transl)]. | The article reports on a 21-year old patient admitted on an in-patient basis after compressed air injury with a severe open craniocerebral lesion, and in whom the diagnosis of rupture of the oesophagus was made two weeks later only. Late surgical management by means of oesophagus suture and sealing of the diaphragm, wa... | 44,091 | [
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0.09795733,
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Immunization against Nippostrongylus brasiliensis in the rat. A study on the use of antigen extracted from adult parasites and the parameters which influence the level of protection. | It was found that protective immunity in excess of 90% reduction in worm burden could be stimulated against Nippostrongylus brasiliensis in rats by using an extract of adult Nippostrongylus worms. The level of protection achieved was influenced by several factors. Thus, the use of Bordetella pertussis as adjuvant signi... | 44,095 | [
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0.145... |
[Principles of analysis and the value of coronaro-ventriculography in coronary surgery]. | The examination which precedes any operation for revascularisation of the myocardium, coronaro-ventriculography, which has become a routine examination in specialised centres, should gain even further in reliability by anatomical examination of the vessels which it is used to study in vitro. A perfect knowledge of the ... | 44,135 | [
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... |
[Lupos erythematosus discovered during the course of a toxicodermia (author's transl)]. | The authors describes four cases of lupus erythematosus (LE) diagnosed during the course of a medication toxicodermia, which was always acute and variable in its severity (in one case it concerned a Lyell's syndrome). The lupus affection was made evident by the toxicodermia and lupic manifestations may regress spontane... | 44,163 | [
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Brain amines and peptides--their relevance to psychiatry. | The amine theory of affective disorder and the dopamine and endorphin theories of schizophrenia are controversial but heuristically valuable concepts that have emerged from the psychobiological revolution of the last decade. That revolution stemmed largely from the development of techniques for localizing and assaying ... | 44,187 | [
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0.1087859,
0.1804339,
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-0.3... |
Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. III. Developmental and biochemical aspects. | The electrophoretic variants of G6PD and 6PGD isolated from the Bogota Drosophila melanogaster population were characterized developmentally and biochemically. Changes in in vitro enzyme activity during development were comparable to those found for other dehydrogenases: an increase in the larval and adult stage and a ... | 44,188 | [
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0... |
[Influence of nicergoline on the cerebral blood flow and alpha-sympatholytical properties (author's transl)]. | The cerebral vasodilatory effect of 10-methoxy-1,6-dimethyl-ergoline-8 beta-methanol-(5-bromonicotinate) (nicergoline, Sermion) was examined by recording the cardiac output of the vertebral artery in the dog. As from a dosage of 25 micrograms/kg nicergoline increases permanently the cardiac output to a normal or nearly... | 44,198 | [
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0.5243891,
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0.07618269,
0.1481919,
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N-acylation of tyramines: purification and characterization of an arylamine N-acetyltransferase from rat brain and liver. | The N-acylation of tyramine isomers and other biogenic amines has been studied. The liver exhibits the highest activity towards tyramines, while the brain exhibits a low but significant activity. In the brain, tyramine N-acylation activity was heterogenously distributed. The arylamine N-acetyltransferase has been parti... | 44,212 | [
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... |
The action of tributyltin chloride on the uptake of proline and glutamine by intact cells of Escherichia coli. | Tributyltin chloride inhibits growth and uptake of glutamine and proline into intact cells of Escherichia coli. It causes efflux of the accumulated amino acids. A pH gradient generated in intact cells and everted membrane vesicles is dissipated by this compound. These effects do not require lipoic acid but are dependen... | 44,216 | [
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The action of tributyltin chloride on energy-dependent transhydrogenation of NADP+ by NADH in membranes of Escherichia coli. | Respiration- and ATP-dependent transhydrogenation of NADP+ by NADH in everted membrane vesicles from Escherichia coli is inhibited by nigericin but is relatively insensitive to valinomycin. The sensitivity to nigericin is enhanced 30-fold in the presence of valinomycin. It is concluded that both the transmembrane pH di... | 44,217 | [
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Detection of anticapsular antibodies to Bacteroides asaccharolyticus in serum from rabbits and humans by use of an enzyme-linked immunosorbent assay. | A sensitive serologic test, the enzyme-linked immunosorbent assay (ELISA), was used to detect serum IgG antibodies directed specifically to a capsular antigen of Bacteroides asaccharolyticus (previously known as Bacteroides melaninogenicus subspecies asaccharolyticus). Anticapsular IgG was measured in 30 specimens of r... | 44,309 | [
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... |
Mitochondrial ATPase of Zajdela hepatoma. VI. Effect of extramitochondrial ATP and pH on uncoupler-sensitivity of mitochondrial ATPase activity. | Coupled Zajdela hepatoma mitochondria were reported to exhibit uncoupler-insensitive ATPase activity. The results of this study show that under specific conditions the ATPase activity of Zajdela hepatoma mitochondria can be stimulated by uncouplers. These conditions include (a) the addition of ATP to the mitochondria b... | 44,347 | [
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0.09041364,
... |
Spontaneous generation of adriamycin semiquinone radicals at physiologic pH. | Adriamycin semiquinone radicals are spontaneously generated by adriamycin solutions at physiologic pH. Rate of radical formation and equilibrium-state radical yield increase with increasing pH from 7.4 to 8.85. The radicals are oxygen sensitive, but the mechanism of radical formation is oxygen independent and associate... | 44,371 | [
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0.2390173,
... |
Characterization of the two major species of slow reacting substance from rat basophilic leukemia cells as glutathionyl thioethers of eicosatetraenoic acids oxygenated at the 5 position. Evidence that peroxy groups are present and important for spasmogenic activity. | The most prominent slow reacting substance from rat basophilic leukemia cells (type I) was characterized by radiochemical, chemical and physical methods and shown to contain a C20 unsaturated fatty acid oxygenated at the 5 position and a sulfur containing side chain in thioether linkage at the 6 position. Its spasmogen... | 44,377 | [
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0.5775663,
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0.4757708,
0.004... |
Steps of thiosulfate oxidation by Thiobacillus thioparus and Th. coproliticus. | Chromatographic analysis was used for studying steps of thiosulfate oxidation by Thiobacillus thioparus and Th. coproliticus strains, isolated from Egyptian soil. Th. thioparus strains oxidized S2O3 to SO4 with the formation of polythionates, tetrathionate in particular, during the course of oxidation. However, strains... | 44,416 | [
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0... |
The effect of propranolol on the serotonin concentration in the portal plasma after vagal nerve stimulation in the cat. | Efferent cervical vagal nerve stimulation in the cat caused a marked increase of the portal plasma 5-HT concentration. This increase was more than two-fold within 15 min of stimulation. After cessation of stimulation portal plasma 5-HT returned to basal levels within 10 min. Treatment with the beta-adrenoceptor antagon... | 44,426 | [
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Cellular and environmental variables determining numbers of flagella in temperature-shocked Naegleria. | Naegleria gruberi amebae normally transform into biflagellated cells. When subjected to high temperatures during flagellate differentiation, populations develop an average of 4-5 flagella/flagellate. Attempts to maximize this phenomenon by altering cellular and environmental variables revealed that: (a) few Naegleria i... | 44,524 | [
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Seizure proneness and neurotransmitter uptake. | The ability of midbrain homogenates from two strains of mice to accumulate several putative neurotransmitters, or their precursor in the case of acetylcholine, has been examined. The high-affinity transport mechanisms toward glutamate, GABA, dopamine, and glycine were similar in both strains. The seizure-prone DBA21BG ... | 44,544 | [
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0.185816,
0.1636476,
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[Oxidative degradation of dibenzylsulfide]. | Dibenzylsulfid (DBS) as a model of the organic sulfur compounds in crude oil was converted by a mixed culture (containing Pseudomonas aeruginosa) into several water soluble organic substances. Whereas these compounds are detectable with DC- and IR-spectroscopic techniques, benzylmercaptoacetic acid (BMA) was the only i... | 44,589 | [
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0.04149342,
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A comparison of the non-specific acid phosphomonoesterase activity in the larva of Phocanema decipiens (Nematoda) with that of the muscle of its host the codfish (Gadus morhua). | The non-specific phosphomonoesterase (enzyme I) extracted from the larva of the codworm (Phocanema decipiens) is different from the enzyme (enzyme II) from the muscle of its host, the codfish (Gadus morhua). The pH optima were 4.0 and 4.5, and the KM values for p-nitrophenyl phosphate hydrolysis were 1.8 mM and 6.5 mM ... | 44,595 | [
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Activity of L-asparaginase in cells of Streptomyces karnatakensis. | Eight isolates capable of producing varying quantities of L-asparaginase and all identified as members of the genus Streptomyces were isolated from the soil and a suitable technique for the assay of intracellular L-asparaginase in actinomycetes was developed. The most potent L-asparaginase producer was identified as a ... | 44,600 | [
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[Experiences in the treatment of gas gangrene in accident surgery (author's transl)]. | It is reported on 105 patients with gas gangrene. 68 cases were caused by accident, 7 of them died. Only the gas chromatographic identification of toxin in blood was needed to assure diagnosis. In 46 cases of gas gangrene localized in the lower limbs, amputation was necessary in 12 cases; in 5 cases gangrene in the low... | 44,647 | [
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0.08352102,
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... |
Four-fold structural repeat in the acid proteases. | The observation that the acid proteases contain two structurally equivalent lobes related by a dyad through the active centre has been extended to show that in endothiapepsin each lobe contains two similar halves related by a further local dyad. In lobe 1 22 pairs of alpha-carbons are equivalent with a root mean square... | 44,681 | [
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[Epidemiologic features of pneumococcal meningitis in Africa. Clinical and serotypical aspects (author's transl)]. | Pneumococcal meningitis, because of their frequency and their severity, are regarded as an important problem of Public Health in Africa. In a great number of African countries, particularly Equatorial and Central Africa, the pneumococcus is the first agent of bacterial meningitis. The annual prevalence is estimated as ... | 44,737 | [
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0.3511107,
0.6974197,
0.5172763,
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[Pneumococcal serotyping. Multicentric inventory in hospital. Years 1977-1978 (author's transl)]. | For a period of 17 months, 670 pneumococci, mostly isolated in the Paris area, have been typed with contercurrent-immunoelectrophoresis ; 338 of them come from cases of pneumonia, bacteremia, meningitis and acute otitis media. An important regrouping of the most frequent serotypes among the 83 known serotypes makes pos... | 44,741 | [
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0.03752796,... |
[The influence of a beta-adrenolytic premedication on cardiovascular parameters and plasma free fatty acids during esophago-gastro-duodenoscopy (author's transl)]. | Three groups of patients with different premedications were examined for changes of blood pressure, heart rate, ECG and plasma free fatty acid levels during esophago-gastro-duodenoscopy: Group A was premedicated with Bunitrolol, group B was premedicated with Hyoscin-N-butyl-bromide and diazepam, group C was endoscopied... | 44,770 | [
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[An oral enteritis-vaccine composed of twelve heat inactivated Enterobacteriaceae. 1. Communication: Theoretical and epidemiological considerations (author's transl)]. | The infectious diseases of the human intestinal tract which are caused by bacteria must be distinguished into two groups on account of their different pathogenesis: the cyclic infections (typhoid fever, parathyphoid fever) and the local infections (cholera, dysentery, Salmonella enteritis, dyspepsia coli infections). T... | 44,783 | [
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0.3265935,
0.2004765,
0.1479586,
-0.08110... |
Identification of anaerobes on the Minitek System, compared to a conventional system. | The Minitek Miniaturized System (BBL) was compared to a conventional method (V.P.I.) for the indentification of anaerobes. Anaerobiosis was achieved by using the GasPak system (BBL) and a glove box. Gram staining, colonial morphology, gas-liquid chromatography and biochemical reactions as detailed in the Virginia Polyt... | 44,787 | [
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0.13... |
[Virological diagnosis of epidemic keratoconjunctivitis (author's transl)]. | Among 180 patients with proved adenovirus infection of the eye, 144 infections with adenovirus 8 (Ad 8) were found. 11 or 7 patients were infected with Ad 19 or Ad 4 respectively; further 18 cases were associated with 6 other serotypes. The main symptoms of epidemic keratoconjunctivitis (EKC) (pronounced inflammatory s... | 44,795 | [
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0.009392885,
... |
[Chronic pyelonephritis of older and old patients--a diagnostic problem in general medical practice (author's transl)]. | Chronic pyelonephritis is the most common renal disease of old age. The number of registered cases of this disease is below current diagnostic possibilities, since chronic urinary tract infection and chronic pyelonephritis still too rarely play a role in differential diagnostic considerations. Because of the insecure r... | 44,816 | [
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Restricted chimerism of peripheral blood cells after transplantation of allogeneic hemopoietic tissue in rabbits. | Allogeneic bone marrow or spleen cells were transplanted in rabbits treated with a single dose of 110 kmg/g of cyclophosphamide or four doses of 50 mg/kg. Chimerism of peripheral blood cells occurred in about 50% of the recipients, lasting from about the 14th day until 180 days after transplantation. The chimerism was ... | 44,834 | [
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... |
The role of ATP and lactic acid for mitochondrial function during myocardial ischemia. | Phosphorylation rates of canine heart mitochondria isolated after various periods of myocardial ischemia after cardioplegic arrest were correlated with the myocardial ATP-, lactate- and undissociated lactic acid content as well as with interstitial H+-concentration. The following correlation coefficients were found: AT... | 44,843 | [
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0.07403739,
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0.1130364,
0.3628131,
0.06021659,
0.01050368,... |
[Iatrogenic depression (author's transl)]. | A number of drugs are traditionally blamed for causing depression: in general medicine, the antihypertensives, the oral contraceptives and the appetite suppressants; in psychiatry, the neuroleptics. The identification of iatrogenic depression is difficult methodologically, for two reasons: 1. Detection of the depressio... | 44,864 | [
-0.1611525,
0.061573,
0.08012182,
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0.2325974,
0.002693733,
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0.2441787,
0.1568653,
0.2829022,
0.07041955,
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-... |
A redefinition of normal acid-base equilibrium in man: carbon dioxide tension as a key determinant of normal plasma bicarbonate concentration. | It has been shown recently that normal acid-base equilibrium in the dog is characterized by a strong positive correlation between plasma bicarbonate concentration and PCO2. The present study was undertaken to examine the possibility that a similar relationship between normal levels of PCO2 and plasma bicarbonate might ... | 44,886 | [
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0.2399945,
0.03278103,
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0.03876184,
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Further observations on a low-molecular-weight natriuretic substance in the urine of normal man. | Large quantities of the low-molecular-weight natriuretic material (F4), which appears after the salts when fractionated on G-25 Sephadex column, were obtained from the urine of normal man on a normal diet. The natriuretic substance in F4 was (1) untrafiltrable through a membrane with a claimed molecular-weight cut-off ... | 44,887 | [
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0.1358048,
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0.1954683,
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0.07000314,
0.1012129,
0.... |
Comparative in vitro microbiological activity and stability of cefaclor. | The in vitro activity of cefaclor was compared with that of cephalexin and cephradine. This new antibiotic was the most active of the oral agents against Haemophilus influenzae (especially non-beta-lactamase producing strains). It was also significantly more active against N. gonorrhoeae and the Enterobacteriaceae. The... | 44,910 | [
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-0.4322315,
0.003237336,
0.1910999,
-0.1391941,
0.2291874... |
The breakdown of adenine nucleotides in glucose-depleted human red cells. | 1) The rate of 2,3-bisphosphoglycerate breakdown is independent of pH value. 2) The adenine nucleotide pattern at alkaline pH values with its characteristic lowering of ATP and the accompanying accumulation of fructose-1,6-bisphosphate is caused by a relative excess of the activity of the hexokinase-phosphofructokinase... | 44,952 | [
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0.07442367,
0.6850271,
0.2835298,
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... |
Pharmacological reactions of the circular muscle of the guinea pig vas deferens. | Pharmacological responses of spiral strips prepared from the guinea pig vas deferens to various adrenergic and cholinergic agonists and autacoids were studied. On the circular muscle alpha adrenergic, muscarinic cholinergic and histaminergic receptors were identified. The responses evoked on the circular and longitudin... | 44,960 | [
0.1132282,
0.1264502,
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0.1697187,
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-0.... |
[Changes in erythrocyte lipids in severe septic states]. | In cases of major sepsis the erythrocyte lipids undergo significant change especially when there is concomitant hepatic insufficiency and this in turn lead to alteration in the blood viscosity and very probably to the genesis of disorders of coagulation. | 44,969 | [
0.1725688,
0.1472957,
0.08150458,
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0.03789196,
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0.1205748,
0.3479268,
0.1378283,
0.002040183,
-0.07916785... |
Some properties of lipase from Geotrichum asteroides. | The optimal conditions for the manifestation of the lipase activity of an enzyme preparation from the culture liquid of the fungus Geotrichum asteroides were determined. It was found that the rate of hydrolysis depends on the substrate concentration, the enzyme concentration, and the reaction time. The lipase from G. a... | 45,005 | [
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0.08022981,
0.2572455,
0.7400582,
0.4216889,
0.03854008,
... |
[Hypereosinophilic syndrome. Centrifugal annular erythema as an initial manifestation]. | Several closely related conditions make up the idopathic hypereosinophilic syndrome. This syndrome is characterized by persistent and prolonged eosinophilia. The most frequent lesions are in the hematologic, neurologic and gastrointestinal systems. A case is reported in which the initial complaint was an erythema annul... | 45,030 | [
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0.03162305,
0.09568398,
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0.02310578,
0.2042004,
0.125... |
Danger of haemodialysis using acetate dialysate in combination with a large surface area dialyser. | Large surface area, high mass transfer dialysers have recently come into widespread use, and it has been shown that they promote the loss of large amounts of bicarbonate when acetate is used in the dialysate. The present study was designed to confirm these metabolic consequences and quantitatively to compare two common... | 45,059 | [
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0.08834891,
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0.2358785,
0.00514431... |
Spontaneous labor and elective induction--a prospective randomized study. I. Effects on mother and fetus. | In a prospective randomized study spontaneous and oxytocin induced labor "for convenience" have been compared with respect to uterine activity, duration of labor, the condition of the fetus and the newborn infant. The study consists of 84 normal patients, of whom 43 were induced at full term by amniotomy and oxytocin i... | 45,068 | [
0.2310728,
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0.0320433,
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0.7105823,
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-0.2538025... |
Techniques for laparoscopy on patients with previous abdominal surgery. | Many clinicans are hesitant to perform laparoscopy on patients with previous intra-abdominal surgery, because of increased risk of hemorrhage or intestinal perforation in the presence of abdominal adhesions. Experiences and techniques used in Grady Memorial Hospital to increase the safety of laparoscopic procedures per... | 45,097 | [
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0.09085962,
-0.1988684,
0.01773726,
0.1781999,
-0.0... |
Inherent ranges of seminal prolactin in pre- and postvasectomy subjects. | Seminal immunoreactive prolactin (i prolactin) was studied in 14 healthy subjects, ages 31 +/- 2 SEM, before and after undergoing elective vassectomy for birth control. Seminal plasma was separated within 2 hours of ejaculation, and prolactin was measured in duplicate by radioimmunoassay. The difference between the pre... | 45,102 | [
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0.187386,
0.06896643,
-0.01067... |
Serum prolactin levels following intramuscular chlorpromazine: two- and three-hour response as predictors of six-hour response. | Neuroendocrine studies that examine the changes in serum prolactin levels following intramuscular (im) neuroleptics have usually monitored prolactin levels before and for 90 minutes to 3 hours after neuroleptic injection. Recent studies have suggested that this may be an inadequate period of time. In the present study,... | 45,130 | [
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0.01441078,
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0.1394356,
0.3977967,
0.2732208,
0.0685398... |
Myosin and actin containing cells in the human postnatal thymus. Ultrastructural and immunohistochemical findings in normal thymus and in myasthenia gravis. | Samples of normal human thymus of different ages (4-63 years old) were studied by immunofluorescence microscopy (using antibodies to smooth muscle myosin, to actin from the chicken gizzard, and antibodies to myosin from human striated muscle) as well as by routine electron microscopy. Thymus tissue from myasthenia grav... | 45,151 | [
0.07967734,
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0.000727422,
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0.4830061,
0.1689796,
-0.056746... |
[Studies of the antibody heterogeneity in carp (Cyprinus carpio L.). I. Electrophoretic and isoelectric spectra of anti-DNP-antibodies]. | Carp IgM as well as carp anti-DNP-antibodies migrate electrophoretically very well as a diffuse band into polyacrylamide gel of large pore size. The isoelectric spectra of the carp anti-DNP-antibodies are heterogeneous and show bands in the pI-range of 4.0 to 6.4. The activity of focused anti-DNP-antibodies could be de... | 45,163 | [
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0.5028424,
0.13745,
0.1626491,
0.04945692,
-0.1176852,
-0.07649253,... |
[Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine]. | The authors made a study of the antihistaminic properties of Pipoxizine in 20 subjects with proven histaminic hyperreactivity. The design of the trial consisted in comparing the changes of VC, FEC1, expiratory airway resistance and V50 produced by a histamine aerosol given before and after administration of Pipoxizine.... | 45,187 | [
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0.07680903,
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0.2654936,
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0.167849,
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... |
[The quality of preserved blood]. | The examinations of 30 blood samples each preserved with three Yugoslav different ACD-solutions were performed. The blood samples were stored at 2-6 degrees C and examinations were performed at the day of blood donation and after on the 7th, 14th and 21st day during the storage. Differences in hematocrit (well known di... | 45,192 | [
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0.190627,
0.4006424,
0.2797442,
0.06797209,
-0.1358586,
... |
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