title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Enterochromaffin cells as the endocrine source of gastrointestinal substance P. | Immunoreactive Substance P is localized in the intramural neural plexuses of mammalian intestine, and in endocrine cells in the intestinal mucosa which have now been identified as enterochromaffin (EC). The presence of a neurotransmitter peptide in these cells favours the hypothesis of their neuroectodermal origin. | 791,906 | [
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Integration of chemoreceptor stimuli by caudal pontile and rostral medullary sites. | Ventilatory regulation by pontile pneumotaxic and apneustic centers and by rostral medullary sites was evaluated in intercollicular decerebrate cats. Following pneumotaxic center ablation, PAco2 was significantly elevated. Moreover, in response to hypercapina or hypoxia, frequency responses were significantly diminishe... | 791,917 | [
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Chromosome segregation in Escherichia coli B/r at various growth rates. | Chromosome segregation was analyzed in three substrains of Escherichia coli B/r growing at various rates. The cultures were pulse labeled with [14C]thymidine and bound to the bottom surface of a nitrocellulose membrane filter, and the radioactivity in newborn cells released from the surface during continuous elution wi... | 791,925 | [
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Evaluation of four methods for detection of group B streptococcal colonization. | Four methods (streak plate, pour plate, selective broth, and direct fluorescent-antibody staining) were evaluated for their ability to detect group B streptococcal colonization in parturient women and their offspring. When colonization was defined as a positive culture by any method from any site, selective broth was t... | 791,966 | [
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Hemolysis-in-gel test for demonstration of Chlamydia antibodies. | Sheep erythrocytes were coated with antigens of a strain of Chlamydia trachomatis serotype D. Chlamydial antibodies in sera from patients with salpingitis or pneumonia were demonstrated by passive hemolysis in agarose gel. | 791,967 | [
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Anti-lymphokine antibody. II. Specificity of biological activity. | The present study was designed to explore the range of biologic activity of an anti-lymphokine antiserum (ALKS). This preparation, which was produced by a two-stage immunization procedure, was used to prepare Sepharose bead immunoadsorbent columns. Columns made with ALKS, but not with anti-control antiserum, could spec... | 792,334 | [
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Subpopulations of human T cells identified by receptors for immunoglobulins and mitogen responsiveness. | Human T lymphocytes in peripheral blood have been shown to have receptors for IgG (Tgamma) or IgM (Tmu). Cultured Tgamma cells do not express receptors for IgM and purified Tmu cells do not have receptors for IgG, thus they appear to be distinct T cell populations. Although the two subpopulations show similar response ... | 792,341 | [
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Simultaneous quantitation of two antigens in mixture in individual cells by microimmunofluorimetry. | Double immunofluorescence has so far only been used qualitatively. In present work the possibility of quantitative double immunofluorescence was evaluated in model systems with the ultimate goal to enable simultaneous measurements of different antigens in mixture in biological objects. In one test system a conjugate of... | 792,352 | [
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Insolubilization of protein antigens on polyacrylic plastic beads using poly-L-lysine. | A new model system for quantitation of immunofluorescence on single cells is described using poly-L-lysine (PLL) coated polyacrylic plastic beads of approximately cell sizes as carriers for protein antigen. By increasing PLL concentration on the beads increased amounts of 125I labeled antigen were attached to the parti... | 792,353 | [
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Amikacin Therapy of Urinary tract infections. | The efficacy and safety of amikacin in treatment of patients with urinary tract infections were evaluated. Underlying urologic disease was prevalent in the population studied. Amikacin was administered to 50 patients in a dosage of 7.5 mg/kg twice daily. In a subsequent study, amikacin was compared with gentamicin in t... | 792,358 | [
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Amino-acid pool composition of Saccharomyces cerevisiae as a function of growth rate and amino-acid nitrogen source. | The composition of the amino-acid pool of Saccharomyces cerevisiae is markedly influenced by the amino-acid nitrogen source. The yeast tends to accumulate the amino acid supplied and those closely related to it metabolically. A relatively high concentration of glutamic acid is maintained in the pools of all cultures ir... | 792,385 | [
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Thenar "H-flap" for fingertip injuries. | Many severe fingertip injuries may be successfully treated by a thenar H-flap (Fig. 3). It is recommended to cover protruding bone in younger patients. The flap must be detached in 10 to 14 days. The use of the H-flap design permits all wounds to be closed between the first and second stages of surgery and leaves a pai... | 792,463 | [
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[Benign, diffuse external otitis]. | A review of the literature on benign diffuse external otitis was done to throw light on the problems of pathogenesis, etiological factors, and various forms of treatment. A prospective study done on normal adult ear canals and a prospective study of 26 new cases of benign external otitis was done according to clinical ... | 792,467 | [
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Temperature gradients and prediction of flap viability. | This study validates a simple clinical method used to determine optimum time for flap transference. Temperature was used as an indirect measurement to determine blood flow. By means of a needle thermocouple, temperature differences in a variety of flaps were measured. Differences between the base and most distal portio... | 792,468 | [
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Routine blood cultures from febrile outpatients. Use in detecting bacteremia. | Of 565 febrile patients examined in the emergency room of a metropolitan hospital, 210 had blood samples cultured (37.1%). Bacteremia was present in 9 of 86 patients who were admitted to the hospital but in only one of 124 patients who were not admitted (P less than .005). Thus, approximately 5% of febrile adult outpat... | 792,487 | [
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Cardiovascular responses of hyperactive children to methylphenidate. | Heart rate, blood pressure, and oxygen consumption were measured in 27 hyperactive children during rest, exercise, and recovery, once taking placebo and again taking methylphenidate hydrochloride. Half were measured first taking the drug and half first taking the placebo. Twenty-three matched controls were also measure... | 792,490 | [
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Relationship of causative factors in spontaneous regression of cancer to immunologic factors possibly effective in cancer. | In a book written by Everson and Cole (1966) on spontaneous regression 176 examples of the phenomenon were encountered in the medical literature from 1900 to 1964, supplemented by cases referred by friends. No common denominator of explanations were found. Various types of trauma (e.g., biopsy, incomplete excision), t... | 792,571 | [
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[Interaction between the systems involved in fast pain perception and in slow, persistent pain (author's transl)]. | A single pinprick triggers both a pang, the "1st pain" and after a pause of 0.5 s, a spreading burning feeling, the "2nd pain". The 2nd pain is delayed because it is conducted by unmyelinated C-fibers at a rate of less than 1 m/s, 20 times slower than conduction of the 1st pain. In the spino-thalamic tract the myelinat... | 792,594 | [
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Alternatives in nasal reconstruction ("five flaps and a graft"). | Five pedicle flaps and one auricular composite graft deserve increased use and attention in nasal reconstructive surgery. All have in common the high possibility of superior functional and esthetic results while requiring the payment of a minimum penalty of tissue sacrifice. A composite graft of conchal cartilage and a... | 792,596 | [
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International standard (C.C.I.T.T.) for transmitting biomedical analogue and digital data on the public telephone network. | Analogue transmission of biomedical signals over the public telephone network has advantages from the economic point of view over digitalized transmission. This paper deals with the special problems encountered with the transmission of biomedical signals. Furthermore, the new international transmission standard C.C.I.T... | 792,674 | [
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Medical applications of analogue and digital telephone data links. | The increasing use of digital computer techniques for the analysis of signals such as the EEG, ECG, plethysmograms and cardiac output curves has led to the use of multichannel analogue frequency modulation telephone data links in the forward direction from the patient to the computer and digital links in the return dir... | 792,675 | [
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Isolation of lambda prophage mutants defective in structural genes: their use for the study of bacteriophage morphogenesis. | Mutants of coliphage lambda defective in structural genes were isolated and characterized. The isolation method consisted in lysogenizing bacteria with mutagenized phage and testing for inability to form plaques after heat induction. The mutants were propagated as prophages in the lysogens. Mutants in the region of the... | 792,680 | [
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Isolation and characterization of phi80dgal transducing phages that carry gal operator-promoter insertion mutations. | phi80dgal transducing bacteriophages have been isolated by the F-fusion technique of Press et al. (1971) and gal-operator-promoter insertion mutations have been introduced by homogenate formation. Five different phi80dgal isolates have been studied in more detail. One of the phi80 phages transduces the gal operon and g... | 792,683 | [
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Cloned synthetic lac operator DNA is biologically active. | A chemically synthesised duplex DNA fragment containing the sequence of the lac operator was cloned in E. coli using the vehicle pMB9. Clones containing lac-pMB9 hybrid DNA produced beta-galactosidase constitutively and the hybrid DNA bound the lac repressor specifically. | 792,711 | [
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[On-line analysis of the exercise electrocardiogram]. | A programme of on-line automated analysis of ECG exercise graphs relative to the CB5 derivation is described. The various operations may be subdivided into the following phases: 1) performance; 2) mean complex; 3) identification; 4) calculation and print-out of parameters; 5) filing. Automatic analysis of exercise ECG'... | 792,727 | [
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[A program of combined ECG and VCG automatic diagnosis. Note I. The atriogram]. | In this paper a new computer aided ECG and VCG data handling is analized. It is based on an optimum estimation of dipole moment, which is used as the main diagnosis parameter. Already known diagnostical methods (available in present literature) are compared with this new technique. The available diagnostical range has ... | 792,729 | [
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[Plan for installation of an automatic system of analysis of electrocardiograms for a group of hospitals and a regional cardiological record office]. | In view of the present state of the Central ECG Department serving the "San Giovanni" group of hospitals in Turin and in consideration of the ever growing number of ECG's required daily, a reorganization of the department has become necessary. Such a reorganization must be based on the latest facilities offered by elec... | 792,730 | [
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[Data on experience with automated diagnostic systems]. | This study highlights the various parameters considered for experimenting automatic equipment correctly. By applying such parameters to experiments with the "Sicard" system (Siemens) for automatic ECG reading, the usefulness of the system for its declared purpose, i.e. mass screening and epidemiological research, has b... | 792,733 | [
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... |
[Controlled clinical trial of parsalmide, a drug with analgesic and anti-inflammatory activity]. | A controlled clinical trial of the anti-inflammatory, analgesic, muscle-relaxing and anxiolytic activity of a new compound (parsalmide) was compared with that of phenybutazone in 40 patients with acute or exacerbated inflammatory or degenerative processes randomly distributed into two treatment groups. Parsalmide was m... | 792,737 | [
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The calcifying epithelial odontogenic tumor. A review and analysis of 113 cases. | A review of the world literature has revealed 113 cases of the calcifying epithelial odontogenic tumor. The clinical, radiographic, and histopathologic features are analyzed. Various treatments that have been carried out are related to the frequency of recurrence. The theories of histogenesis are discussed and an attem... | 792,760 | [
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The clinical problems of dosage and the route of administration of antilymphocyte globulin. | The production and quality control of ALG are outlined. The advantages and disadvantages of the various routes of administration of ALG are discussed. We tend to use a short duration high dose course of ALG in renal transplantation, myasthenia gravis and polyarteritis nodosa. | 792,846 | [
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Controlled trial of antilymphocyte globulin in cadaveric transplantation. | Since January 1974, alternate cadaveric renal transplants were treated with antilymphocyte globulin (Behringwerke) om addotopm to prednisone and azathioprine. Thirty patients were treated in this way. 53% of patients receiving ALG had a functioning graft at six months as opposed to 40% in the control group. This differ... | 792,850 | [
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Steroids in the assessment of prenatal development. | Methods for identifying the fetus at risk and monitoring fetal well-being as pregnancy progresses are now an established part of prenatal care in the Western World. In this short review the use of steroids in the assessment of prenatal development is discussed. The metabolism of oestrogens, progestogens, corticosteroid... | 792,854 | [
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Histological investigation of the etiology of capsule contracture following augmentation mammaplasty. | Sections obtained from contracted breast capsules were examined by light and electron microscopy. We observed the presence of multiple areas of a particulate foreign material, consistent with the appearance of droplets of dimethylpolysiloxane. An active foreign-body reaction was observed at the interface of the capsule... | 792,918 | [
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A dermal flap for carotid artery protection. | We describe a dermal flap for use in protecting an especially vulnerable carotid artery from rupture after a radical neck dissection. We have used this flap successfully in 3 patients in the last 5 years. | 792,919 | [
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Effect of 13-Nle-motilin in postoperative ileus patients: a double-blind trial. | In this study, the effect of 13-norleucine motilin (13-Nle-M) on post-cholecystectomy ileus was assessed in 6 female patients. 13-Nle-M given by continuous i.v. infusion (0.4 mug/kg-h) on the second and third day following surgery did not influence the manifestation and duration of intestinal paralysis in comparison to... | 792,985 | [
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The efficacy, as modified by the circadian rhythm of salbutamol administered by different routes. | Fourteen asthmatic outpatients participated in a total of 16 trials with salbutamol administered by different routes. Drug dosage was one 4-mg tablet, of two inhalations of 100 mug of salbutamol aerosol or a combination of both, four times daily. During the trial the patients measured their peak expiratory flow (PEF) e... | 792,993 | [
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[Complications of catheterization of the subclavian vein and their prevention]. | The frequency of complications related with catheterization of the subclavian vein was 16.2%. The most hazardous complications were as follows: the pulmonary artery embolism, migration of a catheter in the venous bed and thrombosis of the catheterized vein. The proper selection of indications, careful observation of th... | 793,160 | [
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[Macrocytosis in renal transplant patients (author's transl)]. | Since macrocytosis was observed in a high percentage of our renal transplant patients, a follow-up study was carried out on 36 patients with determination of the mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and haemoglobin concentration (MCHC). These parameters were determined monthly for periods o... | 793,185 | [
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... |
[Clinic of the upper cervical spine and review of the medical history of the regional osteology (author's transl)]. | After a brief review of the systematic clinical work up of this region within our century, the medical history of the osteology of the occipito-cervical junction is given special attention. It is looked upon the illustrations of the first printed anatomical textbooks that are linked with such famous names as Berengario... | 793,227 | [
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[The history of the pathological anatomy in the Soviet Union (author's transl)]. | The development of the pathological anatomy in Russia and in the Soviet Union is described, beginning from the foundation of the first prosecture in 1707 up to the present time. In the first half of the 18th century, this special branch was supported by Peter I, whereas it developed very slowly in the second half of th... | 793,255 | [
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Experimental restoration of skin defects with Surgicel soaked in blood. | Skin defects of full thickness were produced in 15 rabbits. The wounds were covered with Surgicel soaked in the animal's own blood and fixed at the edges with Histoacryl-N-Blau adhesive. A gradual epithelization took place under the covering layer. The method is suggested as an emergency measure in case of serious burn... | 793,265 | [
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Genetic mapping of the K1 and K4 antigens (L) of Escherichia coli. Non-allelism of K(L) antigens with K antigens of O8:K27(A), O8:K8(L) and O9:K57(B). | Escherichia donor strains having antigen K1(L) or K4(L) transfer these K antigens to recipient cells at a genetic locus (kps A) similar to that of K10(L) and K54(L) linked to ser A. In crosses between the K10 donor strain and recipient strains O8:K8(L), O8:K27(A) and O9:K57(B) all recombinants which inherit donor K ant... | 793,292 | [
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Immunological in vitro parameters in patients with multiple sclerosis and in normal individuals. | The general immunological capacity of 40 patients with multiple sclerosis has been evaluated with lymphocyte transformation test including both mitogens (PHA and PWM) and antigens (PPD, Candida albicans, Staph. aureus and E. coli). Determination of T and B cells was performed by E-, EAC-rosetting and immunofluorescence... | 793,300 | [
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Basic targets and the different epilepsies. | The follow up of 49 stereotactically operated epileptics is graphically demonstrated and the 79 operations in basic targets within the amygdala and the area of the anterior pole of the thalamus are described. The patients had valuable gaining in 80%; The continued developement of stereotactic methods in the future is u... | 793,310 | [
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Effects of stereotactic lesions in intractable epilepsy. | The eras of surgical treatment of epilepsy are described and experience with the epilepsy operations, especially those obtained in the course of temporal epilepsy operations, and stereotactic attempts based on multielectrode EEG investigations, and ES. Classical, exposure and resection still seems adequate whilst stere... | 793,312 | [
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The present view of RES and shock. | Conclusive evidence emphasizes the need for a functionally intact RES function in shock states and in the critically ill patient. Effort must be made to restore and maintain homeostasis also with regard to the RES. RES-research must be intensified in order to define the exact mechanism of the post-traumatic RES depress... | 793,351 | [
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Theoretical foundation of the medieval preparations of urinary derivatives. | It has been recently brought to light that the Chinese, as early as 1025 A.D., had already devised a preparation which would extract hormones from urine. This paper attempts to trace the development of Chinese medical thought, from 25 A.D., which had led to such a sophisticated preparation. | 793,375 | [
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Titles in the medicolegal field: a proposal for reform. | One of the most readily apparent weaknesses in the field of medicolegal studies has been our inability to develop consistent and lexicographically defensible descriptive titles for the field itself. In this Article, Professor William J. Curran offers an analysis of the historical roots of the terminology which has been... | 793,384 | [
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An artificial anterior chamber. | Corneas for penetrating keratoplasty that have been excised from the globe for storage ordinarily require punching of the donor tissue from the posterior surface. They may be trephined from the anterior surface when they are mounted on an instrument that forms a seal around the scleral rim of the excised cornea, allowi... | 793,400 | [
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Study of E rosettes, serum IgE and eosinophilia in asthmatic children. | In this study active and total E rosettes in asthmatic children were comparable to those in healthy children and healthy adults. There were no interrelations among E rosettes, serum IgE levels and total eosinophil counts. | 793,456 | [
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[Meconium aspiration syndrome. Two cases treated with continuous positive airway pressure (author's transl)]. | Two cases of Meconium Aspiration Syndrome successfully treated with CPAP are presented. In both patients the introduction CPAP enhanced arterial oxygenation. The A-a DO2 showed a decrease of 57 and 228 mm Hg respectively. After the introduction of CPAP it was possible to decrease the enviromental oxygen concentration a... | 793,463 | [
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[Distribution and properties of streptomycin-resistant clones in a population of freshly isolated Shigella sonnei strains]. | It was found that the rate of emergence of streptomycin resistant clones in the populations of fresh isolates of Shigella Zonne amounted to 10(-6)--10(-4). Such streptomycin resistant clones masked streptomycin resistance of the initial Shigella population. The main biological properties of the streptomycin resistant c... | 793,512 | [
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Calyceal-cutaneous fistulae in renal transplant patients. | Calyceal-cutaneous fistula is a serious sequela of renal transplantation occurring in approximately 3% of allografts. This complication occurred in 12% of allografts with multiple renal arteries. A localized area of poor parenchymal perfusion involving less than one-eighth of the kidney was noted at the time of transpl... | 793,542 | [
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Gallium citrate Ga 67 scanning: clinical usefulness in lymphoma patients. | Gallium citrate Ga 67 (67Ga) scans were performed in 50 consecutive lymphoma patients who underwent routine staging. The overall accuracy of 67Ga scans was greater than 80% for all nodal sites except the spleen (68%). Sensitivity was greater than 88% in the neck and mediastinum, 67% in the abdomen-pelvis, and 33% for t... | 793,551 | [
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Botulinum antitoxins and antibacterial IgM and IgG antibodies in sera of persons immunized with botulinum polytoxoid combined with cholera vaccine. I. Response to botulinum toxoid. | Two groups of subjects were immunized with combined vaccine containing aluminum hydroxide-adsorbed botulinum toxoids, types A, B, and E, and 4 mld of formaldehyde-inactivated V. cholerae Inaba and Ogawa organisms. The first group included laboratory workers who were previously immunized against cholera and had professi... | 793,566 | [
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0.2535326,
0.5008882,
0.2919546,
-0.159289,
0.1... |
The accessibility of protein-bound dinitrophenyl groups to univalent fragments of anti-dinitrophenyl antibody. | A series of N-(N-dinitrophenylaminoalkyl)maleimides were sythesized with alkyl-chain lengths of two, four and six carbon atoms. When these compounds reacted with the thiol group of mercaptalbumin, the tryptophan fluorescence of the protein was quenched. This change in fluorescence was used to determine the rate of reac... | 793,583 | [
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Smooth-muscle-associated contractile protein in renal mesenchymal tumour cells and in transformed cells from DMN-injected rats. | Cryostat sections and established in vitro cultures of dimethylnitrosamine(DMN)-induced renal mesenchymal tumours and monolayer cultures of transformed kidney cells derived from rats treated with a carcinogenic dose of DMN were examined by indirect immunofluorescence with human serum containing smooth muscle antibody. ... | 793,609 | [
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Conformational changes of 30S ribosomes measured by intrinsic and extrinsic fluorescence. | The intrinsic tryptophan fluorescence and the fluorescence of N-(3-pyrene)maleimide, a covalently bound sulfhydryl-specific extrinsic probe, have been used to study the conformation of the 30S ribosomal subunit of Escherichia coli. (a) The tryptophan fluorescenct spectrum of the free ribosomal proteins is shifted to sh... | 793,614 | [
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Rifampicin and chloramphenicol effects on DNA replication in ultraviolet-damaged Escherichia coli B/r WP2 thy trp. | The antibiotic rifampicin, which blocks specifically RNA synthesis, limited DNA replication in Escherichia coli strain B/r WP2 thy trp after an increase of about 50%, when added to the incubation medium at the time of replication initiation after ultraviolet fluences of 20 J/m2... | 793,626 | [
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Freeze-fracture ultrastructural alterations induced by filipin, pimaricin, nystatin and amphotericin B in the plasmia membranes of Epidermophyton, Saccharomyces and red complex-induced membrane lesions. | The effects of chemically different polyenes on fungal membranes (Epidermaphyton floccosum, a human pathogenic fungus, and Saccharomyces cerevisiae) and human red blood cell membranes were studied by freeze-fracture electron microscopy in order to elucidate the interaction of these antibiotics with ergosterol. Each typ... | 793,632 | [
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Hypertension after renal transplantation. | The incidence of hypertension (mean diastolic pressure above 90 mm Hg) was evaluated in 85 patients with renal transplants whose follow-up ranged from 3 to 84 months. Bilateral nephrectomy had been performed in 80 recipients. The proportion of hypertensive subjects rose during the first three months, subsequently stabi... | 793,675 | [
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The mouse inoculation test in rabies diagnosis: early diagnosis in mice during the incubation period. | Brain tissue from 64 rabies suspect specimens were inoculated intracerebrally into twenty 9-12 gm adult Swiss white mice. Two mice from each specimen were killed on specific days postinoculation and examined for the presence of rabies virus by the fluorescent antibody staining technique. In this way a positive diagnosi... | 793,696 | [
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A direct fluorescent antibody test for large spirochetes in swine dysentery using hyperimmunized swine serum. | A direct fluorescent antibody test was developed for the identification of large spirochetes which are considered to be the cause of swine dysentery. Sera from swine which had recovered from swine dysentery and had been hyperimmunized by the intravenous and intraperitoneal injection of filtered spirochetes were used fo... | 793,697 | [
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Evaluation of a DNA polymerase-deficient mutant of E. coli for the rapid detection of carcinogens. | Differential growth inhibition of two E. coli cultures was evaluated as a rapid screening technique for chemical carcinogens. Of the carcinogens tested, only "direct acting" carcinogens produced positive results. Furthermore, this test is not a quantitative assay in that neither was a dose--response relationship seen n... | 793,736 | [
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Effect of topically applied acidulated phosphate fluoride on dental caries. | A 4-year clinical trial was conducted to determine the effect on dental caries incidence of the use of acidulated phosphate fluoride (APF 1.23%). 1,653 Egyptian schoolchildren aged 8 years started the trial. Dental caries was assessed annually by clinical examinations. 1,027 children completed the study. After 4 years,... | 793,766 | [
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0.14... |
Products of soil microorganisms in relation to plant growth. | A survey has been made of the range and activity of the organic products of soil microorganisms which have a direct influence on plant growth. Microbial metabolites which effect plants indirectly by the modification of the soil environment are also reviewed. The sources of substrates for the production of metabolites i... | 793,776 | [
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Double-blind trial of a long-acting bronchodilator preparation ("Nethaprin Dospan") in bronchospastic disease. | A double-blind, placebo-controlled, crossover study was carried out in 48 patients with bronchospastic disease to assess the efficacy of a long-acting bronchodilator preparation ("Nethaprin Dospan") containing etafedrine hydrochloride, bufylline, doxylamine succinate and phenylephrine. Patients received 1 tablet nightl... | 793,781 | [
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Differential rates of sister chromatid exchanges between euchromatin and heterochromatin. | In two rodent species, the Chinese hamster and the montane vole (Microtus montanus), the rate of sister chromatid exchange was lower in constitutive heterochromatin than in euchromatin. | 793,794 | [
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The inheritance of radiation induced semi-sterility in Rhodnius prolixus. | Eggs from crosses of 40 adult male R. prolixus irradiated with 6K rad gamma-rays with normal females had a mean fertility of 23.9%, only 2 crosses being completely sterile. The 86 F1 progeny of both sexes, when outcrossed with normal mates, had a mean egg fertility of 12.6;, and 43 of these matings were completely ster... | 793,795 | [
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[The method of preparation for VMK-crowns]. | In a clinical study, follow-ups were made in 259 tangentially prepared VMK crowns. In 49,4 per cent of the cases, inflammatory changes of the marginal gingiva were found, 34.5 per cent discolorations were observed in the same region. Measurements of the marginal thickness of those 68 VMK crowns prepared in a dental lab... | 793,834 | [
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Comparative study of metoprolol and alpha-methyldopa in untreated essential hypertension. | The hypotensive actions of metoprolol and alpha-methyldopa have been compared in 37 men with previously untreated essential hypertension; 36 belonged to stage 1 and 1 to stage 2 of the WHO classification. After four weeks of placebo treatment the patients were randomly allocated to treatment with either of the two drug... | 793,848 | [
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Results of potency tests of a vaccine against Cl. botulinum type C by different methods. | The potency of vaccine against Cl. botulinum type C was tested comparatively in mice, guinea pigs and mink, using the test methods employed in the United States, Great Britain and Sweden. Additionally the capacity to withstand challenge to toxin in ferrets was investigated. All species of laboratory animals proved to b... | 793,914 | [
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Testing the heterogeneity of F values: a suggestion and a correction. | The use of a pair of populations removes the problems posed by a structured phylogeny (pointed out by A. ROBERTSON) and permits the application of the original test of LEWONTIN and KRAKAUER. In the case of 2n populations studied a suggestion is made to use only n pairs in such a way that no population appears in more t... | 793,925 | [
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[Transforming activity of Escherichia coli DNA fragments obtained following endonucleolytic splitting by EcoRI restrictase]. | Escherichia coli DNA with molecular weight of 20 - 10(6) daltons was digested by restriction endonuclease EcoR1, and the transforming activity of resctricts was studied. The transforming activity of restricts for two markers (Leu and Arg) was 2-5 fold increased, for two other markers (Thr and His) was not changed, and ... | 793,931 | [
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[Clinical significance of sperm pathogens in fertility disorders]. | The reasons for systematic microbial examinations of human ejaculates are discussed. The exact establishment of an association between bacteria isolated from human ejaculates and infertility is very difficult. There are several hints for such an association in the case of different micoplasmas though there is no clear-... | 793,968 | [
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Mutagenicity and possible carcinogenicity of hair colourants and constituents. | Skin painting experiments showed that two semi-permanent hair colorants applied at low concentrations caused an early appearance of tumours in two strains of mice. Both colorants were mutagenic in S. typhimurium and further investigation revealed that three categories of hair colorant contained mutagenic constitutents. | 793,979 | [
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Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice. | The increased endotoxin lethality in mice pretreated with BCG was not observed in mice pretreated with trehalose-6,6'-dimycolate instead of BCG. | 793,994 | [
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Ultrastructural identification of cells storing pancreatic-type glucagon in dog stomach. | The oxyntic mucosa of the dog stomach is rich in cells storing pancreatic-type glucagon. The cells were identified by immunocytochemistry and found to be indistinguishable from pancreatic A cells in the electron microscope. Ultrastructural identification of the immunoreactive cells was accomplished by the use of consec... | 794,042 | [
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... |
Survey for Salmonellae in porcine bile and cecums and on equipment surfaces in an Ohio abattoir. | Porcine bile samples and cecal swabbings and environmental swabbings collected from an abattoir in Columbus, Oh, were examined for salmonellae. Of 40 cecal swabbings, 6 were culture-positive for Salmonella choleraesuis and 2 of 25 swabbings of surfaces that were in contact with edible products were culture-positive for... | 794,045 | [
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Conformational changes and reassociation properties of small subunits of Escherichia coli ribosomes. | Studies on the reassociation of ribosomal subunits from Escherichia coli were carried out using an ultracentrifuge equipped with a UV absorption scanner, and the conformational changes of ribosomal subunits were followed by circular dichroism measurements. Reassociation between the fractionated 30S and 50 S subunits wa... | 794,062 | [
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... |
Predicting the response of hyperkinetic children to stimulant drugs: a review. | The present review examines 36 previous research reports involving over 1,400 hyperkinetic children in an effort to determine which variables have proven useful in predicting which hyperkinetic children will respond favorably to stimulant drugs. The research is summarized under eight types of predictor variables: (1) p... | 794,087 | [
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... |
Marginal leakage with different composite restorative materials: effect of restorative techniques. | The degrees of marginal leakage was tested for different restorative techniques with use of both ultraviolet-polymerized and cold-curing resins. All the materials tested showed severe marginal leakage when applied as conventional butt joint restorations. When the restorations were extended onto peripheral etched enamel... | 794,089 | [
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Field trial of an inactivated Mycoplasma pneumoniae vaccine. I. Vaccine efficacy. | The efficacy of an inactivated Mycoplasma pneumoniae vaccine was evaluated in a double-blind study of 7,861 Marine Corps recruits at Parris Island, South Carolina. Vaccine was administered to half for the volunteers in a 1-ml dose by a jet-injection device, and phosphate-buffered saline was administered similarly to co... | 794,422 | [
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0.02377419,
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0.04652049,
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0.06799934,
-0.1812544,
0.008999315,
0.4457604,
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-0.1001... |
Is there a reciprocal relationship between symptoms and affect in asthma? | This is a hypothesis-seeking case study. It is the product of naturalistic research on one asthmatic patient seen 212 times in individual psychotherapy over a period of 32 months. Both retrospective and prospective data were gathered, the prospective phase beginning about halfway into the therapy. Clinical vignettes ar... | 794,442 | [
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0.172766,
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... |
Polyglutamyl and polylysyl derivatives of the lysine analogues of folic acid and homofolic acid. | A series of Nepsilon-poly-alpha-glutamyl and Nepsilon-polylysyl derivatives of Nalpha-pteroyllysine and Nalpha-homopteroyllysine, analogues of the naturally occurring gamma-polyglutamyl forms of folate, was prepared and tested as substrates for dihydrofolate reductase and as substrates and inhibitors of thymidylate syn... | 794,472 | [
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0.3555844,
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0.2410176,
0.287128,
0.2645887,
0.03382396,
0.03985332... |
Tumor-associated macrophages as the primary source of lysozyme in the urine of mice bearing GPC-11, a transplantable reticulum cell sarcoma. | Large amounts of lysozyme accumulated in the serum and urine of (NZB X BALB/c)F1 mice with GPC-11, a transplantable reticulum cell sarcoma, type A. We separated GPC-11 cell suspensions on 20% Ludox HS gradients. (HS is one of the nine general grades of Ludox offered by du Pont de Nemours & Co., Wilmington, Del.) We... | 794,500 | [
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From Quonset hut to naval hospital. The story of an alcoholism rehabilitation service. | The history and treatment methods of the first Navy Alcoholism Rehabilitation Service are described. | 794,590 | [
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0.0265594,
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0.06885991,
0.1061096,
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0.1581868,
0.06036536,
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The disease concept of alcoholism revisited. | The history of the conception of alcoholism as a disease is outlined. Recent opposition to that conception and the specific reasons therefor are discussed. On the basis that addiction constitutes a disablement in the medical sense, it is concluded that alcoholism is properly defined as a disease. | 794,591 | [
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0.05991787,
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The molecular events involved in the induction of petite yeast mutants by fluorinated pyrimidines. | The fluorinated pyrimidines 5-fluorouracil (5FU) and 5-fluorocytosine (5FC) induce the cytoplasmic petite mutation in the yeast Saccharomyces cerevisiae with high efficiency. It was found that in order to induce the mutation, 5FC must first be deaminated to 5FU. However, mutagenesis does not depend on the further conve... | 794,690 | [
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0.3008328,
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0.06652943,
0.4152893,
0.3105482,
0.1009685,
-0.30... |
A comparative study of different experimental protocols for mutagenesis assays with the 9-azaguanine resistance system in cultured Chinese hamster cells. | Both spontaneous and EMS-induced mutant frequencies were determined in cultured cells from V79 Chinese hamsters using three different experimental protocols. After optimal expression time was attained, mutation frequencies only remained constant when a protocol was used in whcih the cell density was maintained below cr... | 794,707 | [
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0.3823732,
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0.2330092,
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0.4713591,
0.5004818,
0.06143287,
0.1293831... |
Interim report on clinic intake and safety data collected from 17 NIDA-funded naltrexone studies. | In 17 studies of naltrexone, a totoal of 1,536 patients had been logged in as potential study subjects as of February 29, 1976. Of these, 883 had been started on study medication, including 107 on placebo as controls. A relatively high rate of attrition was seen in all studies over the first two months of study medicat... | 794,717 | [
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0.08031835,
0.2902775,
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0.2658569,
-0.318... |
Effect of photoperiod on gonadotropin releasing hormone-induced LH release in the immature rat. | Female rats raised from birth under a light/dark (LD) or constant light (LL) regimen were given injections at either 24, 29, 33 or 35 days of age of either 5 IU PMSG or 0.1 ml saline. Two days following PMSG or saline injection, the rats were given injections of either 1,000 ng synthetic gonadotropin releasing hormone ... | 794,754 | [
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0.07365573,
0.132295,
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0.3689751,
0.224076,
0.06371853,
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Study on the structure-function relationship of polynucleotide phosphorylase: model of a proteolytic degraded polynucleotide phosphorylase. | It is already known that modification of E. coli polynucleotide phosphorylase by endogenous proteolysis induces drastic changes in both phosphorolysis and polymerisation reactions. The structural parameters of the proteolysed polynucleotide phosphorylase are described. The phosphorolysis of polynucleotide, which is qui... | 794,831 | [
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0.04078687,
0.2481714,
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0.002928337,
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0.301975,
0.3653108,
0.2730708,
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... |
Kinetic studies on the cleavage of adenovirus DNA by restriction endonuclease Eco RI. | The kinetics of cleavage of DNA from Adenovirus Type 1 (Ad1), Type 5 (Ad5) and Type 6 (Ad6) by restriction endonuclease EcoRI was investigated by quantitative evaluation of the fluorescence from ethidium stained DNA fragments separated on agarose gels. The apparent rate constants of cleavage at different cleavage sites... | 794,836 | [
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0.1895247,
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0.5445958,
0.08432815,
0.2552854,
0.507799,
0.2349878,
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... |
The nucleotide sequence of asparagine tRNA from Escherichia coli. | The nucleotide seuquence of Escherichia coli asparagine tRNA was determined to be pU-C-C-U-C-U-G-s4U-A-G-U-U-C-A-G-D-C-G-G-D-A-G-A-A-C-G-G-C-G-G-A-C-U-Q-U-U-t6A-A-phi-C-C-G-U-A-U-m G-U-C-A-C-U-G-G-T-phi-C-G-A-G-U-C-C-A-G-U-C-A-G-A-G-G-A-G-C-C-AOH. Its D-stem and D-loop have almost the same sequence as Escherichia coli ... | 794,837 | [
0.1469108,
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0.09320416,
0.01264212,
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0.1457024,
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0.540487,
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... |
Effect of immunosuppressors, anticoagulants and antiphlogistic drugs on experimental Masugi glomerulonephritis: I-imuran. | The effect of Imuran on experimental Masugi glomerulonephritis was checked in rabbits. The animals were grouped in biologically most similar pairs: one of the mates was treated with Imuran (4 or 8 mg/kg daily) the other served as control. Clinical and laboratory investigations were supplemented by histological and immu... | 794,857 | [
0.06903034,
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... |
[A pediculate commissural flap. Its use in the closing of orostoma in irradiated areas]. | The arch-like pediculated commissural flap utilizes the cutaneous layer of the lower lip, the chin and the sub-mental region which are usually not affected by radiation fields in tumours of the longue, the floor and the gum. Its vascularisation which at first sight appears paradoxical, results from anastomoses between ... | 794,991 | [
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0.0480122,
0.07936874,
0.2164695,
0.5590785,
0.03201258,
0.1195445,
... |
Antimicrobial effect of four different toothpastes. | The study was undertaken to evaluate the antimicrobial effect of a commercial toothpaste, claimed to contain active chlorhexidine gluconate. Two traditional toothpastes and a 0.5% chlorhexidine gel were used as negative and positive control pastes. To exclude the effect of mechanical cleaning, all the agents were appli... | 794,996 | [
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0.1400233,
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0.1671091,
0.2... |
Colonization and clinical superinfection with gram-negative bacilli in influenza. | Among 197 influenza A patients admitted to Roslagstull Hospital, abundant growth of gram-negative bacilli was found in 74 cases (38%). When assays for antibodies with the patients own strains as antigen were performed on paired sera with the indirect immunofluorescence technique, titre increases were obtained in 21 out... | 795,003 | [
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0.2678166,
0.0680702,
0.1069712,... |
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