title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Therapeutic ureteral obstruction and renal artery embolization. | Two relatively unique techniques have been used in 4 cases to treat gross hematuria that might otherwise have resulted in nephrectomies. The techniques include ureteral obstruction with a Fogarty catheter and renal artery embolization. | 799,171 | [
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Prolonged survival from renal cell carcinoma after renal allotransplantation. | We herein report on a patient who was subjected to bilateral nephrectomy in the course of treating unilateral renal cell carcinoma. The patient has survived for 3 1/2 years free of tumor and has had normal renal function after a 4 antigen match cadaver kidney allograft. | 799,173 | [
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A modified method of harvesting M. leprae from foot-pads of mice. | A modified technique of harvesting M. leprae from the foot-pads of mice is described. The method is simple and takes less time for its performance than the conventional techniques. The yield of bacilli is also better. No difficulties have been encountered in its application in these laboratories. | 799,206 | [
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Bacillaemia in reactive states of leprosy. | 35 cases of lepromatous and near-lepromatous cases of laprosy in Reaction have been investigated for the presence of acid-fast bacilli in blood at the height of the reaction as well as at its subsidence. Only 3 cases exhibited bacillaemia during reaction. It is therefore unlikely that dissemination of the disease is ac... | 799,213 | [
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Revertants of double opal-mutants of bacteriophage T4. | Revertants of double opal-mutants of bacteriophage T4 have been obtained. The properties of these revertants suggest that reversion of double opal-mutants is effected by the activity of some gent-suppressor appeared in the phage genome. Restriction of these revertants by streptomycin-resistant bacterial strains shows t... | 799,254 | [
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Plasma inhibitors of the Hageman factor dependent pathways. | The Hageman factor dependent pathways are influenced by several control proteins which modulate the extent of activation and biologic activity of these enzyme substrates (Fig. 1). C1 INH plays a prominent role by acting at the common initiating step for all three Hageman factor dependent systems and its deficiency prod... | 799,348 | [
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[(Pro)insulin biosynthesis of isolated islands of Langerhans in the sand rat and Wistar rat]. | Sand rats develop a diabetes-like syndrome, connected with temporary hyperinsulinism, when fed a rat laboratory chow diet. The conversion of proinsulin to insulin is not disturbed in these animals. Sand rat islets do not secrete newly synthesized (pro) insulin preferentially. Time course and glucose response of [3H]-le... | 799,454 | [
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[Primary hypertension of the lesser circulation]. | The article presents a survey of the literature data and findings of the author's own investigations concerning various aspects of primary pulmonary hypertension (PPH). PPH -- is a polyentiological suffering. As a nosological form it was described in the fifities. There are two forms of PPH: congenital and acquired. In... | 799,495 | [
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[Experimental anti-arrhythmic action of perhexiline]. | The antiarrhythmic action of Perhexiline phosphate, in doses of 3 and 6 mg/kg on various experimental cardiac arrhytmias and on the physiological properties of the atrial myocardium has been studied in the anesthetized dog. Its action in concentrations of 3 and 6 mcg/ml on the transmembrane action potentials in isolate... | 799,493 | [
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Clinical evaluation of atenolol in hypertension. | 1. Atenolol (ICI 66.082, Tenormin) is a new beta-adrenoreceptor-blocking agent, devoid of intrinsic sympathomimetic and membrane-stabilizing properties. It does not cross the blood-brain barrier. 2. Atenolol given to hypertensive patients in initial open trials reduced arterial blood pressure significantly. 3. A double... | 799,559 | [
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A simple method for detection and analysis of carcinogenic nitrofuran compounds and their metabolites by combining chromatography and spot mutation tests. | A simple, sensitive, and convenient method combining thin-layer chromatography and a spot test for mutagenicity of Salmonella typhimurium TA100 was utilized for the analysis of urine of rats fed N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT), a potent experimental urinary bladder carcinogen. Three metabolites of... | 799,604 | [
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Wilhelm Dilthey forerunner of humanist social thought. | Humanist sociology is as a meadow in the forest of positivist science. Much of this space was cleared by Wilhelm Dilthey, not only through his attack on the fundamental assumptions of positivism, but also through his formulation of a critical method by which the works of free human consciousness could be understood. Th... | 799,624 | [
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Spontaneous regression of genitourinary cancers. | In genitourinary cancers, spontaneous regression has occurred in few instances and for reasons unknown. Although it cannot be denied that nephrectomy may have promoted regression of distant metastases in some cases, this is an unproved relationship and, in any event, an extremely rare sequence. | 799,757 | [
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Spontaneous remission in Burkitt's lymphoma. | Three cases of spontaneous regression of Burkitt's lymphoma are reviewed and additional clinical and laboratory observations relevant to the role of host defenses are summarized. Spontaneous regression of Burkitt's lymphoma provides compelling evidence for antitumor immunity. | 799,761 | [
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Serum gastrin levels in patients with renal failure on maintenance haemodialysis and after successful kidney transplantation. | Chronic renal failure in man is associated with a hypergastrinaemia which is not corrected by haemodialysis. Serum gastrin concentrations were measured in 66 patients on maintenance haemodialysis and in 27 patients after successful kidney transplantation. The basal gastrin levels distinguished 2 groups of patients on m... | 799,830 | [
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B and T cell surface markers on peripheral lymphocytes from diabetic patients. | A study of T and B cell surface markers was carried out on peripheral blood lymphocytes from diabetic patients, employing immunofluorescent staining for membrane Ig, and the E rosette test. According to the immunofluorescent studies the % of sIg bearing lymphocytes decreases with age; this trend is more evident in heal... | 799,831 | [
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[Properties of the contagious ecthyma virus used for vaccine production]. | Experiments were carried out to establish the effect of some antibiotics and merthiolate on the vaccinal Phylaxia strain of ecthyma contagiosa. Besides, followed up was the effect of these antibiotics on concomitant microflora that had multipled in the virus suspension. Trials were also made to titrate the vaccinal str... | 799,865 | [
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Effect of endotoxin on the peritoneal mast cells in mice. | Endotoxin administered intraperitoneally has been found to decrease the absolute and relative number of the peritoneal mast cells in mice. The number of peritoneal mast cells showed a dose-dependent biphasic response to endotoxin. Maximal and more consistent decrease in the peritoneal mast cell count was observed at ab... | 799,881 | [
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Functional differentiation of the FSH-synthesizing cells in the pars distalis of the fetal pituitary gland of the rat. | The onset of FSH synthesis in the embryonic pituitary gland of the rat was studied by a peroxidase-labelled antibody method. The first FSH-containing cells appeared on the 20th day of embryonic life. From that day onwards, FSH cells increased rapidly in number. It was found that in adult animals some pituitary cells re... | 799,882 | [
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Electron microscopic observations on the interaction of the myosin head subunit with actin in myofibrils. | Glycerol-extracted rabbit psoas muscle fibres were treated with a solution containing the head subunits of myosin. Interaction of the isolated myosin heads with actin filaments in situ was indicated by an increase in the density of the I-band and by an increased diameter of actin filaments alongside their whole length.... | 799,893 | [
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[Morphology of the juxtaglomerular apparatus of human allografted kidneys at the early periods after transplantation]. | Hyperplasia of the juxtaglomerula apparatus (epithelioid modified cells of the afferent arteriole, and Goormaghtigh cells) was observed at the early stages of existence of the human allografted kidney in the recipient's organism. These changes were accompanied by an increase of the juxtaglomerular index. In conjunction... | 799,937 | [
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Illusion and reality in R. D. Laing. | R. D. Laing never fully brings together his extraordinary empathy for schizophrenic individuals and his critical view of schizogenic families. In his writings, family and social interactions increasingly dissolve into subjective "scenarios," and ultimately, "inner space" becomes the source of the redeeming light. This ... | 799,969 | [
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Percutaneous absorption of betamethasone-17, 21-dipropionate and salicylic acid during the treatment of psoriasis and eczema. | The percutaneous absorption of betamethasone-17, 21-dipropionate and salicylic acid was studied after one and two weeks' treatment of psoriaris and eczema. The treated areas varied between 8 and 41 dm2. No change in the plasma cortisol levels was detectable by the routinely used laboratory method. The treatment gave no... | 799,983 | [
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Nefopam hydrochloride: new analgesic agent. | Two dose-levels of nefopam hydrochloride (i.e. 30 mg and 60 mg) were compared with two dose-levels of aspirin (i.e. 300 mg and 600 mg) and placebo in 125 male patients having pain associated with muscle disorders. Drugs were given as a single dose and pain intensity and side-effects monitored at thirty minutes and then... | 799,984 | [
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A clinical Trial of Tofranil in osteo-arthritis. | Animal experiments and uncontrolled clinical experience indicate that imipramine should relieve pain or enhance the effect of analgesics in osteoarthritis. A double-blind crossover trial using Tofranil 25 mg three times daily and matching placebo has, therefore, been designed and initiated. | 799,986 | [
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Butorphanol: a double-blind comparison with pentazocine in post-operative patients with moderate to severe pain. | A double-blind, randomized trial was conducted with 124 post-operative patients to compare the analgesic activity and possible side-effects of a new synthetic analgesic--butorphanol tartrate (1, 2, and 4 mg)--and pentazocine lactate (30 and 60 mg), adminstered intramuscularly. Butorphanol was determined to be 16 times ... | 799,996 | [
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Myocardial infarction without pain. A study of the sensory function of the upper limbs. | The sensory function of the upper limbs was examined in 18 subjects who had a myocardial infarction without a well-defined episode of chest pain. The cutaneous pain threshold was significantly higher than in normals. The ischaemia of the upper limbs induced patterns of sensations different from the normals, with onset ... | 800,252 | [
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Isolation of chloramphenicol-resistant variants from a human cell line. | Variant clones resistant to 40 microng/ml chloramphenicol were isolated from the human cell line VA2-B after treatment with either ethyl methanesulfonate or N-methyl-N'-nitro-N-nitrosoguanidine. Among 17 clones analyzed, one variant, CAP-23, was investigated in detail. CAP-23 cells in the presence of 40 or 100 microng/... | 800,292 | [
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0.1444128,
0.3766026,
0.477545,
0.07035456,
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-0.11... |
Immunocompetence, immunodeficiency and prognosis in cancer. | Immunocompetence and prognosis are related in solid tumors, malignant lymphomas, and acute leukemia. Among the parameters of immunocompetence vigorous delayed-type hypersensitivity responses to recall antigens or to primary immunization with Keyhole limpet hemocyanin, vigorous in vitro lymphocyte blastogenic responses ... | 800,324 | [
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[Degradation of intracellular proteins at different stages of growth of Saccharomyces cerevisiae]. | The rate of degradation of intracellular proteins at different growth stages of Saccharomyces cerevisiae yeast was determined. It has been demonstrated that the rate of degradation of intracellular proteins increases 2--3-fold at the late exponential phase. The increase was accompanied by corresponding changes in the a... | 800,346 | [
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0.3388479,
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... |
Hyperendemic subperiodic Bancroftian filariasis: a search for clinical and immunological correlates of microfilaraemia. | A study was carried out in the Kingdom of Tonga, an area of hyperendemic Bancroftian filariasis, to determine whether correlations could be made between microfilaraemia, as diagnosed by membrane filter concentration, and immunological (skin test, immunoglobulin levels) or clinical findings. There was no relationship be... | 800,355 | [
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A double-blind comparative trial of loxapine and trifluoperazine in acute and chronic schizophrenic patients. | A double-blind comparative trial of loxapine and trifluoperazine was carried out in 57 acute and chronic schizophrenic patients. In both groups of patients loxapine proved to be equivalent in its effects to trifluoperazine and there were suggestions it might be rather more effective in chronic patients. Side-effects we... | 800,384 | [
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Relationships among differentiated T-cell subpopulations. I. Dissociated development of tuberculin type hypersensitivity, Jones-Mote type hypersensitivity and activation of helper function. | Relationships among tuberculin type hypersensitivity, Jones-Mote type hypersensitivity and activation of helper T cells were studied in AKR mice by means of footpad reaction, migration inhibition test and antibody production against the trinitrophenyl group. (1) Immunization with SRBC in saline, Freund's incomplete adj... | 800,398 | [
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Limiting dilution analysis of helper T-cell function. II. An approach to the study of the function of single helper T cells. | Procedures have been described which are suitable for experiments utilizing a microculture system whereby one can easily study the function of single helper T cells. These are: (a) the elimination of the background anti-hapten response by preliminary anti-theta + guinea-pig complement complement treatment of the 'hapte... | 800,404 | [
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-... |
Methodological problems in the measurement of pain: a comparison between the verbal rating scale and the visual analogue scale. | The effect of analgesics on pathological pain in a double-blind, complete cross-over design was assessed by means of two rating scales, a verbal rating scale (VRS) and visual analogue scale (VAS). The VRS is widely used, but has several disadvantages as compared to the VAS. The results obtained by means of the VRS show... | 800,639 | [
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[Resistance to modification of dietary behavior]. | There exist certain pathological eating behaviors (they deviate from the usual eating pattern in a given environment; ex.: hyperphagia, alcoholism, bulimia, nibbling sweets, etc.): there also exist certain pathogenic, though not pathological, eating behaviors (a "normal" behavior may induce an affection in given subjec... | 800,713 | [
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[Culinary art and social change: some remarks]. | The development in France, long a rural country, of a new type of civilization characterized by industrialization, urbanisation and their corollaries threatens (in a real or imaginary way) both the quality of food (standardization, agricultural, industrialization and new toxicological and pollution problems) and the so... | 800,719 | [
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[Calculation of the volume of the grafted kidney. Value of this measurement by echotomography in renal transplantation]. | From a necropsy series of 14 kidneys, it is very easy to prove, that there is a quite good correlation between the theorical calculated volume of the kidney and its real volume. It is possible to compare the kidney to an ovoid, and to calculate its volume, knowing the 3 dimensions which are its length, its width, its d... | 800,727 | [
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0.3277768,
0.1228701,
0.2741625,
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[Interaction in vitro between polymorphonuclear leukocytes and subcellular fractions of Streptococcus pyogenes]. | The effects of cellular subfractions of S. pyogenes on phagocytosis from neutrophils were studied. Cell-walls and membranes were found to stimulate the phagocytosis at low concentrations: at immediately higher doses they show to have a citotoxic effect. | 800,771 | [
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Hypothalamo-pituitary-adrenal function in Parkinsonian patients treated with melatonin. | The pineal principle, melatonin, was administered to 4 Parkinsonian patients. Hypothalam0-pituitary-adrenal function tests were performed before and after 4 weeks of treatment. At a maximum dosage of 1 g daily no impairment of H-P-A function was detected. | 800,974 | [
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Comparison of chemical and immunological characteristics of some commercially obtainable conjugates. | A method is suggested for the chemical and immunological characterization of commercially obtainable conjugates. 19 antihuman IgG; IgA; IgM and beta1A-beta1C conjugates of various origine were compared by means of the method. The most surprising characteristics of the samples were the great differences in that quality.... | 801,134 | [
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Galton and the birth of differential psychology and eugenics: social, political, and economic forces. | The social, political, and economic forces operative in nineteenth-century Britain are briefly described. This permits tracing the birth of both the scientific study of individual differences and the field of eugenics to the infrastructure of society at that time. The distinction is made between the normative doctrine ... | 801,144 | [
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IgA nephropathy in children. | Three children presented with proteinuria, microscopic hematuria, episodic gross hematuria and normal renal function. Renal histology consisted predominantly of mesangial IgA deposition. The above clinical and biopsy findings are consistent with a diagnosis of IgA nephropathy. To date, these 3 children have maintained ... | 801,208 | [
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Bladder defense mechanism. | In order for micro-organisms to infect the urinary tract they must adhere to the vesical mucosa so that they remain after voiding. Experiments in our laboratory demonstrated that the bladder has a self-protective mechanism capable of preventing bacterial adherence to the surface. Histochemical staining demonstrated tha... | 801,214 | [
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[The vascular patterns in choroïd tela of the fourth ventricle in man (author's transl)]. | The human inferior choroid tela is vascularized by the posterior inferior cerebellar arteries and the anterior inferior cerebellar arteries. These arteries give off small choroid branches which supply the velate and choroid capillary networks. The latter drain downwards, into the posterior bulbar veins system, or upwar... | 801,319 | [
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Arterial vasculature of cervical skin flaps. | Old age and preoperative radiotherapy both decrease the blood supply to neck skin. It is therefore necessary to know how the skin flaps which are raised in neck surgery, receive their blood supply. By using silicone rubber injections we have studied the blood supply to the cervical skin in human cadavers before and aft... | 801,346 | [
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... |
Biogenesis of aroma constituents of fruits and vegetables. | The aroma of fruits and vegetables may be considered to originate from the basic nutrients such as carbohydrates, proteins, and fats, as well as vitamins and minerals. These nutrients, in turn, are produced by photosynthetic and related metabolic activities occurring in the plant. Current interests in aroma of fruits a... | 801,351 | [
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Biology of the twinning phenomenon: embryogenesis and teratogenesis. | The twinning phenomenon has always interested the great public, the artists, and naturally the scientists. Isidore Geoffroy St. Hilaire has established a classification still now valid. This classification considers the different types of double monsters which are found in nature in all classes of vertebrates, includin... | 801,414 | [
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[Influence of fatty-acid and glucose content of the perfusate on the energy metabolism of the preserved canine kidney]. | Thirty-seven canine kidneys were preserved by hypothermic low flow perfusion for 24-120 h with solution I containing albumin, free fatty acids, and glucose, or with solution II containing Haemaccel without free fatty acids or glucose. Following 48 h preservation the renal ATP and SAN content was identical in both group... | 801,555 | [
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0.1064656,
0.2395473,
0.02340015,
-0.37... |
[Demonstration of blocking factors in permanently surviving rat-kidney allograft recipients after short postoperative treatment with alloantiserums]. | GvHR tests were performed on spleen cells of 9 recipients surviving rat renal allografts for more than 120 days. The recipients had undergone a short term ALS-treatment. The GvHR tests showed normal cell-mediated immunity. After splenectomy and again 18 days later LBNF1 skin was grafted to the renal recipients. After a... | 801,562 | [
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Ionic basis of excitation mechanism in cardiac muscle. | Cardiac electrical activity is due to passive ionic permeabilities and, partially, to nonneutral (electrogenic) active transport, but extracellular accumulation or depletion of potassium is also of importance. The rapid sodium current responsible for the spike of the action potential and the slow calcium or calcium and... | 801,571 | [
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... |
Buprenorphine as postoperative analgesic. | In 150 patients buprenorphine was given as postoperative analgesic in a dose of 4 microgram/kg. Pain suppression was judged very good (71%), fairly good (24%) and insufficient (5%). Analgesic activity lasted at least 325 +/- 15 min. Side effects were few. | 801,582 | [
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Contact allergy: predictive testing in man. | Predictive tests are of value in forecasting the response of a population to a sensitizer; diagnostic testing is used to determine what substances may actually be producing dermatologic problems. Skin sensitization predictive and diagnostic data for the eleven most frequently encountered skin sensitizers in Western Eur... | 801,606 | [
0.116696,
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[New findings concerning the coronaroactive proteins of the hypothalamus]. | Our previous studies have shown that the two coronarodilatatory hypothalamic proteins isolated by us are not only carriers for neurohormones "K" and "C" but also procursors of coronarodilatory substances. In the present study we have looked at some physico-chemical properties of these proteins through isoelectric focus... | 801,692 | [
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0.2043637,
0.06911393,
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-0.2534296,
... |
Glomerulonephritis with mesangial deposits of IgA unassociated with systemic disease. | Typical features of IgA-associated nephritis were found in renal biopsies from 16 of 355 consecutive patients. Generalized segmental mesangial proliferation was noted in biopsies from most patients, and dense deposits were detected by electron microscopy in mesangial regions of approximately 50% of biopsies. Immunofluo... | 801,796 | [
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[Experiences with the glyoxylic-acid fluorescence method for the demonstration of biogenic amines in cuticle preparations, cryostat- and simple frozen sections]. | 1. Our studies aimed at methodical simplification to make available the glyoxylic acid-fluorescence method to everybody. We succeeded in receiving adequate results in the case of whole mounts, cryostat- and simple frozen sections. 2. Making ready the slide preparations may be divided into 5 steps:--incubation of fresh ... | 801,849 | [
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0.4656443,
-0.1550008,... |
[Methods and problems of spermatogonia counts in histological section preparations]. | The number of spermatogonia of the testicles is an important criterion for the assessment of the probable fertility prognosis. The determination of the mean content of spermatogonia per cross section of one tubulus seminiferus is considered as a standardized procedure in clinical practice. Counts of spermatogonia in 4 ... | 801,850 | [
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[Determination of statistical error using the hit method]. | Referring to a histological example, an explanation is given which parameters of the hit procedure have an influence upon the magnitude of the random measuring errors. The dispersion of the measuring values decreases as the number of test points increases. Moreover, if the number of test points is equal, the dispersion... | 801,851 | [
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Comparison of the microhemagglutination assay for antibodies to Treponema pallidum and the automated fluorescent treponemal antibody-absorption test. | The qualitative microhemagglutination assay for detection of antibodies to Treponema pallidum and the automated fluorescent treponemal antibody-absorption tests were directly compared as confirmatory tests for syphilis. They were compared on 2,790 specimens from patients of New York City Social Hygiene Clinics. Overall... | 802,487 | [
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Primary structure of tRNA-Lys of E. coli B. | The primary structure of tRNALys of E. coli was determined by use of [32P]-tRNA. The sequence is pGGGUCGUUAGCUCAGDDGGDAGAGCAGUUGACUmam5-s2-UUU-t6AApsiCAAUUGm7GXCGCAGGTpsiCGAAUCCUGCACGACCCACCA. No s4-U was detected in position 8. No other lysine tRNA was detected but the existence of another species has not been ruled o... | 802,509 | [
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Electrical and dynamic responses of the human hyperkinetic heart to sympathetic stimuli. | 1. The elevated beta-receptor responsiveness to adrenergic stimuli makes subjects with the primary hyperkinetic cardiac syndrome ideal for studying the electrical and dynamic responses of the heart to sympathetic activation. 2. In twelve men presenting with the syndrome, the effects of mental arithmetic and painful (co... | 802,642 | [
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... |
Chemistry and physiology of parathyroid hormone. | Many recent studies, only a few of which are reviewed here (see Habener & Potts, 1976, for a detailed summary) have led to considerable clarification concerning critical features of the chemistry, biosynthesis, secretion and mode of action of parathyroid hormone. Certain of the confusion recently experienced in mea... | 802,686 | [
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[Effect of oligoribonucleotides specifically bound by E. coli RNA-polymerase on DNA-dependent RNA synthesis]. | It was shown previously that E. coli RNA-polymerase (EC 2.7.7.6) selectively binds certain fractions of penta- or hexaribonucleotides random mixtures (Knorre V. L., Vasilenko S. V., Salganik R. I., FEBS Lett., 30, 229, 1973). The data obtained demonstrate that such oligoribonucleotides compete with DNA for the RNA poly... | 802,772 | [
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0.0... |
[In relation to the terms infection and infestation]. | A study on the terms "infection" and "infestation" is made according to the definitions found in different works. Confusions emerging from their use are commented. The solution of the problem could be achieved by the use of definitions which determine with precision the expresive content of both terms. | 802,801 | [
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Congenital renal arteriovenous fistula: case report, review of Japanese literature and description of non-radical treatment. | A case of congenital arteriovenous fistula diagnosed by measuring the oxygen saturation difference of renal veins at the time of selective renal angiographic examination and a review of 38 relevant Japanese cases are reported. The English as well as the Japanese literature was reviewed. Treatment has consisted of parti... | 802,859 | [
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0.2... |
Clinical management of non-testicular intrascrotal tumors. | Our 10-year experience with non-testicular intrascrotal tumors has been combined with an extensive survey of the literature. The over-all incidence of malignancy affecting intrascrotal structures is high: 1) 25 per cent of epididymal neoplasms are malignant, 2) excluding cord lipomas, 56 per cent of cord tumors are mal... | 802,862 | [
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0.2793956,
0.04114218,
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... |
[Urography in the diagnosis of chronic renal insufficiency. I. Urographic study]. | Reviewing urography in chronic renal failure, questions of patient preparation, the choice of a contrast medium and its dose, radiological technique, complications, and limitations and contraindications of the examination are discussed. | 802,905 | [
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0.06974... |
[Radiotherapy of lymphomas. Clinical classification, radiotherapy planning and indications]. | The staging of Hodgkin's disease and non-Hodgkin lymphomas is discussed with reference to the treatment plan indicated for each stage and the problems associated with radiotherapy. | 802,921 | [
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0.001915869,
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0.1538249,
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Leucocyte migration test in patients after corneal transplantation. | Twenty-four patients with corneal homografts were repeatedly evaluated by the leucocyte migration test using pooled human corneal extract 0.2 mg/ml as antigen. All patients were treated with small doses of local or systemic steroids. If cloudiness of the graft developed, the doses were increased up to 40 mg methylpredn... | 802,929 | [
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0.263639,
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0.2380376,
0.009... |
Investigation by immunofluorescence of arterial lesions in rabbits on two different lipid supplements and treated with pyridinol carbamate. | Rabbits maintained on a pellet diet supplemented with cholesterol, or on a semi-synthetic diet containing beef fat but no added cholesterol, have been studied in relation to their development of hyperlipidaemia and of lipid-filled arterial lesions. The influence of pyridinol carbamate on animals on both diets was also ... | 802,937 | [
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0.6768857,
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0.6280594,
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0.2315... |
Speech changes in Parkinson's disease during treatment with L-dopa. | The speech of 17 Parkinsonian patients was evaluated before and after the administration of L-DOPA therapy. A significant difference was demonstrated after treatment for voice quality, articulation, and pitch variation, but not for rate of speech. Amount of speech improvement correlated significantly with amount of phy... | 802,977 | [
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0.03110587,
-0.222... |
Basal pitch and frequency level variation in male and female children: a preliminary investigation. | Measurements of basal pitch and frequency level were determined for fifteen normal speaking school-aged children on each of two consecutive days during three time periods each day. The results indicated that as a group, the male children's basal pitch and frequency levels did not change significantly within and across ... | 802,980 | [
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... |
Attributes of loudness, pitch and rate among male children. | Ratings, by trained judges, of vocal loudness level, pitch level and rate of speaking for a nonpathological sample population of male children were studied relative to subjective ratings of vocal merit. Averaged physical measurements for loudness level, pitch level and rate of speaking determined points of reference an... | 802,988 | [
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Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamin and vitamin B6. | Absorption of folates, thiamin, vitamin B6, pantothenate and riboflavin from a natural food source--yeast--and their respective synthetic forms was studied in 37 patients with liver disease due to alcoholism, and 12 healthy, nonalcoholic subjects. All alcoholics absorbed riboflavin and pantothenate but had a significan... | 802,999 | [
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-... |
Stimulation of albumin synthesis by amino acids following partial hepatectomy in the rat. | Albumin synthesis was measured, in vivo, in rats 16 hours after partial hepatectomy or after sham operation. When albumin synthesis was expressed in terms of whole body weight, partially hepatectomized rats synthesized significantly less than sham-operated rats. However, when albumin synthesis was expressed as a functi... | 803,003 | [
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Food intake, its relationship to body weight and age, and its apparent nutritional adequacy in New Guinean children. | Previous nutritional investigations in New Guinea have shown low intakes of protein and of energy yet the nutritional status of children and their ability to thrive have been regarded as better than could be expected. To investigate this apparent paradox, the dietary intakes of 482 New Guinean children, aged 1-18 years... | 803,007 | [
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Polycystic ovarian disease, maturation arrest of spermiogenesis, and Klinefelter's syndrome in siblings of a family with familial hirsutism. | A family with hirsutism in five generations in which polycystic or bilaterally enlarged ovaries were documented in three different sibships of two generations is described. Two brothers of one of the women with polycystic ovaries had a low or low-normal plasma follicle-stimulating hormone level and one of these had oli... | 803,038 | [
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... |
Anatomical comparison between acupuncture and nerve block. | Although there are numerous acupuncture points, it is our purpose to point out the similarity in the location of some of these and the location of anatomic sites commonly used for local and regional anesthesia. We believe that acupuncture can be used in conjunction with local anesthesia, nerve-block, or alone, in the c... | 803,045 | [
0.1378883,
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Metabolic arrest of the ischemic heart. | Procaine, hypocalcemia, magnesium, fluoride, adrenochrome, and tetrodotoxin have been used to induce metabolic arrest of the heart and increase its tolerance to ischemia. Prolonged periods of ischemic cardiac arrest without measurable deterioration of cardiac function are possible. The application of these techniques i... | 803,062 | [
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... |
Cochlear nerve degeneration coincident with adrenocerebroleukodystrophy. | A 19-month-old boy had adrenocerebroleukodystrophy and unusually severe cochlear nerve degeneration and demyelination, a condition in advance of that expected from known disease entities. We report the only known temporal bone study in adrenocerebroleukodystrophy. | 803,065 | [
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0.07675567... |
Therapy of unilateral pulmonary insufficiency with a double lumen endotracheal tube. | Successful therapy of unilateral acute lung disease has been infrequent. The marked compliance difference that exists between the acutely diseased and normal lung may make conventional respiratory therapy ineffective in treating the diseased lung. Vigorous attempts at reexpansion of the involved lung including bronchos... | 803,089 | [
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The effect of chemotherapy on the kinetics and proliferative capacity of normal and tumorous tissues in vivo. | The proliferative state of a given tissue is a major determinant of its sensitivity to both phase-specific and cycle-specific chemotherapeutic agents. To study the extent of injury induced by antitumor agents to normal and tumorous tissues, a technique for following DNA synthesis as reflected in the incorporation of tr... | 803,102 | [
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Interactions of mothers and nurses with premature infants. | The initial attachment of three mothers to three premature infants weighing less than 1500 g was assessed by observation of the mother's behaviour during visits to her child in the hospital nursery. Interactions of mothers and infants were compared with those of nurses and infants. Premature infants, during a stay in h... | 803,124 | [
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Sudden unexpected death in children with congenital heart disease. | Of 18,000 children with organic heart disease evaluated at The Hospital for Sick Children, Toronto between 1940 and 1971, 33 died suddenly and unexpectedly between 1 and 21 years of age. Nine had discrete obstruction of the left ventricular outflow tract and five had muscular narrowing of the left ventricular outflow t... | 803,125 | [
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-0.312988,
0.439... |
Parental mislabeling of female genitals as a determinant of penis envy and learning inhibitions in women. | A survey of sex education literature confirms parents' self-reports regarding sex information imparted to their children. With relatively few exceptions, young children (and even teenagers) are taught that "boys have a penis and girls have a vagina," without further linguistic distinctions made regarding the sensitive ... | 803,146 | [
0.001415506,
0.4633181,
0.2024146,
-0.3262915,
0.641507,
-0.2580016,
-0.02970226,
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0.1633969,
0.4649325,
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-0.2474032,
0.01232577,
-0.3717908,
0.02352091,
-0.3232351,
-0.086015,
0.4003534,
0.006926035,
-0.2660885... |
Prevention of intraoperative myocardial injury by pretreatment with pharmacological agents. | Pharmacological agents administered prior to the institution of myocardial anoxia or ischemia may protect the myocardium by preventing ATP depletion, structural damage to cell membranes and organelles, and postanoxic disturbances in coronary microcirculation. Propranolol, dipyridamole, nitroglycerin, and mannitol all h... | 803,168 | [
-0.3611571,
0.1469655,
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0.1643109,
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0.3332676,
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0.05421319,
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0.3868317,
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-0.08195895,
-0.1038868,
-0.02785819,
0.284052,
-0.09692639,
0.0190781... |
Biochemical changes of ischemia. | Normothermic ischemic arrest by aortic cross-clamping, a widely used clinical technique, is associated with metabolic changes in the myocardium that are incompletely understood. The effects of aortic cross-clamping on glycolytic pathways as well as associated morphological changes are discussed. Emphasis is placed on t... | 803,171 | [
-0.2053179,
0.156572,
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0.02370926,
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0.1717717,
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0.03064879,
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0.3472061,
0.1654488,
0.3639087,
-0.104346,
0.14... |
'There, but for the grace of God...'. | The number of deaths reported as associated with anaesthesia in England and Wales has fallen dramatically during the past 20 years. But the problem of cardiac arrest occurring while the patient is under the care of the anaesthetist, though small, remains a serious one because few such patients survive, even with seriou... | 803,181 | [
-0.1551774,
0.1549654,
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0.06085129,
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0.1501169,
0.03904273,
0.4481514,
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0.2119552,
0.05241996,
0.06413562,
0.06454369,
0.1047926,
-0.01804298... |
Brain metabolism in the critically ill. | A large number of clinical conditions are associated with a transient or permanent disturbance of brain function. Common to all of them is that, in some way, brain metabolism is changed from the normal. These changes cover a vast spectrum, ranging from the subtle alterations of metabolism encountered in mental disease ... | 803,179 | [
-0.1905114,
-0.078686,
0.1495264,
-0.03198336,
0.07667755,
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0.006241743,
0.05289812,
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0.2325751,
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-0.4324588,
0.09854765,
0.03182057,
0.3245224,
-0.07491149,
0.2262601,
-0.1530... |
A hypothetical case of gastrointestinal bleeding: incorporating a management self-test. | In this case study of upper gastrointestinal bleeding, a problem-solving question-and-answer format is used and is accompained by referenced discussion. The clinical area covered is one in which endoscopic and angiographic tools are available for diagnosis and tamponading devices and angiographic perfusion techniques e... | 803,239 | [
-0.3783827,
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-0.1930878,
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0.09892291,
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0.3976832,
0.4782585,
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0.1541736,
-0.2692358,
-0.09690955,
-0.4057805,
-0.08280095,
0.2951756,
0.05121292,
-0.11616... |
Effect of polychlorinated biphenyl formulations on the growth of estuarine bacteria. | Polychlorinated biphenyl formulations inhibited the growth of certain estuarine bacteria. The sensitive strains, although exhibiting some similar physiological characteristics, contained both gram-positive and gram-negative bacteria. | 803,286 | [
0.08925775,
-0.1302248,
0.06606934,
0.01506474,
-0.2842642,
0.04456652,
-0.4401011,
0.0167207,
0.04875768,
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0.0275354,
0.02656757,
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0.5636829,
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0.3557492,
0.04270733,
0.1621192,
0.2116659,
0.2959273,
-0.02188605,
... |
The Health Maintenance Organization Act of 1973 (P.L. 93-222) and prepaid group practice plans. | Passage of the 1973 Health Maintenance Organization Act (P.L. 93-222) represents a significant effort by the Federal government to experiment with organizational change in the structure of the health care delivery system. The history of the bill is briefly reviewed. The most important sections of the bill are analyzed ... | 803,289 | [
-0.2052712,
0.13183,
-0.1463645,
0.05708988,
0.2712406,
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0.09423986,
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0.02385977,
0.1029782,
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0.07675383,
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-0.1253182,
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0.2263554,
0.2421285,
-0.2384917,
... |
Community Mental Health--new approaches for rural areas using psychiatric social workers. | In 1970, a private medical group practice serving a large rural area introduced pyschiatric social workers in an integrated clinic to provide accessible mental health services to all economic levels in the community. Public acceptance confirmed the demand. The rapidity with which other community mental health needs wer... | 803,292 | [
-0.2834333,
0.01336049,
0.09906346,
-0.2059451,
-0.006801504,
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-0.1108732,
0.1495338,
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0.06771561,
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-0.4258554,
0.04805643,
0.04921588,
-0.1359684,
-0.1810776,
0.3968488,
-0.05... |
The Dyggve-Melchior-Clausen syndrome. | The Dyggve-Melchior-Clausen syndrome is an inherited disorder of skeletal development characterized by short-trunked dwarfism, mental retardation, and a distinctive pattern of bone changes. The radiographic features seen in the 15 patients described in this report include platyspondyly with notched end plates of the ve... | 803,318 | [
0.1150857,
0.004888504,
0.2661344,
-0.3281707,
0.1163925,
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-0.53482,
0.09822917,
-0.02709031,
0.2682597,
0.1742059,
0.1711444,
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0.004389209,
0.2356301,
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-0.04973946,
0.03372649,
-0.1661321,
0.5549225,
0.05249,
-0.2821331,
0.0... |
Infectious bovine keratoconjunctivitis II. Antibodies in lacrimal secretions of cattle naturally or experimentally infected with Moraxella bovis. | Preinfection, acute and convalescent phase lacrimal secretions from 20 cattle that had mild to severe keratoconjunctivitis (associated with natural or experimental Moraxella bovis infection) were tested for specific antibody to M. bovis as well as for immunoglobulins, particulary of the A class. The convalescent phase ... | 803,398 | [
-0.1689786,
-0.5122237,
-0.3820588,
-0.03226377,
0.06822874,
-0.09017888,
-0.367611,
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0.2267771,
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0.06113909,
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-0.2362821,
0.05969559,
-0.05034601,
0.01064867,
0.1662141,
-0.1701347,
0.02... |
Intestinal lymph formation and fat absorption: stimulation by acute ethanol administration and inhibition by chronic ethanol administration and inhibition by chronic ethanol feeding. | The acute administration of ethanol, either in lipid emulsions administered intraduodenally or in liquid diets given by gastric tube, increased the flow of intestinal lymph and the output of proteins and dietary lipids into the lymph, mainly in the 1st hr after administration. During this time, the intraduodenal admini... | 803,464 | [
-0.06521408,
-0.1551631,
-0.3952461,
0.08828383,
0.1406983,
-0.5167288,
0.08718366,
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0.1373115,
0.01034289,
-0.4069961,
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0.08813392,
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-0.5302789,
-0.3283891,
-0.3900311,
0.04294996,
-0.03323707,
0.1857589,
0.05700... |
Identification of measles virus-specific hemolysis-inihibiting antibodies separate from hemagglutination-inhibiting antibodies. | The occurrence of antibodies giving hemolysis inhibition (HLI) but not hemagglutination inhibition (HI) was examined in human convalescent and rabbit hyperimmune sera. HI antibodies, which through their interaction with hemagglutinin components display HLI activity, were removed by absorption with Tween 80-ether (TE)-t... | 803,467 | [
-0.3337186,
0.148109,
0.04824645,
-0.04112308,
0.1343495,
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0.140546,
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0.2243896,
0.3045177,
0.1065472,
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0.03880428,
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0.2011376,
0.3109566,
0.1542645,
-0.2065477,
-0... |
Detection and serological identification of adeno-associated virus in avian adenovirus stocks. | Eleven avian adenovirus strains were tested for the presence of avian adeno-associated viruses (AAAV). Six strains contained AAAV. Electron microscopy using rabbit anti-AAAV serum was useful in detecting the satellite virus. The AAAV previously isolated from guail bronchitis virus was related to each of the six new iso... | 803,468 | [
-0.01362177,
0.3104892,
0.003647224,
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0.2515681,
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0.0478285,
0.02905579,
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0.05026309,
0.2722378,
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0.003206143,
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0.2300611,
-0.06829115,
0.06965933,
0.01664734,
0.01301958,
-0.208353... |
Production and possible function of serine protease during sporulation of Bacillus subtilis. | The production of extracellular protease during sporulation in Bacillus subtilis 168 was investigated. Two proteases are produced, an alkaline serine protease and a neutral metalloprotease. In vivo inhibition of the serine protease with phenylmethylsulfonylfluoride indicated that the metalloprotease was degraded by the... | 803,477 | [
-0.2649759,
-0.2070699,
-0.2804056,
0.1987042,
0.0745016,
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-0.03752401,
0.1004364,
0.04959471,
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0.07273686,
0.3552586,
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0.0683723,
0.1446837,
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-0.2326255,
0.2197164,
0.5828341,
0.1796756,
-0.2238546,
... |
Bacillus subtilis N-acetylmuramic acid L-alanine amidase. | The N-acetymuramic acid L-alanine amidase from Bacillus subtilis (ATCC 6051) has been purified to homogeneity. It is a monomeric protein of molecular weight 50,000. The enzyme has a high affinity for homologous cell walls and once attached to a cell wall will hydrolyze the wall completely before initiating the hydrolys... | 803,507 | [
-0.1282873,
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0.1754759,
0.2007214,
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0.0249272,
0.09548026,
0.04480579,
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-0.354562,
-0.09084193,
0.0194112,
0.06568918,
0.6713365,
0.002226361,
-0.1276868,
... |
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