title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Lamination and differential distribution of thalamic afferents within the sensory-motor cortex of the squirrel monkey. | The structure of the first somatic sensory area (areas 3, 1 and 2), of the motor area (area 4) and the intervening transitional field (area 3a) is described in the squirrel monkey (Saimiri sciureus) using Nissl, Bodian, Weil and Golgi preparations. The laminar arrangement of both cells and axons is briefly described an... | 803,517 | [
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The characterization of human anti-IgG autoantibodies by liquid isoelectric focussing. | A series of human anti-IgG autoantibodies (AGA) have been analyzed by liquid isoelectric focusing in order to a) determine their isoelectric points (pI) and b) assess their heterogeneity. The 13 AGA examined include five IgM, five IgA, and three three IgG AGA. All demonstrate a single major peak indicative of restricte... | 803,526 | [
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Hemodialysis leukopenia and polymorph random mobility-a possible correlation. | In vitro studies of polymorphs exposed to cellulose and polysulfone membranes showed severe impairment in randommobility with the cellulose membrane. In vivo studies with the two membranes showed that profound leukopenia occurred only when cellulose membrane was used. It is suggested that random mobility may have impor... | 803,539 | [
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Isolation of lipopolysaccharide from the walls of Micropolyspora faeni: chemical composition and serological reactivity. | Extraction of mycelium or walls of Micropolyspora faeni with cold or hot aqueous phenol yielded a lipopolysaccharide consisting of lipid A, phosphate, galactose, arabinose, glucose, glucosamine, and a dideoxy sugar. Extraction with trichloroacetic acid (TCA) yielded an incomplete molecule lacking lipid A. Part of an O-... | 803,548 | [
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The inheritance of penicillin titre in wild-type isolates of Aspergillus nidulans. | In a sample of 52 wild-type isolates of Aspergillus nidulans, penicillin titre ranged from 0-0 to 14-4 units/ml. These differences in titre were under genetic control. Most of the variation between isolates was attributable to differences between heterokaryon-compatibility groups although significant differences were a... | 803,549 | [
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Studies on the vitamin nutrition of the cellular slime mould Dictyostelium discoideum. | Vitamin auxotrophs of Escherichia coli grown in the presence or absence of the corresponding vitamin were used as substrates for the growth of Dictyostelium discoideum strain Ax-2 in order to investigate some of the growth-factor requirements of this cellular slime mould. Compared with the growth yields observed on vit... | 803,550 | [
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Distribution of 67-Ga following intravenous administration: effects of disodium edetate therapy. | Following intravenous administration of 67Ga-citrate to normal and abscessed rats, the colon content of 67Ga decreased with increasing oral doses of Na2EDTA. The effects observed, however, were not thought to be of potential clinical value. | 803,557 | [
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Effects of administration of estrogen or diphenylhydantoin on the kinetics of diphenylhydantoin in man. | The rate of disappearance of 131I-diphenylhydantoin (131I-DPH) from plasma and its hepatic uptake were studied during a control period and after estrogen administration in ten normal human subjects. Four subjects were given DPH and were studied in the same fashion as the estrogen-treated group. After intravenous inject... | 803,558 | [
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In situ lysis of phi29- and SPO1-infected Bacillus subtilis. | An improved method of in situ lysis of bacteriophage-infected Bacillus subtilis was developed and used to study phi29 and SPO1 phage structures produced by individual cells. | 803,567 | [
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[The effect of vaccination status on the clinical form and outcome of the disease in smallpox patients (author's transl)]. | During the smallpox epidemic in Yugoslavia in 1972, which involved 175 persons altogether, with 35 (=20 per cent) fatal cases, a number of very important aspects emerged, especially at Kosowo (124 cases0: smallpox vaccination gives almost complete protection for 5 years and a relative immunity for about 10 years. Vacci... | 803,614 | [
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[Use of ketamine in cardiac surgery. A preliminary report]. | The phencyclidine derivative, ketamine hydrochloride, combines cardiovascular stimulating effects with antiarrhythmic properties and, therefore, the drug has been shown to be a highly suitable anesthetic for coronary artery surgery. This intravenously and intramuscularly administered "dissociative" anesthetic selective... | 803,635 | [
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[Value of sequential scintrigraphy and clearance determination following normo- and hypothermic renal ischemia]. | Using quantitative sequential camera scintigraphy and simultaneous separated clearance determinations with 131-I-Hippuran and 169-Yb-EDTA renal function was measured applying a new surgical method which permits in-situ kidney perfusion and cooling in animals and patients. While mongrel dogs of 15 kg average weight (con... | 803,677 | [
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Total body potassium and serum electrolyte concentrations in protein energy malnutrition. | The total body potassium (TBK) and serum electrolyte concentrations of malnourished children in Cape Town are similar to those in Jamaica. The TBK is almost always low and hyponatraemia is common, but there was no relationship between the TBK and serum Na and K concentrations. These abnormalities, particularly a very l... | 803,719 | [
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Recent advances and controversies in the management of Hodgkin's disease. | Sifting the preceding factors, which may weigh for or against routine laparotomy and splenectomy as a staging procedure in Hodgkin's disease, we advocate that one be sure the diagnosis and histologic classification are confirmed by an experienced hematologic pathologist, that complete clinical studies for clinical stag... | 803,722 | [
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Routine screening of donor plasma suitable for the preparation of antitetanus immunoglobulin. | A radial immunodiffusion assay for serum antitetanus antibody has been in routine use in this laboratory for 12 months. It has proved simple and reliable for the screening of normal blood donors. Earlier preliminary observations - that (a) 4.4% East Anglian donors have antibody levels of 5 IU/ml or more and (b) 29% of ... | 803,742 | [
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The exchange of thyroxine between plasma and liver: the role of free thyroxine. | An investigation has been made into the exchange of thyroxine between human plasma and the perfused rat liver. A stop-flow method was used to hold plasma within the liver sinusoids for periods up to 20 min. At 20 degrees C it was found that thyroxine present in the sinusoids transferred to the liver at a rate of 5-6%/m... | 803,749 | [
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The effects of halothane and enflurane on rat brain synaptosomal sodium-potassium-activated adenosine triphosphatase. | Synaptosomes, or nerve-ending particles, were isolated from the cerebral cortices of young rats by homogenization, differential centrifugation, and density-gradient centrifugation. The sodium-potassium-activated adenosine triphosphatase enzyme system [(Na+ plus K+)-ATPase] of these particles is believed to represent in... | 803,797 | [
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Influence of modified atmosphere storage on aflatoxin production in high moisture corn. | Samples of freshly harvested corn and remoistened corn were inoculated with Asphergillus flavus and stored for 4 weeks at about 27 C in air and three modified atmospheres. Aflatoxins and fat acidity were determined weekly. Corn stored in the modified atmospheres did not accumulate over 15 mug of total aflatoxins per ... | 803,817 | [
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Actinomycetales from corn. | Mesophilic Actinomycetales were isolated from whole corn, brewers grits, and break flour received from three different mills. In addition, strains were isolated from high-moisture (27 per cent) field corn; high-moisture, silo-stored corn (untreated); and high-moisture corn treated with ammonia, ammonium isobutyrate, o... | 803,819 | [
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Metabolic studies in rats of (75-Se)selenomethionine and of 75-Se incorporated in vivo into rabbit kidney. | 1. [75-Se]selenomethionine was administered to four rabbits and after 4 d their kidneys were removed and homogenized. The long-term fate in rats of an oral dose of this kidney homogenate (RK-75-Se) was compared with that of an oral dose of ]75-Se]selenomethionine mixed with unlabelled rabbit kidney homogenate. 2. Urina... | 803,837 | [
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Preliminary observations on the protective action of a cytoplasmic immunogen of Neisseria gonorrhoeae. | A non-toxic protein, termed beta(-t), consisting of lysine, aspartic acid, threonine, serine, glutamic acid, glycine, and alanine (1.2:1.3:1.3:3:2.2:7:1) was isolated, by the polyacrylamide gel electrophoresis, from an isoelectric toxic proteinaceous fraction beta(+1) of the type 1 cytoplasm of N. gonorrhoeae. The beta... | 803,861 | [
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Melanogenesis in human melanomas. | A number of biochemical aspects of melanogenesis were studied in 15 variously melanized human melanomas. The tryosinase activity was correlated with the degree of melanoma varied from 3,667 to 46,183 tryosinase units, in partially melanotic melanoma it varied from 14 to 75 tryrosinase units. The subcellular distributio... | 803,870 | [
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GammaG-globulin production and light-chain metabolism in patients with metastatic cancer. | GammaG-Globulin and excess light-chain metabolism were studied in eight subjects with progressive metastatic malignant disease by determining the plasma radioactivity curves following the administration of appropriately labeled substances. In addition to the plasma die-away curves, which required about 3 weeks for full... | 803,873 | [
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Studies on gonococcus infection. VII. In vitro killing of gonococci by human leukocytes. | The comparative killing of pilated and nonpilated forms of Neisseria gonorrhoeae by human peripheral blood leukocytes was studied in vitro. Some nonpilated gonococci (T2) were killed to a lesser extent than were pilated, T2 organisms, which were killed less readily than another nonpilated (T4*) form of gonococcus. Thus... | 803,924 | [
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Immunological studies of an antigen common to many gram-negative bacteria with special reference to E. coli. Characterization and biological significance. | A number of different bacterial strains were analyzed for the presence of common antigens using immunodiffusion techniques. Most of the studied E. coli strains had many common antigens. Especially one antigen was found in all investigated E. coli as well as Proteus and Pseudomonas strains and antibodies to this antigen... | 803,931 | [
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The partial purification and properties of pig brain glycogen synthase. | Both the I (independent of glucose 6-phosphate) and D (dependent on glucose 6-phosphate) forms of glycogen synthase (UDP-glucose:glycogen alpha-4-glucosyltransferase EG 2.4.1.11) have been partially purified from pig brain and the kinetic constants of the enzymes have been examined. The Km for UDP-glucose for the I for... | 803,970 | [
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Bence Jones proteins and light chains of immunoglobulins. XI. A transient Bence Jones-related protein associated with corticosteroid therapy. | Urine specimens from patients with multiple myeloma and Bence Jones proteinuria frequently contain low molecular weight proteins which correspond either to the amino-terminal, variant half (VL) or to the carboxyl-terminal, constant half (CL) of the Bence Jones protein. Analyses of urine specimens from such patients who... | 803,979 | [
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Interatrial septum in B-mode and conventional echocardiograms - a clue for the diagnosis of congenital heart diseases. | The interatrial septum was studied with B-mode echocardiography to determine whether there were specific ultrasonic features characteristic of such congenital heart diseases as atrial septal defect and endocardial cushion defect. In transverse tomograms in the third and fourth intercostal space the interatrial septum i... | 803,982 | [
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A new system for rapid review of clinical studies and more efficient group teaching in ultrasound. | Asystem using television in a convenient format is described. Its applications include rapid, convenient review of studies by clinicians and efficient presentation of data to groups of ultrasound trainees. The videotape capability of unit allows production of teaching aids for sharing with other labs. | 803,987 | [
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IgG on lymphocyte surfaces; technical problems and the significance of a third cell population. | Direct immunofluorescence performed with the F(ab)2 fragment of rabbit antibodies to IgG revealed that membrane bound IgG was only rarely found on the surface of small peripheral blood lymphocytes (PBL). In contrast whole antibodies to IgG used in fluorescence gave much higher levels of cells with IgG surface staining.... | 804,005 | [
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Pathogenesis of experimental allergic uveitis induced by retinal rod outer segments and pigment epithelium. | Experimental allergic unveitis (EAU) was produced in strain 13 guinea pigs after immunization with purified guinea pig retinal rod outer segments and pigment epithelium (PE) in mycobacterial adjuvant emulsion. The lesions of EAU appear as inflammatory infiltrates of the iris, ciliary body, and choroid, often with photo... | 804,008 | [
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Sarcocystis fusiformis infection in the coyote (Canis latrans). | Of 150 fecal samples from coyotes from northern Utah and southern Idaho, 21 contained coccidian sporocysts. These were found singly, contained four sporozoites and a granular residuum, and averaged 16.9 x 10.9 mum in size. None of four lambs inoculated with these sporocysts showed clinical signs of disease, and no para... | 804,020 | [
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Susceptibility of Anaerobic bacteria to carbenicillin, cefoxitin, and related drugs. | The agar dilution technique was used for determination of the bacteriostatic activity of carbenicillin, penicillin G, cefazolin, cephaloridine, cefoxitin, and cephalothin agaomst a variety of anaerobic bacteria. Carbenicillin showed a high level of activity at a concentration of smaller than or equal to 100 mug/ml; onl... | 804,023 | [
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Blood protozoa of imported birds. | Large numbers of birds, until recently, were brought into the United States each year. Countries of origin were varied, and included those of Australasia, Africa, South America, and the Caribbean islands, as well as other places. With them of course come their parasites, some of which may be potential pathogens to dome... | 804,038 | [
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The effects of thiazides on serum and urinary zinc in patients with renal calculi. | Urine zinc (Zn) excretion was significantly higher in 338 male patients with renal calculi than in 21 normal male subjects, but there was no significant difference between 102 female patients with renal calculi and 15 normal female subjects. In 33 patients with renal calculi urinary Zn was less than 50% of the mean nor... | 804,069 | [
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Biochemical parameters in the patas monkey. | Various difficulties are encountered when applying certain routine clinical chemistry procedures to biological material from patas monkeys. The wide range of results found in the immature monkey, together with findings which in the human subject would be grossly abnormal, are described. | 804,071 | [
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[Suicidal tendencies and the prevention of suicide (author's transl)]. | The high risk of suicide in depressions is emphasized and the psychotherapeutic aspects discussed. The methods of short crisis psychotherapy are set out in detail and finally the possibility of using psychoactive drugs for treatment is referred to. | 804,093 | [
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[The prevention of suicide by the Telefonseelsorge (author's transl)]. | The organisation which offers a 24-hour service of counselling and/or befriending to people who are suicidal risks or can themselves see no solution to their problems and difficulties, is known in Germany by the name of Telefonseelsorge. On the international level there exist norms for this work laid down by the Intern... | 804,097 | [
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On the relationship between the frequency of two types of lethal-mutation and x-ray doses in Drosophila. | The dose-frequency relationship for each of 2 types of lethal mutations, fractional- and whole-lethal, was obtained using X-rays on Drosophila melanogaster. The results show that fractional-lethal mutations are induced by X-rays, and also that the proportion of fractional-lethal mutations in the total of mutations tend... | 804,127 | [
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Serum thyroid hormones and thyrotropin in anorexia nervosa. | Sixteen patients with typical signs and symptoms of anorexia nervosa were studied with measurement of serum thyroxine (T4), triiodothyronine (T3) and thyrotropin (TSH), both baseline and stimulated by thyrotropin-releasing hormone (TRH). The results of the patients were compared with those of 16 normal control subjects... | 804,141 | [
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Child health care in the United States: expenditures and extent of coverage with selected comprehensive services. | This paper summarizes pertinent data on national health expenditures for children and youth. In fiscal year 1972, the average expenditure per child per year for health care from all sources in the United States was $147 for children and youth under 19 years of age, an amount 15% above that for the children and youth pr... | 804,158 | [
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Osteomyelitis and sepsis: severe complications of fetal monitoring. | Sophisticated modern methods of fetal monitoring during labor have improved the prognosis for high-risk infants, but the possible adverse side effects have not yet been fully documented. One infant with osteomyelitis and one with streptococcal sepsis are reported. In the future, greater attention should be paid to such... | 804,160 | [
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Cell-free translation of immunoglobulin messenger RNA from MOPC-315 plasmacytoma and MOPC-315 NR, a variant synthesizing only light chain. | Total poly(A)-containing mRNA was isolated from the MOPC-315 and MOPC-315 NR plasmacytomas. The RNA was further fractionated on sodium dodecyl sulfate-sucrose gradients. The MOPC-315 mRNA fractions directed the synthesis of both the heavy chain and light chain precursor of the MOPC-315 IgA protein in a cell-free extrac... | 804,169 | [
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The abnormal bone scan in intracranial lesions. | In 43 patients with abnormal brain scans restudied within 2-7 days with 99mTc-labeled ethane-1, hydroxy-1, diphosphonate (EHDP), cerebral infarctions, primary and metastatic neoplasms, chronic subdural hematoma, arteriovenous malformations and inflammatory lesions were visualized. The localization of EHDP in primary an... | 804,173 | [
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Fetal hemoglobin restriction to a few erythrocytes (F cells) in normal human adults. | During adult life, the quantity of fetal hemoglobin (HbF) present in F cells--that is, rare erythrocytes which are reactive with rabbit antiserum to human HbF during microscopic immunodiffusion--is sufficient to account for all of the small quantity (less than 0.7 percent) of HbF normally present in whole blood. Thus, ... | 804,182 | [
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Ultrastructural study of the relationship between immune cytotoxic lymphoid cells and target cells in vitro. | Ultrastructural details of the relationship in vitro between sensitized T lymphoid cells and YAC target cells are described. Within a few hours very close connections develop between these two cells. Narrow junctions with parallel plasma membranes and local evaginations of the lymphoid cell into recesses of the targe... | 804,208 | [
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Findings in routine laboratory examination in progressive myoclonus epilepsy. | Thirty-one patients suffering from progressive myoclonus epilepsy, (also called Unverricht-Lundborg's disease) without Lafora bodies, were examined to check the findings reported in literature and to chart out the main abnormalities in routine laboratory findings. Many alterations could be pointed out, but a high propo... | 804,227 | [
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Bacteremia and postmortem microbiology in burned children. | During a three-year period, Staphylococcus aureus and Pseudomonas aeruginosa were the organisms most commonly isolated from blood cultures of burned children. Microorganisms were considered to contribute to the cause of death in 17 of 20 patients who died from various complications of thermal injuries. Pseudomonas aeru... | 804,250 | [
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Coagulation changes in baboons during acute experimental hemoglobinemia and dextran infusion. | Evidence of disseminated intravascular coagulation (DIC) was dought in normal baboons infused with autologous hemolyzed whole blood, preceded or followed by infusion of dextran (molecular weight, 70,000). Mean peak plasma hemoglobin following a rapid single injection was 370 mg/100 ml in 2 animals and 1,236 mg/100 ml i... | 804,256 | [
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Lithium carbonate in the treatment of tardive dyskinesia. | Six patients with tardive dyskinesia were treated with lithium carbonate in an open clinical trial. Evaluations using a new tardive dyskinesia rating scale showed statistically significant improvement in dyskinetic movements while the patients received lithium. This improvement was consistently observed in all patients... | 804,260 | [
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Pathogenesis of acute avian malaria. II. Anemia mediated by a cold-active autohemagglutinin from the blood of chickens with acute Plasmodium gallinaceum infection. | A cold-active hemagglutinin for trypsinized human type "O" erythrocytes (CAH) from blood of chickens with acute Plasmodium gallinaceum malaria was found to be associated with 19 S and 7 S globulin fractions of malarious chicken blood, but cleavage with 2-mercaptoethanol indicated that it was primarily of the IgM class ... | 804,265 | [
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Phosphate utilization and alkaline phosphatase activity in Anacystis nidulans (Synechococcus). | Anacystis nidulans (Synechococcus) was maintained in a medium of low phosphate concentration (0.1 mM) and grew with a normal doubling time of 5 hrs at 30 degrees C. Such cultures had a normal pigment composition and alkaline phosphatase was detectable at low specific activities only. The onset of phosphate-limited grow... | 804,297 | [
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Olfactory neuroblastoma. Management and prognosis. | Olfactory neuroblastoma is an uncommon malignant tumor originating in the olfactory epithelium in the roof of the nose. It usually produces nasal obstruction and secondary sinus disease and is often mistaken by the physician for a nasal polyp. Olfactory neuroblastoma has been observed to cause death by distant metastas... | 804,302 | [
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The parenteral application of a new metacycline preparation, tri-metacycline. | Tri-metacycline, one of the new tetracycline complexes (tritetracyclines), is prepared by mere dissolution of metacycline hydrochloride in an aqueous solution of the complexing agent. In vitro and in vivo studies show a high antibiotic activity. Significantly lower MIC values were found for tri-metacycline than for t... | 804,312 | [
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... |
45Ca and (14C)EDTA efflux from dialyzed barnacle muscle fibers. | 45Ca and 14C-labeled ethylenediamine-N, N'-tetraacetic acid (EDTA) effluxes were measured in internally dialyzed barnacle muscle fibers. In 45Ca experiments the internal ionized 45Ca was fixed at 0.2 muM with ethyleneglycolbis-(beta-aminoethylether)-N, N'-tetraacetic acid(EGTA). The 45Ca efflux was found to increase wi... | 804,333 | [
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0.3030624,
-0.2459304,
0.3885661,
0.108414,
0.4041154,
0.1194688,
... |
Factor X Friuli: An immunological study in plasma and in serum using several methods. | An immunological study of factor X Friuli was carried out using an anti-human-factor X antiserum. The results obtained with different methods were compared. Only an ill-defined factor X band or precipitate was evident on standard immuno-electrophoresis and on immunodiffusion. Using a non-absorbed antiserum a precipitat... | 804,336 | [
-0.2949339,
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... |
Epidemiology of Pseudomonas aeruginosa infections investigated by pyocin typing. | All strains of Pseudomonas aeruginosa isolated in a large Canadian hospital over a 3-year period were typed by their pyocin production. Smaller collections of P. aeruginosa from other hospitals were also typed. Almost 3000 strains were examined. The typing method did not require use of complex reagents and was successf... | 804,346 | [
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Myocardial lesions induced by prolonged alcohol feeding in rhesus monkeys. | To elucidate the effects of chronic alcohol ingestion in monkeys a synthetic, adequately balanced, fluid diet providing 40% of total calories from ethanol was gavaged through a stomach tube daily over a period of three months. Clinical, biochemical, radioisotope, and histopathological studies were performed at the begi... | 804,351 | [
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... |
Drug metabolism in normal children, lead-poisoned children, and normal adults. | Drug-metabolizing capacities were determined in 10 normal adults and 10 children in the age range from 1 to 8 years. Among the latter, 2 were normal and 8 had biochemical evidence of lead poisoning but no clinical expression of plumbism. There were no differences between the 2 normal children and the 8 lead-poisoned ch... | 804,369 | [
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0.0... |
Stromal endometriosis. | The case histories of six patients with stromal endometriosis of the uterus have been studied. These patients had been referred with disease recurrent after hysterectomy for palliative radiotherapy, which four received with useful effect. The disease has a different natural history from the commoner endometrial sarcoma... | 804,373 | [
-0.05935161,
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0.2389184,
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0.2344808,
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Central nervous system effects of hypothalamic peptides. | Intravenous (i.v.) administration of TRF (1 mg/kg) increases the LD50 of pentobarbital (PB) by 25% while the same dose of somatostatin results in a 30% reduction in PB LD50. A similar increase of PB LD50 by TRF was observed in hypophysectomized rats. Mortality was completely abolished in rats receiving TRF (1 mg/kg) te... | 804,400 | [
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0.09135111,
0.01282752,
0.4039457,
0.1427391,
0.08340... |
Role of antibodies to galactocerebroside in experimental allergic encephalomyelitis. | The possible role of antibodies to galactocerebroside was investigated in AS rats with experimental allergic encephalomyelitis (EAE) induced by guinea-pig spinal cord. Passive immunization with rat or rabbit antiserum to galactocerebroside did not protect rats from EAE. Active immunization with galactocerebroside befor... | 804,435 | [
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0.07666562,
0.02158965,
0.2320028,
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-0... |
Biologically active components from mycobacterial cell walls. III. Production of experimental allergic encephalomyelitis in guinea-pigs. | The efficacy of various fractions of mycobacterial cell walls in producing experimental ahlergic encephalomyelitis (EAE) has been evaluated. BCG (Bacillus-Calmette-Buérin) cell walls were effective in producing EAE in all animals at dose levels as low as 40 mug. Study of subfractions of these cell walls revealed the fo... | 804,436 | [
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0.09597858,
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Requirement for a bone marrow-derived component in the expression of cell-mediated antibacterial immunity. | Mice were X irradiated with 400 R and 1 week post-irradiation were found to be unable to develop antilisterial immunity after active or passive immunization with immunologically committed spleen lymphocytes from Listeria-immune donors. This consequence of irradiation disappeared spontaneously within 21 days of exposure... | 804,449 | [
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0.4518402,
0.5776606,
0.05152718,
-0.03675... |
Quantitation of Salmonella O-antibodies in human sera by enzyme-linked immunosorbent assay (ELISA). | The enzyme-linked immunosorbent assay (ELISA) has been applied to the detection of antibodies against Salmonella O-antigens in human sera. Phenol-water extracted lipopolysaccharides (LPS) from serogroups A (O-antigens 2, 12), B (4, 5, 12) and D (9, 12) were used as antigens. When compared to the tube agglutination meth... | 804,453 | [
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... |
Changes in the antigenic composition of cultured bovine corneas. | Several immunologic tests were used to compare the soluble antigens of cultured and normal bovine corneas. Results of fluorescent-antibody tests on normal corneas confirmed our earlier observation that the epithelium contained little serum protein, and that stroma and epithelium shared an antigen not found in bovine s... | 804,460 | [
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0.1463851,
0.049... |
Genetic transfer of Pseudomonas aeruginosa R factors to plant pathogenic Erwinia species. | The R factors RP1, R68 and R91 were freely transmissible to and from Pseudomonas aeruginosa, Salmonella typhimurium, and various plant pathogenic Erwinia spp. The antibiotic resistance spectrum of R+ Erwinia recipients was similar to those of other bacteria harboring these R factors, but maximum resistance levels diffe... | 804,467 | [
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... |
Different nuclease activities in competent and noncompetent Bacillus subtilis. | Competent and noncompetent cells of Bacillus subtilis were separated on the basis of their different buoyant densities. The two types of cells were compared with respect to their interactions with exogenous deoxyribonucleic acid(DNA). After exposure of DNA to the cells, the unadsorbed fraction of DNA molecules was exam... | 804,469 | [
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0.7985787,
0.05627897,
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Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vitro. An adenine nucleotide-dependent reaction catalyzed by a factor in human fibroblasts. | Microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase prepared from either rat liver or human fibroblasts was shown to be inactivated in vitro by a factor in extracts of cultured human fibroblasts in a reaction requiring ATP or ADP and Mg2+ or Mn2+. The inactivation factor was found in the soluble fraction of fibr... | 804,475 | [
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0... |
Amino acid sequence of tuberculin-active protein from Mycobacterium tuberculosis. | The complete amino acid sequence of tuberculin-active protein from tubercle bacilli was determined. The sequences of residues of tryptic, chymotryptic, and peptic peptides were established by Edman degradation and dansylation (5-dimethylaminonaphthalene-1-sulfonyl) and by digestion with carboxypeptidases A and B. Certa... | 804,477 | [
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0.... |
Escherichia coli 30 S ribosomal proteins uniquely required for assembly. | Two 30 S ribosomal proteins from Escherichia coli have been found to be uniquely required for assembly of 30 S ribosomal subunits. 30 S ribosomes were reconstituted in vitro from 16 S RNA and a mixture of purified 30 S ribosomal proteins (sigma Si). In the absence of S16, sigmaSi-S16 particles were slowly assembled wic... | 804,486 | [
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A membrane filter technique for testing disinfectants. | A membrane filter was used for assessing the surface disinfecting activity of phenolic disinfectants and a chloroxylenol disinfectant. The influence of the type of organism, inoculum size, and hardness of water was investigated. Pseudomonas aeruginosa was chosen for the standardized test. Disinfectant solutions were pr... | 804,497 | [
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0.01420539,
0.2321474,
0.03510344,
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Alternate complement pathway induction of aggregation and release of 5-hydroxytryptamine and adenosine diphosphate by rabbit platelets. | The present studies investigated patterns of rabbit platelet aggregation and release of 5-hydroxytryptamine (5HT) utilizing nine variables: three different types of challenge, soluble antigen and antibody (AG-AB), zymosan (Z), an agent known to activate the alternate complement pathway (ACP), and Z preincubated in ligh... | 804,512 | [
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... |
The induction of delayed hypersensitivity in guinea pigs to poly U and poly A:U. | Guinea pigs were sensitized to poly U and poly A:U so that subsequent stimulation of spleen cells from these immunized animals with poly U and poly A:U resulted in the production of migration inhibitory factor (MIF). MIF was also produced when spleen cells from animals immunized with poly A:U were cultured in the prese... | 804,517 | [
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... |
Involvement of tyrosinase in melanin formation in murine melanoma. | The possibility that peroxidase is functional in melanogenesis in the murine S-91 melanoma has been investigated. It was found that, as in the normal mouse, tyrosinase is the enzyme responsible for the bulk of melanin formation in the malignant melanocyte. Tyrosinase was capable of utilizing tyrosine as a substrate, as... | 804,529 | [
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0... |
Myocardial infarction without atherosclerosis. | By far the most frequent pathologic condition preceding myocardial infarction is coronary atherosclerosis. Because the great majority of patients who are first seen with acute myocardial infarction have atherosclerotic coronary artery disease, there is usually little thought given to other causes, except in children wh... | 804,570 | [
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... |
Evaluation of chromic oxide, glycerol triether, and beta-sitosterol as fecal flow markers in two species of nonhuman primates. | Recovery of beta-sitosterol, glycerol triether (1-hexadecyl-2,3-didodecyl glycerol triether), and chromic oxide was studied in African green monkeys and stumptail macaques consuming diets containing 0.75 mg/Cal cholesterol and 38% of calories as safflower oil or butter. Following oral administration of these compounds,... | 804,580 | [
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0.4651732,
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0.2732826,
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... |
[Allergic reactions of the eczema type due to drugs (author's transl)]. | Drug-induced allergic skin reactions of the eczema type may relatively frequently appear as allergic contact eczema or more rarely as "hematogenous contact eczema." In both types of eczema, a positive patch test to one or more allergens is essential for diagnosis. In 1971 and 1972, there were 85 patients with drug-indu... | 804,596 | [
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0.2237534,
0.02679924,
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0.1962272,
0.08959052,
0.0861082... |
[Camptodactylia. A study of 33 cases]. | A marked camptodactylia, or a mere suggestion of it, was found in 91 (56; 5%) of 161 mentally ill patients, particularly in psychopaths, neurotics and patients in a neurotic state. Clinical, psychological, radiological and biological investigations were carried out in 33 patients. The camptodactylia was frequently asso... | 804,600 | [
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0.2198808,
0.2644396,
0.1137494,
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... |
[Results of physical therapy of peripheral arterial circulatory disorders (V). Therapeutic success of different durations of physiotherapeutic exercises]. | The effect of physiotherapeutic exercise treatments of various duration was investigated in 5 collectives of ambulant patients comparable with respect to age, duration of illness, site of occlusion and risk factors (133 patients). The standardized walking distance test was used as the criterion of the treatment. There ... | 804,622 | [
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0.2392612,
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0.52837,
-0.004467246,
-0.08071072,
-0.... |
[Results of physical therapy of peripheral arterial circulatory disorders (VI). Present position of the results in the Steglitz Hospital, Berlin]. | 103 patients with peripheral arterial circulatory disorders of Fontaine's type II were divided into 3 comparable groups and subjected to physiotherapeutic interval training three times a week for 7-8 weeks and 10-12 weeks respectively (Groups I and II) and Group III to similar intensive therapy five times a week for 6-... | 804,623 | [
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0.5833565,
0.1028749,
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0.01393205,
... |
[Hemoblastosis and genital manifestations (author's transl)]. | The course of the disease in a woman with a malignant lymphoma is described. The primary disease was recognized through an early involvement of the uterus which led to hemorrhages. While observations of this kind are relatively seldom communicated, examination of the literature showed that involvement of the genitals i... | 804,635 | [
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-0.07975,
... |
[Mesenteric lymphadenitis (author's transl)]. | In 23 years the mesenteric lymphadenitis syndrome has been observed more closely in 4974 appendectomies. Examination of the fine structure of the lymph nodes removed showed a non-specific catarrhal inflammation, while a tubercular disease of the lymph nodes could not be demonstrated in any case. After removal of the ap... | 804,636 | [
-0.07018811,
-0.193916,
-0.07273946,
0.08309002,
-0.1084082,
-0.2430338,
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-0.1965949,
0.1113085,
0.001079449,
0.1344591,
-0.299196,
0.1649508,
0.008684729,
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-0.4248607,
0.1630855,
-0.0125085,
0.3768312,
0.218648,
-0.1206177,
-0.04449749,... |
[Special features of the duties of a gynecologist in Islamic countries (author's transl)]. | A European gynecologist who takes up his duties in a developing Mohammedan country encounters very different problems compared to those in Europe: Early marriage is customary, the intact hymen has great significance. The "child" primipara is the "normal" primipara. Obstetric actions are not determined by the high value... | 804,640 | [
0.1416788,
0.118717,
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0.2169092,
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0.08279824,
0.1075626,
0.1225997,
0.05922947,
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0.227551,
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-0.1133291,
0.4536172,
0.1168948,
0.07594437,
0.1... |
[Controlled trial of Cymbi on efficacy and tolerance (author's transl)]. | Ampicillin (Cymbi -Dolorgiet) was administered in various administration forms to 139 patients with acute and chronic infections of the urinary tract, biliary tract and other infections for an average of 10 days under conditions similar to those of general practice. In a controlled investigation the efficacy and tolera... | 804,644 | [
-0.03845734,
-0.08629996,
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0.06536166,
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0.112848,
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0.5108321,
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0.134523,
-0.2556142,
0.2481976,
0.3310391,
0.1253177,
0.05688551,
... |
[Effect of infections on the course and effectiveness of epilepsy treatment in children]. | The analysis was carried out in a group of 32 children with coexistent chronic urinary tract or respiratory infections. In 20 children an unfavourable effect of infection on the course of epilepsy was observed. Worsening of epilepsy during infection was observed mainly in children without evidence of nervous system dam... | 804,669 | [
0.0103599,
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0.09010305,
0.09851059,
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0.3004008,
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0.3265064,
0.1716341,
0.1231276,
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-0.08596745,
0.2466785,
-0.09821738,
0.1909393,
0.1447047,
-0.002920668,
-0.10169... |
Adaptive changes in degree of eye reduction in eyeless mutants of Drosophila melanogaster after thermal shock during the critical periods of faceted eye development. | Brief heating of the oocytes and larvae of eyeless mutants during the critical periods of faceted-eye development caused an increase in the thermal sensitivity of the eye rudiments, which led to an increase in the number of one-eyed individuals among the flies that hatched. These changes eye development were transmitt... | 804,720 | [
0.2123056,
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0.297562,
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0.01876605,
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0.02971043,
0.2917474,
-0.1132318,
... |
Moschcowitz syndrome with involvement of the central nervous system. Light optical studies on the genesis of hemolytic anemia and vascular changes. | The origin of hemolytic anemia, the histogenesis of vascular changes and the origin of prethrombotic lesion are discussed in a typical case of thrombotic thrombocytopenic purpura (TTP) with early neurological symptoms. The disease arose after exposure to a chloronaphtalene containing substance. In addition to the typic... | 804,758 | [
-0.03346837,
0.08976728,
0.003157645,
0.06074647,
0.5258577,
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0.136776,
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0.244865,
0.02207874,
0.2876379,
0.1369682,
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0.09335057,
0.1654275,
0.5266999,
0.2012019,
0.4379773,
-0.149665,
-0.313... |
Hepatitis B antigen and antibody in active chronic hepatitis and other liver diseases in Australia. A multicenter collaborative study. | In a multicenter cooperative study, sera from 85 patients with active chronic hepatitis (ACH) were examined for the presence of hepatitis B (Australia) antigen (HBAg) by radioimmunoassay (RIA) and antibody to HBAg (anti-HBAg) by RIA and passive hemagglutination (PHA), the most sensitive currently available techniques. ... | 804,811 | [
0.07463077,
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0.01899152,
0.03756531,
0.1240624,
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0.2769387,
0.09317568,
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-0.3449273,
0.1281102,
0.1283284,
-0.1647319,
0.08640167,
0.0353741,
-0.001... |
World Health Organization studies on bacteriophage typing of mycobacteria. Subdivision of the species Mycobacterium tuberculosis. | The ability of lytic mycobacteriophages to subdivide the species Mycobacterium tuberculosis reliably has been studied using a series of 100 strains isolated from cases of tuberculosis in the Netherlands. Techniques for the propagation and application of the viruses have been standardized, as have the conditions for gro... | 804,840 | [
-0.1964479,
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0.02661956,
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0.2318873,
0.09525531,
-0.1147616,
0.3901648,
0.2199721,
-0.336078... |
Effects of bicarbonate on growth of Neisseria gonorrhoeae: replacement of gaseous CO2 atmosphere. | The effect of NaHCO2 on the growth of Neisseria gonorrhoeae cultures was studied in a liquid and a semisolid growth medium. With a broth culture, NaHCO3 (0.009 M) greatly reduced the lag phase and also increased the total growth. The same concentration of bicarbonate supported rapid growth when added to the semisolid m... | 804,849 | [
-0.1181577,
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0.1901045,
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-0.3772347,
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0.2078637,
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0.0929134,
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-0.04900777,
0.3103622,
-0.2052103,
0.1141738,
0.3508611,
0.2539366,
0.1832934,
... |
H2 production by Selenomonas ruminantium in the absence and presence of methanogenic bacteria. | Selenomonas ruminantium is a nonsporeforming anaerobe that ferments carbohydrates primarily to lactate, propionate, acetate and CO2. H2 production by this species has not been previously reported. We found, however, that some strains produce trace amounts of H2 which can be detected by sensitive gas chromatographic pro... | 804,850 | [
-0.2935346,
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-0.1094108,
0.2613271,
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0.02011199,
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-0.209283,
0.07834571,
0.01216839,
0.05309606,
-0.006815671,
-0.002120574,
0.0832... |
[Treatment of Laubry-Pezzi syndrome apropos of a case in a 7-year-old child]. | Report of one case of a Laubry and Pezzi syndrome. In spite of the already severe aortic incompetence at the age of 4 years, operation was postponed. Three years later, at the first signs of bad tolerance of the aortic incompetence the operation was undertaken including: -- closure of the ventricular septal defect by a... | 804,870 | [
-0.1591034,
0.01396405,
-0.1672033,
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0.03669036,
0.2055137,
0.1432755,
0.268032,
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0.01665173,
0.01817681,
-0.01903777,
0.5161141,
0.2823482,
0.09621441,
... |
[Values of glucose, potassium and inorganic phosphate as metabolic indicators of myocardial ischemia in humans]. | In 34 patients with coronary atherosclerosis a pacing test was performed with measurement of the lactate, glucose, potassium and inorganic phosphate coronary arterio-venous differences. Eighteen of these 34 patients felt no pain during the pacing test. In this group of asymptomatic patients, there was no significant ch... | 804,887 | [
-0.09013826,
0.1561197,
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0.04563316,
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-0.4202728,
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0.2561619,
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-0.6227632,
0.2296383,
0.1458108,
0.2540879,
0.2336752,
-0.1269437,
-0.0002220234,... |
[Anatomic aspects of Prinzmetal's angina: apropos of an anatomo-clinical case]. | Report of one case of Prinzmetal variant of angina pectoris with a typical clinical and electrocardiographic picture in a man aged 87. Severe arrhythmias resulted in death of the patient. On autopsy a moderate narrowing of the anterior interventricular artery was demonstrated. In that relation, a review of the literatu... | 804,889 | [
-0.2864862,
0.2214851,
-0.2156388,
-0.05839822,
-0.08238749,
-0.1607822,
-0.4473624,
-0.05109946,
0.1528215,
-0.1258604,
0.2166151,
0.2452235,
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-0.08397484,
0.2279755,
0.3961479,
-0.06518005,
0.4417446,
0.1230326,
-0.1425912,... |
[Funnel-chest and cardio-pericardial pathology, apropos of 2 cases treated by pericardioplasty and parietal remodelling]. | Numerous pathogenic hypotheses were put forward to explain the Funnel Chest. It is possible that the origin of this malformation is not related to an involvement of the thoracic wall or the diaphragm, but rather to a negative pressure behind the sternum which is attracted by inspiratory movements, this resulting in, an... | 804,892 | [
-0.3638114,
0.2341347,
-0.2038775,
-0.1542809,
0.2576913,
-0.2010116,
-0.3899911,
-0.0610933,
0.1178257,
0.05939563,
0.1008373,
0.01864642,
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-0.1772976,
-0.3186551,
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-0.3858373,
-0.1887011,
-0.05231702,
-0.03792305,
0.1335386,
0.1852573,
-0.2527853,
... |
Photoexcited bacterial luminescence. Spectral properties and mechanistic implication of a reduced flavine-like prosthetic group associated with photoexcitable luciferase. | A prosthetic group, designated B, has been isolated from bacterial photoexcitable luciferase and found to possess spectral and photochemical properties characteristic of substituted reduced flavines. Its fluorescence when bound to luciferase has an excitation maximum at 375 nm, correlating well with the absorption spec... | 804,918 | [
-0.3019127,
-0.0698251,
-0.4120238,
-0.01237967,
-0.05501365,
-0.1566702,
-0.1687966,
0.1162426,
0.2041638,
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0.2474355,
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0.1331246,
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0.1612777,
-0.513291,
0.06977548,
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0.2572698,
0.5917261,
0.187272,
0.03417812,
... |
Flash kinetics and light intensity dependence of oxygen evolution in the blue-green alga Anacystis nidulans. | Patterns of oxygen evolution in flashing light for the glue-green alga Anacystis nidulans are compared with those for broken spinach chloroplasts and whole cells of the green alga Chlorella pyrenoidosa. The oscillations of oxygen yield with flash number that occur in both Anacystis and Chlorella, display a greater deg... | 804,933 | [
-0.21623,
0.02979694,
-0.3028625,
0.1367733,
-0.3970053,
0.07546633,
-0.0464303,
-0.07504638,
0.303876,
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0.2506047,
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-0.3150425,
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0.2381731,
0.1645744,
0.1732871,
0.1702132,
-0.3144958,
0.064... |
Experimentally determined tissue air ratios and scatter air ratios for collimated beams of 14 mev neutrons. | Tissue air ratios (TAR) and scatter air ratios (SAR) for collimated beams of 14 MeV neutrons were determined from depth dose curves measured in air and water using a tissue equivalent proportional counter. Central axis depth dose data were obtained as a function of field size and depth in a water phantom for an SSD or ... | 804,946 | [
-0.2530552,
-0.04596809,
-0.03855569,
-0.1811742,
0.06538862,
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0.05547312,
0.002719325,
0.08450208,
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0.383051,
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0.08193436,
0.04379781,
0.2272454,
0.2151119,
-0.04676811,
0.032... |
Indirect fluorescence test for the detection of anti-gonoccocal antibodies. | (1) An indirect fluorescence test for the detection of anti-gonococcal antibody is described. (2) Positive results at a serum dilution of 1 in 16 or above were obtained with sera from 20 per cent. of males and 61 per cent. of females with bacteriologically proven gonorrhoea. 3-8 per cent. of presumed false positive res... | 804,958 | [
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0.03338373,
0.06348823,
0.1362472,
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0.1161719,
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0.2119104,
0.4060199,
0.1824106,
0.174907,
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0.3767793,
-0.4605921,
0.1068873,
0.3354065,
-0.05607408,
0.09735008,
0... |
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