title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Co-trimoxazole for prevention of infection in acute leukaemia. | 30 patients with acute leukaemia being treated with cytotoxic drugs were investigated in a randomised trial to determine whether oral administration of co-trimoxazole in addition to non-absorbable antibiotics would reduce the rate of infection. Three significant differences were observed between the co-trmoxazole and t... | 79,761 | [
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Does that child really have cystic fibrosis? | A diagnosis of cystic fibrosis was incorrectly made after false-positive sweat tests in 14 children. 13 of these children had been tested at hospitals where it seems likely that sweat tests were not done very often. All the children had normal sweat-electrolyte values when the test was repeated at a regional paediatric... | 79,773 | [
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Renin and blood-pressure in children with renal scarring and vesicoureteric reflux. | Plasma-renin-activity (P.R.A.) was raised in 9 of 15 hypertensive children with pyelonephritic scarring secondary to urinary-tract infection and vesicoureteric reflux and also in 8 of 100 normotensive children with such scars. P.R.A. was much less likely to fall with age in normotensive children with renal scarring tha... | 79,805 | [
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Prevention of acute porphyric attacks by intravenous haematin. | A thirty-three-year-old female with acute intermittent porphyria (A.I.P.) was having regular attacks of the disease with her menstrual periods. During several of these attacks she received intravenous haematin, which was followed by chemical and clinical remissions. Hormones failed to prevent the regular attacks, which... | 79,864 | [
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Haemoglobin A1, blood glucose, and high-density lipoprotein cholesterol in insulin-requiring diabetics. | In forty insulin-requiring diabetics there was a significant correlation between haemoglobin A1 (HbA1) and blood-glucose measured at the same time and mean clinic blood-glucose measured over the previous year. There was no significant correlation between high-density lipoprotein (H.D.L.) cholesterol concentration and H... | 79,916 | [
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Protective effect of dietary fibre against chemically induced bowel tumours in rats. | 101 rats were fed one of four diets containing graded amounts of dietary fibre. Subcutaeous dimethylhydrazine (D.M.H.) was given to half the rats in each of the diet groups. Stool mass was found to be directly related to the amount of dietary fibre consumed, and the incidence of D.M.H.-induced colon carcinoma was reduc... | 79,919 | [
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Drug-induced myopathies in man. | Drug-induced diseases constitute up to 5% of hospital admissions,a figure which almost certainly understates the total morbidity due to drugs1. Sever drug-induced myopathies are uncommon, but milder forms may be more prevalent than is generally appreciated, since skeletal muscle constitutes some 45% of total body-weigh... | 79,927 | [
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[Treatment of algodystrophic syndromes with calcitonin]. | A general account of algodystrophic syndromes is followed by the presentation of results obtained with 160 MRC U/day extracted pig or 100 MRC U/day synthetic salmon calcitonin in 95 patients with the most common form (Sudeck's syndrome). Clinical, biohumoral and radiographic data are reported. There was no difference i... | 79,988 | [
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Effects of zinc sulphate pretreatment on gastric acid secretion and lesion formation in rats infused intravenously with graded doses of methacholine. | The effects of intraperitoneal pretreatment with zinc sulphate (22, 44 or 88 mg/kg) were studied on gastric acid secretion and lesion formation induced by methacholine (125, 250 or 500 microgram/kg/h) infused intravenously in rats with stomachs perfused in situ. Graded infusions of methacholine produced dose-dependent ... | 80,014 | [
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Urinary excretion of albumin and beta 2-microglobulin in a population from an area where Balkan nephropathy is endemic. | The urinary excretion of albumin and beta 2-microglobulin in a population of 294 persons, living in an area where Balkan nephropathy is endemic, has been studied. In fifty-six (about 19%) of the subjects the beta 2-microglobulin concentration was above the +2 SD level for a reference group of healthy individuals from n... | 80,021 | [
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Analysis of mechanisms of maintenance of neonatally induced tolerance to foreign alloantigens. | Mice made tolerant to allogeneic tissues in neonatal life have been examined at different times for their ability to respond to the tolerizing determinants in a variety of assays (in vitro CML, MCL and in vivo GvH assays). All animals were tolerant in terms of their inability to produce CTL to the relevant determinants... | 80,023 | [
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Induction of specific unresponsiveness to transplantation antigens. | Transplantation of tissue between non-identical human beings does normally require heavy, non-specific immunosuppressive treatment to be successful. Complications of severe nature are frequently induced by such therapy. Here, procedures allowing a selective immunosuppression of the recipient with regard to the donor's ... | 80,026 | [
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[Multiple cartilaginous exostoses and neoplastic degeneration: review of the literature (author's transl)]. | In about 10% of patients suffering from multiple osteochondroma a malignant degeneration of one osteochondroma occurs. Data of 59 patients are collected from the literature. The malignant degeneration occurs at the age of 31 in average, mostly on the pelvic girdle, less frequently on the shoulder girdle and on the ribs... | 80,065 | [
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The Langerhans cell: its origin, nature, and function. | This is the biography of a cell--a cell as elusive and as deceiving as any in medical literature. This is the biography of the Langerhans cell, literally a cell at our fingertips, yet seemingly always beyond our intellectual grasp. Here is the story of a foundling within our epidermis, yet outside our pathologist's dai... | 80,092 | [
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Precordial mechanical stimulation for exposing electrical instability in the ischemic heart. | Sequenital mechanical pulsing of the chest wall with three stimuli failed to induce arrhythmias in normal dogs. After coronary arterial occlusion, this technique evoked in 11 of 12 animals repetitive ventricular tachycardia in 2. These responses corresponded closely to those elicited by electrical testing. In four cons... | 80,127 | [
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[Discussion of the interest of estimation of hydroxyprolinuria in chronic alcoholism (author's transl)]. | 24 hour hydroxyprolinuria was measured in 50 chronic alcoholics divided up into those with simple alcoholism and those complicated by cirrhosis. All the patients had a significant increase in hydroxyprolinuria. Without there being any difference between cirrhotics and alcoholics without cirrhosis. Comparison between hy... | 80,146 | [
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Subcellular structure of bovine thyroid gland. VII. A study on the distribution of bovine thyroid plasma membranes by density gradient centrifugation in zonal rotors. | In order to obtain plasma membrane-rich fractions two methods were tried. Approach A was based on differential pelleting followed by discontinous gradient centrifugation in a B-XIV zonal rotor. In approach B homogeneization was performed in buffered water (NaHCO3, pH 7.4). The 73 300 X g pellet from this homogenate was... | 80,197 | [
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Inhibitor of trypsin and chymotrypsin in cultures of HeLa cells. | An inhibitor of trypsin and chymotrypsin with apparent molecular weight of 68 000 and a mobility similar to alpha1-globulin on polyacrylamide gel electrophoresis, was isolated from serum-free supernatant preparations from HeLa cells. Immunoelectrophoresis assays indicated that the inhibitor differed serologically from ... | 80,230 | [
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Search for endogenous C-type viruses in cultures of non leukemic human cells. | Cultures of cells derived from non-leukemic human tissues were submitted to treatments known to induce endogenous C-type viruses of a number of animal species. Virus expression was evaluated by reverse transcriptase (RT) assays in the growth medium. Of 20 cultures treated or untreated with bromodeoxyuridine, 18 were to... | 80,236 | [
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Type D primate retroviruses: a review. | The prototype virus of the type D retroviruses is the Mason-Pfizer monkey virus (MPMV). MPMV was originally isolated from a breast carcinoma of a female rhesus monkey (an Old World monkey). MPMV is of obvious importance in that it is the only retrovirus thus far isolated from a mammary tumor of a primate and has been s... | 80,259 | [
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Expression of a Forssman antigenic specificity in the preimplantation mouse embryo. | A monoclonal antibody recognizing a Forssman antigenic specificity has been shown to react with cells of the preimplantation mouse embryo. The antigen is believed to be carried on glycolipid molecules on teratocarcinoma stem cells. This antigen is first detected on the trophectoderm of the early blastocyst. The topogra... | 80,282 | [
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Nomenclature for factors of the HLA system, 1977. | This article gives the decisions of the WHO nomenclature committee on leukocyte antigens, in particular concerning (a) the upgrading of certain HLA-A and HLA-B specificities to full HLA status, (b) the designation of new provisional specificities of the HLA-B, HLA-C, and HLA-D loci, and (c) the establishment of a nomen... | 80,288 | [
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[Evaluation of internationally used blood stabilizers for effective erythrocyte substitution]. | Haemotherapy developed in the direction of transfusing pure blood cell preparations, if possible and enlarging the therapy with plasma fraction considerably. Quality losses of haemotherapeutics will already occur when they are prepared. This is mainly due to the conditions of blood collecting, blood stabiliser, duratio... | 80,369 | [
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Hepatitis B surface antigen-specific cell-mediated immune responses in human chronic hepatitis B surface antigen carriers. | The presence of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs), hepatitis B e antigen (HBeAg) and antibody (anti-HBe), the nature of T-cell function, and specific cell-mediated immunity to HBsAg were determined and evaluated serially in groups of subjects with chronic HBsAg carrier states and in seronegati... | 80,380 | [
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Significance of noncapsular antigens in protection against experimental Haemophilus influenzae type b disease: cross-reactivity. | A bacterial strain, tentatively identified as an Actinobacillus species, was found to asymptomatically colonize the pharynx of some rats and to bear cell wall antigens which cross-react with noncapsular antigens of Haemophilus influenzae type b (HIb). The cross-reacting antigens appeared to be a heterogeneous mixture w... | 80,382 | [
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The aldehyde fuchsin and colloidal iron staining reactions in the canine thyroid C cell. | The cytochemically reactive groups which are responsible for Aldehyde Fuchsin (AF) and colloidal iron (CI) staining of C cells were investigated in the canine thyroid gland. To this end, stains for proteoglycans and peptide groups were utilized in conjuction with hydrolysis of glycosidic and amide bonds. In addition, t... | 80,395 | [
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On the specificity of alcoholic acidic silver nitrate reagent for the histochemical localization of ascorbic acid. A reappraisal. | The specificity of the alcoholic acidic silver nitrate staining method for the histochemical localization of ascorbic acid was reappraised. It was found that the method is by and large better suited for the localization of ascorbic acid in both animal and plant tissues due to its greater specificity, which is ensured b... | 80,400 | [
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Immunostaining of growth hormone and prolactin in paraffin-embedded and stored or previously stained materials. | In attempts to evaluate immunocytochemically autopsy and biopsy material previously obtained and processed for conventional histologic staining, we had to resort to immunostaining of tissues embedded years ago or even sections already stained with hematoxylin-eosin or aldehyde thionin-PAS-orange G. Hypophysial growth h... | 80,416 | [
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0.1465767,
0.5351272,
0.06520391,
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0.2799926,
-0.5017208,
0.06815682,
-0.01140154,
0.3970719,
0.2341545,
0.1165052,
-0.4753059,
... |
Rabbit latent group a allotypes: characterization and relationship to nominal group a allotypic specificities. | Latent group a allotypes were detected with a sensitive radioimmune inhibition assay. Sera, IgG preparations, and antibody fractions containing these allotypes inhibited the binding of insolubilized allotypic antisera to various radiolabeled antigens including IgG pools, homogeneous antibodies, and, in the case of a3, ... | 80,425 | [
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0.3942236,
0.1658018,
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0.2599... |
Nature of the antigenic complex recognized by T lymphocytes. VII. Evidence for an association between TNP-conjugated macrophage membrane components and Ia antigens. | In the present study we examined the effects of anti-sera directed against guinea pig Ia antigens on the ability of TNP-conjugated macrophages to stimulate TNP-specific T lymphocyte proliferation. Treatment of macrophages with anti-Ia sera for 1 hr before, 1 hr immediately after, or as late as 24 hr after TNP-modificat... | 80,427 | [
-0.1224321,
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0.281076,
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0.2476954,
0.004479927,
0.2601203,
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-... |
Radioimmunoassay for the detection of hepatitis e antigen (HBeAG) and antibody (anti-HBe). | A solid phase micro-immunoradiometric assay (micro-SPIRA) for the detection of hepatitis e antigen (HBeAg) and antibody has been developed. Chimpanzee anti-HBe/2 was developed by repeated immunizations with purified antigen containing HBeAg/1 and HBeAg/2. An anti-HBe/2 titer of 1:4 was determined by immunodiffusion (ID... | 80,434 | [
-0.08887219,
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0.2684679,
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0.01017747,
0.4520192,
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0.007841255,
-... |
The correlation of bacteriophage types of Mycobacterium tuberculosis with guinea-pig virulence and in vitro-indicators of virulence. | Among 58 isoniazid-sensitive strains of Mycobacterium tuberculosis from India, Burma and East Africa, 23 were of phage type A, 31 of type I (intermediate), 4 of type B and none of type C. Type I strains differed from type A strains in being attenuated in the guinea-pig, susceptible to H2O2, sensitive to thiophen-2-carb... | 80,440 | [
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0.4515661,
0.07194861,
0.2819466,
0.03665584,
-0.1289792,... |
Immunologic methods for the identification of cell types. II. Expression of normal mouse mammary epithelial cell antigens in mammary neoplasia. | Mouse mammary epithelial (MME) cell antigens were cell type-specific and were retained, to a large extent, by MME cells after neoplastic transformation. These MME cell antigens were expressed in mammary tumors of BALB/c, C3H, GRS/A, RIII, and Is/Bi mice tested and were not expressed in tumors whose normal counterpart w... | 80,454 | [
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0.2736637,
0.2341437,
0.2795637,
0.04055189,
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... |
Antimicrobial resistance and enterotoxin production among isolates of Escherichia coli in the Far East. | The frequency of association between transferable extrachromosomal D.N.A. (plasmid) mediated antibiotic resistance and enterotoxin productin is unknown. The antimicrobial susceptibility of 176 enterotoxigenic Escherichia coli from 57 children and adults in the Philippines, Korea, Taiwan, and Indonesia has been examined... | 80,523 | [
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0.2230981,
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0.003117332,
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0.1705305,
0.1904565,
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-0.0... |
Comparison of tienilic acid with cyclopenthiazide in hyperuricaemic hypertensive patients. | Tienilic acid, a diuretic with uricosuric properties, was compared with cyclopenthiazide, in an open, random-order, within-patient crossover study (3 months on each drug) in 36 hyperuricaemic hypertensive patients. All were on an established dose of cyclopenthiazide; most were also on a beta-blocker which they continue... | 80,525 | [
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0.1733525,
0.0175513,
0.1906796,
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... |
Subcutaneous ancrod in prevention of deep-vein thrombosis after operation for fractured neck of femur. | In a randomised double-blind controlled trial 53 patients received 5 daily subcutaneous injections of ancrod ('Arvin') after operation for fractured neck of femur, and 52 patients received saline fractured neck of femur, and 52 patients received saline injections. Deep-vein thrombosis (D.V.T.) was detected by bilateral... | 80,632 | [
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0.3595369,
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0.007909732,
0.2871131,
0.1744765,
0.344906,
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0... |
Possible diagnostic test for Crohn's disease by use of buccal mucosa. | Immunofluorescent tracing was used on buccal mucosa from patients with Crohn's disease to investigate some of its immunological characteristics, and to compare these with those of mucosa from controls. Normal buccal mucosa from patients with Crohn's disease, incubated with its own serum then stained for deposited antib... | 80,686 | [
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0.1525003,
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0.1982621,
0.3361856,
0.02280438,
0.1582596,
... |
Cervical cancer in younger women. | Cervical cancer does not begin in women at some vague mid-procreative term, but is a concomitant of early sexual activity. In Brighton the mean age of patients with histologically proven carcinoma of the cervix has been falling, from 50 in 1967 to 35 by 1977. In one year abnormal cells were found in cervical smears fro... | 80,696 | [
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0.1141397,
0.2671136,
0.08304279,
0.01189114,
0.7062511,
0.2978907,
-0.01741569... |
The retrovirus particles in human myeloma cells RPMI8226: morphological, biochemical, immunological and infective transmission studies. | The retrovirus designated RPMI8226V (isolated from human myeloma cells RPMI8226) has been characterized with respect to its morphological, biochemical and immunological properties as well as its propagation in various animal and human cells. The myeloma cells RPMI8226 produce intracytoplasmatic A-type particles and ext... | 80,755 | [
-0.2538936,
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0.1237526,
0.3559316,
0.07162064,
-0.1239374,
0.02... |
Checking of carcinoma patients with the leukocyte migration technique (LMT) under agarose. | Leukocyte migration tests under agarose (Clausen technique) were performed in 28 patients tentatively diagnosed as having any malignancy with the use of a 3 M KCl-extract panel prepared from bronchogenic, gastric, colonic, renal, and mammary carcinoma, corresponding normal tissues, carcinoembryonic antigen (CEA), and h... | 80,756 | [
-0.08128209,
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0.05750014,
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0.2060853,
0.2511333,
0.3301438,
0.07868285,
0.... |
Neural tube defects: maternal serum screening and prenatal diagnosis. | Neural tube defects represent some of the most common and serious of the congenital malformations. Although elevation of alpha-fetoprotein in amniotic fluid is not diagnostic, it does indicate an abnormality of the fetus in a very high proportion of cases. A normal level, however, does not exclude the possibility of a ... | 80,780 | [
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0.1090178,
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0.1587209,
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0.09217024,
... |
Simple and durable staining of thick sections of the human brain for macroscopic study. | Observations on gross morphology of the brain is greatly facilitated by enhancing the contrast between gray and white matter. The proposed technique is much more simple than the generally recommended Mulligan method and it variations. Moreover, there is no loss of stain since the fugitive surface impregnation, obtained... | 80,847 | [
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0.1878967,
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0.07723395,
0.1509397,
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0.143967,
-0.03792055,
0.1414644,
0.03430726,
0.050... |
[Fluorescence anisotropy and myelin structure. III. Effect of temperature changes on the orientation of dye molecules in nerve fibers]. | The temperature dependence of fluorescence polarization of stained nerve fibres has been studied. As has been previously demonstrated by the authors, the dependence of fluorescence polarization on the angle between the electrical vector of exciting light and the fibre axis (azimuth characteristics) is associated with t... | 80,851 | [
-0.04146707,
0.05632822,
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0.1692376,
-0.4731326,
0.2345553,
0.3135553,
0.03017887,
0.0998... |
Study on the nerve endings in the pancreas of Rattus rattus refescens and Gallus domsticus as revealed by the cholinesterase technique. | An investigation was undertaken to study the nerve endings in the pancreas of Rattus rattus rufescens and Gallus domesticus by cholinesterase technique. Bulb-like nerve ending in the connective tissue (negatively stained) and dot-like nerve ending in the lobular cells were recorded in Rattus. Dot-like nerve ending on t... | 80,895 | [
0.4189474,
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0.5301409,
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0.01736558,
0.00324426,
0.05286432,... |
[Late results following palliative vascular embolization in inoperable kidney tumors. (Preliminary report)]. | During 18 months in 15 patients with inoperable renal tumours palliative therapeutic vascular embolisations were carried out with the help of an own catheter technique. In contrast to preoperative embolisation (16 patients) in the inoperable cases a non-absorpable polyvinyl alcohol foam substance ("Ivalon") was used, w... | 80,897 | [
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0.09565178,
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0.0701689,
0.2695499,
0.5071315,
0.1592085,
0.2295593,
-0.3312568,
... |
Fluorescent labelling of cell membranes and cytoplasmic proteins in living cells. | Primary amino groups may be selectively labelled in living cell cytoplasmic components by staining with the covalently binding fluorochrome reagent fluorescamine. The reaction is extremely rapid and occurs at very low reagent concentrations. Cells survive such treatment and gradually remove or metabolize the labelled s... | 80,918 | [
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0.3899598,
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0.2525325,
0.03309625,
0.2052646,
-0.2683158,
-... |
Effect of copper and tri- and hexavalent chromium on the work of an activated sludge. | The effect of metals (Cu2+, Cr3+, Cr6+) on the work of an activated sludge grown in crude oil refining or synthetic wastes was examined. The activated sludge method was found to be applicable for the purification of wastes carrying up to 0.8 mgCu2+/1,15mgCr3+/1, or 20mgCr6+/1. Higher concentrations of these metals inhi... | 80,927 | [
-0.1316458,
0.1968654,
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0.1737898,
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0.05732872,
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0.04326636,
0.282284,
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0.2195798,
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0.1102752,
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0.5183439,
0.121799... |
The effect of cyclohexane derivatives on selection of bacterial groups forming activated sludge microflora. | The effect of cyclohexanol, cyclohekxanon and cyclohexylamine on the selection of bacteria in a model population composed of bacteria isolated from activated sludge was examined. The initial population consisted of both gram-positive and gram-negative bacteria. The latter, which accounted for 90-97% of the population, ... | 80,928 | [
-0.06880707,
0.08206926,
-0.2126247,
0.1919869,
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0.03763682,
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0.06416459,
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0.3509013,
-0.00002263689,
0.2149184,
0.2916269,
0.3710701,
-0.0865... |
Studies on myelin proteins in human peripheral nerve. | The myelin fraction from human peripheral nerve was prepared. Two basic protein fractions (BF-P2 and PB) were isolated from acid extracts of the myelin fraction and three glycoproteins (BR-PO, PASII and Y protein) were purified from its acid-insoluble residue. In biochemical analysis the human BF-P2 protein (M.W.13,000... | 80,952 | [
0.2047665,
-0.2138733,
-0.07165053,
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0.1392285,
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0.02655252,
0.1531643,
0.1502309,
-0.3143122,
0.2943331,
-0.0360245... |
[Antigenic relations between human papilloma viruses (HPV): experimental study in guinea-pigs (author's transl]. | A study of specific immune response in guinea-pigs after immunization with human papilloma viruses (HPV) purified from plantar warts, hand warts and condyloma acuminata is reported. The respective viruses induced the production of high antibody titres as well as specific cellular immunity as demonstrated by intradermal... | 80,972 | [
0.1257814,
-0.4659323,
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0.3144447,
0.2432311,
-0.2975762,
-0.225476,
0.1787609,
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0.4150357,
0.02024768,
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0.1212369,
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0.3078182,
0.205575,
0.1082378,
-0.1040024,
-0.0... |
Loss of the lipoprotein lipase activating ability of rat serum after administration of some fatty liver inducing drugs. | The effects of the administration of different fatty liver inducing drugs on the serum lipoprotein lipase activating ability was investigated in rats. Addition of serum from 2-mercaptoethanol-, 2-mercaptoacetate-, ethionine- or D-galactosamine- treated rats failed to activate heart and adipose tissue lipoprotein lipase... | 80,991 | [
-0.03895387,
-0.06503031,
-0.3433191,
-0.2379178,
0.2170451,
-0.03004554,
-0.2115506,
0.1136153,
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0.03212606,
0.06438579,
0.2355468,
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0.4105517,
0.1464085,
0.05246953,
-0.2440575,
0... |
Sex determination in nuclei of amnion fluid cells. | Hypotonic treatment of amnion fluid cell-nuclei was found to enhance demonstration of Y chromatin and of autosomal fluorescence in interphase cell-nuclei following quinacrine mustard staining. In contrast, visualization of the Barr body was not improved by this treatment. Nuclear sex determination on cellular material ... | 81,116 | [
-0.08799765,
0.4126581,
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-0.08785456,
0.541233,
0.05967827,
-0.2000329,
... |
Sequential staining of DNA-aldehyde with Schiff's reagent and acriflavine-SO2. | Acid hydrolysed DNA of rat liver was stained with Schiff's reagent at pHs 1.7 or 3.0 followed by staining with acriflavine-SO2 at pH 2.0 as well as with acriflavine-SO2 followed by Schiff's reagent at pH 1.7 or 3.0. Nuclei stained with Schiff's reagent at pH 1.7 were brown-yellow and an analysis of their absorption cha... | 81,160 | [
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0.5243781,
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0.3266122,
0.1339078,
-0.178158,
-0.18875,
... |
[The present state of prevention of rhesus immunisation (author's transl)]. | Rhesus factor immunisation and its complications should disappear if the indications and the techniques for abolishing it are followed. The indications follow from the usual mechanism by which immunisation occurs. This is the passage of Rh positive fetal red blood cells into the maternal circulation where they are dete... | 81,222 | [
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0.19509,
0.5477878,
0.205926,
0.0131365,
0... |
Flare and itch induced by substance P in human skin. | Intradermal injection of synthetic substance P (10(-7)--10(-5) M in humans produced flare, wheal and itching. These responses were inhibited by oral pretreatment of the subjects with an antihistaminic drug (chlorcyclizine) or by local pretreatment with Compound 48/80 administered to deplete the local stores of mast-cel... | 81,243 | [
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0.0007187389,
-0.3276954,
0.3090818,
-0.0262... |
Encephalomyelitis with thyrotoxicosis. | A case of thyrotoxicosis associated with neuropathy and encephalomyelitis is reported which gradually improved as regards the hyperthyroidism and the neurological deficit during treatment with Tapazole. The possible role of the nervous system of an excess of thyroxine or an autoimmune factor as a cause of the involveme... | 81,278 | [
-0.07016803,
-0.09059545,
-0.04091651,
-0.1599565,
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0.1613366,
0.04134365,
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0.05239373,
-0.594982,
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-0.2008193,
0.03625775,
0.01058275,
0.191516,
0.1061928,... |
Hyperreactive (hyaline, opaque, dark) muscle fibers in Duchenne dystrophy. A biopsy study of 16 dystrophy and 205 other neuronmuscular disease cases and controls. | Biopsies of 16 patients with Duchenne dystrophy and 205 consecutive biopsies of other neuromuscular diseases and controls were studied for the presence of hyperreactive (hyaline, dark, opaque) fibers. All biopsies of Duchenne dystrophy showed hyperreactive fibers; the percentage varies between values below 1 up to 19 (... | 81,285 | [
-0.08784947,
0.0008371702,
-0.108563,
-0.2213213,
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0.4948047,
0.06553859,
0.1213812,
0.2630792,
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0.442687,
0.03333989,
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0.0258255,
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0.04571363,
0.5361136,
0.06299356,
-0.1889764,
-0... |
Rabbit antiserum against a non-T, non-B leukemia cell line that carries the Ph1 chromosome (NALM-1): antibody specific to a non-T, non-B acute lymphoblastic leukemia antigen. | Rabbit immune sera against human cells of a non-T, non-B leukemia cell line bearing the Ph1 chromosome (NALM-1) were characterized. After proper and exhaustive absorption, the sera were tested by indirect membrane immunofluorescence on a panel of 19 human hematopoietic cell lines with T-, B-, or non-T, non-B cell surfa... | 81,309 | [
-0.2656309,
-0.1270119,
-0.131981,
-0.01498775,
-0.2733321,
-0.1640169,
-0.4664524,
0.154629,
0.3092542,
0.2453348,
0.2436459,
0.5086288,
0.2843339,
0.1940705,
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0.01785485,
-0.09659924,
-0.153619,
0.413408,
0.05528837,
-0.1708755,
0.3... |
Inhibition by RNA of RNase H activity associated with reverse transcriptase in Rauscher murine leukemia virus cores. | We reported earlier that core preparations of Rauscher murine leukemia virus, when separated on an isopycnic sucrose gradient, did not contain detectable levels of RNase H activity, while retaining high levels of reverse transcriptase activity. We reexamined this phenomenon, and the earlier observation was found to be ... | 81,312 | [
-0.2597735,
0.04239036,
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0.5155878,
0.05113054,
0.2306934,
0.115471,
0.1736693,
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0.1794704,
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0.106381,
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-0.13225,
-0.006050861,
0.1677143,
0.545336,
0.05995205,
-0.1194836,
0.040... |
Limited cleavage of human immunoglobulins by elastase of human neutrophil polymorphonuclear granulocytes. Possible modulator of immune complex disease. | Human polymorphonuclear lysosomal granules contain a neutral protease which is capable of digesting human immunoglobulins. The protease is located in the azurophil granules and enzymatically cleaves IgG, producing a Fab-like piece which is recoverable. The Fc-like fragment is not crystallized. The Fab-like fragment com... | 81,354 | [
-0.02344985,
0.05120657,
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0.1286515,
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0.277922,
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0.09726288,
0.2249735,
0.2039261,
0.1125636,
-0.2105962,
... |
The MB isoenzyme of creatine kinase as an indicator of severity of myocardial ischaemia. | 86 patients with ischaemic heart-disease were assessed for the presence of the MB isoenzyme of creatine kinase (C.K.-MB). Raised C.K.-MB levels with normal total C.K. were found in 10 patients with a clinical picture, but no electrocardiographic evidence, of acute myocardial infarction. 4 of these patients later had an... | 81,364 | [
-0.5404877,
0.1151165,
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0.2396785,
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0.01023917,
0.3366825,
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0.2753737,
0.09976324,
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0.2020899,
0.365751,
-0.04842829,
0.2588651,
-0.1477575,
-0.009363338,... |
Inhibitor of in-vitro granulopoiesis in plasma of patients with renal failure. | Plasmas from 31 patients with moderately severe to severe renal failure inhibited granulopoietic colony formation in human marrow in vitro. The inhibitory activity could not be removed by in-vitro dialysis but was present in an ultrafiltered fraction of molecular weight less than 25 000 daltons. It inhibited the produc... | 81,413 | [
-0.002070879,
0.03596974,
-0.09380169,
-0.3059968,
0.3756761,
0.1771098,
-0.08620091,
-0.1291821,
-0.09106722,
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0.08645682,
0.1427071,
0.3314386,
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-0.03322144,
-0.1794527,
0.4622877,
0.1222112,
0.04434524,
-0.04090... |
A review of the bleomycin experience in the United States. | As bleomycin has up to now proved effective when used alone, the main thrust of current clinical investigations predominantly concerns its use in combination with other drugs. This has occurred along three broad patterns: 1) combination with vinca alkaloids which has been mainly in testicular carcinoma; 2) as part of m... | 81,499 | [
-0.2007432,
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0.2195316,
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0.07582314,
0.09364969,
0.1020953,
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0.4226991,
0.02978926,
0.5004764,
0.1972932,
-0.3155831,
0... |
Antitumor antibiotic bioactivation, biotransformation and derivatization by microbial systems. | Microbial transformations refer to reactions catalyzed by microbial enzymes, especially when specific and useful metabolites accumulate in fermentation media. These transformations have tremendous potential for use in the development of new antitumor drugs and these can also be used as models of mammalial metabolism. M... | 81,506 | [
-0.1453583,
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0.226607,
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0.3106527,
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0.1874125,
0.228492,
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0.235848,
0.3580544,
-0.1156382,
-0.09... |
HLA-D restriction of the macrophage-dependent response of immune human T lymphocytes to PPD in vitro: inhibition by anti-HLA-DR antisera. | The response of T cells from sensitized individuals to low doses of PPD in vitro is macrophage-dependent. By testing different allogeneic combinations of macrophages and T lymphocytes, it was found that an optimal response required that antigen be presented by macrophages sharing at least one of the HLA-D determinants ... | 81,515 | [
0.05286877,
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0.04659213,
0.3487495,
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0.2883787,
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0.1062187,
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0.05959778,
0.2968358,
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0.37127,
0.2809411,
0.2587645,
-0.1119901,
-0.... |
[Therapeutic progress. Critical analysis of controled and non-controled clinical studies]. | Methods used in the evaluation of therapeutic results in clinical oncology are criticized on the basis of recent examples of studies including the most-used antitumor agents. The need for random allocation of patients in comparative studies is underlined and the practical, statistical, and ethical limitations on random... | 81,520 | [
-0.03294556,
0.1529834,
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0.05328441,
0.2179181,
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0.6009783,
0.2971081,
0.05577904,
-0.0046064,... |
[The fiberoptic-endocopic intubation for the palliatuve treatment of malignant esophageal stenosis]. | Fibreoptic-endoscopic dilatation and intubation is a relatively new and safe palliative treatment for patients with inoperable esophageal carcinoma. The procedure is described at length in three patients in whom it produced instant relief of dysphagia and rapid improvement of nutrition. The stay in hospital is reduced ... | 81,522 | [
-0.263516,
-0.1911361,
-0.1458654,
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0.01000246,
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0.1342055,
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0.2420659,
0.01593719,
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0.1224437,
-0.1470914,
-0.07378179,
0.3092293,
0.1683458,
-0.1086315,... |
Immune response-associated antigens on mouse leukemia cells. I. Detection of Ia antigens on GRSL cells. | The expression of immune response-associated (Ia) antigens on the surface of mouse strain GR (H-2dx) ascites leukemia (GRSL) cell lines was studied by cytotoxic tests, immunofluorescence, and immunoprecipitation assays. Ia expression varied among the three GRSL cells lines (GRSL 2, GRSL 14, and GRSL 15) studied by cyto... | 81,549 | [
0.2947274,
-0.4797819,
-0.2491916,
-0.1085745,
0.3813548,
0.09231453,
0.03943341,
0.2136841,
0.01113928,
0.2538959,
-0.08115932,
0.2228202,
0.03192197,
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0.04106337,
0.2888821,
0.2652613,
0.1882693,
-0.3021876,
... |
[Cryosurgical treatment of rectal carcinoma (author's transl)]. | After comprehensive experimental especially morphological studies in animals, we started cryo-therapy of rectal carcinoma in 1972. We now present the first critical 5-years review concerning indication, clinical results and cryo-immunological features. In strongly indicated cases local tumour destruction by extremely l... | 81,576 | [
0.06104613,
-0.1519413,
-0.2162531,
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0.01074378,
0.1796698,
0.04800737,
0.123556,
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0.2814062,
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-0.01949699,
0.07198239,
0.3861988,
0.2431158,
0.4016538,
0.01087546,
... |
Activity and distribution of bacteriolytic N-acetyl-muramidase during growth of Acanthamoeba castellanii in axenic culture. | Bacteriolytic endo N-acetylmuramidase of Acanthamoeba castellanii has been studied. In amoeba cells the enzyme, like exo N-acetylglucosaminidase and acid phosphatase, is attached to the lysosomes, as it is sedimentable when homogenates are prepared in medium containing sucrose. The sedimentability could be abolished by... | 81,598 | [
-0.3303121,
-0.4995999,
-0.1406584,
0.2772477,
-0.2809947,
-0.08584599,
-0.3774772,
-0.05585654,
0.2113897,
0.03669325,
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-0.3017304,
0.03952473,
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0.1033692,
-0.06125062,
0.2855552,
0.9554025,
0.09221385,
-0.08009314... |
Antigenic glycopolypeptides HA1 and HA2 of influenza virus haemagglutinin. II. Reactivity with rabbit sera against intact virus and purified undissociated haemagglutinin. | Rabbit sera produced against either intact virus or purified undissociated haemagglutinin were examined for reactivity with highly purified haemagglutinin glycopolypeptides. Sensitive radioimmunoassay for 125I-labelled glycopolypeptides revealed antibody reactive with either glycopolypeptide HA1, or glycopolypeptide HA... | 81,606 | [
0.04893805,
-0.2313406,
-0.3111318,
0.001557371,
0.2804774,
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-0.1861431,
0.2764638,
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0.1818734,
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0.1235507,
0.2005698,
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0.3636593,
-0.1182898,
-0.2448575,
-0... |
Treatment of liver cancer with regional intraarterial 5-FU infusion. | The results of a retrospective three year study of forty-six patients with cancer of the liver treated with regional intraarterial infusion of 5-FU are reported. No primary mortality was noted. Oblective overall remission rate was 43 per cent. Overall median survival from onset of treatment was six months. The one year... | 81,616 | [
-0.04171846,
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-0.4022405,
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0.103492,
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0.1130577,
0.07020003,
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0.4160114,
0.3229654,
0.4021018,
0.02373138,... |
Nursing care of the infant in surgery. | The operating room nurse, as an important team member, actively participates in the specialized care of the infant undergoing surgical intervention. Using the steps of the nursing process, he or she initiates the assessment preoperatively, collecting data about the health status of the patient. Based on these data, the... | 81,657 | [
-0.1482068,
-0.2363367,
-0.3178802,
-0.3729214,
-0.06640471,
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0.08455338,
-0.3162767,
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-0.01743603,
0.2306533,
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-0.2706931,
-0.4093218,
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-0.4190396,
-0.09728026,
0.009763729,
-0.04000842,
0.3020677,
0.04509067,
0.000... |
Physicochemical and immunochemical properties of carcinoembryonic antigen (CEA) from different tumour sources. | The physical, chemical and immunochemical properties of carcinoembryonic antigen (CEA) purified from hepatic metastases of eight tumours, originating in the colon (6), stomach (1) and lung (1), have been examined. Differences were observed in the overall molecular charge, and also in the carbohydrate composition of the... | 81,670 | [
0.004828078,
0.04897022,
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0.009457761,
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0.2406524,
0.02705827,
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0.08359443,
0.3524927,
0.1839332,
0.330601,
0.1213115,
-0.15312... |
Release of beta-thromboglobulin from human platelets by therapeutic intensities of ultrasound. | The effects of therapeutic intensities of ultrasound on human platelets in whole blood were investigated by monitoring the release of the platelet specific protein beta-thromboglobulin (beta-TG). More beta-TG was released as the intensity of the ultrasound was increased and also as the driving frequency was decreased f... | 81,682 | [
-0.0467711,
0.225757,
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0.3052881,
0.3314061,
0.4809154,
-0.1252817,
... |
[Study of individual Pacinian corpuscle mechanoreceptors following application of colchicine to a nerve]. | Colchicine application to the cat caudal mesenteric nerve containing sensory fibers for single mechanoreceptors (Pacinian corpuscles) causes degeneration of the axis cast of the nerve endings. Ultrastructural changes in the receptors showed no difference from the axonal degeneration after the nerve section but the rate... | 81,692 | [
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0.1674301,
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0.2166533,
0.3357059,
0.2479403,
0.06085185,
... |
Detection of a new antibody system reacting with Dane particles in hepatitis B virus infection. | Antibodies in the serum reacting with antigens on the surface of radiolabelled Dane particles distinct from hepatitis B surface and core antigens (HBsAg and HBcAg) were detected, using a double antibody precipitation assay, in 12 out of 15 patients early in the course of acute type B hepatitis and at the time of disapp... | 81,702 | [
-0.1478949,
0.2009038,
-0.1040953,
0.1062568,
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0.09759236,
0.3235017,
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0.05679819,
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0.03291149,
0.2129295,
0.06675571,
0.2346288,
-0.2265963... |
Ethanol dependence in the rat: role of non-specific and limbic regions in the withdrawal reaction. | Chronic bipolar electrodes were implanted in cortical, limbic, diencephalic and mesencephalic regions of the rat. Following recovery from surgery the rats were maintained for 14--26 days on a liquid diet in which 35--42% of total calories were provided by ethanol. Following ethanol withdrawal, electrographic and behavi... | 81,750 | [
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0.1469673,
-0.1565992,
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0.2868275,
-0.4482462,
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0.2129236,
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0.01486232,
0.07302224,
0.02793474,
0.03360521,
-... |
Digital memory recorder in electromyography and nerve conduction studies. | Specifications are given: (i) for a 3-channel digital memory that, when connected to an inkjet writer, allows action potentials from muscle and nerve to be recorded without distortion (upper limiting frequency 10,000 Hz); (ii) for a 14-channel digital memory connected to a 14-channel inkjet writer for the measurement o... | 81,756 | [
-0.2652521,
0.2654354,
-0.04270633,
-0.3955789,
-0.03541431,
-0.3021277,
-0.2942987,
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0.3761737,
0.003567109,
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0.09639743,
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0.07258652,
0.1589965,
-0.2574407,
-0.2209492,
0.2813323,
-0.1190553,
0.05660... |
Activity of human hippocampal formation and amygdala neurons during memory testing. | Single and multiple unit recordings were made from fine wires stereotaxically implanted in the hippocampus (HC), hippocampal gyrus (HCG), and amygdala (Am) of psychomotor epileptics. During a series of memory and control tests presented on slides, 21 of 155 HCG units, 15 of 59 HC units, and 2 of 54 Am units showed what... | 81,761 | [
0.02739206,
0.04885804,
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0.02849565,
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0.09463121,
-0.04575209,
-0.0995049,
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0.1327771,
0.168... |
Ag staining of the nucleolus organizer (NO) and its relationship to satellite association. | The frequency of involvement in satellite association and the frequency of selective staining of the secondary constrictions with silver solutions have been studied in five phenotypically normal individuals, all carriers of morphological variants of the nucleolus organizing region (NOR). The results show the preferenti... | 81,799 | [
-0.124903,
0.2779951,
0.2907641,
-0.2800241,
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0.1637076,
0.03552121,
-0.03468018,
... |
Synthesis of 5''-amino-3,5''-dideoxybutirosin A. | The titled compound was prepared by condensation of 3'-deoxyparomamine derivative (5) with 2,3-O-bis(p-nitrobenzoyl)-5-O-tosyl-D-xylofuranosyl bromide followed by 1-N-acylation with the active ester of (S)-4-benzyloxycarbonylamino-2-hydroxybutyric acid. The compound was slightly more active than 3'-deoxybutirosin A aga... | 81,829 | [
-0.1683376,
0.1248825,
-0.1112775,
0.101002,
0.2118195,
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-0.2497788,
0.2278197,
0.02584435,
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0.2067545,
0.180841,
0.2072805,
0.2497275,
0.2208146,
-0.1563305,
-0.059099... |
Adrenal function and passive immunity in the dystocial calf. | Dystocial calves were tested for their ability to absorb colostral immunoglobulins and establish a competent passive immunity. Twenty dystocial and 20 eutocial calves were fed 1 liter of colostrum 4 h after birth and an additional liter 12 h later. Their absorption of the immunoglobulins A, G, and M, as indicated by se... | 81,842 | [
-0.04993809,
-0.0147862,
-0.1802465,
0.04080139,
-0.1478222,
-0.3285937,
-0.1704763,
-0.098225,
-0.09498709,
0.02071674,
0.1415336,
0.1217616,
0.166977,
0.1842903,
-0.1484568,
-0.203905,
-0.4675915,
-0.03684594,
-0.2245745,
0.2302576,
0.2330658,
0.3773901,
-0.02779029,
... |
A subpopulation of adherent accessory cells bearing both I-A and I-E or C subregion antigens is required for antigen-specific murine T lymphocyte proliferation. | A murine T lymphocyte proliferation assay that used antigen-primed lymph node T cells, was antigen specific, and required exogenous accessory cells was used to characterize the accessory cells that supported proliferation. These cells were Thy 1.2 negative, radioresistant, glass-adherent, and were functional only if al... | 81,849 | [
0.110833,
-0.1927072,
-0.1669911,
-0.08780106,
0.04605675,
-0.1874901,
0.01780391,
0.08143853,
0.3109527,
0.4203282,
-0.1006557,
0.2928218,
-0.04572939,
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-0.08026963,
0.04891649,
0.441456,
0.136485,
0.03506177,
-0.07394186,
... |
Studies of immunosuppression by cobra venom factor. I. On early IgG and IgM responses to sheep erythrocytes and DNP-protein conjugates. | The immunosuppressive activity of CVF was evaluated in mice immunized with sheep erythrocytes and dinitrophenylated proteins. Serum antibody levels to these immunogens were estimated in activity units and on a weight basis for IgG. IgM as well as IgG antibody responses were diminished in mice pretreated with CVF. Howev... | 81,862 | [
0.00623416,
0.02274897,
0.2628691,
-0.1074847,
0.2302562,
-0.1326652,
0.221409,
0.2259714,
0.05142277,
0.2613107,
0.02804712,
0.06704354,
0.114568,
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-0.2123169,
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0.1751674,
0.09582234,
0.3982295,
-0.03630863,
-0.04060194,
-0.198365,
-0... |
[Second increase in plasma volume after single infusion of hydroxyethyl starch (author's transl)]. | 6 patients without evidence for renal, hepatic or pancreatic disease were treated with intravenous infusions of 500 ml hydroxyethyl starch (6%) over a period of 60 min. In the course of the infusion we observed an increase in plasma volume from 2.72 +/- 0.101 to 3.36 +/- 0.141. After 2 h plasma volume decreased to 3.02... | 81,905 | [
-0.3596444,
0.007784914,
-0.291797,
-0.4119602,
0.1568945,
-0.2229596,
0.01359429,
-0.1263045,
-0.06422229,
0.1089285,
0.2415534,
-0.04198018,
0.1398274,
-0.1697066,
-0.2590607,
-0.01343113,
-0.09976453,
0.2474607,
0.1580393,
0.2044059,
0.3649266,
-0.006517888,
0.04342129... |
Antenatal diagnosis of sickle-cell anaemia by D.N.A. analysis of amniotic-fluid cells. | The polymorphism of a restriction endonuclease site has been used for antenatal diagnosis of sickle-cell disease. In a normal person, the beta-globin gene was contained in a Hpa I-digested D.N.A. fragment 7.6 kilobases (kb) in length. In a family where the sickle gene was contained in a variant 13.0 kb fragment, restri... | 81,926 | [
-0.2572168,
-0.529088,
-0.08824306,
0.2327061,
0.175157,
-0.05674819,
0.008575569,
0.1806618,
0.2760981,
-0.001578784,
0.2328725,
0.0505182,
-0.1410612,
-0.3817773,
-0.1633654,
-0.5048283,
-0.6309345,
0.07114977,
0.3132815,
0.07745914,
0.46153,
-0.06585804,
-0.207158,
-... |
Controlled trial of hyposensitisation to Dermatophagoides pteronyssinus in children with asthma. | Hyposensitisation with Dermatophagoides pteronyssinus tyrosine absorbate in asthmatic children with bronchial sensitivity to D. pteronyssinus was effective in a 12-month double-blind controlled clinical trial. Compared with controls, treated children used a smaller quantity of drugs while maintaining clinical and lung ... | 81,927 | [
0.1625825,
-0.1020604,
-0.01704132,
-0.01565212,
-0.01656291,
-0.230139,
-0.1882954,
-0.04625737,
0.1782734,
-0.08401727,
0.2894689,
0.07508681,
-0.1844958,
-0.1543911,
-0.333069,
-0.04494555,
-0.1362137,
0.1474854,
-0.2898484,
0.07841644,
-0.1881129,
0.1580013,
-0.120395... |
Intermittent catheterisation in the management of children with neuropathic bladder. | Twenty-three children with neuropathic bladder have been treated by intermittent catheterisation during the past 3 years. Twelve are now practically dry, nine are drier than before, and two have remained wet. Urinary infections have not been a major problem, but it is too soon to assess the long-term effects on the upp... | 82,002 | [
-0.08205868,
0.3162045,
-0.01553803,
0.08546133,
-0.05239205,
-0.5341439,
-0.34301,
-0.1655118,
0.01256633,
0.1216807,
0.2060923,
0.1387385,
-0.008445157,
-0.2556361,
-0.2502872,
-0.1711533,
-0.2670279,
0.3041295,
-0.2619186,
-0.4114571,
-0.03488387,
-0.01521836,
-0.06004... |
Levamisole in rheumatoid arthritis. A randomised double-blind study comparing two dosage regimens of levamisole with placebo. Multicentre study group. | The therapeutic effect of levamisole in patients with rheumatoid arthritis was evaluated in a sixteen-centre double-blind controlled study which compared continuous and intermittent levamisole treatment with placebo for six months. 363 patients with classic or definite rheumatoid arthritis and active disease were evalu... | 82,030 | [
-0.04079008,
0.05621769,
0.08363675,
-0.1533187,
-0.1155961,
-0.2842992,
-0.09030065,
0.2516004,
-0.2023495,
0.02531209,
-0.1496974,
0.1916459,
-0.06818891,
-0.03097179,
0.2705226,
0.1974533,
-0.3694206,
0.2979801,
-0.07002265,
0.157756,
-0.08331512,
0.01909082,
0.2360958... |
Cot deaths and water-sodium. | Over a thirty-year period in Scunthorpe, during which there were two changes in the sodium content of the water supply, there were significantly more sudden deaths in infancy during the decade when sodium levels were highest. This is compatible with the hypothesis that hypernatraemia is a factor leading to cot death. C... | 82,031 | [
-0.4133766,
-0.3038143,
-0.0297761,
-0.01995216,
-0.2448463,
-0.1686879,
-0.2237661,
-0.3853972,
-0.1773212,
0.07353272,
0.2299102,
0.3885946,
-0.2668764,
0.1228994,
-0.03248399,
-0.3697448,
-0.02612931,
0.01261908,
0.3458243,
-0.1261915,
0.3587994,
0.1768286,
-0.1255412,... |
Transformation of normal bone-marrow cells by a leukaemic cell line associated with a presumptive new human virus. | Intracytoplasmic leukovirus-like bodies were found in the cells and culture medium of a T-cell lymphoblast line established from a leukaemic patient. When the cells were lethally irradiated and added to normal bone-marrow cells the latter were transformed into continuous replication and produced the same types of virus... | 82,033 | [
-0.419033,
-0.09065147,
-0.1802064,
-0.02400817,
0.09016797,
-0.1229668,
-0.1924899,
0.1662531,
0.08267741,
0.3241571,
-0.01191204,
0.1121213,
-0.01809702,
0.02472699,
-0.3212321,
-0.1656902,
-0.2256004,
-0.197503,
0.1386537,
0.1988698,
0.336651,
0.1279822,
0.003750499,
... |
Pathogenesis of prolactin-secreting pituitary adenomas. | 42 women with amenorrhoea and hyperprolactinaemia had trans-sphenoidal surgery and resection of histologically verified pituitary adenomas. 74% of these patients developed amenorrhoea and/or galactorrhoea in immediate association with the use or discontinuation of oral contraceptives or post partum. There was enough ad... | 82,034 | [
0.08380126,
-0.1627072,
0.09043019,
-0.1555517,
-0.03689565,
-0.4021309,
-0.1563415,
-0.3756323,
0.2315376,
0.02122749,
0.3015676,
0.2227932,
-0.02620803,
-0.03837994,
-0.101212,
-0.1159945,
-0.2226924,
0.05081696,
-0.02904473,
-0.2462572,
-0.06401281,
0.4593392,
-0.14867... |
Effect of cimetidine in symptomatic gastro-oesophageal reflux. | Twenty-seven patients with symptomatic gastro-oesophageal reflux received cimetidine 1.6 g daily for 6 weeks and matching placebo for 6 weeks in a randomised double-blind crossover trial. They complained of significantly more episodes of pain on placebo than on cimetidine (1186 vs 581) and consumed significantly more a... | 82,086 | [
0.01347286,
0.01502771,
-0.2122452,
-0.04346349,
-0.08510676,
-0.05133428,
-0.1155001,
-0.1264386,
0.4964462,
-0.2697639,
0.1158663,
0.1911771,
-0.08663188,
-0.1726014,
-0.3500603,
-0.1820104,
-0.1382401,
0.1890516,
-0.09271177,
0.2883798,
0.1344705,
0.01906945,
-0.123619... |
[Clinical relevance of serum alpha-1-fetoprotein determinations]. | History, physiological and pathological properties and clinical significance of alpha-1-fetoprotein (AFP) are reviewed in detail. Present observations suggest that additional information can be expected from AFP-determination as an index for prognosis and response to chemotherapy in patients with AFP-producing tumors. ... | 82,239 | [
0.1879535,
-0.3090296,
-0.1693818,
-0.2689375,
0.1629939,
-0.3162027,
-0.280535,
-0.02781189,
0.07323814,
0.398402,
0.0857945,
0.4915904,
0.001695692,
-0.1233823,
-0.2705595,
-0.2118236,
-0.5581653,
0.3151501,
-0.3222337,
0.4868973,
0.4927829,
0.1108306,
-0.1449582,
0.3... |
Effects of IRA in vitro on T- and B-lymphocytes from peripheral blood of patients with connective tissue diseases. | The effect of immunoregulatory alpha-globulin (IRA) in vitro on T-lymphocytes (rosette forming cells) and B-lymphocytes (surface IgG and IgM) in peripheral blood of healthy subjects and the patients with connective tissue diseases were investigated. Marked inhibitory effects of IRA were observed on T-lymphocytes and su... | 82,280 | [
0.07220733,
-0.3389686,
-0.3689931,
0.06360985,
-0.004467924,
0.05011993,
-0.3277597,
0.1313655,
-0.01703794,
0.4718224,
-0.07987235,
0.3570844,
0.3080845,
0.1300479,
-0.3003005,
0.08469823,
-0.02655408,
-0.04602525,
-0.2851131,
0.621084,
0.1743845,
0.2267665,
-0.08608162... |
Inhibition of ultraviolet and phototoxic dermatitis in the mouse. | The effect of inhibitors on the inflammatory oedema elicited by medium-wave ultraviolet radiation (UVB) and long-wave ultraviolet radiation (UVA) in combination with chlorpromazine has been studied in the mouse, by means of a quantitative technique. Inhibition of the UVB reaction was observed with indomethacin, acetyls... | 82,323 | [
-0.09684988,
-0.2285201,
-0.2040036,
0.02301446,
0.2050873,
0.1300188,
-0.1362544,
0.01450623,
0.375553,
0.02682079,
-0.1968884,
0.1892201,
0.1128975,
-0.06901559,
-0.2418738,
0.1948439,
-0.08915257,
0.1941698,
-0.09575292,
0.6979926,
0.2998754,
-0.1508159,
-0.21152,
-0... |
Eosinophilic spongiosis in early pemphigus foliaceus. | A case of widespread non-specific, itchy exanthema in a 74-year-old female is presented. An early skin biopsy showed eosinophilic spongiosis. Later a dermatitis herpetiformis-like eruption developed. However, immunofluorescence microscopy showed intercellular IgG deposits characteristic of pemphigus. Recognition of eos... | 82,338 | [
0.06704494,
-0.1227702,
0.1605708,
0.1214772,
0.2142579,
-0.118873,
-0.1322355,
-0.436815,
-0.2537217,
0.07184823,
0.1671456,
0.3789838,
-0.01634325,
0.04889384,
-0.06496769,
-0.3657662,
-0.07269122,
0.4783254,
-0.1240395,
-0.4124527,
-0.05876274,
0.3527199,
-0.1498072,
... |
Treatment of acne with cyproterone acetate and ethinyl estradiol. | Tablets containing 2 mg cyproterone acetate and 0.05 mg ethinyl estradiol in a calendar package of 21 days were used as an oral contraceptive to treat acne. The series comprised 20 patients. The women were 18--43 years of age, and all had acne which had previously been resistant to therapy. The treatment was continued ... | 82,357 | [
0.1548217,
0.008119863,
-0.3731981,
0.01208985,
-0.1798826,
-0.1864855,
-0.2019331,
-0.05636482,
0.163223,
-0.1525144,
0.1810239,
0.3730508,
0.1785646,
0.365898,
-0.5088744,
0.04754157,
0.01269367,
0.1274209,
0.12464,
0.2242647,
0.4370676,
0.1002689,
-0.1393272,
0.05276... |
Systemic miconazole treatment of a patient with chronic granulomatous mucocutaneous candidiasis. | Miconazole given intravenously and orally was evaluated in the treatment of a patient with drug-resistant, chronic, widespread horny candida lesions. Marked clinical improvement occurred after 4 weeks of the first course of treatment, in which 400 mg of miconazole per day was given intravenously. After 3 months no sign... | 82,358 | [
0.2187623,
-0.1268134,
-0.1969759,
-0.1852273,
0.1545148,
0.02574646,
-0.09834418,
-0.04655861,
0.1017698,
-0.1485453,
0.1867493,
0.002452139,
0.08336151,
0.2241472,
-0.1446633,
-0.06951649,
-0.3871895,
0.1292935,
-0.04129429,
0.04274815,
0.1352922,
0.4118218,
0.2280362,
... |
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