title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Doppler evaluation of extracranial cerebrovascular disease. | The carotid Doppler examination is an accurate means of screening the extracranial carotid system for stenotic lesions. Comparison of 100 patients (200 vessels) examined by the Doppler method and arteriography showed agreement in 90% of the vessels and a significant error rate in only 3.5%. | 103,412 | [
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Acute coronary occlusion in the pig: effect of nitroglycerin on regional myocardial blood flow. | Myocardial blood flow was studied in 10 closed chest, anesthetized pigs after an acute balloon catheter occlusion of the left anterior descending coronary artery. With use of radioactive microspheres (15 mu), myocardial blood flow was measured before and during an intravenous nitroglycerin infusion and during a combine... | 103,419 | [
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The effect of nitroglycerin on gas exchange, hemodynamics, and oxygen transport in patients with chronic obstructive pulmonary disease. | The present study was designed to investigate pharmacological vasodilation in patients with chronic obstructive pulmonary disease (COPD). This may have long-term therapeutic implications. Sublingual nitroglycerin (GTN) was administered to 16 patients with COPD and no evidence of organic heart disease (except one patien... | 103,435 | [
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Dual effects of amphotericin B on ion permeation in toad urinary bladder epithelium. | The mechanisms of action of amphotericin B on the electrical properties of the toad urinary bladder epithelium were studied with microelectrode techniques. Cell membrane and transepithelial electrical potentials and resistances were measured in the absence and in the presence of the drug during exposure to bathing medi... | 103,440 | [
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Wegener's granulomatosis causing laryngeal and tracheobronchial obstruction in an adolescent girl. | A 12-year-old girl presenting with a painful neck mass and ulcerated gingival lesions was found to have Wegener's granulomatosis involving the gingivae, paranasal sinuses, ears, mastoids, larynx, trachea, bronchial tree, lungs, kidneys and joints. The initial illness and two subsequent exacerbations were treated with i... | 103,476 | [
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Ann Otol Rhinol Laryngol [Suppl]. | Mandibular replacement subsequent to major extirpative head and neck surgery is predisposed to complications in the best of hands. The most suitable prosthesis appears to be the previously resected mandible, both from the standpoint of antigenicity and configuration. This study establishes that in the canine mandible a... | 103,481 | [
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Antimalarial activities of WR-194,965, an alpha-amino-o-cresol derivative. | Pilot appraisals of the activities of WR-194,965 and WR-204,165, two closely related o-cresol derivatives (both Mannich bases), in owl monkeys infected with the multidrug-resistant Vietnam Smith strain of Plasmodium falciparum showed that these compounds had similar levels of efficacy. Total course doses effecting 90% ... | 103,492 | [
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Antimalarial activities of the 4-quinolinemethanols WR-184,806 and WR-226,253. | WR-184,806 and WR-226,253, two 4-quinolinemethanols structurally similar to WR-142,490 (mefloquine), have been studied in depth in owl monkeys infected with various drug-resistant and drug-susceptible strains of Plasmodium falciparum and P. vivax in an effort to provide support and guidance for projected evaluations in... | 103,493 | [
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Effect of two cancer chemotherapeutic agents on the antibacterial activity of three antimicrobial agents. | Cancer chemotherapeutic agents and antibacterial antibiotics are often given concomitantly. Daunorubicin, cytosine arabinoside, and three antibiotics (gentamicin, amikacin, and ticarcillin) were tested individually and in combinations to determine their antimicrobial activity against Pseudomonas aeruginosa, Klebsiella ... | 103,494 | [
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Discussion on the causes of failure of surgical treatment of partial epilepsies. | Despite continuous improvement in diagnosis and surgery, persistence of seizures following surgical treatment of partial epilepsies still occurs in a relevant number of cases (30--40%). The analysis of personal material and of data from the literature appears to indicate that relevant causes of surgical failure are dif... | 103,498 | [
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Microbial degradation of glycerol nitrates. | The fate of glycerol trinitrate when exposed to microbial attack has been investigated. Contrary to some earlier reports, this compound was readily biodegraded by employing batch or continuous techniques under a variety of cultural conditions. Breakdown of glycerol trinitrate took place stepwise via the dinitrate and m... | 103,501 | [
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Isolation, characterization and pathology of the toxin from a Microcystis aeruginosa (= Anacystis cyanea) bloom. | The nature of the toxicity of a bloom of blue-green alga, M. aeruginosa (= Anacystis cyanea), that occurred in a man-made lake was investigated. Crude algal bloom extracts were toxic to laboratory mice when injected intraperitoneally. The lethal dose (LD100) of these extracts was 15-30 mg of lyophilized algal bloom per... | 103,520 | [
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Probe of beta-galactosidase structure with iodoacetate. Differential reactivity of thiol groups in wild-type and mutant forms of beta-galactosidase. | Carboxymethylation with 14 C-labeled iodoacetate of cysteine residues in wild-type beta-galactosidase from Escherichia coli and in a defective beta-galactosidase from deletion mutant strain M15 was investigated in order to determine accessible positions in the tetrameric wild-type form and the dimeric mutant M15 protei... | 103,570 | [
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Effects of lipid-phase separation on the filipin action on membranes of ergosterol-replaced Tetrahymena cells, as studied by freeze-fracture electron microscopy. | The effects of lipid-phase separation on the filipin action on pellicle membranes of ergosterol-replaced Tetrahymena pyriformis cells were studied by freeze-fracture electron microscopy. The pellicle membranes with phase separations induced by chilling from 34 degrees C (growth temperature) to lower temperatures (30, 2... | 103,584 | [
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Restricted posterior parietal lesions in the rhesus monkey and performance on visuospatial tasks. | Monkeys with lesions restricted to the inferior parietal lobule or the banks and depths of the superior temporal sulcus were tested on a route-following task. These areas are considered on neuroanatomical grounds to be homologous to parts of the human posterior parietal cortex, where lesions produce profound spatial di... | 103,604 | [
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Response of human lymphocytes to mitogen: at what stage is there a requirement for Ca2+? | In order for significant DNA synthesis to be observed in the case of human lymphocytes stimulated for 36 h in presence of phytohemagglutinin (PHA), Ca2+ must be present in the medium continuously for at least 20 h; access to Ca2+ for 10-h periods during the first 30 h was not sufficient to permit DNA synthesis to occur... | 103,606 | [
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Effect of levamisole on metabolism of phagocytic cells. | The effect of levamisole (LMS) on glucose metabolism was studied using a protozoan phagocytic model and human leukocytes. At concentrations of greater than 10 microgram/ml, LMS inhibited glucose metabolism in the protozoan phagocytic model. Glucose metabolism in both the phagocytic model and normal peripheral blood leu... | 103,617 | [
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Organization of the sympathetic innervation in liver tissue from monkey and man. | The sympathetic innervation of the liver of monkey and man has been investigated in a combined fluorescence histochemical, chemical and electron microscopical study. By means of the Falck-Hillarp fluorescence method a dense network of monoamine-containing nerve fibers was visualized in liver tissue of monkey and man. T... | 103,622 | [
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The innervation and fine structure of paraneuronic cells in an amphibian pulmonary artery. | The pulmonary artery of Bufo marinus contains large numbers of bipolar cells situated in the tunica adventitia and in the outer layers of the media. These cells show a bright green-yellow fluorescence (emission spectra 485 nm) after formaldehyde pre-treatment suggesting that they contain a primary monoamine. The most c... | 103,624 | [
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Genetic and molecular organization of the 5S locus and mutants in D. melanogaster. | The topography of an entire redundant locus was analyzed by both genetic and molecular means. Three mutants (min0, min1, min2) allelic to the 5S rRNA genetic locus on chromosome 2 of D. melanogaster were isolated. Flies exhibit a mutant phenotype when hemizygous for a min allele, but flies having two doses are wild-typ... | 103,626 | [
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Endocrine effects of chlorinated hydrocarbons in rhesus monkeys. | After the rhesus monkey was demonstrated to be a suitable model for man in both metabolic and endocrinological studies, effects of hexachlorobenzene (HCB) and polychlorinated biphenyls (PCB) on the pattern of sexual hormones in cycling female rhesus monkeys were investigated. After confirmed ovulation, four adult femal... | 103,705 | [
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Environmental chemical-induced immune dysfunction. | Antibody formation, endotoxin sensitivity, and resistance to a challenge malarial infection were evaluated in mice fed a diet containing polychlorinated biphenyl (PCB) (Aroclor 1242) or hexachlorobenzene (HCB). Antibody synthesis to the antigen sheep RBC (SRBC) was significantly depressed in the PCB- and HCB-treated (1... | 103,706 | [
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Influence of chenodeoxycholic acid on the kinetics of endogenous triglyceride transport in man. | Plasma lipids and triglycerides kinetics were studied in ten subjects before and after 6-8 weeks treatment with 1 g/day chenodeoxycholic acid for radiolucent gallstones. Plasma triglyceride concentration fell by 20% and phospholipid concentration rose by 5% on average; there was no change in cholesterol or free fatty a... | 103,719 | [
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A study of the changes in motor behaviour caused by TRH on intracerebral injection. | 20 microgram TRH injected bilaterally into the caudate-putamen, tuberculum olfactorium, nucleus accumbens, amygdala, lateral ventricles, midbrain or cerebral cortex failed to induce any increase in locomotor activity (measured using photocells), although other behavioural changes were observed after each injection, and... | 103,733 | [
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The retino-geniculo-cortical pathway in Callithrix. I. Intraspecific variations in the lamination pattern of the lateral geniculate nucleus. | Injections of tritiated tracer precursors into one eye revealed a highly variable lamination pattern of the LGN in the marmoset Callithrix. In one specimen, only four cell layers were apparent with some indication of further differentiation. In a second specimen, six almost complete relay layers were found in the occip... | 103,740 | [
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Compartmentalization of prostaglandins and prostacyclin within the kidney: implications for renal function. | When renal function is compromised, the circulation to the kidney is sustained by a major prostaglandin component, withdrawal of which results in significant hemodynamic effects, particularly reduction in blood flow to the inner cortex and medulla. Prostaglandins modulate the effects of vasoactive hormones by attenuati... | 103,756 | [
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Atypical esophageal diverticula associated with progressive systemic sclerosis. | Five cases of unusual esophageal diverticula associated with progressive systemic sclerosis (scleroderma) or collagen vascular disease are presented. These wide-mouthed saccular diverticula were infrequently seen in a group of PSS patients with the typical motility disturbance of esophageal involvement and are reminisc... | 103,770 | [
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Contact sensitivity responses in mice infected with Trypanosoma cruzi. | Mechanisms of depression of contact sensitivity responses in C57BL/10 mice infected with Trypanosoma cruzi were studied. Cellular involvement during sensitization with oxazolone was investigated in mice acutely infected with T. cruzi. Contact sensitivity was not expressed in mice during the latter stages of the acute i... | 103,835 | [
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-0.0809555,
0.1435343,
0.2370103,
-0.6416255,
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-0.4729891,
0.005891993,
-0.3482784,
0.5027798,
0.063095,
0.1747306,
0.1439418... |
A histochemical study about the influence of lytic enzymes on plasma membrane enzyme activities in rat liver and kidney. | 1. The effect of lipolytic, glycolytic and proteolytic enzymes on the activities of plasma membrane enzyme activities in rat liver and kidney has been investigated by a pretreatment of tissue sections with the lytic enzymes. 2. The action of the proteolytic enzymes causes a very strong decrease of leucyl-beta-naphthyla... | 103,867 | [
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... |
Isolation of 57Co-cobalamin coenzymes at high specific activity from Streptomyces griseus. | The distribution of radio-labelled cobalamins in Streptomyces griseus grown in medium containing 57Co-cobalt chloride has been estimated by two-dimensional thin-layer chromatography and bioautography. 57Co-Methylocobalamin (Me[57Co]Cbl) was the major form in the mycelium together with smaller amounts of 57Co-adenosylco... | 103,886 | [
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0.147765,
0.2809878,
0.6396349,
0.4130032,
0.07097963,
0.250640... |
Immunodiagnosis of histoplasmosis in a compromised host. | Three serological tests for the diagnosis of histoplasmosis were compared for sensitivity and specificity in serum from blood bank donors, patients with histoplasmosis, and infected or noninfected immunosuppressed patients. The histoplasmin latex agglutination test was positive in 9% of the normal patients, 33% of the ... | 103,889 | [
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0.06510416,
... |
Counterimmunoelectrophoretic detection of a high incidence of precipitin reactions in normal human sera against staphylococcal teichoic acids and protein A. | The use of counterimmunoelectrophoresis (CIE) for detection of serum antibodies to staphylococcal teichoic acids was evaluated against teichoic acids prepared by sonic treatment or lysostaphin extraction of Staphylococcus aureus (Lafferty strain). Of 54 patient sera from suspected cases of staphylococcal endocarditis, ... | 103,890 | [
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0.2150332,
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0.40... |
Ultrasonography in renal lymphoma. | Ultrasonographic findings in malignant lymphoma of the kidneys in four patients are described. In three patients the kidneys were diffusely infiltrated by anechoic masses showing good acoustic transmission. One solitary lymphoma had the ultrasonographic characteristics of any other kidney tumor. Ultrasonographic differ... | 103,896 | [
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Neonatal detection and evaluation of infantile polycystic disease by gray scale echography. | Infantile polycystic disease (IPCD) is an uncommon pathologic entity involving the kidneys and liver. Gray scale echography can detect this pathologic process within the kidneys, despite the presence of renal failure. In addition, the sonic study may detect associated hepatic abnormalities even though isotopic liver sc... | 103,904 | [
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... |
The complete echographic evaluation of solid renal masses. | In the presence of a solid intrarenal mass, ultrasound scans should not be limited to the mass itself. Modern commercial gray scale equipment is capable of demonstrating both tumor extension into the inferior vena cava and the metastatic disease to the liver. The presence of multiple solid intrarenal masses favors the ... | 103,919 | [
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... |
A preliminary scanning electron microscope examination of wear striation direction on primate teeth. | Wear striations experimentally produced on initially unworn teeth were examined at high magnification using a scanning electron microscope. Certain characteristics of individual wear striations on these teeth indicate the direction of motion that produced them. Other striations on worn teeth of American Indians and the... | 103,950 | [
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Quantitative decision techniques for the health/public sector policy-maker: an analysis and classification of resources. | Policy problems in the health and public sectors are quickly assuming a new level of complexity. Thus, the health/public sector analyst is being confronted with the task of identifying, formulating, evaluating, and making choices among larger and more complicated sets of decision alternatives. Given the context of such... | 103,955 | [
-0.09369151,
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0.3432436,
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0.0... |
A sex-transformation gene in Drosophila melanogaster. | A sex-transformation gene, tra-2OTF, of Drosophila melanogaster is described. The gene is an allele of tra-2 (transformer-2, 7--70+/-), acts only on XX individuals and transforms them into morphologically nearly normal but sterile males. Neither a male-specific lethal gene mle nor the male-killing maternally transmitte... | 103,957 | [
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0.4525072,
0.3762878,
-0.2466173,
... |
Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: II. Genetic analysis of virus recovered during infection. | Five temperature-sensitive (ts) mutants of respiratory syncytial (RS) virus (ts-1, ts-1 NG-1, ts-1 NG-16, ts-2, and ts-7), previously evaluated forinfectivity and virulence in chimpanzees and owl monkeys, were also assayed for in vivo genetic stability. None of the five mutants tested was completely stable genetically.... | 104,003 | [
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0.09399723,
0.3523026,
0.04065701,
0.4086516,
-0.080... |
Center and surround mechanisms of opponent-color X and Y ganglion cells of retina of macaques. | 1. Opponent-color ganglion cells of macaques can be classed as X or Y. Cells with a cone-specific receptive-field organization (center and surround receiving input from spectrally different cone types) have a linear summation, whereas cells with a cone-mixed organization (center and surround partly mediated by input fr... | 104,013 | [
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0.1711854,
0.004943301,... |
Evidence for a transcellular component to the transepithelial sodium efflux in toad skin. | The transepithelial efflux of sodium, from the inner to the outer surface was measured across the isolated toad skin, mostly after abolition of the electrochemical gradient. The effects on this efflux of several agents and manipulations were studied in order to make a distinction between the paracellular component and ... | 104,040 | [
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0.2632442,
0.1661083,
-0.016... |
Vasopressin-like effects of psychotropic drugs in amphibian epithelia. | Amphibian epithelia have been used as models for studying the effects of psychotropic drugs on membrane transport. Several of these agents added to the internal or to the external media, at concentrations greater than 10(-3) M, had inhibitory, "ouabain-like" effects on Na transport. In contrast, stimulatory, "vasopress... | 104,041 | [
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0... |
Neurofibromatous ureteral obstruction relieved by sigmoid conduit cystoplasty. | Neurofibromatosis is a neural disease of hereditary nature affecting both sexes of all races. Visceral and central nervous system involvement can cause serious interference with normal function of affected structures. Under these circumstances, lifelong observation and individualized treatment of the patient are essent... | 104,056 | [
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Long term fixation for histological studies. | It was found that a glutaraldehyde-formalin-phosphate buffered fixative could preserve retinal tissue for light microscopy, even if the tissue remained in the fixative for a month. Retinal tissue that previously was difficult and expensive to procure could now be obtained. | 104,129 | [
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[Inclusion of clinical-dermatological therapy into general practice? (author's transl)]. | The ever increasing expenditures in health service urgently call for a critical revision of the therapy habitually practiced so far. This also includes the complete utilization of ambulatory therapeutic approaches. Moreover, after many years of clinical practice, the dermatologist in general practice should not forego ... | 104,162 | [
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Pituitary and ovarian function in women with congenitally absent uterus. | Pituitary-ovarian function was studied in 2 women with congenital absence of the uterus and the vagina. Daily serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, estradiol-17beta, and progesterone were measured by radioimmunoassay for 1 month. Gonadotropins and ovarian steroids show... | 104,214 | [
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... |
Blurred vision: problems of auditing elective surgery, as seen in an audit of lens extraction for cataract. | Failure to limit the topic can complicate the audit process by producing too many variations and data not relevant to all patients in the study. Because assessment of the need for lens extraction is subjective, formulating justification criteria is difficult; objective evidence that the patient actually needed the surg... | 104,233 | [
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Hematologic toxicity of drugs used in cardiovascular disease. | Many diuretic, antiarrhythmic, and antihypertensive drugs have potential hematologic toxicity. Any patient with cardiovascular disease receiving long-term drug therapy or massive doses of a drug should be watched carefully for early detection of hemolysis, thrombocytopenia, neutropenia, or other toxic effects. | 104,288 | [
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Isolation and characterization of ColE1-derived plasmid copy-number mutant. | The plasmid pBGP120 is a ColE1 derivative that contains elements of the Escherichia coli lac operon and the Tn3 transposon. We have selected and isolated a copy-number mutant of pBGP120. In exponentially growing cultures, the copy-number mutant, pOP1, represents approximately 30% of total intracellular DNA compared to ... | 104,293 | [
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Anticonvulsant action of cannabis in the rat: role of brain monoamines. | The role of brain monoamines in the anticonvulsant action of Cannabis indica resin (CI), against maximal electroshock-induced seizures in albino rats, was investigated by using pharmacologic agents that influence brain monoamine activity. Delta-9-tetrahydrocannabinol content of cannabis resin was estimated to be 17%. T... | 104,333 | [
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Toward the development of a potent, nonsedating, oral analgesic. | The separate and combined analgesic effects of 10 mg of oral amphetamine sulfate and 25 mg of oral anileridine dihydrochloride were studied in 24 healthy, adult, male volunteers. Tolerance of progressively increasing pain produced by the Submaximum Effort Tourniquet Technique was tested four times in each subject: afte... | 104,342 | [
-0.3037852,
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-... |
The effect of gamma-butyrolactone on locomotor activity in the rat. | The effect of gamma-butyrolactone (GBL) on locomotor activity in the rat was studied. Low doses of GBL (100 and 200 mg/kg) had a biphasic effect on activity. Initially, the activity of the rats was reduced, and this reduction was then followed by a period of hyperactivity. The effect of alpha-flupenthixol (50 microgram... | 104,348 | [
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0.08834231,... |
Assessment of renal function following irradiation of the intact spleen for Hodgkin disease. | Twenty-three patients with clinical Stage IA-IIIB Hodgkin disease underwent extended-field radiotherapy, including the intact spleen. In 17 of those patients, there was little evidence of renal dysfunction resulting from partial irradiation of the left kidney, which is inherent in such treatment. While isotopic images ... | 104,362 | [
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0.... |
Enteric fever caused by Salmonella paratyphi C in South and South West Africa. | This article documents 53 cases of Salmonella paratyphi C infections in humans in the Eastern Transvaal (47 cases) and South West Africa (6 cases). Ninety-two percent of patients (49 cases) had enteric fever, 1 patient was asymptomatic, and 3 had localized urinary infections or were carriers. Most patients were success... | 104,399 | [
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... |
Nutritional support of the burned patient. | Patients with major thermal injury exhibit hypermetabolism as a result of neurohormonal alterations. Thus caloric requirements are exaggerated. Failure to provide supranormal caloric intake by both enteral and parenteral routes is associated with pronounced weight loss, delayed wound healing, decreased host resistance,... | 104,400 | [
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... |
The course of infection of trypanosoma cruzi in gamma-irradiated rats. | The course of infection of both blood and tissues by the Sonya strain of Trypanosoma cruzi in gamma-irradiated rats has been investigated. The blood infection was dimorphic; slender and broad forms were present throughout, though broad forms predominated at high parasitaemias. Both total blood parasitaemia and numbers ... | 104,411 | [
-0.04300918,
-0.3309623,
-0.3215072,
-0.2595691,
0.09766717,
-0.3579551,
-0.3537339,
-0.09757697,
0.1162499,
-0.06617023,
0.2242777,
0.06020458,
0.03011095,
0.1398253,
-0.3611135,
-0.03471676,
-0.09923819,
-0.4853905,
0.1036683,
-0.1830863,
0.3183951,
0.2887384,
-0.133914... |
Studies of erythrocyte sequestration. II. Liver homing. | Xenogeneic and enzyme-treated erythrocytes rapidly home to the rat liver as measured by scintigraphic procedures. Histology and scanning electron microscopy revealed that pronase digested erythrocytes are taken up as whole cells by liver histiocytes. | 104,429 | [
0.2036262,
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0.4195325,
-0.014751... |
Failure of the TRH test to predict the clinical course of patients in remission after antithyroid drug therapy for Graves' disease. | In an attempt to assess the predictive value of the TRH test in patients in remission after stopping antithyroid drugs for thyrotoxicosis, 11 euthyroid patients with a subnormal (group I) and 23 euthyroid patients with a normal serum TSH response to TRH (group II) were followed-up for one year. The mean +/- SE interval... | 104,514 | [
-0.01899785,
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0.1828841,
0.1001168,
0.01934778,
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... |
DNA content of cells in human buccal smears. A preliminary study. | The DNA content of the cells from human buccal smears, stained by the Feulgen method, was estimated by absorbtion microdensitometry using a Quantimet 720 D image analyser. It was concluded from measurements that most of the cells in buccal smears contained 2C DNA; however, among the cells from male donors a substantial... | 104,530 | [
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0.0460715,
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0.2619894,
0.5740734,
0.3637816,
0.03408004,
-0... |
The effect of cimetidine, a new histamine H2-receptor antagonist, on renal function. | Serum creatinine, endogenous creatinine clearance, (51Cr)EDTA plasma clearance and the concentration of beta2-microglobulin in serum and urine were determined in 19 patients before and during treatment with cimetidine for peptic ulcer disease. The mean concentrations of creatinine and beta2-microglobulin in serum incre... | 104,553 | [
-0.2168352,
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0.2925302,
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0.06178194,
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0.1298406,
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... |
Intermittent bleeding from minute to minute in acute massive gastrointestinal hemorrhage: arteriographic demonstration. | Acute massive gastrointestinal hemorrhage can be intermittent from minute to minute. This phenomenon is documented by arteriography in three patients. Failure to demonstrate active bleeding by angiography therefore may not prove cessation of bleeding or indicate an inadequate examination. | 104,564 | [
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0.5112732,
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0.1642946,
0... |
Mammographic parenchymal patterns as risk indicators for incident cancer in a screening program: an extended analysis. | In a screening program of self-referred women, different mammographic parenchymal patterns were related to significantly different rates for developing breast cancer. The risk of cancer detection subsequent to a negative mammographic examination was 7.6 times greater for women in the highest parenchymal risk class comp... | 104,567 | [
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0.163934,
0.3837635,
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0.4055082,
0.2586801,
-0.06546365,
... |
The fate of transplanted pancreatic islets in the rat. | Syngeneic pancreatic islets transplanted into the liver or the spleen reverse streptozotocin-induced diabetes in the rat, but allogeneic islets function only briefly and are rejected. Shortly after transplantation, thrombi often form around transplanted tissue, particularly around nonislet tissue that contaminates isle... | 104,625 | [
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0.2682152,
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0.449103,
0.2137601,
... |
An analysis of cercopithecoid odontometrics. II. Relations between dental dimorphism, body size dimorphism and diet. | Odontometric, dietary, and body weight data were collected for a sample of 29 cercopithecoid species. Each species was assigned to one of three diet classes (frugivore, folivore, and omnivore) , and indices were constructed to estimate the extent of sexual dimorphism in body weight, postcanine area and incisor width i... | 104,629 | [
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0.2391306,
0.3304939,
0.04039886,
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0.01132401,... |
Assessment of adrenocortical function in asthmatic patients on long-term triamcinolone acetonide treatment. | The adrenocortical function of 48 adult asthmatic patients on long-term corticoid therapy was studied. All were treated with triamcinolone acetonide (TA) for from two to six (average 3.5 years). The adrenocortical function was assessed using a short Synacthen test as a screening procedure and a five-hour Synacthen test... | 104,641 | [
-0.04652442,
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0.08127218,
0.3090076,
0.1578868,
0.1736365,... |
Cell-mediated and humoral immune responses of cattle to Brucella abortus, Mycobacterium bovis, and tetanus toxoid: evaluation of immunization and assay techniques. | A concentration of 2.5 X 10(-5) M 2-mercaptoethanol (2-ME) added to the medium in lymphocyte blastogenesis assays increased both the uptake of [3H]thymidine in unstimulated lymphocyte cultures and the probability of detecting antigen-sensitized cattle. The use of 2-ME did not cause lymphocytes from unsensitized cattle ... | 104,645 | [
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0.2814656,
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0.04630675,
... |
[The fate of patients with stenosis of the trunk of the left coronary artery]. | We have studied the fate of 49 patients with stenosis of the trunk of the left coronary artery of more than 50%. The follow-up period extends from 1,5 years to 5 years (with a mean of 33.83 +/- 13.55 months). The clinical picture was not characteristic. Unstable angina was found in 59% of cases. The exercice test (29 p... | 104,683 | [
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0.5273966,
0.2957046,
-0.02165391,... |
[Evaluation of cardiac performance in the hypertensive patient. Effect of a beta-blocking agent: atenolol]. | Cardiac output (isotopic dilution method) and systolic time intervals were studied in 11 sustained and 8 borderline essential hypertensive patients, before and after intravenous administration of atenolol, a potent beta-blocking agent. Atenolol decreased significantly (p less than 0.01) cardiac output and heart rate. I... | 104,684 | [
-0.2088381,
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0.3238119,
0.08116426,
0.1702468,
0.1492527,
... |
Purification and effects of fulvocin C, a bacteriocin from Myxococcus fulvus Mx f16. | Fulvocin C is a bacteriocin from Myxococcus fulvus Mx f16. It has a molecular weight of 4672 and is one of the smallest bacteriocins known. Four disulfide bonds give the molecule a tight structure, so that its native form was not attacked by chymotrypsin or pronase. Fulvocin C was stable in various organic solvents and... | 104,692 | [
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0.2060496,
0.07168867,
0.4071812,
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... |
Neurofibromatosis in childhood. | A study of 78 children with neurofibromatosis showed that 40% had an autosomal dominant form of inheritence and a wide variety of manifestations which developed at varying stages during childhood. The pattern of these manifestations differed in many respects from the pattern seen in adults with neurofibromatosis. As a ... | 104,700 | [
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0.3027945,
0.2567753,
-0.1100106,
... |
Prematurity and perinatal mortality in the Rhesus (Macaca mulatta): relationship to birth weight and gestational age. | While the relative influence of birth weight and gestational age in determining perinatal mortality has not been definitively established, it has been assumed that birth weight makes the predominant contribution to perinatal mortality. The joint effects of birth weight and gestational age were examined by analyzing app... | 104,745 | [
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... |
Isolation of Chlamydia trachomatis from Bartholin's ducts. | Exudate from Bartholin's ducts from 30 selected patients was investigated for Chlamydia trachomatis and Neisseria gonorrhoeae. N. gonorrhoeae was isolated from the duct exudate in 24 patients and C. trachomatis in nine. Concurrent infection of the ducts was present in seven (29.2%); the remaining two patients were sexu... | 104,771 | [
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0.1762147,
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0.3484663... |
Effects of Ca, Mg, and EDTA on creatine kinase activity in cerebrospinal fluid. | For one to obtain a precise estimate of creatine kinase (CK) activity in cerebrospinal fluid, the sample fraction is increased by about 10-fold over that used for serum. This increases the concentration of interfering substances, Ca being especially important. Therefore, the relationship between Ca, Mg, and EDTA was ex... | 104,806 | [
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... |
Evaluation of two commercially available laser nephelometers and their recommended methods for measurement of serum immunoglobulin G. | The Hyland and Behring laser nephelometer systems for assay of specific proteins are described. Immunoglobulin G was measured to assess the overall performance of the two systems. Intra-batch precision figures were comparable to those for the radial immunodiffusion method run routinely in our laboratory. There was no s... | 104,807 | [
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Lateralized preferences and right-left discrimination in the monkey: choice of mirror-image shape, position of recovered food and hand usage. | Rhesus monkeys were tested for lateral preferences during mirror-image shape discrimination and food recovery from a row of pellets. Position of recovered food was unrelated to hand preference or mirror-image preference. There was no significant difference in the number of individuals preferring right and left lateral ... | 104,822 | [
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-0.2553496,
0.2184989,
0.1792432... |
The inverse relationship between cost and survival in the critically ill cancer patient. | The enormous cost of intensive multiple organ system support is apparent from patient or third party charges of $1500--$2000 per day exclusive of physician fees sampled during a retrospective review of 700 consecutive recent admissions to the Critical Care Facility of Memorial Cancer Center. Mortality rates of 49% for ... | 104,824 | [
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0.1475246,
0.1297137,
0.1142202,
-0.1424901,
0.52... |
Induced varicoceles in rhesus monkeys. | Varicoceles were surgically induced unilaterally in seveh rhesus monkeys. Effects of the varicoceles were documented by quantitative and qualitative changes in the semen analysis and testicular biopsies. Testicular temperatures appeared to be higher bilaterally in animals with varicoceles. Testosterone and estradiol le... | 104,889 | [
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-0.4988264,
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0.008499618,
0.1359356,
0.4356827,
0.3473513,
-0.166353... |
Effect of auranofin, a new antiarthritic agent, on immune complex-induced release of lysosomal enzymes from human leukocytes. | Auranofin, an oral chrysotherapeutic agent effective in the treatment of rheumatoid arthritis (RA), was found to be a potent, noncytotoxic inhibitor of IgG-RF immune complex-induced lysosomal enzyme release (LER) from human leukocytes. At a concentration of 1 microg Au/ml (5 microM), auranofin produced a marked reducti... | 104,928 | [
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0.2824454,
0.04114676,
0.1259622,
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0... |
The effect of dopamine on renal cortical blood flow in baboons with experimentally induced obstructive jaundice. | The effect of dopamine hydrochloride on renal blood flow in bile duct ligated baboons was assessed using the 133Xe washout technique. Intrarenal infusions of dopamine in different concentrations did not significantly increase renal cortical blood flow. On the contrary, over the lower dose range, the normal dopamine-in... | 104,935 | [
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0.09891619,
0.06235539,
0... |
Rifampin-resistant mutants of Myxococcus xanthus defective in development. | Rifampin, an antibiotic which is known to bind to and inhibit RNA polymerase, was used to probe the molecular regulation of development in Myxococcus xanthus. Rifampin-resistant mutants were screened for defects in fruiting-body formation. About 20% of the isolates in the initial screenings showed major defects in deve... | 104,962 | [
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0.6066234,
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Homology of the gene coding for outer membrane lipoprotein within various Gram-negative bacteria. | The mRNA for a major outer membrane lipoprotein from Escherichia coli was found to hybridize specifically with one of the EcoRI and one of the HindIII restriction endonuclease-generated fragments of total DNA from nine bacteria in the family Enterobacteriaceae: E. coli, Shigella dysenteriae, Salmonella typhimurium, Cit... | 104,972 | [
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0.3049563,
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-0.05... |
Effect of ethylenediaminetetraacetate on phospholipids and outer membrane function in Escherichia coli. | Treatment of Escherichia coli K-12 strain S15, containing a normal amount of phospholipase A, with ethylenediaminetetraacetate (EDTA) resulted in an increase in sensitivity of the organism to actinomycin D. Strain S17, a mutant deficient in both detergent-resistant phospholipase A and detergent-sensitive phospholipase ... | 104,974 | [
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0.2631877,
0.5192692,
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0... |
Purification and partial characterization of three forms of alpha-glucosidase from the fruit fly Drosophila melanogaster. | Three forms of alpha-glucosidase, I, II, and III, have been purified from the whole body extract of adult flies of Drosophila melanogaster in yields of 2.1, 5.3, and 6.7%, respectively. The purification procedures involved ammonium sulfate fractionation, Con A-Sepharose 4B affinity chromatography, DEAE-Sepharose CL-6B ... | 104,985 | [
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0.2851967,
0.595959,
-0.04837117,
0.1822158,
0.2650407,
-0.2278423,
0... |
Studies on human kininogens. I. Isolation, characterization, and cleavage by plasma kallikrein of high molecular weight (HMW)-kininogen. | 1. Human high molecular weight (HMW)-kininogen was highly purified from human plasma by chromatographies on QAE-Sephadex A-50 and CM-Sephadex C-50. Human HMW-kininogen thus purified was a mixture of a single chain and a disulfide-linked pair of chains. Human HMW-kininogen is an acidic glycoprotein having a molecular we... | 104,988 | [
-0.08808603,
0.06579217,
-0.1601648,
0.001867672,
0.1355967,
0.04234104,
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0.04987245,
0.2434911,
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0.1160232,
0.1243371,
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0.0970293,
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0.1149518,
0.09726818,
0.01411161,
... |
Effects of alpha- and beta-D-glucose on germination of spores of Bacillus megaterium QM B1551. | The effects of D-glucose anomers on the germination of dormant spores of Bacillus megaterium QM B1551 were studied, alpha-D-Glucose (1 mM) slightly initiated the germination of the dormant spores during 10 min incubation at 37 degrees C, while about 60% of the dormant spores became germinated with beta-D-glucose (1 mM)... | 104,990 | [
-0.09128597,
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0.05349036,
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0.1220405,
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0.1370044,
0.06541803,
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0.8076871,
0.382374,
0.05490721,... |
The polysaccharides from heterocyst and spore envelopes of a blue-green alga. Structure of the basic repeating unit. | The polysaccharides from the envelopes of heterocysts and spores of Anabaena cylindrica consist of repeating units containing 1 mannosyl and 3 glucosyl residues, all linked by beta(1 yields 3) glycosidic bonds, with glycosidic bonds, with glucose, xylose, galactose, and mannose present in side branches. Degradation of ... | 104,995 | [
0.001088889,
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0.0639189,
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0.07133297,
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0.5913373,
0.4365202,
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... |
Enzyme replacement therapy by fibroblast transplantation: long-term biochemical study in three cases of Hunter's syndrome. | We have assessed the effectiveness of transplanted histocompatible fibroblasts as a long-lived source of lysosomal enzymes for replacement therapy in three patients with Hunter's syndrome, over periods ranging from 2.5 to 3.75 yr. The level of Hunter corrective factor excreted by all three patients increased after tran... | 105,013 | [
0.03147085,
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0.4188329,
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0.09426529,
0.2066899,
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0.2865806,
0.03865327,
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0.1545517,
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0.07058176,
0.3841441,
0.2421242,
0.4034476,
-0.3329537... |
Aspirin inhibits development of coronary atherosclerosis in cynomolgus monkeys (Macaca fascicularis) fed an atherogenic diet. | The effect of aspirin in the primary prevention of diet-induced atherogenesis in cynomolgus monkeys was studied. The diet consisted of 2% cholesterol and 10% butter by weight for 24 wk. Six monkeys received only the atherogenic diet and five monkeys received the diet plus aspirin, 81 mg/monkey per day. Aspirin did not ... | 105,014 | [
0.03556605,
0.3949149,
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0.1728485,
0.2131389,
0.006853818,
0.1900354,
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0.2144095,
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0.01954193,
0.1867827,
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0.2249001,
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0.4407498,
0.2735526,
0.1054256,
0.03163728,
-0.... |
The specificity of the anti-haemagglutinin antibody response induced in man by inactivated influenza vaccines and by natural infection. | The anti-haemagglutinin antibody response in adult human volunteers to inactivated whole virus or tween ether split influenza A/Victoria/75 (H3N2) and A/Scotland/74 (H3N2) virus vaccines was investigated using antibody absorption and single-radial-haemolysis (SRH) techniques. The concentrations of haemagglutinin (HA), ... | 105,040 | [
-0.2119755,
0.0007135544,
0.03335688,
-0.1126317,
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0.03184265,
0.3474568,
0.1087818,
0.3786346,
0.2049699,
0.0881553,
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0.09384136,
-0.1846034,
-0.01909137,
0.3179446,
0.1762142,
-0.4558973... |
Nutritional deficiencies in recurrent aphthae. | A series of 330 patients with recurrent aphthae was screened for deficiencies of iron, folate and vitamin B12. In 47 patients (14.2%) such deficiencies were found; 23 were deficient in iron, seven in folic acid, six in vitamin B12 and in addition 11 patients had combined deficiencies. Clinical examination of the aphtha... | 105,102 | [
-0.2634147,
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0.3406517,
0.01961068,
0.210484,
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0.04587153,
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0.2790298,
0.08256869,
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0.2338741,
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0.1097476,
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0.1532601,
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0.001560876,
0.3024316,
0.2585625,
-0.2506572,
... |
Vascular changes in the pterygopalatine fossa after craniofacial dysjunction surgery. | A study was undertaken to determine vascular changes and the timing of these changes after craniofacial dysjunction surgery. Ten adult male Macaca cynomulgus monkeys were studied with techniques using angiograms and vascular vinyl cast preparations before and after unilateral Le Fort III osteotomy. After surgical disru... | 105,108 | [
-0.1984058,
0.3757563,
-0.2853159,
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0.2902315,
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0.128649,
0.1519445,
0.236137,
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-0.4968831,
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-0.07993726,
0.008645072,
-0.02175453,
0.05471071,
0.06263919,
0.04626764,
0.007919357,... |
The fine structure of elongate gametocytes of Leucocytozoon ziemanni (Laveran). | In an effort to establish comparative data within the genus Leucocytozoon, elongate gametocytes of L. ziemanni from naturally infected great horned owls (Bubo virginianus) were examined by electron microscopy. Micro- and macrogametocytes proved to be easily distinguishable at the electron microscopic level due to drama... | 105,117 | [
0.1024039,
0.3570145,
0.05394304,
0.4125102,
0.0449985,
-0.0749049,
-0.2903356,
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0.2153046,
0.09967035,
-0.07849568,
0.2208681,
-0.2739294,
0.1819879,
-0.4462681,
-0.04268381,
-0.4639785,
-0.2688105,
0.2069248,
-0.1322076,
0.4369228,
0.2464502,
-0.1047388,
0.... |
Ophthalmological findings in 34 patients with Waardenburg syndrome. | In the Netherlands five families with 34 previously unreported patients with Waardenburg syndrome were traced. Twenty-three patients with the syndrome including dystopia canthorum (Type I) were ophthalmologically examined and three patients with the syndrome without dystopia canthorum (Type II) were also examined. Ten ... | 105,123 | [
-0.0860245,
-0.01875674,
0.1496031,
-0.357236,
0.2012479,
-0.2905827,
-0.07786508,
0.04493286,
0.2462332,
0.3265928,
0.2350086,
0.201836,
-0.1761911,
-0.1613502,
0.001905327,
0.2244342,
-0.3291328,
0.1059106,
-0.1561527,
-0.3706999,
0.242995,
0.09465932,
-0.0311859,
-0.... |
Muscle responses and monosynaptic reflexes in falling monkey. Role of the vestibular system. | The free fall has been used in our laboratory as a way to test vestibular function in baboons in order to quantify vestibular compensation in the hemilabyrinthectomized animal. This study presents only those results that concern the contribution of the vestibular system to muscle responses due to sudden fall. EMG activ... | 105,128 | [
-0.1901261,
-0.05978299,
-0.2329957,
-0.1685804,
-0.2902336,
-0.7047005,
-0.4691087,
-0.1066198,
0.2190179,
0.1094647,
-0.03920097,
0.07656551,
0.06017822,
-0.4399205,
-0.1910347,
-0.3146888,
-0.299676,
-0.1948866,
-0.3090622,
-0.03633752,
0.2756871,
0.1276218,
0.03079097... |
Persistent cloaca in a cynomolgus monkey (Macaca fascicularis). | A persistent cloaca was found to occur in a 15-year-old female cynomolgus monkey. This is the first case reported in a nonhuman primate. The embryological basis of this anomaly is discussed, and pertinent anatomical findings in this animal are reported which demonstrate the embryologic defect. | 105,140 | [
0.0460756,
-0.0650532,
-0.123487,
-0.2367381,
0.1199914,
-0.06616662,
-0.512404,
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0.06793872,
-0.04211298,
0.2184777,
0.232238,
-0.1582291,
0.1563293,
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-0.3935528,
0.06921472,
0.01162797,
-0.03852486,
0.06262853,
0.1645885,
-0.06212518,
... |
A serologic survey of mule deer and elk in Utah. | Sera from mule deer (Odocoileus hemionus) and elk (Cervus canadensis) in central and northern Utah were tested for the prevalence of antibodies to 11 diseases communicable to man or domestic livestock. Antibodies to Francisella tularensis (at 1:20) were found in 47 of 88 (53.4%) elk and 1 of 89 (1.1%) deer. A screening... | 105,153 | [
-0.2257857,
0.09967578,
0.4250372,
0.1301582,
-0.3098362,
-0.1747723,
-0.3712298,
-0.0708496,
-0.03534153,
0.05756327,
0.4799586,
0.1760016,
0.3743972,
0.3064688,
-0.2874164,
-0.2058805,
-0.2609574,
0.1237521,
0.2033155,
-0.26063,
0.2803051,
0.123084,
-0.1942054,
-0.300... |
Tryptophan genes in Rhizobium--their organization and their transfer to other bacterial genera. | R. leguminosarum trp alleles mapped by R68.45-mediated recombination were located in three distinct chromosomal regions. We isolated three derivatives of R68.45 that carried different trp genes of R. meliloti. Each of the plasmids suppressed all of the R. leguminosarum trp alleles in a particular region. The R-primes w... | 105,238 | [
0.1068231,
-0.3801277,
0.1849899,
-0.03583099,
0.2248482,
-0.07650547,
-0.2301228,
-0.1462233,
0.1777146,
-0.2019376,
0.2058918,
0.5152605,
-0.1781598,
0.2023487,
-0.5631137,
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-0.1541509,
0.05927742,
0.2645746,
-0.06397051,
-0.04239482,
0.5007284,
-0.3169787,
... |
Murein-lipoprotein of Escherichia coli: a protein involved in the stabilization of bacterial cell envelope. | Two independent mutants of Escherichia coli lacking murein-lipoprotein have been found. One mutant whose mutation was named lpo was subjected to detailed analyses. The absence of both bound and unbound lipoproteins was shown by electrophoretic analysis of 14C-arginine labelled membrane proteins of the mutant. Nor was s... | 105,245 | [
0.1679038,
-0.244207,
-0.03616222,
0.04204352,
-0.02011698,
-0.1600684,
0.0297315,
0.2414625,
0.2455004,
0.2039608,
0.3217702,
0.2860012,
-0.08640964,
0.1004647,
-0.5702675,
0.5354114,
-0.2663999,
-0.05694605,
-0.2231627,
0.123958,
0.466247,
0.09826076,
0.01220842,
0.12... |
rDNA magnification in D. melanogaster: state of rDNA copies following the first step. | D. melanogaster males of XYbb/O genetic constitution undergoing rDNA magnification were mated singly to XXbb+/O females, yielding XYbb/O male progeny, and to XNO- w sn bb+ females, yielding XYbb/XNO- females. The male and female offspring were scored for the bb+ phenotype. Results show that there is a higher percentage... | 105,247 | [
0.1130529,
0.1218281,
0.02149749,
0.1501284,
-0.0865734,
-0.3105031,
0.04416233,
-0.3503606,
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-0.2254372,
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0.2992302,
0.0782057,
0.008722633,
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-0.05014992,
0.1761416,
-0.5020696,
0.417169,
-0.03294799,
-0.0729012... |
[Iron substitution in postoperative anemia during thromboembolic prophylaxis (author's transl)]. | After major operations in 246 patients it was shown that there was no greater blood loss with thromboembolic prophylaxis with heparin and acetylsalicylic acid and healing proceeded undisturbed in view of the demonstrated reductions of hemoglobin and hematocrit which correspond to those of the gynecological operations w... | 105,270 | [
-0.06991903,
0.06100643,
-0.2251161,
0.0259563,
-0.0325324,
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0.1699875,
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0.009330113,
0.05475191,
0.2347107,
0.3761624,
-0.02145038,
-0.2746931,
-0.4014791,
-0.1315786,
-0.1447958,
-0.1472735,
0.0596523,
0.2583693,
0.3126137,
-0.02371438,
-0.3199329,... |
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