title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Acoustic shadowing due to refractive and reflective effects. | Acoustic shadowing may be seen distal to the margins of rounded structures having different acoustic velocities from the surrounding tissue. Refractive and reflective mechanisms for such shadowing are reviewed and in vitro demonstrations of such shadowing are presented. Clinical examples of refractive and reflective sh... | 108,979 | [
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Nutritional survey of hospitalized pediatric patients. | A nutrition survey in a pediatric referral center revealed one-third of patients had evidence of acute malnutrition. Weight for height was below 90% of standard in 46 of 129 (36%), arm muscle area was below the 15th percentile in 67 of 180 (37%), triceps skinfold was below the 15th percentile in 34 of 181 (19%), and to... | 108,993 | [
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Inhibition of short-circuit current by triaminopyrimidine in isolated toad urinary bladder. | The organic cation 2,4,6-triaminopyrimidine (TAP) produced inhibition of short-circuit current (SCC) when added to either the mucosal or serosal surface of the isolated urinary bladder of the toad. Fifty percent inhibition was produced by 10(-3) M TAP in the mucosal solution at pH 6.8 when the mucosal [Na+] was 113 mM.... | 109,013 | [
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Glycogen synthase activation in human skeletal muscle: effects of diet and exercise. | We investigated the role of glycogen synthase in supranormal resynthesis (supercompensation) of skeletal muscle glycogen after exhaustive exercise. Six healthy men exercised 60 min by cycling with one leg at 75% VO2max, recovered 3 days on a low-carbohydrate diet, exercised again, and recovered 4 days on high-carbohydr... | 109,015 | [
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Filtering hospital air decreases Aspergillus spore counts. | We performed counts of airborne spores in a hospital with filtered air where a decrease in nosocomial infection with Aspergillus organisms had been documented. For comparison, similar studies were performed at a nearby general hospital in a ward with open windows. The total spore count inside the hospital with filtered... | 109,022 | [
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Neisseria meningitidis and Neisseria gonorrhoeae bacteremia associated with C6, C7, or C8 deficiency. | We summarize data from 24 previously described or newly diagnosed cases of homozygous deficiency of the sixth, seventh, or eighth components of complement. Thirteen of 24 patients had at least one episode, and usually two or more episodes of Neisseria meningitidis or Neisseria gonorrhoeae bacteremia, or both. Deficienc... | 109,025 | [
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[Possibility of the spectral analysis of heterogeneous biological systems. The determination of the mycelium concentration of Actinomyces aureofaciens, a producer of tetracycline, cultured on a medium with corn meal]. | A possibility of using spectroscopy of attenuated total reflection in the IR region for analysis of the heterogenic system consisting of the microorganisms and plant cells is discussed. The method of spectroscopy is proposed for estimating the mycelium concentration of Act. aureofaciens producing tetracycline in the pr... | 109,035 | [
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[Luteal insufficiency and benign breast diseases. Study in the light of data from the combined LH-RH + TRH test together with the study of ovarian steroids]. | Luteal deficiency has been attributed a patho-physiologic role in benign fibro-cystic breast disease, whereas Prolactin would not be involved in this disease. To tes these hypotheses, patients with fibro-cystic breast disease have been investigated through the combined LH-RH + TRH test, coupled with ovarian steroids es... | 109,032 | [
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Whole body elemental composition during drug treatment of rheumatoid arthritis: a preliminary study. | Thirty-two female patients with rheumatoid arthritis were divided into 3 groups and treated for 6 months with prednisolone, depot tetracosactrin, or indomethacin. Their whole body content of calcium, phosphorus, and nitrogen was measured before and after 3 and 6 months' treatment by in-vivo neutron activation analysis.... | 109,054 | [
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Electromyographical findings in human chronic Chagas' disease. | An electromyographical investigation of 80 patients with chronic Chagas' disease was made. It was found that 79% of the studied patients had EMG manifestations of old and chronic denervation of the upper and lower limbs without clinical features of nervous system involvement. | 109,065 | [
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The course of axons through the retina and optic nerve head. | By identifying degenerating axons in tissue specimens from 22 primate eyes, it was possible to demonstrate the normal course of axon fibers. Nerve fiber bundles from a group of retinal ganglion cells travel together with little tendency to disperse laterally. In addition, axons are stratified such that processes from m... | 109,071 | [
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Nucleoside phosphorylase 2 (Np-2) of mice. | Isozyme patterns of nucleoside phosphorylase (NP) in 16 inbred strains, two recombinant inbred, one congenic, and three species of wild mice were studied. Evidence is provided for a genetic locus, Np-2, encoding an electrophoretic variant which is expressed exclusively in erythrocytes of certain inbred strains. This fi... | 109,081 | [
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Stimulation of defective Gunn-rat liver uridine diphosphate glucuronyltransferase activity in vitro by alkyl ketones. | Addition of alkyl ketone (10mM) to Gunn-rat liver homogenates increased UDP-glucuronyltransferase activity towards 2-aminophenol by 10--20 fold, up to enhanced values of enzyme activity observed with similarly treated Wistar-rat liver homogenates. Alkyl ketones also activate the defective enzyme purified from Gunn-rat ... | 109,085 | [
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[5'-methylthioadenosine phosphorylase from the human prostate. 1. Purification and partial characterization]. | 5'-Methylthioadenosine phosphorylase has been purified approximately 340-fold in 20% yield from human prostate: the use of affinity chromatography by Sepharose-Hg has been found particularly advantageous. The enzyme has been partially characterized and an apparent Km of 2.5 x 10(-5) M has been calculated for 5'-methylt... | 109,102 | [
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Modification of the immunogenicity and antigenicity of rat hepatoma cells. I. Cell-surface stabilization with glutaraldehyde. | gamma-Irradiated rat hepatoma cells are immunogenic in syngeneic WAB/Not rats, so that immunized animals are protected against tumour-cell challenge and circulating tumour-specific antibody is produced. Treatment of the immunizing cells with glutaraldehyde at concentrations of 0.001% or greater for 30 min rendered thes... | 109,110 | [
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Studies on a membrane-bound and solubilized ribonucleotide reductase preparation from Escherichia coli TAU-. | Ribonucleotide reductase has been shown to be associated with the DNA-membrane complex in Escherichia coli TAU- cells. The membrane-bound enzyme has been released in a soluble form using a combined treatment of 1% sarcosyl (pH 8.0) and 1% sodium deoxycholate (pH 6.5). Allotropic differences in the modulatory effects of... | 109,122 | [
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Purification and properties of valyl-tRNA synthetase from Mycobacterium smegmatis. | Valyl-tRNA synthetase from Mycobacterium smegmatis has been purified over 1200-fold by conventional techniques as well as affinity chromatography on valyl-aminohexyl Sepharose columns. The purified preparation is homogeneous by electrophoretic and immunologic criteria. The enzyme is a tetramer of approximate molecular ... | 109,126 | [
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Sister chromatid exchange induction resulting from systemic, topical, and systemic-topical presentations of carcinogens. | Chinese hamster cheek pouch mucosal cells were examined for in vivo sister chromatid exchange formation resulting from the exposure of animals to carcinogens presented in three manners: systemic, topical, and systemic-topical combination. The systemic presentation of cyclophosphamide (5 or 10 mg/kg) through i.p. inject... | 109,193 | [
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Variable oral absorption of hexamethylmelamine in man. | Plasma levels of hexamethylmelamine were measured by a sensitive and specific gas chromatographic assay in 11 patients after they received oral doses ranging from 120 to 300 mg/m2. Peak levels were reached in 0.5--3 hours and ranged from 0.2 to 20.8 micrograms/ml. The area under the curve ranged from 70.2 to 3606.6 mic... | 109,196 | [
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Electron-beam therapy for mycosis fungoides: the Stanford University experience. | The use of high-dose electron-beam therapy for mycosis fungoides at Stanford University is reviewed. Since 1966, 140 patients have been treated in this fashion. Their clinical characteristics including initial extent of disease are reviewed. The results of routine staging studies are examined. Eighty-four percent of th... | 109,207 | [
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Neither dorsal root nor baroreceptor afferents are necessary for eliciting the renal responses to acute intravascular volume expansion in the primate Macaca fascicularis. | We determined the contribution of the dorsal roots, vagi, and sino-aortic nerves to the renal responses to acute isotonic, isooncotic intravascular volume expansion in the nonhuman primate, Macaca fascicularis. Expansion of the estimated blood volume by 15% produced a significant natriuresis and diuresis. There was no ... | 109,231 | [
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Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleoside phosphorylase deficiency. | Urinary orotidine and orotic acid have been determined in a patient with purine nucleoside phosphorylase (PNP) deficiency under various dietary therapeutic conditions. For this purpose a new procedure for the analysis of both compounds has been developed, consisting of prefractionation with Dowex 1X8, followed by two H... | 109,238 | [
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Isolation and renal localisation of urokinase. | Physico-chemical characteristics of urokinase in urine were studied by immunological and chemical methods. By agar zone electrophoresis, commercial urokinase preparations could be separated into an anodic and cathodic fraction. The latter reacted with urokinase antibodies with two precipitation bands. Band I displayed ... | 109,250 | [
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A diurnal melatonin rhythm in primate cerebrospinal fluid. | Melatonin was measured in cerebrospinal fluid (CSF) withdrawn continuously from partially restrained rhesys monkeys. There was a daily rhythm in CSF melatonin with peak night values 2- to greater than 15-fold higher than day values. The increase occurred shortly after lights were turned off, and the decrease occurred s... | 109,277 | [
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alpha-Amanitin: inactivation by bovine lactoperoxidase. | The principle amatoxin, alpha-amanitin, is found to be extremely sensitive toward lactoperoxidase catalyzed degradation, rather than iodination, of the indole nucleus. Extensive attenuation of inhibitor potency against eukaryotic DNA-dependent RNA polymerase II accompanies the treatment of alpha-amanitin with lactopero... | 109,306 | [
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The incidence of complications during pregnancy after treatment of hyperprolactinemia with bromocriptine in patients with radiologically evident pituitary tumors. | The course of pregnancy achieved after bromocriptine therapy is described in nine patients with radiologically evident prolactin-secreting pituitary tumors. In six patients no complications occurred. No changes in sellar size or secondary endocrine deficiencies developed. In three patients, however, complications devel... | 109,323 | [
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Representation of heavy but not light chain Ig idiotypes on T cell receptors for alloantigens. | We have analyzed idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants by the use of different anti-idiotypic antibodies. Such antisera were produced in (Lewis X DA) F1 rats against Lewis anti-DA alloantibodies (= B cell product) and Lewis T lymphocyte receptors with the same sp... | 109,326 | [
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Home parenteral nutrition in children with Crohn's disease: an effective management alternative. | Seventeen pediatric patients, ages 9.25--20.5 yr, were placed on a program of home parenteral nutrition (HPN) for severe, symptomatic Crohn's disease. Prior therapy with sulfasalazine in 14, adrenocorticosteroids in 12, inpatient total parenteral nutrition in 7, and/or surgical resections in 6 failed to suppress diseas... | 109,347 | [
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0.012... |
Immunodiffusion studies of various structural preparations from mycobacterial cells. | Various structures and other preparations from mycobacterial cells were analyzed by immunodiffusion. The preparations were obtained from four strains referred to the species Mycobacterium bovis (BCG), Mycobacterium fortuitum, Mycobacterium phlei and Mycobacterium smegmatis. They represented cell walls (CW), culture fil... | 109,402 | [
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0.2970932,
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Hyperopia and loss of accommodation following ciliary muscle disinsertion in the cynomolgus monkey: physiologic and scanning electron microscopic studies. | Twenty-three cynomolgus monkeys underwent 360-degree disinsertion and retrodisplacement of the ciliary muscle in one eye. Ten to 12 weeks after unilateral disinsertion, resting refraction in the "disinserted" eyes was more hyperopic than in the opposite eyes by 1.12 +/- 0.21 (mean +/- S.E.M.) diopters (p less than 0.00... | 109,411 | [
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0.3091539,
0.1564104,
-0.29... |
Primary intestinal lymphoma in South Africa. | All adult cases of primary intestinal lymphoma seen during the years 1953--77 at Groote Schuur Hospital, South Africa, were reviewed. Seventy percent of patients with solitary lymphoma and 80% with immunoproliferative small intestinal disease were mulatto. Patients in the latter group presented with malabsorption and t... | 109,420 | [
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0.370... |
Membrane-bound D-gluconate dehydrogenase from Pseudomonas aeruginosa. Purification and structure of cytochrome-binding form. | A membrane-bound D-gluconate dehydrogenase [EC 1.1.99.3] was solubilized from membranes of Pseudomonas aeruginosa and purified to a homogeneous state with the aid of detergents. The solubilized enzyme was a monomer in the presence of at least 0.1% Triton X-100, having a molecular weight of 138,000 on polyacrylamide gel... | 109,426 | [
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Formation of intermolecular disulfide bonds on nascent immunoglobulin polypeptides. | The initial step of intermolecular covalent assembly of immunoglobulins molecules involves formation of heavy chain-light chain or heavy chain-heavy chain disulfide bonds. Using QAE-Sephadex chromatography to isolate microsomal nascent polypeptides, we have shown that this initial step of intermolecular covalent assemb... | 109,440 | [
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Studies on the association of cytochrome P-450 and NADPH-cytochrome c reductase during catalysis in a reconstituted hydroxylating system. | The interaction between cytochrome P-450 and NADPH-cytochrome c reductase during catalysis has been investigated with a reconstituted monooxygenase system composed of the two purified enzyme components and synthetic phospholipid. Steady state kinetic data are consistent with a scheme in which the formation of a binary ... | 109,441 | [
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Complement-dependent histaminase release from human granulocytes. | The role of particle-bound complement proteins in the induction of noncytotoxic enzyme release from human granulocytes was investigated with the use of sera genetically deficient in complement and highly purified complement components. Release of histaminase, one of two important histamine catabolizing enzymes, and bet... | 109,469 | [
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0.3515108,
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The immunohistolocalization of carbonic anhydrase in rodent tissues. | Carbonic anhydrase has been localized with an immunoenzyme bridge technique in the following sites in paraffin sections of fixed rodent tissues: gastric parietal cells, the brush border of enterocytes in the small intestine, superficial nongoblet cells of the colon, selective segments of the nephron, glial cells, eryth... | 109,495 | [
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0.1892794,
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Attempts to control clothes-borne infection in a burn unit, 3. An open-roofed plastic isolator or plastic aprons to prevent contact transfer of bacteria. | An open-roofed plastic isolator was built in a single patient isolation room in a burn unit. It was designed to prevent contact contamination only, as this had been shown to be the important route of cross-colonization in the unit. To exclude any possible effect on airborne transfer of bacteria, the isolator was first ... | 109,499 | [
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... |
Adaptive differentiation of murine lymphocytes. III. T and B lymphocytes display reciprocal preference for one another to develop optimal interacting partner cell sets. | Responses to the synthetic terpolymer L-glutanmic acid, L-lysine, L-phenylalanine (GLphi) and hapten derivatives thereof are controlled by two complementing H-2 linked Ir genes in the mouse. F1 hybrids derived from two different nonresponder strains (one of which possesses the alpha and the other beta Ir-GLphi gene) ar... | 109,519 | [
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Shared N-terminal sequences in monclonal IgMkappa and IgGkappa proteins from a patient with a complex multiple paraprotein disorder. | The N-terminal sequence analyses were performed on the heavy (H) and light (L) chains of the idiotypically identical IgM kappa and IgG kappa paraproteins isolated from the serum of patient, Cam. The N-terminal 39 residues of the kappa chains of the IgM and IgG were identical and belonged to the human V kappa III subgro... | 109,522 | [
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C1q: isolation from human serum in high yield by affinity chromatography and development of a highly sensitive hemolytic assay. | C1q, a subcomponent of the first component of complement, has been isolated from human serum in fully hemolytically active form by affinity column chromatography and gel filtration with Bio-Gel A-5M. The affinity column was prepared by covalent coupling of purified human IgG to CNBr-activated Sepharose 4B. Final yields... | 109,524 | [
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0.466069,
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Studies on the terminal stages of immune hemolysis. VI. Osmotic blockers of differing Stokes' radii detect complement-induced transmembrane channels of differing size. | We have previously shown that 0.1 M EDTA could be used to distinguish functionally different transmembrane channels produced during complement-(C) mediated hemolysis of E. In this paper we have studied the ability of sugars of varying Stokes' radii to prevent hemoglobin release from E intermediates whose lysis was inhi... | 109,541 | [
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0.252085,
0.04740978,
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... |
Aging of melanocytes. | Choroidal melanocytes of the eyes of postnatal animals are classified as postmitotic terminally differentiated cells. They have specific granules, the melanosomes, which undergo changes qualitatively and quantitatively correlated to the animal's increasing age. Epidermal melanocytes, which normally divide only on deman... | 109,543 | [
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0.1225803,
... |
Measurement of urinary kallikrein acitvity by kinin radioimmunoassay. | We have established a simplified assay system for the measurement of urinary kallikrein activity by utilizing the sensitive and specific radioimmunoassay system of kinins previously reported from our laboratory. Kinins were generated by incubating urine samples (50 microliter) with kininogen (1500 ng) in the presence o... | 109,645 | [
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0.01999259,
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Fatal tuberculosis in young children. | Three young children with advanced cavitary pulmonary tuberculosis died between 1974 and 1978. Two of the patients had tuberculous meningitis as well. All diagnoses were verified at autopsy; however, all tuberculin skin tests were negative. These instances emphasize the difficulty of establishing the diagnosis of tuber... | 109,806 | [
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Initiation of translation with Pseudomonas aeruginosa phage PP7 RNA: nucleotide sequence of the coat cistron ribosome binding site. | Initiation complex formation between PP7 RNA and ribosomes of Pseudomonas aeruginosa and Escherichia coli has been investigated. The PP7 RNA fragments protected by both species of ribosome have been isolated, and their sequences have been determined. Only one binding sites is available on the intact PP7 RNA strand, and... | 109,813 | [
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0.06664515,
0.1360664,... |
Rapid evolution of animal mitochondrial DNA. | Mitochondrial DNA was purified from four species of higher primates (Guinea baboon, rhesus macaque, guenon, and human) and digested with 11 restriction endonucleases. A cleavage map was constructed for the mitochondrial DNA of each species. Comparison of the maps, aligned with respect to the origin and direction of DNA... | 109,836 | [
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... |
Mutation generating a fragment of the major heat shock-inducible polypeptide in Drosophila melanogaster. | Drosophila melanogaster tissues carrying a third chromosome with the deletion Df(3R)Kar(D2) make a 40,000-dalton (Dal) heat shock protein not made by wild type. The unusual polypeptide was inducible in every tissue examined. Tryptic peptide fingerprints showed it to include part of the 70,000-Dal major heat shock prote... | 109,841 | [
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0.0... |
[Protection from exertion-induced bronchial asthma with disodium cromoglycate (DSCG) (cromolyn, lomudal, intal) and with ketotifen (zaditen). Doubly crossed double-blind study ]. | 16 cooperative asthmatic patients with exercise-induced asthma (with more than 15% decrease in FEV1 after strenuous work on a treadmill with 10% upward; pulse rates over 180 per minute during the work-phase) were selected to take part in a double-blind crossover trial. The 8 women and 8 men, with ages ranging from 15 t... | 109,916 | [
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0.462066,
0.03993791,
0.02714635,
-0.2106... |
Adrenalectomy-oophorectomy and combined chemotherapy for carcinoma of the breast with metastases. | Thirty-one patients with carcinoma of the breast with metastases were treated by adrenalectomy-oophorectomy and randomized either for combined chemotherapy, vincristine, fluorouracil, methotrexate and thiotepa, beginning within one week after operation and continuing for three months or no chemotherapy. Statistical ana... | 109,935 | [
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0.3661926,
0.2473735,
0.3917445,
0.2414695,
-0.1211127... |
Systematic survey of monoclonal gammapathies in the sera from blood donors. | Routine screening of monoclonal gammapathies (M.G.) was performed on the serum of 13,914 blood donors by cellulose acetate electrophoresis. Twenty-six cases of M.G. were detected corresponding to a frequency of 0.19 per cent. The incidence of the M.G. progresses with increasing age comparatively to the age distribution... | 109,954 | [
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0.... |
Liver transplantation--1978. | The development of liver transplantation has been made difficult because of the enormous technical difficulties of the procedure and because the postoperative management in early cases was defective in many instances. With surgical and medical improvements, the prospects for success have markedly increased recently. Th... | 109,961 | [
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0.1700145,
0.1421331,
0.1726897,
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Percutaneous catheter drainage of abdominal abscesses guided by ultrasound and computed tomography. | Ultrasonography and computed tomography were used to diagnose, localize, and guide the percutaneous drainage of 24 intraabdominal and retroperitoneal abscesses in 23 surgical and medical inpatients 16 of whom had abscess formation as a postoperative complication. On the basis of anatomic detail from sectional imaging, ... | 110,038 | [
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-0.2472485,
-0.2126966,
-0.115949,
-0.0774... |
Terminal phalangeal tufts: earliest site of renal osteodystrophy findings in hemodialysis patients. | Direct magnificaiton of the hands of 44 patients on maintenance hemodialysis showed that the earliest unequivocal changes of renal osteodystrophy occur in the tufts. Some workers made a similar observation, but no previous objective study confirmed or refuted the sensitivity of the tufts in the diagnosis of renal osteo... | 110,065 | [
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... |
The hypernephroma halo. | Most renal adenocarcinomas (hypernephromas) are characterized histologically by a dense, avascular, fibrous capsule. This capsule is rare or nonexistent in other benign or malignant renal tumors. The capsule was identified as a thin radiolucent stripe surrounding parts of the tumor periphery in 30 renal angiograms perf... | 110,074 | [
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0.3475455,
0.1449293,
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0.5509527,
0.02403135,
-0.1712603... |
An investigation into the distribution of radial immunodiffusion quality control data. | Quality control data from routine radial immunodiffusion assays for IgG, IgA, IgM, C3, C4 and alpha1-antitrypsin were tested by the Kolmogorov--Smirnov procedure for gaussian distribution. All but alpha1-antitrypsin were nongaussian in type. Further analysis of these date by plotting on log-normal probability paper sho... | 110,133 | [
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0.08097238,
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0.3884299,
-0.0773497,
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0.06174004,
-0.2842043,
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0.2925032,
-0.04894001,
-0.16686,
-0.05508049,
0.09474897,
0.2376893,
0.0411522... |
A guideline for anticipated blood usage during elective surgical procedures. | A realistic guideline for transfusion therapy was prepared, with the cooperation of the departments of anesthesiology and surgery, in order to reduce excessive crossmatching. The guideline recommends an ABO-Rh type and an antibody screen, instead of the ""routine'' two-unit crossmatch, for elective surgical procedures ... | 110,135 | [
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0.3429092,
0.1252641,
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... |
Diagnosis of lymphomatous leptomeningitis by cerebrospinal fluid lymphocyte cell surface markers. | We present a patient with metastatic lymphomatous leptomeningitis in whom the diagnosis was made on the basis of cerebrospinal fluid lymphocyte surface markers and later confirmed by cerebrospinal fluid cytology. The diagnosis of metastatic leptomeningitis can be elusive, and the differential includes a wide variety of... | 110,146 | [
-0.1013545,
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0.02830001,
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0.172605,
-0.1638875,
0.07304579,... |
Enteral and parenteral feeding to evaluate malabsorption in intestinal parasitism. | General evidence of malnutrition such as loss in body weight associated with intestinal parasitism has been attributed to decreased food intake, to intestinal malabsorption, and to change in host basal metabolism. To establish the relative importance of these factors in this regard, rats with trichinosis were studied. ... | 110,162 | [
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0.1093064,
0.1734375,
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0.5060658,
-0.06401385,... |
Operative and postoperative choledochofiberoscopy. | Choledochofiberoscopy is effective for both diagnosis and therapy. It is a valuable diagnostic technic because it permits a definite diagnosis and it allows the surgeon to determine the operative method by direct viewing and by biopsy of the biliary tract wall. Choledochofiberoscopy is therapeutically valuable because ... | 110,167 | [
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0.02533541,
0.04338977,
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... |
Prolongation of pancuronium-induced neuromuscular blockade by intravenous infusion of nitroglycerin. | Based upon clinical observation of undue prolongation of pancuronium-induced blockade in the presence of intravenous infusion of nitroglycerin, neuromuscular blockades produced by pancuronium, succinylcholine and d-tubocurarine were studied in 51 cats using the sciatic-gastrocnemius nerve-muscle preparation. Pancuroniu... | 110,176 | [
-0.3179407,
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0.1189163,
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0.2575519,
0.4644094,
... |
Elevated concentrations in serum immunoglobulins due to infection by ovine progressive pneumonia virus. | Sixty-seven serum samples were obtained from 2 sheep flocks. Agar gel immunodiffusion (AGID) was used to separate progressive pneumonia virus (PPV)-infected sheep from noninfected sheep by the presence of precipitating antibodies. Immunoglobulin (Ig), total protein, and albumin concentrations were then measured from al... | 110,182 | [
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0.1995394,
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0.2829129,
-0.02965384,
-0.2140359,
-0.03539272... |
Pulmonary alveolar proteinosis: analysis of airway and alveolar proteins. | Lavage effluents from the lungs of patients with pulmonary alveolar proteinosis were analyzed for soluble constitutents. Antiserums monospecific for normal plasma components, C-reactive protein, and secretory piece were used to investigate the presence of these proteins in lavage effluent, wheras 2-dimensional polyacry... | 110,187 | [
-0.1004808,
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0.2026056,
-0.329311,
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0.02491017,
-0.1487969... |
Possible correlation between induction modes of hepatic enzymes by PCBs and their toxicity in rats. | Acute toxicity of individual PCBs, which were categorized as either phenobarbital (PB)- or 3-methylcholanthrene (MC)-type inducers, was examined in young male Wistar rats, comparing their effects on growth rate, organ weight and liver lipid content, 5 days after a single i.p. injection. PB-type PCBs (2,4,3',4'- and 2,5... | 110,191 | [
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0.1484941,
0.4010908,
0.4645563,
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0.341374,
-0.3186167,
0.0824... |
Cutaneous melanoma in a patient with neurofibromatosis. | Although neurofibromatosis and cutaneous melanoma are both diseases of neuroectodermal origin, reports of their association are rare. The case history of a patient with histologically documented neurofibromatosis and a nodular melanoma unrelated to a cafe-au-lait spot or congenital nevus is reported, and the literature... | 110,269 | [
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0.2674608,
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0.... |
Selective nonoperative management of contained intrathoracic esophageal disruptions. | Eight patients with intrathoracic esophageal disruptions were managed nonoperatively and without pleural drainage. Criteria for nonoperative treatment included the following: disruption contained in the mediastinum or between the mediastinum and visceral lung pleura; drainage of the cavity back into the esophagus; mini... | 110,275 | [
-0.4548275,
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0.1879961,
... |
Photoreactivation of ultraviolet irradiated blue-green alga: Anacystis nidulans and cyanophage AS-1. | Ultraviolet (UV) inactivation and photoreactivation of Anacystis nidulans and cyanophage AS-1 was studied at different wavelengths. UV inactivation of free phage particles and one and two hour host-phage complexes (intracellular phages) were exponential. UV resistance of plaque forming units was attained at the latter ... | 110,290 | [
-0.09021742,
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0.2387579,
0.3628787,
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... |
Messenger ribonucleoprotein complexes containing in vitro-synthesized 26S and 42S Semliki Forest virus RNA. | An extract derived from Semliki Forest virus (SFV) infected cells is described which catalyzes the synthesis of virus-specific RNAs. The newly-synthesized 26S and 42S RNAs are found complexed with protein as messenger ribonucleoproteins (mRNPs). These mRNPs either are non-membrane bound or are associated with large cyt... | 110,291 | [
-0.1750421,
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0.237454,
0.03349252,
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0.0748... |
Hydrophobic membrane protein from chromatophores of Rhodospirillum rubrum. Structural and spectroscopic studies of monolayers and multilayers. | A hydrophobic, lipid- and pigment-free polypeptide from the chromatophore membrane of Rhodospirillum rubrum was spread from chloroform/methanol, pyridine and formic acid solutions at an air-water interface. Surface pressure versus area isotherms of the monolayers formed at the interface were partially dependent upon th... | 110,346 | [
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0.2228324,
0.1755022,
-0.02834907,... |
Kinetic mechanism of the aliphatic amidase from Pseudomonas aeruginosa. | The kinetic constants for hydrolysis and transfer (with hydroxylamine as the alternate acceptor) of the aliphatic amidase (acylamide amidohydrolase, EC 3.5.1.4) from Pseudomonas aeruginosa were determined for a variety of acetyl and propionyl derivatives. The results obtained were consistent with a ping-pong or substit... | 110,350 | [
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0.3706911,
0.0393598,
0.1536059,
0.1584355,
0.5038871,
-0.186277... |
Characterization of an inhibitor of the intracellular protease from Bacillus subtilis. | A specific inhibitor of intracellular serylprotease from Bacillus subtilis has been isolated from both growing and sporulating cells. Like other protease inhibitors isolated from eukaryotic cells, the inhibitor from B. subtilis is a thermostable protein. A purification method is described. The molecular weight estimate... | 110,359 | [
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0.3139539,
0.2290699,
0.2597047,
0.01613218,
0.2... |
[Myoglobin content and oxygen tension in the muscle tissues in allergic reactions]. | The influence of sensitization to horse serum, brucelia and BCG, and the allergic reactions induced by these antigens, on the oxygen tension and myoglobin content in the muscle tissues was studied. The lowering of myoglobin concentration associated with higher sensitivity formation was noted only in sensitization to li... | 110,378 | [
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0.07373209,
-0.213975... |
Aminopeptidase I activities in several microorganisms. | Aminopeptidase I activity which was found to be localized in the same subcellular fraction and to be similarly heat stable was partially purified by a common procedure from Escherichia coli B, Escherichia coli K12, Enterobacter aerogenes, Salmonella typhimurium, Serratia marcescens Pseudomonas aeruginosa, and Proteus v... | 110,425 | [
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0.1657772,
0.3601677,
0.1248109,
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... |
Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments. | Two hybrid plasmids, 56H8 and 132E3, which contain D. melanogaster (Dm) DNA segments coding for the 70,000 dalton heat shock protein, have been isolated (Schedl et al., 1978). The analysis of the sequence arrangement presented in the accompanying paper (Moran et al., 1979) shows that both Dm segments contain homologous... | 110,461 | [
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-0.0786769... |
The formation of dihydrodiols from benzo[alpha]pyrene by oxidation with an ascorbic acid/ferrous sulphate/EDTA system. | In the oxidation of benzo[alpha]pyrene in an abscorbic acid-ferrous sulphate-EDTA system, four dihydrodiols were detected. Three, trans-4,5-dihydro-4,5-dihydroxybenzo[alpha]pyrene, trans-7,8-dihydro-7,8-dihydroxybenzo[alpha]pyrene and trans-9,10-dihydro-9,10-dihydroxybenzo[alpha]pyrene were identified by their UV spect... | 110,476 | [
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0.3752574,
0.3492813,
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0.0770... |
[Fourier transform analysis of glycolipid depots in Fabry's disease]. | An application of the Fourier Transform Process to the Fabry inclusion study has been made. The study, which rests upon five tissues and eight persons, brings out a new low frequency stratification. Various degrees of freedom exist for the basic molecule association. The periods are given for the three fundamental dire... | 110,486 | [
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0.2526274,
0.2236377,
0.3093427,
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... |
Biochemical and serological studies on Pasteurella multocida isolated from cattle in the Sudan. | Of 42 strains of Pasteurella meltocida isolated from different outbreaks of hemorrhagic septicaemia and from healthy cattle in various parts of the Suden, 38 belonged to Carters' type B and four to type E. The strain used for vaccine production was type E. With respect to somatic antigen determination, there was some c... | 110,516 | [
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0.3532382,
0.2569346,
0.5329152,
0.009609323,
-0.2555774,... |
[The effect of parenteral nutrition on cellular immune status in patients with gastrointestinal cancer]. | In a pilot study, the distribution of lymphocyte subpopulations in the peripheral blood and skin tests with recall antigens have been examined in 42 patients with gastrointestinal cancer before and during a perioperative parenteral hyperalimentation. Concerning the calories and the concentrations of amino acids and car... | 110,558 | [
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0.3609387,
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0.4005105,
0.07969437,
0.3436682,
0.08874536... |
Choleresis and cholestasis produced by infusion of taurocholic acid or taurodehydrocholic acid combined with BSP in the rhesus monkey. | To study the determinants of BSP Tm in rhesus monkeys, animals with indwelling silastic catheters were infused with sufficient BSP to produce a rising plasma concentration and normal saline or taurocholic acid 3.5 mumol/min, 7.0 mumol/min, or 10.5 mumol/min. BSP Tm was 3.84 +/- 0.11 mg/kg/10 min during normal saline in... | 110,571 | [
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0.0171793,
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0.1439141,
0.403556,
0.1566765,
0.3823483,... |
The influence of attending on seizure activity in epileptic monkeys. | Six studies are presented on the influence of attending upon epileptic activity in the alumina-gel monkey model of focal motor and secondarily generalized tonic--clonic seizures. Seizure frequency and EEG paroxysms are reported during (a) scheduled feeding periods, (b) visual attending, and (c) three different operant ... | 110,584 | [
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0.07845528,
0.08295851,
0.3687793,
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0... |
Renal excretion of proteins and enzymes in workers exposed to cadmium. | The proteinuria rate and the relative clearances of beta 2-microglobulin, orosomucoid, albumin, transferrin and IgG were measured in forty-two workers exposed to cadmium and in seventy-seven control workers. A tubular type proteinuria with an increased excretion of beta 2-microglobulin and often also a glomerular type ... | 110,596 | [
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0.08105469,
0.4070978,
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0.... |
Rural and urban family planning services in the United States. | Family planning programs have become more efficient. It cost $66 per patient in 1976 to provide services in both rural and urban programs--the same cost reported in 1971, despite a 40 percent increase in prices since that time. Rural programs are dominated by health departments, lack health professionals, are more like... | 110,616 | [
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0.03395737,
0.2301969,
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Partial trisomy 6p. | A case of trisomy 6p21 leads to 6pter resulting from a maternal balanced t(2;6)(p25;p21) translocation is reported. The main clinical abnormalities were psychomotor retardation, hypotrophy, blepharophimosis, nystagmus, high nasal bridge, small mouth, sacral dimple, and systolic murmur. Other anomalies might have been d... | 110,670 | [
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0.006821611,
... |
[Plasma protein levels during postoperative parenteral feeding]. | In 58 adult intensive care patients, the concentration changes of some plasma proteins and of the immunoglobulins IgA, IgG and IgM were examined postoperatively under parenteral feeding. In three groups of patients with different operations (trepanation, gastrectomy, vascular surgery), the initial and subsequent values... | 110,676 | [
0.147177,
-0.04165671,
-0.6260257,
-0.6032529,
0.1573447,
-0.4555856,
0.1420113,
-0.07200165,
-0.1462839,
0.3756396,
0.337731,
-0.5081033,
-0.007039682,
-0.2646024,
-0.2805145,
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-0.3485654,
-0.05133711,
-0.1544558,
0.1907189,
-0.09565964,
0.09210721,
0.09663899,... |
[Physiologic-chemical parameters during postoperative infusions]. | Individual parenteral alimentation with infusions of combined carbohydrates and amino-acids produced no clinical side effects, however, the electrolyte, acid-base and phosphate balance had to be observed strictly. | 110,678 | [
-0.08515109,
-0.104149,
-0.3282281,
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0.04248996,
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0.2200046,
0.2671814,
0.1053576,
0.007934337,
... |
Behavior of Escherichia coli K antigens K88ab, K88ac, and K88ad in immunoelectrophoresis, double diffusion, and hemagglutination. | Porcine enteropathogenic Escherichia coli strains were found to possess a variant of the K88 antigen provisionally termed K88ad. We propose to include this antigen into the international E. coli typing scheme. Ultrasonic extracts of field strains of E. coli possessing the K88ab, K88ac, or K88ad antigen and their E. col... | 110,679 | [
-0.1960449,
0.1362139,
0.1330036,
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0.1286475,
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-0.7528001,
-0.2044404,
-0.4464098,
-0.08937398,
0.2282192,
-0.05229799,
-0.133421... |
Studies on gonococcus infection. XVIII. 125I-labeled peptide mapping of the major protein of the gonococcal cell wall outer membrane. | The major outer membrane proteins from 10 gonococcal strains were examined after 125I-labeling of the proteins as single bands resolved by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. These 125I-proteins were then treated with either trypsin or alpha-chymotrypsin, and the resultant 125I-peptides were v... | 110,681 | [
-0.04335594,
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-0.09108333,
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0.1352028,
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0.1578767,
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-0.002092539,
-0.2192304,
-0.1474048,
0.4858815,
0.06252706,
-0.32133... |
Effect of type-specific active immunization on the development and progression of experimental Pseudomonas aeruginosa endocarditis. | Rabbits with intracardiac catheters were immunized with heat-killed Pseudomonas aeruginosa or saline and challenged with either 10(9) (high inoculum) or 10(7) (low inoculum) pseudomonas. Immunization did not decrease the incidence of endocarditis when compared with controls, but it did significantly prolong survival. T... | 110,689 | [
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-0.1373989,
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0.004559964,
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0.06844418,
0.1639501,
0.2586327,
0.3396221,
0.09500136,
0.08422442,
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0.113833,
0.06645246,
0.302758,
0.112981,
0.2579523,
0.09442584,
-0... |
Isoproterenol and aminophylline reduce lung capillary filtration during high permeability. | Pseudomonas bacteremia in sheep causes a prolonged increase in lung vascular permeability to protein. Isoproterenol and aminophylline could effect lung fluid balance after Pseudomonas by reducing vascular pressures or by blocking release of permeability mediators. We measured vascular pressures, lung lymph flow, and ly... | 110,756 | [
-0.005060106,
-0.3401901,
-0.3805712,
-0.1398944,
0.06662249,
-0.2105496,
-0.0002085115,
-0.03897882,
-0.06964142,
0.0603463,
0.1031731,
-0.2051408,
-0.1603414,
0.01161069,
-0.0993228,
-0.1040052,
-0.3510666,
-0.1619973,
-0.1362576,
0.09053968,
0.1355164,
0.05560371,
0.15... |
Isolation and structure elucidation of a novel griseorhodin. | Three antibiotics possessing cytotoxic properties were isolated from a strain of Streptomyces griseus (FCRC-57). One was found to be identical with griseorhodin A. A second, FCRC-57-U, was found to be identical to griseorhodin C. FCRC-57-G is a new antibiotic structurally related to griseorhodins A and C, and is active... | 110,759 | [
0.05870393,
-0.1512806,
-0.00387766,
-0.1015297,
0.2374999,
0.2785439,
-0.1224807,
0.09446333,
0.09268192,
-0.05210667,
-0.00147499,
-0.1131854,
-0.03100445,
0.02972255,
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-0.04422574,
-0.5436738,
0.1446672,
0.2574383,
0.06912994,
0.09741615,
-0.01915916,
-0.0780... |
Selective association of the chromosome with membrane in a stable L-form of Bacillus subtilis. | A stalbe L-form (Sal-1) of Bacillus subtilis was found to have retained a markedly modified chromosome-membrane association when compared to intact cells. The membrane-deoxyribonucleic acid complex of the L-form was similar to that of its parental strain in quantity and stability. Genetic analysis of the L-form membran... | 110,772 | [
0.1043534,
0.0009374511,
-0.0864472,
0.00982946,
-0.3265102,
-0.3999101,
-0.3933668,
0.006754737,
0.4230363,
0.08474477,
-0.2104685,
-0.1276224,
-0.008170828,
0.431513,
-0.1242246,
0.1813592,
-0.02467958,
-0.3441695,
0.3612518,
0.08719121,
0.6334316,
-0.0001773338,
-0.406... |
Altered membrane proteins in a minicell-producing mutant of Bacillus subtilis. | The Bacillus subtilis minicell-producing mutant divIV-B1 has a membrane protein profile that is strikingly different from that of the other minicell-producing mutant, divIV-A1, or that of wild-type strain CU403. | 110,785 | [
-0.1056203,
-0.04949791,
-0.001762814,
0.1567814,
0.243536,
-0.3985874,
-0.5290602,
0.06736709,
0.3811811,
0.05001118,
0.1438314,
0.06731319,
-0.02480005,
0.07030606,
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-0.04053562,
0.03933645,
0.1554658,
-0.3833934,
0.3632557,
0.2724371,
-0.2782824... |
Introduction of host-controlled modification and restriction systems of Bacillus subtilis IAM1247 into Bacillus subtilis 168. | Bacillus subtilis IAM1247 had two modification and restriction systems (Bsu1247I and Bsu1247II), the former producing an isoschizomer of PstI endonuclease. A transformant clone was isolated which had Bsu 168, BsuR, and Bsu1247I systems coexisting within a genome. | 110,786 | [
-0.1787951,
0.1640178,
-0.03591423,
0.1249672,
0.1193842,
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0.1476863,
0.4177823,
-0.05765584,
0.0661507,
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-0.2097136,
-0.09419286,
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0.1002011,
-0.406159,
-0.02996279,
-0.04150729,
-0.1845955,
0.1465642,
0.2037352,
-0.1862128,
... |
Genetic location of the Bacillus subtilis sup-3 suppressor mutation. | The sup-3 suppressor mutation of Bacillus subtilis has been located between the aroI and mtlB loci by PBS-1 phage transduction. | 110,793 | [
0.2610056,
-0.309159,
-0.1587075,
0.168799,
-0.2118645,
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-0.3192066,
0.4088826,
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-0.3063199,
0.2882983,
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0.2532063,
0.2842565,
-0.1917561,
0.312273,
0.1102372,
0.7555793,
0.4066906,
-0.08165651,
-0.003487... |
A precursor of cytoplasmic actin in cultured Drosophila cells. | In continuous lines of cultured Drosophila cells two forms of cytoplasmic actin, designated II and III, are detected after a 25- to 120-min pulse label with [35S]methionine. However, only one of these, actin II, accumulates in the cell. With the use of a pulse-chase protocol and two-dimensional gel electrophoresis, it ... | 110,818 | [
-0.1728766,
-0.1897584,
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0.1696945,
0.06603437,
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0.2865247,
0.07268883,
0.0202744,
-0.2045102,
-0.002489507,
0.0349711,
0.2945,
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-0.05833095,
-0.2294359,
0.1368378,
-0.07663918,
0.1378849,
0.641079,
0.3478363,
-0.03846974,
0.1... |
Nuclease enhancement of specific cell agglutination in a serodiagnostic test for Neisseria gonorrhoeae. | Antiserum to a purified type R lipopolysaccharide antigen isolated from Neisseria gonorrhoeae was used in a slide agglutination test and compared with conventional carbohydrate utilization and fluorescent antibody tests to confirm the identity of laboratory cultures classified as typical or "atypical" N. gonorrhoeae. C... | 110,830 | [
0.1089088,
-0.1486389,
-0.05312312,
0.06107807,
0.02277391,
0.2176786,
-0.3286667,
-0.002089899,
0.3119012,
0.11193,
0.204481,
0.2007932,
0.008924043,
0.06638291,
-0.01706813,
-0.08776587,
-0.4735939,
-0.05650236,
0.01164741,
0.05477872,
0.6664493,
-0.1243682,
0.0108796,
... |
Kinetics of biotransformation of clonazepam to its 7-amino metabolite in the monkey. | The pharmacokinetic behavior of the 7-amino metabolite of clonazepam administered exogenously and formed endogenously from the parent drug was studied in a group of rhesus monkeys using constant rate intravenous infusions. Plasma levels of the 7-amino metabolite and/or clonazepam were determined with a GC-CI-MS method.... | 110,917 | [
-0.1321334,
0.008921821,
-0.6285518,
-0.3020986,
0.6217558,
0.2573406,
-0.3486042,
-0.109316,
-0.1090685,
-0.256256,
0.2066438,
0.2355479,
0.1346817,
0.375866,
-0.2460533,
-0.2794107,
-0.6885107,
0.2738332,
0.2663172,
-0.004209437,
0.2151626,
0.1725028,
0.1340975,
-0.26... |
Dietary protein and human pregnancy performance. | Low birth weight is an important predictor of neonatal mortality and morbidity. Women of low socioeconomic classes give birth to disproportionate numbers of low-birth-weight infants and eat poorer diets than those of higher classes. Although maternal weight gain in pregnancy is positively associated with birth weight, ... | 110,926 | [
0.08217918,
0.03014757,
-0.06602875,
0.1874714,
0.08746595,
-0.194688,
-0.2117017,
-0.1527376,
0.1402244,
-0.1668756,
0.112063,
0.1644626,
0.06385421,
0.1432586,
-0.2915513,
-0.4567026,
-0.2779961,
0.3472664,
0.0934798,
0.04073815,
-0.2400099,
0.5576931,
-0.1886898,
0.0... |
Transurethral treatment of urethral diverticula in women. | Six women with urethral diverticulitis and a history of having had previous operations for diverticula were subjected to transurethral diverticulotomy with a knife electrode. Each patient had multiple diverticula, some compartmented, located in the mid or most proximal segments of the urethra. All patients have been re... | 110,944 | [
-0.08105642,
-0.1102024,
-0.1967057,
0.07781636,
-0.3387818,
-0.399586,
-0.3795611,
-0.1382395,
0.05391098,
-0.0206361,
0.2635082,
0.03782716,
-0.02907598,
0.1688078,
0.09864166,
-0.1141067,
-0.01059994,
0.04983235,
-0.1990219,
-0.5421568,
0.2239606,
0.2223198,
0.00943720... |
Subjective distresses of nasogastric tube feeding. | Health care professionals assume that tube feeding is an unpleasant, distressing experience for patients, which is only partially substantiated by experience. Thirty patients were interviewed via a tube feeding and hospital experience checklist (a 47-item interview schedule). Common experiences were operationally defin... | 110,954 | [
-0.2207818,
0.07025263,
0.1027393,
0.07832175,
0.05599799,
-0.04095692,
0.08018439,
-0.3365324,
0.1333707,
-0.1161506,
0.4089434,
-0.5166649,
-0.2337311,
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0.1180173,
0.3329948,
-0.4920679,
0.1616669,
0.1367197,
-0.1428593,
-0.005494936,
0.05823768,
0.154353,
... |
Evolution of the technique of home parenteral nutrition. | Experience with use of the artificial kidney in the home led to the concept of self-infusion of parenteral nutrients at home. Originally called an artificial gut, the term has been changed to home parenteral nutrition. The original method proposed for circulatory access, a side-arm on an A-V shunt, failed and forced th... | 110,955 | [
-0.3376691,
0.08256096,
-0.4309314,
0.1533944,
0.1881241,
-0.258443,
-0.409407,
0.2955004,
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-0.01692448,
0.1103235,
0.03728733,
0.1740022,
-0.2149598,
-0.3579468,
-0.2239682,
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0.1057687,
-0.1719994,
-0.2752859,
-0.07412596,
-0.1045996,
-0.07274711,
... |
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