title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Achalasia of the esophagus associated with Hodgkin disease. | Esophageal achalasia has not been reported in the literature as a complication of Hodgkin disease. Involvement of the esophagus is rare but when present, consists mostly of bleeding, ulceration or diverticuli. A case is reported in a fifty-one year old female with achalasia of the distal third of the esophagus associat... | 110,985 | [
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Lethal effect of protamine and histone on competent Bacillus subtilis cells. Inhibition of genetic transformation by protamine in sublethal concentration. | Under experimental conditions of genetic transformation, protamine and total histone were bactericidal for Bacillus subtilis cells. The abilities to cause lethality were very similar for both, either protamine or histone, with no antagonistic effects amongst these natural polycations. With both basic proteins acting si... | 111,002 | [
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Serotype-dependent inhibition of glucan synthesis and cell adherence of Streptococcus mutans by antibody against glucosyltransferase of serotype e S. mutans. | A crude glucosyltransferase (GTase) preparation was obtained from the culture supernatant of Streptococcus mutans strain MT703 (serotype e) by 50% ammonium sulphate precipitation. Antiserum specific against the GTase was prepared by immunizing rabbits intramuscularly with the GTase in Freund incomplete adjuvant, follow... | 111,004 | [
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[Conformational regulation of functional activity of photosynthetic membranes of purple bacteria]. | In reaction centres of photosynthetic membranes of R, rubrum the efficiency of redox interactions of the photoreduced primary electron acceptor with secondary acceptors and photooxidized bacteriochlorophyll has a marked and reversible dependence on temperature over the range from -20 degrees to -80 degrees. Similar tem... | 111,034 | [
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Patterns of tobacco use in the United States. | Overall, then, the picture of decrease in cigarette smoking is an encouraging one, with the exception of the increased rate of smoking among teenage girls. However, this change probably reflects the tenor of the times and an alteration in the concept of what has traditionally been considered "feminine" behavior. | 111,140 | [
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Alterations in cortical oxygen tension during the development of ischemic cerebral edema in primates (Macaca mulatta). | With a closed head primate stroke model, acute cerebral ischemia limited to the middle cerebral artery (MCA) territory was produced by macrosphere embolization of the internal carotid artery bifurcation. Measurements of the oxygen tension (PO2) at the cerebral cortical surface were obtained by continuous on-line mass s... | 111,152 | [
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[Multiple diverticulosis of the small intestine]. | A case of jejunum-ileum multiple diverticulosis observed during a cholecystectomy due to cholelithiasis, is reported. Stress is laid on this unusual localization of diverticulosis in the small intestine. The clinical picture can be silent or present an acute or chronic symptomatology and radical surgical treatment can ... | 111,163 | [
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[Current status in transplantation of the endocrine pancreas in the treatment of diabetes mellitus 2. Transplantation of fetal pancreas]. | The latest findings support hypotheses that diabetes complications are secondary to metabolic control which current insulin therapy is unable to render constant. Surgical attempts to transplant the pancreas and Langerhans islets in the treatment of diabetes mellitus are reviewed and special attention paid to the use of... | 111,165 | [
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Organochlorine residues in harp seal (Phagophilus groenlandicus) tissues, Gulf of St. Lawrence, 1971, 1973. | Levels of p,p'-DDT, p,p'-TDE, p,p'-DDE, dieldrin, polychlorinated biphenyls (PCBs), and HCB were determined in certain tissues of 31 harp seals (P hagophilus groenlandicus) taken from the Gulf of St. Lawrence during 1971 and 1973. The seals ranged in age from less than two weeks to 18 years. Mean concentrations of PCBs... | 111,215 | [
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Effects of adrenaline administration on the activity of glycogen metabolizing enzymes in different muscle types. | Adrenaline administration which leads to glycogen changes different in fast and slow twitch muscles (Gorski, 1978) causes very similar acute changes in the activities of glycogen synthase I and of glycogen phosphorylase 'a' in these two types of rat muscle. | 111,217 | [
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Apurinic acid endonuclease activity from mouse epidermal cells. | An endonuclease activity making single-strand breaks into depurinated and alkylated DNA has been purified 500-fold from carcinogen-transformed mouse epidermal cells. The enzyme was active only at apurinic/apyrimidinic sites, regardless of whether they were produced by heating at an acidic pH or by alkylation with the u... | 111,231 | [
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Leptospirosis and acute renal failure--clinical experiences and a review of the literature. | About 50 cases of leptospirosis are diagnosed each year in the United Kingdom, with an overall mortality of 5%. Renal failure, in association with jaundice, is commonly held responsible for this figure. Over a period of 18 years, 6 cases of leptospirosis complicated by renal failure were treated at the Royal Air Force ... | 111,233 | [
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Mood alterations during deanol therapy. | An imbalance between central cholinergic and adrenergic influences may affect mood disorders. Of 38 patients taking high doses of deanol, a putative acetylcholine precursor, eight developed changes in mood: five became depressed and three became hypomanic. A predisposition is suggested as seven of these eight patients ... | 111,283 | [
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Interaction of alcohol and reward in an achievement situation. | Effects of psychological stress on acute alcohol intoxication following intake of 2 ml whisky/kg body weight were examined in 12 healthy subjects. Each subject performed a 45-min psychomotor task under four conditions, two of which increased achievement stress by promising the subject a monetary reward for rapid and ac... | 111,286 | [
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Paradoxical effect of amphetamine in an endogenous model of the hyperkinetic syndrome in a hybrid dog: correlation with amphetamine and p-hydroxyamphetamine blood levels. | A telomian-beagle hybrid has been studied as a possible model for the hyperkinetic syndrome in children. Behavior tests showed that hybrids, like children, exhibit hyperactivity, impulsiveness, and impaired learning. Two groups of hybrid could be differentiated; the behaviour of one improved after amphetamine (responde... | 111,287 | [
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Naloxone effects on schedule-controlled behavior in morphine-pelleted rats. | The effects of morphine pellet implantation and naloxone administration were examined in rats lever pressing under inter-response time schedules of food presentation. Subcutaneous implantation of a morphine pellet initially decreased lever-pressing rates. Tolerance to this effect developed within 3--4 days. Naloxone (0... | 111,298 | [
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[Diverticula of the duodenal orifice]. | The authors present a synthesis of data from the literature, as well as of particularities that have confronted them in connection with 16 observations of mucous diverticuli of duodenal windows (of which 7 were interposed and 9 were juxtaposed). After a definition of the window diverticuli, of their types and of their ... | 111,314 | [
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Investigation of a valuable biochemical indicator in radiotherapy. I. Immunological tests and reticulocyte number. | Patients with different cancers were treated by 200-kV X-rays, high-energy X-rays and 60Co-gamma rays. Changes in the immunoglobulin level were observed by immunoelectrophoresis qualitatively and by immunodiffusion quantitatively. Reticulocyte count was made in smears. It was concluded that immunoelectrophoresis was on... | 111,375 | [
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Competitive inhibition of cytotoxic T lymphocyte-target cell conjugation. A direct evaluation of membrane antigens involved in cell-mediated immunity. | A method to determine directly the antigenic similarity of target cells (TCs) involved in cytotoxic T lymphocyte (CTL)-TC interactions is described. When fluorescently labeled TC (FL-TCs) are bound (conjugated) to CTLs in the presence of antigenically similar but unlabeled TCs, the percentage of CTL-TC conjugates conta... | 111,379 | [
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Role of catecholamine degradative enzymes and the adrenergic innervation in determining the cerebrovascular response to infused norepinephrine. | Cerebral blood flow responses to intra-arterial infusion of norepinephrine (NE) at 0.55 microgram/kg/min and 1.1 microgram/kg/min were studied in 3 groups of baboons. The flow was measured by the intracarotid 133xenon clearance technique using a computer program to calculate flow (height over area--H/A) flow (initial s... | 111,378 | [
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[Biochemical and hematological changes in sows during estrus]. | After the second and fourth parturition of piglets, ten clinically healthy sows, weaned on the second day of life, were subjected to examination two to three days before heat, during heat (defined by typical changes on the outer genitals and immobilization in the presence of a boar) and two days after insemination. Dur... | 111,395 | [
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[Dynamics of urea concentration in blood cells of the domestic fowl during early post-incubation ontogenesis]. | Urea was determined by means of diacetyl monoxim in the blood cells of 80 cockerels of the initial breed White Leghorn, commercial hybrid Primant. The highest urea concentration was ascertained on the 15th day of life: 392.33 +/- 85 mg per 10(12) blood cells. The content of urea in the blood cells irregularly deceased ... | 111,396 | [
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[Pathogenicity of aerobically sporulating microorganisms: Bacillus cereus]. | The pathogenicity of the metabolites of B. cereus was determined by bioassays with white mice, chick embryos, rabbits, and kittens. Cell-free filtrates of the cultures of several strains of B. cereus were used for application; in the mice the application was done i. v., i. p. and p. o., in the chick embryos via the all... | 111,402 | [
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Failure of anti-D immunoglobulin to remove fetal red cells from maternal circulation. | A Rhesus negative female was found post delivery to have circulating cells of fetal origin. The neonate was typed as D-positive. In spite of more than conventionally adequate doses of anti-D immunoglobulin given to the mother, the fetal cell count in the maternal circulation remained unchanged. Further investigation sh... | 111,422 | [
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Sibship asymmetries of rhesus blood groups in the presence of maternal antibodies. | The genotypes of the children of R1r, R2r, and R1R2 fathers, and Rh-immunized rr mothers, were examined. R1r fathers had an excess of R1r over rr children, and R1R2 fathers had an excess of R1 r over R2r children. These asymmetries confirm the findings of a previous study. The possibilities of artefactual self-selectio... | 111,423 | [
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Erythroid repopulating ability of bone marrow cells in polycythaemic mice. | The erythroid repopulating ability (ERA) of femoral bone marrow cells was determined in polycythaemic CBA, C57Bl and Balb/c mice. Polycythaemia was induced by hypertransfusion or exposure to chronic hypoxia in silicone rubber membrane enclosures. The results obtained demonstrate decreased ERA after both types of polycy... | 111,453 | [
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The effect of centrally administered TRH on blood pressure, heart rate and ventilation in rat. | Different doses (3, 16, 80, 400 and 2 000 ng per rat) of TRH or alternatively saline were infused into the lateral ventricle of urethane-anaesthetized rats and blood pressure, heart rate, respiration rate and tidal volume were recorded. A dose of 3 ng TRH caused a significant elevation of blood pressure and heart rate,... | 111,471 | [
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Complications of central venous catheterization. | The complications of central venous catheterization are discussed in a review of experience and of the literature. The anatomy surrounding the subclavian and internal jugular veins is described. Indications and contraindications of catheterization are reported. Common and unusual complications are discussed and illustr... | 111,506 | [
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0.001139938,
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0.4526838,
0.1746562,
-0.09373601,
-0.2228589,
-0.2522039,
0.2273211,
-0.48589,
0.06407348,
0.2827124,
0.1662586,
-0.2767996,
0.3915506,
0.1142926,
0.05364123,
0... |
Coagulation abnormalities induced by Russell's viper venom in the rhesus monkey. | Coagulation studies were carried out in a group of non-human primates (rhesus monkeys) following envenomation with lethal and sublethal doses of Russell's viper venom. The envenomated animals showed significant fibrinogenopenia in association with or without disseminated intravascular coagulation. The findings offer a ... | 111,572 | [
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0.3163153,
0.00532377,
... |
Acute complications of jejuno-ileal pseudodiverticulosis: surgical implications and management. | Acute inflammatory complications of jejuno-ileal pseudodiverticulosis that necessitate surgical intervention are attended by excessive mortality rates of 20 to 40 per cent primarily because of delay in diagnosis. Early diagnosis is confused by the frequent coexistence of other gastrointestinal pathology, most commonly ... | 111,574 | [
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0.08520633,
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0.06114833,
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-0.298949... |
Structure of the soft palate and composition of the oral mucous membrane in monkeys. | The soft palate of monkeys (M. irus, mulatta, fasciculata; 2.3 +/- 0.4 kg in weight) was studied morphologically and stereologically. After fixation by perfusion, the tissue was disected free, divided in halves and the halves into 5 segments each, and processed for light, transmission- and scanning electron microscopy.... | 111,581 | [
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0.1431857,
0.321952,
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... |
A fine structural analysis of the myelin sheath in rat spinal roots. | The present study is concerned with the fine structure of the myelin sheath in rat and monkey spinal roots. Pictures are obtained that show that the intraperiod gap of the myelin sheath is continuous and opens into both the internal and external mesaxons, which in turn open into the periaxonal and endoneurial extracell... | 111,582 | [
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0.05185802,
0.1589326... |
Hemoperfusion to treat intoxications. | Hemoperfusion is being increasingly proposed and used for the treatment of a large variety of exogenous intoxications. This procedure has been shown to achieve high clearance rates of most common intoxicants, and case reports have claimed that its application has been, on occasion, life-saving. We tabulated our experie... | 111,596 | [
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0.2546496,
0.0006302609,
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0.1874682,
0.2905415,
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Left main coronary artery stenosis: hemodynamic monitoring to reduce mortality. | A review of 20 consecutive patients with left main coronary artery stenosis operated on in 1976 indicated a general hemodynamic pattern characterized by systolic hypertension and an increase in heart rate that occurred early during the induction phase of anesthesia. From January through August, 1977, 28 patients with t... | 111,640 | [
-0.1412453,
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0.2234147,
0.1960896,
0.007747873,
0.4443968,
0.1728272,
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Short term effects of Clophen A 50 and of dichlorobiphenyl in rats. | In short term experiments, rats were treated with single oral doses of the polychlorinated biphenyls (PCB's), Clophen A 50 (high chlorinated compound) and dichlorobiphenyl (low chlorinated compound). Clophen A 50 treatment resulted in a marked increase in liver weight and in the activities of GPT, GOT and G1DH in rat s... | 111,646 | [
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0.01121854,
0.5695962,
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0.4663217,
-0.0368496... |
[Age and thymus morphology of pavian hamadrils]. | By different histological methods, 23 thymi have been studied in Papio hamadryas of 5 age groups: fetuses, newborn, one-year-old, mature and old animals. By morphometric methods percentage of quantitative relations of the cortical and medullary substances, as well as their cell composition have been estimated. A rather... | 111,648 | [
0.2018323,
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0.1744298,
0.3589874,
0.3802765,
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... |
Peroxidatic oxidation of benzo[a]pyrene and prostaglandin biosynthesis. | The arachidonic acid dependent oxidation of benzo[a]pyrene to a mixture of 3,6-, 1,6-, and 6,12-quinones has been studied by using enzyme preparations from sheep seminal vesicles. Maximal oxidation is observed at 100 microM benzo[a]pyrene and 150 microM arachidonic acid. The arachidonic acid dependent oxidation is pero... | 111,706 | [
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0.1499475,
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0.2550048,
0.5308259,
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0.6319685,
0.3042225,
-0.0800350... |
The phosphoenolpyruvate : methyl-alpha-d-glucoside phosphotransferase system in Bacillus subtilis Marburg : kinetic studies of enzyme ii and evidence for a phosphoryl enzyme ii intermediate. | The Enzyme II complex catalyzing the phosphoryl transfer from P-HPr to sugar in the inducible methyl-alpha-D-glucoside : phosphotransferase system in Bacillus subtilis acts according to a ping-pong mechanism, implying a phosphorylated Enzyme II intermediate. This result is supported by the demonstration of a specific t... | 111,719 | [
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0.09205276,
0.06682388,
0.7245347,
0.03246962,
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The treatment of difficult cutaneous basal and squamous cell carcinomata with electrons. | The use of electron beam therapy with energies up to 10 MeV in the treatment of basal and squamous cell carcinomata of the skin is described. The results of treatment of 15 cases are presented with photographs of six cases. Excellent clinical and cosmetic results have been obtained. Electron therapy has been found to b... | 111,748 | [
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0.0509457,
0.5324103,
0.441484,
0.1163004,
0... |
Regioal distribution of immunoreactive neurotension in monkey brain. | The regional distribution of immunoreactive neurotensin (IRNT) in 66 different areas of the monkey brain and spinal cord was studied by radioimmunoassay using specific rabbit antisera to synthetic neurotensin. Each area was found to contain IRNT in uneven concentrations. Highest concentrations were present in the hypot... | 111,778 | [
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0.08370744,
0.001705281,
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0.1757137,
-0.077295... |
Monkey pyramidal tract neurons and changes of movement parameters in visual tracking. | During a single-step visual tracking task of monkeys, parametric changes of the wrist extension-flexion movement and related discharge rate changes of pyramidal tract neurons (PTNs) of hand-arm motor area were studied. The task consisted of preparatory, precontraction, contraction and target periods. If the displacemen... | 111,780 | [
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0.2685286,
0.02799877,
0.2918172,
0.06203579,
... |
Thymidine and thymine in biologic fluids during high-dose infusions of thymidine in mice, monkeys, and man. | Measurements were made to determine if millimolar thymidine (TdR) concentrations, shown to have antitumor activity in vitro, could be attained in vivo. An adaptation of an ion-exclusion liquid chromatography method was used to quantitate TdR and thymine in various biologic fluids. Millimolar concentrations of TdR were ... | 111,798 | [
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0.1900291,
0.2127579,
0.08163727,
0.103875,
... |
[Immunohistochemistry of the basal plate of the full-term human placenta : x cell characterization with anti-hCS and anti-hCG sera labeled with peroxidase]. | Immunohistochemical reaction with peroxydase has been applied in human full-term placentas for the detection of the cells of the basal plate containing hCG and hCS. This reaction was positive with both optic and electronic microscopes in the so-called X cells. This fact seems to confirm the trophoblastic origin and the... | 111,829 | [
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0.1410403,
0.3522267,
0.2742313,
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0.... |
[In vitro malignant transformation of hamster lung cells by 2-chlorobutadiene]. | Normal Hamster lung cells from an established line were treated with 1-500 microgram . ml-1 2-chlorobutadiene. Those treated with 1 microgram . ml-1 of the compound showed malignant transformations 14 weeks after treatment. The treatment with higher concentrations did not accelerate the transformation process. | 111,835 | [
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[Occurrence of circulating immunocytes in the process of graft rejection in nemertines of the genus Lineus (acelomate invertebrates)]. | Performed upon bispecific Lineus chimaeras of a suitable constitution, the grafting of tissues excised from nemerteans of a third Lineus species resulted in a confrontation between graft cells, fixed cells from one chimaera component and mobile cells which originate from the second chimaera component. Survival of such ... | 111,838 | [
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0.5312653,
0.3151252,
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0.0... |
[Primary and secondary cerebral lesions produced by kainic acid injections in the rat]. | Systematic (i. p.) or intra-amygdaloid injections of kainic acid elicit typical generalised convulsive seizures with typical electrographic correlates. Depending on the survival time and the amount of neurotoxin administered, secondary pathological damage is invariably found in various brain structures removed from the... | 111,839 | [
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0.3183845,
0.1784905,
0.2145317,
0.2063309,
0.00428524,... |
[The corneal stroma and its physical properties]. | The author has studied the correlation existing between the transparency of the corneal stroma and its microscopic fine structure. The paper is an analysis of the results obtained through diffraction and specular approaches. In addition, the paper gives an objective means to determine the ocular spectral characteristic... | 111,847 | [
0.134649,
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... |
[Measurement of the position and intensity of chromosomal denaturation bands by an automatic system]. | The band density profile of a marked chromosome was obtained using a photodiode collector combined with a minicalculator, working with an ordinary photographic document. The measurement was carried out over 10 to 20 300-point lines oriented longitudinally along the chromosome. The profile obtained corresponds to the su... | 111,850 | [
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0.6144373,
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0.... |
[Immunocytologic differentiation of hypophyseal innervation in carp using anti met-enkephalin and anti-alpha-endorphin serums]. | The immunocytological reactions with anti-met-enkephalin and anti-alpha-endorphin reveal two types of fibres in the intermediate lobe of the Carp. Their pathways through the adenohypophysis and the localization of their terminals are different. The anti-met-enkephalin positive fibres terminate mainly in a zone close to... | 111,863 | [
0.126035,
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0.2511742,
0.2671594,
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-... |
Immunological and structural properties of human monoclonal IgG cryoglobulins. | Structural and immunological properties were determined for sixteen IgG and one Bence-Jones, human monoclonal cryoglobulins. The heavy chain subclass percentages were 47% IgG1, 14% IgG2 and 29% IgG3, and were different from previously reported distributions of myeloma proteins. In addition, 69% (eleven out of fifteen) ... | 111,883 | [
-0.3977417,
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0.1943152,
-0.05117068,
-0.1361201,
0... |
The effect of estrogen on the tubal epithelium of immature ovariectomized rhesus monkey (Macaca mulatta). | The effect of 3 doses of estradiol dipropionate (EDP) on tubal epithelium of immature ovariectomized rhesus monkey (Macaca mulatta) was studied under both light and electron microscopy. EDP at a dose of 5 microgram/kg/day for 6 consecutive days changed differentiation of the epithelial cells into clear and dark cell-ty... | 111,917 | [
-0.1805227,
0.1454385,
-0.1328569,
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-0.4181492,
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-0.1741305,
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0.3563145,
0.4656422,
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-0.1627306,
-0.08935153,
0.3514911,
0.2027034,
0.35147... |
Identification and characterization of a 19-S complex containing a 27 000-Mr protein in Artemia salina. | The cytoplasm of the cryptobiotic Artemia salina gastrula contains a large quantity of a unique 19-S complex. This particle is a specific aggregated form of a 27 000-Mr protein, having a molecular weight of 10(6) and an apparent buoyant density of 1.25 -- 1.26 g/cm3 in sucrose and 1.31 g/cm3 in CsCl. The relative quant... | 111,924 | [
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0.1246867,
0.3162121,
0.5267522,
0.3501767,
-0.150267... |
Characterization of long guanosine-free RNA sequences from the Dahlemense and U2 strains of tobacco mosaic virus. | Four naturally occurring strains of tobacco mosaic virus, U2, Dahlemense, CV4, and the bean form of tobacco mosaic virus, were tested for the existence of long T1 RNAase oligonucleotides analogous to the oligonucleotide omega found in the common or U1 strain of tobacco mosaic virus and which makes up the 5' non-coding ... | 111,935 | [
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0.1822959,
0.3348615,
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0.5037219,
0.4053895,
-0.2816438... |
A clinical comparison of 2 h and 4 h bone scans obtained with 99Tc H.E.D.P. | A comparison of 2 h and 4 h bone scan images obtained with technetium labelled H.E.D.P. in ten patients demonstrated no increase in lesion detection rate between the 2 h and 4 h scans. The 2 h bone scans were of sufficient quality to permit identification of tumours in all cases. | 111,937 | [
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... |
Beneficial effects of colchicine in experimental nephrotoxic serum nephritis in the rat. | Glomerulonephritis was induced in rats by multiple injections of rabbit anti-rat kidney serum. Colchicine was administered daily for 4 months to nephrotoxic serum treated rats and untreated control animals. Nephritic rats receiving colchicine had significantly less proteinuria and less glomerular damage than unprotecte... | 111,949 | [
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0.09457352,
0.1595369,
-0.2692233... |
Studies on insulin secreted by isolated islets of the monkey, Macaca radiata radiata. | The effects of various experimental conditions during the isolation of monkey islets by the collagenase method on the insulinogenic response of the isolated islets to glucose have been studied and compared with rat islets isolated under similar conditions. The monkey islets gave a normal response for at least 120 min. ... | 111,984 | [
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Radiologic abnormalities and autonomic neuropathology in the digestive tract of the ketonuric diabetic Chinese hamster. | Barium x-ray patterns of ketonuric diabetic Chinese hamsters displayed marked dilatation of the stomach, small and large intestine. Hypomotility was manifested by flocculation of barium in the small and large bowel. Impaired transit time was further characterized by prolonged emptying of the stomach (mean 570 min diabe... | 111,990 | [
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0.06067838,
0.2130408,
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0.1234906,
0.2015879,
0.262151... |
The development, enhancement, and reversal of the secondary complications of diabetes mellitus. | Diabetic glomerulopathy continues as a major problem in the management of the patient with diabetes mellitus; however, evidence in man and in animals underlines the fact that good control of diabetes favorably alters the course of this complication. Islet transplantation in the diabetic rat returns plasma glucose and i... | 112,028 | [
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Another family with purine neucleoside phosphorylase deficiency. | A brief genetic report is given on a family with a child affected by nucleoside phosphorylase deficiency. Our observations confirm the genetic heterogeneity of this enzyme deficiency which is inherited as a mendelian autosomal trait. | 112,034 | [
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0.2525168,
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Release of soluble peptidoglycan from growing gonococci: hexaminidase and amidase activities. | Peptidoglycan (PG) turnover in exponentially growing Neisseria gonorrhoeae RD5 type 4 was accompanied by release of soluble PG fragments into the medium. Turnover of the D-[14C]glucosamine-labeled glycan moiety and of the meso-[3H]diaminopimelic acid (DAP)-labeled peptide region occurred at similar rates (ca. 35% per g... | 112,060 | [
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... |
Purification and partial characterization of rat liver bilirubin glucuronoside glucuronosyltransferase. | Bilirubin glucuronoside glucuronosyltransferase (EC 2.4.1.95) converts bilirubin monoglucuronide to bilirubin diglucuronide and is concentrated in plasma membrane-enriched fractions of rat liver homogenates. The enzyme was purified 2,000-fold to homogeneity from rat liver. The pI of the enzyme is 7.9 +/- 0.2. The enzym... | 112,100 | [
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0.5587005,
0.252766,
0.06425922,
0.064... |
Lymphocytes with immunoglobulin E Fc receptors in patients with atopic disorders. | Lymphocytes from normal nonallergic donors and patients with atopic disorders were analyzed for subpopulations bearing Fc receptors for immunoglobulin (Ig)E (Fc(epsilon)) and IgG (Fc(gamma)), surface IgM (sIgM) and IgD (sIgD), and for T cells forming spontaneous rosettes with sheep erythrocytes (E). The patients were d... | 112,109 | [
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0.3524594,
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0.1378244,
0.0242788... |
Differential diagnosis of hypoechoic and anechoic masses with gray scale sonography: new observations. | With the technological advances in gray scale sonography that have permitted the use of higher-frequency transducers and expansion of the acoustic dynamic range, increasing problems in differentiating solid masses and fluid-filled masses have become apparent. These difficulties can be overcome by strict adherence to pr... | 112,111 | [
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... |
Nutritional support in patients with malignant disease. | Clinicians have long been aware of the major nutritional and metabolic abnormalities that occur in patients with cancer. Such abnormalities are varied and hence both the indications and techniques for their correction are also diverse. The aim of the present paper is to consider certain specific aspects of nutritional ... | 112,180 | [
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0.2133191,
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Murine cell surface immunoglobulin: two forms of delta-heavy chain. | The heavy chain of isolated murine cell surface IgD is present in two forms, separable by electrophoresis on SDS-polyacrylamide gradient gels. Both forms of delta-heavy chain are present on the surface of intact spleen cells and have apparent m.w. of approximately 70,000 (delta1) and 68,000 (delta2). Treatment of surfa... | 112,186 | [
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... |
Model of the bacterial flagellar motor: response to varying viscous load. | A model of bacterial flagellar drive by cytomembrane streaming is described and applied to experiments of bacterial propulsion under varying viscous load. The theory predicts a linear dependence of the reciprocal propulsion velocity on the viscosity of the suspension medium, if the velocity of cytomembrane streaming fa... | 112,211 | [
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0.02218176,
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Dopamine-dependent hyperactivity in the rat following manipulation of GABA mechanisms in the region of the nucleus accumbens. | The effect of manipulation of GABA mechanisms in the region of the nucleus accumbens on dopamine-dependent locomotor hyperactivity in the rat has been studied. Two models of hyperactivity were used: (1) the injection of dopamine into the region of the nucleus accumbens in nialamide-pretreated animals and (2) the system... | 112,217 | [
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0.07268801,
... |
Pigment in the lining of nasopalatine duct cysts: report of two cases. | In a review of 20 nasopalatine duct cysts, two cases were encountered with a pigmented epithelial lining. In the literature we have found one similar case only. The pigment in our cases was shown to be melanin. The authors suggest that the melanin-containing epithelial cells are derived from Jacobson's organs and, ther... | 112,232 | [
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... |
Responses of retinal rods to single photons. | 1. A suction electrode was used to record the membrane current of single rod outer segments in pieces of toad retina. During dim illumination the membrane current showed pronounced fluctuations. 2. Amplitude histograms of responses to dim flashes of fixed intensity exhibited two discrete peaks, one at 0 pA and one near... | 112,243 | [
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0.03839621... |
[Clinical evaluation of cefazedon on patients with urinary tract infections (author's transl)]. | The efficacy and tolerance of Cefazedon, a new antibiotic, was investigated clinically on 90 patients with urinary tract infections who also required surgical treatment. Good clinical results were achieved in over 90% of patients after 6 to 7 days of treatment. The bacteriological examination revealed complete eliminat... | 112,365 | [
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0... |
[Neurological cardinal symptoms of internal diseases (author's transl)]. | The old rule:"Frequent is frequent, Seldom is seldom" is only true of etiological entities. With symptoms and syndromes which are hastily diagnosed as "typical" or "atypical" just because they are frequent, serious misdiagnoses may occur and critical details both in the history and in the physical examination may be ov... | 112,407 | [
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0.09156879,
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[Bowen carcinoma following many years' use of a "radium cushion" (author's transl)]. | A case is reported of a 73-year old female patient in whom precancerous symptoms appeared in the mid-abdominal area of application which for a long time were mistaken for chronic eczema, until after 7 years the development of a skin carcinoma was clinically and histologically confirmed. The case provides a reason to dr... | 112,420 | [
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0.... |
[Mountain sickness or alpine climber's disease (author's transl)]. | The symptoms of mountain sickness extend from slight malaise to severe clinical disease. From our own observations in the Himalayas the most serious symptoms appear at night, i. e. at less than the meximum height achieved and when physically at rest. The etiology is not completely clear; the reduced oxygen partial pres... | 112,448 | [
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0.06731786,
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[Advances in the conservative treatment of acute traumatic cerebral edema. Controlled clinical trial with follow-up examination (author's transl)]. | Studies in 142 accident victims with severe craniocerebral trauma showed that the intravenous application of sodium escinate over several days considerably reduced the dangerous rise in intracranial pressure and also the total mortality in comparison with corticosteroid therapy alone. Both groups, each of 71 patients, ... | 112,457 | [
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0.4487914,
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0.2136013,
... |
Audiometric and histologic correlates of the interaction between kanamycin and subtraumatic levels of noise in the chinchilla. | Difficulty in assessment of potentiating interaction between noise-induced and kanamycin-induced injury of hearing is compounded by the great variability of intersubject response to the same drug dosage. However, in a given subject, response of the two cochleas to kanamycin intoxication may resonably be assumed to be s... | 112,529 | [
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0.2060032... |
Head and neck manifestations of relapsing polychondritis: review of 29 cases. | This review of 29 patients with relapsing polychondritis seen at the Mayo Clinic between 1962 and 1976 emphasizes the head and neck manifestations of the disease and the role of the otolaryngologist in its diagnosis and treatment. The major clinical features included inflammation of the pinna, eye involvement, nasal ca... | 112,539 | [
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Treatment of sudden hearing loss with diatrizoate meglumine (Hypaque). | Between March and November 1976, 30 patients with sudden hearing loss (SHL) were treated with vasodilators and diatrizoate meglumine (Hypaque). Nine (30%) of the patients had a good response, 7 (23%) had a moderate response, and 14 (47%) had no response to treatment. Most of the patients who responded were treated with... | 112,564 | [
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0.01847534,
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0.07536... |
Measurement of stopping power ratios for 60 MeV positive or negative pions. | Pion stopping power ratios are essential parameters for pion radiotherapy treatment planning. The validity of scaling proton stopping powers to pions is called into question since the pion mass is intermediate between the electron and proton masses. Direct measurements of stopping power ratios with respect to water wer... | 112,597 | [
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... |
Amenorrhoea, body weight and serum hormone concentrations, with particular reference to prolactin and thyroid hormones in anorexia nervosa. | Twenty women with anorexia nervosa were investigated at varying stages during weight gain. Basal prolactin and TSH and prolactin responses to TRH were normal and unrelated to body weight. LH, FSH and 17 beta oestradiol were low in emaciated patients and rose with weight gain. There was no correlation between serum gona... | 112,613 | [
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... |
Effect of morphine on the brain histamine levels in stress-exposed rats. | The effect of morphine on brain histamine levels in stress-exposed rats was investigated. It seemed that the brain histamine level was not directly affected by stressors. However, morphine induced a sharp rise in the brain histamine levels in both morphine-treated and morphine-treated stressed groups. This effect of mo... | 112,615 | [
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0.03126474... |
Acute effects of alcohol on saccadic eye movements. | Four components of 20 degrees horizontal saccadic eye movements, i.e., latency, mean and maximum velocities, and duration were measured in 16 students under the influence of alcohol and also in a control situation. The experimental procedures were standardized and automated as much as possible. Latency (simple eye reac... | 112,616 | [
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0.1219984,
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Effects of chlordiazepoxide on maze performance of rats subjected to undernutrition in early life. | The purpose of this research was to study the isolated effects of and interactions between undernutrition and emotional reactivity upon maze performance in rats. This work compares the effects of chlordiazepoxide on learning performance in two groups of adult rats: one undernourished early in life and then rehabilitate... | 112,618 | [
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... |
Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics. | Oral challenge tests with acetylsalicylic acid, tartrazine or benzoic acid were performed in 7 intolerant asthmatic patients after a 3-day treatment with either orally taken ketotifen (1 mg twice daily) or inhaled disodium cromoglycate (20 mg four times daily) at random. Protection was noted with ketotifen in 5, with D... | 112,656 | [
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0.09727226,
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-0.1093535,
0.04074664,
0.3159027,
-0.004932676,
0.2467252,
-0.08133415,... |
[Epilepsy and pregnancy: preliminary studies]. | The study concerns 17 clinical cases of epilepsy during the progress of 32 pregnancies. It is reported the frequency variations of epileptic fits, the eventual pharmacological adjustments and also some parameters of influence on the newborn. The result are briefly argued. | 112,667 | [
-0.02751621,
0.008917854,
0.01032411,
0.06155783,
0.04093404,
-0.4257023,
-0.3702726,
-0.2740118,
-0.03769607,
0.06190484,
0.1422992,
0.2433254,
0.1492132,
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-0.2884482,
0.2533186,
0.01059821,
0.1908733,
-0.01672388,
0.08925324,
-0.05144... |
Use of a macrophage cytotoxicity system to show macrophage activation by Listeria monocytogenes cell wall fraction. | Experiments were conducted to determine whether a partially purified listeria cell wall fraction could stimulate macrophages to high levels of activation. To detect activation of macrophages, a macrophage-mediated cytotoxicity system were established. The data demonstrate that listeria cell wall components are capable ... | 112,673 | [
0.1268591,
-0.244107,
-0.210947,
0.1321109,
0.2191359,
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0.1432242,
0.06495021,
0.1309692,
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0.2093529,
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0.05302077,
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0.1928894,
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0.1450662,
-0.07975712,
0.3170414,
0.3638982,
0.1484414,
-0.1543901,
0.19... |
Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. | Depletion of dopamine in a circumscribed area of association cortex in rhesus monkeys produces an impairment in spatial delayed alternation performance nearly as severe as that caused by surgical ablation of the same area. This behavioral deficit can be pharmacologically reversed with dopamine agonists such as L-dopa a... | 112,679 | [
0.03615249,
0.1379932,
-0.2097804,
-0.1580655,
-0.02063641,
-0.2952671,
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0.2227474,
0.1583572,
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0.1523769,
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0.2927444,
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0.06324937,
0.08700393,
0.07248832,
-0.04135048,
0.2358058,
0.05525637,
... |
[Results from radiotherapy of cancer of the vallecula or of the base of the tongue obtained in 171 patients between 1950 and 1976 (author's transl)]. | The results of radiotherapy in 171 patients with cancer of the base of the tongue or vallecula from the period between 1950 and 1976 are reported. 19% of all patients were cured (5 years no evidence of disease). There is no difference of the cure rate between conventional kilovoltage and highvoltage irradiation. In ear... | 112,724 | [
-0.01264219,
-0.3329741,
-0.1264868,
-0.2589705,
0.1374604,
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0.02499955,
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0.4138263,
0.01743067,
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0.2875304,
0.3333288,
0.3450477,
0.5420896,
0.5029923,
-0.1905141,
0.3... |
[Clinical diagnosis and course of arteriosclerosis obliterans]. | The great diagnostic importance of the clinical heart and circulation state as well as of the simple clinical functional tests in comparison to the apparative bloody and unbloody diagnostics is emphasized. Concerning the course the unfavourable prognosis is elaborated on the basis of the survival rates and the appearan... | 112,790 | [
-0.01978978,
0.1326468,
-0.006506278,
-0.1217443,
0.06145282,
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0.1647887,
0.3475293,
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-0.3231501,
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0.2945765,
0.2970777,
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-0.09255749,
0.1376204,
0.01853806,
0.2342843,
0.3428538,
0.07903143,
-0.3475342,... |
Thyroid status in fifty patients with alcoholic cirrhosis. | Because the liver is of considerable importance in metabolism of thyroid hormones, plasma levels of thyroxine (T4), triiodotyronine (T3) with their unbound fractions (FT4 and FT3), reverse T3 (rT3)--an inactive isomer of T3-tyrotropin (TSH) and TSH response to thyrotropin releasing hormone (TRH; 250 micrograms i.V.) we... | 112,793 | [
-0.1464158,
-0.1194763,
-0.3540018,
-0.1157319,
0.07781132,
-0.3717804,
0.1856279,
0.2464581,
-0.1335176,
0.3495551,
0.1385642,
0.0276074,
-0.09715039,
0.01071537,
-0.1441409,
-0.2971868,
-0.1534332,
0.224757,
0.06242362,
0.1203354,
-0.1116631,
0.3503966,
-0.01174093,
-... |
[Toxins and enzymes of several species of Bacillus, especially of the B. cereus-thuringiensis group (author's transl)]. | In the examined strains the production of following toxins or enzymes was determined by bioassay or by semiquantitative and routine diagnostical tests: delta-endotoxin, alpha-exotoxin, beta-exotoxin hemolysin, phospholipase C, proteinase. The production of delta-endotoxin (= a parasporal crystal toxic for several insec... | 112,804 | [
0.02112828,
-0.1361843,
-0.1594086,
-0.08265795,
-0.08573472,
-0.2235456,
-0.02445644,
0.2569782,
-0.03195417,
-0.1453409,
-0.03272991,
0.2239405,
0.0125575,
0.01953129,
-0.4940371,
0.1083715,
-0.51737,
0.08732431,
0.3964886,
0.1933234,
0.6094455,
0.2724249,
-0.04988657,
... |
[Effect of successive electric stimulation of different brain regions on delayed spatial choice in monkeys]. | The effect of paired successive electrical stimulation of the prefrontal cortex, hippocampus, caudate nucleus head and mediodorsal nucleus of thalamus on the delayed spatial choice was studied in two rhesus monkeys. During the first second of delay one structure was stimulated, during its last second--another one. It w... | 112,800 | [
-0.00542772,
0.1437915,
-0.07842083,
0.008476606,
0.3333186,
-0.3981228,
-0.3801971,
-0.2701381,
-0.1326134,
0.2500014,
0.04936863,
0.1052359,
-0.2103172,
-0.2770218,
-0.5719482,
-0.1671142,
-0.2041834,
0.08300887,
-0.444103,
0.1533574,
0.2865628,
0.1644897,
0.151258,
-... |
[Ability of birds of the Corvidae family to operate by the empirical dimensions of figures]. | The reasoning ability was investigated in 29 Corvidae birds. The experimental task consisted in finding a hidden bait, the task being based on the fact that volumetric bait could be hidden in a volumetric geometrical figure only and not in a flat one. Thus it was possible to value the bird's ability to operate the empi... | 112,801 | [
-0.07784594,
0.4310293,
0.2123944,
-0.07988027,
0.4047796,
-0.4388261,
-0.2414298,
-0.1314849,
-0.03083972,
-0.01360232,
0.1973116,
0.1025729,
-0.01704243,
-0.06359854,
-0.7126511,
0.07271991,
-0.6519755,
0.3328245,
-0.05269388,
0.323269,
0.3580154,
0.1726714,
-0.06108824... |
[Interaction between the hippocampus and posterior hypothalamus in actualization of the orienting reflex]. | Unit activity of the dorsal hippocampus in response to electrical stimulation of the posterior hypothalamus was recorded in 3--3.5 months old alert rabbits in chronic and acute experiments. Electrical stimulation of the sties of the posterior hypothalamus which had produced orienting behavior in preliminary tests, led ... | 112,802 | [
0.001990381,
-0.2196136,
0.008887289,
0.2117262,
0.1482886,
-0.5702416,
-0.1418851,
0.02799754,
-0.1448397,
0.1965451,
-0.1254076,
-0.00813847,
-0.09205935,
-0.3292978,
-0.2063282,
-0.3027717,
-0.3727412,
0.2514612,
-0.003477508,
-0.07797493,
0.2764333,
0.01624068,
0.0598... |
The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome. | The degree of autonomy in prolactin secreting pituitary adenomas and also prolactin secretory reserve in cases with suspected functional galactorrhea syndrome was evaluated with the use of metoclopramide, TRH and L-DOPA. It was found that in patients with pituitary adenoma the basal prolactin (PRL) level often exceeded... | 112,817 | [
0.1265794,
-0.4433826,
-0.009669477,
-0.4018997,
0.0546592,
-0.254052,
0.04063591,
-0.3825745,
-0.1711225,
0.3525835,
0.2069746,
0.2067762,
-0.3442314,
0.105317,
-0.07609046,
-0.3322924,
-0.4308617,
0.3603349,
-0.09073955,
-0.06781984,
0.3633334,
-0.07430921,
0.02774606,
... |
[Fluorescence histochemical investigations on the topic of GABA and dopamine in the neostriatum of the rat (author's transl)]. | In the neostriatum of adult rats the distribution of Dopamine and GABA was investigated by means of fluorescence histochemical methods. There is a different mode of distribution of the transmitters in this brain region. The animals were treated with cycloserin, acting as an inhibitor of the GABA transaminase, in order ... | 112,831 | [
0.1879735,
-0.1969889,
-0.1627321,
0.1759772,
0.1179051,
-0.4453871,
0.02251239,
-0.330823,
0.03035547,
-0.04807147,
0.08032866,
0.08589208,
0.1736055,
-0.1520633,
-0.5578253,
-0.2409461,
-0.6277772,
0.42872,
0.1549731,
0.632203,
0.2538176,
0.3397879,
0.08692127,
-0.065... |
Comparison of fetomaternal hemorrhage detection methods and Rh immune globulin usage. | A 1977 College of American Pathologists survey of hospitals has been analyzed to compare Rh immune globulin usage (RhIgG) with methods used to screen and confirm fetomaternal hemorrhage (FMH). The survey data show that there is a correlation between the rate of multiple vial usage and the confirmation method used. Labo... | 112,853 | [
-0.2357913,
0.2047389,
-0.5622694,
-0.08857409,
0.3779823,
-0.04405084,
-0.02215633,
-0.01690783,
0.09099635,
0.239168,
0.1895538,
0.4272884,
-0.1434422,
0.1357156,
-0.08055512,
-0.2183956,
0.2211289,
-0.08866153,
0.1069045,
0.1512797,
0.4425948,
0.2515116,
0.192547,
-0... |
Histology of wound, vitreous, and retina in experimental posterior penetrating eye injury in the rhesus monkey. | We performed a histologic study to support our clinical observations on the mechanisms responsible for traction retinal detachment after a penetrating injury in the rhesus monkey eye. The monkey eyes (40 eyes; 40 monkeys) were characterized by intraocular fibrosis with the formation of a cyclitic membrane and epiretina... | 112,870 | [
-0.3147624,
-0.05856714,
-0.07537803,
-0.114581,
0.1359421,
-0.1952391,
-0.1775291,
0.3042002,
0.2198298,
0.3477134,
0.02684174,
-0.3531962,
-0.09432931,
-0.1727248,
0.1234176,
-0.2154369,
-0.4802427,
0.3049472,
-0.2384233,
-0.01349245,
-0.1362309,
0.197937,
-0.1869342,
... |
Interstitial anion distribution in striated muscle determined with [35S]sulfate and [3H]sucrose. | The distributions of a charged and an uncharged extracellular tracer in the interstitial spaces of skeletal and heart muscles were examined in vivo by a double-labeling technique. 35SO4(2-) and [3H]sucrose were simultaneously injected intraperitoneally into rats and toads, and extracellular volume was determined in the... | 112,873 | [
-0.114601,
0.2562453,
-0.3412529,
0.3825179,
-0.08855555,
-0.2283122,
0.06536971,
0.3074484,
-0.2321633,
-0.05709099,
0.1107421,
-0.04291585,
0.101036,
-0.06076983,
-0.3469178,
-0.1928677,
-0.3920618,
-0.05515327,
-0.1750686,
-0.127661,
0.0117438,
0.3095698,
0.03308187,
... |
Specific granules of the rat atrial muscle cell. | The specific granules found in the atrial cardiac muscle cells of the normal rat were studied. The ultrastructural appearance of these granules demonstrated a fixative-dependent lability. Fixation with cacodylate buffered aldehydes yields three types of granules. However, fixation with phosphate buffered aldehydes or p... | 112,880 | [
-0.141272,
-0.0505162,
-0.3147325,
0.0446359,
-0.1464344,
-0.403339,
0.139854,
0.213019,
0.1028908,
0.04524096,
-0.04306598,
0.1067906,
0.1007029,
0.08934509,
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0.04838274,
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-0.2176845,
0.4373301,
0.2658913,
0.2290954,
0.1788884,
-0.09671237,
0.1794... |
Penetrability of the outer membrane of Neisseria gonorrhoeae in relation to acquired resistance to penicillin and other antibiotics. | Acquired antibiotic resistance in Neisseria gonorrhoeae is principally associated with three genetic markers, penA, mtr, and penB. penA is a specific marker for penicillin resistance, whereas mtr and penB are nonspecific in conferring resistance to penicillin and several other antibiotics as well. It has been suggested... | 112,915 | [
-0.08141036,
-0.2373804,
-0.02998183,
0.07310753,
0.3715935,
-0.2531724,
-0.008034727,
0.2103676,
0.2353887,
0.05569432,
0.2414113,
0.3463478,
0.02447557,
0.2873273,
-0.1652877,
-0.1611551,
-0.5629771,
-0.01398443,
-0.4754077,
0.1815927,
0.3567826,
-0.1303039,
0.2832541,
... |
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