title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Drug resistance in newly discovered untreated tuberculosis patients in Poland, 1974-1977. | Between March 1974 and November 1977 altogether 2568 strains from 509 newly discovered, previously untreated tuberculosis patients from many areas of Poland were tested for susceptibility to 4 antituberculosis drugs: isoniazid (INH), streptomycin (SM), ethambutol (EMB) and rifampicin (RMP). Twenty seven patients (5.3 %... | 120,628 | [
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[Decarboxylase activity study of Pasteurella multocida]. | Ornithine-, lysine- and arginine-decarboxylase activity of 218 P. multocida strains, isolated from birds of varying disease symptoms in Bulgaria and CSSR, and from pigs, rabbits and birds in Cuba, USSR and CSSR, was studied after the method of Moller. Positive ornithine decarboxylase activity was established in 211 str... | 120,631 | [
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[Effect of varying amounts of lysine in the ration on chickens]. | The effect of varying lysine quantities given in the daily ration to 20 day-old chickens was studied for a 40 day-period. Highest body gain (157% as compared to the control group) was observed in group I (0.20% lysine). Two and four per cent of lysine in the ration reduced the basic body gain by 69.7% and 66.9% respect... | 120,632 | [
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[Plasma testosterone, free testosterone fraction LH and FSH in males during the early stage of acute myocardial infarction (author's transl)]. | In 18 males (age 49--79 yrs) without endocrine diseases, testosterone, free testosterone fraction, LH, FSH and cortisol (as indicator for stress) were determined in the early stage of an acute myocardia infarction. Blood was taken on admission as well as every 4 hours up to meanly 43 hours. The patients were separated ... | 120,643 | [
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[Examinations about the mutual influence of bacteria in aqueous medium with minimal nutritive substances (author's transl)]. | Experiments were done about the behaviour of 5 different strains of St. aureus (= St), E. coli (= Ec), Se. marcescens (= Se) and P. aeruginosa (= Pa) in aqua bidest. at 30 degress C and 40 degrees C. In the first part the smallest quantities of Standard-I-broth (Merck) were evaluated where the diverse bacteria-species ... | 120,653 | [
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[Coronary lesions due to aortic valve disease. I -- Occurrence and clinical prognosis]. | A multicentre retrospective study of 467 cases of operated aortic valve disease was undertaken to define the indications of coronary arteriography in the pre-operative work-up. Significant coronary artery disease was present in 15% of all cases or, more precisely, in 17% of cases with angina and in 8% when investigatio... | 120,716 | [
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[Health insurance and hypertension. Review of current data]. | Medical insurance gives a very incomplete view of the spectrum of hypertensive disease, based only on the results of clinical examination of persons undergoing check-ups in the Medical Examination Centres: 39 850 in 1976, or on those examined by consulting physicians according to article L293: 23 308 in 1976, or being ... | 120,722 | [
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Isolation of inner cell masses from mouse blastocysts by immunosurgery or exposure to the calcium ionophore A23187. | Two techniques have been evaluated for their use in routinely isolating inner cell masses from mouse blastocysts by destroying the trophectoderm. The most efficient method of immunosurgery was a 15-min incubation in a 1:50 dilution of rabbit anti-mouse spleen antiserum followed by a 30--60-min incubation in guinea pig ... | 120,740 | [
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[Vitamin D and reproduction in Wistar rats]. | Females have received from weaning a semi-synthetic diet (0,35% Ca; 0,32% P; 0,03% Mg), with or without vitamin D (+/- D). Fertility of these females was not changed. At weaning, the young from mothers--D had lower weight, calcemia and phosphatemia, but the ash content of the femur was the same as for young from mothe... | 120,790 | [
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Providing saline reacting anti-D cell typing reagent. | Since 1969, when anti-D specific IgG was made available to protect recently delivered D negative women from sensitisation by fetal D positive cells, the supply of saline acting anti-D, suitable for reagent use has diminished. The same immunized male blood donors that provide the anti-D for the production of the specifi... | 120,796 | [
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Profile changes of bone and soft tissues following vestibular sulcus extension by the operation of Edlan and Mejchar. A 2-year follow-up study-II. | The progression of alveolar resorption and the alteration of the soft tissue profile of the chin were studied in 15 patients operated on by the vestibular sulcus extension technique of EDLAN & MEJCHAR. Lateral cephalograms and tracings exhibited an apparently accelerated bone resorption of the alveolar crest. Furth... | 120,857 | [
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Enzyme-linked immunosorbent assay for immunological diagnosis of human tularemia. | The enzyme-linked immunosorbent assay (ELISA) was applied for immunological diagnosis of human tularemia, using lipopolysaccharide from Francisella tularensis as antigen. Sera collected from patients, healthy individuals, and vaccinated volunteers were investigated for antibodies against F. tularensis by ELISA and tube... | 120,873 | [
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Indirect hemagglutination test for detection of antibody to Rickettsia rickettsii in sera from humans and common laboratory animals. | Antibody production in humans and three species of laboratory animals infected with Rickettsia rickettsii was determined with the indirect hemagglutination test. Rabbits, guinea pigs, and mice were inoculated with R. rickettsii and bled at intervals. Antibody which agglutinated both fresh and glutaraldehyde-fixed sheep... | 120,875 | [
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Synchronization of division in vitamin B12-starved Euglena gracilis. | Vitamin B12 deficiency arrests cell division in Euglena gracilis. B12 starvation for short periods made it possible to induce synchronous growth by addition of the vitamin. Culture conditions were established to optimize replenishment synchrony. The DNA content of E. gracilis in steady state culture and vitamin B12 def... | 120,896 | [
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7-Acetylcytochalasin B: differential effects on sugar transport and cell motility. | Cytochalasin B (CB) is a potent inhibitor of sugar transport and cell motility in animal cells. We have synthesized and characterized the CB derivative 7-acetylcytochalasin B (CBAc) and have found that it has differential effects on transport and motile processes in fibroblasts. The derivative inhibited sugar transport... | 120,908 | [
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Effects of microwaves on organisms. Ptychodiscus brevis--Gomphosphaeria aponina interactions. | The two referenced organisms have been subjected to microwave irradiation (2,450 MHz CW). Initial experiments indicated no statistically significant loss of cell numbers as a result of simple temperature rise (6 degrees C) or experimental manipulation. Cell survival for P. brevis one week after irradiation was related ... | 120,925 | [
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Neuroanastomosis of orthotopically transplanted palmaris longus muscles. | Palmaris longus (PML) muscles of rhesus monkeys were transplanted, with or without anastomosis of the median nerve, to the nerve stump of the autograft. Because PML autografts revascularize spontaneously, vascular anastomoses were not performed. Muscle fibers regenerated in all autografts with neuroanastomosis, but in ... | 120,935 | [
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Antibodies to Candida species after operations on the large intestine: observations on the association with oral and faecal yeast colonization. | The occurrence of agglutinating and precipitating antibodies to Candida species was determined in 50 patients undergoing operations on the large intestine. The number of patients with oral or faecal yeast colonization and the amount of faecal colonization increased during the period after operation. No patient develope... | 120,986 | [
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A simplified, cost-effective approach to the diagnosis of pheochromocytoma. | Plasma catecholamines have been used for diagnosis and computerized tomography scanning for localization in 21 patients with proved pheochromocytoma. Blood catecholamines were obtained in 20 of the patients and were elevated significantly in every instance. Successful localization of the tumor was accomplished by excre... | 120,992 | [
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[Verification of nosocomial infection chains with Pseudomonas aeruginosa (author's transl)]. | With all 3 typing methods (sero, lyso, pyocin type) errors can arise. The pyocin test following heat curing can be expected to give the least erroneous results. This was demonstrated by a test of 200 non-selected strains which were grown within 4 weeks. The possibility exists that a single patient discharges several di... | 121,005 | [
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Effect of short-term administration of cyproterone acetate on the reproductive tract histology, ovarian and serum cholesterol contents of female monkey (Presbytis entellus entellus). | Short courses of cyproterone acetate, a compound with progestational and antiandrogenic activities were administered to normally cycling female monkeys to investigate into the effects of cyproterone acetate on the reproductive tract. In little earlier follicular stage 20 mg of the drug daily for 30 days increased the c... | 121,016 | [
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Cholesterol dynamics in macrophages implication for the bacteriology and pathology of leprosy. | M. leprae in the host multiplies abundantly in macrophages rich in cholesterol. Host-grown leprosy bacilli have an extremely high cholesterol content and in this respect they occupy a unique place among procariotic cells. M. leprae takes up cholesterol from the environment and it is not clear whether it can synthesize ... | 121,019 | [
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The chemotactic, phagocytic, and microbial killing abilities of primate polymorphonuclear leukocytes (PML). | Functions of polymorphonuclear leukocytes including chemotaxis, phagocytosis, and microbial killing were investigated in baboons (Papio cynocephalus), cebus monkeys (Cebus apella), and marmosets (Saguinus oedipus). Cells from a group of normal adult human volunteers were also studied for comparison. Polymorphonuclear l... | 121,031 | [
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[Current tests for the "in vitro" immunologic exploration in man]. | Several "in vitro" methods are developed to study cellular immunity as same as study of antibodies in humoral immunity exploration. The more used in human pathologics are the enumeration of thymus-derived (T) lymphocytes by the formation of nonimmune rosettes E with sheep erythocytes and bone marrow (B) lymphocytes by ... | 121,050 | [
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Critical density for protein-protein monoconjugation on a polysaccharide matrix. | The galactose binding toxin (RCAII) from Ricinus communis was affinity-immobilised at varying densities on a polysaccharide matrix and reacted with glutaraldehyde. The critical density below which inter-molecular cross-links were not formed was determined. At this density RCAII was monoconjugated to lysozyme. This appr... | 121,056 | [
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[Amino acid composition and chemical functional group modification of protease (TI-Ajl) inhibitor from Actinomyces janthinus 118]. | The amino acid composition of the protease (TI-Ajl) inhibitor from Actinomyces janthinus 118 has been determined. It was shown that the TI-Ajl, S-SI and plasminostreptin inhibitors of trypsin and subtilisin have a number of common features: number of double bonds, tryptophane and tyrosine residues, prevalence of the ac... | 121,060 | [
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Activity of precentral neurons during torque-triggered hand movements in awake primates. | In monkeys performing a handle-repositioning task involving primarily wrist flexion-extension (F-E) movements after a torque perturbation was delivered to the handle, single units were recorded extracellularly in the contralateral precentral cortex. Precentral neurons were identified by passive somatosensory stimulatio... | 121,062 | [
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[Some peculiarities of the kinetics of DNA structural transition after thermal jump registered by hyperchromic effect]. | Structural transition of DNA is characterized by complex optical kinetic curve. The kinetic version of Felsenfeld's method is used for estimation of concentrations of "denatured" AT- and GC-base pairs in DNA molecules, and the rate constants of the accumulation of "denatured" AT as well as GC pairs have been estimated.... | 121,149 | [
-0.1078972,
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0.7376736,
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... |
Resistance of Mycoplasma pneumoniae to macrolide and analogous antibiotics. | 1. The susceptibility of M. pneumoniae to antibiotics can be determined by the microtiter method. The adequate technique requires that the final volume of broth medium in a well is 0.2 ml and that the dilution is made after the parent solution of antibiotic in the test tube is dropped into a well every fifth wells. 2. ... | 121,168 | [
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0.335391,
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[Treatment with carbamazepine of epilepsy with behavioral trouble in mentally retarded children in a medicopedagogic institution (author's transl)]. | Thirty five mentally retarded girls, with epilepsy associated with behavioral troubles, were treated with carbamazepine in a medicopedagogic institution for 4 months to 7 years. Fifty percent got better, thirty percent showed a disappearance of the epileptic spells and 67% showed an aggravation of the EEG. Improvement ... | 121,194 | [
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0.2522436,
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In vivo activation of murine peritoneal macrophages by Nocardia water soluble mitogen (NWSM). | In vitro NWSM has been shown to be a B cell mitogen and a polyclonal activator. Although NWSM has been also shown to be adjuvant active in vivo, motogenicity and polyclonal activation are not observed when this fraction has been administered to mice. In contrast, the experiments reported here demonstrate that after in ... | 121,200 | [
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0.1706087,
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A comparison of four methods for the serotyping of group B streptococci. | Group B streptococci are implicated in a wide range of clinical conditions in human adults and neonates. The Group is subdivided into five serotypes Ia, Ib, Ic, II and III, which are differentiated on the basis of capsular polysaccharides. In the interests of epidemiology and efficiency a cheap, rapid method which is e... | 121,235 | [
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0.01267268... |
[Preventive action of phenylalanine on acute intoxication of ochratoxin-A]. | Ochratoxin-A, a mycotoxin causing kidney and liver damage, inhibits protein synthesis by competition with phenylalanine in the phenylalanyl-tRNA synthetase catalysed reaction. A dose of 0,8 mg ochratoxine per Mouse is 100% lethal within 24 hrs, when injected intraperitoneally. When phenylalanine is injected simultaneou... | 121,251 | [
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0.1708211,
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0.09... |
Phonation, emotion, cognition, with reference to the brain mechanisms involved. | Phylogenetic steps in the evolution of vocal communication have a bearing on the brain mechanisms involved in the emergence of human language and speech. A schema of the neuronal organization of voicing in a hierarchical manner is presented. At the lowest mesencephalic level the movements of the vocal apparatus are coo... | 121,283 | [
-0.1551134,
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0.5495113,
0.1939649,
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Non-Mendelian female sterility in Drosophila melanogaster: influence of aging and thermic treatments. III. Cumulative effects induced by these factors. | Crosses between various strains of Drosophila melanogaster may give rise to a female sterility of non-Mendelian determination. Reduced fertility is observed in females, known as SF females, bred from crosses between females of "reactive" strains and males of "inducer" strains. The reduced fertility of the SF females is... | 121,289 | [
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0.0067607,
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The ultrastructural features of laser trabeculopuncture and cyclodialysis. Problems related to successful treatment of chronic simple glaucoma. | Microexplosions induced by a Q-switched Nd:glass laser working above optical breakdown power density levels are able to destroy the inner wall of Schlemm's canal and to tear open both the supraciliary and suprachoroidal space. Furthermore, the ciliary muscles bundles may be disrupted, becoming subsequently permeable to... | 121,373 | [
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0.03882334,
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PSRO impact: are the statements valid? | The generation of PSRO impact statements cannot simply be a "fill in the formula" routine. A health care system is not a simple environment, and narrow approaches to documenting change usually will not suffice. Instead, one would hope that future PSRO impact studies will take into consideration at least the concerns di... | 121,381 | [
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0.0240799... |
[A control trial of home I.P.P.B. therapy in patients with chronic obstructive respiratory insufficiency. Protocol and state of the study (author's transl)]. | Because a previous retrospective study did not allow any conclusion as to the efficacy of home IPPB therapy in patients with chronic airflow obstruction, a control trial has been started. The protocol includes definition of patients, modalities of treatment, criteria for evaluation. Among criteria for a patient to ente... | 121,483 | [
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0.2322089,
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0.1462757,
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0.16208... |
[Neurohormonal regulation of male gonad function]. | In a survey the neurohormonal regulatory mechanisms are discussed which control the incretory and spermiogenetic function of the testicles in adulthood. The central position of LH-RH and the factors influencing its secretion, the negative feedback between the testicular hormones including inhibin and the hypophyseal go... | 121,496 | [
-0.117661,
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... |
[Non-amyloid nephrotic syndrome: first isolated manifestation of a kappa light chain myeloma (author's transl)]. | The authors describe a case which demonstrates that nephrotic syndromes occuring during the course of a myeloma are not always of the amyloid type. They emphasize the possibility of a dysglobulinemia being involved in a glomerular nephropathy syndrome, especially when there are histological lesions of a glomerulosclero... | 121,516 | [
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0.197024,
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0.293996,
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0.0... |
Taurine in development and nutrition. | Taurine is an amino acid that is widely distributed in the fluids and tissues of man. In mammals, taurine is a major end-product of methionine metabolism. Taurine is found in most mammalian tissues but is only present in trace amounts in many plants. During fetal development of the brain in man and other mammals taurin... | 121,570 | [
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0.2185253,
0.422456,
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... |
First tuberculosis prevalence survey in KwaZulu. | The results of a prevalence survey undertaken during 1974 are presented. A stratified 3-stage sampling technique was used to select 3 789 people from 10 randomly chosen sites in KwaZulu. One Heaf test and 2 Mantoux tests were performed on each of 1 769 children under 18 years of age, of whom 28,7% were found to have BC... | 121,637 | [
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Role of serum factors and adherent cells in cloning of human T lymphocytes in agar culture. | In the presence of serum, 2-mercaptoethanol-treated bovine serum albumin enhances T cell colony formation as does 2-mercaptoethanol. The factor only partially substitutes for FCS, but neither for the mitogen phytohemagglutinin nor for conditioned medium derived from cultures of adherent cells. | 121,677 | [
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0.5719915,
0.1988196,
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Jaundice in preterm infants with hypoxia of various severity. | Maximum serum bilirubin concentration and the possible influencing factors were studied in three groups of preterm infants suffering from hyaline membrane disease. The groups were selected according to the severity of hypoxia, estimated on clinical grounds. It was found that the severity of hypoxia per se did not influ... | 121,679 | [
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0.04242684,
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Classification of hereditary cataracts in children by linkage analysis. | A total of 12-different types of hereditary cataracts have been positively assigned to the gene map. They are located on autosomes as well as on the X chromosome. This establishes several kinds of cataracts as distinct diseases caused by different mutations. In selected cases the information may be helpful for prenatal... | 121,767 | [
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0.2208252,
0.1790359,
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Distribution of blood groups and secretor status in schistosomiasis. | Urine and stool specimens from 425 school children in Swaziland were examined for evidence of Schistosoma mansoni or Schistosoma haematobium infection. Concurrently, saliva collections were analysed for ABH secretory ability and blood samples were typed for ABO, Rh and Lewis groups. Among individuals infected with S. m... | 121,770 | [
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0... |
The longitudinal approach to the pathogenesis of respiratory disease. | Longitudinal observations were made of a well-defined population of children at a day care center in an investigation of the pathogenesis of infections due to respiratory syncytial virus (RSV) and Mycoplasma pneumoniae. A single RSV infection induced a modest but significant degree of resistance to further RSV infectio... | 121,783 | [
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Fukuyama type congenital muscular dystrophy as a natural model of childhood epilepsy. | Fukuyama type Congenital Muscular Dystrophy, inherited autosomal-recessively, is characterized by muscular dystrophy associated with severe mental retardation and epileptic convulsions. By examining 56 cases, followed for more than three years, 75 EEG records from 40 patients and visual evoked potentials from 11 patien... | 121,866 | [
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0.2839245,
0.09975018,
0.2114397,
0.3621707,
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Adult type GMl-gangliosidosis: a complementation study on somatic cell hybrids. | Two adult siblings with progressive pyramidal and extrapyramidal lesions, and generalized muscle atrophy had a profound deficiency of beta-galactosidase in all the cells and body fluids examined. Neuraminidase activity was normal in fibroblasts. The fused fibroblasts of infantile GMl-gangliosidosis and each of these ad... | 121,869 | [
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0.185279,
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Synthesis and studies of transferrin. | Combination of the usual techniques yielded 70-80 p.c. pure apo- and iron-transferrin preparations, whose analysis revealed the presence of antigenically identical transferrin fractions differing from one another in respect of electrophoretic motility and sedimentation contrast. No similar modifications of transferrin ... | 121,874 | [
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... |
13C NMR analysis of methionine sulfoxide in protein. | The 13C epsilon NMR signal of methionine sulfoxide is 22.6 ppm downfield from that of methionine. This affords a method by which the extent of methionine oxidation can be determined in intact protein. We demonstrate the utility of this approach with beta-galactosidase enriched with 13C in its methionine methyls. | 121,887 | [
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0.09999946,
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Comparative evaluation of some methods for detection of M. pneumoniae antibodies. | Various methods of detection are available for measuring antibodies specific to M. pneumoniae. We examined over 600 sera of patients with clinical diagnosis of M. pneumoniae infection using complement fixation (CF) test. 91 gave positive reaction and were therefore selected for a comparative analysis with other methods... | 121,958 | [
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... |
[Analysis of flexion energy variations of a human red blood cell, of ellipsoid form, in the process of deformation imposed by turbulent tangential flux]. | The purpose of the present, morphological analysis is to recognize a functional connection between shear stress tau, which Human Red Cells, treated with glutaraldehyde, are subjected and their energy of bending (U), during the shape transition, turbulent shear-flow dependent, under the hypothesis of "isoareal" transfor... | 121,961 | [
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0.1781294,
... |
[Lysine deficiency and carnitine biosynthesis in the rat]. | Male rats weanling fed 20% gluten diet for 90 days of demonstrate to have about one-third lower level of carnitine per gram of skeletal muscle and heart muscle than the group which received the same diet supplemented with 1% of lysine. The carnitine level of the liver, however, was significantly higher in the unsupplem... | 121,965 | [
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0.1429626,
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0.1189802,
0.03543328,
0.1822892,
-0.07058869,... |
Effects of parasitic infections in pregnant women. | This review focuses on the parasitic diseases which occur frequently in the tropics and which affect pregnant women. Clinical disease of the mother during pregnancy, vertical transmission of parasites and transplacental passage of soluble parasitic antigens are discussed in relation to their immunopathological signific... | 121,975 | [
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0.3914969,
-0.195198... |
A comparative study on the pretreatment methods for the cultivation of Mycobacterium tuberculosis on LJ medium. Part I. | The sputa of 303 cases who were admitted at Ojha Sanitaurium Karachi were studied for comparing the efficacy and reliability of the three pretreatment methods including the standard method, and those recommended by Nassau (1958) and Becker (1916). Out of the total 223 cases were found to be positive after cultivation o... | 121,981 | [
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0.09117837,
0.06265696,
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0.06... |
[Interaction of cimetidine and metoclopramide on the lower esophageal sphincter in man]. | The purpose of this study is to evaluate the effect of Cimetidine and Metoclopramide on human lower esophageal sphincter (LES) pressure. Intravenous Metoclopramide in a bolus injection (0.3 mg/Kg or a maximal dose of 20 mg) produced an increase of LES pressure from 20,8 +/- 3,1 mmHg to a peak response of 42,0 +/- 5,0 m... | 121,985 | [
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0.3474556,
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0.1210814,
... |
[Carbon dioxide laser and gynaecological surgery (author's transl)]. | The authors describe their one year's experience with a CO2 Laser in gynaecology. They emphasise the ease of use of the equipment. Three major divisions of gynaecology can benefit from the CO2 Laser: benign or precancerous lesions of the vulva and of the vagina, dysplasia of the cervix, surgery of the fallopian tubes. ... | 121,998 | [
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0.3257526,
0.2880812,
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... |
Modulation of erythropoietin concentrations by manipulation of hypercarbia. | The present studies were done to determine whether preventing the respiratory alkalosis, which is known to occur with acute "hypoxic" stimuli, would lead to alterations in plasma concentrations of erythropoietin (Ep). Rats were subjected to two acute stresses, hypoxia and blood loss, separately and in combination, with... | 122,167 | [
-0.1298406,
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0.09617926,
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-0.2057758,
0.01932306,... |
Aldose reductase inhibition: studies with alrestatin. | Studies with the aldose reductase inhibitor alrestatin in animal models have suggested that the sorbitol pathway may be of etiologic significance in the pathogenesis of peripheral neuropathy in diabetes. In normal subjects and in highly selected diabetic patients with severe peripheral neuropathy, alrestatin given eith... | 122,298 | [
-0.1890686,
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0.05556237,
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0.5539736,
0.1100829,... |
Serum immunoconglutinin levels in healthy subjects, malaria nephrosis and other conditions. | Serum immunoconglutinin (I-K) levels were estimated and compared in 189 normal school children, ninety blood donors, eight-seven nephrotic children, twenty-eight nephrotic adults, twenty-five falciparum malaria children and 126 miscellaneous patients. Low levels (1/32 or less) were recorded in 75.1% of normal school ch... | 122,318 | [
-0.1784934,
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0.008432865,
0.1507773,
0.01727356,
0.1111622,
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... |
Roentgenological measurement of skull size in Nigerian children. | The maximal internal length L, height H, and width W, were measured on normal A.P. and lateral skull radiographs on 352 Nigerian children whose age range was from birth to 12 years. The distance between the necks of the mandibles M, was also measured. Based on the above measurements the Cronqvist cranial indices (Formu... | 122,321 | [
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0.2609126,
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0.4852776,
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0.03492795... |
Haemoglobin DIbadan in a haemoglobin S endemic population. | Haemoglobin DIbadan (beta 87 threonine leads to lysine) was originally found in Ibadan, an area with a high incidence of sickle cell haemoglobin (HbS). Since haemoglobin D and S are indistinguishable by most common conventional methods, the geographical coincidence of the two haemoglobin poses a serious screening probl... | 122,322 | [
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0.09653422,
0.3112153,
0.4530506,
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... |
A double-blind comparative study of cimetidine and placebo in adult Nigerian duodenal ulcer patients with special reference to gastroduodenal mucosal morphology and intestinal bacterial activity. | Twenty-seven adult Nigerian patients with endoscopically proven active duodenal ulcers have received in a double-blind trial either the histamine H2 - receptor antagonist cimetidine 1g daily or placebo tablets of identical appearance for 4 weeks. Fifty-six per cent of the cimetidine patients and 18% of those receiving ... | 122,333 | [
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0.189369,
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Principles of intravenous nutrition. | In my view intravenous feeding represents a substantial advance in the management of critically ill patients. It is no longer tenable that patients should die as a result of complications of malnutrition simply because they cannot or are unable to take adequate oral nutrition. Intravenous feeding is a challenge both in... | 122,354 | [
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0.1359334,
0.1090076,
... |
Inhibition of gonadotropin and prolactin release by dopamine: effect of endogenous estradiol levels. | The influence of endogenous estradiol (E2) levels on gonadotropin and PRL sensitivity to dopamine (DA) infusion (4 micrograms/kg/min) was assessed at different stages of the follicular phase of the menstrual cycle. Basal LH and FSH levels were comparable in day 2 and day 12 subjects, and despite a 4-fold increase in E2... | 122,409 | [
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0.02740488,
0.3570599,
0.007425922,
0.1482016,
-0.066389... |
Progesterone induced acute release of prolactin in estrogen primed ovariectomized women. | Progesterone (10 mg) administered intramuscularly induces a concurrent release of prolactin as well as gonadotropin in estrogen-primed women. The time course of pituitary release of all three of these hormones appears to include a latent phase of 4 hrs and is maintained for at least 5 hrs. It is considered that this ef... | 122,417 | [
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0.178492,
0.08178331,
... |
The relationship of changes in serum estradiol and progesterone during the menstrual cycle to the thyrotropin and prolactin responses to thyrotropin-releasing hormone. | The responses of serum TSH and PRL to TRH (500 microgram) were studied in normal young women in the early follicular, periovulatory, and midluteal phases of the menstrual cycle in order to examine the relationship of these responses to the levels of estradiol relationship of these responses to the levels of estradiol (... | 122,427 | [
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0.03508033,
0.05915461,
0.1655024,
0.110808,
0.004209818,
0.0589893... |
[Extreme psychogenic shock states in childhood]. | An attempt is made in this paper to describe a syndrome consequent upon extreme psychogenic shock situations, which has been observed in a number of children. This syndrome is characterized by panic, flight, and anxiety during the actual event, which are followed by a relatively prolonged period of exclusion from consc... | 122,472 | [
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-... |
[Follow-up studies of high-risk children at the time of entering school in comparison with a normal group]. | Somatic, neurological and psychological follow-up examinations performed on 54 high-risk children for school enrollment gave no significant differences in comparison with a randomized equal number of normal control children, with regard to physical development and maturation as indicated by carporadiograms. So far as n... | 122,486 | [
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0.423366,
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0.2718496,
0.03462458,
... |
[Neurogenic disorders of bladder emptying in children]. | Disturbed micturition of the neurogenic type is found in children suffering from spinal tumors and anomalies of the vertebral column. The most frequent cause is the so-called myelomeningocele. Myelodysplasia can occur in 1-2 out of every 1,000 new-born babies. Operative treatment is available today (closing the celes i... | 122,496 | [
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... |
[Initial reports on experiences in working with special groups in child day care centers]. | A decisive condition for advancement at an early stage is the detection of physical damage. In this connection the GDR Ministry of Public Health has published guidelines for the establishment of special groups for infants suffering from physical damage, at ordinary creches (Verfügungen und Mitteilungen 15/1976). In 197... | 122,506 | [
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0.08940348,
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Analysis of plasmid deoxyribonucleic acid in a cariogenic strain of Streptococcus faecalis: an approach to identifying genetic determinants on cryptic plasmids. | Streptococcus faecalis strains ND539 and OG1 have been previously shown to be cariogenic in gnotobiotic animals. Deoxyribonucleic acid analyses have revealed the presence of a single 26-megadalton plasmid designated pAM539 in the former strain, whereas the latter strain was found to be plasmid-free. By gene transfer ex... | 122,512 | [
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0... |
Influence of R-plasmid RP1 of Pseudomonas aeruginosa on cell wall composition, drug resistance, and sensitivity to cold shock. | R-plasmid RP1 was transferred to Pseudomonas aeruginosa cells, as indicated by their resistance to carbenicillin, ampicillin, cephaloridine, kanamycin, and tetracycline, and by the presence of a periplasmic beta-lactamase. The wild-type cells (RP1-) were lysed by ethylenediaminetetraacetic acid but not by ethylene-glyc... | 122,523 | [
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0.2566097,
0.2927432,
0.4381576,
0.2330984,
-0.08666448,
... |
Vitamin E deficiency and seizures in animals and man. | Study of 100 children with grand mal convulsive disorders and 100 medically healthy children of matching age showed significantly lower plasma levels of vitamin E in the former (means 632.2 +/- 17.3 and 822.5 +/- 21.8 micrograms/dl respectively; p less than 0.001). This finding accords with the ability to prevent seizu... | 122,540 | [
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0.2547979,
0.02545688,
-0.... |
Hormonal regulation of trehalose metabolism in the blowfly Phormia Regina Meig.: effects of cardiacectomy and allatectomy at the subcellular level. | 1. Kinetic properties of adult Phormia fat body glycogen synthetase were studied and compared to other animals. The KM for UDPG is 2.82 mM, decreasing to 0.58 mM in the presence of G-6-P. 2. The specific activity of fat body glycogen synthetase shows a reduction of 30% within 2 days after allatectomy. 3. Fat body T-6-P... | 122,562 | [
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0.6131184,
0.008729098,... |
Purine nucleoside phosphorylase from bovine liver. | 1. Purine nucleoside phosphorylase (purine nucleoside:orthophosphate ribosyltransferase, E.C. 2.4.2.1) from liver of cattle, Bos taurus, was purified to homogeneity. Some properties of the enzymes from three different bovine tissues were compared and discussed. 2. The enzyme has a molecular weight of 83,000, a sediment... | 122,568 | [
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0.06941564,
0.02934215,
0.5340528,
0.3453528,
-0.234771... |
Glycolytic end products of the adult dog heartworm, Dirofilaria immitis. | 1. Adult dog heartworms remained alive and motile for 24 hr without oxygen present and with only glucose available as a substrate. 2. Lactate accounted for 55% of the carbon from the 1-14C-glucose utilized in 1 hr and 14CO2 for 1.9%. 3. Only traces of 14C were found in glycogen and no net accumulation of acetate was de... | 122,581 | [
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0.3296452,
0.04211795,
0.1451976,
0.4057294,
-0.10037... |
Growth of school children with polychlorinated biphenyl poisoning or yusho. | In 1968, a mass poisoning due to polychlorinated biphenyls or yusho occurred in Japan. It was reported that poor growth in school children with yusho was observed 1 year after the poisoning. This study was intended to ascertain whether or not the unfavorable effect of the polychlorinated biphenyl poisoning on growth am... | 122,586 | [
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0.223159,
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0.... |
The effect of luteinizing hormone releasing hormone (LHRH) antiserum administration on gonadotropin secretion in the rhesus monkey. | Single iv injections of a rabbit antiserum to synthetic LHRH promptly suppressed serum LH and FSH concentrations in ovariectomized rhesus monkeys. Gonadotropin levels remained depressed for 10-21 days, the approximate duration of enhanced LHRH binding activity in the circulation. Doses of LHRH antiserum sufficient to r... | 122,596 | [
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0.09734272,
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... |
Effect of progesterone and its 5 alpha-reduced metabolites on gonadotropin levels in estrogen-primed ovariectomized rats. | In an effort to determine whether the metabolic conversion of progestrone may be important in the feedback effects of this steroid, serum LH and FSH levels were measured after administration of progesterone, 5 alpha-dihydroprogesterone or 3 alpha-hydroxy-5 alpha-pregnan-20-one to estrogen-primed ovariectomized rats. A ... | 122,598 | [
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0.07027894,
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0.1508469,
0.3238454,
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... |
Miconazole in coccidioidomycosis. | The epidemiology of Coccidioides immitis is described with respect to annual infection rates and differing ethnic susceptibilities to the infection. A trial of miconazole in infected mice produced 100% survival in conditions which normally kill 100% of animals, probably by drastically reducing the rate of fungal multip... | 122,639 | [
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0.5576006,
0.1216875,
0.3874864,
-0.01698122,... |
Therapy for deep mycoses: an introduction. | A classification of mycoses, depending upon the depth of penetration of the organism is discussed, as is the need to distinguish the true from the 'pseudo' mycoses. The development of antifungal agents is described from the first antibiotics to amphotericin B and 5-fluorocytosine. Attention is particularly focussed on ... | 122,641 | [
-0.1354499,
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0.005764293,
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0.1542067,
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0.02280301,
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0.03734617,
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0.1844897,
0.1854009,
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0.2285399,
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0.2501473,
0.3249682,
0.2632102,
0.06855988,
-0... |
Clinical and experimental evidence on miconazole for the treatment of systemic mycoses: a review. | Intravenous treatment with miconazole brought about the recovery of 90% of patients with gastrointestinal or systemic candidosis. Miconazole given by the same route has also been found effective in the treatment of cryptococcosis, coccidioidomycosis, and paracoccidioidomycosis. Cryptococcal and coccidioidal meningitis ... | 122,647 | [
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0.08683603,
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0.128405,
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0.3098031,
0.19333,
-0.... |
Penicillamine treatment of rheumatoid arthritis: relationship of proteinuria and autoantibodies to immune status. | Thirty-seven patients were studied before and during treatment with respect to immune status, clinical response and development of adverse effects and autoantibodies. The baseline immune status was not predictive in terms of the above features, apart from the fact that the group of 7 patients developing proteinuria had... | 122,657 | [
0.1020665,
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0.06739948,
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0.01434831,
0.08170446,
0.3208269,
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0.2329674,
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0.3543169,
0.1484343,
0.07632644,
0.01337693,... |
The effect of penicillamine on growth as height in juvenile chronic polyarthritis. | When the disease state improves during penicillamine therapy, resumption of growth occurs; if activity persists despite therapy, the expected fall-off in growth due to active Still's disease continues. Penicillamine does not interfere with the growth spurt after withdrawal of corticosteroid therapy or with the maintain... | 122,658 | [
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0.1480093,
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0.08825577,
0.1032302,
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0.1344962,
0.2606102,
-0.132947,
-0.0802426,
-0.... |
[A technic to prepare fixed ground sections for a quantitative microradiography study of the dentin]. | The preparation of ground sections for the quantitative microradiographic study of dentine was carried out either by hand or by machine using a new technique of fixing the sections to the holder by a soluble adhesive. After setting up a method of control for the plano-parallelism of the sections, the times of preparati... | 122,698 | [
0.01523525,
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0.1882645,
0.2741586,
0.05231578,
-0.188988,
0.24... |
Lithium metabolism and intracellular electrolytes. | Lithium chloride was administered orally to swine and two different types of sheep, HK and LK. There was a pre-lithium 16-fold variation in intracellular sodium (LK greater than HK greater than swine) and a 6.5-fold variation in the intracellular potassium (swine greater than HK greater than LK). Collected plasma and e... | 122,706 | [
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0.3264867,
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0.2017781,
0.02434472,
-0.05445026,
0.2136901,
0.2798851,
0.02612... |
Disulfiram alters dopamine metabolism at sites in rat's forebrain as detected by push-pull perfusions. | The effect of tetraethylthiuramdisulfide (disulfiram) on the catabolism of dopamine within discrete regions of the brain was investigated in the unrestrained rat. After a guide cannula had been implanted stereotaxically, a given subcortical site was radiolabeled with 14C-dopamine (DA) by microinjecting 2.0 mu Ci in 2.0... | 122,719 | [
-0.03151778,
0.2537759,
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0.04681702,
0.003139712,
0.2600405,
0.07107634,
0.03288111,
0.1690121,
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0.1173132,
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0.05199181,
0.368863,
0.145175,
0.04112355,
0.3338704,
-0.05412089,
... |
Biological activity of neurotensin and its C-terminal partial sequences. | A hypothalamic tridecapeptide, neurotensin, and its C-terminal partial sequences down to the dipeptide were synthesized. These peptides were assayed for smooth muscle contracting and blood pressure lowering properties using preparations of isolated stomach fundus, uterus and duodenum of the rat, isolated guinea pig ile... | 122,721 | [
-0.1068113,
-0.131604,
-0.461828,
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0.5036739,
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-0.05229172,
0.2935167,
0.02910747,
0.03462357,
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0.2299482,
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0.01290416,
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0.2099469,
0.09348405,
0.1437583,
0.06776685,
0.2576634,
-0.1027764,
... |
Determination of group specific component phenotypes in dried bloodstains by immunofixation on cellulose acetate. | Group specific phenotypes in dried bloodstains can be rapidly and reliably determined by immunofixation on cellulose acetate membranes. Up to 16 samples, can be analyzed simultaneously in less than 60 min, and the cellulose acetate electrophoretogram is retained as a permanent record. | 122,746 | [
-0.08814874,
0.4278337,
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-0.1810422,
-0.04767492,
-0.08434404,
-0.2024487,
0.07681312,
0.1514578,
0.2579823,
0.02379539,
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0.2200815,
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0.03479927,
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0.2982214,
0.3840585,
0.07348698,
-0.1920938,
... |
Influences of clinical factors on marginal adaptation and residual mercury content of amalgam. | Clinical factors affecting residual mercury and marginal adaptations of amalgam restorations in a private practice environment were investigated. Findings, converted to ridit values, indicated that influencing factors are the training level of the dental assistants, type of amalgamator, accuracy of the timing device, a... | 122,832 | [
-0.2919031,
0.4927267,
-0.1178266,
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0.2327775,
0.01563766,
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0.2628561,
0.077258,
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0.02106798,
-0.3604176,
0.03958073,
0.03469121,
0.003181618,
0.14... |
Parotid saliva enzymes in Down's syndrome. | The parotid saliva in persons with Down's syndrome was analyzed for three enzymes: acid phosphatase, nonspecific esterase, and amylase. The results have shown a statistically significant elevation of esterase activity in persons with Down's syndrome whereas no statistical differences were observed with the other enzyme... | 122,833 | [
-0.0834624,
-0.1989644,
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-0.1583807,
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-0.2243909,
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0.05578852,
0.3256023,
0.2132471,
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-0.07134987,
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-0.3913572,
-0.0881489,
0.05950055,
-0.1053492,
0.165977,
0.044705,
-0.1097489,
... |
Patent ductus arteriosus complicating the respiratory distress syndrome in preterm infants. | In 46 preterm infants with RDS the patency of the ductus arteriosus was established by single film aortography or by clinical diagnosis and confirmation at surgery. The estimated left-to-right shunt through the PDA by aortogram correlated well with the heart size and the clinical diagnosis of heart failure. In 14 infan... | 122,840 | [
0.1470507,
0.02548861,
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0.04341631,
0.2388915,
0.1450403,
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0.4240142,
-0.01150788,
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-0.05974215,
-0.06178059,
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-0.6377568,
0.3583848,
-0.03685377,
-0.4216312,
0.3565707,
-0.2965827,
0.01637356,
... |
Surgical aspects of regional myocardial blood flow and myocardial pressure. | The surgical technique of cardiopulmonary bypass with either an empty beating or an empty fibrillating ventricle produces marked changes in the regional blood flow and oxygen demand of the left ventricle. This paper describes the changes which occurred in the regional perfusion of both the normal and the hypertrophied ... | 122,850 | [
-0.3948561,
0.07345458,
-0.270797,
-0.1321359,
-0.1628311,
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0.1057955,
0.02927131,
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-0.01392876,
-0.1673116,
0.4304086,
-0.07499092,
0.1874819,
0.1725173,
-0.1507722,
... |
Effects of streptozotocin on glucose metabolism, insulin response, and adiposity in ob/ob mice. | To determine whether hyperglycemia in the obese hyperglycemic (ob/ob) mouse is related to enhanced activity of the pancreatic beta cell, streptozotocin (175 mg/kg) was injected into lean and ob/ob mice at 8 wk of age. The influence of this injection upon glucose metabolism, adipose cellularity, pancreatic morphology an... | 122,852 | [
0.03362174,
-0.2996503,
-0.5088107,
-0.005027856,
0.01226663,
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0.197615,
0.273694,
-0.1153049,
0.1951,
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0.144651,
0.01310492,
0.5051429,
0.3628504,
0.2147508,
0.1366476,
0.2778982,
-0.05624731,
-0.21... |
Train-of-four nerve stimulation in the management of prolonged neuromuscular blockade following succinylcholine. | Four patients, all possessing an atypical form of plasma cholinesterase, developed prolonged paralysis following succinylcholine administration. The clinical management of all four cases was facilitated by monitoring the train-of-four stimulus. All patients showed marked "fade" of the train-of-four ratio, the initial r... | 122,883 | [
-0.1237911,
0.2279872,
-0.2045886,
-0.5785007,
-0.1659045,
-0.2709818,
-0.2275161,
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0.07803806,
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0.32708,
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0.0222046,
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0.08604317,
-0.1426923,
-0.06033595,
0.1381296,
0.1352842,
0.05867717,
... |
Managing the complications of plasma cell myeloma. | Management of some diverse complications of plasma cell myeloma is reviewed with respect to prevention when possible and prompt treatment when necessary. A series of 102 patients from the Duke University Medical Center was surveyed to ascertain the approximate frequency with which renal failure, hypercalcemia, infectio... | 122,891 | [
-0.3156554,
-0.06896389,
-0.1554675,
-0.2659923,
-0.147154,
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0.00184015,
0.09639036,
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0.1342373,
0.1787797,
0.2346031,
-0.2161525,
-0.0413563,
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0.1763927,
0.1002586,
0.3114476,
-0.07161547,
0.1211926,
0.09177579,
0.003608101,... |
[The angiographic demonstration of a primary sarcoma of the pulmonary artery]. | Following the findings of a primary sarcoma of the pulmonary artery and its angiographic demonstration, a search was made of the literature for this rare condition. Angiography is usually performed because a pulmonary embolism is suspected. It is best to inject contrast medium into the right atrium or ventricle. If an ... | 122,957 | [
-0.3624382,
0.08278944,
-0.2043542,
-0.2484334,
0.1009704,
-0.2269527,
-0.3065193,
-0.09956113,
-0.305417,
0.0991817,
0.1776061,
0.2497364,
-0.07781192,
-0.3951991,
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-0.2686364,
0.1574445,
0.2209223,
0.1847817,
0.4919378,
-0.01400348,
-0.09600338,
... |
Amyloid in the aged heart: frequency and clinical significance. | Cardiac amyloid accumulation is a common autopsy finding in elderly persons, the frequency increasing with each advancing age decade. In most cases the deposits are microscopic, confined to the atrial subendocardium, and of dubious significance. In a few cases, however, there is much more extensive cardiac involvement,... | 122,982 | [
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-0.2255408,
0.1681697,
0.2845905,
-0.09436122,
-0.002111485,
0.353068,
-... |
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