title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Prevalence of Dictyocaulus viviparus infection in Rocky Mountain elk in Teton County, Wyoming. | Dictyocaulus viviparus infections in Rocky Mountain elk (Cervus canadensis of Teton Countywere surveyed by fecal analyses during spring, summer and winter and by fecal analyses and necropsies during fall hunting seasons, 1968-1973. Prevalance of the lungworms was relatively high: 32-70% during the spring; slightly low... | 123,012 | [
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Blood flow velocity in the carotid artery as a measure of myocardial contractility. | An attempt was made to derive a useful noninvasive index to evalute a change in myocardial contractile state using transcutaneous Doppler flow-velocity curve from the carotid artery. In 5 mongrel dogs and in 43 patients with various heart disease, Doppler flow velocity curves were obtained from the ascending aorta intr... | 123,016 | [
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Hereditary carnitine deficiency of muscle. | An eight-year-old boy with slowly progressive muscle weakness was found to have Oil red O positive vacuoles in predominanty type i muscle fibers. Subsequent studies demonstrated markedly reduced skeletal muscle carnitine (0.24 mumoles per gram; normal 1.64 to 3.34). Serum carnitine was normal. Although both parents wer... | 123,043 | [
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Persisting changes in sensory and motor activity of a muscle following its reflex activation. | A study was made to see if contractions induced by reflex action were followed by an elevation in muscle afferent activity comparable to the post-contraction sensory discharge (PCSD) that occurs after stimulation of the ventral roots. In lightly anesthetized cats, extension reflexes of the triceps surae muscle in the o... | 123,059 | [
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Continuous positive airway pressure breathing (CPAP). Apparatus for use in neonates or adults. | CPAP is a technique of respiratory care which was originally described in the management of the respiratory distress syndrome of the newborn and later in the post operative management of the cardiac infant following surgery. It has potential value in the respiratory management of older children and adults. Apparatus is... | 123,128 | [
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Influence of antibody-mediated immune suppression on clinical, viral, and immune responses to swine influenza infection. | Antibody-mediated immune suppression occurred when newborn pigs with naturally acquired passive antibody were exposed to seine influenza virus. Frequency and relative ease of recovery of virus from nasal secretions were inversely related to the concentration of specific passive antibody existing at time of exposure. Se... | 123,140 | [
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Glycolytic enzymes in resting spores and vegetative mycelia of Entomophthora pyriformis. | Specific activities of 14 enzymes of the Embden-Meyerhof-Parnas and pentose phosphate pathways were determined in extracts of resting spores and vegetative mycelia of Entomophthora pyriformis. All these enzymes were detected in mycelial extracts, whereas only nine were detectable in resting spore extracts. Activities o... | 123,167 | [
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Precursors of sudden coronary death. Factors related to the incidence of sudden death. | Precursors of sudden death were sought in men--1838 civil servants in Albany, New York, and 2282 residents of Framingham, Massachusetts--under continuous surveillance for 16 years. In men 45-74 years old there were 234 deaths attributed to coronary heart disease (CHD) of which 109 occurred within one hour of onset of s... | 123,182 | [
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Experimental hyperosmolar diabetic syndrome. Ketogenic response to medium-chain triglycerides. | The clinical features of the experimental hyperosmolar diabetic (EHD) rat model resemble those seen in the human syndrome--extreme hyperglycemia without ketoacidosis is common to both. The absence of ketoacidosis in the syndrome has been ascribed to both substrate (free fatty acid) deficiency and to interference with h... | 123,210 | [
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Changes in the glutathione thiol-disulfide status of Neurospora crassa conidia during germination and aging. | Improved methods were developed for the determination of reduced glutathione (GSH), glutathione disulfide (GSSG), and protein-glutathione disulfide (PSSG) and applied to determine the glutathione status at various stages of the asexual life cycle for the band strain of Neurospora crassa. The GSH-GSSG ratio in freshly h... | 123,243 | [
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Percutaneous absorption on the relevance of in vitro data. | The use of in vitro preparations of human skin to study percutaneous absorption is widespread. Yet, up to the present time, little has been done to systematically validate this model and demonstrate the extent to which it mimicks in vivo absorption. In this study, the permeability of 12 organic compounds has been eva... | 123,263 | [
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Transfection of Escherichia coli spheroplasts. V. Activity of recBC nuclease in rec+ and rec minus spheroplasts measured with different forms of bacteriophage DNA. | The in vivo activity of the recBC nuclease was assayed by transfection of isogenic rec+ and rec minus spheroplasts with bacteriophage DNA of various origin and structure. The results indicate that the recBC nuclease can limit transfection at several stages during the production of an infective center; such limitations ... | 123,277 | [
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Non-uniform myocardial blood flow caused by stellate ganglion stimulation. | The blood flow through the anterior wall of the left ventricle has been studied during electrical stimulation of the left stellate ganglion of anesthetized dogs. The flow was continuously monitored by heated cross-thermocuple. Ganglion stimulation caused a significant increase in the flow through the outer half while p... | 123,285 | [
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Tetralogy of Fallot with atresia of the left pulmonary artery: surgical repair using a homograft aortic valve. | Two cases of tetralogy of Fallot with unilateral absence of the left pulmonary artery are presented. Both patients required a valve-retaining homograft because of severe pulmonary valve incompetence following previous surgical correction. This uncommon anatomic variant presents special surgical problems, as pointed out... | 123,292 | [
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[The inhibition of various bacterial proteinases with natural proteinase inhibitiors(author's transl)]. | Proteus mirabilis, citrobacter intermedius, staphylococcus aureus haemolyticus and staphylococcus albus produce extracellualr proteinases with maximum activity at pH 7.8. These proteinases are inhibited practically completely by human and animal blood serum. This inhibitory activity of human serum is caused by alpha2-m... | 123,295 | [
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[Osteoplastic epitympanotomy and the pathology of the middle ear. Part 2: The microstructures of the epitympanum and their significance concerning the pathology of the retrotympanal spaces (author's transl)]. | The two goals of osteoplastic trepanation of the middle ear spaces are first a direct inspection of the main areas of pathologies within the epitympanum and secondly a better understanding of the infected middle ear diseases through careful preparation and exposure of the pathologic processes. A new way of approval cou... | 123,299 | [
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[The effect of various antibiotics on the mixed flora of the maxillary sinus in sinusitis(author's transl)]. | The effect of four frequently used antibiotics on the germs of the sinus maxillaris was studied. For this purpose germs of the sinus max. rinsing fluid, got from 127 patients, were cultured under nearly the same physical and chemical conditions which can be expected in the sinus itself. Each antibiotic substance was st... | 123,303 | [
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Echocardiographic and electrocardiographic criteria for diagnosing left atrial enlargement. | Electrocardiographic criteria for left atrial enlargement (LAE) were evaluated in a group of 100 patients with a wide spectrum of cardiovascular diseases and compared with the echocardiographic measurement of left atrial dimension (LAD). Data analysis showed a high degree of correlation between the echocardiographic me... | 123,358 | [
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[Laws of substrate supply, of cell kinetics and of therapy mechanisms in the intercapillary region of cancer tissue]. | Up to now, the microtopography of glucose and O2 concentration in the intercapillary region of tumour tissue has been determined under the simplifying assumption that substrate consumption is constant up to the periphery of the envisaged cylindrical space around a capillary. The general diffusion field equation present... | 123,396 | [
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Changes of sodium transport in erythrocytes of the maturing rabbit. | The red blood cells of New Zealand white rabbits have a low sodium and high potassium content. As the animals mature, the sodium concentration rises and the potassium content falls; studies of red cells from a group of five young and five mature animals revealed a highly significant increase of cell sodium with age tha... | 123,417 | [
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Pulmonary microembolism associated with massive transfusion: I. Physiologic effects and comparison in vivo of standard and dacron wool (swank) blood transfusion filters in its prevention. | Pulmonary microembolism of microaggregates associated with massive blood transfusion may be a cause of post-traumatic pulmonary embolism. The purpose of this study was to investigate in the dog the influence on certain physiologic parameters of transfusion of blood containing platelet: white blood cell: fibrin (PWF) ag... | 123,440 | [
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Investigation of the nature of Australia antigen. I: The absence of biological activity of Australia antigen in human blood leukocyte culture. | Purified and concentrated preparations of Australia antigen had no stimulating effect on leukocytes of human subjects under study when tested either on DNA-polymerase activity, 3H-thymidine uptake or chromosomal alterations. Moreover, in patients with chronic hepatitis and cirrhosis of the liver no correlation between ... | 123,442 | [
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Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.). III. An electron microscopic investigation of the innervation. | In the rabbit pineal gland two types of postganglionic nerve endings were found which are characterized by the presence of small dense-core vesicles or small clear vesicles. Pharmacological and cytochemical experiments showed then to be noradrenergic and cholinergic, respectively. Both types were often present in the s... | 123,484 | [
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Effects of 5,5'-diphenyl-2-thiohydantoin on respiration and oxidative phosphorylation of rat liver mitochondria. | 5,5'-Diphenyl-2-thiohydantoin (DPTH) administered in vitro, inhibited state 3 oxidation, stimulated state 4 oxidation and decreased ADP:O ratio when 3-hydroxybutyrate and succinate were used as substrates. Considerably lower DPTH concentrations were required for the inhibition of 3-hydroxybutyrate oxidation (50% inhibi... | 123,486 | [
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Influence of non-H-2 genotype on the response to H-2-linked mixed lymphocyte reaction stimulating (MLR-S) genes. | The intensity of the mixed lymphocyte reaction to H-2-linked mixed lymphocyte reaction stimulating genes is influenced by non-H-2 genotype. The same H-2 incompatibility results in a stronger mixed lymphocyte reaction when both partners have the C57BL/10ScSnPh genetic background than when they have the genetic backgroun... | 123,514 | [
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Conversion of the arthrodesed hip to a total hip arthroplasty. | Total hip arthroplasty was done in thirty-three patients who had had previous surgical attempts at arthrodesis of the hip. The arthrodesis had failed in nineteen patients, and the other fourteen patients had fused hips with symptoms in the knee and lower back. Thirty-one of the patients had satisfactory functional abil... | 123,532 | [
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Metabolism of peripheral nerve myelin in experimental diabetes. | Previous in vitro studies of the metabolism of the peripheral nerve have been based on incorporation of radioactive precursor into components isolated from whole nerve. In this study we have determined incorporation secifically into myelin components of peripheral nerve by isolating myelin after incubating whole nerves... | 123,535 | [
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The compensation experience of patients with chronic beryllium disease. | The experience of patients with chronic beryllium disease seeking workmen's compensation indicates that the system does not meet its intentions of providing for relief of workers for job-related illness. In the instance of beryllium disease there is undue delay in adjudication of the compensation. This delay has its or... | 123,578 | [
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0.02420667,
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0.009901463,
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-0.252909,
0.04325728,
-0.3750355,
0.0862989,
0.1121545,
0.4729507,
-0.007307... |
Successful separation of Xiphopagus-conjoined twins. | The successful separation of xiphopagus-conjoined twins is described. Such an experience is of course a very gratifying and exciting surgical adventure. | 123,583 | [
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Ethanol metabolism and liver oxidative capacity in cold acclimation. | Exposure of rats to an ambient temperature of 5 degrees C for 4 to 6 weeks led to a 30 to 80 percent increase in the rate of oxygen consumption and a 50 percent increase in the rate of ethanol oxidation by liver slices, a 50 percent increase in mitochondrial alpha-glycerophosphate oxidase activity of liver, and a 100 p... | 123,585 | [
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A family with apparently sex-linked optic atrophy. | A family is described in which a probable new form of sex-linked optic atrophy was found in eight individuals. Some additional neurological abnormalities were noted. Results of studies of the Xg blood group excluded close linkage between the optic atrophy and Xg genes. As a probable coincidence, Huntington's chorea was... | 123,591 | [
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[Hemodynamic compensatory mechanisms of impaired left ventricular contraction in coronary artery disease (author's transl)]. | The effect of chronic coronary insufficiency on the hemodynamics, the geometry and muscle mass of the left ventricle were studied in 30 patients and compared to 13 controls. In these patients the cardiac output was normal in spite of impaired contractility and left ventricular wall movement. The impaired cardiac perfor... | 123,608 | [
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... |
[Leeches in the respiratory system (author's transl)]. | The leech as a foreign body and parasite in the human respiratory tract occurs principally in the Mediterranean countries, in Africa and Asia. It reaches the respiratory tract when water is drunk directly from rivers, lakes, etc. Ignorance of this fact may cause diagnostic difficulties leading to errors in treatment. A... | 123,618 | [
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Laparoscopy: routine pneumoperitoneum via the posterior fornix. | To induce pneumoperitoneum for laparoscopic examination, a transvaginal route and a modified Verres needle were used in an effort to reduce the failure rate of the subumbilical route and to avoid some of its dangers. The technic not only reduces the rate of complications, but its precision and simplicity make it easier... | 123,638 | [
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0.1873358,
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Genetic evidence on the organization and action of the qa-1 gene product: a protein regulating the induction of three enzymes in quinate catabolism in Neurospora crassa. | The first three reactions in the catabolism of qainic acid in Neurospora crassa are under the genetic control of the qa gene cluster. This cluster consists of three structural genes encoding three inducible enzymes plus a regulatory gene (qa-1+) whose diffusible product apparently acts in a positive fashion to initiate... | 123,642 | [
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[The epidemiologic significance of tuberculosis mycobacteria of the avian type]. | Reaction to intradermal injection of tuberculin from Mycobacteria tuberculosis of the avian type proved to be negative in all the 505 students examined who never came in contact with fowl farms. Of 738 local residents it was found to be positive in 23.8% and of 320 workers of fowl farms--in 54.5% of cases. In response ... | 123,686 | [
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Clinical and microbiologic surveillance of neonatal staphylococcal disease. Relationship to hexachlorophene whole-body bathing. | Neonatal staphylococcal disease occurred in the nurseries of a university hospital three weeks after discontinuation of routine, daily, whole-body bathing of newborns with hexachlorophene. Of 16 infants who had clinical manifestations within a two-week period, 11 cases were confirmed bacteriologically. Shortly after on... | 123,704 | [
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0.289926,
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Occurrence of gastrointestinal parasites in Georgia cattle. | A survey of gastrointestinal nematodes in Georgia cattle was conducted from 1968 through 1973 from actual worm counts from viscera of 145 slaughtered beef cattle or from egg counts made from fecal samples from 3,273 beef and 100 dairy cattle. Beef cattle were grouped as calves, yearlings, and cows. Dairy cattle were gr... | 123,711 | [
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0.03383632,
0... |
[Mycosis fungoides]. | The classical characteristics of Myocsis Fungoides are discussed. 1) The clinical characteristics of the three forms: tumour from the start, erythrodermic and polymorphic forms of Alibert-Buzin. 2) Histological characteristics : dense dermal infiltrates or epidermotropic infiltration, or around a more or less malignant... | 123,718 | [
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Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations. | In Neurospora crassa, the phosphate-metabolizing enzymes are made during phosphate starvation, but not under phosphate sufficiency. The synthesis of these enzymes is controlled by three regulatory genes: pcon-nuc-2, preg and nuc-1, pcon-nuc-2 and preg are closely linked. A model of the hierarchical relationships among ... | 123,873 | [
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0.145... |
24-Hour secretory pattern of dehydroisoandrosterone and dehydroisoandrosterone sulfate. | Dehydroisoandrosterone (DHA) and cortisol were measured by radioimmunoassay and protein binding techniques respectively in plasma from blood taken at 20-min intervals over 24-h periods in 3 normal men, 2 women with Stein-Leventhal syndrome and a man with a benign adrenocortical adenoma. In all subjects but the latter, ... | 123,927 | [
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Insulin and glucose as modulators of the amino acid-induced glucagon release in the isolated pancreas of alloxan and streptozotocin diabetic rats. | The hyperglucagonemia that occurs in vivo in animals made diabetic with alloxan or streptozotocin is not suppressed by high glucose but is suppressed by exogenous insulin. These observations together with other studies suggested that insulin-dependent glucose transport and metabolism by the alpha-cells serves as the pr... | 123,928 | [
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... |
The fungicidal mechanisms of human monocytes. I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms. | We tested the ability of human peripheral blood monocytes to kill Candida albicans and Candida parapsilosis. Evidence that multiple fungicidal mechanisms operate in normla monocytes was found. Normal monocytes ingested and killed viable C. albicans, and could iodinate heat-killed C. albicans. Both functions were defect... | 123,929 | [
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0.1665609,
0.1904231... |
Reduction of fear-related dental management problems with use of filmed modeling. | In this study of the modification of anxiety-related disruptive behavior in dental treatment, matched groups of inner-city children attending a pedodontic clinic were shown a videotaped demonstration of a 4-year-old black child undergoing a dental restorative procedure or were given an unrelated drawing task before den... | 123,932 | [
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[Medial or lateral placement of the graft in myringoplasty comparative studies of both operation techniques using electronic data processing (author's transl)]. | After medial placement of the graft in myringoplasty the remaining air-bone gap within the speech range is on an average approximately 10,- dB. This remaining air-bone gap is, according to secured statistics, on an average approximately 10 dB lower than in a lateral placement of the graft. The bone conduction does usua... | 123,984 | [
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Does phospholipase C stimulate thymide kinase activity of rat liver extracts prepared after partial hepatectomy. | Our purpose was to determine whether phospholipase C stimulated thymidine kinase activity of regenerating rat liver. We determined effects of phospholipase C upon TMP formation by rat liver extracts prepared at 0, 12, 24, 36 and 48 hr following partial hepatectomy. Data were obtained which supported these conclusions: ... | 124,059 | [
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... |
Heterotopic bone formation in abdominal scars. | Twelve patients with heterotopic ossification in abdominal scars have been studied. Two patients were elderly females. Operative excision was required in seven: two for local symptoms, two for suspected local malignant recurrences and three for further intra-abdominal procedures. The other five instances were diagnosed... | 124,093 | [
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Echinococcal cyst beyond the pulmonary sieve. | This is a presentation of 10 unusual cases of hydatid cyst beyond the pulmonary sieve. One of these cases has not been described previously. Some comments and a discussion are included. | 124,095 | [
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[Experience with prophylactic examinations of rural women for the detection of malignant neoplasms (based on data from the northern group of districts of the Udmurt ASSR)]. | Difficulties in the organization of adequate prophylactic examinations have necessitated an application of the expedition method of examining the population by a team of specialists. This method has been used in North Regions of Udmurt ASSR, and since 1962 a total of 13425 females were examined, who shoed pathological ... | 124,112 | [
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... |
Proteolytic enzymes as adjuncts to antimicrobial prophylaxis of contaminated wounds. | When a tissue is injured, its vessels exhibit a marked increase in vascular permeability. Blood proteins, including fibrinogen, traverse the vessel walls and lead to the development of a surface coagulum. This inflammatory response continues until primary closure of the wound edges is accomplished. The thickness of the... | 124,138 | [
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0.2277873,
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0.3439296,
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Evaluation of prosthetic grafts of different porosity for arterial reconstruction. | Autogenous jugular veins and Dacron grafts of different porosities were implanted as short bypass grafts around ligated femoral arteries in the dog. Patency rates for periods up to eight months were: vein, 79 per cent; DeBakey Dacron (lowest porosity), 39 per cent; Wesolowski Weavenit (imtermediate porosity), 56 per ce... | 124,139 | [
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0.2564498,
0.0658015,... |
Development and treatment of post-traumatic pulmonary platelet trapping. | In anesthetized dogs soft tissue trauma resulting in hypovolemia was associated with pulmonary trapping of 51Cr tagged platelets. The efficacy of various forms of therapy aimed at preventing pulmonary trapping of platelets following trauma was evaluated. Lung biopsies were assayed before trauma and at hourly intervals ... | 124,157 | [
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The use of Mersilene mesh in repair of abdominal wall hernias: a clinical and experimental study. | Use of synthetic materials in herniplasty has been a controversial issue. In order to determine the influence of Mersilene mesh on the strength of healing abdominal wounds and its effectiveness in repair of hernia, experimental and clinical studies were undertaken. Experimental study included 175 male rats divided into... | 124,162 | [
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... |
Some sources of stress found in mothers of spina bifida children. | The scores on a malaise inventory for 51 mothers of spina bifida children born between 1956 and 1962 in South Wales revealed significantly higher scores when the child was incontinent, had a severe locomotor disability, had an IQ less than 80, and was attending a special school rather than a normal school. No differenc... | 124,188 | [
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0.1444436,
0.02177... |
Adverse reactions to trimethoprim-sulfamethoxazole, with particular reference to long-term therapy. | Since trimethoprim-sulfamethoxazole (TMP-SMX) was first marked occasional reviews have surveyed the pattern of adverse reactions. Skin rashes characteristic of sulfonamide sensitivity have predominated, with relatively few of a serious exfoliative nature. Hematologic adverse reactions recorded follow the pattern known ... | 124,200 | [
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0.3309428,
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0.43109,
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De subitaneis mortibus. XII. Asymmetrical hypertrophy of the heart. | Subjects with asymmetrical hypertrophy of the heart are prone to sudden death. Neither the pathogenesis of the eccentric hypertrophy nor the mechanism of sudden death is fully understood. In this report we describe certain postmortem findings in the hearts of 22 subjects who died suddenly, silently and unexpectedly, an... | 124,234 | [
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0.1059661,
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0.1869512,
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0.2261338,
0.3273998,
-0.4815448,
... |
[Preparative electrophoresis of peptidic glycosaminoglycans. Application to the fractionation of peptidic glycosaminoglycans of arterial wall (author's transl)]. | A new procedure for the fractionation of glycosaminoglycans by electrophoresis on Pevikon has been described. Mixtures of glycosaminoglycans were fractionated by preparative electrophoresis on Pevikon in pyridine formate or glycine-HCl buffers. By this procedure, 200 mg of a mixture of hyaluronic acid, heparan sulphate... | 124,318 | [
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0.283521,
0.4123589,
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-0.0192... |
Is the macrophage the stimulating cell? | Using CAF1 spleen cells to stimulate parental strain BALB/c spleen cells in a mixed lymphocyte culture, column separation of responding cells increased their response whereas the same treatment of stimulating cells reduced their activity approximately 95 per cent. Peritoneal macrophages from CAF1 mice were found to sti... | 124,322 | [
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0.4742424,
0.125804,
0.06173593,
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In vitro cultivation of adult human gingiva I. primary epithelial outgrowth from gingival explants. | The in vitro behavior of human gingiva was studied using a simple tissue culture technique. Gingival explants from adult patients undergoing periodontal surgery were cultivated in three different media for periods up to three weeks. It was demonstrated that primary epithelial cell cultures can be obtained under simpl... | 124,339 | [
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0.2168821,
0.6487071,
0.3345265,
0.009... |
Effect of gentamicin on renal function in the rat. | The functional correlates of gentamicin nephrotoxicity were studied in rats injected with gentamicin, 100 mg/kg b.wt. per day, for 1 to 6 days. After 4 days of injections, a significant decrease in urine osmolality was detected in association with a rise in blood urea nitrogen and serum creatinine. These changes became... | 124,348 | [
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0.122,
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0.1410337,
0.123... |
Coexistent ipsilateral subclavian steal and thoracic outlet compression syndromes. | In this report we shall describe a 34-year old woman who presented with signs and symptoms of ipsilateral subclavian steal and thoracic outlet compression syndromes. The diagnosis was confirmed by arteriography and measurement of nerve conduction velocities. Via a single approach, the first rib was resected, the left s... | 124,372 | [
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0.1223312,
... |
Indications, contraindications and complications of laparoscopy. | The primary use of laparoscopy is as a surgical tool, with sterilizations being the overwhelming indication. The laparoscope is used less frequently as a non-surgical tool, with the major indication being for diagnosing infertility and/or amenorrhea, and for evaluation of obscure pelvic pain. There would seem to be sev... | 124,409 | [
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0.1318781,
0.009553713,
-0.187227... |
The use of viable frozen lymphocytes for studies in human tumor immunology. | Viable frozen lymphocytes displayed activity in blastogenesis assays that was indistinguishable from freshly prepared lymphoid cells. Similarly, cytotoxic activity of lymphocytes against melanoma target cells from melanoma patients was only slightly affected by the freezing procedure. Frozen lymphocytes provided a hig... | 124,484 | [
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0.5395449,
0.4732111,
0.2592566,
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Ultrastructural features of degenerated cardiac muscle cells in patients with cardiac hypertrophy. | Degenerated cardiac muscle cells were present in hypertrophied ventricular muscle obtained at operation from 12 (38%) of 32 patients with asymmetric septal hypertrophy (hypertrophic cardiomyopathy) or aortic valvular disease. Degenerated cells demonstrated a wide variety of ultrastructural alterations. Mildly altered c... | 124,533 | [
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0.3848578,
0.3035576,
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0.04... |
Sebum: analysis by infrared spectroscopy. II. The suppression of fatty acids by systemically administered antibiotics. | Various tetracyclines and erythromycins have been used rather empirically for the systemic treatment of acne vulgaris for more than a decade. It has been impossible to accurately evaluate clinically the numerous derivatives and to compare their effectiveness with other antibiotics such as clindamycin. As a substitute f... | 124,557 | [
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0.4433298,
0.03269569,
... |
Measles rash. I. Light and electron microscopic study of skin eruptions. | Measles skin lesions were studied by light and electron microscopy. In the epidermis multinucleated giant cells were observed just beneath the hypertrophic horney layer at the maximum stage of rash; they were believed to result by an abnormal process of hyper- or parakeratosis. Neither typical inclusions nor viral nucl... | 124,564 | [
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0.544291,
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0.177101,
... |
Zinc distribution in mouse brain subsequent to hippocampal lesions. | The role of zinc in central nervous system metabolism remains obscure but it has been shown in animals that diphenylthiocarbazone (Dithizone) selectively colors intravitally the hippocampus and adnexa, parts affected in human temporal lobe epilepsy. To examine the effect of experimental cerebral lesions on zinc storage... | 124,565 | [
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0.1151082,
0.4066212,
-0.2... |
Acute myocardial infarction in toxic cardiomyopathy without coronary obstruction. | Confluent left ventricular scar without significant coronary obstruction has been found in alcoholic subjects at autopsy. To evaluate the pathogenesis, 12 patients with chronic alcoholism and severe precordial pain persisting 4-24 hours were observed clinically. Cardiac isoenzymes of lactic dehydrogenase rose in serum.... | 124,634 | [
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0.3516937,
0.3741616,
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Molecular size difference of urinary heparan sulfates from normal individuals and genetic mucopolysaccharidoses. | Heparan sulfates were isolated from the urine of normal individuals and patients with genetic mucopolysaccharidoses after exhaustive digestion with chondroitinase ABC. Electrophoresis of these preparations on cellulose acetate membrane revealed one spot corresponding in mobility to reference heparan sulphate in barium ... | 124,636 | [
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0.36632,
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0.1610157,
-0.0006702887,
0.0830956... |
Low back pain with femoral neuritis. | In 465 patients treated surgically for low back and lower extremity disability, almost 10 per cent had femoral rather than sciatic distribution of pain. The average age of patients who had a primarily femoral distribution of pain is higher by a decade than those who had a predominantly sciatic distribution of pain; the... | 124,641 | [
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0.01090241,
0.2745009,
0.4112104,
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[Anastomoses between the vertebral and external occipital arteries in occlusion of the external carotid and vertebral arteries (author's transl)]. | Five cases of anastomose formation between the external carotid and the vertebral arteries are reported. In 2 cases occlusion of the vertebral artery in the upper section of the cervical spine were present. In 2 further cases there were occlusions of the external carotid artery. In only a single case did angiographic e... | 124,679 | [
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0.1756465,
0.05537374,
... |
Histochemical mapping of ATPase and simple esterase in the cerebral hemisphere of the Indian lizard, Uromastix hardwickii. | Adenosine triphosphatase (ATPase) and simple esterase (SE) have been mapped at various levels of the cerebral hemispheres of the lizard, Uromastix. Some areas were intensely positive for one or both enzymes while others were totally negative for both. Variation in enzymatic activity has been observed at different level... | 124,718 | [
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0.234327,
0.1046928,
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... |
Isolation and properties of actin, myosin, and a new actinbinding protein in rabbit alveolar macrophages. | Actin, myosin, and a high molecular weight actin-binding protein were extracted from rabbit alveolar macrophages with low ionic strength sucrose solutions containing ATP, EDTA, and dithiothreitol, pH 7.0. Addition of KCl, 75 to 100 mM, to sucrose extracts of macrophages stirred at 25 degrees caused actin to polymerize ... | 124,734 | [
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0.0551927,
0.1650154,
0.2186172,
0.01578771,
-0.028970... |
Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages. | D+ but not D- myeloid leukemic cells can be induced by the appropriate conditioned medium or by serum from endotoxin treated mice, to undergo cell migration in agar, cell attachment to the surface of a Petri dish and differentiation to mature macrophages and granulocytes. Inhibition of cell multiplication by cytosine a... | 124,742 | [
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0.5565512,
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0.00790163,
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0.07381593,
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0.4347042,
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0.3639488,
0.5256574,
-0.08366238,
-0.237541... |
Mixed lymphocyte culture determinants and C2 deficiency: LD-7a associated with C2 deficiency in four families. | Four families with C2 deficiency were studied. Among eight HL-A haplotypes involved with C2 deficiency, five were HL-A 10,W18. Three homozygotes for C2 deficiency from different families were mutually nonreactive in mixed lymphocyte cultures (MLC) and the heterozygotes from the fourth family failed to react to the ho... | 124,762 | [
-0.05806448,
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0.1791141,
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0.3181492,
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0.08661056,
0.3380598,
0.2425822,
0.086703... |
[Depression of contractile function and decrease of the effectiveness of oxygen utilization during compensatory heart hypertrophy]. | Heart hypertrophy was produced in rats by creating a coarctation of the aorta 4 months prior to the experiment. The conducted study of the contractile function and oxygen consumption in isolated working hearts demonstrated a marked decrease in the contractile function of the hypertrophied hearts, as compared to the int... | 124,793 | [
-0.2531005,
0.1024592,
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0.02116587,
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0.1124708,
0.5278147,
0.2476429,
0.1108463... |
[Blindness according to the law in Schwerbeschädigten-Gesetz, Schwerbehinderten-Gesetz, Bundessozialhilfe-Gesetz and Bundesversorgungs-Gesetz (author's transl)]. | It is possible to calculate the granulation of disturbances of vision in combined disturbances (reduction of central vision and visual fields defects) with the aid of the tables in the "Anhaltspunkte für die ärztliche Gutachtertätigkeit im Versorgungswesen". The total disability with 160% is equal to the disturbance of... | 124,797 | [
-0.1760612,
0.2270193,
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0.06291337,
0.5800821,
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0.07670255,
0.2623487,
0.2410383,
-0.01015423,
... |
[Discrepant findings between esophagoscopical and x-ray examination on the search for varicose veins of the esophagus (author's transl)]. | In a comparising study of 191 liver-patients, who were laparoscopical and most of them histological examined, the results of registrated varicose veins of the esophagus by x-ray and fiber-esophagoscopical examination were compared. Between x-ray and esophagoscopical examination in our material was a discrepancy in 29,3... | 124,812 | [
0.1353159,
-0.002865317,
-0.3728797,
-0.1560226,
0.2591432,
-0.1239714,
-0.3478499,
-0.3060834,
0.03901144,
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0.2241741,
0.1458656,
0.1732076,
0.03039559,
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0.3690648,
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0.2704184,
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0.300445,
0.1997119,
0.1365004,
-0.3215243,
0.0... |
[Glycolic acid/polymer as suture material]. | Tissue reactions to polyglycol acid and plain catgut threads were compared. The second part of the paper deals with changes in the mechanical properties of the polymer. Their reduction after insertion in tissues was proportionally equal for threads of different sizes. This finding is explicable histologically, since it... | 124,829 | [
0.155095,
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0.058399,
0.2659359,
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0.295887,
0.1675284,
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0.252756,
-0.2214561,
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0.2604172,
0.02812123,
0.357101,
0.4330669,
-0.04660129,
-0.2227581,
-0.13209... |
Failures of laparoscopy sterilization. | Female sterilization by laparoscopy has become widely accepted throughout the United States and Europe. The failure rate of this procedure is still speculative. In the course of 4200 operative sterilization, 32 failures have been identified and 31 of these have been subsequently evaluated. The most common finding was... | 124,835 | [
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0.08850302,
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0.197286,
0.2347162,
-0.05847221,
0.4... |
[Comparative evaluation of several methods of identifying leishmania]. | A parallel study of 25 strains of Flagellata isolated from 6 species of sand flies was carried out by means of biotest, Adler's serological method modified by Safjanova and "temperature" method. It was established that the use of several methods for the identification of Leishmania allows more reliable results to be ob... | 124,844 | [
0.2388926,
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0.02154245,
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0.05065178,
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0.3089218,
0.1179936,
-0.1214972,
0.03038698... |
[Possible causes determining the developmental rhythm of populations of the nasopharyngeal gadfly of sheep, Oestrus ovis L. (Diptera, Oestridae)]. | On the basis of observations undertaken in Azerbaijan and available literary data the author considers the hypotheses concerning the reasons causing the delay of the Ist instar larvae development and determining the age structure changes in population of Oestrus ovis L. within a year. The main reasons are as follows: f... | 124,845 | [
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0.141845,
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0.3545923,
0.5403459,
-0.1979584,
... |
Effect of glucose on the utilization of palmitate 1 14C by rat kidney cortex slices. | The authors studied the effect of glucose on the uptake and utilization of palmitate 1 14C by rat kidney cortex slices. They found that its inhibitory effect on free fatty acid (FFA) uptake was caused by inhibition of the incorporation of 1 14C-labelled palmitate into the total lipids and FFA and by reduced oxidation t... | 124,890 | [
0.1162986,
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0.2702894,
0.06751318,
0.3748923,
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... |
One-stage reconstruction for exstrophy of the bladder in girls. | In an African female infant with exstrophy who was a candidate for complete reconstruction of the urinary tract, pelvis, and abdominal wall, the treatment program was simplified by performing iliac osteotomies at the same time as the other repairs, using a single transverse lumbosacral incision for access. A series of ... | 124,897 | [
-0.1121843,
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-0.09653912,
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0.006131044,
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-0.6631737,
-0.6513519,
0.1986548,
0.2497878,
0.2531981,
-0.2716629,
-0.2614144,
0.005449497,
-0.5260231,
-0.2384874,
-0.4879344,
-0.3045681,
-0.3426537,
-0.5323606,
0.2016087,
0.04197552,
-0.17056... |
HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes. | When human lymphocytes are cultured for 9 to 14 days with stimulating cells of a family member differing by a single HL-A haplotype they become "primed" to recognize specific HL-A LD (mixed lymphocyte culture) antigens. These primed lymphocytes respond specifically and rapidly when "restimulated" with cells of a person... | 124,948 | [
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0.04442536,
0.09724305,
0.4592136,
0.08023294,
-0.05891324,... |
Adenosine diphosphate effect on contractility of human muscle actomyosin: inhibition by ethanol and acetaldehyde. | Magnesium adenosine triphosphate (Mg-2+-ATP) is known to produce dissociation of muscle actin and myosin in vitro, while its hydrolysis leads to reassociation. The interaction of purified actin and myosin from human muscle, in the presence of Mg-2+-ATP, was stimulated by minute amounts of adenosine diphosphate (ADP), a... | 124,949 | [
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0.2967975,
0.530731,
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-0.1895681,
0.2... |
A case of Marfan's syndrome with absent right coronary artery complicated by aortic dissection and right ventricular infarction. | The first patient to be reported with Marfan's syndrome and an absent right coronary artery is described. Dissection of the ascending aorta was associated with right ventricular infarction which was probably due to the coronary artery anomaly and caused his death. | 124,959 | [
-0.3479291,
0.01095617,
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0.1663639,
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0.4455071,
0.1593328,
-0.0778814,... |
[Light- and electronmicroscopic findings in nine auto-alloplastic vascular grafts (Sparks-Mandril) (author's transl)]. | Auto-alloplastic arterial prostheses with a dacron mesh of 1 or 2 layers according to Sparks were investigated by light and electron microscopy after variable times of incorporation and perfusion. At the end of the organization-period the characteristic structure of the wall is composed of three layers. The interior la... | 124,963 | [
0.1455013,
0.1798498,
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0.09947676,
0.111057,
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0.2992343,
0.7559989,
0.03433613,
0.04098282,
0.40... |
The in vivo inhibition of tumor growth by ruthenium red: its relationship with the metabolism of calcium in the tumor. | Ruthenium red shows antitumor activity on experimental tumors. This growth inhibition seems to be related with the impairment of Ca-2+ transport both at the mitochondrial and at the cell membrane level. A sex influence modifying this inhibition and the systemic effects has been observed. | 125,011 | [
-0.2307442,
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0.03031135,
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0.2144112,
0.05826452,
0.0142374,
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-0.08625936,
0.09216127,
0.2196213,
0.07618075,
-0.238312... |
A fluid-filled intrauterine device: initial clinical trials. | Initial clinical trials of a saline-filled IUD were conducted with 697 women (397 nulliparas and 307 multiparas) experiencing 6,672 woman-months of use. The cumulative rates for multiparas were: pregnancy 1.5, expulsion 10.5, medical removal 10.9, continuation 68. For nulliparous women the rates were: pregnancy 4.3, ex... | 125,043 | [
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0.3767968,
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0.4092574,
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0.09464425,
0.07852578,
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0.08814973,
0.01733351,
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0.08785717,
0.08683525,
-0.2448925,
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0.09744273,
0.1201807,
0.068712... |
Controlled test of anthelmintic activity of levamisole administered to calves via drinking water, subcutaneous injection, or alfalfa pellet premix. | A controlled test of the activity of 3 formulations of levamisole, at the dose level of approximately 8 mg/kg, against naturally occurring infections of gastrointestinal parasites and lungworms was made in 24 calves allotted to 4 groups of 6 calves each. Levamisole was administered to group I calves in the drinking wat... | 125,055 | [
-0.3321299,
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0.07339333,
0.1180005,
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0.2550789,
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0.05686883,
-0.04248292,
0.05005862,
0.08240566,
0.2577165,
0.... |
Size of adipose cells in infancy. | Seventy-three samples of adipose tissue from 59 infants, aged from 25 weeks' gestation to 18 months of age, were obtained at necropsy, or at operations, or by needle biopsy. Adipose cell size was measured by microscopy. During fetal life the mean cell diameter increases from about 40 mum at 25 weeks' gestation to 50-80... | 125,072 | [
0.05534992,
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0.0002928623,
0.1398752,
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0.2967306,
0.0439331,
0.1358699,
0.4477953,
0.1667765,
-0.00806053... |
[Family studies for detection of latent psoriatics by assay of alterations in steroid metabolism (author's transl)]. | In psoriasis changes of the DHEA metabolism could be demonstrated. These genetically determined basic alterations may represent an important factor for the manifestation of psoriasis. They consist of a decreased penetration of DHEA through the cell membrane and an increased reduction of DHEA to ADIOL, leading to a redu... | 125,074 | [
0.1975984,
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0.1922213,
0.03242573,
0.5433089,
0.8563615,
0.1106944,
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0.... |
The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus. | A series of in vivo and in vitro investigations was performed to examine the localisation of sorbitol pathway activity in the rat renal cortex and to investigate the possible relation that the acculumation of sorbitol pathway intermediates in renal cortical tissue may have to the pathogenesis of renal complications in ... | 125,079 | [
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0.02427142,
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0.01372939,
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0.2292636,
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0.02871621,
-0.09355001,
0.1306375,
0.2576595,
0.04958589,
0.2299911,
0.5786914,
-0.03616721,
... |
Relationship between intracellular K+ concentrations and K+ fluxes in growing and contact-inhibited cells. | The K+ content and the K+ flux were measured in the cell lines ME2 and MF2 isolated from plasmocytoma MOPC 173. Both cell lines were shown to have the seem K+ content and the same K+ steady state flux per unit of surface area. In ME2 cells, no modification of the exchange movement was observed during contact inhibition... | 125,110 | [
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0.2106382,
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0.3168955,
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0.2867782,
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-0.1578379,
-0.2184896,
0.3501303,
0.7162965,
-0.1979036,
-0.1048... |
[Symbiotic efficiency in spontaneous mutants of Rhizobium legumino-sarum resistant to streptomyocin, spectinomycin, or kanamycin]. | Symbiotic effectiveness of 45 mutant strains selected from four wild effective strains of Rhizobium leguminosarum for resistance to streptomycin, spectinomycin or kanamycin was determined on Vicia faba. Loss of effectiveness occurred in twenty of these mutants; distribution of ineffective mutants was uniform among the... | 125,155 | [
0.1319031,
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0.1292393,
0.2276134,
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0.02840776,
0.1891776,
0.05310953,
0.09952555,
0.1493904,
0.02809713,
... |
Electrophysiologic and pathologic correlations in two cases of chronic second degree atrioventricular block with left bundle branch block. | This study concerns two cases of chronic 2 degrees atrioventricular (A-V) block with left bundle branch block (LBBB). Pathological studies included serial section of the conduction systems. Case 1 had type I 2 degrees block with LBBB. Electrophysiological studies revealed type I 2 degrees block proximal to the His bund... | 125,157 | [
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-0.5097897,
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0.1404976,
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0.04340795,
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0.1262071,
0.08885604,
0.4246193,
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0.009277209,
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0.1751557,
0.3253068,
-0.2126692,
0.1407597,
0.241913,
-0.2272364,
... |
Effect of duration of insulin deficiency on membrane-bound and free ribosomes from livers of diabetic rats. | In order to define the effect of duration of diabetes on hepatic protein sysntesis, membrane-bound and free ribosomes were isolated from livers of rats, 3, 7 and 28 days after administration of intravenous streptozotocin (75 mg/kg). Hepatocytes from the same rats were subjected to ultrastructural quantitative analysis.... | 125,211 | [
0.1117216,
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0.5167962,
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0.233714,
0.2622845,
0.206112,
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0.3502545,
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0.1967622,
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0.06319828,
0.09072424,
-0.2617871,
0.4460457,
0.2273178,
0.1857281,
-0.2... |
Influence of mixtures of taurocholate, fatty acids, and monolein on the toxic effects of deoxycholate in rat jejunum in vivo. | The influence of mixtures of taurocholate (TC), oleic acid (OA), caprylic acid (CA), and monolein (MO) on the toxic effects of deoxycholate (DC) in rat jejunum have been investigated using both a closed loop and perfusion technique. DC induced net secretion of water and electrolytes, inhibited glucose transport and tra... | 125,213 | [
-0.0220327,
-0.1678405,
-0.1140849,
0.01864015,
0.2036625,
-0.288196,
0.02859378,
0.2164464,
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0.1255127,
0.03856118,
0.04238255,
0.2607548,
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0.05740259,
0.2088628,
0.2122424,
-0.1053902,
-0.09648902,
0... |
Sex chromatin and cytogenetic survey of 10417 adult males and 357 children institutionalized in Belgian institutions for mentally retarded patients. | A survey of adult male immates of the major institutions for mental patients in Belgium was undertaken in 1965. Out of 10417 males examined 61 had positive sex chromatin (5.8%); 201 had bilateral small testis (1.9%), 4 hypogonad patients carried a D/D translocation. Out of 857 karyotyped children, 2.9% carried an autos... | 125,226 | [
-0.07889162,
0.3905191,
0.4681715,
0.0575284,
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0.1059926,
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0.2237503,
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0.3054637,
0.001781717,
0.05064967,
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-0.5791597,
-0.03833254,
0.08728717,
-0.3204067,
0.3145629,
0.03931036,
-0.2956218... |
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