title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Automated method for the determination of niacin and niacinamide in cereal products: collaborative study. | In a collaborative study, an automated method for the determination of niacin and niacinamide in cereal products was compared with the official final action microbiological (43.121-43.125) and chemical (43.044-43.046) methods. Ten samples of cereal products, including enriched flour, yeast-leavened baked products, fort... | 125,257 | [
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Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma. | Proteoglycan monomer (D1) and aggregate (A1) preparations were isolated from 4 M guanidinium chloride extracts of the Swarm rat chondrosarcoma. When EDTA, 6-aminohexanoic acid, and benzamidine were present in the solutions, the D1 preparation contained a single component (SO = 23 S), and the A1 preparation contained 30... | 125,282 | [
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The substructure of heavy meromyosin. The effect of Ca2+ and Mg2+ on the tryptic fragmentation of heavy meromyosin. | Heavy meromyosin, obtained by tryptic digestion of myosin, containing two main polypeptides whose masses were estimated as 81,000 and 74,000 dlatons from Na dodecyl-SO4 polyacrylamide gel electrophoresis, was further digested with trypsin. The Ca2+-activated ATPase activity remainded unchanged and the K+-EDTA activity ... | 125,283 | [
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Immune complexes in sera and synovial fluids of patients with rheumatoid arthritis. Radioimmunoassay with monocylonal rheumatoid factor. | Evidence for the presence of immune complexes in blood, synovial fluid, and tisues of patients with rheumatoid arthritis (RA) includes low complement levels in blood and effusions, deposition of immunoreactants in tissues and vessel walls, precipitate formation after addition of monoclonal rheumatoid factor (mRF) to se... | 125,289 | [
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Studies on the mechanism of inhibition of the red cell metabolism by cardiac glycosides. | The purpose of this work was to test the previously suggested hypothesis that the inhibitory effect of ouabain on lactate production in human red cells is due to an interaction between phosphoglycerate kinase and (Na+ + k+)-activated adenosine triphosphatase (Na+,K+ATPase). An antibody to red cell phosphoglycerate king... | 125,326 | [
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Echocardiographic classification of hypertensive heart disease. A correlative study with clinical features. | Forty patients with systemic hypertension were classified into 4 types based on the left ventricular echocardiographic findings. Patients with normal left ventricular echogram, type I, showed little clinical symptoms and signs of hypertensive involvement. Higher systolic pressure and marked hypertensive retinal and ren... | 125,353 | [
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The effect of continued cigarette smoking on the patency of synthetic vascular grafts in Leriche syndrome. | The effects of continued smoking were studied in 187 consecutive patients who underwent aorto-iliac or aorto-femoral grafting because of Leriche disease and who left the hospital with well-functioning grafts. The patients were divided into the following groups: (1) never smoked, (2) stopped smoking after the operation,... | 125,365 | [
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Female sterilization. II. A comparison of methods. | An analysis was made of 1757 female sterilization procedures performed over a 5 1/2-year period. The majority of these were accomplished by one of 8 technics: puerperal abdominal tubal ligation (TL), cesarean section plus TL, hysterotomy plus TL, interval abdominal TL, colpotomy TL, laparoscopic TL, vaginal hysterectom... | 125,399 | [
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Composite materials for dental implants. | The requirements of endosteal dental implants are unique and stringent. The materials currently applied to implantation do not offer convincing evidence of satisfying these needs. This preliminary study reports on attempts at developing materials which would aid in obtaining a mucosal seal to maintain the integrity of ... | 125,400 | [
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Changes in pancreatic tryptophan in the rat in response to fasting. The effect of B-cytotoxic agents and variation through the oestrous cycle. | The concentration of tryptophan not incorporated into protein or polypeptides in the pancreas of male rats rose two- to three-fold in response to a 24 hrs period of food deprivation. On refeeding or intra-peritoneal administration of glucose the level of tryptophan in the pancreas fell, while that in the serum rose. Th... | 125,406 | [
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[Mannonidosis. Apropos of 5 cases]. | Mannosidosis remains an extremely rare entity (9 published cases). Our personal experience, based upon 5 cases, suggests that the diagnosis may be based upon both positive as well as negative clinical and paraclinical data, which differentiate the disorder from other diseases which it resembles. The use of simple metho... | 125,411 | [
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The assessment of histocompatibility by mixed lymphocyte reaction as measured by the macrophage electrophoretic mobility (MEM) test. | The mixed lymphocyte reaction (MLR) between donor and recipient lymphocytes has been measured by the macrophage electrophoretic mobility (MEM) test and the modified (MOD-MEM) test. Its value as a measure of compatibility has been assessed by comparison with conventional HL-A serotyping and with the outcome of renal tra... | 125,469 | [
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Cerebral atherosclerosis and its relationship to selected diseases in Nigerians: a pathological study. | Factors which are known to be associated with cerebral atherosclerosis were evaluated in Nigerian Africans. Of 465 autopsied adult Nigerians, 62 (13%) had cerebral atherosclerosis. The frequency and severity of atherosclerosis among Nigerians with hypertension, particularly male subjects, were higher than in normotensi... | 125,475 | [
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[Sodium reabsorption and the membrane systems of vertebrate kidneys]. | Sodium reabsorption is low in coldblooded animals (the lamprey Lampetra fluviatilis, red salmon Oncorhynchus nerka, carp Cyprinus carpio, frog Rana temporaria, tortoise Agryonemis horsfieldi) being much higher in warmblooded ones (chicken, pigeon, rat). High level of Na transport in warmblooded animals is paralleled by... | 125,513 | [
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Fractionation of proteoglycans from bovine corneal stroma. | Proteoglycans were extracted from bovine corneal stroma with 4M-guanidinum chloride, purified by DEAE-dellulose chromatography (Antonopoulos et al., 1974) and fractionated by precipitation with ethanol into three fractions of approximately equal weight. One of these fractions consisted of a proteoglycan that contained ... | 125,581 | [
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Stimulation of glycosaminoglycan biosynthesis by amyloid fibrils. | Since amyloid-laden organs have an increased glycosaminoglycan content, the effect of amyloid fibrils on glycosaminoglycan metabolism by normal fibroblasts was examined. In comparison with controls, synthesis of glycosaminoglycans, primarily hyaluronic acid, was increased by an average of 48 and 93% respectively when 0... | 125,588 | [
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Seborrhoeic keratoses and carcinoma of the large bowel. Three cases exhibiting the sign of Lester-trélat. | Three patients who rapidly developed multiple seborrhoeic keratoses and were found to have adenocarcinoma of the large bowel are described. In two cases the discovery of the neoplasm was prompted by skin manifestations. | 125,606 | [
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Complementarity in the regulation of phosphoglucomutase, phosphofructokinase and hexokinase; the role of glucose 1,6-bisphosphate. | ATP and citrate, the well known inhibitors of phosphofructokinase (ATP: D-fructose 6-phosphate 1-phosphotransferase, EC 2.7.1.11), were found to inhibit the activities of the multiple forms of phosphoglucomutase (alpha-D-glucose 1,6-bisphosphate: alpha-D-glucose 1-phosphate phosphotransferase, EC 2.7.5.1) from rat musc... | 125,609 | [
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Improved purification and partial characterization of (Na+, K+)-ATPase from cardiac muscle. | A method is described for purification of (Na+, K+)-ATPase which yielded approximately 60 mg of enzyme from 800 g of cardiac muscle with specific activities ranging from 340 to 400 mumol inorganic phosphate/mg protein per h (units/mg). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated the presence of ... | 125,612 | [
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Spectinomycin in gonorrhoea. | Of 104 male and nine female patients with uncomplicated acute gonorrhoea who were treated with spectinomycin (males 2 g., females 4 g.), two patients (one male and one female) were considered to be treatment failures. No conclusions can be drawn from the small numbers of female patients investigated. Of the 104 male pa... | 125,619 | [
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[Unusual clinical forms of pseudo-LE syndrome: an induced immune-complex disease? (author's transl)]. | Two of nine patients with pseudo-LE syndrome had previously undescribed organ manifestations. In one there was the full-blown picture of cutaneous lupus erythematodes, with renal and CNS involvement, ending fatally. Immunohistologically there was severe vasculitis and nephritis, histologically generalised necrotizing a... | 125,641 | [
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The treatment of horses with chronic back pain by resecting the summits of the impinging dorsal spinous processes. | This paper describes the surgical treatment of 14 horses exhibiting chronic back pain attributed to impaction and overriding of the dorsal spines in the thoracolumbar region. The technique involved the resection of the summits of one or more dorsal spines following midline division of the supraspinous ligament. All the... | 125,651 | [
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[Xero-radiography of the thorax(author's transl)]. | In over 150 patients, comparative chest examinations were carried out using films and xerography. The following results were obtained: Using xerography, image quality depends significantly on the size and shape of the imaging structure and on its marginal sharpness. Using a sectional technique and xerography, pulmona... | 125,685 | [
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ATPase activity in flagella from Euglena gracilis. Localization of the enzyme and effects of detergents. | The biochemical effects of some detergents on the ATPase activity of isolated flagella from Euglena gracilis are related to morphologic obliterations induced by those detergents. Enzymic activity can be localized by electron microscopy along the microtubules and also on the paraflagellar rod. The nonionic detergent d... | 125,790 | [
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Production of ring-shaped particles by normal and metaplastic tissue. I. Human skin. | Maintenance media incubated with biopsy specimens of human skin tissues contained minute (10-12 nm wide), ring-shaped particles (RSP) similar to those described previously in culture media of mammalian cell lines. In addition to the qualitative demonstration of the particles by electron microscopy, a quantitative metho... | 125,799 | [
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[The problem of tracheal stenosis following laryngectomy (author's transl)]. | The striking frequency of tracheal stenoses following laryngectomy gave reason for considerations on the typical causes. In our case-materials 9 tracheal stenoses were observed following 229 laryngectomies during the period from 1952 to 1972. Two of these cases represent typical stenoses produced by pressure. Within a ... | 125,823 | [
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[The prognosis of the noise-induced permanent hearing-loss (author's transl)]. | Basing on a microscopic study the question was explored whether a TTS is found in the high-frequency range after exposure to a low-frequency tone or not. Such a depression is demonstrable after several registrations with automatic audiometry. This depression is significantly higher in the average of normal-hearing pers... | 125,828 | [
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Thalamocortical relations in the brain of the frog, Their role in the genesis of epileptic electrographic phenomena. | The existence of a thalamocortical reverberating circuit between the dorsal thalamic and primordial hippocampal structures could be proved in the brain of the frog (Rana temporarial) by evoking recruiting potentials. Unlike the turtle, this circuit does not take part in the genesis of electrographic phenomena in the co... | 125,882 | [
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0.02793798,
0.1580201,
-0.06086623,
0.2521679,
0.1150332,
0.03582... |
Effect of hyperbarism on collagenous protein metabolism in granulation tissue. | Rats with subcutaneously implanted polyurethane sponges were exposed 6 hours daily for 7 days to high ambient atmospheric pressures (1.5, 2, 2.5 and 3 ATA). Another group was exposed 4 hours daily for 4 weeks to 3 ATA before inducing granulation tissue formation. 14C-proline was administered 16 hours before terminating... | 125,887 | [
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Ultrastructure of ovarian teratomas in LT mice. | Stem cells of these tumors formed nests consisting of undifferentiated embryonic cells in the center with more differentiated cells towards the periphery. A type viral particles were seen in the cisternae of rough endoplasmic reticulum. Ultrastructurally the stem cells of ovarian teratomas did not differ from stem cell... | 125,956 | [
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Structure-response relationships in noctuid sex pheromone reception. An introductory report. | Electroantennogram (EAG) data reflecting response spectra of male pheromone receptors have been analyzed for 16 species of Noctuidae (Lepidoptera). The test compounds included 100 pheromone analogues, altered in chain length, in position and configuration of double bond(s), and in the functional end groups. On comparis... | 125,976 | [
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[Contribution to the subacute necrotic myelitis (Foix-Alajouanine) (author's transl)]. | A case of a 54 years old man with an acute lumbalgia in result of heavy labour is described. With in 7 years he developed a progressive paralysis of the upper and lower motor neuron type and an insensibility of the inferior extremities. The protein content of the cerebrospinal fluid was increased. The cells were ins... | 125,994 | [
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0.3132361,
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0.2641241,
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Host resistance in sepsis and trauma. | Host resistance to infection was measured by the in vivo response to 5 delayed hypersensitivity antigens and to sensitivity and challenge by dinitrochlorobenzene (DNCB) in 55 seriously ill or injured patients and in 50 preoperative patients. A close correlation between infections, septicemia, death related to infection... | 126,046 | [
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0.5140086,
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Pharmacologic effects of apomorphine in rats with altered level of brain serotonin. | The influence of inhibitors and precursors of serotonin synthesis on motor stimulation, hypothermia and apomorphine-induced stereotypy was studied. The results are discussed with reference to the previously expressed suggestion of a modulating role of serotonin on the mechanism of apomorphine-induced motility and in ap... | 126,051 | [
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... |
Alzheimer degeneration in Down syndrome. Electrophysiologic alterations and histopathologic findings. | Progressive electroencephalographic disorganization and decreased voltage amplitude in the late components of the averaged visual evoked potentials were recorded in the last two years of life of a patient with Down disease and Alzheimer degeneration. Taken together with quantitative histopathologic findings, the electr... | 126,052 | [
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0.12478... |
Clinical trial of glibornuride in diabetes. | Glibornuride is an addition to the second-generation sulphonylureas, that has been shown in clinical trials to be effective and non-toxic. Twenty-three diabetics who were poorly controlled on other oral hypoglycaemic agents and seven newly diagnosed diabetics were treated with glibornuride. The efficacy and lack of tox... | 126,099 | [
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0.3201201,
... |
Lepromatous leprosy presenting with polyarthritis, myositis, and immune-complex glomerulonephritis. | A Pakistani man aged 19 years was admitted to a rheumatological unit in the United Kingdom with acute widespread polyarthritis accompanied by night sweats and fever. Preliminary examination suggested Reiter's disease, but further investigation showed acute glomerulonephritis with uraemia. The possibility of periarterit... | 126,102 | [
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0.04712222,
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Age related changes in the synthesis of connective tissues in the rabbit. | The synthesis of collagen and non-collagen proteins was studied in rapidly growing male New Zealand rabbits. Animals were divided into sexually immature (i.e. 4 and 8 week old) and mature (i.e. 15 and 26 week old) groups. Comparisons of aorta, lung, and liver protein synthesis and accumulation were made to determine th... | 126,136 | [
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0.176569,
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... |
Depressed duodenal calcium absorption in the diabetic rat: restoration by Solanum malacoxylon. | Duodenal calcium absorption is depressed in alloxan and streptozotocin diabetic rats taking normal amounts to dietary vitamin D. Depression of absorption appears to be at least in part the result of altered metabolism of vitamin D with failure to form 1,25-dihydroxycholecalciferol (1,25-(OH)2D3), the vitamin D metaboli... | 126,146 | [
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... |
Regulation of muscle contraction: bindings of troponin and its components to actin and tropomyosin. | The bindings of troponin components to actin and tropomyosin has been studied by cosedimentation with actin and affinity chromatography. It is shown that troponin binds to actin and tropomyosin in the presence and absence of calcium but the binding to actin is sensitive to ionic strength. Troponin-I + C binds to actin-... | 126,151 | [
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0.3535676,
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... |
Morphogenesis of the membrane-bound electron-transport system in sporulating Bacillus megaterium KM. | The properties of electron transport systems present in soluble and particulate fractions of spores of Bacillus megaterium KM?HAVE BEEN COMPARED WIth those of similar fractions prepared from exponential-phase vegetative cells of this organism. The timing and localization of modifications of the electron transport syste... | 126,154 | [
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0.4000632,
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Experimental results to immunomesenchymal suppression. | Wet weight of cotton-pellet granuloma and 35SO4-uptake in the acid mucopolysaccharides (AMPS) of granulation tissue of rats and the number of plaque forming cells (PFC) of mice were investigated after the treatment with antilymphocyte globulin, prednisolone, cyclophosphamide and azathioprine. In this way, the effect of... | 126,213 | [
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0.324799,
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... |
[Systemic changes in occupational vitiligo]. | In three patients with occupational vitiligo caused by paratertiary butylphenol--the first cases observed in the BRD--a functional disorder of the liver was found. In two of these patients splenomegaly was seen. The laboratory findings, the laparoscopic examination and the result of the liver-biopsy are described. It i... | 126,216 | [
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0.4589577,
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Mu-induced polarity in the Escherichia coli K-12 ent gene cluster: evidence for a gene (entG) involved in the biosynthesis of enterochelin. | A strain of Escherichia coli K-12 has been isolated that carries a Mu bacteriophage-induced mutation in the ent gene cluster. Nutritional tests together with examination of the compounds accumulated by the mutant strain indicated that the mutant was blocked both in the synthesis of 2,3-dihydroxy-benzoate and its subseq... | 126,224 | [
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0.1628774,
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Purine base transport in Neurospora crassa. | Observations presented in this paper point to the presence of dual transport mechanisms for the base adenine in Neurospora crassa. Competition for transport, as well as growth inhibition studies using an ad-1 auxotroph, show that the purine bases adenine, guanine, and hypoxanthine share at least one transport mechanism... | 126,225 | [
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0.3310756,
0.2254014,
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[Comparative study of 4 types of polyester arterial prostheses]. | The authors report a comparative study of 4 types of arterial prosthesis made of polyester. After implantation in the dog, the superiority of unfolded Rhodergon velvet prostheses was shown. They have excellent qualities for tissue reconstruction owing to presence of histological structures characteristic of large calib... | 126,247 | [
-0.05603374,
0.07786105,
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0.07746182,
0.09141155,
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Simple amidase test for identification of mycobacteria. | A modified amidase test for differentiation of mycobacteria is described. A total of 224 atypical mycobacteria, 154 Mycobacterium tuberculosis, and 26 M. bovis strains were classified by this procedure. Of the 404 strains of various species studied, 400 exhibited an amidase spectrum identical to the established pattern... | 126,248 | [
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0.03766299,
0.09427218,
... |
Measles infection of human mononuclear cells. I. Acute infection of peripheral blood lymphocytes and monocytes. | A study of the susceptibility of human peripheral blood mononuclear cells to measles virus infection and replication is reported. Resting lymphocytes obtained from adults showed very low levels of infection and virus replication while lymphocytes activated by plant mitogens or allogenic lymphocytes supported mononuclea... | 126,271 | [
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0.1673197,
0.2166707,
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[Dyskinetic lesions of the left ventricle wall. Electrocardiographic data]. | The study of the electrocardiogram in 87 cases of dyskinetic lesions of the left ventricule, including ventricular aneurysms and plaques of post-infarction dyskinesia, all of which underwent surgery, showed a correlation between the size of the dyskinetic lesion and the number of ST elevations in the electrocardiogram ... | 126,414 | [
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... |
[Treatment of hemophilia by self-infusion: clinical and psychological approach (author's transl)]. | Twenty-seven hemophiliacs between the ages of 12 and 17 volunteered in a self-infusion training program. An attempt was made to define a teaching method. It consisted of teaching them about the disease so as they would be able to recognise the site of their bleeding and the limitations of self-treatment. They also acqu... | 126,421 | [
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0.439307,
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... |
[Effects of various adsorbants on coagulation factors (author's transl)]. | Adsorption of clotting factors by various adsorbants is studied (tricalcium phosphate, baryum sulfate or carbonate or citrate, calcium oxalate, aluminium hydroxyde and several silicate such as: kaolin, celite, bentonite, attapulgite, beidellite, asbestos). The main properties of each adsorbant are listed as well as sev... | 126,430 | [
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0... |
Role of B cells in the expression of the PPD response of human lymphocytes in vitro. | Human blood lymphocytes were tested for their proliferative response to purified protein derivative (PPD) in vitro. Purified T cells showed a lower response than the orginial purified lymphocyte suspension. Purified B cells were unresponsive to PPD. Mixtures of preparations of T and B cells were stimulated to a greater... | 126,490 | [
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... |
Light and electron microscopic observations on the carotid bodies of rats following adaptation to high altitude. | The carotid bodies of rats were investigated by light and electron microscopy following adaptation to a simulated altitude of 7000 m. Some animals were studied immediately after readaptation to sea-level, other groups up to 41 days later. The animals of the first group show enlarged glomera with dilated capillaries as ... | 126,519 | [
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0.01... |
Tissue specificity of the epidermal chalones. | An increasing body of evidence indicates that the rate of cell renewal in labile and stable cell populations is regulated according to a negative feedback principle. Water extracts of such tissues contain mitosis-inhibiting substances (chalones) that probably represent the chemical signals in these cell populations. Ti... | 126,520 | [
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0.2016342,
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0.07754967,
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Serum IgD and IgE in rheumatoid arthritis. | Serum immunoglobulins IgD and IgE have been determined by a single radial immunodiffusion technique and a radioimmunoassay method in serum samples from 95 rheumatoid patients, 5 subjects with Sjögren's syndrome and 50 healthy controls, and compared with levels of IgG, IgM and IgA fractions measured in the same subjects... | 126,543 | [
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-... |
Endotoxin-like properties of the peptidoglycan. | Peptidoglycan is responsible for the endotoxin-like properties of the streptococcus cell wall. The pyrogenic response of rabbit to group A streptococcus peptidoglycan prepared by hot formamide or TCA is dose-dependent and is increased if the material is ultrasonically solubilized. The pyrogenicity can be eliminated by ... | 126,556 | [
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0.4043332,
0.1669124,
0.1223464,
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... |
[The effect of dimethyl sulfoxide (DMSO) on the blood circulation in the pulp]. | The physiological and pathological regulatory mechanism of the endodontal blood circulation are demonstrated by means of vital microscopy with special respect to the specific vasoactivity of the DMSO. The authors' evaluation of the results includes discussion of the potentially utilizable effects of DMSO, but also the ... | 126,610 | [
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0.3... |
[The fluoride content in the crowns of molars following application of fluoride-containing toothpastes]. | The paper describes chemical-analytical research into the fluorine content in the coronal parts of molars of rats after fluoride tooth-pastes made up of differing ingredients were used. On the basis of the findings, recommendations are made as to ways of clinically testing the tooth-pastes. | 126,615 | [
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Mechanical performance of surgical sutures. | A comprehensive analysis of the mechanical performance of sutures has been made to provide information concerning the reliability and security of knotted sutures. The tests utilized in this analysis were designed to be easily reproduced by other investigators. The construction of the knot and the knot performance analy... | 126,649 | [
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[Generalization of the experience of programmed control of the knowledge of students in normal anatomy]. | Due to increasing significance of application of programmed control of knowledge in the process of teaching students the development and use of such method has been undertaken at the Department of Normal Anatomy of the Pavlov First Medical Institute since 1968 for examining students of the first and second year. The me... | 126,674 | [
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Glycosaminoglycans and acidic glycoproteins in rabbit uterus under estrogenic conditions. | Uterine slices obtained from the estrogen-treated rabbits were digested with pronase. Glycosaminoglycans and acidic glycopeptides were then isolated by Dowex 1 column chromatography and preparative electrophoresis on cellulose acetate membrane (Separax), in succession. Each subfraction thus obtained was identified by t... | 126,700 | [
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[Changes in rat hypothalamo-neurohypophyseal system after repeated ethanol administration]. | The histochemical, immunohistological and histoenzymatic study of the hypothalamo-neurohypophysial system of the rat shows that chronic ethanol administration induces: a temporary blockage of vasopressin synthesis, a vasoconstriction of the neurohypophysial capillaries, a dendritic storage of immunoreactive vasopressin... | 126,725 | [
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[Influence of interfering stimuli on contingent negative variation]. | The aim of this study was to examine the influence of interfering stimuli on subjects' C.N.V. With a labyrinthic stimulation before association S1-S2 and arithmetic calculation task between S1 and S2, the C.N.V. showed a statistically significant variation (P less than 0.025): it became prolonged after the response to ... | 126,726 | [
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[Changes in ventilatory patterns before and after vagotomy in rabbits]. | Ventilatory pattern have been investigated during rebreathing experiments. Before vagotomy, a linear relation has been found between increasing tidal volume and decreasing inspiratory and expiratory durations. After vagotomy, these relations existed but expiratory duration remained almost constant. | 126,729 | [
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[Depigmentizing effect of a glucocorticoid applied topically to black giunea pig skin]. | A 33 p. cent triamcinolone acetonide in DMSO is applied on the skin of black guinea-pig to ascertain its depigmenting potency. Its action is characterised by a marked, but incomplete, reduction of melanocytes in the epidermis and in the hair. A comparison is made with an other previously experimented corticosteroid. | 126,741 | [
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[Effect of cannabis on learning in the cynocephalic monkey (Papio Papio)]. | Chronic treatment of monkeys with Cannabis reduce the speed of acquisition of learned behavior, yet, learning is nevertheless possible. After acquisition, Cannabis administration disturb the responses in the learning test. In this two experimental procedures, tolerance occurs to the effects of Cannabis. | 126,742 | [
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[Iodoamino acid composition of rat thyroglobulin of varying total iodine concentration and fractions isolated by isopycnic ultracentrifugation]. | Iodoaminoacid content (iodothyronines, T3 and T4, and iodotyrosines, MIT and DIT) has been determined in enzymatic hydrolysates of thyroglobulin Tg 19S of different iodine content (0.3-0.9%) isolated from equilibrium labeled rats. Preparative equilibrium centrifugation in RbCl density gradients of pure thyroglobulin wa... | 126,748 | [
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[Effect of phenoxybenzamine, propranolol and guanethidine after repeated administration on nutritional blood flow in rats]. | In anesthetized rats, after i.p. treatment during 4 days: phenoxybenzamine and guanethidine were hypotensive and increased nutritional blood flow in squeletal muscles; propranolol had a poor hypotensive effect and decreased nutritional circulation in heart, skin and intestine. | 126,751 | [
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0.299102,
0.0166742... |
[Mathematical study of estrogen-progesterone antagonisms in the golden hamster]. | By the test of experimental deciduomata in the golden Hamster we have built a curve of hormonal antagonism between estradiol benzoate, and progesterone for growthing doses. The mathematical treatment of this curve allows a comparison with the figure of an enzymatic inhibition reaction. | 126,764 | [
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... |
[Study of sodium pump in erythrocytes with 22Na and 42K. I. Technics and results in normal people]. | An isotopic technique enabling the study of sodium and potassium flux rates in human red cells is reported. Nine normal patients have been studied for both isotopes. The results obtained are compared with those published in the literature. | 126,767 | [
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Aortic stenosis surgery in infancy. | During the past 14 years, 28 infants (23 males) underwent valvotomy for severe aortic stenosis at the Children's Hospital Medical Center in Boston. The median age was two months and the oldest patient was six months old. Congestive heart failure was present in all but two babies. Preoperatively, the electrocardiogram w... | 126,821 | [
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0.09... |
Hemodynamics and annuloplasty in isolated mitral regurgitation in children. | Isolated mitral insufficiency in children is quantitated angiographically by comparing the stroke volumes of the right ventricle and left ventricle. The disease results in greater enlargement of the left atrium than of the left ventricle and is accompanied by a significant increase in left atrial "distensibility." Righ... | 126,822 | [
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Rapidly progressive obstructive cardiomyopathy in infants with Noonan's syndrome. Report of two cases. | Two patients with hypertrophic obstructive cardiomyopathy and Noonan's syndrome are presented. Both patients were found at postmortem examination to have gross malformation of the mitral valve and obliteration of the left ventricle due to muscle hypertrophy. Each case demonstrated similar clinical, echocardiographic, a... | 126,823 | [
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The role of low affinity antibody in immune complex disease. The quantity of anti-DNA antibodies in NZB/W F1 hybrid mice. | The level and avidity of anti-DNA antibody in the serum of New Zealand Black/White (NZB/W F1) hybrid mice has been determined. The results show that there is an age and sex-related variation in the avidity of this antibody. In mice of both sexes, the avidity of circulating anti-DNA antibody increases up to 5 months of ... | 126,830 | [
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Characterisation of the major CNBr-Derived peptides of porcine type II collagen. | As part of a general study on the matrix macromolecules of pig cartilage, the CNBr-derived peptides of porcine type II collagen have been isolated from laryngeal cartilage and characterized. Type II was the only molecular type of collagen detected in laryngeal cartilage from 6-9 month old pigs. The major CNBr-peptides ... | 126,844 | [
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Effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats. | The effect of methysergide (MES, 2.5 mg/100 g body wt), a serotonin antagonist, on prolactin release has been studied in lactating and ovariectomized rats. MES caused significant increases in prolactin release in both animals. Studies in ovariectomized, hypophysectomized rats indicate that this effect is not due to a d... | 126,860 | [
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Amino-acid sequence of the cyanogen-bromide fragment from human plasminogen that forms the linkage between the plasmin chains. | The complete amino acid sequence of a cyanogen bromide fragment (122 residues) obtained from plasminogen is described. This fragment forms the overlap between heavy (A) and light (B) chains of human plasmin. The particular arginyl-valyl bond cleaved in the second step of the activation process is shown to be Arg98-Val9... | 126,863 | [
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Influence of 1,3-butanediol on blood glucose concentration and pancreatic insulin content of streptozotocin-diabetic rats. | Male rats were made diabetic by intravenous administration of 75 mg/kg of streptozotocin and were fed, via a pair-feeding regimen, high-fat diets +/- 1,3-butanediol (BD) at 13.5 and 27% of the dietary calories for 30 days and 31 days, respectively. 1,3-Butanediol was added to the diets primarily as a replacement for fa... | 126,871 | [
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... |
Ovarian delta-5-3-beta-hydroxysteroid dehydrogenase in aging rats. | Ovaries of rats 1, 2, 4, and 18 months old revealed significant delta-5-3-beta-hydroxysteroid dehydrogenase (3beta-OHSD) activity when dehydroepiandrosterone (DHA), pregnenolone, and 16-dehydropregnenolone served as substrates. No enzyme activity was evident in ovaries 4 and 18 months of age when the substrates 17alpha... | 126,872 | [
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0... |
The effects of thymidine and its analogues on the differentiation of antibody-forming cells. | Thymidine (Tdr) and its analogues 5-fluorodeoxyuridine (FUdr) and 5-bromodeoxyuridine (BUdr) inhibited the development of antibody-producing cells (PFC) in cultures of explants of rabbit spleen stimulated with sheep red cells in vitro. They were effective in this respect, even at concentrations too low to inhibit cell ... | 126,887 | [
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[Spontaneous peri-renal haematoma as a complication of chronic pyelonephritis]. | Three cases with spontaneous peri-renal haematomas, a rare complication of chronic pyelonephritis, are described. The clinical features and diagnosis of this condition are discussed with reference to these cases and the literature is reviewed. | 126,897 | [
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[Calcium "milk" in the kidney. (Five cases with hydronephrotic kidney)]. | A study of the literature has revealed 11 cases of calcium "milk" in hydronephroses. We have been able to observe five further cases in a period of 14 months. The criteria annunciated by Murray are stressed, since they will raise a suspicion of the presence of calcium "milk" on views taken with a vertical x-ray beam. I... | 126,898 | [
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0.5090867,
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[Neuromas and myomas of the stomach]. | Seven non-epithelial benign tumours of the stomach are described. The clinical and radiological features are compared with those described in the literature. Since it is not always possible to be certain of the benign nature of the lesion, and since they may give rise to life-threatening bleeding, resection is indicate... | 126,909 | [
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-0.1711784,
-0.00535017... |
[Roentgen kymographic investigations of gastric peristalsis after intravenous injection of caerulein]. | Caerulein is a decapeptide which combines the effects of gastrin and cholecystokinin-pancreozymin. It was injected intravenously in doses of 10 to 40 nanoponds caerulein per kilopond bodyweight in 37 patients and roentgen kymography of the stomach carried out before and after the injection. In 89% of the 36 cases which... | 126,910 | [
-0.07515233,
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0.08710944,
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0.4262964,
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0.2368648,
0.1280813,
0.1386499,
-0.2... |
[Endobronchial brush biopsy]. | Bronchial brushing under fluoroscopy control is used in the diagnosis of pulmonary lesions which are beyond reach of the bronchoscope. A small nylon or steel brush is passed through a bronchial catheter and tissue material from the lesion is taken for cytologic and bacteriologic studies. The technique described is easy... | 126,922 | [
0.005160307,
0.1473877,
0.02061915,
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0.3303196,
0.1266453,
0.1232557,
0.5750892,
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-0.0739581,... |
[New bases and theories from improving angio-cine-densitometry. II Improvements in the signal-to-noise ratio by the quotient method in cine densitometry]. | In radio-cine-densitometry, random variations can be smoothed and reduced in two ways: temporal (frame to frame) and spatial (each frame). Both methods may, however, alter the signal measurements. The advantage of quotient cine-densitometry depends on the elimination of interference or random variations without changin... | 126,934 | [
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0.2622283,
0.4882451,
0.2400992,
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0... |
Conformational differences in myosin, IV.[1-3] Radioactive labeling of specific thiol groups as influenced by ligand binding. | Changes in the mono- and divalentcation-stimulated ATPase activities of myosin progressively labeled with N-ethyl-[2,3-14C2]-maleimide were used to classify the readily reacting thiol groups into 3 types. The results show that one thiol-1 and one thiol-2 group are associated with each of the 2 active sites of myosin. C... | 126,941 | [
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0.3457345,
0.5532957,
0.2118181,
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0.... |
The effect of vitamin E deficiency on androgen and corticosterone synthesis. | The incorporation of 14C-cholesterol into total androgens by testis homogenates and into total androgens and corticosterone by adrenal homogenates was measured in tissues taken from rats deficient in vitamin E, and from rats given vitamin E, from weaning to a maximum of 293 days. The peak of incorporation of 14C into a... | 126,972 | [
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0.06246012,
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0.317227,
0.3663322,
0.1532501,
0.05446308,
0.0... |
Studies on steroids. III. A new type of derivative for electron capture-gas chromatography of ketosteroids. | Pentafluorobenzyloxyamine is presented as a new derivatizing agent for gas chromatography of ketones using electron capture detection. The typical 17-ketosteroid was readily transformed into the O-pentafluorobenzyloxime which on usual trimethylsilylation led to a 3-trimethylsilyl ether derivative exhibiting good gas ch... | 127,001 | [
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0.4641035,
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0.1985805,
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0.3208516,
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0.1886727,
0.2076902,
0.0745669,
0.1382611,
0.2549264,
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0.1... |
Immediate-type hypersensitivity to a bean lectin source with commentary on occupational allergy in allergy-immunology laboratory and research workers. | A case of acute, severe allergic conjunctivitis is reported in a biochemist who had been grinding Bandeiraea simplicifolia, the source of an anti-B lectin. A crude extract of these beans produced immediate-type skin test reactivity, and reaginic antibodies were demonstrated in her serum. Several other examples of occup... | 127,006 | [
0.1099679,
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0.3336944,
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0.2159357,
0.3049312,
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0.4855347,
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Generation of cytotoxic T lymphocytes in vitro. VI. Effect of cell density on response in mixed leukocyte cultures. | Reexposure of day 14 murine mixed leukocyte culture (MLC) populations to the original irradiated allogeneic stimulating spleen cells has previously been found to result in the ratpid generation of cytolytic T lymphocytes (CTL) associated with a net increase in cultured cell number. Under the experimental conditions use... | 127,012 | [
-0.1253742,
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0.5025377,
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0.3609702,
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0.2433846,
0.3385022,
0.3508352,
-0.00365020... |
Effects of various drugs on serum free and total tryptophan levels and brain tryptophan metabolism in rats. | Various drugs known to bind to serum albumin were examined to determine whether or not they influenced the level of free tryptophan in serum in vitro and in vivo. Possible relationships between the serum free tryptophan level and serotonin (5-HT) synthesis in the brain and the hypothermic effects of these drugs were in... | 127,058 | [
-0.154333,
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0.03826263,
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0.5081915,
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0.2813329,
-0.2315229,
0... |
[The chromosomal syndromes (author's transl)]. | Considering the results of modern cytogenetics in the area of chromosomal abberation, we can adopt without restriction two demands formulated by G. Koch (1971). First, further systematic research on mentally subnormal children should be carried out to clarify whether forms of chromosomal-genetic abnormality based on pr... | 127,145 | [
-0.01496996,
0.04019893,
0.1029415,
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0.1849842,
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0.2376027,
0.1920718,
0.2900788,
0.2932748,
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0.1949251,
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-0.3617708,
-0.08074629,
0.1178029,
-0.09221704,
0.1928983,
0.03028445,
-0.1550927,... |
[Clinical aspects of chromosomal aberrations - problems of semiotics and nosography]. | Despite intense clinical and cytogenetic research for more than 15 years we are far from knowing any definite relations between karyotype and phenotype. Both cytogeneticists and clinicians are working on the methodological improvements which are still necessary. In the methods of clinical recording there is still very ... | 127,146 | [
0.06575891,
0.2076872,
0.3297842,
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0.4949541,
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0.1741899,
0.1716095,
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0.2957645,
0.3765393,
-0.1707335,
-... |
[Investigations of erythrocyte metabolism in trisomy 21 (author's transl)]. | Although the present studies were carried out in a large number of patients, it is not possible to say wether (and what kind of) enzymes are genetically fixed on chromosome 21. It is to be hoped that further studies on the question of enzyme localization, particularly of phosphofructokinase, will afford some clarificat... | 127,151 | [
-0.1122233,
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0.01324588,
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0.1627191,
0.00795992,
0.06997345,
0.5193769,
0.2880634,
-0.2805343,
-... |
[Experience in the control of the mosquito Culex pipiens molestus Forsk. In Leningrad]. | Systematic control of mosquitoes (C. p. molestus) has begun in Leningrad since 1968 when undertaken inspections revealed mosquitoes and their aquatic stages in 21.8% of basements. All hatching sites of mosquitoes were registered and sanitary, hydrotechnical and destroying measures were carried out there. During the per... | 127,154 | [
-0.0115855,
0.2578135,
0.02973887,
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0.0218735,
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0.2793124,
0.1681141,
0.1216787,
0.1827156,
0.1089595,
-0.2844342,
... |
The Hurler syndrome: treatment of cultured Hurler fibroblasts with normal human serum. | Prolonged replacement of fetal calf serum by normal human serum for the enrichment of medium during tissue culture of Hurler fibroblasts resulted in increased acid mucopolysaccharides in the cells and in the medium. The predominant intracellular mucopolysaccharide had the characteristics of dermatan sulfate when Hurler... | 127,180 | [
-0.002246029,
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0.2401899,
0.393044,
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0.3062328,
0.2402588,
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0.1025388,
0.1586576,
0.001102041,
-0.09306283,... |
Specific dynamic action of a high-protein diet and its significance for thermoregulation in the golden hamster. | As a result of the specific dynamic action of a high-protein diet the resting metabolism of golden hamsters within the zone of thermoneutrality is increased on a average by 40%. The specific dynamic action diminishes markedly, with declining environmental temperature. It is concluded from this results that part of the ... | 127,188 | [
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0.2456114,
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0.2431811,
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0.04923459,
0.001434577,
0.1900287,
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0.05558922,
-0.01715833,
0.3631158,
-0.075... |
[Our experience in the treatment of pseudarthrosis of the carpal schaphoid bone]. | The present paper reports on 20 cases of old fractures and pseudoarthrosis of the carpal scaphoid operated in the Clinic of Ortopaedics and Traumatology of the "Brîncovenesc" Hospital and followed up over an 8 year period (1965--1972). The treatment, exclusively surgical, consisted in: osteosynthesis with corticospongi... | 127,195 | [
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0.1808199,
0.3230759,
0.1373686,
0.06240429,
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0.1949011,
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0.03861845,
0.07033955,
0.130975,
0.2390899,
0.2532415,
0.09216566,
0.009933544,
0.12312... |
Another look at Pereyra's stint urethropexy. | Twenty-five women with stress incontinence had stint urethropexy as described by Pereyra. Unqualified success was achieved in only 53%. These cases are analyzed and criteria suggested for selecting patients suitable for stint urethropexy. | 127,387 | [
0.09096463,
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-0.2872915,
0.03069413,
-0.3235729,
-0.2432252,
0.1495439,
0.2679141,
-0.0239... |
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