title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Ischemic papilledema in giant-cell arteritis. Mucopolysaccharide deposition with normal intraocular pressure. | A 68-year-old man died 18 days after the onset of ischemic optic neuropathy caused by histologically proven giant-cell arteritis. On histopathologic study of the eye, ischemic necrosis of the prelaminar and retrolaminar optic nerve was seen, along with the massive presence of acid mucopolysaccharides sensitive to testi... | 131,544 | [
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Total correction of type I truncus arteriosus in a 6-month-old infant. | A successful correction of type I truncus arteriosus using a 12 mm 'dacron' conduit containing a porcine aortic valve (Hancock) between the right ventricle and the pulmonary artery in a 6-month-old infant is reported. The rationale for the treatment of truncus arteriosus in infancy is discussed. | 131,565 | [
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Immunological studies in Rockland mice infected with T. cruzi. Development of antinuclear antibodies. | The existence of antinuclear antibodies (ANA) and their relationship with anti-Trypanosoma cruzi specific agglutinins was studied in Rockland mice inoculated with 10(5), 10(4) or 10(3) epimastigotes and 2 X 10(5) trypomastigotes of T. cruzi. ANA and anti-T. cruzi agglutinins were detected at the same time in groups of ... | 131,587 | [
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[Compensatory renal hypertrophy in rats. II. Possible regulatory role of renal inhibitory substance]. | Clear supernatant from kidney homogenate injected to an uninephrectomized rat inhibits specifically the incorporation of tritiated thymidine by compensating kidney. This result agrees with the speculation of autoregulation of kidney growth. | 131,606 | [
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[Seasonal variation of arylesterase activity and its consequence for enzymatic hydrolysis of phenylacetate]. | Studies on red cell arylesterase activity were performed for two years by potentiometric titration using phenylacetate as substrate. From April to October enzymes had higher arylesterase activity than the rest of the year. During that period an increase of arylesterase activity by L-phyenyl-alanine had not been shown. | 131,635 | [
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[Effect of d-1 propranolol on urinary osmolarity after furosemide in anesthesized dog]. | The effects of propranolol (l mg/kg/H infused in the renal artery) on the diuretic action of furosemide (20 mg/kg i.v.) have been studied in pentobarbital anesthetized dogs. We obtained the 3 following results : the urine remained isotonic to the plasma during the 6 hours following the furosemide injection ; the urinar... | 131,638 | [
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Clinical diagnosis of Down's syndrome. | A physical examination checklist of 25 signs of Down's syndrome was used to predict the presence of absence of 21-trisomy in 291 individuals examined for suspected Downs syndrome. Using only total numbers of signs present, 21-trisomy was unambiguously predicted in about half those examined. Discriminant analysis using ... | 131,663 | [
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The cyanogen bromide peptides of bovine soluble and insoluble collagens. II. Tissue specific cross-linked peptides of insoluble skin and dentin collagen. | Cyanogen bromide peptides were prepared from insoluble bovine skin and dentin collagens and compared by electrophoresis in polyacrylamide gels containing sodium dodecylsulphate, with those of the alpha1 and alpha2 chains of soluble type I and type III collagen. Both insoluble collagens yielded predominantly the peptide... | 131,673 | [
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[Effect of leukemic sera on the reactivity of leukocytes from acute leukemia patients in mixed lymphocyte cultures]. | The author examined the action of leucemic sera (first attack, repapse and remission) on the reactivity of lymphocytes, obtained from patients with acute myeloblastic (AML) in mixed cultures of lymphocytes, which was compared with the reactivity in the medium of fetal calf serum and pool of normal human serum. Twelve o... | 131,683 | [
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Evidence for a new intermediate state in the mechanism of (Na+ + K+)-adenosine triphosphatase. | A rapid mixing technique was used to follow the intermediate formation of phosphorylated enzyme and liberation of inorganic phosphate by a microsomal preparation of (Na+ + K+)-ATPase. In the presence of 100 mM Na+,but without added K+, phosphorylation reaches a constant level at a rate which is dependent on ATP concent... | 131,800 | [
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Early events during substrate adhesion of normal and virus-transformed mouse fibroblasts. | The relationship between attachment of Balb/c3T3 cells and their SV40 transformants to glass or plastic substrates and deposition of substrate-attached material (SAM-proteoglycans implicated in substrate adhesion) has been examined very early after inoculation of cells subcultured with ethylenebis (oxyethylenenitrilo) ... | 131,809 | [
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The use of spontaneously hypertensive rats for the study of anti-hypertensive agents. | Hypertension studies using laboratory animals have been conducted since 1930. These were not completely satisfactory because either surgery or pharmacologic induction were required to produce hypertensive animals. Many attempts have been made to breed spontaneously hypertensive rats, mainly from the Okamoto strain. The... | 131,878 | [
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Surgical treatment of floppy mitral valve syndrome in children. | Five children whose ages ranged from 9 to 14 years underwent operation for floppy mitral valve syndrome. The clinical course of this syndrome in young patients was characterized by exceptionally rapid deterioration in congestive heart failure after the onset of symptoms. The children responded poorly to medical treatme... | 131,884 | [
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[Microflora of underground waters in oil and gas fields of Mangyshlak]. | The distribution of various physiological bacterial groups with respect to the geological profile and area was studied in underground waters of the gas and oil bearing complexes of Mangyshlak. Metamorphism of the environment in the complexes, in the direction of flow of underground waters, from the oxidative to the red... | 131,900 | [
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[Influence of vitamin A on the distribution of glycosaminoglycans in rat tissues]. | Glycosaminoglycans (GAG) from brains, intestines, livers and skin of rats were analyzed by electrophoretic and enzymatic methods. Variations in GAG distribution have been studied in rats fed on a vitamin-A-deficient diet and on a diet supplemented with an excessive quantity of vitamin A. Hypervitaminosis A resulted in ... | 131,915 | [
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DNA methylase: purification from ascites cells and the effect of various DNA substrates on its activity. | DNA methylase has been purified 405-fold from Krebs II ascites cells. The purified enzyme is homogeneous on SDS-poly acrylamide gel electrophoresis (molecular weight about 80,000) and the only product of the reaction with DNA is 5-methyl cytosine. Both native and denatured DNA are methylated by the enzyme; with calf th... | 131,936 | [
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Transplacental effects of nitrosamines in Syrian hamsters: I. Dibutylnitrosamine and nitrosohexamethyleneimine. | The transplacental carcinogenic effects of dibutylnitrosamine (DBN) and nitrosohexamethyleneimine (N-6-MI) were examined in Syrian hamsters. A proportion of both substances reached the fetal tissue unaltered. No macroscopic malformations were observed in the offspring; however, postnatal mortality was high. Respiratory... | 132,030 | [
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Carcinogenic effects of different nitroso-compounds in Chinese hamsters. II. N-nitrosomorpholine and N-nitrosopiperidine. | A total of 320 Chinese hamsters (Cricetulus griseus) (CH) were subcutaneously (s.c.) treated with 1/5, 1/10, or 1/20 LD50 of N-nitrosomorpholine (NM) or N-nitrosopiperidine (NP). In the CH, NM and NP both produced up to a 100% rate of papillomas of the cheek pouch, tongue, pharynx, esophagus and forestomach. Occasional... | 132,034 | [
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The chlorophyll aII reaction in trypsin-treated spinach chloroplasts in the presence of potassium ferricyanide. | In trypsin-treated spinach chloroplasts there is no linear electron flow from water to potassium ferricyanide. The chlorophyll aII reaction, however, is still active but insensitive to 3-(3, 4-dichlorophenyl)-1, 1-dimethylurea. From this we conclude that ferricyanide and trypsin together stimulate a mini-cycle in photo... | 132,043 | [
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[Chromosomal structures of Pseudomonas testosteroni. I. Isolation and characterization of the chromosomal complexes. (author's transl)]. | After lysis of Pseydomonas testosteroni with lysozyme and non-ionic detergents different DNA-protein complexes can be separated in 5-25% (w/v) neutral sucrose gradient. The protein to DNA ratio of these complexes varies between 0.5-4.5 to 1, whereby the faster sedimenting forms contain more protein than the slower sedi... | 132,046 | [
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In vitro studies on target cells of oncogenic adenoviruses in hamster brain. III. In vitro transformation of brain cells of hamsters at various ages by bovine adenovirus type 3. | In vitro transformation of brain cells of hamsters at various ages was examined after the addition of bovine adenovirus type 3 to determine the type and origin of the target cells. Cellular transformations occurred only in cultures of fetus and newborn animals and at low incidences. Nine cell lines were obtained. Virus... | 132,085 | [
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Inhibitory effects of glucocorticoids on prolactin release induced by thyrotropin-releasing hormone in man. | Glucocorticoid effect on thyrotropin-releasing hormone (TRH)-induced prolactin (PRL) release was studied in female patients with collagen or autoimmune diseases. Long-term, high dose glucocorticoid therapy tended to inhibit the response of plasma PRL to TRH. A negative correlation (r=-0.40) was found between the logari... | 132,086 | [
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Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria. | Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was observed by adding purine- and pyrimidine nucleosides. The phosph... | 132,087 | [
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Cutaneous reactions to propranolol (Inderal). | Six patients wit psoriasiform cutaneous eruptions that developed during long-term therapy with propranolol (Inderal) have been studied. The cutaneous changes closely resembled those seen during treatment with practolol (Eraldin). The duration of treatment before the rash was recognized averaged 10 months, which is abou... | 132,088 | [
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[Partial trisomy 21 (21q21 - 21q22.2)]. | An abnormal chromosome 21 is reported in a child with a phenotype strongly reminiscent of trisomy 21 syndrome. It is shown to result from duplication of the segment 21q21 leads to 21q22.2. Comparison of the phenotype with that of other partial and total trisomics shows that the characteristic features of the trisomy 21... | 132,130 | [
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DNA repair and frequency of x-ray and u.v.-light induced chromosome aberrations in leukocytes from patients with Down's syndrome. | DNA-repair and the frequency of chromosome aberration after u.v. and X-ray irradiation was studied on leukocytes from patients with Down's syndrome. The u.v.-induced DNA-repair synthesis was followed by the incorporation of [3H]thymidine in the presence of hydroxyurea. Similar dose-response curves were established for ... | 132,131 | [
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[Comparative study of the antibiotic sensitivity of Proteus hauseri bacteria belonging to different serological groups]. | Sensitivity to 9 antibiotics of 1040 strains of Proteus belonging to the serological groups 03, 05, 06, 07, 010, 011, 013, 023, 024, 026, 027, 028 and 030 was studied. It was found that the above strains were sensitive and highly sensitive to the aminoglycosides and streptomycin, slightly sensitive to levomycetin and r... | 132,135 | [
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Topical vitamin A acid in the treatment of acne vulgaris (a controlled multicenter trial). | A controlled non-blind multicenter trial was conducted in 211 acne patients to test the activity of topical retinoic acid against sulfur-resorcinol--salicylic acid and placebo. Uniform evaluation criteria were used. After 8 weeks' treatment in comparable groups of patients, retinoic acid proved to be superior to the st... | 132,142 | [
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0.0493401,
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0.01021534,
0.03178591,
-0.14898... |
Placental metabolism of dehydroepiandrosterone sulphate in normal pregnancy. | An intravenous injection of 50 mg dehydroepiandrosterone was given to 19 women at the 38th week of pregnancy. The concentration of androstenedione, testosterone, oestradiol and oestrone in plasma was measured at intervals following the injection. The concentration of androstenedione and testosterone rose rapidly; reach... | 132,184 | [
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0.1469772,
0.2595282,
0.5182064,
0.08633713... |
Inhibition of energy-transducing functions of chloroplast membranes by lipophilic iron chelators. | Lipophilic metal chelators inhibit various energy-transducing functions of chloroplasts. The following observations were made 1. Photophosphorylation coupled to any known mode of electron transfer, i.e. whole-chain noncyclic, the partial noncyclic Photosystem I or Photosystem II reactions, or cyclic, is inhibited by se... | 132,188 | [
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0.1674263,
-0.209929... |
[Vectorcardiography]. | The principle of vectorcardiography is first discussed. The setting out in space is very instructive. An over-valuation of slight vectorcardiographic changes can lead to wrong conclusions. The changes in right hypertrophy may in many cases be important for diagnosis. This is true for cases of intraventricular conductio... | 132,212 | [
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... |
[Comparative morphometric data on the epiphysis, the subfornical organ, and the anterior pituitary gland in 2 groups of pure strain Wistar female rats, SPF or conventional]. | In SPF female rats, the pineal gland is less voluminous and its cell-nuclei are smaller than those of conventionnal female rats. This confirms (with the voluminous adrenals previously reported) the stressing action of the absence of pathogenic germs on these animals. The anterior lobe of the hypophysis is slightly smal... | 132,229 | [
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0.02918061,
0.2362494,
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[Electromyographic analysis of motor perturbations linked with gastrointestinal strongyloidiasis]. | The effects of experimental infection of lambs with third stage Trichostrongylus larvae are described. Preceding diarrhea, disturbances in the motility of the reticulum, abomasum and jejunum were observed by electromyography. Disappearance of the migrating myoelectric complexes occurred about 24 h before diarrhea and w... | 132,260 | [
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0.4588382,
-0.02211735,
0.0243... |
Decreased ability of blood leukocytes from patients with tumors of the urinary bladder to act as stimulator cells in mixed leukocyte culture. | Blood leukocytes from patients with active neoplasms of the urinary bladder were found to have a decreased ability to stimulate in one-way mixed leukocyte culture (MLC). The ability of the patients' leukocytes to act as stimulator cells in one-way MLC was assessed by simultaneous comparison to the ability of leukocytes... | 132,272 | [
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0.08602862,
0.06071419,... |
[Liver metastases: diagnostic value of blood tests, scintiscanning, and laparoscopy (author's transl)]. | In 90 patients with known extra-hepatic malignancy the liver was examined for metastases. The diagnostic value of clinical information, blood examinations, 99mTc scintiscan, and laparoscopy for the diagnosis of the liver metastases was evaluated. Clinical data (age, sex, time since onset of symptoms and localisation of... | 132,343 | [
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Nutrition in the practice of pediatric dentistry. | Nutrition is an important aspect of the total environment of a growing child. The dentist should evaluate the nutrition of pediatric patients from the physical parameters of the child including growth, general appearance, posture, muscle control, oral findings, and dietary history. Some common malnutrition problems of ... | 132,377 | [
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0.3856758,
0.4931838,
-0.245240... |
Three new species of Gyrodactylus (Monogenoidea) from Varicorhinus capoeta gracilis (Keyserling) from the River Lenkoranka. | Three new species of Gyrodactylus Nordmann, 1832 are described from Varicorhinus capoeta gracilis (Keyserling) from the River Lenkoranka (Azebaijan SSR) as follows: G. varicorhini sp. n., G. capoetai sp.n. and G. mikailovi sp.n. | 132,393 | [
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0.1613372,
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0... |
Temperature-dependent transitions of the myosin-product intermediate at 10 degrees during Mn(II)-ATP hydrolysis by myosin from rabbit psoas muscle. | The initial burst of Pi liberation during the hydrolysis of Mn(II)-ATP by heavy meromyosin from rabbit psoas muscle was investigated. Below 10 degrees, the initial burst of Pi liberation was inhibited by the pre-addition of ADP without any change in the steady-state activity, but it was not inhibited above 10 degrees. ... | 132,432 | [
-0.2353399,
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0.1080507,
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0.8230418,
0.06539501,
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0... |
Histones of Neurospora crassa. | Neurospora crassa chromatin isolated by a rapid method minimizing proteolytic degradation contains approximately one weight of acid-extractable basic protein per weight of DNA. This basic protein consists of five major polypeptide species which are similar in size to the histone proteins of higher eukaryotes and are pr... | 132,444 | [
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... |
Surgical correction of intertriginous soft corns. | A new surgical technique for the excision of intertriginous soft corns with advancement of the floor of toe webs is presented. | 132,463 | [
-0.0298374,
0.138064,
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... |
Simultaneous localization of proteoglycan by light and electron microscopy using toluidine blue O. A study of epiphyseal cartilage. | The simultaneous localization of proteoglycan by light and electron microscopy was demonstrated by fixing epiphyseal cartilage in a glutaraldehyde toluidine blue O solution. Sections cut for light microscopy viewing and those cut for electron microscopy required no further staining, although, in the latter case, staini... | 132,503 | [
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0.1468035,
0.3116013,
0.06900066,
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... |
Acetylcholine and choline in cerebrospinal fluid of patients with Parkinson's disease and Huntington's chorea. | Lumbar cerebrospinal fluid (CSF) acetylcholine (ACh) and choline (Ch) levels were measured in patients with Huntington's chorea (N=11), Parkinson's disease (N=8), and subjects at risk for Huntington's chorea (N=4), and all three groups were found not to differ significantly from normal controls (N=10). The values found... | 132,512 | [
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0.3010912,
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0.2496651,
-0.007775774,
-0.02807896,
0.1257... |
Scalp hair patterns in mental subnormality. | Scalp hair patterns have been examined in 1901 healthy subjects and 1789 severely subnormal patients. Patients with Down's syndrome had a highly significant excess of midline occipital whorls and a deficit of right-sided occipital whorls. Five out of 44 patients with microcephaly had a distinct 'up-sweep' of the fronta... | 132,531 | [
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0.174647,
0.2840503,
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... |
Patch aortoplasty for insertion of the porcine heterograft. | The porcine heterograft has been shown to be a very satisfactory replacement for the diseased aortic valve. In certain cases, the advantage of a low thromboembolism rate without anticoagulation must be weighed against the suboptimal orifice size noted in the smallest heterografts. In using the largest replacement possi... | 132,580 | [
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0.3638589,
0.2143712,
0.1351852,
... |
[Pathophysiological implications of antigen-antibody complexes (author's transl)]. | Seventy years after the description of the Arthus phenomenon, the concept of immune complex mediated pathology is widely recognized in clinical pathophysiology. The availability of methods for the detection of soluble immune complexes opens new paths for clinical investigation in this field. This is demonstrated for sy... | 132,628 | [
0.1011938,
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0.3899852,
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... |
Developments in histocompatibility testing. | Recent progress in HLA typing involves new methods which allow typing for MLC (mixed lymphocyte culture) and Ia (immune associated) antigens. These antigens seem to play a major role in transplant rejection in HLA non-immunised patients. When the new typing methods eventually become applied in matching of kidneys it se... | 132,660 | [
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0.1812899,
0.3032261,
0.02538596,
-0.110006... |
Hyperglycemic activity of some non-nitrosated streptozotocin analogs. | Six non-nitrosated and three nitrosated analogs of the antitumor and diabetogenic agent, streptozotocin, have been found to produce hyperglycemia in fasted rats. The hyperglycemia produced by the non-nitrostaed analogs was of early onset and did not result in the production of permanent diabetes. The data emphasizes th... | 132,666 | [
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0.1854091,
0.168556,
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0... |
Effect of deoxycorticosterone acetate and 16beta-hydroxy-dehydroepiandrosterone on blood pressure and plasma renin activity of rats. | Intact female Sprague-Dawley rats were given daily injections of either 3.125 mg of deoxycorticosterone or 5.0 mg of 16beta-hydroxy-dehydroepiandrosterone, calculated from the activities reported for each to be equivalent mineralocorticoid dosages. The former caused hypertension, cardiorenal enlargement, increased urin... | 132,667 | [
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0.2748877,
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0.3226368,
-0.01687439,
-... |
Enhancement of insulin secretion by human chorionic somatomammotropin and related hormones. | Hypophysectomized rats were treated for 6 days with 200 mug per day of either human chorionic somatomammotropin, human pituitary growth hormone, plasmin-modified human pituitary growth hormone, or ovine prolactin. All hormone preparations except ovine prolactin enhanced the ability of the pancreases of hypophysectomize... | 132,669 | [
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0.08960269,
0.002525116,
0.09488399,
0.0... |
Copulation in noncopulators: effect of PCPA in male rats. | Twenty eight virgin male rats who failed to mount spontaneously on four successive mating tests were randomly assigned to two equal groups. One group received four daily injections of PCPA (100 mg/kg-IP), and the other, four vehicle injections. About 24 hr after the last injection all rats were subjected to a mating te... | 132,671 | [
-0.00885393,
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0.090655,
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0.1230012,
0.1253593,
... |
Gastrointestinal blood loss on phenylbutazone and feprazone. | Feprazone, a new anti-inflammatory drug, is a useful antirheumatic preparation which causes little gastrointestinal upset. This short cross-over study shows no significant gastrointestinal blood loss with either feprazone or phenylbutazone by the red-cell chromium-51 labelling method. | 132,693 | [
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... |
Muscle fiber composition in patients with traumatic cord lesion. | Muscle fiber composition and oxidative and glycolytic enzymatic activity have been studied with complete traumatic transection of the spinal cord and spastic paralysis of the lower extremities. Muscle sample were taken by means of needle biopsy from the vastus lateralis, gastrocnemius, and soleus muscles. Biopsies were... | 132,700 | [
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0.3209295,
0.694582,
0.2842488,
0.02222101,... |
[Aging--risk factor for arteriosclerosis]. | The changes of the arteries appearing diffusely caused by ageing as a rule favour the development of the focal arteriosclerotic changes. Already due to the increasing blood lipid level the ageing vessel is exposed to increased loads. It is more difficult for it to cope with them, since caused by ageing the cell functio... | 132,778 | [
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0.3802802,
0.2451259,
0.2472096,
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-0... |
The significance of intraventricular electrocardiogram in artificial heart pacing. Observations made on 232 patients. | From 1972-1975, 232 consecutive patients suffering from A/V block were paced intravenously in the Cardiac Department. Medical School, University of Athens. Of these, 124 were female and 108 male. Their age range was between 49 and 85 years. Besides fluoroscopic and threshold control, the intraventricular electrocardiog... | 132,833 | [
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0.472612,
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0.0953... |
Protein synthesis in heart mitochondria: mechanism and metabolic aspects. | A short review is given with respect to the status quo of the knowledge of mitochondrial protein synthesis in mammalian tissues. The inhibitory effects of antibiotic such as chloramphenicol and thiamphenicol are discussed from the point of possible complications for cardiac metabolism. It is shown that a decrease of th... | 132,834 | [
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0.04571972,
0.2264397,
0.3093269,
-0.1606195,... |
Acupuncture and transcutaneous electric stimulation in the treatment of chronic sacrolumbalgia and ischialgia. | A comparison was made between 50 patients treated with acupuncture and 50 patients treated with transcutaneous electric stimulation. All patients suffered from chronic sacrolumbalgia or ischialgia of more than six months' duration. Two to 10 treatments were given at weekly sessions, the mean being 5 in both groups. Sti... | 132,863 | [
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0.1129353,... |
Muscle damage produced by chronic alcohol consumption. | The effects of chronic alcohol consumption on skeletal muscle, independent of nutritional factors, were studied. Chronic alcohol ingestion led to striking ultrastructural changes in skeletal muscle, including intracellular edema, enlarged and distorted mitochondria, dilatation of sarcoplasmic reticulum, and increased a... | 132,869 | [
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0.2652446,
0.04445966,... |
The effort to rehabilitate workers' compensation. | State workers' compensation laws have been subjected to criticism since their inception; pressure to change them is now increasing. Most of the current challenge arise from dissatisfaction with the level of benefits available to disabled workers or their survivors, and, to a lesser degree, with the extent of program co... | 132,873 | [
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... |
Immunologic reactions in penicillin factory workers. | One hundred sixty-nine employees of a synthetic penicillin plant participated in this study to correlate immunologic reactions, allergic symptomatology and dustiness of the work area. Statistically significant positive correlations existed among the following: (1)presence or absence of symptomatology and increasing dus... | 132,880 | [
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-... |
Improved method of assay for choline. | A modified assay for choline is described which is shorter, yields more consistent responses, and requires considerably less time, space, and equipment than the existing assays. | 132,893 | [
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Disabled counselors: perception of their effectiveness in a therapeutic relationship. | It has not been delineated how a disabled person is viewed when interacting with another person. The present study investigated subject perception of a counselor in a wheelchair who was seen in a video-taped counseling interview. Subject degree of body satisfaction was measured to assess the importance of this variable... | 132,910 | [
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[Cytologic diagnosis of stomach polyps]. | Cytological and cytochemical studies of smears, taken during gastrofibroscopy in 36 patients with polyps of the stomach, with the aim to ascertain cytological and cytochemical characteristics of gastric polyps depending upon their histological structure were carried out. It was established that in the case of simple gl... | 132,912 | [
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[Oil keratoses and scrotal cancer, an avoidable occupational disease of the metal turner]. | Report of a 39 year old lathe worker which suffered from oil acne 10 years ago. The disease was registrated as occupational dermatosis. It healed up after the patient changed to a plant with better conditions of work. Pitch warts on the scrotum remained and were failed to notice. Multiple scrotal carcinomas developed m... | 132,929 | [
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0.1322277,
0.3691368,
0.2922861,
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... |
Glycosaminoglycans and proteoglycans of human chondrosarcoma. | The glycosaminoglycans and proteoglycans of a human chondrosarcoma have been studied. Glycosaminoglycans were fractionated and identified by cetylpirdium chloride (CPC) cellulose chromatography, ECTEOLA cellulose ion-exchange chromatography and electrophoresis on cellulose acetate. Proteoglycans were extracted by low i... | 132,969 | [
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0.4675379,
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0.1292609,
... |
A method for the quantitative determination of urinary glycosaminoglycans. | A method is presented by which the urinary glycosaminoglycans can be isolated in a macromolecular fraction with complete recovery by preparative gel filtration. The urinary glycosaminoglycans can be quantitated by determinations of uronic acid and sulfaminohexose in the macromolecular fraction. Using untreated, random ... | 133,005 | [
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0.0391831,
0.3122917,
0.02104019,
-0.0029635... |
Pyrogen fever in rabbits pretreated with p-chlorophenylalanine or 5, 6-dihydroxytryptamine. | The hyperthermic effect of a bacterial pyrogen has been studied in rabbits pretreated or not with p-chlorophenylalanine or 5, 6-dihydroxytryptamine. The results obtained indicate that a selective reduction of cerebral 5-hydroxytryptamine levels by these drugs do not significantly affect pyrogen hypertermia. | 133,031 | [
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0.... |
Studies of tryptophan and albumin metabolism in a patient with carcinoid syndrome, pellagra, and hypoproteinemia. | Detailed studies of protein metabolism were undertaken in a patient with pellagra and hypoproteinemia associated with the carcinoid syndrome both before and after treatment. The synthesis of albumin improved from 82 mg per kg per day to 135 mg per kg per day with little change in the daily excretion of 5-hydroxyindole ... | 133,045 | [
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... |
Intrafusal fibre types in rat limb muscle spindles: morphological and histochemical characteristics. | Morphological, histochemical and ultrastructural characteristics of intrafusal fibre types were studied in rat muscle spindles. The existence of three intrafusal fibre types, namely the typical bag, the intermediate bag and the chain fibres was confirmed. Intrafusal fibres differ in diameter, length and number of nucle... | 133,085 | [
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Retention and degradation of 125I-insulin by perfused livers from diabetic rats. | The retention of degradation of insulin by isolated perfused liver have been examined. Noncyclically perfused livers from streptozotocin-diabetic rats retained 25% and degraded 10% of 125I-insulin administered as a 1-min pulse. On gel filtration (Sephadex G50F), the degradation products released into the vascular efflu... | 133,120 | [
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... |
Intrarenal distribution and ATPase inhibiting activity of ouabain in dogs. | Experiments were undertaken to substantiate the hypothesis that the mechanism of the direct effect of ouabain on the renal excretion of electrolytes is the result of inhibition of the transport enzyme, (Na, K)-ATPase. In dogs hydrated with saline, an injection of 3H-ouabain into the unilateral renal artery produced a c... | 133,262 | [
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... |
[Paraiotonchium osiris (Iontonchiinae : Tylenchida), a new species of nematode of the zoophilic fly, Musca osiris Wd]. | The description and figures are given to the nematode Paraiotonchium osiris sp. n. parasitic in the body cavity of Musca osiris and in the genital organs of the host females from Turkmenia. Two morphologically different generations of nematodes, gamagenetic and parthenogenetic ones, develop in the body cavity of the in... | 133,319 | [
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... |
A defect in tryptophan metabolism. | Oral tryptophan loading tests were performed in a patient with photosensitive pellagra-like skin rash and cerebellar ataxia but without hyperaminoaciduria. Plasma tryptophan concentrations after loading were similar in the patient and control subjects. Average urinary excretion of tryptophan in the patient from 0 to 6 ... | 133,325 | [
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0.165512... |
Fetal lung lecithin metabolism in the glucose-intolerant Rhesus monkey pregnancy. | Fetal lung lecithin metabolism was examined in rhesus monkey gestations complicated by glucose intolerance secondary to maternal streptozotocin (STZ) administration. Fetuses of STZ-treated mothers were delivered at 85% to 89% of term and were compared to two control groups of fetuses from normal pregnancies--one group ... | 133,326 | [
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[Epidemiology of acute leukemia of childhood in Greece (author's transl)]. | A retrospective study of 151 aged less than 15 years children suffering from acute leukaemia is reported, the parameters studied were male: female ratio, type of leukemia, age and seasonal distribution of the illness. The disease started in spring in 53 children (35,1%), in summer in 34 (22,6%), in autumn in 36 (23,8%)... | 133,334 | [
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0.... |
[Homozygosity and atypical myeloproliferative syndrome (author's transl)]. | An abnormal clone with four chromosomal rearrangements was found in the bone marrow of a patient with an atypical myeloproliferative syndrome and with an almost exclusive polymorphonuclear hyperplasia in blood: t (4;12), i(17 q),20q--. An heterozygosity for a normal variant of one chromosome No. 3 was observed in blood... | 133,336 | [
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0.1937744,
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Preparation of enterochelin from Escherichia coli. | A convenient method has been developed for the preparation of enterochelin, the natural iron carrier produced by Escherichia coli. The method employs a mutant strain which is unable to transport the ferric-enterochelin complex into the cell and which excretes large quantities of enterochelin into the culture medium. Th... | 133,343 | [
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... |
Effect of 6-azauridine on calcium metabolism in rats. | After 12 days of intramuscular administration of 6-azauridine (500 mg/kg b.w.) rats displayed a significant decrease in plasma calcium, inorganic phosphorus, and total hydroxyproline levels and alkaline and acid phosphatase activity. The biological method employed revealed no changes in calcitonin activity. 6-Azauridin... | 133,364 | [
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0.1983824,
0.3996834,
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0... |
Reduction of alcohol selection by pargyline in mice. | Drugs which increase brain levels of serotonin (5-HT) have frequently been found to cause a decrease in voluntary ethanol consumption. Results obtained with parachlorophenylalanine (pCPA), which decreases 5-HT, have been less consistent. The present investigation compared the effects of pCPA on alcohol selection with t... | 133,369 | [
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0.06924707,
-... |
[Preservation of rat liver using prolonged perfusion with a complex solution lacking hemoglobin]. | The author's aim was to investigate conservation of rat liver by continuous perfusion of the isolated organ in conditions of normal temperature, as well as in hypothermia. A complex solution was used, lacking hemoglobin. Over a period of 5 hours of conservation the authors evaluated the perfusion rate, the concentratio... | 133,378 | [
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[The place of total nephro-ureterectomy in the treatment of urinary tuberculosis]. | Taking into consideration the frequency of urethral lesions in the frame of uro-genital tuberculosis, and their serious effects on the renal tissue it becomes apparent that either conservative or radical surgical therapies should be applied when their extension make it mandatory. Besides prevention of development, or o... | 133,397 | [
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0.3708348,
0.4704356,
-0.17254... |
[Orthopedic surgery in children with low intelligence quotients]. | 53 mentally retarded children (IQ lower than 50) sustained orthopaedic procedures for improving locomotion. In this series the authors operated on 26 feet, 6 knees, 22 hips, 8 spines. One only case was operated on the upper limb. Results are carefully analysed. Complete failures were noted in 9 cases. The importance of... | 133,419 | [
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0.04801466,
... |
[Distribution of subtypes of viral hepatitis B antigen in areas of Rumania]. | The results of subtyping the B antigen in 551 sera from patients with viral hepatitis, chronic evolutive hepatitis and cirrhosis, chronic carriers, donors and healthy subjects, were confirmed as positive HBAg by diffusion in agar, counterelectrophoresis and radioimmunology, and characterized by the d-y and w-r determin... | 133,442 | [
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0.5957644,
0.1318342,
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... |
[Study of purified aldolase from Saccharomyces cerevisiae, using irradiated fructose-1,6-diphosphate]. | The interaction of an electromagnetic field with the enzymatic substrate-- the sodium salt of fructose-1,6-disphosphate--induces in the latter a new type of physical transition S leads to S. The enzyme, in this case Saccharomyces cerevisiae aldolase, is able to reveal this new state of the substrate by an increase in i... | 133,446 | [
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-0.1744516,
... |
[Calculation of the chance of paternity exclusion for the HL-A system (author's transl)]. | Using a theoretical model formulas for the calculation of the chance of paternity exclusion for 2 closely linked autosomal loci with multiple allelism between which linkage disequilibrium exists are presented. With some examples their practicability for the HL-A system is shown. | 133,546 | [
0.03248749,
0.05592775,
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0.4177299,
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0.09263115,
0.1698971,
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0.0468962,
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0.4566062,
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... |
Atrial myxoma in a family. | A family is described in which the mother and three of seven children had atrial myxoma. The mother had biatrial myxoma; surgical treatment resulted in massive intraoperative embolization and death. Surgery was sucessful in two sons with left atrial myxoma and systemic arterial embolization. A third son had calcified r... | 133,607 | [
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0.1266709,
0.4148429,
0.1036939,
-0.1620756,
... |
Extrathoracic repair of branch occlusions of the aortic arch. | Thirty extrathoracic operations in twenty-six patients with occlusive disease involving the primary branches of the aortic arch were reviewed. Spanning a fourteen year experience, these operations included carotid-subclavian artery bypass, retrograde common carotid artery thrombectomy, carotid-carotid artery bypass, an... | 133,620 | [
0.04953882,
0.06816617,
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0.04013448,
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0.01098268,
0.349795,
0.349862,
0.02460353... |
Analgesic and anti-inflammatory activity of 6-chloro-alpha-methyl-carbazole-2-acetic acid (C-5720). | The carbazole, C-5720, has the same order of analgesic, antipyretic and anti-inflammatory activity as indomethacin and is more potent than phenylbutazone and acetylsalicylic acid in the yeast inflamed paw, the carrageenin foot edema, the Mycobacterium butyricum-induced pyrexia, and the acute and chronic adjuvant arthri... | 133,645 | [
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0.2824517,
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0.6915065,
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0.1433215,
-0.1830698,... |
Parachlorophenylalanine reversal of tranylcypromine effects in depressed patients. | Hospitalized bipolar and unipolar endogenously depressed patients who showed an antidepressant response to the monoamine oxidase (MAO) inhibitor, tranylcypromine sulfate, relapsed (ie, depression returned) when relatively small doses of parachlorophenylalanine (PCPA) were added for brief periods. Considered together wi... | 133,650 | [
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0.1049539,
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0.2930683,
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0.2101885,
-0.1698204... |
Acute immune complex disease associated with hepatitis. Etiopathogenic and immunopathologic studies of the renal lesion. | Immune deposit glomerulonephritis has been associated with hepatitis B antigenemia. Immune complexes of this antigen and its antibody have been implicated in the pathogenesis of the renal disease. A boy had acute immune complex disease with glomerulitis in which cryoprecipitable complexes of HbsAg and its antibody were... | 133,651 | [
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0.01516215,
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0.2132072,
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0.2135489,
0.05267234,
0.3885327,
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0.1712947,
0.09708927,
0.2797562,
-0.2010881,
-0.2301349,
... |
Control of rat mammary-gland pyruvate dehydrogenase by insulin and prolactin. | Withdrawal of prolactin or of insulin from the circulation of lactating rats leads, within 3h, to increased inactivation by phosphorylation of mammary-gland pyruvate dehydrogenase. Prolactin may act by priming the tissue to respond directly to normal concentrations of circulating insulin and by this means be responsibl... | 133,680 | [
0.003588815,
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0.009636311,
0.00507203,
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0.1782286,
0.04... |
Polycystic ovarian disease. | Sex hormone binding globulin (SHBG) capacity was reduced in 9 of 31 patients with polycystic ovarian (PCO) disease and the mean level in PCO patients was significantly less (p less than 0.001) than normal. Serum testosterone levels were elevated in 21 of 32 PCO patients and the mean level was significantly elevated (p ... | 133,709 | [
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0.1180255,
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0.1544702,
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0.04642173,
0.2500649,
0.2489332,
0.09299632,
0.3965417,
-0.5001918,
... |
Molecular weights and hydrophobicity of the polypeptide chain of sarcoplasmic reticulum calcium(II) adenosine triphosphatase and of its primary tryptic fragments. | The polypeptide chain of the Ca2+-stimulated adenosine triphosphatase from sarcoplasmic reticulum has a molecular weight of 119 000+/-6500 on the basis of sedimentation equilibrium measurements in sodium dodecyl sulfate. The two primary fragments obtained by limited proteolysis each have within experimental error the s... | 133,715 | [
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0.1618454,
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-0.1986793,
-0.2466394,
-0.02474211,
0.2999074,
0.06057416,
-0.1922864,
0... |
Steroid conjugates in human seminal plasma. | A technique for the measurement of five conjugated steroids (dehydroepiandrosterone sulphate, pregnenolone sulphate, testosterone sulphate, dihydrotestosterone sulphate and testosterone glucuronide) in human seminal plasma is described. The steroid sulphates and testosterone glucuronide were measured by radioimmunoassa... | 133,773 | [
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-0.1603185,
-0.1506576,
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0.05905551,
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0.0779957,
0.1109951,
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0.1711916,
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0.0916248,
0.4953264,
0.3628118,
-0.08028968,
... |
Situs inversus, subaortic and subpulmonic stenosis, ventricular septal defect, and single coronary artery. | The unusual occurrence of situs inversus totalis, ventricular septal defect, hypertrophic subaortic and subpulmonic stenosis, and single coronary artery in a 38-year-old man is presented. The clinical course was remarkably mild, as documented by data from 23 years of study including four cardiac catheterizations. At ag... | 133,789 | [
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0.2839383,
-0.006789779,
-0.1131302,
0.2407485,
0.3082407,
-0.2679713,
... |
The effect of p-chlorophenylalanine on the pethidine- or methadone-induced decrease in locomotor activity of rats. | Either pethidine HCl (50 mg/kg s.c.) or methadone HCl (8 mg/kg s.c.) produced a prominent decrease in locomotor activity of rats. Pretreatment of rats with p-chlorophenylalanine (p-CPA, 320 mg/kg i.p.) 48 h before the narcotic injection significantly antagonized the activity-decreasing effects of narcotics. When rats p... | 133,805 | [
-0.01956293,
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-0.3968209,
-0.03256056,
0.3045095,
0.06594606,
-0.4555301,
-0.2252486,
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0.06758578,
0.3598248,
0.2149307,
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-0.3874691,
-0.08360979,
0.2005698,
0.3389965,
-0.2172841,
0.0148432,
0.1151424,
... |
Interaction of genes and metals in development. | Examples are presented in interactions between genetic factors and certain trace during development in experimental animals. One type of interaction irenatal nutritional manipulation. The other involved strain differences, which lead differential responses to dietary deficiency. The mutant gene pallid in mice produces ... | 133,823 | [
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0.01925624,
-0.2608477,
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0.08440869,
0.4591408,
0.1213867,
0.002055348,
0.4641518,
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-0.06835323,
0.2458619,
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-0.2768817,
-0.245581,
0.2557202,
0.2299237,
0.4610091,
-0.1042267,... |
Effect of 1-methyl-1-nitrosourea and streptozotocin on glucose-induced insulin secretion by isolated islets of Langerhans. | The present experiments were designed to compare the effects of streptozotocin and 1-methyl-1-nitrosourea upon glucose-induced insulin secretion by isolated islets of Langerhans. Both drugs depressed the insulin response at one and two hours incubation but higher molar concentrations of the nitrosourea were required to... | 133,846 | [
-0.1396969,
-0.1172077,
-0.3155789,
-0.1685917,
0.009105976,
-0.2719669,
-0.2398859,
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0.03695934,
0.2068762,
0.04884852,
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0.08049826,
-0.06210339,
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-0.1871073,
0.2299998,
0.08936983,
0.2938605,
0.1133187,
0.05986356,
0.07904... |
[Inbreeding in the population and the spread of schizophrenia in one of the rural regions of Azerbaijan]. | The investigation was carried out in Pushkin region of Azerbaijan SSR. The coefficient of inbreeding was found to be 0,01306 and 0,01142 in 2 typical villages; the frequency of consanguineous marriage in both villages was 30%. The occurence of consanguineous marriage is explained by a little migration of the population... | 133,857 | [
0.307967,
-0.2946241,
0.2077317,
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0.1202506,
-0.2862038,
-0.5171925,
-0.2174892,
-0.03018574,
0.1813655,
0.1147479,
0.2760266,
0.04444027,
0.1615162,
-0.6229835,
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0.1774268,
0.1376247,
-0.04840668,
0.05179076,
0.2762164,
0.1118648,
-0.... |
[Clinico-genetic features of epilepsy in isolates and a panmictic population with intra-pair, intra-isolate and inter-isolate analysis]. | Clinico-genealogical investigation revealed certain specific clinico-genetic characteristics of epilepsy under the conditions of isolation (62 cases) as compared to a panmictic population (76 cases). Itra-pair inter-isolate (31 pairs) and intra-isolate (29pairs) comparison has shown a higher frequency of complete pheno... | 133,860 | [
0.04041645,
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0.01244307,
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0.2364912,
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0.08255292,
0.1244503,
0.3041031,
0.04342293,
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0.403697,
-0.1280898,... |
[Functional scintigraphic radiospirometry. First clinical results in patients with lung diseases]. | First clinical results of patients with diseases of the lungs. The previous experiences on patients with diseases of the lungs reveal that the regional function diagnostics of the lungs may be extended and improved by functional scintigraphic radiospirometry. Because of the determination of regional lung volumes restri... | 133,890 | [
0.09313545,
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0.1356178,
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0.1439515,
0.295506,
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-0.167979,
0.03690716,
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-0.2224049,
0.3605647,
0.04502587,
0.08554377,
0.08114941,
0.1058024,
0.09097081... |
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