title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
|---|---|---|---|
Endovascular aortoiliac aneurysm repair: surgical progress through new treatment paradigms and innovative endograft design. | Effective treatment for patients with an abdominal aortic aneurysm (AAA) began more than 50 years ago through the development of prosthetic grafts, which were used to replace aneurysmal segments of diseased arteries. Open surgical repair of AAAs became the gold standard for treating this disease. In 1999, two device ma... | 25,172,562 | [
-0.1110182,
-0.06416016,
-0.2722509,
-0.02092729,
0.07972011,
-0.02103694,
-0.05981003,
0.2153277,
0.2566013,
0.01522578,
0.252821,
-0.1123869,
-0.1755113,
-0.4010178,
-0.3375865,
-0.2226548,
-0.5216808,
0.1451584,
-0.1498448,
-0.1415784,
-0.1573224,
0.09893351,
-0.032551... |
Back to basics: positioning the patient. | Positioning the surgical patient requires special attention from the entire surgical team because anesthetized or sedated patients are not able to reposition themselves when needed to relieve discomfort or alert team members of the need for repositioning. Perioperative nurses must pay attention to positioning details a... | 25,172,564 | [
-0.120211,
0.2056396,
-0.2442626,
-0.2339721,
-0.1950201,
-0.3682922,
-0.1299915,
-0.3438283,
-0.03217401,
-0.01734699,
0.04106021,
-0.2979357,
-0.1482274,
-0.1343971,
-0.1538772,
0.02145746,
-0.8218613,
-0.1037642,
-0.04616254,
-0.05390446,
-0.3633795,
0.1784927,
0.16543... |
Temporal characterization of mercury accumulation at different trophic levels and implications for metal biomagnification along a coastal food web. | The main goal of this study was to assess temporal mercury variations along an estuarine food web to evaluate the mercury contamination level of the system and the risks that humans are exposed to, due to mercury biomagnification. The highest mercury concentrations in the sediments and primary producers (macrophytes) w... | 25,172,612 | [
-0.3360054,
-0.2776698,
0.1790515,
-0.1651409,
0.02302014,
-0.2225705,
-0.2613577,
0.07648066,
-0.1041143,
-0.04751883,
-0.1028032,
-0.3155823,
-0.2201578,
-0.2266812,
-0.3189288,
-0.03674963,
-0.4588039,
0.2066986,
0.3217466,
-0.04052765,
0.0693501,
0.4018117,
-0.2487299... |
Modulation of immune development and function by intestinal microbiota. | The immune system must constantly monitor the gastrointestinal tract for the presence of pathogens while tolerating trillions of commensal microbiota. It is clear that intestinal microbiota actively modulate the immune system to maintain a mutually beneficial relation, but the mechanisms that maintain homeostasis are n... | 25,172,617 | [
-0.1200021,
-0.1674098,
0.06065222,
-0.03980197,
0.1227814,
-0.2272992,
0.06706631,
0.2899376,
-0.004318805,
0.01534819,
-0.03376042,
-0.2316158,
-0.03834933,
0.1081019,
-0.6601722,
-0.237955,
-0.73586,
-0.1086696,
-0.1021239,
-0.01943299,
-0.08804849,
0.2832644,
-0.25253... |
Cerebellar mechanisms of learning and plasticity revealed by delay eyelid conditioning. | The analysis of well-defined behaviors that require the cerebellum has helped reveal many key mechanisms operating in the cerebellum to mediate learning and feed-forward prediction. These systems include eyelid conditioning, adaptation of the vestibuloocular reflex, smooth pursuit eye movements, and arm-reaching tasks.... | 25,172,627 | [
-0.03324717,
-0.07637168,
-0.4797342,
-0.4600248,
0.1813797,
-0.428826,
0.1209963,
-0.09012087,
0.1441284,
0.2050925,
0.00005041487,
0.3304339,
0.03956223,
-0.01586327,
-0.05728536,
-0.009467987,
-0.3607796,
0.1894399,
-0.308304,
0.0963423,
0.08005563,
-0.1251242,
0.02171... |
Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans. | Reduced plasma LDL-cholesterol is a hallmark of hyperthyroidism and is caused by transcriptional stimulation of LDL receptors in the liver. Here, we investigated whether thyroid hormone (TH) actions involve other mechanisms that may also account for the reduction in LDL-cholesterol, including effects on proprotein conv... | 25,172,631 | [
0.2079984,
-0.1234107,
-0.2470437,
-0.2502558,
-0.02446086,
-0.2224686,
-0.08083131,
0.04949102,
-0.03632967,
0.1362048,
0.1125512,
0.2288796,
0.1046657,
-0.2344889,
-0.1592615,
-0.2936369,
-0.2629747,
0.1021463,
-0.3868461,
0.4041143,
0.08321162,
-0.01593873,
-0.1671725,... |
Rabies control and elimination: a test case for One Health. | One Health approaches have already been shown to be successful in controlling rabies in different parts of the world. In this article, the latest in Veterinary Record's series promoting One Health, Sarah Cleaveland and her colleagues at the University of Glasgow discuss why integrated strategies are needed to enhance t... | 25,172,649 | [
-0.3606516,
0.06353398,
0.03540659,
-0.2385825,
-0.03797091,
-0.08449148,
-0.3467715,
-0.3953953,
0.03875889,
-0.1425948,
0.1668111,
0.09545616,
-0.07685147,
-0.07997351,
-0.3395111,
-0.04720756,
0.04629629,
0.04944222,
-0.0142261,
-0.2513094,
-0.2536666,
0.1745585,
0.030... |
Subcellular distribution and chemical forms of cadmium in the edible seaweed, Porphyra yezoensis. | The subcellular distribution and chemical forms of Cd were investigated in the edible seaweed, Porphyra yezoensis. The seaweed was exposed to different Cd concentrations (0.01, 0.05, 0.1, 0.5, 1.0 and 5.0mgl(-1)) for up to 96h. In both the controls (no Cd added) and treatment groups, 41.2-79.2% of Cd was localised in t... | 25,172,682 | [
0.04878951,
-0.3928472,
-0.06898244,
0.4048883,
0.08961642,
0.03618395,
-0.1445072,
0.5663378,
0.08018268,
0.162728,
0.02111265,
0.003957695,
-0.2158823,
-0.1281686,
0.04274261,
-0.2885878,
-0.2545424,
0.3427663,
0.1777343,
0.1112108,
0.4519737,
0.7565452,
-0.1719586,
-... |
Determination of advanced glycation endproducts in cooked meat products. | Advanced glycation endproducts (AGEs), a pathogenic factor implicated in diabetes and other chronic diseases, are produced in cooked meat products. The objective of this study was to determine the AGE content, as measured by Nε-carboxymethyllysine (CML) levels, in cooked chicken, pork, beef and fish (salmon and tilapia... | 25,172,699 | [
-0.31883,
0.07471978,
-0.1902483,
-0.1806166,
-0.05283909,
-0.02071701,
0.2527015,
0.3118818,
0.2943321,
0.08171281,
0.1633949,
0.1520693,
-0.03162489,
-0.3557992,
-0.2540274,
-0.2429282,
-0.3285339,
0.1702636,
0.3150633,
0.2491001,
0.01514607,
0.2256494,
-0.200237,
-0.... |
Flavonoids and phenolic acids from cranberry juice are bioavailable and bioactive in healthy older adults. | Cranberries (Vaccinium macrocarpon) are a rich source of phenolic phytochemicals, which likely contribute to their putative health benefits. A single-dose pharmacokinetic trial was conducted in 10 healthy adults ⩾50y to evaluate the acute (24-h) absorption and excretion of flavonoids, phenolic acids and proanthocyanidi... | 25,172,705 | [
0.08848623,
0.423725,
-0.1196867,
-0.1071374,
0.09586748,
-0.01800012,
-0.2795517,
0.1342034,
0.2350763,
-0.2784029,
0.07356425,
0.3043517,
0.04710219,
-0.3289021,
-0.208422,
-0.376272,
-0.6067769,
0.1514854,
0.5275702,
-0.07674515,
-0.1021274,
0.5042567,
-0.3049361,
-0... |
Comprehensive metabolomics to evaluate the impact of industrial processing on the phytochemical composition of vegetable purees. | The effects of conventional industrial processing steps on global phytochemical composition of broccoli, tomato and carrot purees were investigated by using a range of complementary targeted and untargeted metabolomics approaches including LC-PDA for vitamins, (1)H NMR for polar metabolites, accurate mass LC-QTOF MS fo... | 25,172,720 | [
0.05810321,
0.3470987,
-0.2323468,
0.2264187,
0.1504734,
-0.07485662,
0.1612616,
0.02633474,
-0.060224,
-0.128516,
0.3538272,
0.1448583,
-0.1937986,
-0.4702034,
-0.3910427,
0.2869654,
-0.7438446,
0.2004495,
0.4717191,
0.02336804,
0.272163,
0.4771243,
-0.4245705,
-0.0570... |
Rapid determination of pesticide residues in fruits and vegetables, using ultra-high-performance liquid chromatography/time-of-flight mass spectrometry. | A multiresidue method, based on the sample preparation by solid-phase extraction cartridges and detection by ultra-high-performance liquid chromatography/time-of-flight mass spectrometry (UHPLC/TOF-MS), was used for the analysis of 60 pesticides in vegetable and fruit samples. Quantitation by UHPLC/TOF-MS is accomplish... | 25,172,721 | [
-0.1315707,
0.0165775,
-0.1218759,
-0.4113501,
0.005675876,
-0.1456062,
-0.06984659,
0.09972836,
0.002168547,
-0.2964933,
0.334381,
0.3874946,
-0.005126824,
0.0431872,
-0.4036477,
-0.2106153,
-0.4485743,
0.5456071,
0.1562946,
0.01117596,
-0.0169608,
0.1717717,
-0.0410134,... |
Antioxidant activity and protective effect of extract of Celosia cristata L. flower on tert-butyl hydroperoxide-induced oxidative hepatotoxicity. | This study was undertaken to evaluate the antioxidant potential and protective effects of Celosia cristata L. (Family: Amaranthaceae) flower (CCF) extracts on tert-butyl-hydroperoxide (t-BHP)-induced oxidative damage in the hepatocytes of Chang cells and rat livers. In vitro, CCF extracts exhibited protective effect th... | 25,172,750 | [
-0.02490428,
-0.08107705,
-0.07393526,
0.1252301,
-0.06354707,
0.1243914,
-0.04921476,
-0.2018456,
0.08815546,
-0.3233624,
0.1907428,
0.2237357,
0.1127044,
0.2760047,
-0.4819034,
-0.02336744,
-0.4817129,
-0.03482025,
-0.01614049,
0.5098116,
-0.3161769,
0.1141072,
0.086374... |
Local mate competition and transmission bottlenecks: a new model for understanding malaria parasite and other sex ratios. | The local mate competition model from sex ratio theory predicts female-biased sex ratios in populations that are highly subdivided during mating, and is thought to accord well with the population structure of malaria parasites. However, the selective advantage of female-biased sex ratios comes from the resulting increa... | 25,172,770 | [
0.2011001,
-0.05307761,
-0.08243879,
-0.08377366,
0.01212607,
-0.247995,
-0.02525657,
-0.1321137,
0.127402,
-0.1821221,
-0.2287444,
0.1277138,
-0.06608766,
0.4793251,
-0.460119,
-0.3576383,
-0.3611579,
0.026855,
0.1786432,
0.05505593,
0.06842361,
0.2712443,
-0.04909091,
... |
[Immune thrombocytopenia and pregnancy: State of knowledge and unanswered questions]. | Pregnancy is a common problem in women with immune thrombocytopenia (ITP). It could be a source of anxiety for the patients and their family, nurses and medical doctors and many questions are unresolved in this setting. Most of published recommendations were based on experts' opinion rather than on evidence-based medic... | 25,172,779 | [
0.07632722,
0.04409054,
0.1262574,
-0.03384954,
0.2633753,
-0.3030041,
0.1137144,
-0.02818031,
-0.3292594,
-0.09936669,
0.1544896,
0.210522,
0.08312378,
-0.3619519,
-0.4553725,
-0.4779129,
-0.5294384,
0.2577445,
-0.07152545,
0.4657232,
0.2790157,
-0.06891891,
-0.0718879,
... |
Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies. | Garcinia mangostana is a well-known tropical plant found mostly in South East Asia. The present study investigated acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of G. mangostana extract and its chemical constituents using Ellman's colorimetric method. Cholinesterase inhibitory-guide... | 25,172,794 | [
-0.1256916,
0.2594362,
0.1037187,
-0.183447,
0.02783636,
0.04073542,
-0.2888072,
0.06847835,
0.2898915,
-0.3389179,
0.006210566,
0.2429364,
-0.0674407,
-0.4056351,
-0.6403691,
0.1800298,
-0.6119862,
0.5179826,
-0.01231538,
-0.05318365,
0.2192428,
0.2164257,
0.09672198,
... |
Environmental factors shape the community of symbionts in the hoopoe uropygial gland more than genetic factors. | Exploring processes of coevolution of microorganisms and their hosts is a new imperative for life sciences. If bacteria protect hosts against pathogens, mechanisms facilitating the intergenerational transmission of such bacteria will be strongly selected by evolution. By disentangling the diversity of bacterial strains... | 25,172,851 | [
0.2479525,
-0.1738099,
0.1617465,
0.03191875,
-0.2715317,
-0.4451128,
-0.03644698,
-0.269498,
0.2316021,
-0.1294592,
-0.05306552,
-0.1430639,
-0.06225586,
-0.2939932,
-0.6610762,
-0.08625919,
-0.3521622,
-0.1175583,
0.1456784,
0.06311987,
-0.07347734,
0.2961861,
-0.318160... |
Clinicohematologic Profile of Patients With Factor VIII Inhibitors: A Case Series. | Factor VIII (FVIII) inhibitors present major clinical challenge as a complication of hemophilia A in patients on treatment with FVIII concentrates and as acquired autoantibodies in patients without hemophilia A. We aimed to study the prevalence of FVIII inhibitors in Indian settings, risk factors involved in early deve... | 25,172,870 | [
0.005285854,
-0.01073191,
0.02504308,
-0.1560205,
0.09799934,
-0.2163242,
-0.2082988,
0.2342476,
-0.333422,
-0.2256337,
0.2038005,
0.3197855,
0.07394563,
-0.3682076,
0.1010973,
-0.126705,
-0.216612,
-0.02916737,
-0.09794603,
0.2016523,
0.1164188,
-0.02635426,
-0.225612,
... |
Reducing the risk of hypoglycemia associated with intravenous insulin: experience with a computerized insulin infusion program in 4 adult intensive care units. | Computerized insulin infusion protocols have facilitated more effective blood glucose (BG) control in intensive care units (ICUs). This is particularly important in light of the risks associated with hypoglycemia. End stage renal disease (ESRD) increases the risk of insulin-induced hypoglycemia. We evaluated BG control... | 25,172,875 | [
-0.02224233,
0.06744032,
-0.3213311,
-0.2268949,
0.2519496,
-0.02888986,
-0.0130653,
0.1397749,
-0.006841519,
-0.04978581,
0.08818321,
0.02379895,
-0.2405688,
-0.4005946,
0.1278652,
0.08664849,
-0.344454,
0.2192126,
0.1907927,
-0.09366251,
-0.3763149,
0.08347746,
0.235723... |
α1- and α2-adrenergic responsiveness in human skeletal muscle feed arteries: the role of TRPV ion channels in heat-induced sympatholysis. | The purpose of this study was to determine if heat inhibits α2-adrenergic vasocontraction, similarly to α1-adrenergic contraction, in isolated human skeletal muscle feed arteries (SMFA) and elucidate the role of the temperature-sensitive vanilloid-type transient receptor potential (TRPV) ion channels in this response. ... | 25,172,894 | [
0.2068915,
-0.2387374,
-0.07402059,
-0.3155624,
-0.1558896,
-0.2944153,
-0.3955798,
-0.06411994,
0.1610493,
-0.2015118,
0.3707182,
-0.0487557,
0.1356674,
-0.5762486,
-0.5207124,
-0.2429919,
-0.9083102,
0.1165935,
0.1645386,
-0.01723395,
0.1963198,
0.3792615,
-0.2928002,
... |
Heme oxygenase-1 attenuates acute pulmonary inflammation by decreasing the release of segmented neutrophils from the bone marrow. | Recruiting polymorphonuclear neutrophil granulocytes (PMNs) from circulation and bone marrow to the site of inflammation is one of the pivotal mechanisms of the innate immune system. During inflammation, the enzyme heme oxygenase 1 (HO-1) has been shown to reduce PMN migration. Although these effects have been describe... | 25,172,914 | [
-0.08715162,
0.05352427,
-0.4839324,
-0.127428,
-0.09069943,
-0.304746,
0.1239723,
-0.1203606,
-0.2480228,
0.0766737,
-0.1380835,
-0.4109807,
-0.1911632,
-0.03508051,
-0.1411414,
-0.04251438,
-0.3871078,
0.07210503,
0.0723227,
0.2354604,
-0.02703672,
0.02639963,
-0.072570... |
Frameshift alignment: statistics and post-genomic applications. | The alignment of DNA sequences to proteins, allowing for frameshifts, is a classic method in sequence analysis. It can help identify pseudogenes (which accumulate mutations), analyze raw DNA and RNA sequence data (which may have frameshift sequencing errors), investigate ribosomal frameshifts, etc. Often, however, only... | 25,172,925 | [
0.009832752,
0.0383624,
-0.2009774,
-0.02657599,
0.1396673,
-0.0681503,
-0.1245592,
0.0331441,
0.2245367,
-0.3143197,
0.07944915,
-0.1393579,
0.1118448,
-0.08386295,
-0.346508,
-0.08465265,
-0.0581582,
-0.03961417,
0.0341042,
-0.32842,
0.03395262,
0.2669858,
-0.05592901,
... |
Isolation of Campylobacter from Brazilian broiler flocks using different culturing procedures. | Conventional culturing methods enable the detection of Campylobacter in broiler flocks. However, laboratory culture of Campylobacter is laborious because of its fastidious behavior and the presence of competing nontarget bacteria. This study evaluated different protocols to isolate Campylobacter from broiler litter, fe... | 25,172,927 | [
-0.04449363,
0.2322766,
0.1243911,
-0.02671426,
0.2210464,
-0.01166486,
-0.4012581,
0.1720672,
-0.1698906,
-0.2787682,
0.1491871,
0.4010907,
0.1109026,
0.2272178,
-0.1994811,
0.02688213,
-0.7680536,
-0.4137597,
-0.05438294,
0.07517751,
0.3458418,
-0.1927505,
-0.02962637,
... |
Aberrant T cell expression of Ca2+ influx-regulated miRNAs in patients with systemic lupus erythematosus promotes lupus pathogenesis. | The aim of this study was to investigate the pathogenic role of calcium (Ca(2+)) influx-regulated microRNAs (miRNAs) in T cells from patients with SLE. Expression profiles of 270 human miRNAs in Jurkat cells co-cultured with or without ionomycin were analysed by real-time PCR. Differential expression of miRNAs in T cel... | 25,172,935 | [
-0.300435,
-0.1866996,
-0.5455718,
0.1227172,
-0.02034996,
-0.1306377,
-0.4606806,
0.2547921,
0.04174208,
0.1519953,
-0.08653486,
0.5002183,
-0.3572916,
0.05689295,
-0.3823514,
0.1876086,
0.1882833,
0.05866294,
-0.2857575,
0.2101389,
0.4742951,
0.6257201,
-0.2190427,
0.... |
Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans. | The pancreatic islets are central to the maintenance of glucose homeostasis through insulin secretion. Glucose‐stimulated insulin secretion is tightly linked to electrical activity in β cells within the islet. Gap junctions, composed of connexin36 (Cx36), form intercellular channels between β cells, synchronizing elect... | 25,172,942 | [
-0.01652676,
-0.4070465,
-0.5138283,
-0.03887866,
0.211264,
-0.2318561,
0.2411579,
0.3445553,
0.3438959,
-0.1646906,
0.1603208,
-0.2873672,
-0.3321036,
-0.004126217,
-0.253208,
-0.1092647,
-0.5336149,
0.2480902,
0.0763863,
-0.2096863,
-0.003380429,
-0.06386158,
0.1261373,... |
Voltage- and ATP-dependent structural rearrangements of the P2X2 receptor associated with the gating of the pore. | P2X2 is an extracellular ATP-gated cation channel which has a voltage-dependent gating property even though it lacks a canonical voltage sensor. It is a trimer in which each subunit has two transmembrane helices and a large extracellular domain. The three inter-subunit ATP binding sites are linked to the pore forming t... | 25,172,943 | [
0.01997619,
0.007629815,
-0.3189558,
-0.05456275,
0.1708216,
-0.2726711,
0.1336073,
0.1921826,
0.2333652,
0.1561002,
-0.2559622,
0.1521328,
-0.1962765,
-0.2438993,
-0.4332595,
-0.2451731,
-0.6772074,
-0.1567348,
-0.2434867,
0.09112496,
0.2402593,
0.5529162,
-0.2048862,
... |
Rapid mapping of visual receptive fields by filtered back projection: application to multi-neuronal electrophysiology and imaging. | Neurons in the visual system vary widely in the spatiotemporal properties of their receptive fields (RFs), and understanding these variations is key to elucidating how visual information is processed. We present a new approach for mapping RFs based on the filtered back projection (FBP), an algorithm used for tomographi... | 25,172,952 | [
0.04341115,
-0.04749668,
-0.5414223,
0.02598134,
-0.1074302,
-0.486638,
0.0310983,
0.230794,
0.02646045,
-0.1277543,
0.1067671,
-0.1069725,
0.005005419,
0.1443333,
-0.3596173,
-0.2728997,
-0.4547856,
0.1277983,
0.1559584,
0.1577223,
0.338587,
0.3795178,
-0.03312901,
0.0... |
Diethylpyrocarbonate modification reveals HisB5 as an important modulator of insulin amyloid formation. | More than 30 amyloid proteins are reported to be associated with amyloidosis diseases. Studies have implicated histidine may be critically involved in amyloid formation. Here, we used diethylpyrocarbonate (DEPC) modification to obtain a His(B5) mono-ethyloxyformylated insulin (DMI-B(5)). The secondary structure, amyloi... | 25,172,962 | [
-0.1032442,
0.1263794,
0.1367837,
0.09265576,
-0.1589994,
0.02184492,
0.2597448,
0.4509882,
0.103717,
0.3847684,
-0.06196204,
0.0513766,
-0.2855467,
-0.0966824,
0.07287808,
-0.142066,
-0.2829058,
0.09760892,
-0.1749379,
0.0127774,
0.06631254,
0.493696,
0.2332477,
-0.268... |
Colloid cysts of the third ventricle exhibit various clinical presentation: a review of three cases. | Colloid cysts are benign intracranial tumours usually occurring in the front part of the third ventricle. Clinical presentation may be non-specific and heterogeneous. The problems are frequently associated with development of hydrocephalus, these cysts may cause. We describe three cases of patients with diverse clinica... | 25,172,970 | [
-0.5074769,
0.2129315,
-0.07015989,
-0.4170321,
0.09977186,
-0.4133761,
-0.4056833,
-0.2863168,
0.2516806,
0.1058599,
0.1841526,
0.4080308,
-0.3581037,
-0.1703496,
-0.2599019,
-0.3208358,
-0.08652227,
-0.03549435,
-0.1178807,
-0.2447698,
-0.1225096,
0.02095288,
-0.1579243... |
Frequency of CCR5Δ32 allele in healthy Bosniak population. | Recent evidence has demonstrated the role of CCR5Δ32 in a variety of human diseases: from infectious and inflammatory diseases to cancer. Several studies have confirmed that genetic variants in chemokine receptor CCR5 gene are correlated with susceptibility and resistance to HIV infection. A 32-nucleotide deletion with... | 25,172,974 | [
0.1027745,
-0.3263408,
-0.2554426,
-0.05906027,
-0.0989277,
-0.07137612,
0.03508179,
-0.2386719,
0.02865377,
0.09155212,
0.07958001,
-0.20336,
0.1572924,
-0.06043091,
-0.59381,
-0.5669838,
-0.3583713,
-0.06985135,
0.2739034,
-0.02468214,
0.2966422,
0.2124247,
-0.04892401,... |
Beta lactam antibiotics residues in cow's milk: comparison of efficacy of three screening tests used in Bosnia and Herzegovina. | Beta lactam antibiotics are widely used in therapy of cattle, particularly for the treatment of mastitis. Over 95% of residue testing in dairies in Bosnia and Herzegovina is for Beta lactams. The aim of this paper is to compare the efficacy of three most common screening tests for Beta lactam residues in cow's milk in... | 25,172,975 | [
0.2990649,
-0.1728189,
0.008253081,
0.2859392,
-0.04820165,
0.01135281,
-0.1939295,
-0.120846,
0.3138488,
-0.1622399,
-0.00161867,
0.2089391,
0.3325563,
0.1517596,
-0.5568509,
-0.3226534,
-0.1701089,
0.03880149,
-0.1566053,
-0.1839679,
0.3177727,
0.1751729,
0.268082,
0.... |
Left ventricular mechanics in Behcet's disease: a speckle tracking echocardiographic study. | Although cardiac involvement is rarely seen in Behcet's disease (BD), it is essential to detect subclinical left ventricular (LV) dysfunction for prognostic purposes. Herein we aimed to show the role of two dimensional (2D) speckle tracking echocardiography (STE) in determination of subclinical LV dysfunction in patien... | 25,172,976 | [
0.01522211,
0.218105,
0.1601678,
-0.1804776,
-0.160317,
-0.4737745,
0.2804146,
0.2164184,
-0.2258833,
0.04132163,
-0.3503675,
-0.2033864,
-0.1553851,
0.2853514,
-0.2257733,
-0.1485542,
-0.1061032,
0.07251312,
-0.1196636,
-0.01149811,
0.5110741,
0.4938958,
-0.1356959,
0.... |
Raman spectroscopy in the diagnosis of ulcerative colitis. | At present, the diagnosis of ulcerative colitis (UC) requires the histologic demonstration of characteristic mucosal inflammatory changes. A rapid and noninvasive diagnosis would be of value, especially if it could be adapted to a simple rectal probe. Raman spectroscopy creates a molecular fingerprint of substances by ... | 25,172,984 | [
-0.03277209,
0.1768508,
-0.290797,
-0.2419424,
0.1931745,
-0.0283145,
-0.1341316,
0.1040339,
0.919311,
0.1129818,
0.08930617,
-0.1247722,
0.1225073,
-0.2716498,
-0.2269607,
0.06000309,
-0.4613695,
-0.02293836,
-0.06613813,
-0.189334,
0.04290267,
0.1369353,
-0.3200943,
0... |
Synthesis, DNA interaction and anticancer activity of copper(II) complexes with 4'-phenyl-2,2':6',2″-terpyridine derivatives. | Three novel copper(II) complexes CuL(1)Cl2 (1) (L(1)=4'-(3-methoxyphenyl)-2,2':6'- 2″-terpyridine), CuL(2)Cl2 (2) (L(2)=4'-(4-methoxyphenyl)-2,2':6'-2″-terpyridine) and CuL(3)Cl2 (3) (L(3)=4'-(3,5-dimethoxyphenyl)-2,2':6'-2″-terpyridine) have been synthesized and characterized. Absorption spectral titration experiments... | 25,172,994 | [
-0.2264517,
0.01447487,
0.03273318,
0.1473353,
0.1151112,
0.0901394,
-0.1447338,
0.01714597,
0.3791924,
0.3456944,
-0.03668628,
0.4180629,
-0.1378044,
0.1553186,
-0.9179818,
0.01500913,
-0.7778128,
0.2318009,
0.1925445,
0.591519,
0.5684932,
0.2393144,
0.08483015,
0.0589... |
Average local ionization energy generalized to correlated wavefunctions. | The average local ionization energy function introduced by Politzer and co-workers [Can. J. Chem. 68, 1440 (1990)] as a descriptor of chemical reactivity has a limited utility because it is defined only for one-determinantal self-consistent-field methods such as the Hartree-Fock theory and the Kohn-Sham density-functio... | 25,173,005 | [
-0.06054457,
0.2392413,
-0.06044497,
0.2005728,
0.07960524,
-0.2234101,
-0.2527444,
-0.01634476,
0.1453123,
-0.08129831,
-0.1195049,
-0.06299052,
0.2122013,
0.1556482,
-0.4514919,
-0.2869628,
-0.4217127,
0.1035048,
0.3265482,
0.1752558,
-0.08776188,
0.01317271,
-0.2376554... |
Dielectric constant and low-frequency infrared spectra for liquid water and ice Ih within the E3B model. | Two intrinsic difficulties in modeling condensed-phase water with conventional rigid non-polarizable water models are: reproducing the static dielectric constants for liquid water and ice Ih, and generating the peak at about 200 cm(-1) in the low-frequency infrared spectrum for liquid water. The primary physical reason... | 25,173,022 | [
-0.254226,
0.04235844,
0.06990594,
-0.2677747,
-0.07542568,
-0.1199792,
-0.1120105,
-0.1055253,
0.2087021,
0.1121401,
-0.1756957,
0.1975171,
-0.2212183,
0.008482319,
-0.2125017,
0.03428426,
-0.7450557,
0.2224078,
-0.2834211,
0.09007554,
-0.05650667,
0.1182346,
-0.1235414,... |
In utero and peripubertal exposure to phthalates and BPA in relation to female sexual maturation. | The age of pubertal onset for girls has declined over past decades. Research suggests that endocrine disrupting chemicals (EDCs) may play a role but exposure at multiple stages of development has not been considered. We examined in utero and peripubertal exposure to bisphenol-A (BPA) and phthalates in relation to serum... | 25,173,057 | [
-0.2292246,
-0.04277124,
-0.1325714,
-0.2408525,
-0.2029371,
-0.3155983,
-0.4400034,
0.3474281,
-0.04653274,
0.1514061,
0.09344338,
0.03302456,
-0.09029724,
-0.1762217,
-0.2255895,
-0.07633922,
-0.07075702,
-0.0921729,
0.2158794,
-0.294506,
0.08922172,
0.12748,
-0.251039,... |
Modeling of eating style and its effect on intake. | Observational research has indicated that modeling of eating style might occur when eating in the presence of an eating companion. This experiment investigated the effect of bite frequency of a same-sex eating companion on bite frequency, meal size and meal duration. A total of 30 normal weight young adults (m/f = 8/22... | 25,173,066 | [
-0.008013142,
0.5265756,
-0.4800751,
0.02538685,
0.1068896,
-0.302215,
-0.04401146,
-0.1061982,
-0.07668852,
-0.3281966,
0.1429517,
0.2807438,
0.08830645,
-0.4460578,
-0.8103535,
-0.04752436,
-0.2582277,
0.2443888,
0.04833201,
-0.2301307,
-0.0412356,
0.2166505,
-0.3231404... |
Early inflammatory cytokine response: a direct comparison between spontaneous coronary plaque destabilization vs angioplasty induced. | To compare inflammatory response accompanying acute coronary syndrome (ACS) with that following coronary plaque rupture caused by coronary angioplasty (PCI). Twenty-seven consecutive subjects with either ACS or treated with PCI in the subacute phase of ACS underwent serial evaluation of circulating interleukin (IL)-2, ... | 25,173,071 | [
-0.1305773,
0.2195166,
-0.4252696,
-0.3539994,
0.3636311,
-0.4049675,
-0.1533552,
0.03168936,
0.2145348,
-0.00928806,
-0.01889275,
0.09846345,
-0.1607215,
-0.1769014,
-0.1435221,
-0.3791037,
0.06544317,
-0.05370369,
0.08784647,
0.3342851,
0.1603881,
-0.07960354,
-0.208218... |
Metapragmatic explicitation ability in children with typical language development: development and validation of a novel clinical assessment. | Speech-language practitioners recognise the importance of metapragmatic (MP) ability (the ability to explicitly reflect on pragmatic rules) in therapy for children with pragmatic and social communication difficulties. There is inconclusive evidence in the literature regarding both the development of metapragmatic abili... | 25,173,072 | [
-0.3496611,
0.1136516,
-0.09565401,
-0.1936978,
0.203798,
-0.2534968,
-0.4468185,
0.003645409,
0.2266158,
-0.08544268,
-0.01211281,
0.1664004,
-0.2756589,
-0.1575874,
-0.03497397,
0.04786052,
-0.2994935,
0.09049704,
-0.4831647,
0.01476878,
0.3134005,
0.1830635,
-0.2110448... |
Cell migration is another player of the minute virus of mice infection. | The parvovirus minute virus of mice, prototype strain (MVMp), preferentially infects and kills cancer cells. This intrinsic MVMp oncotropism may depend in part on the early stages of MVMp infection. To test this hypothesis, we investigated the early events of MVMp infection in mouse LA9 fibroblasts and a highly invasiv... | 25,173,091 | [
-0.6289707,
-0.1028176,
-0.3597159,
-0.2436628,
0.0390518,
-0.3065326,
0.04267169,
0.3181327,
0.004054902,
0.3045963,
-0.1663032,
0.01907933,
0.03823122,
-0.433211,
-0.1925251,
-0.1311342,
-0.00808032,
-0.09683161,
0.09040374,
0.1232254,
0.3139633,
-0.07161137,
-0.0399948... |
Medical management of high-grade astrocytoma: current and emerging therapies. | High-grade astrocytomas are aggressive and incurable primary brain tumors. Radiation therapy with concurrent and adjuvant temozolomide chemotherapy is the standard-of-care treatment for newly diagnosed glioblastoma, while the role of chemotherapy in the initial treatment of anaplastic astrocytoma is evolving. Currently... | 25,173,143 | [
-0.3617492,
0.2712535,
0.105382,
-0.4786188,
0.06727686,
-0.271206,
-0.2209351,
-0.0705804,
-0.1339907,
0.1936379,
0.04187106,
0.1668859,
-0.1166757,
-0.1953165,
-0.17973,
-0.04801745,
-0.1190301,
0.3341464,
-0.01627226,
0.1821934,
-0.08823142,
0.158017,
-0.008891315,
0... |
Neural stem cell transplantation in an animal model of traumatic brain injury. | The central nervous system (CNS) can be damaged by a wide range of conditions resulting in loss of specific populations of neurons and/or glial cells and in the development of defined psychiatric or neurological symptoms of varying severity. As the CNS has limited inherent capacity to regenerate lost tissue and self-re... | 25,173,157 | [
-0.1099148,
-0.1505303,
-0.1485218,
-0.51229,
0.04166296,
-0.1653666,
-0.4598688,
-0.04678667,
0.2194912,
0.1831138,
-0.1009465,
-0.007945272,
0.1261046,
0.1715381,
-0.4567308,
-0.05413898,
-0.2696284,
-0.2071952,
-0.2052662,
0.3451019,
-0.1550824,
0.344976,
0.1861455,
... |
Preterm birth risk at high altitude in Peru. | High altitude has been implicated in a variety of adverse pregnancy outcomes including preeclampsia and stillbirth. Smaller studies show conflicting data on the association between high altitude and preterm birth (PTB). The objective of this study was to assess the association between altitude and PTB. A retrospective ... | 25,173,185 | [
0.2171813,
-0.09715562,
0.02785935,
0.3132592,
0.03639835,
-0.1462731,
-0.1835403,
-0.2556626,
0.1518473,
-0.1002164,
-0.1202982,
0.1141633,
-0.23075,
-0.24764,
-0.06318529,
-0.3494904,
-0.2815902,
0.1007338,
0.02327729,
-0.2148158,
-0.02359192,
0.2645863,
-0.06387424,
... |
The future of obstetrics/gynecology in 2020: a clearer vision: finding true north and the forces of change. | The pressure to transform health care has been building for many years, and many frameworks have been proposed for this transformation. The 'Triple Aim' concept of improving the health of the population, improving the experience of the patient, and controlling cost can be used as a guide post for the adoption of the ne... | 25,173,186 | [
-0.071326,
0.1126317,
-0.2824974,
-0.03552372,
0.00708073,
-0.2242755,
0.0732784,
0.1440503,
0.2831667,
0.2046684,
-0.2331912,
-0.226512,
-0.2624589,
-0.1331757,
-0.3572611,
-0.1732493,
-0.009369471,
-0.06765768,
-0.2868464,
-0.3211335,
-0.1538243,
0.2530731,
-0.2005642,
... |
Maternal morbidity in patients with morbidly adherent placenta treated with and without a standardized multidisciplinary approach. | The purpose of this study was to test the hypothesis that a standardized multidisciplinary treatment approach in patients with morbidly adherent placenta, which includes accreta, increta, and percreta, is associated with less maternal morbidity than when such an approach is not used (nonmultidisciplinary approach). A r... | 25,173,187 | [
-0.04691333,
-0.03189455,
-0.2570001,
-0.0817173,
0.1115187,
-0.6037127,
-0.2659018,
0.05969383,
0.1721145,
0.3454842,
-0.067545,
0.1025235,
-0.1523735,
-0.2693594,
-0.2831196,
0.06035741,
-0.1714354,
0.01301128,
-0.07186069,
-0.3115811,
0.1783332,
0.05363221,
-0.03736611... |
Nine additional complete genome sequences of HCV genotype 6 from Vietnam including new subtypes 6xb and 6xc. | We completely sequenced nine HCV-6 variants from Vietnam. They are grouped into six lineages beyond the 24 assigned subtypes, 6a-6xa, and 14 unclassified lineages that have been recently described with full-length genomes. Co-analysis with reference sequences in the NS5B region identified additional 22 such lineages, w... | 25,173,194 | [
-0.1303036,
0.343644,
-0.0002670941,
-0.003226225,
0.05936569,
-0.005134228,
-0.01881055,
0.06414658,
-0.006818524,
-0.347648,
-0.06615746,
-0.2844894,
-0.08707026,
-0.0494811,
-0.4234746,
-0.2150541,
0.05267866,
0.2884978,
0.190505,
-0.3289804,
0.05779922,
0.07789376,
-0... |
The effect of carbon black reinforcement on the dynamic fatigue and creep of polyisobutylene-based biomaterials. | This paper investigates the structure-property relationship of a new generation of poly(styrene-b-isobutylene-b-styrene) (SIBS) block copolymers with a branched (dendritic) polyisobutylene core with poly(isobutylene-b-para-methylstyrene) end blocks (D_IBS), and their carbon black (CB) composites. These materials displa... | 25,173,236 | [
-0.04300136,
0.4140405,
0.2354945,
0.0001871211,
-0.04882363,
-0.1426585,
0.1327987,
0.162111,
0.01271447,
0.5116019,
-0.03556019,
-0.2740861,
-0.1362817,
0.2022105,
-0.5725121,
-0.1281503,
-0.6448112,
-0.03020041,
0.05967582,
0.5943107,
0.002806703,
0.5233318,
-0.1352939... |
Alkali vapor pressure modulation on the 100 ms scale in a single-cell vacuum system for cold atom experiments. | We describe and characterize a device for alkali vapor pressure modulation on the 100 ms timescale in a single-cell cold atom experiment. Its mechanism is based on optimized heat conduction between a current-modulated alkali dispenser and a heat sink at room temperature. We have studied both the short-term behavior dur... | 25,173,251 | [
0.0114173,
-0.05452419,
-0.09543999,
0.1280056,
-0.06472604,
-0.09809259,
-0.3174166,
0.04369854,
0.1677841,
-0.1716311,
-0.03044021,
0.008404391,
-0.09014969,
-0.1087888,
-0.4961489,
-0.226089,
0.04517998,
-0.05186019,
0.07914398,
0.2658849,
0.2037024,
-0.001518502,
-0.2... |
Apparatus for the measurement of the speed of sound of ammonia up to high temperatures and pressures. | An apparatus for the measurement of the speed of sound based on the pulse-echo technique is presented. It operates up to a temperature of 480 K and a pressure of 125 MPa. After referencing and validating the apparatus with water, it is applied to liquid ammonia between 230 and 410 K up to a pressure of 124 MPa. Speed o... | 25,173,297 | [
-0.1522807,
0.04598368,
-0.206661,
-0.001042014,
0.01440015,
-0.1831204,
-0.2641404,
-0.0560706,
0.2584469,
-0.2721888,
-0.05097517,
-0.07980406,
0.2496257,
0.08556564,
-0.3872199,
-0.3102881,
-0.2098931,
0.01489832,
-0.4113316,
0.1306655,
0.224893,
-0.2736458,
-0.0841731... |
Three-dimensional printing of scintillating materials. | We demonstrate, for the first time, the applicability of three-dimensional printing techniques to the manufacture of scintillation detectors. We report on the development of a formulation, usable in stereolithographic printing, that exhibits scintillation efficiency on the order of 30% of that of commercial polystyrene... | 25,173,307 | [
-0.2499413,
0.3311699,
-0.07762802,
-0.01537011,
0.01353079,
-0.0374542,
-0.3686568,
0.08682916,
0.3145326,
-0.148421,
0.1114528,
-0.08072117,
-0.1473675,
-0.09378787,
-0.5551112,
-0.03853365,
-0.1187536,
0.02956654,
-0.1266649,
0.1416587,
0.3843443,
0.1966254,
-0.1752302... |
Deformation T-Cup: a new multi-anvil apparatus for controlled strain-rate deformation experiments at pressures above 18 GPa. | A new multi-anvil deformation apparatus, based on the widely used 6-8 split-cylinder, geometry, has been developed which is capable of deformation experiments at pressures in excess of 18 GPa at room temperature. In 6-8 (Kawai-type) devices eight cubic anvils are used to compress the sample assembly. In our new apparat... | 25,173,308 | [
-0.056072,
0.04395843,
0.004024104,
-0.03462929,
0.003437765,
-0.1183622,
-0.1258983,
0.103581,
0.1398654,
-0.04480363,
-0.1612487,
-0.1739335,
-0.06874882,
0.04782495,
-0.7858973,
-0.08600275,
-0.1457337,
-0.08584311,
-0.447159,
0.03935434,
0.2625155,
-0.1589106,
-0.3531... |
Undulator beamline of the Brockhouse sector at the Canadian Light Source. | The Brockhouse project at the Canadian Light Source plans the construction of three beamlines, two wiggler beamlines, and one undulator beamline, that will be dedicated to x-ray diffraction and scattering. In this work, we will describe the undulator beamline main components and performance parameters, obtained from ra... | 25,173,309 | [
0.09464063,
0.2536834,
0.1237829,
-0.2454696,
0.04451121,
-0.4939473,
-0.281411,
-0.02057283,
0.1055724,
0.02156336,
-0.1226867,
-0.2229213,
0.08267429,
-0.06597388,
-0.3544227,
-0.1515243,
-0.3491817,
-0.2268708,
-0.009217664,
-0.1903026,
0.157299,
-0.08007423,
-0.096886... |
Management of Strongyloides stercoralis: a puzzling parasite. | Strongyloides stercoralis is one of the common parasites in tropical areas. It can result in severe clinical syndromes, hyperinfection syndrome or disseminated strongyloidiasis in immunocompromised patients. The treatment of strongyloidiasis is a challenge for clinicians in clinical practice. Failure of treatment is du... | 25,173,343 | [
0.1554126,
0.109323,
0.4024925,
-0.2573315,
0.2006508,
-0.06927894,
-0.3266336,
0.1072124,
-0.1119841,
-0.1776435,
0.006372876,
-0.1068265,
-0.1275185,
0.3736548,
-0.3732038,
-0.1468215,
-0.386658,
-0.1776341,
-0.4011972,
0.2184666,
-0.0354728,
0.3667135,
0.06630871,
0.... |
Smoking did not modify the effects of anti-TNF treatment on health-related quality of life among Australian ankylosing spondylitis patients. | The aim of this study was to examine the impact of smoking on health-related quality of life (HRQoL) among AS patients who were taking biologic DMARDS. This is a longitudinal cohort study of AS patients with anti-TNF treatment in the Australian Rheumatology Association Database (2003-11). They were assessed using the 3... | 25,173,348 | [
0.03070633,
0.239596,
-0.268018,
0.3723477,
-0.1955408,
-0.3479543,
-0.09752168,
0.271777,
-0.2510522,
-0.4677874,
0.100262,
-0.0203488,
0.172887,
-0.3807248,
0.1125206,
0.01647083,
-0.04625319,
0.2223646,
0.1124573,
0.05552775,
-0.1681238,
-0.01875644,
-0.2795311,
0.04... |
Diagnosis and management of postoperative pancreatic fistula. | Postoperative pancreatic fistula (POPF) is the leading complication after partial pancreatic resection and is associated with increased length of hospital stay and resource utilization. The introduction of a common definition in 2005 by the International Study Group of Pancreatic Surgery (ISGPS), which has been since e... | 25,173,359 | [
0.1276883,
-0.2454685,
-0.1269525,
-0.1210919,
-0.07260288,
-0.298701,
0.3158809,
-0.0546734,
0.1369084,
0.25248,
-0.04659018,
-0.5225641,
-0.3134769,
-0.1038198,
-0.183953,
-0.4754275,
-0.1007686,
0.1047856,
0.2269757,
-0.1704981,
-0.3405879,
0.2225412,
-0.1109327,
-0.... |
Support of hepatic regeneration by trophic factors from liver-derived mesenchymal stromal/stem cells. | Mesenchymal stromal/stem cells (MSCs) have multilineage differentiation potential and as such are known to promote regeneration in response to tissue injury. However, accumulating evidence indicates that the regenerative capacity of MSCs is not via transdifferentiation but mediated by their production of trophic and ot... | 25,173,377 | [
-0.2326477,
-0.1729808,
-0.1732875,
-0.3350299,
0.1204556,
-0.1558195,
-0.102144,
0.1110501,
0.1013054,
0.1922411,
-0.04426893,
-0.1698079,
-0.03567183,
-0.2238427,
-0.4143552,
-0.1079435,
-0.06765566,
-0.08223536,
-0.181392,
0.3319838,
-0.09165812,
0.05491255,
-0.0107708... |
Angiogenic properties of mesenchymal stem cells in a mouse model of limb ischemia. | Mesenchymal stem cells (MSCs) can be obtained from adult bone marrow and adipose tissue in large quantities and are the main cell types that contribute to recovery from ischemia because, among their biological activities, they produce several proangiogenic paracrine factors and differentiate into endothelial cells. Mou... | 25,173,381 | [
-0.1612574,
-0.0466401,
-0.2201325,
-0.3151721,
0.1214705,
-0.1075876,
-0.01889932,
0.2296708,
0.1445269,
0.02653623,
-0.07150953,
-0.0203761,
-0.2361435,
-0.3748182,
-0.4778418,
-0.07112892,
-0.08644103,
-0.001064741,
-0.1583309,
0.4964995,
0.04776173,
-0.03242958,
-0.05... |
Methods to assess intestinal stem cell activity in response to microbes in Drosophila melanogaster. | Drosophila melanogaster presents itself as a powerful model for studying the somatic stem cells of the gut and how bacteria affect intestinal homeostasis. The Gal4/UAS/Gal80 (ts) system allows for temporally controlled expression of fluorescent proteins, RNAi knock-down, and other genetic constructs targeted to specifi... | 25,173,382 | [
0.5311183,
-0.4688791,
-0.006701639,
0.02344837,
0.3963432,
0.02443693,
0.2187264,
-0.08745643,
0.1664118,
0.05014903,
0.1454238,
0.1158496,
-0.1188507,
-0.1395801,
-0.9392936,
-0.06097635,
-0.5325453,
-0.02495989,
-0.1493852,
-0.09633294,
0.1275553,
0.2340719,
-0.030119,... |
Muscle pouch implantation: an ectopic bone formation model. | Ectopic bone formation refers to the ossification of tissue outside of its typical microenvironment. Numerous animal models exist to experimentally induce ectopic bone formation in order to examine the process of osteogenesis or to evaluate the "osteogenic potential" of a given implant. The most widely employed methods... | 25,173,383 | [
-0.1753602,
-0.08047441,
-0.1579404,
0.03468663,
-0.1341119,
-0.184229,
-0.1459277,
0.2138994,
0.1815616,
-0.06525914,
-0.0588203,
-0.09405029,
0.04148894,
-0.1961133,
-0.5683259,
-0.1421141,
-0.2457763,
-0.04089428,
-0.08185733,
-0.03201764,
0.3305734,
0.2082604,
0.17075... |
Bone marrow stromal stem cells transplantation in mice with acute spinal cord injury. | Spinal cord injured experimental animals are widely used for studying pathophysiological processes after central nervous system acute traumatic lesion and elaborating therapeutic solutions, some of them based on stem cell transplantation. Here, we describe a protocol of spinal cord contusion in C57BL/6J mice, directly ... | 25,173,389 | [
-0.1490078,
-0.2213847,
0.1946589,
-0.167854,
-0.02996841,
-0.1354331,
-0.2014742,
-0.0400546,
0.004572378,
-0.03469634,
-0.09356521,
-0.08786767,
-0.1018162,
-0.105759,
-0.3916774,
-0.2437556,
0.05697107,
-0.0614536,
-0.2763112,
0.2262402,
0.01454147,
0.03910494,
0.07859... |
Mesenchymal stem cells attenuate rat graft-versus-host disease. | Mesenchymal stem cells (MSCs) derived from bone marrow are feasible for the exertion of a powerful immunoregulatory effect and thus shall hold a curative potency in T lymphocyte-dependent pathologies. This current article is intended to describe the method to investigate that MSCs might take advantage of regulation in ... | 25,173,396 | [
0.4290817,
0.1952904,
-0.3363998,
0.01630797,
0.308029,
-0.1528613,
-0.152237,
0.2843603,
-0.01490949,
-0.1575754,
-0.2705327,
-0.3508983,
0.2062089,
0.2856241,
-0.4269972,
-0.1448748,
-0.3891826,
-0.4394597,
0.1932497,
-0.07702872,
0.05499128,
0.0988519,
0.007087472,
0... |
Puerarin protects against β-amyloid-induced microglia apoptosis via a PI3K-dependent signaling pathway. | Puerarin extracted from Radix puerariae is well-known for its anti-oxidative and neuroprotective activities. In this study, we investigated the protective effect of puerarin on amyloid-β protein (Aβ)-induced cytotoxicity and its potential mechanisms in BV-2 and primary microglial cells. We found that pretreatment with ... | 25,173,404 | [
-0.3796835,
0.1999011,
0.3500581,
0.06231385,
0.1435598,
0.1230563,
0.1209748,
0.1099928,
0.1040761,
0.1628435,
0.1706383,
-0.1214276,
-0.1963173,
0.09231239,
-0.04392196,
0.1981817,
-0.3338664,
0.2928776,
-0.1554003,
0.08839457,
0.06960767,
0.3253488,
0.1556544,
-0.142... |
Effect of physical activity level on biomarkers of inflammation and insulin resistance over 5 years in outpatients with coronary heart disease (from the Heart and Soul Study). | Higher levels of physical activity are associated with lower rates of coronary heart disease (CHD). Previous studies have suggested that this is due partly to lower levels of inflammation and insulin resistance. The aim of this study was to determine whether physical activity level was associated with inflammation or i... | 25,173,442 | [
0.003131905,
-0.0736713,
-0.3824383,
-0.2220649,
-0.285162,
-0.1532274,
-0.06606758,
0.3837737,
-0.151807,
-0.07577507,
0.001524677,
0.1925909,
-0.03255368,
-0.5715914,
0.2146069,
-0.01012041,
-0.4911702,
0.03519014,
0.03421037,
0.2992102,
-0.2808239,
-0.08371329,
-0.2021... |
Chronic social instability stress enhances vulnerability of BDNF response to LPS in the limbic structures of female rats: a protective role of antidepressants. | The aim of the present study was to estimate the influence of antidepressants given chronically on brain-derived neurotrophic factor (BDNF) alterations induced by lipopolysaccharide (LPS) in the amygdala and hippocampus of female rats subjected to chronic social instability stress (CSIS) for 29-30 days. CSIS was used a... | 25,173,454 | [
0.1790797,
0.1360313,
0.177123,
-0.09576377,
0.1456599,
-0.509545,
-0.09905111,
-0.3570693,
-0.3390107,
-0.1068887,
-0.1294202,
-0.2526701,
-0.05183369,
0.1994492,
-0.05133552,
-0.1246986,
-0.3590591,
0.0460503,
-0.02092169,
0.28493,
-0.2052258,
0.1687141,
0.03890574,
-... |
Inherited macrothrombocytopenias. | Inherited macrothrombocytopenias are a clinically heterogeneous group of disorders, many of which cause moderate-to-severe bleeding tendencies in affected individuals, but which remain under-recognized and are frequently misdiagnosed as immune thrombocytopenia purpura. Diagnostic strategies to date have included a pred... | 25,173,502 | [
-0.003153469,
0.01070158,
-0.07330193,
-0.4267557,
-0.03147366,
-0.1618895,
0.1355592,
-0.04676327,
-0.199045,
0.07179556,
0.1551552,
0.4269888,
-0.03799694,
-0.2075081,
-0.2262782,
-0.3097068,
-0.1480671,
0.01876517,
-0.004804791,
0.05307965,
0.1742768,
0.2116484,
-0.093... |
Using a low-amplitude RF pulse at echo time (LARFET) for device localization in MRI. | We describe a new method for frequency down-conversion of MR signals acquired with the radio-frequency projections method for device localization. A low-amplitude, off-center RF pulse applied simultaneously with the echo signal is utilized as the reference for frequency down-conversion. Because of the low-amplitude and... | 25,173,518 | [
-0.03370108,
0.08226056,
-0.003839593,
0.02960768,
-0.2418509,
-0.3039075,
0.0749326,
0.0687712,
0.2540118,
0.1741472,
-0.08039808,
-0.05026655,
0.3528395,
-0.1549986,
-0.8844013,
-0.1845082,
-0.2036939,
0.1556358,
-0.1408293,
-0.2793423,
0.1989586,
0.1294133,
0.02835075,... |
Suboptimal risk factor control in patients undergoing elective coronary or peripheral percutaneous intervention. | The American Heart Association recommends targeting 7 cardiovascular (CV) health metrics to reduce morbidity and mortality. Control of these targets in patients undergoing CV intervention is uncertain. We prospectively studied patients undergoing elective percutaneous coronary or peripheral intervention from November 2... | 25,173,542 | [
-0.2215032,
0.2102122,
-0.34023,
-0.1618258,
-0.1182963,
-0.07929939,
-0.09607742,
0.2383654,
0.09975212,
-0.299092,
0.08131762,
0.1726941,
-0.07543286,
-0.4001848,
0.09072832,
0.2021167,
-0.3401257,
0.08193181,
0.1061492,
0.1967452,
-0.4026546,
0.1366052,
-0.03471161,
... |
Current role of anti-angiogenic strategies for glioblastoma. | Glioblastoma, an incurable, malignant, and highly vascular tumor, is a seemingly ideal target for anti-angiogenic therapies such as bevacizumab, an anti-vascular endothelial growth factor (VEGF) monoclonal antibody. Phase II trials in recurrent glioblastoma demonstrated bevacizumab was associated with clinical benefits... | 25,173,555 | [
-0.1184744,
0.3016701,
0.0944618,
-0.5099965,
0.05570702,
-0.1448409,
0.1316637,
-0.1460384,
-0.0908936,
0.0963078,
-0.03230033,
0.0149871,
-0.3432171,
-0.1105699,
-0.4997523,
-0.1758677,
-0.08940107,
0.6881593,
-0.03371843,
0.392181,
-0.1103491,
0.2274947,
-0.01969834,
... |
SeqCompress: an algorithm for biological sequence compression. | The growth of Next Generation Sequencing technologies presents significant research challenges, specifically to design bioinformatics tools that handle massive amount of data efficiently. Biological sequence data storage cost has become a noticeable proportion of total cost in the generation and analysis. Particularly ... | 25,173,568 | [
-0.06277632,
0.1319394,
0.03655659,
-0.1293087,
0.07925557,
-0.3017138,
-0.06524545,
-0.03029696,
0.04597409,
-0.1393601,
-0.2328953,
-0.133843,
0.1617286,
0.2622325,
-0.6802307,
0.08687088,
0.1091336,
-0.09618754,
0.003973609,
-0.1673409,
0.46812,
-0.1814552,
-0.2017677,... |
Large scale comparison of non-human sequences in human sequencing data. | Several studies have demonstrated that unmapped reads in next generation sequencing data could be used to identify infectious agents or structural variants, but there has been no intensive effort to analyze and classify all non-human sequences found in individual large data sets. To identify commonality in non-human se... | 25,173,571 | [
-0.3324535,
0.2809132,
-0.1595917,
-0.06012556,
0.07026035,
0.01860079,
-0.0669849,
0.01783786,
0.2155318,
-0.05223235,
-0.1456509,
-0.04035904,
0.2281576,
-0.0214319,
-0.4368147,
-0.1769141,
0.2162376,
-0.01607675,
-0.07270389,
-0.3433197,
0.1999485,
0.316213,
-0.1442761... |
Phase-engineered low-resistance contacts for ultrathin MoS2 transistors. | Ultrathin molybdenum disulphide (MoS2) has emerged as an interesting layered semiconductor because of its finite energy bandgap and the absence of dangling bonds. However, metals deposited on the semiconducting 2H phase usually form high-resistance (0.7 kΩ μm-10 kΩ μm) contacts, leading to Schottky-limited transport. I... | 25,173,581 | [
-0.2927161,
0.07116915,
-0.4204633,
-0.2729405,
0.02069295,
-0.1990685,
-0.2086337,
-0.1929937,
-0.06896204,
0.03943025,
-0.01426492,
-0.2961656,
0.07676057,
0.09570265,
-0.5554553,
-0.2626811,
-0.3233467,
-0.02312798,
-0.08545986,
0.09756822,
-0.0766436,
0.1336623,
-0.06... |
Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period. | The purpose of this study was to analyze the influence of age on both the risk of hepatectomy and the prognosis in patients with hepatocellular carcinoma (HCC). Patients undergoing an initial hepatectomy for HCC were classified into 2 age groups: 75 years or over (n = 113) and less than 75 years (n = 499). A zero 90-da... | 25,173,600 | [
0.03312838,
-0.0926623,
-0.2617457,
-0.2478809,
-0.06857077,
-0.1943386,
0.09685294,
-0.2760094,
-0.1176283,
0.08904449,
-0.0859476,
0.2546067,
-0.1773023,
-0.1721374,
-0.3813672,
-0.3358588,
0.3403323,
0.4958205,
0.1595167,
0.006032897,
-0.02379034,
0.45213,
-0.117418,
... |
Genetically encoded tools for RNA imaging in living cells. | RNA imaging probes help us investigate how transport and dynamics of RNA contribute to subcellular RNA localization or regulation of gene expression. Out of the plethora of strategies that have been developed to image RNA in living cells, genetically encoded probes are interesting because they can be produced by the ce... | 25,173,610 | [
-0.1584541,
-0.06215276,
-0.1145946,
-0.05680634,
0.09115283,
-0.2684547,
-0.06829861,
0.09866452,
0.1979383,
-0.03900056,
0.07426117,
0.03576105,
0.1724492,
-0.1298717,
-0.6055793,
-0.1356564,
-0.5250441,
0.1441793,
-0.2856799,
-0.08095329,
0.3116238,
0.1398695,
-0.41580... |
In silico identification of potential virulence genes in 1,3-propanediol producer Klebsiella pneumonia. | The pathogenic characteristics of Klebsiella pneumoniae could pose security risks for industrial applications. In this study, the existence and distribution of 2457 known virulence genes (VFs) in 9 strains of K. pneumoniae were systematically analyzed by high-throughput in silico methods. We found different numbers and... | 25,173,613 | [
-0.1985878,
-0.1021301,
-0.05219619,
-0.3066155,
0.1495043,
0.2410039,
-0.01783767,
0.04047605,
-0.1257064,
-0.2443781,
0.2835276,
-0.1249701,
-0.2864379,
0.2258169,
-0.2905136,
0.01570814,
-0.1718885,
0.345404,
0.2956359,
0.1294101,
0.1167045,
0.2811985,
-0.2804652,
0.... |
Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation. | Bioreactor process parameters influence the N-linked glycosylation profile of the produced monoclonal antibodies. A systematic assessment of their impact is a prerequisite for providing controllability over glycosylation, one of the most critical quality attributes of therapeutic antibodies. In this study we investigat... | 25,173,615 | [
-0.1293686,
-0.07744095,
-0.07255691,
0.1717797,
-0.06255195,
0.06666306,
-0.00904032,
0.3750245,
-0.04092848,
-0.04999954,
0.07279935,
-0.3978865,
-0.08732783,
-0.3302102,
0.01598869,
0.04542026,
-0.02857989,
-0.09726519,
-0.1878407,
0.2233886,
0.2750034,
0.2607973,
-0.1... |
The association of red blood cell distribution width with anemia and inflammation in patients with Takayasu arteritis. | Red blood cell distribution width (RDW) has been shown to be related to both anemia and inflammation in various diseases. However, the role of RDW in patients with Takayasu arteritis (TA) is unknown. Therefore, we investigated the association of RDW with anemia, inflammation, and disease activity in TA. RDW was determi... | 25,173,627 | [
0.06420629,
-0.2018122,
-0.0732217,
-0.1161592,
0.03824902,
-0.05057536,
0.5992755,
0.3692446,
0.06427523,
-0.006176502,
0.2770949,
0.112176,
-0.2402203,
0.04341281,
-0.174519,
-0.2381132,
-0.2458976,
0.2683543,
0.0403146,
-0.1925765,
-0.1241834,
0.06710568,
-0.1166067,
... |
L-Carnitine ester of prednisolone: pharmacokinetic and pharmacodynamic evaluation of a type I prodrug. | To evaluate whether PDSC, an L-carnitine ester derivative of prednisolone and OCTN2 substrate, could provide a targeted delivery of the corticosteroid into the lung tissues of an asthmatic guinea pig model. PRED (prednisolone) and PDC (an L-carnitine prodrug of prednisolone not recognized by OCTN2) served as controls. ... | 25,173,636 | [
0.3095379,
-0.2382005,
-0.1387787,
-0.04299937,
0.03053255,
-0.03694759,
0.02174742,
0.1250025,
0.1499381,
-0.1583527,
-0.07069023,
0.09009279,
0.1388571,
0.6554196,
-0.5068756,
0.009767463,
-0.5700662,
0.05384266,
0.2954269,
0.22908,
-0.159532,
0.1149383,
-0.1777532,
-... |
Myocardial infarction worsens glomerular injury and microalbuminuria in rats with pre-existing renal impairment accompanied by the activation of ER stress and inflammation. | Deterioration of renal function occurs after chronic heart failure in approximately one-third of patients, particularly in those with pre-existing renal impairment such as diabetic nephropathy. Impaired renal function in these patients is always associated with a worse prognosis. However, the mechanisms underlying such... | 25,173,645 | [
-0.2433836,
0.1914542,
-0.2018969,
-0.2307627,
0.1736563,
-0.3990981,
-0.3134651,
0.1177152,
0.01940953,
0.1140268,
0.2336443,
-0.07482143,
0.1187864,
0.03057341,
-0.4781635,
0.02052952,
0.00398362,
0.03188187,
-0.005956138,
-0.02013251,
-0.1106419,
0.2337015,
-0.1890036,... |
Radiation-induced effects to nontarget abdominal and pelvic viscera. | Radiation injuries often occur during or after radiation therapy in the abdomen or pelvis. Although any organ in the abdomen or pelvis may be exposed to and injured by radiation therapy directed to a nearby organ, this article focuses on more frequently encountered imaging findings of inadvertent radiation damage. It i... | 25,173,657 | [
-0.2773732,
-0.1706096,
-0.1422386,
-0.1552204,
0.0177644,
-0.04492571,
-0.2760941,
-0.3268898,
0.1235415,
0.1212443,
0.3350585,
-0.2076705,
-0.06901621,
-0.1959927,
-0.4033461,
-0.1341275,
-0.4101845,
0.1576508,
0.1359768,
-0.1109519,
-0.04428145,
0.08978422,
-0.03100801... |
Prehospital fluid resuscitation in hypotensive trauma patients: do we need a tailored approach? | The ideal strategy for prehospital intravenous fluid resuscitation in trauma remains unclear. Fluid resuscitation may reverse shock but aggravate bleeding by raising blood pressure and haemodilution. We examined the effect of prehospital i.v. fluid on the physiologic status and need for blood transfusion in hypotensive... | 25,173,671 | [
-0.2264228,
0.09830719,
-0.4614163,
-0.364103,
0.1147018,
-0.1869781,
0.008836026,
-0.3446751,
-0.2353305,
-0.03114972,
0.1941308,
0.4008071,
-0.1537084,
-0.2038007,
-0.1673701,
-0.2132468,
-0.09840059,
0.3160626,
-0.2478998,
0.02660332,
0.001768937,
-0.03600618,
0.133322... |
Effect of lactoferrin on odontogenic differentiation of stem cells derived from human 3rd molar tooth germ. | Stem cell technology has been a great hope for the treatment of many common tissue regeneration-related diseases. Therefore, the main challenge in hard tissue engineering is to make a successful combination of stem cells and efficient inductors such as biomaterials or growth factors, in the concept of stem cell convers... | 25,173,676 | [
0.1510216,
-0.04716491,
-0.01195647,
0.3265292,
0.08980281,
-0.3441941,
-0.0751482,
0.1401561,
0.3126006,
-0.07283986,
-0.3090172,
0.1266327,
-0.29535,
-0.2389056,
-0.6431014,
-0.08678113,
-0.03784555,
-0.3200654,
-0.3389825,
-0.156291,
0.3683085,
0.4837784,
-0.1707178,
... |
Association between serum sulfatide and carotid intima media thickness in patients with familial hypercholesterolemia. | There is a positive association between sulfatide and atherosclerosis in an animal model for human familial hypercholesterolemia. Carotid intima-media thickness (IMT) is thought to be a marker of atherosclerosis in humans. We investigated the relationship between sulfatide and carotid IMT in heterozygous familial hyper... | 25,173,691 | [
0.1321014,
0.1902868,
-0.3423346,
-0.1423799,
0.3047123,
-0.3951562,
0.04447869,
0.1050502,
0.01487953,
-0.1040859,
0.3342829,
0.3016475,
0.009559176,
-0.08098436,
0.223717,
-0.03625667,
-0.6237386,
-0.2188703,
-0.06776442,
-0.01990836,
-0.4362705,
-0.002611783,
-0.258492... |
Characteristics of biochars from crop residues: potential for carbon sequestration and soil amendment. | Biochar has potential to sequester carbon in soils and simultaneously improve soil quality and plant growth. More understanding of biochar variation is needed to optimise these potential benefits. Slow pyrolysis at 600 °C was undertaken to determine how yields and characteristics of biochars differ when produced from e... | 25,173,727 | [
0.2685317,
0.3610951,
0.2229007,
-0.2070108,
-0.1991379,
0.08157438,
-0.03947591,
-0.07524501,
0.0684178,
0.05541011,
-0.06998628,
0.1147837,
-0.1577792,
0.08234414,
-0.6480292,
-0.1753378,
-0.06724391,
0.4114516,
0.2648477,
-0.1541083,
-0.1165228,
0.4296149,
-0.1071922,
... |
Redox and catalysis 'all-in-one' infinite coordination polymer for electrochemical immunosensor of tumor markers. | Prostate-specific antigen (PSA), as a glycoprotein enzyme encoded in humans by the KLK3 gene, is one of the most important biomarkers for the diagnosis and prognosis of prostate cancer. Herein, a new electrochemical immunosensor for sensitive determination of PSA was designed by using redox and catalysis 'all-in-one' i... | 25,173,732 | [
0.2564825,
-0.03981395,
-0.0654907,
0.1581236,
-0.5054464,
-0.1640848,
-0.1436233,
0.4770352,
0.1050499,
0.05977886,
0.1354421,
0.1266104,
0.09221161,
0.04865882,
-0.4755511,
-0.1313233,
-0.5895828,
-0.3075182,
-0.07999346,
-0.01212441,
0.4167519,
0.2709426,
-0.1795634,
... |
Functional lysophosphatidic acid receptors expressed in Oryzias latipes. | Lysophosphatidic acid (LPA) signaling is known to play biological and pathophysiological roles in many types of animals. Medaka (Oryzias latipes) is an experimental fish that can be easily maintained, propagated, and analyzed, and whose genome has been completely sequenced. However, there is limited information availab... | 25,173,740 | [
0.2783164,
-0.3848454,
0.1305055,
-0.01961671,
0.06314237,
0.1320335,
0.1698072,
0.3569029,
0.05832463,
-0.4736332,
0.2963239,
-0.06613181,
-0.1411125,
0.08574342,
-0.2529768,
0.02057286,
-0.3242747,
0.2748873,
0.06343815,
-0.02000702,
0.1926741,
0.5349497,
-0.2911114,
... |
Glucagon-like peptide-2 regulates release of chylomicrons from the intestine. | The intestine efficiently incorporates and rapidly secretes dietary fat as chylomicrons (lipoprotein particles comprising triglycerides, phospholipids, cholesterol, and proteins) that contain the apolipoprotein isoform apoB-48. The gut can store lipids for many hours after their ingestion, and release them in chylomicr... | 25,173,752 | [
0.2350316,
-0.2875443,
-0.4585336,
-0.1363208,
0.2540777,
-0.4218599,
-0.181603,
0.427507,
0.215077,
-0.0782206,
-0.04610495,
-0.1845904,
-0.002277087,
-0.08999716,
-0.09643856,
-0.326297,
-0.5520087,
-0.07733199,
-0.2671423,
0.1353292,
-0.1056444,
0.3666666,
-0.004110345... |
Association between serum concentration of infliximab and efficacy in adult patients with ulcerative colitis. | We analyzed data collected during the Active Ulcerative Colitis Trials (ACT-1 and ACT-2) to assess relationships between serum concentrations of infliximab and outcomes of adults with moderate-to-severe ulcerative colitis. We compared serum concentrations of infliximab with outcomes of 728 patients with moderately-to-s... | 25,173,754 | [
0.1930733,
-0.2137249,
-0.07152207,
-0.4538934,
-0.1715602,
-0.1573878,
-0.2577858,
0.3829384,
0.4344584,
-0.08173742,
-0.04998586,
-0.304827,
0.254106,
0.09799232,
0.08887348,
-0.1771937,
-0.2287322,
-0.1826681,
0.03006161,
0.3675036,
0.05120083,
0.1525249,
-0.05300319,
... |
Ofloxacin sorption in soils after long-term tillage: the contribution of organic and mineral compositions. | Intensive human activities in agricultural areas resulted in significant alteration of soil properties, which consequently change their interactions with various contaminants. This process needs to be incorporated in contaminant behavior prediction and their risk assessment. However, the relevant study is missing. This... | 25,173,763 | [
0.0793342,
0.5292023,
0.4632279,
0.3653126,
-0.09201363,
-0.201209,
-0.3763188,
0.4188542,
0.08631211,
-0.2619525,
-0.2551853,
-0.07185672,
0.04756066,
0.2697904,
-0.2621766,
0.2349319,
-0.3901365,
0.1796549,
-0.2328842,
0.2383493,
0.4679818,
0.2997586,
-0.07408211,
0.1... |
The interaction of glucocorticoids and progesterone distinctively affects epithelial sodium transport. | Glucocorticoids and progesterone exert stimulatory effects on epithelial Na(+) transport, including increased mRNA expression of the participating ion transporters (epithelial Na(+) channels [ENaC] and Na,K-ATPases) and their electrophysiological activity. Fetuses threatened by preterm labor may receive high doses of g... | 25,173,779 | [
0.06948198,
-0.1184199,
-0.3931607,
0.007843284,
0.1068201,
-0.03248915,
0.02203788,
0.2127292,
0.05350069,
0.2644849,
0.05032193,
-0.2803932,
0.1677207,
-0.3367368,
-0.2148089,
-0.3813545,
-0.2849403,
-0.2241862,
-0.2882436,
0.02758037,
0.5687397,
-0.142622,
-0.13304,
... |
Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells. | The aim of this study was to focus on hexavalent chromium, [Cr(VI)], a chemical carcinogen and major public health concern, and consider its ability to impact DNA double strand break repair. We further focused on particulate Cr(VI), because it is the more potent carcinogenic form of Cr(VI). DNA double strand break repa... | 25,173,789 | [
0.08629465,
-0.2123608,
-0.2166222,
-0.2363121,
-0.1655909,
-0.01520151,
0.1263524,
0.3152372,
0.05222858,
0.3809768,
0.1788816,
0.1355251,
-0.3459884,
-0.04613845,
-0.3259954,
-0.2818384,
-0.007025608,
0.006397642,
0.2840719,
0.04593502,
0.150884,
0.3811364,
0.04653893,
... |
Comparison of anorectic and emetic potencies of deoxynivalenol (vomitoxin) to the plant metabolite deoxynivalenol-3-glucoside and synthetic deoxynivalenol derivatives EN139528 and EN139544. | The mycotoxin deoxynivalenol (DON) elicits robust anorectic and emetic effects in several animal species. However, less is known about the potential for naturally occurring and synthetic congeners of this trichothecene to cause analogous responses. Here we tested the hypothesis that alterations in DON structure found i... | 25,173,790 | [
-0.141002,
0.1420757,
-0.2106465,
-0.1043387,
0.4550185,
0.0003527721,
-0.03173321,
0.0461361,
0.3182979,
-0.1489962,
0.1080024,
-0.2519565,
-0.06251767,
-0.2143514,
-0.4211258,
-0.2295007,
-0.595888,
0.2206054,
0.528303,
-0.06514324,
-0.1342059,
0.5038175,
-0.2856112,
... |
Modulating cancer multidrug resistance by sertraline in combination with a nanomedicine. | Inherent and acquired multiple drug resistance (MDR) to chemotherapeutic drugs is a major obstacle in cancer treatment. The ATP Binding Cassettes (ABC) transporter super family that act as extrusion pumps such as P-glycoprotein and multidrug-resistance-associated-proteins have prominent roles in cancer MDR. One of the ... | 25,173,796 | [
-0.2186558,
-0.2342138,
0.02361643,
-0.1500709,
0.02508638,
-0.2561191,
0.1693945,
0.2400966,
0.1287573,
-0.1628132,
-0.09732903,
0.1644297,
-0.07900186,
0.3452362,
-0.6058584,
0.07333476,
-0.5021305,
-0.004847975,
0.06641787,
0.04080172,
-0.01970718,
0.1870236,
-0.116274... |
The mechanistic basis of arsenicosis: pathogenesis of skin cancer. | Significant amounts of arsenic have been found in the groundwater of many countries including Argentina, Bangladesh, Chile, China, India, Mexico, and the United States with an estimated 200 million people at risk of toxic exposure. Although chronic arsenic poisoning damages many organ systems, it usually first presents... | 25,173,797 | [
-0.2143267,
-0.2382757,
0.3070111,
-0.3006901,
-0.1319985,
-0.2193209,
-0.145475,
0.001691046,
0.07123953,
-0.06563727,
-0.08941495,
-0.09748943,
-0.3620736,
0.0311379,
-0.3544871,
-0.01480749,
-0.09571888,
-0.09744842,
0.35515,
-0.1826514,
0.3528253,
0.4135663,
-0.311669... |
PGC-1α and PGC-1β increase CrT expression and creatine uptake in myotubes via ERRα. | Intramuscular creatine plays a crucial role in maintaining skeletal muscle energy homeostasis, and its entry into the cell is dependent upon the sodium chloride dependent Creatine Transporter (CrT; Slc6a8). CrT activity is regulated by a number of factors including extra- and intracellular creatine concentrations, horm... | 25,173,818 | [
-0.08473299,
0.224483,
-0.01453029,
-0.07157657,
-0.3532277,
-0.2453832,
-0.1738626,
-0.01403838,
-0.196952,
0.1657131,
0.2192444,
0.4055004,
0.04269045,
0.4944189,
-0.270997,
0.05824524,
-0.3239342,
-0.1696774,
-0.09942815,
-0.2301923,
0.1197682,
0.2252423,
0.04659723,
... |
Objectification of the severity of Reinke's edema. | According to the severity, Reinke's edema (RE) of the vocal folds can be divided into three stages as classified by Yonekawa. We evaluated open and closed quotients of vocal folds vibratory cycles using Videostrobokymography (VSK) in a cohort of patients with RE. Parameters were measured from the anterior, medial and p... | 25,173,824 | [
-0.2817257,
0.1569365,
-0.2639142,
-0.5293796,
-0.07416304,
-0.2202902,
0.06939847,
0.06624474,
0.2695948,
-0.04587302,
0.2199793,
-0.1955448,
-0.4173781,
-0.3477374,
0.1636321,
-0.1586263,
-0.2384601,
-0.0112087,
0.1346042,
-0.3000695,
0.3600781,
0.07476421,
-0.3278286,
... |
Synthesis of novel polysubstituted (2SR,4RS)-2-heteroaryltetrahydro-1,4-epoxy-1-benzazepines and cis-2-heteroaryl-4-hydroxytetrahydro-1H-1-benzazepines as antiparasitic agents. | New series of polysubstituted (2SR,4RS)-2-heteroaryltetrahydro-1,4-epoxy-1-benzazepines and cis-2-heteroaryl-4-hydroxytetrahydro-1H-1-benzazepines were designed and synthesized in moderate to high yields using a three-step procedure from ortho-allylanilines. Their antiparasitic activity was evaluated against the extrac... | 25,173,828 | [
-0.2536639,
0.1662014,
-0.01625813,
-0.09047058,
-0.08225928,
-0.158463,
-0.3459392,
0.1830377,
0.2440938,
-0.2916031,
-0.061281,
0.3113575,
-0.04141968,
0.3219061,
-0.4733432,
-0.1798953,
-0.5755419,
0.04312172,
-0.2068777,
0.2924488,
0.1083443,
0.664405,
-0.1856432,
0... |
Valley and band structure engineering of folded MoS(2) bilayers. | Artificial structures made of stacked two-dimensional crystals have recently been the focus of intense research activity. As in twisted or stacked graphene layers, these structures can show unusual behaviours and new phenomena. Among the various layered compounds that can be exfoliated, transition-metal dichalcogenides... | 25,173,830 | [
-0.1659784,
0.3182246,
-0.1900567,
-0.08022928,
0.08600504,
-0.1207017,
-0.310146,
0.02678141,
0.1159364,
-0.1216257,
-0.1269209,
-0.3578749,
-0.04747886,
0.04850909,
-0.6441257,
0.05017782,
-0.3542554,
0.1174455,
-0.05695118,
0.1727531,
0.2785632,
0.1598206,
-0.2784065,
... |
Fingerprint of persistent organic pollutants in tissues of Antarctic notothenioid fish. | In the present work, persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and metabolites, polybrominated diphenyl ethers (PBDEs), and hexachlorocyclohexane (HCH) were analyzed in three Antarctic notothenioids fish species: Trematomus newnesi (TRN), Notot... | 25,173,865 | [
-0.3909731,
0.1710223,
0.1862097,
-0.2370342,
-0.07252837,
-0.1394999,
-0.3402859,
0.2012703,
-0.09260947,
0.08262782,
0.0392279,
-0.1303074,
0.145768,
0.08675988,
-0.3341152,
-0.3098781,
-0.4173421,
0.1939744,
0.4220253,
0.5864949,
0.07317553,
0.6364298,
-0.3217342,
-0... |
N-way partial least squares with variable importance in projection combined to GC × GC-TOFMS as a reliable tool for toxicity identification of fresh and weathered crude oils. | In this study, N-way partial least squares (NPLS) is proposed to correlate comprehensive two-dimensional gas chromatography-time of flight mass spectrometry (GC × GC-TOFMS) data of different aromatic oil fractions (fresh and weathered) to their toxicity values. Before NPLS modeling, since drift and wander of baseline i... | 25,173,867 | [
-0.1366087,
0.2041648,
0.1278396,
-0.1951017,
0.227534,
-0.1400086,
-0.1458151,
-0.1393528,
0.3386484,
-0.03724644,
-0.05032298,
0.05003024,
-0.05478707,
-0.01752737,
-0.500454,
-0.0007608749,
-0.2318003,
0.4078426,
-0.08278733,
0.3503107,
-0.3189311,
0.246554,
-0.1699552... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.