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Evaluation of a fully human monoclonal antibody against multiple influenza A viral strains in mice and a pandemic H1N1 strain in nonhuman primates.
Influenza virus is a global health concern due to its unpredictable pandemic potential. Frequent mutations of surface molecules, hemagglutinin (HA) and neuraminidase (NA), contribute to low efficacy of the annual flu vaccine and therapeutic resistance to standard antiviral agents. The populations at high risk of influe...
25,218,949
[ 0.06307409, -0.2117877, -0.1649709, -0.3662592, -0.03672753, -0.2200456, -0.03044869, 0.1550961, -0.09114788, -0.1845832, 0.0421865, 0.1290129, -0.02278729, -0.1345987, -0.09374764, -0.2074307, -0.110075, -0.2979733, -0.01477724, 0.1116944, 0.3249705, 0.1499378, -0.514388...
Evaluation of levonorgestrel intrauterine system upon presumed nonintact removal.
A 51 year old woman presented for removal of her expired levonorgestrel intrauterine device (IUD). The IUD arms appeared absent upon IUD removal. Further examination of the device revealed that the arms were concealed inside the hormonal cylinder. Recognizing abnormal presentations of the levonorgestrel IUD upon remova...
25,218,958
[ -0.2156537, 0.2333493, 0.1992915, -0.09327141, 0.1037857, -0.1450821, -0.304633, -0.183228, 0.275272, -0.08168024, 0.272469, 0.3176274, 0.1011349, 0.1202957, -0.0674733, -0.02175762, -0.1820421, 0.08938256, -0.2598928, -0.4741878, 0.2138205, 0.08614274, 0.1318906, 0.368...
Time and distance to first accident and driving patterns of young drivers with pay-as-you-drive insurance.
We conducted a study of approximately 16,000 drivers under the age of 30 that had purchased a pay-as-you-drive insurance policy, where their risk of being involved in a crash was analyzed from vehicle tracking data using a global positioning system. The comparison of novice vs. experienced young drivers shows that vehi...
25,218,977
[ -0.2918455, 0.2300897, -0.5955688, 0.3437412, -0.02553673, -0.2155582, -0.09161627, -0.1928459, -0.1812187, -0.04675134, -0.1166779, -0.2331665, 0.04214234, -0.1375565, -0.5526937, -0.4102065, 0.1515271, 0.1383925, -0.3907999, -0.3629812, 0.2570753, 0.324102, -0.2754659, ...
The role of voltage-operated and non-voltage-operated calcium channels in endothelin-induced vasoconstriction of rat cerebral arteries.
Endothelin-1 has been identified as a potential mediator in the pathogenesis of ischaemic stroke and cerebral vasospasm. The aim of this study was to analyse the role of voltage-operated calcium channels (VOCC) and non-VOCC in endothelin-1 induced vasoconstriction of rat cerebral arteries. Arterial segments were dissec...
25,218,985
[ -0.2962585, 0.09836088, -0.3654769, -0.695761, 0.160901, 0.2221048, -0.2831121, -0.2879948, 0.1717089, -0.05334847, -0.05557013, 0.2784048, -0.1349491, -0.1732817, -0.5604245, -0.3097337, -0.5583714, 0.4951215, -0.1019576, 0.3113255, 0.1481826, 0.1907954, 0.02240999, -0...
Power spectral differences of electrophysiological signals detected at acupuncture points and non-acupuncture points.
In this study, we chose 10 acupoints and non-acupuncture point control groups to see if there are electrical differences between acupoints and non-acupoints. 4 adjacent non-acupoints around each acupoint were chosen as a control group in 400 trials on 10 volunteers aged 23-30 years to characterize the Power Spectral De...
25,219,030
[ -0.06096812, 0.2619504, -0.03702872, 0.1329271, 0.2655114, -0.2458033, -0.234627, 0.1175846, 0.04113735, -0.10252, -0.1413265, 0.03966196, 0.1310957, -0.2705609, -0.4030962, -0.07333503, -0.4765403, -0.06429255, -0.2356835, -0.06632909, 0.1576154, 0.3372476, -0.1842867, ...
[The academician Yuri Pavlovitch Lisytsyn and development of public health in Russia].
The scientific input of academician Yu.P Lisytsyn into development of social hygiene, public health and history of medicine is discussed.
25,219,042
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Dual hybrid suite 'a first' for the UK.
A new 6.4 million pounds sterling dual hybrid endovascular theatre suite at the Manchester Royal Infirmary (MRI), which the Central Manchester University Hospitals NHS Foundation Trust (CMFT) says will 'transform the treatment of patients undergoing minimally invasive vascular and cardiac procedures', has recently come...
25,219,084
[ -0.08971249, 0.2043302, -0.09423616, -0.2335957, 0.2920225, -0.3337036, -0.2019716, 0.1565936, 0.1729644, 0.1735192, 0.03899957, 0.02576461, 0.1102846, -0.1942352, -0.234119, -0.2707021, -0.3778997, 0.09589948, -0.007955336, -0.3158601, 0.1549585, 0.1301757, -0.1333456, ...
[NUG--necrotizing ulcerative gingivitis: a review].
Necrotizing Ulcerative Gingivitis (NUG) is an acute and rare (0.5-11% of the population) infectious disease of the gum tissue, which is characterized by ulceration and inflammation of the inter-dental gum tissue. NUG was documented by historians since the fourth century BC, most of the reports from the ancient world we...
25,219,100
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Hypersensitivity reactions to biological drugs.
Strictly speaking, biological drugs are defined as drugs obtained using biotechnology that act on the immune system. They encompass monoclonal antibodies, fusion proteins, and cytokines. Although they are restricted to specific diseases, they have been increasingly used in recent years, with the consequent reporting of...
25,219,103
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Oral immunotherapy in children with IgE-mediated wheat allergy: outcome and molecular changes.
IgE-mediated wheat allergy affects around 0.5% of the population, and current management is based on avoidance. We propose an active intervention to promote tolerance in wheat-allergic children. To investigate the efficacy and safety of an oral immunotherapy (OIT) protocol with wheat to treat IgE-mediated wheat-allergi...
25,219,106
[ 0.2588301, -0.1096542, 0.1471775, -0.3134688, 0.07236566, -0.4992716, -0.118052, 0.3222657, 0.2284732, -0.0762028, 0.09690668, 0.06704856, 0.02266082, -0.285615, -0.3091294, -0.03124117, -0.2892333, 0.0150988, 0.0954904, 0.1577349, -0.1314639, 0.7104139, -0.2652563, 0.0...
[Effects of acupuncture intervention on expression of glucose-regulated protein 78 and C/EBP homologous protein in hippocampal CA 1 region in rats with hyperspasmia].
To observe the effect of acupuncture intervention on expression of glucose-regulated protein 78 (Grp 78) and C/EBP homologous protein (CHOP) in the hippocampus in epilepsy rats so as to explore its mechanism underlying improvement of hyperspasmia-induced brain injury. Forty-two SD rats were randomly divided into normal...
25,219,120
[ -0.1770929, 0.02658386, -0.08923057, -0.1726787, 0.3220283, -0.2195389, -0.3321666, -0.4570804, 0.008445194, 0.3285582, 0.1335343, 0.3363364, -0.2486664, -0.5210457, -0.3095405, 0.01699378, -0.3551251, 0.1326521, -0.1506211, -0.4155411, -0.1928924, 0.3811801, 0.0457291, ...
[Using functional brain imaging technique to study central mechanism of acupuncture therapy for chronic stable angina pectoris in view of heart-brain correlation].
Heart-brain correlation is an important component of Chinese medicine about the theory of zang-fu organs, which is still valuable for acupuncture clinical practice. Nowadays, increasing evidence supports the close association between the heart-brain axis, central autonomic nerve network and cardiovascular diseases, as ...
25,219,133
[ -0.05423177, 0.4887397, 0.3723126, 0.0765852, 0.285117, -0.205867, -0.2656845, 0.2853165, 0.163383, -0.02281878, -0.1344002, -0.2477893, -0.07122176, -0.4005643, -0.3369691, -0.1422413, -0.4021249, 0.1425584, -0.1842744, 0.05624942, -0.02114725, 0.2128037, -0.3174962, 0...
[The influence of pH and pCO2 levels of umbilical cord blood obtained perinatally on selected parameters of stem cells].
The aim of the study was to demonstrate a correlation between pH and pCO2 levels in umbilical cord blood and the quality of the harvested material. Additionally the effect of pH and pCO2 on the number of cord blood CD34+ cells and their vitality was analyzed. The study included 50 pregnant women after vaginal delivery ...
25,219,137
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The -323P0/P10 factor VII gene polymorphism and the risk of recurrent miscarriage.
Genetically determined disturbances in the activity of coagulation factor VII may lead to obstetric complications. The aim of the study was to evaluate the correlation between -323P0/P10 factor VII gene polymorphism and the risk of recurrent miscarriage. The study group consisted of 152 women with a history of > or ...
25,219,139
[ 0.1337634, 0.04178986, -0.1775473, -0.09625708, 0.2265331, -0.3624957, 0.2546221, -0.1072543, -0.0311246, 0.04296673, 0.08202711, 0.3245139, -0.09471988, -0.3827326, -0.08576488, -0.3225671, -0.3486868, -0.156609, 0.1021152, 0.02063851, 0.2003754, 0.265194, 0.01736239, ...
[Safety of rush allergen-specific immunotherapy in allergic rhinitis patients].
The safety of rush immunotherapy (RIT) in Chinese allergic rhinitis (AR)patients is unknown. The purpose of this prospective was to assess the safety differences between RIT and conventional immunotherapy in Chinese AR patients, and then discuss the clinical application feasibility of RIT. A one-year study period was s...
25,219,200
[ 0.04573969, -0.1662835, 0.01732268, 0.03617568, 0.1630252, -0.4135999, -0.1105197, 0.2657816, 0.170746, -0.1080622, 0.1864897, 0.4090292, 0.07589398, -0.3586934, -0.03167706, -0.05192381, -0.1861012, 0.09849181, 0.1267558, 0.1743393, 0.0505739, 0.5239664, -0.2585514, -0...
[Primary nasopharyngeal tuberculosis presenting as durative aural fullness: one case report and literature review].
To study the clinical features, diagnosis and treatments of primary nasopharyngeal tuberculosis. A case report was presented, and meanwhile etiopathogenesis and differential diagnosis were also reviewed. A biopsy was taken and the histopathological examination showed tuberculosis granuloma with caseous necrosis. After ...
25,219,213
[ -0.320659, -0.1458959, 0.2259003, 0.2926364, -0.1890735, -0.2401557, -0.2324501, 0.04044174, 0.2976043, 0.09416199, 0.233754, 0.373489, -0.009360356, 0.05791822, -0.1815052, -0.07671796, -0.2589545, 0.01269409, -0.3653693, 0.01371405, 0.008883317, 0.1017425, -0.06594376, ...
[Analysis of the level and significance of IL-16 and IL-17 in nasal secretion and in serum of patients with allergic rhinitis and non-allergic rhinitis].
To test the immunoglobulin free light chain (FLC) from nasal secretion and serum of patients with allergic rhinitis(AR)and non-allergic rhinitis(NAR) for the purpose of exploring the possible immunological mechanism. Ninety consecutive patients were selected between January 2009 and January 2012, involving 45 patients ...
25,219,212
[ 0.06512513, -0.3444973, -0.1010552, -0.1245875, 0.3081793, -0.3677405, -0.4396456, -0.1752492, 0.1343261, -0.2572532, 0.2566508, 0.0710924, 0.08924601, -0.03747616, 0.08132458, -0.0274527, -0.3073803, -0.03284992, -0.06109802, 0.4803279, -0.06372837, 0.1302577, -0.2618393...
[Research on increasing X-ray protection capability based on photonic crystal technology].
Light cannot be propagated within the range of photonic crystal band gaps. Based on this unique property, we proposed a method to improve anti-radiation capability through one-dimensional photonic crystal coating. Using transmission matrix method, we determined the appropriate dielectric materials, thickness and period...
25,219,231
[ 0.1042992, 0.2954756, 0.1447067, 0.3669151, 0.0750272, 0.02303257, -0.2679905, -0.02151769, 0.1948701, 0.02726995, 0.03576022, 0.1725098, 0.06231719, 0.2332246, -0.5432258, 0.3085467, -0.05538959, 0.1630514, -0.4031242, 0.2239303, 0.3131655, -0.07794129, -0.2595005, 0.2...
[Data analysis for relationship between aging and cardiothoracic ratio based on C-V segmentation algorithm].
Cardiac enlargement is an important symptom of vascular and heart disease. The cardiothoracic ratio (CTR) is an important index used to measure the size of heart. The aim of this study was to assess the relationship between aging and cardiothoracic ratio. This paper also presents an improved C-V level set method to seg...
25,219,232
[ -0.06311726, 0.02440062, -0.1710492, -0.03338676, 0.1083393, 0.1782165, 0.04529775, 0.1626838, -0.01284283, 0.1673758, 0.1419389, 0.09920232, -0.03901678, 0.04901894, -0.5542099, -0.1624751, -0.06498421, 0.1498159, 0.1368634, 0.3635663, 0.2177079, 0.4055893, -0.4374271, ...
[Significant genes extraction and analysis of gene expression data based on matrix factorization techniques].
It is generally considered that various regulatory activities between genes are contained in the gene expression datasets. Therefore, the underlying gene regulatory relationship and the biologically useful information can be found by modeling the gene regulatory network from the gene expression data. In our study, two ...
25,219,254
[ -0.0693583, 0.3376231, 0.3060006, 0.211528, 0.06568293, -0.1164208, -0.2152957, 0.2560596, 0.3237917, -0.1646287, -0.2216804, 0.1978725, 0.1708229, -0.3990075, -0.1696124, 0.2956766, -0.1938326, 0.2986038, -0.167125, 0.1885575, 0.2248109, 0.1322016, -0.1107698, -0.11359...
[Application of a new design of cryo-jaw and its biomechanical evaluation in rat achilles tendon in vitro].
This study was aimed to design a new, accurate and easy-to-use water bath cryo-jaw, and try to solve the problems met in small animals achilles tendon mechanical testing. The muscle-tendon-bony units were fixed in the clamps. SD rats achilles tendon were randomly divided into group A and B. Group A was tested by the ne...
25,219,256
[ -0.3519527, 0.2957684, -0.2042617, 0.1123637, -0.2819906, -0.1717634, -0.5665123, 0.2993791, 0.1631824, -0.1787405, 0.1165264, 0.1486893, 0.2472108, -0.08772759, -0.2401674, -0.2710972, -0.09378709, -0.06168456, -0.4944672, 0.4367172, 0.1694707, -0.2798429, -0.08677474, ...
One-Health Simulation Modelling: Assessment of Control Strategies Against the Spread of Influenza between Swine and Human Populations Using NAADSM.
Simulation models implemented using a range of parameters offer a useful approach to identifying effective disease intervention strategies. The objective of this study was to investigate the effects of key control strategies to mitigate the simultaneous spread of influenza among and between swine and human populations....
25,219,283
[ -0.3924995, 0.1905571, -0.07170243, -0.0526026, -0.1034919, -0.1058665, -0.04449933, -0.00953638, -0.003507735, -0.1186077, 0.05889677, -0.1213231, 0.06601585, -0.1229999, -0.3335769, 0.06676818, -0.2297848, 0.1092127, -0.05591566, -0.2543916, 0.1511127, 0.1088757, 0.1284...
Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis.
To evaluate the in vitro antifungal activity of apple cider vinegar on Candida spp. involved in denture stomatitis. The microdilution technique was used to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of apple cider vinegar containing 4% maleic acid, and nystatin (cont...
25,219,289
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Effects of specific organs on seed oil accumulation in Brassica napus L.
Seed oil content is an important agricultural characteristic in rapeseed breeding. Genetic analysis shows that the mother plant and the embryo play critical roles in regulating seed oil accumulation. However, the overwhelming majority of previous studies have focused on oil synthesis in the developing seed of rapeseed....
25,219,307
[ 0.4685714, 0.1370533, 0.1349937, 0.09006824, 0.4164934, 0.2967237, -0.09492582, -0.06503953, 0.1469753, -0.05613291, 0.1186045, -0.07207101, -0.08604278, -0.00984023, 0.05328314, 0.1433134, -0.4172761, 0.1968181, -0.3275701, 0.06251224, 0.6903318, 0.6649376, -0.2518955, ...
HnRNP-like proteins as post-transcriptional regulators.
Plant cells contain a diverse repertoire of RNA-binding proteins (RBPs) that coordinate a network of post-transcriptional regulation. RBPs govern diverse developmental processes by modulating the gene expression of specific transcripts. Recent gene annotation and RNA sequencing clearly showed that heterogeneous nuclear...
25,219,311
[ 0.2480341, 0.1578191, 0.0839557, -0.2829487, 0.02322503, -0.3147342, 0.05268668, 0.1567464, -0.02559254, 0.1897994, 0.03920834, 0.1285101, -0.1792977, -0.1006964, -0.2561345, 0.04960589, -0.08777063, 0.170624, 0.2895805, -0.3576191, 0.273306, 0.3591361, -0.2587134, -0.3...
Plant regeneration and biochemical accumulation of hydroxybenzoic and hydroxycinnamic acid derivatives in Hypoxis hemerocallidea organ and callus cultures.
Micropropagation of Hypoxis hemerocallidea Fisch. and C.A. Mey was used as a model system to study the influence of cytokinins (CKs) on plant regeneration and biochemical accumulation of hydroxybenzoic and hydroxycinnamic acid derivatives in organ and callus cultures and their antioxidant activity. Fourteen free phenol...
25,219,317
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Beery-Buktenica Developmental Test of Visual-Motor Integration (Beery-VMI): lessons from exploration of cultural variations in visual-motor integration performance of preschoolers.
Visual-motor integration (VMI) is important in children's development because it is associated with the performance of many functional skills. Deficits in VMI have been linked to difficulties in academic performance and functional tasks. Clinical assessment experience of occupational therapists in Singapore suggested t...
25,219,320
[ -0.06290652, 0.06377304, -0.1085576, -0.1881929, 0.2403527, -0.3187929, -0.570505, 0.0307324, 0.1077816, -0.4441735, 0.4088414, 0.05301625, -0.6272518, -0.5642329, -0.4105802, 0.05228041, -0.07526908, 0.1031942, -0.4754927, -0.1202029, -0.05983112, 0.3699821, 0.01817277, ...
Pharmacokinetic interactions between topiramate and pioglitazone and metformin.
To investigate potential drug-drug interactions between topiramate and metformin and pioglitazone at steady state. Two open-label studies were performed in healthy adult men and women. In Study 1, eligible participants were given metformin alone for 3 days (500 mg twice daily [BID]) followed by concomitant metformin an...
25,219,351
[ -0.08095548, 0.3132619, -0.190703, -0.08852106, 0.1449633, -0.230107, -0.5224744, 0.3335457, 0.04518878, -0.3779983, 0.1683577, 0.2009577, 0.01593982, 0.057499, -0.3391303, -0.3170426, -0.3909899, 0.3545524, -0.2073931, 0.3278711, -0.0166476, 0.1921376, -0.1578549, -0.2...
First use of the WAVE™ disposable rocking bioreactor for enhanced bioproduct synthesis by N2 -fixing cyanobacteria.
WAVE™ rocking disposable bioreactors have been successfully utilized for bioproduct development from bacteria, yeast, microalgae, and animal and plant cells but not from cyanobacteria so far. N2 -fixing cyanobacteria represent a prolific bioproducts source with reduced cultivation costs. In this study, 1 L cultures of ...
25,219,374
[ -0.1648057, -0.1145195, -0.1106113, -0.2337691, 0.01679202, -0.3354061, 0.09858602, 0.1054589, 0.2548017, -0.277636, -0.1134222, -0.1882149, -0.323351, -0.402719, -0.4945424, 0.1403608, -0.3386338, -0.2359344, -0.09391692, 0.1263945, 0.4699842, 0.4797748, -0.39979, 0.06...
Physician payment methods: a focus on quality and cost control.
With rising health care costs, governments must develop innovative methods to deliver efficient and equitable health care services. With physician remuneration being the third largest health care expense, the design of remuneration methods is a priority in health care policy. Otolaryngology-Head and Neck surgeons shoul...
25,219,382
[ -0.115512, 0.0140429, -0.2084547, 0.1301436, -0.1747866, -0.2381807, 0.04918011, 0.1980522, -0.056011, 0.1895795, 0.04134673, -0.1601128, -0.2970552, -0.3991185, -0.2032751, -0.1019508, 0.1083538, -0.00159179, -0.3084408, -0.2048762, 0.242639, -0.06896481, -0.02466151, ...
Effect of breeding activity on the microflora of the external genitalia and in the semen of stallions, and the relationship between micro-organisms on the skin and on the external genitalia.
A possible role of breeding activities in the composition of the microbial population in stallions' external genitalia (EG) and the relationship between micro-organisms colonizing the skin of the abdomen and the ones colonizing the EG have not been studied. In experiment 1, EG microbiological samples were collected fro...
25,219,398
[ -0.0251692, 0.2015862, -0.01347273, 0.07265517, 0.08590793, -0.1115679, -0.2714204, -0.1164519, -0.001533911, -0.3609602, 0.01750032, -0.1918386, -0.06945619, 0.002068525, -0.4952234, 0.3147964, -0.2706276, -0.04321001, 0.09493928, 0.006664594, 0.04531953, 0.4766391, -0.1...
Anti-transforming growth factor β-induced protein antibody ameliorates vascular barrier dysfunction and improves survival in sepsis.
Sepsis is a systemic inflammatory response syndrome resulting from a microbial infection. Transforming growth factor β-induced protein (TGFBIp) is an extracellular matrix protein expressed by human endothelial cells and platelets that induces sepsis through interaction with integrin αvβ5. The aim of this study was to i...
25,219,400
[ 0.1471346, -0.1697087, -0.1562829, -0.02175508, -0.0001568408, 0.1575804, 0.04808474, 0.1331071, -0.07628644, 0.2104068, -0.01338338, -0.02159273, -0.4297611, -0.2743955, -0.1185637, -0.1371297, -0.6004759, -0.01212867, -0.2447343, 0.4883526, 0.09018695, 0.1262121, 0.1088...
Blood pressure reference values for European non-overweight school children: the IDEFICS study.
To provide oscillometric blood pressure (BP) reference values in European non-overweight school children. Cross-sectional analysis from the IDEFICS study (www.ideficsstudy.eu) database. Standardised BP and anthropometric measures were obtained from children aged 2 to 10.9 years, participating in the 2007-2008 and 2009-...
25,219,411
[ -0.09088196, -0.1185532, -0.2850922, -0.07329633, 0.2376068, -0.2297719, -0.08608092, 0.001499039, 0.09094548, -0.0114074, 0.01155303, 0.01365312, -0.2120989, -0.2277297, -0.7526893, -0.09911708, -0.2277522, 0.2270335, -0.5186808, 0.1074222, 0.01579864, -0.1659944, -0.253...
Competitive direct vs. indirect photochromism dynamics of constrained inverse dithienylethene molecules.
State-of-the-art experimental and theoretical tools were used to investigate the gas-phase relaxation dynamics of various photoexcited photochromic dithienylethene molecules in situations where several relaxation channels are simultaneously at play. Unconstrained and constrained dynamics were addressed by considering u...
25,219,416
[ -0.180911, -0.02406234, 0.007541643, 0.01142858, 0.3436979, -0.3548721, -0.2845288, 0.03838305, 0.2569327, 0.02433554, -0.113739, 0.04038727, 0.08549666, 0.1864407, -0.379318, -0.2986177, -0.6075196, 0.1182198, -0.02925219, -0.03295154, 0.1310697, 0.0371757, -0.2424224, ...
How does an undergraduate pain course influence future physicians' awareness of chronic pain concepts? A comparative study.
Pain is one of the most undertreated medical complaints, with barriers to effective pain management lying in poor education of health professionals and misconceptions regarding patients in pain. The aim of this study was to assess whether an elective undergraduate course on chronic pain offered in Greek medical schools...
25,219,419
[ 0.02581487, 0.2427589, -0.1219086, 0.2177853, -0.08768929, -0.2819912, 0.03320391, -0.1117016, -0.09445138, 0.09973715, -0.09990746, -0.09241317, 0.02408388, 0.01071701, -0.4414021, -0.1167816, 0.0002718183, 0.2707522, 0.2298104, -0.06984597, 0.1413082, 0.008571392, 0.006...
The STRIDE weight loss and lifestyle intervention for individuals taking antipsychotic medications: a randomized trial.
The STRIDE study assessed whether a lifestyle intervention, tailored for individuals with serious mental illnesses, reduced weight and diabetes risk. The authors hypothesized that the STRIDE intervention would be more effective than usual care in reducing weight and improving glucose metabolism. The study design was a ...
25,219,423
[ -0.1098948, 0.2327192, -0.2144675, -0.2678938, -0.05791583, -0.4223989, -0.07810146, -0.09165942, 0.2168794, -0.0846545, -0.01830242, 0.106925, -0.1657663, -0.1315613, -0.1220146, 0.1512677, -0.5435742, 0.1029864, -0.1093488, -0.1250249, -0.3802567, 0.272309, -0.09888723,...
[Temporal-spatial scan clustering analysis on hand-foot-mouth disease in Zhejiang province, 2008-2013].
To understand the temporal-spatial distribution of hand-foot-mouth disease in Zhejiang province, from May 2008 to June 2013. The cases number and incidence data of hand-foot-mouth disease from May 2008 to June 2013 for all the counties(cities, districts) in Zhejiang province were collected from China Information System...
25,219,431
[ -0.05021271, -0.02879324, 0.1892393, 0.1220755, -0.04537386, -0.2252677, -0.1354363, 0.01355094, -0.1411957, -0.1205933, -0.09847265, -0.2402767, 0.2918025, 0.1716518, 0.1193462, -0.2971396, -0.2763156, 0.3860738, 0.04680963, -0.08228897, 0.07819732, 0.6614962, -0.1115645...
[Analysis of death causes among infants in Guangzhou from 2010 to 2013].
To analyze the main death causes among infants in Guangzhou in 2010-2013 and to provide an objective and scientific basis for risk communication of public health emergencies in the future. Descriptive epidemiological method was used to analyze the death causes among infants reported in Guangzhou from the National Death...
25,219,438
[ -0.4954699, 0.02747061, 0.3472647, 0.2019244, 0.3197714, -0.2248417, 0.01752916, -0.1254576, -0.1200957, 0.1559558, 0.09523563, 0.2431321, -0.03707203, 0.108094, -0.04111452, -0.2268679, -0.07558447, 0.07057, 0.04823935, 0.03657819, 0.3558054, 0.3396114, -0.1725364, 0.0...
[Analysis of trends and characteristics of mortality of ischemic heart disease over the age of 35 years old in China, 2004-2011].
To analyze the features of distribution and variation trends of mortality of ischemic heart disease over the age of 35 years old in China, 2004-2011. A total of 493 274 cases were recruited in the study, the mortality data of the ischemic heart diseases were collected from the national disease surveillance point (DSP) ...
25,219,440
[ -0.0763166, -0.4958168, -0.02617735, 0.1956732, -0.1224206, -0.2274332, 0.0618596, -0.01605864, -0.06991276, 0.1142865, 0.1402513, 0.4765179, -0.015171, 0.229793, 0.05867009, -0.1890434, -0.1101605, 0.2078726, 0.03044113, 0.01969206, 0.07137112, 0.567698, -0.2707874, 0....
[Application of multi-level model in study of relationship between soil cadmium contamination and people's urinary cadmium level].
Based on the characteristics of hierarchical data, a multilevel model was used to analysis possible influencing factors of urinary cadmium levels in one county population, and to discuss the advantages of multilevel model for processing hierarchical data in practical problems. In May 2013, 1 460 participants aged 20 an...
25,219,442
[ 0.06607171, 0.360828, -0.01388066, 0.1572915, -0.07405794, -0.412485, -0.5093153, -0.02321776, -0.01909934, -0.006170902, 0.0125276, 0.1307849, 0.06385057, 0.1956632, -0.3882325, -0.07221694, -0.2428245, 0.03289144, 0.1145576, 0.07355863, -0.03293459, 0.456383, -0.2745891...
High frequency of posterior and combined shoulder instability in young active patients.
The purpose of this study was to describe the epidemiology and demographics of surgically treated shoulder instability stratified by direction. We hypothesized that there would be an increased frequency of posterior and combined shoulder instability in our population compared with published literature. Secondarily, we ...
25,219,471
[ -0.2771977, -0.003798456, -0.04078842, -0.4523363, -0.2207245, -0.2348429, -0.1958276, 0.1092666, 0.1892157, -0.04292662, 0.169501, -0.1752695, 0.05617169, -0.4418772, 0.1673775, -0.2878144, 0.07009024, 0.2694731, -0.05564935, 0.02619716, 0.2370247, -0.0820798, -0.1603829...
Sensitization of ethanol-induced place preference as a result of up-regulation of type 1 inositol 1,4,5-trisphosphate receptors in mouse nucleus accumbens.
This study involved mice that received 4 days of ethanol (EtOH) vapor inhalation and then were assessed for type 1 inositol 1,4,5-trisphosphate receptor (IP3 Rs-1) expression and the development of EtOH-induced place preference at various time points in withdrawal. IP3 R-1 protein was found to be significantly increase...
25,219,476
[ -0.05764472, -0.2322311, -0.3324786, 0.1226379, 0.1988092, 0.05263212, -0.1225474, -0.2723261, -0.0256438, 0.3373542, 0.06373511, -0.06275957, -0.2927725, 0.2907571, -0.2885045, -0.2146297, -0.1227002, 0.1732298, 0.3095025, 0.07789853, -0.1408704, 0.3940531, 0.251414, -...
Relaparotomy in colorectal cancer surgery--do any factors influence the risk of mortality? A case controlled study.
Identification of the incidence of relaparotomy after operations for colorectal cancer and finding out factors influencing the incidence of relaparotomy and risk of mortality. In the period from 2008 to 2012 the group of patients electively operated on for colorectal cancer was analysed. The database of the surgical de...
25,219,479
[ 0.1081027, -0.1761741, -0.2984606, -0.0577973, -0.06895047, -0.194636, 0.2842209, -0.268552, -0.02798457, -0.01900034, 0.1260701, 0.01497398, 0.1866522, -0.3283506, -0.1729527, -0.3817249, -0.1329151, 0.1489327, 0.1115378, -0.2095967, 0.2497834, 0.3672771, 0.07130156, 0...
An electric-field assisted growth control methodology for integrating ZnO nanorods with microstructures.
The growth control of ZnO nanorods bridging over two microelectrodes in a three-electrode structure (the top cathode and anode, and the bottom gate) was realized using a wet chemical method with the assistance of an electric field generated by applying AC sine wave power on the top electrodes and a DC voltage on the bo...
25,219,487
[ 0.08438729, 0.06141934, 0.1486637, 0.05878658, 0.04743718, -0.08057728, -0.2766393, 0.05338418, -0.1452708, -0.02120506, -0.258347, -0.2446, -0.1310624, 0.2323631, -0.6834779, 0.07877075, -0.1531575, -0.06714658, -0.119154, -0.0207691, 0.324442, 0.05015431, -0.2303018, ...
The serotonin transporter genotype modulates the relationship between early stress and adult suicidality in bipolar disorder.
Bipolar disorder (BD) is associated with a higher risk of suicide and with worse early life stress. A serotonin (5-hydroxytryptamine; 5-HT) transporter-linked polymorphic region (5-HTTLPR) has been shown to influence the relationship between stress and the risk of attempting suicide in the general population, but has n...
25,219,494
[ 0.03829091, -0.2610246, -0.09686169, 0.02132223, 0.1271041, -0.4269128, -0.1061823, -0.6017488, -0.1813087, 0.1960218, -0.1183084, -0.03715584, -0.2194091, 0.2977658, -0.1612284, -0.3196595, -0.1899072, 0.152004, 0.2785497, -0.06914958, 0.1319022, 0.3998147, -0.3225486, ...
WT1 expression in endocrine mucin-producing sweat gland carcinoma: a study of 13 cases.
Endocrine mucin-producing sweat gland carcinoma (EMPSGC), a low-grade sweat gland carcinoma with a predilection for the eyelids, often shows areas of benign eccrine cysts, atypical intracystic proliferation and associated mucinous carcinoma, suggesting tumor progression. Wilms tumor 1 (WT1) protein, a transcription fac...
25,219,513
[ -0.01296792, -0.312316, -0.5448749, -0.4830193, -0.08309281, -0.1694659, -0.02960903, -0.2244332, 0.1172587, 0.1762334, -0.123833, 0.07681523, -0.1156928, -0.2347142, -0.4593124, 0.01011721, -0.4407469, -0.0850454, 0.1417687, -0.5324734, 0.4260244, -0.2030297, -0.02296762...
Origin of high photoconductive gain in fully transparent heterojunction nanocrystalline oxide image sensors and interconnects.
A technique for invisible image capture using a photosensor array based on transparent conducting oxide semiconductor thin-film transistors and transparent interconnection technologies is presented. A transparent conducting layer is employed for the sensor electrodes as well as interconnection in the array, providing a...
25,219,518
[ -0.06855954, -0.09568287, 0.1279974, 0.0483085, 0.01106943, -0.2209637, -0.6392744, 0.05766082, 0.09022081, -0.1060806, -0.02970723, -0.09582051, -0.04044478, -0.1173928, -0.508359, -0.2337733, -0.5250618, 0.04495299, -0.1441438, -0.07841296, 0.1534407, 0.08029103, -0.282...
Deep sequencing of the ancestral tobacco species Nicotiana tomentosiformis reveals multiple T-DNA inserts and a complex evolutionary history of natural transformation in the genus Nicotiana.
Nicotiana species carry cellular T-DNA sequences (cT-DNAs), acquired by Agrobacterium-mediated transformation. We characterized the cT-DNA sequences of the ancestral Nicotiana tabacum species Nicotiana tomentosiformis by deep sequencing. N. tomentosiformis contains four cT-DNA inserts derived from different Agrobacteri...
25,219,519
[ -0.04896928, -0.1251733, 0.05331365, 0.01697988, 0.09673479, -0.04099123, -0.2485848, -0.06545618, 0.3501522, -0.06436908, 0.1748692, 0.08699588, 0.03431349, 0.1103077, -0.8747315, 0.3229732, -0.6221453, 0.08165114, 0.5332531, -0.1821968, 0.3088199, 0.359056, -0.4386335, ...
Characterization of the starvation-induced chitinase CfcA and α-1,3-glucanase AgnB of Aspergillus niger.
The common saprophyte Aspergillus niger may experience carbon starvation in nature as well as during industrial fermentations. Starvation survival strategies, such as conidiation or the formation of exploratory hyphae, require energy and building blocks, which may be supplied by autolysis. Glycoside hydrolases are key ...
25,219,534
[ -0.1337154, -0.1091942, 0.006565057, -0.06269737, 0.1281753, -0.1607462, -0.07831782, -0.04242026, 0.2124572, -0.01143026, -0.06527828, -0.005031178, -0.2426155, 0.08953241, -0.1153812, 0.1781149, -0.5950141, -0.07834771, 0.03475714, -0.07425629, 0.5247756, 0.573081, -0.3...
[Enhancement of gastric cancer MKN28 cell line radiosensitivity induced by β-elemene].
To study radiation-enhancing effects on human gastric cancer MKN28 cell line and underlying mechanisms of β-elemene. Inhibition of MKN28 cell proliferation at different concentrations of β-elemene was assessed using the methyl thiazolyl blue colorimetric method (MTT method), with calculation of IC50 value and choice of...
25,219,560
[ -0.1745202, 0.05217352, -0.05098056, -0.2777302, 0.3553854, 0.1308767, -0.1573898, 0.2739216, 0.4733316, 0.07082321, 0.1069243, 0.5516273, -0.1493295, 0.05886631, -0.2137002, -0.1201652, -0.3560072, 0.2175569, 0.1815384, 0.7391351, 0.4768808, 0.1010398, -0.1041205, 0.18...
Relationships between obesity management and depression management in a university-based family medicine center.
The purpose of this study is to describe and examine relationships among sociodemographics, obesity, and depression management in Appalachian adults. This study was conducted in a primary care center and used a cross-sectional, quantitative, nonexperimental descriptive, and predictive design. Data were obtained from a ...
25,219,571
[ -0.04852247, 0.2025571, -0.143906, -0.02924301, 0.1220899, -0.2403956, -0.3146498, -0.04838918, -0.04425018, -0.02919198, -0.05521928, 0.01369358, 0.09873083, -0.1619228, -0.6194479, 0.1517408, 0.02025581, 0.3642676, -0.07098804, -0.02382882, -0.5669461, -0.1328332, -0.21...
Shape analysis of the proximal humerus in orthograde and semi-orthograde primates: correlates of suspensory behavior.
"Suspensory locomotion" is an expression that encompasses a series of specialized forms of locomotion that mainly orthograde primates use to achieve below-branch traveling. It implies a number of features in the entire body associated with the use of the forelimb in overhead positions. The glenohumeral joint is one of ...
25,219,580
[ 0.06625905, 0.18638, -0.1178754, -0.144363, -0.5362169, -0.4605685, -0.5121511, -0.2408003, 0.0891103, -0.1953584, -0.01268585, -0.417646, 0.00540899, -0.06000209, -0.4664343, 0.01160657, -0.4252158, 0.1507075, -0.1347503, 0.4845423, 0.2861281, 0.112411, 0.08310229, -0....
A genetic analysis of the validity of the Hypomanic Personality Scale.
Studies of mania risk have increasingly relied on measures of subsyndromal tendencies to experience manic symptoms. The measures of mania risk employed in those studies have been shown to predict manic onset, to show familial associations, and to demonstrate expected correlations with psychosocial variables related to ...
25,219,588
[ -0.1286677, -0.406146, -0.1742612, -0.11134, 0.1846054, -0.2844279, -0.03178684, -0.0502157, 0.1260774, -0.280631, 0.1503759, -0.01039702, -0.03040513, -0.1646663, -0.1839625, -0.04204672, -0.7365206, 0.4318627, 0.3155273, -0.06658987, 0.1083075, 0.07275414, 0.01788243, ...
UFLC/MS-IT-TOF guided isolation of anti-HBV active chlorogenic acid analogues from Artemisia capillaris as a traditional Chinese herb for the treatment of hepatitis.
Hepatitis B induced by HBV is a serious health problem. Artemisia capillaris (Yin-Chen) has long been used to treat hepatitis in traditional Chinese medicine. Coumarins, flavonoids and organic acids were revealed as its hepatoprotective and choleretic components, but its anti-HBV active components remain unknown. This ...
25,219,603
[ -0.1299798, 0.2907057, 0.122955, 0.3503527, 0.384513, 0.2745481, -0.3338223, 0.1494446, 0.4044014, 0.1320648, 0.2229915, 0.151639, -0.1195662, 0.05887255, -0.6000352, -0.02569802, -0.3975835, 0.4307418, -0.1220653, 0.4013387, 0.06848754, 0.04514485, -0.4318143, -0.37174...
Factors which can influence the quality related to cell viability of the umbilical cord blood units.
Cell viability is an important indicator for the quality of umbilical cord blood (UCB) units that can influence the transplant final outcome. Thus, it is particularly important to identify the factors that may affect the cell quality during the banking process. The present study is a first attempt to correlate the impa...
25,219,638
[ 0.03560248, -0.02621163, -0.1476658, 0.05506884, 0.2289432, -0.2010493, 0.04501625, -0.03752524, 0.01606845, 0.3255298, -0.06648127, 0.2917581, -0.3985374, -0.2326792, -0.3862148, -0.2252106, 0.3336422, -0.07719401, -0.3148095, 0.2959373, 0.5637404, 0.2708669, -0.1632984,...
Comparison of double dose plateletpheresis on the Fenwal Amicus, Fresenius COM.TEC and Trima Accel cell separators.
A variety of apheresis instruments are now available on the market for double dose plateletpheresis. We compared three apheresis devices (Fenwal Amicus, Fresenius COM.TEC and Trima Accel) with regard to processing time, platelet (PLT) yield, collection efficiency (CE) and collection rate (CR). The single-needle or doub...
25,219,639
[ -0.215257, 0.1432994, -0.1280099, -0.121856, -0.0006646699, -0.4902785, -0.1870601, 0.09663243, -0.04385463, 0.1178641, -0.2180575, 0.05539012, 0.2401066, -0.2252574, -0.294393, -0.08365464, -0.08044494, -0.331883, -0.2877015, 0.2891699, 0.08485498, -0.06749129, -0.280564...
Exoming into rare skin disease: EGFR deficiency.
Dermatologists are frequently asked to see patients with pustular eruptions caused by EGFR mAbs or tyrosine kinase inhibitors. In this issue, Campbell et al. describe an infant with severely inflammed skin and bowel and lung disease caused by a homozygous mutation in the EGFR gene. This commentary discusses the power o...
25,219,648
[ 0.187612, -0.276308, -0.04062976, -0.173731, 0.02119194, 0.138128, -0.1842158, -0.09328476, -0.1944887, -0.1576788, 0.3161975, 0.2924379, -0.1032301, -0.006377984, 0.005106048, 0.1151509, -0.1212878, 0.01373908, -0.01463145, -0.2574112, 0.00003829113, 0.4671598, -0.128374...
WISP1: Clinical insights for a proliferative and restorative member of the CCN family.
As a proliferative and restorative entity, Wnt1 inducible signaling pathway protein 1 (WISP1) is emerging as a novel target for a number of therapeutic strategies that are relevant for disorders such as traumatic injury, neurodegeneration, musculoskeletal disorders, cardiovascular disease, pulmonary compromise, and con...
25,219,658
[ -0.3407936, -0.1461008, 0.1908737, -0.6683222, -0.1152133, -0.4533045, -0.01332259, 0.1904937, -0.04157589, 0.1356698, 0.08667726, 0.07180604, -0.1173657, -0.05388337, -0.2268934, 0.167362, -0.2643225, 0.1800131, 0.03860162, -0.02316082, 0.08128171, 0.1181984, -0.2187717,...
Biochemical markers of joint tissue damage increase shortly after a joint bleed; an explorative human and canine in vivo study.
Evaluation whether biomarkers of joint damage are sensitive to change shortly after a joint bleed in hemophilia patients and in a canine model of blood-induced joint damage. Blood and urine samples were collected from 10 hemophilia patients after they reported a joint bleed: within 2 days, after 3-5 days, and 12-14 day...
25,219,667
[ -0.04625666, 0.1844486, -0.1133499, -0.3651811, -0.2416177, -0.2918721, -0.08632263, 0.389032, 0.1025306, -0.1926583, 0.05508838, -0.01111105, 0.04581113, -0.6890088, -0.07261515, 0.07138802, 0.1544074, -0.0016922, 0.003819459, 0.01959521, -0.0703496, 0.2783321, -0.091253...
Radiosensitivity in patients suffering from chronic kidney disease.
Patients suffering from chronic kidney disease (CKD) exhibit a high incidence of cancer, as well as high levels of genetic damage. We hypothesized that these patients show genomic instability detected as an increased chromosomal radiosensitivity in front of the genetic damage induced by ionizing radiation. The backgrou...
25,219,678
[ 0.008183192, -0.2960962, -0.1507323, 0.1105608, -0.009439189, -0.1524934, 0.06571551, -0.05198064, 0.02279013, 0.225315, 0.1238892, 0.1436105, 0.004484423, 0.3762449, -0.3627087, -0.411164, -0.1517116, 0.1633153, 0.156932, 0.1330204, 0.08826324, 0.1881163, 0.1344984, -0...
Variants of the melanocortin-1 receptor: do they matter clinically?
The melanocortin 1 receptor (MC1R) gene encodes for a seven-pass transmembrane receptor primarily expressed on melanocytes and melanoma cells. Single nucleotide polymorphisms (SNPs, also termed variants) in MC1R frequently cause red hair, fair skin and are associated with melanoma and keratinocyte-derived skin cancer d...
25,219,681
[ -0.09031668, -0.598053, -0.1662008, -0.2764503, 0.1956875, -0.2635705, -0.252322, -0.04068509, 0.3070984, 0.2677188, 0.1469951, 0.2887811, -0.128663, -0.1081718, -0.3874616, -0.1645737, -0.150093, -0.03892605, 0.2098665, -0.05300046, 0.2646386, 0.3758988, -0.3490916, 0....
[Augmentation strategies in patients with schizophrenia who show partial response to clozapine treatment].
A significant proportion of patients with schizophrenia receiving clozapine remain with partial response. In this group of patients findings regarding addition of various psychotropics to ongoing clozapine treatment for augmentation are controversial. In this review, literature regarding the efficacy and safety of adju...
25,219,694
[ 0.02634205, 0.2526442, -0.02505999, -0.3763453, 0.1636107, -0.4251552, -0.3612242, -0.05912421, 0.05517421, -0.0735992, -0.08882381, 0.1391979, -0.02237278, 0.4208871, 0.03174437, -0.2404341, -0.5251052, 0.1612915, 0.0720041, 0.2353387, -0.001201256, -0.02738114, -0.18398...
Impact of dynamic transrectal ultrasonography on pelvic organ prolapse.
We developed a new method to evaluate pelvic organ prolapse dynamically in patients in supine and standing positions using transrectal ultrasonography. We visualized the descent and prolapse of pelvic organs in real time using dynamic transrectal ultrasonography. The dynamic transrectal ultrasonography findings were co...
25,219,698
[ 0.07774931, -0.1178037, 0.01155929, -0.2043643, 0.4266509, -0.4687341, -0.08659959, 0.1251402, 0.08371983, -0.1406572, 0.1272366, -0.2465039, -0.2234055, -0.09303973, -0.05241583, 0.05310506, -0.6160203, 0.2133957, -0.2881033, -0.2977161, -0.1829066, 0.4630835, -0.0209566...
Contemporary surgical trends in the management of upper tract calculi.
Upper tract nephrolithiasis is a common surgical condition that is treated with multiple surgical techniques, including shock wave lithotripsy, ureteroscopy and percutaneous nephrolithotomy. We analyzed case logs submitted to the ABU by candidates for initial certification and recertification to help elucidate the tren...
25,219,700
[ 0.07594305, 0.1491305, -0.1594778, -0.09120212, 0.1598891, -0.4925634, -0.3628819, -0.0185922, 0.134809, 0.3588564, 0.35822, 0.2045474, -0.0772289, -0.2518402, -0.2749736, 0.01792509, 0.1896942, -0.1638658, 0.09550607, -0.4516121, 0.06216341, 0.008536887, -0.4135413, 0....
A European multicenter randomized noninferiority trial comparing 180 W GreenLight XPS laser vaporization and transurethral resection of the prostate for the treatment of benign prostatic obstruction: 12-month results of the GOLIATH study.
We present the 1-year results of the GOLIATH prospective randomized controlled trial comparing transurethral resection of the prostate to GreenLight XPS for the treatment of men with nonneurogenic lower urinary tract symptoms due to prostate enlargement. The updated results at 1 year show that transurethral resection o...
25,219,699
[ 0.03134073, -0.01656828, -0.2805777, -0.08503503, -0.4970319, -0.4251307, -0.06457129, 0.03762633, 0.1451077, -0.2561108, 0.04020589, 0.3711101, -0.1666531, -0.05959263, -0.3297615, -0.2418163, -0.1309221, 0.1389546, 0.01753084, -0.3458275, 0.09523493, 0.6951231, -0.17165...
Development of haemostatic decontaminants for the treatment of wounds contaminated with chemical warfare agents. 2: evaluation of in vitro topical decontamination efficacy using undamaged skin.
The risk of penetrating, traumatic injury occurring in a chemically contaminated environment cannot be discounted. Should a traumatic injury be contaminated with a chemical warfare (CW) agent, it is likely that standard haemostatic treatment options would be complicated by the need to decontaminate the wound milieu. Th...
25,219,755
[ -0.2404438, -0.2008006, -0.09088225, -0.2393646, 0.2399103, 0.117684, -0.4652662, -0.1265819, 0.05273891, 0.1605826, -0.0919918, 0.05737179, 0.2878233, 0.008542699, 0.005406013, -0.03088227, -0.2850023, -0.2069632, -0.1046937, 0.2072372, 0.285849, 0.2226397, -0.04652748, ...
Microcomputed tomographic analysis of human condyles in unilateral condylar hyperplasia: increased cortical porosity and trabecular bone volume fraction with reduced mineralisation.
Unilateral condylar hyperplasia or hyperactivity is a disorder of growth that affects the mandible, and our aim was to visualise the 3-dimensional bony microstructure of resected mandibular condyles of affected patients. We prospectively studied 17 patients with a clinical presentation of progressive mandibular asymmet...
25,219,775
[ -0.2831824, 0.08506025, -0.06715691, 0.07981129, -0.08197496, -0.3688905, -0.2902824, -0.1276172, 0.05687695, -0.3139974, 0.01889052, -0.1049389, -0.5474404, -0.2535338, -0.3885228, -0.1666361, -0.2352596, 0.1680991, -0.1254371, -0.01059277, -0.009696835, 0.1390443, -0.08...
Reliability and validity of measurements of facial swelling with a stereophotogrammetry optical three-dimensional scanner.
Volume changes in facial morphology can be assessed using the 3dMD DSP400 stereo-optical 3-dimensional scanner, which uses visible light and has a short scanning time. Its reliability and validity have not to our knowledge been investigated for the assessment of facial swelling. Our aim therefore was to assess them for...
25,219,776
[ -0.08211573, -0.1416882, -0.1928569, -0.09740406, 0.1972656, -0.2058773, 0.1179916, -0.0218939, 0.442051, -0.5359722, 0.1677127, -0.4883338, 0.02834936, -0.4000613, -0.4994386, -0.03012593, -0.2872667, 0.2264009, -0.2415988, -0.1949271, 0.004795029, 0.1145146, -0.1362988,...
Subjective-objective sleep discrepancy among older adults: associations with insomnia diagnosis and insomnia treatment.
Discrepancy between subjective and objective measures of sleep is associated with insomnia and increasing age. Cognitive behavioural therapy for insomnia improves sleep quality and decreases subjective-objective sleep discrepancy. This study describes differences between older adults with insomnia and controls in sleep...
25,219,802
[ 0.1175103, 0.3448344, -0.1401281, -0.1306426, 0.2492314, -0.1914361, -0.1124304, -0.03550842, 0.08731028, -0.1257788, 0.2829854, 0.05600937, -0.2660468, -0.4569692, -0.3526965, -0.04330705, -0.3223408, 0.395, -0.1322496, -0.09396344, -0.280489, 0.1924464, 0.03287483, -0...
The dual binding site of angiogenin and its inhibition mechanism: the crystal structure of the rat angiogenin-heparin complex.
The heparin complex of rat angiogenin revealed that a heparin strand is fitted into a positively charged groove formed by the dual binding site of rat angiogenin, suggesting that cell adhesion to angiogenin is facilitated by its interaction with substrates on the cell surface and can be inhibited by heparin.
25,219,815
[ -0.005794869, 0.08931811, -0.3426944, 0.03081439, 0.1604552, 0.05350845, -0.2477876, 0.02396945, 0.1171982, 0.1988252, 0.01581908, 0.1039399, -0.1046755, -0.3054017, -0.2104777, -0.03284442, -0.1949436, 0.0394034, -0.02986735, 0.06950875, 0.1091835, 0.1600123, -0.1395686,...
Combination therapy with retinaldehyde (0.1%) glycolic acid (6%) and efectiose (0.1%) in mild to moderate acne vulgaris during the period of sun exposure--efficacy and skin tolerability.
Acne vulgaris is the most common disease of the adolescence age (70-94%). Main topical treatments for acne vulgaris are retinoids, benzoyl peroxide and antibiotics in mono or combination therapy. Topical retinoids, some antibiotics and antiseptics although effective on acne lesions, can due photosensitivity or make the...
25,219,827
[ 0.09205192, -0.3028167, -0.1945841, 0.1223967, 0.02035251, -0.2933467, 0.05328519, -0.2971978, -0.1223026, -0.08061132, -0.03385334, 0.2717903, -0.02294712, -0.1946383, 0.02062863, -0.1976272, -0.2419962, 0.449126, -0.08825118, 0.1600795, 0.2695978, 0.07322099, -0.0081657...
Expression of rat oligodendrocyte transcription factor 2 in COS-7 cells following its eukaryotic expression vector construction.
The basic HLH transcription factor Olig is a key regulator for differentiating the oligodendrocyte lineage cells during development. Oligodendrocyte transcription factor 2 (Olig2) plays a crucial role in differentiating the oligodendrocytes in the spinal cord. We aimed to construct and investigate the eukaryotic expres...
25,219,831
[ 0.3508164, -0.1342058, -0.1195037, 0.1320039, 0.07395315, 0.09236196, 0.1049262, 0.1360707, 0.02033917, -0.3244303, 0.04620807, 0.2850481, 0.5425546, 0.4423797, -0.507105, 0.01628562, -0.3289658, -0.281719, -0.1382933, 0.3974377, 0.3114024, 0.3134654, 0.101634, 0.112604...
Minimally invasive (sinus tarsi) approach for open reduction and internal fixation of intra-articular calcaneus fractures in children: surgical technique and case report of two patients.
Calcaneus fractures in children differ from those in adults. Most calcaneus fractures in children can be managed nonoperatively, with good long-term results expected. The width and height of the calcaneus can remodel with time in children. Recently, there has been a trend toward operative treatment of displaced intra-a...
25,219,845
[ -0.5160416, 0.3860724, 0.02045099, -0.03164112, -0.02225309, -0.15535, -0.315834, 0.191301, 0.2563877, 0.001258558, 0.07108962, -0.4416226, -0.3741917, -0.2636346, -0.2028172, -0.2817765, -0.09331674, 0.09071321, -0.09293003, -0.06611128, -0.1320102, -0.1578512, -0.185466...
Asian monsoons in a late Eocene greenhouse world.
The strong present-day Asian monsoons are thought to have originated between 25 and 22 million years (Myr) ago, driven by Tibetan-Himalayan uplift. However, the existence of older Asian monsoons and their response to enhanced greenhouse conditions such as those in the Eocene period (55-34 Myr ago) are unknown because o...
25,219,854
[ 0.00263514, 0.1350054, -0.06751259, 0.1824336, -0.09354667, 0.007564824, -0.6113229, -0.0003946656, 0.2180602, -0.3678766, -0.2020852, 0.01312401, 0.1102278, 0.0536244, -0.537178, -0.0960104, -0.2189086, 0.2439205, -0.07750266, 0.09711398, 0.1548093, 0.3749469, -0.1943033...
Planar bioadhesive microdevices: a new technology for oral drug delivery.
The oral route is the most convenient and least expensive route of drug administration. Yet, it is accompanied by many physiological barriers to drug uptake including low stomach pH, intestinal enzymes and transporters, mucosal barriers, and high intestinal fluid shear. While many drug delivery systems have been develo...
25,219,863
[ -0.1490238, -0.08662943, 0.005373274, -0.01415798, 0.1704432, -0.1833437, -0.03738217, 0.2040765, 0.02628269, 0.1208528, 0.213603, -0.4420385, -0.02515212, -0.004209223, -0.5284275, -0.02570572, -0.5272354, 0.0937747, -0.01972, -0.09391795, 0.1597608, 0.02713086, -0.21463...
Design of bioartificial pancreas with functional micro/nano-based encapsulation of islets.
Type I diabetes mellitus (TIDM), a devastating health issue in all over the world, has been treated by successful transplantation of insulin secreting pancreatic islets. However, serious limitations such as the requirement of immunosuppressive drugs for recipient patients, side effects as a result of long-term use of d...
25,219,869
[ -0.3119263, -0.2182051, -0.1890924, 0.2600252, -0.1487216, -0.085578, -0.3814272, 0.3702982, 0.189978, -0.1579993, 0.210219, -0.4525801, 0.1087006, -0.1216, -0.3819841, -0.1408346, -0.1652936, -0.0554828, -0.1221046, -0.2889906, -0.02531881, 0.1965362, 0.08942997, -0.06...
Clinical treatment of cutaneous leishmaniasis in dogs with furazolidone and domperidone.
Cutaneous leishmaniasis (CL) is a zoonosis and a public health problem in countries of subtropical America. The aim of this study was to investigate the efficacy of furazolidone and domperidone treatment of dogs naturally infected with Leishmania (Viannia) braziliensis. Infection was confirmed by PCR and parasite cultu...
25,219,877
[ -0.08030463, -0.282635, 0.1055458, -0.4434615, 0.2807784, -0.1498056, -0.378418, -0.3291245, 0.2053044, -0.1886298, 0.005076964, -0.163396, 0.1090234, 0.03811496, -0.3302116, -0.2566209, -0.03363217, -0.1028152, -0.1197278, -0.0808794, -0.1108156, 0.03116187, -0.163277, ...
Maternal kin bias in affiliative behavior among wild adult female blue monkeys.
Kin-biased cooperative and affiliative behavior is widespread in social mammals and is expected to increase fitness. However, despite evolutionary benefits of cooperating with relatives, demographic circumstances may influence the strength of kin bias. We studied the relationship between maternal kinship and affiliativ...
25,219,933
[ 0.1471004, 0.3411752, -0.3121247, -0.2376044, 0.2498759, -0.2678605, -0.06278662, -0.2250964, -0.02381416, -0.1050571, -0.03505838, 0.138108, 0.1653704, -0.08911968, -0.2578657, -0.2204199, -0.6184889, 0.367137, 0.1569906, -0.08947502, -0.07724197, -0.045262, -0.007915007...
Genome-wide association studies of suicidal behaviors: a review.
Suicidal behaviors represent a fatal dimension of mental ill-health, involving both environmental and heritable (genetic) influences. The putative genetic components of suicidal behaviors have until recent years been mainly investigated by hypothesis-driven research (of "candidate genes"). But technological progress in...
25,219,938
[ -0.2180428, -0.1645112, 0.08517018, -0.1391727, 0.129846, -0.02037067, -0.3600796, -0.1476511, -0.08139607, -0.04862778, 0.1395032, 0.09675831, -0.003547255, -0.003771844, -0.3944811, 0.1658846, -0.148255, 0.2370722, 0.0554086, 0.03105801, 0.08207594, 0.288719, -0.1266864...
Autism in DSM-5 under the microscope: implications to patients, families, clinicians, and researchers.
The changes in the diagnostic classification of the pervasive developmental disorders from the 4th edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV) to DSM-5 are expected to affect patients with autism, their families, as well as clinicians and researchers in the field of autism. This artic...
25,219,947
[ -0.1480683, 0.06799928, 0.3542641, -0.08074619, 0.1301816, -0.06842598, -0.1683798, 0.02365256, 0.03640065, -0.3028215, 0.1177292, 0.2849695, -0.362987, -0.2745406, -0.2254781, -0.05745585, -0.3592164, 0.1815902, 0.145949, -0.3537245, -0.02306466, 0.4246193, -0.1730142, ...
Granulosa cell tumor of the ovary--an incidental finding during caesarean section--a rare case report.
Approximately one-fourth of the ovarian neoplasms and cysts are diagnosed incidentally during caesarean section. The possibility of borderline tumor or cancer should be considered although existence of ovarian malignancy in pregnancy is rare. We report a case of a rare solid malignant tumor of the ovary incidentally fo...
25,219,997
[ -0.01994711, -0.05315507, -0.2010905, -0.2607577, -0.05952879, -0.2471683, -0.02235343, -0.04654756, 0.0060349, 0.06886644, 0.1947916, 0.4431126, -0.1550777, 0.0734283, -0.2143939, -0.2712007, -0.716283, -0.1406267, 0.2448698, -0.3018202, 0.02939876, 0.3357556, -0.1049285...
NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy.
N-glycanase 1 (NGLY1) is a conserved enzyme that is responsible for the deglycosylation of misfolded N-glycosylated proteins in the cytoplasm prior to their proteasome-mediated degradation. Disruption of this degradation process has been associated with various neurologic diseases including amyotrophic lateral sclerosi...
25,220,016
[ -0.02650323, -0.5907583, -0.1454159, -0.3560072, -0.05635018, -0.08128551, 0.1175985, -0.07990875, 0.3290151, 0.1290951, 0.1363866, 0.08117387, -0.1694436, -0.1344144, 0.1775082, 0.2622718, -0.8724828, 0.01241882, -0.09500448, -0.1781674, -0.03717684, 0.477651, 0.02476112...
Effects of anxiety sensitivity on alcohol problems: evaluating chained mediation through generalized anxiety, depression and drinking motives.
To test whether the relations between anxiety sensitivity (AS), a transdiagnostic risk factor, and alcohol problems are explained by chained mediation models, from AS through anxiety or depressive symptoms then drinking motives in an at-risk sample. It was hypothesized that AS would influence alcohol problems through g...
25,220,033
[ -0.3132999, -0.007371855, -0.4657317, 0.2334042, 0.4413335, -0.2732358, -0.3520118, -0.1869314, 0.2483312, -0.04213408, -0.1253166, 0.1253502, 0.2018286, -0.2618391, 0.1850141, -0.1366508, -0.1737967, 0.1704688, -0.1689169, -0.1447509, -0.1984343, 0.1018962, -0.003117893,...
Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation.
Cohesin mediates sister chromatid cohesion by topologically entrapping sister DNA molecules inside its ring structure. Cohesin is loaded onto DNA by the Scc2/NIPBL-Scc4/MAU2-loading complex in a manner that depends on the adenosine triphosphatase (ATPase) activity of cohesin's Smc1 and Smc3 subunits. Subsequent cohesio...
25,220,052
[ 0.3101231, 0.1236127, -0.04477644, -0.1395279, 0.1506258, -0.2629521, -0.06561954, 0.2647267, 0.3416964, 0.4222793, 0.07795866, 0.01486904, -0.2478902, -0.1494805, -0.6682593, 0.4310439, -0.519787, 0.0003144635, -0.004940931, -0.04201113, 0.4043272, -0.2330727, -0.3640946...
Lgl regulates Notch signaling via endocytosis, independently of the apical aPKC-Par6-Baz polarity complex.
The Drosophila melanogaster junctional neoplastic tumor suppressor, Lethal-2-giant larvae (Lgl), is a regulator of apicobasal cell polarity and tissue growth. We have previously shown in the developing Drosophila eye epithelium that, without affecting cell polarity, depletion of Lgl results in ectopic cell proliferatio...
25,220,057
[ -0.2043707, -0.1949247, -0.4044142, -0.0527596, -0.2730287, -0.008119832, 0.1087029, 0.0237171, -0.0765228, 0.291041, -0.2088691, 0.4066575, -0.2635528, -0.3416522, -0.1106726, -0.2512382, -0.7680955, 0.1994252, 0.665179, -0.2596305, 0.539462, 0.4998824, -0.301419, 0.14...
Achieving minimum caseload requirements: an analysis of hospital quality control reports from 2004-2010.
Legally mandated minimum hospital caseload requirements for certain invasive procedures, including pancreatectomy, esophagectomy, and some types of organ transplantation, have been in effect in Germany since 2004. The goal of such requirements is to improve patient care by ensuring that patients undergo certain procedu...
25,220,064
[ -0.017447, -0.0007144282, -0.1867394, -0.01043612, 0.2094193, -0.3445057, 0.1483973, 0.3659319, -0.1075328, 0.382515, 0.02977734, -0.3043222, 0.2993079, -0.3656657, 0.1294012, 0.2531322, 0.2171219, 0.01522668, -0.2855876, 0.05112335, 0.3458014, -0.1051281, 0.2524426, 0....
Achieving minimum caseload requirements--an analysis of hospital discharge data from 2005-2011.
The German Federal Joint Committee (the highest decision-making body of physicians and health insurance funds in Germany) has established minimum caseload requirements with the goal of improving patient care. Such requirements have been in place for five types of surgical procedure since 2004 and were introduced for to...
25,220,065
[ 0.07691209, -0.04317325, -0.02773995, 0.3794428, 0.1587338, -0.4219472, 0.3596388, -0.004355232, -0.2273146, 0.1820371, 0.144766, -0.4325235, 0.1999269, -0.3121841, 0.06733374, 0.2594373, 0.1899051, 0.4387504, -0.1535329, 0.02380152, 0.1510561, 0.131481, 0.347445, 0.006...
A novel TMEM16A splice variant lacking the dimerization domain contributes to calcium-activated chloride secretion in human sweat gland epithelial cells.
Sweating is an important physiological process to regulate body temperature in humans, and various disorders are associated with dysregulated sweat formation. Primary sweat secretion in human eccrine sweat glands involves Ca(2+) -activated Cl(-) channels (CaCC). Recently, members of the TMEM16 family were identified as...
25,220,078
[ -0.1583478, -0.1837272, -0.2396799, -0.1709784, -0.1631091, -0.1170587, -0.1327771, -0.161991, 0.2689662, 0.2107346, 0.1252479, 0.1950629, -0.1443525, -0.5664892, 0.2103377, -0.4031084, -0.6479468, -0.1826258, -0.00422521, -0.1206371, 0.346269, 0.3155758, -0.1497037, 0....
School-based interventions for elementary school students with ADHD.
Children with attention-deficit/hyperactivity disorder (ADHD) experience significant difficulties with behavior, social functioning, and academic performance in elementary school classrooms. Although psychotropic medication may enhance classroom behavior, pharmacologic treatment is rarely sufficient in addressing the m...
25,220,080
[ -0.3337198, 0.6914448, -0.2025882, -0.2525067, 0.1575008, -0.1006735, -0.3096997, -0.07393824, -0.1369349, -0.3175523, 0.2624176, 0.4043826, -0.2844284, -0.1096206, -0.6938492, 0.2298447, -0.281482, 0.4783124, -0.1667491, 0.04531514, 0.04601023, 0.2923562, -0.04844034, ...
Lifestyle interventions to reduce risk of diabetes among women with prior gestational diabetes mellitus.
While lifestyle interventions involving exercise and a healthy diet in high-risk adults have been found to reduce progression to type 2 diabetes by >50%, little attention has been given to the potential benefits of such strategies in women with a history of gestational diabetes mellitus (GDM). We conducted a literat...
25,220,104
[ -0.2156641, 0.4140779, -0.06098978, 0.1742006, 0.2407441, -0.06653923, -0.3014027, -0.1596126, 0.146911, -0.1361631, 0.1777864, -0.04874565, -0.0988549, -0.5062546, -0.04659514, 0.02805601, -0.3599316, 0.279405, -0.0909453, -0.4732831, -0.396568, 0.1606211, -0.02598114, ...
Air/water interfacial formation of freestanding, stimuli-responsive, self-healing catecholamine Janus-faced microfilms.
A catecholamine freestanding film is discovered to be spontaneously formed at the air-water interface, and the film has unique properties of robust surface adhesiveness, self-healing, and stimuli-responsive properties. The interfacial film-producing procedure is a simple single step containing polyamines and catechol(a...
25,220,108
[ -0.3169376, 0.07452085, -0.02919812, -0.4172759, -0.06508417, 0.004838515, -0.3897563, 0.04772433, 0.1987589, 0.0285011, -0.1160737, 0.1220522, -0.048038, 0.04593115, -0.4687437, -0.08741546, -0.3998244, 0.04932297, -0.1093794, -0.07488007, 0.2836216, -0.3156684, -0.18167...
Administration of surfactant using less invasive techniques as a part of a non-aggressive paradigm towards preterm infants.
Traditional treatment of respiratory distress syndrome in preterm infants consisted of early intubation, mechanical ventilation and intra-tracheal administration of exogenous surfactant. Recently, non-invasive ventilation, which has shown some advantages in short- and long-term outcomes, has gained popularity for the i...
25,220,131
[ -0.2821837, 0.004818716, -0.2705896, -0.2284036, 0.06491086, 0.07574409, -0.26045, -0.2815378, -0.02531521, 0.08287142, 0.2054351, -0.1048689, -0.01416577, -0.1149278, -0.006021405, -0.1448143, -0.6190599, 0.1263271, -0.06865282, -0.2214523, 0.03291475, -0.121517, 0.11716...
Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel.
Absence seizures are manifestations of abnormal thalamocortical oscillations characterized by spike-and-wave complexes in EEG. Ethosuximide (ETX) is one of the principal medications against absence seizures. We investigate the effect of ETX on the Kir2.1 channel, a prototypical inward rectifier K(+) channel possibly pl...
25,220,134
[ 0.004448776, 0.1568566, -0.2559342, -0.1141908, 0.3927094, -0.1442123, -0.1266762, -0.1576367, 0.06364284, 0.1711554, -0.03116316, 0.1059784, -0.3101979, 0.4051709, -0.05877244, 0.07758112, -0.2556789, -0.04285777, -0.1558271, -0.02013768, 0.1694597, 0.1753568, -0.0924168...
3.0 T MRI arterial spin labeling and magnetic resonance spectroscopy technology in the application of Alzheimer's disease.
The purpose of this study was to investigate the changes in the cerebral blood flow (CBF) and spectrum variables in the posterior cingulate region of patients with AD under the detection of arterial spin labeling (ASL) and magnetic resonance spectroscopy (MRS). A total of 20 AD patients (8 males and 12 females; mean ag...
25,220,149
[ 0.09166846, 0.230282, 0.13457, 0.2846744, -0.03620334, -0.2369254, -0.0857703, 0.2660763, 0.01984237, -0.06394426, -0.09976295, 0.6160869, 0.184151, -0.01462279, -0.6777532, -0.2280324, -0.1080473, 0.1010819, -0.2474401, 0.4809569, 0.08839565, 0.2310075, 0.02197146, 0.0...
Present simple and continuous: emergence of self-regulation and contextual sophistication in adolescent decision-making.
Sophisticated, intentional decision-making is a hallmark of mature, self-aware behaviour. Although neural, psychological, interpersonal, and socioeconomic elements that contribute to such adaptive, foresighted behaviour mature and/or change throughout the life-span, here we concentrate on relevant maturational processe...
25,220,166
[ -0.279642, -0.01139376, -0.1868915, -0.2806357, 0.4047645, -0.5235309, -0.2080791, -0.2063149, -0.06994743, -0.03541426, -0.2118901, -0.06354316, -0.1003811, -0.06698108, -0.7099124, -0.1057111, -0.3849512, 0.2063762, -0.2919047, 0.1480295, 0.2445608, 0.3567536, -0.023001...
Randomness and preserved patterns in cancer network.
Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at the proteomic level. While the short range correlations in the eigenvalues exhib...
25,220,184
[ 0.1742563, 0.05817573, 0.04285529, 0.04789797, -0.08124825, -0.1645804, -0.1396946, 0.3376655, 0.3304519, -0.0601061, 0.1359349, 0.05215997, 0.02421561, 0.07209656, -0.2407912, 0.07110949, -0.1498563, 0.03042623, -0.02394738, -0.1899056, 0.03393852, 0.07498304, -0.1218677...
Socio-economic analysis for the authorisation of chemicals under REACH: a case of very high concern?
Under the European chemicals' legislation, REACH, substances that are identified to be of "very high concern" will de facto be removed from the market unless the European Commission grants authorisations permitting specific uses. Companies who apply for an authorisation without demonstrating "adequate control" of the r...
25,220,186
[ -0.05228984, 0.1235985, 0.1257953, 0.02788001, 0.3027422, -0.08902916, -0.1005836, 0.356312, 0.07764409, -0.3471351, 0.02668735, -0.06399442, -0.1519023, 0.3082396, -0.1508836, -0.09194134, 0.02100221, 0.4042046, 0.02205522, 0.470089, -0.06250728, 0.7230977, -0.1949723, ...
Senescence-associated-gene signature identifies genes linked to age, prognosis, and progression of human gliomas.
Senescence-associated genes (SAGs) are responsible for the senescence-associated secretory phenotype, linked in turn to cellular aging, the aging brain, and the pathogenesis of cancer. We hypothesized that senescence-associated genes are overexpressed in older patients, in higher grades of glioma, and portend a poor pr...
25,220,188
[ 0.2648368, 0.3275004, -0.1949151, -0.5960678, 0.1347994, -0.3129239, -0.09586652, 0.2705479, -0.1334323, 0.2820313, -0.03860847, -0.1575734, -0.1811011, -0.4020065, -0.5801066, -0.01526822, 0.1988465, 0.03358423, 0.0698259, 0.332652, 0.2776722, 0.3227538, -0.1171044, 0....
CD8αα⁺ innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity.
Innate immune responses are critical for mucosal immunity. Here we describe an innate lymphocyte population, iCD8α cells, characterized by expression of CD8α homodimers. iCD8α cells exhibit innate functional characteristics such as the capacity to engulf and kill bacteria. Development of iCD8α cells depends on expressi...
25,220,211
[ 0.008168847, -0.3235224, -0.03650972, 0.02036805, 0.04385851, -0.3088947, -0.09455745, 0.07004169, 0.1676559, 0.1212717, -0.07580964, 0.2054133, -0.1855446, -0.1280089, -0.5399775, -0.2544694, -0.4258157, -0.2662089, -0.226779, 0.09346438, 0.4076821, 0.3900236, -0.0842747...
Isolation of the copper redox steps in the standard selective catalytic reduction on Cu-SSZ-13.
Operando X-ray absorption experiments and density functional theory (DFT) calculations are reported that elucidate the role of copper redox chemistry in the selective catalytic reduction (SCR) of NO over Cu-exchanged SSZ-13. Catalysts prepared to contain only isolated, exchanged Cu(II) ions evidence both Cu(II) and Cu(...
25,220,217
[ -0.2119509, -0.01468451, -0.2358915, 0.1308044, 0.1159078, -0.01073218, -0.5464274, -0.007269214, 0.1451451, 0.1028377, -0.1991135, -0.09763347, 0.1376323, -0.2368223, -0.662239, -0.1148194, -0.4674697, 0.03337584, -0.03248567, 0.393488, 0.01645229, 0.1001156, -0.03246976...