title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Pivotal roles of lymphatic endothelial cell layers in the permeability to hydrophilic substances through collecting lymph vessel walls: effects of inflammatory cytokines. | To address physiological and pathophysiological meanings of condensing effect of albumin in lymph through collecting lymph vessel walls, we established human lymphatic endothelial cells (LEC) and evaluated the size-dependent regulation of the permeability of such layers to hydrophilic substances. We also investigated t... | 25,229,432 | [
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Divergent lymphatic drainage routes from the heel to the inguinal region: anatomic study and clinical implications. | To determine routes of lymphatic drainage from the heel to the inguinal lymph nodes to assist in the clinical management of lower limb lymphatic disorders. Six lower limbs from three unembalmed human cadavers were studied. Under a surgical microscope, 6% hydrogen peroxide was used to detect lymphatic vessels on the med... | 25,229,435 | [
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Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor. | Stem cells contribute to regeneration of tissues and organs. Cells with stem cell-like properties have been identified in tumors from a variety of origins, but to our knowledge there are yet no reports on tumor-related stem cells in the human upper respiratory tract. In the present study, we show that a tracheal mucoep... | 25,229,469 | [
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Prediction equation for lower limbs lean soft tissue in circumpubertal boys using anthropometry and biological maturation. | Lean soft tissue (LST), a surrogate of skeletal muscle mass, is largely limited to appendicular body regions. Simple and accurate methods to estimate lower limbs LST are often used in attempts to partition out the influence of body size on performance outputs. The aim of the current study was to develop and cross-valid... | 25,229,472 | [
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Screening Medicinal Plants for Use against Dactylogyrus intermedius (Monogenea) Infection in Goldfish. | Abstract Methanol extracts of 24 traditional medicinal plants with potential anthelmintic activity against Dactylogyrus intermedius (Monogenea) in Goldfish Carassius auratus were investigated. Abrus cantoniensis, Citrus medica, Dioscorea collettii, and Polygonum multiflorum exhibited 100% activity and were selected for... | 25,229,482 | [
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Nanoparticle-based diagnostic imaging of inflammation in rheumatic disease. | A variety of imaging modalities assists in the diagnosis and assessment of rheumatoid arthritis and of other rheumatic disorders; however, the definitive diagnosis of inflammatory arthritides can be challenging, especially in the early stages of disease. Consequently, there is significant research underway in expanding... | 25,229,498 | [
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Experimental model of obtaining tissue adipose, mesenchymal stem cells isolation and distribution in surgery flaps in rats. | To investigate the experimental model for obtaining adipose tissue, isolation, characterization of mesenchymal stem cells and evaluation of their distribution in the tram flap in rats. Five rats of Wistar were randomly assigned to two groups. In group I, three animals underwent removal of adipose tissue in the groin pr... | 25,229,511 | [
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L-FABP and I-FABP expression in newborn rats changes inversely in the model of necrotizing enterocolitis. | To determine the expression of hepatic L-FABP and intestinal I-FABP in an experimental model of necrotizing enterocolitis (NEC) in neonatal rats. Newborn Sprague-Dawley rats were divided into four groups: Control (C1) - exclusive breastfeeding at the first and sixth procedures (C6), NEC1 - fed formula milk and submitte... | 25,229,514 | [
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Evaluation of CART-, glucagon-, and insulin-immunoreactive cells in the pancreas of an experimental rat model of unilateral renal artery stenosis. | Hypertension is one of the most frequently occurring diseases worldwide. Approximately 10% of the population with hypertension reveal the secondary type of hypertension. The aim of this study was to evaluate the cells containing CART, insulin and glucagon in the pancreas of rats with renovascular hypertension. An exper... | 25,229,552 | [
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Age-specific influence of wheezing phenotypes on pre-adolescent and adolescent health-related quality of life. | Asthma is associated with diminished health-related quality of life (HRQoL). Particularly in adolescence, asthma may be under-diagnosed and undertreated or poorly managed. Therefore, we aimed to determine the association between childhood wheezing phenotypes rather than asthma and adolescent HRQoL in children aged 10-1... | 25,229,563 | [
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Basaloid Carcinoma of the Breast Mimicking Cutaneous Basaloid Neoplasms. | Basaloid carcinoma of the breast (BCB) is a rare, triple-negative aggressive primary breast tumor that can closely mimic cutaneous basal cell carcinoma (BCC), neuroendocrine tumors, adnexal neoplasms, and other primary breast tumors. Accurate diagnosis of this tumor is critical for appropriate clinical management. We a... | 25,229,570 | [
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Assessing the likely harms to kidney vendors in regulated organ markets. | Advocates of paid living kidney donation frequently argue that kidney sellers would benefit from paid donation under a properly regulated kidney market. The poor outcomes experienced by participants in existing markets are often entirely attributed to harmful black-market practices. This article reviews the medical and... | 25,229,573 | [
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Optical properties of graphene superlattices. | In this work, the optical responses of graphene superlattices, i.e. graphene subjected to a periodic scalar potential, are theoretically reported. The optical properties were studied by investigating the optical conductivity, which was calculated using the Kubo formalism. It was found that the optical conductivity beco... | 25,229,612 | [
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New posology of potassium iodide for the treatment of cutaneous sporotrichosis: study of efficacy and safety in 102 patients. | The first therapeutic choice for the treatment of cutaneous sporotrichosis is oral itraconazole; however, the increase in cases of zoonotic transmission outbreak necessitates a search for effective and safe treatment alternatives. To evaluate a new potassium iodide (KI) posology as an alternative for the treatment of l... | 25,229,626 | [
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Dysfunction of emotional brain systems in individuals at high risk of mood disorder with depression and predictive features prior to illness. | Abnormalities of emotion-related brain circuitry, including cortico-thalamic-limbic regions underpin core symptoms of bipolar disorder (BD) and major depressive disorder (MDD). It is unclear whether these abnormalities relate to symptoms of the disorder, are present in unaffected relatives, or whether they can predict ... | 25,229,638 | [
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HPV-negative carcinoma of the uterine cervix: a distinct type of cervical cancer with poor prognosis. | Using highly sensitive polymerase chain reaction (PCR) techniques, we reanalysed all cervical carcinomas (CCs) found to be human papillomavirus (HPV)-negative by Hybrid Capture 2 (HC2) to determine the prevalence of true HPV-negativity. We also evaluated the characteristics of the patients with tumours with confirmed H... | 25,229,645 | [
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Optimization of extraction of circulating RNAs from plasma--enabling small RNA sequencing. | There are several protocols and kits for the extraction of circulating RNAs from plasma with a following quantification of specific genes via RT-qPCR. Due to the marginal amount of cell-free RNA in plasma samples, the total RNA yield is insufficient to perform Next-Generation Sequencing (NGS), the state-of-the-art tech... | 25,229,651 | [
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Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression. | Phloridzin (phlorizin or phloretin 2'-O-glucoside) is known for blocking intestinal glucose absorption. We have investigated the anticarcinogenic effect of phloridzin and its novel derivatives using human cancer cell lines. We have synthesised novel acylated derivatives of phloridzin with six different long chain fatty... | 25,229,655 | [
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Warm-up strategy and high-intensity endurance performance in trained cyclists. | To evaluate the influence of warm-up exercise intensity and subsequent recovery on intense endurance performance, selected blood variables, and the oxygen-uptake (VO2) response. Twelve highly trained male cyclists (VO2max 72.4 ± 8.0 mL · min-1 · kg-1, incremental-test peak power output (iPPO) 432 ± 31 W; mean ± SD) per... | 25,229,657 | [
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Skin preparation for preventing infection following caesarean section. | The risk of maternal mortality and morbidity (particularly postoperative infection) is higher for caesarean section than for vaginal birth. With the increasing rate of caesarean section, it is important that the risks to the mother are minimised as far as possible. This review focuses on different forms and methods for... | 25,229,700 | [
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Serosurvey of Crimean-Congo hemorrhagic fever virus in domestic animals, Gujarat, India, 2013. | Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease that causes a fatal hemorrhagic illness in humans. This disease is asymptomatic in animals. CCHF was first confirmed in a nosocomial outbreak in 2011 in Gujarat State. Another notifiable outbreak occurred in July, 2013, in Karyana Village, Amreli dist... | 25,229,708 | [
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Using developmental research to design innovative knowledge translation technology for spinal cord injury in primary care: Actionable Nuggets™ on SkillScribe™. | Actionable Nuggets™ for spinal cord injury (SCI) are a knowledge translation tool facilitating evidence-based primary care practice, originally developed in 2010 and refined in 2013. Evaluation results from these two phases of development have informed the design of SkillScribe™, an innovative electronic platform inten... | 25,229,739 | [
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Detection of monoamine oxidase a in brain of living rats with [18F]fluoroethyl-harmol PET. | The efficient radiosynthesis for the MAO-A ligand [(18) F]fluoroethyl-harmol is reported. Initial PET examinations reveal the ligand to be retained throughout rat brain during 90 min, whereas pretreatment with pargyline results in substantially increased washout, from which binding potentials in the range of 1.4-2.1 ca... | 25,229,748 | [
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TNFR2 and IL-12 coactivation enables slanDCs to support NK-cell function via membrane-bound TNF-α. | Human blood NK cells exert strong cytotoxicity against transformed cells and produce different cytokines and chemokines with an important role in modulating immune responses. However, the nature of NK-cell function depends on NK-cell interaction with other immune cells. One type of immune cells that communicate with NK... | 25,229,755 | [
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[Communicating research with social media]. | Participation is the new keyword of communication. In the scientific field, communication is a very complex task that can't ignore the careful consideration of the target audience. To minimize the difficulties, it is useful to rely on storytelling: it can greatly benefit from the space offered by social media that can ... | 25,229,757 | [
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Transformations in hallucinosis and the receptivity of the analyst. | Bion describes transformation in hallucinosis (TH) as a psychic defence present in elusive psychotic scenarios in which there is a total adherence to concrete reality: as the hallucinatory activity which physiologically infiltrates perception and allows us to know reality, setting it off against a background of familia... | 25,229,774 | [
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A retrospective review and observational study of outcomes and safety of bimatoprost ophthalmic solution 0.03% for treating eyelash hypotrichosis. | The efficacy and safety of bimatoprost ophthalmic solution 0.03% for treating hypotrichosis were shown in a randomized controlled trial and in an open-label study. To date, no data on real-world experience have been published. To evaluate long-term patient satisfaction, usage patterns, and safety of bimatoprost 0.03% i... | 25,229,783 | [
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Investigation of photoplethysmographs from the anterior fontanelle of neonates. | Photoplethysmography (PPG) signals have been investigated at a new anatomical site, the anterior fontanelle (ANTF), on the hypothesis that blood supply at this location is preferentially preserved during cases of poor peripheral circulation which might cause the commercial pulse oximeters to fail to estimate accurately... | 25,229,803 | [
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Community psychiatry's achievements. | Mental health care in the second half of the 20th century in much of the developed world has been dominated by the move out from large asylums. Both in response to this move and to make it possible, a pattern of care has evolved which is most commonly referred to as 'Community Psychiatry'. This narrative review describ... | 25,229,800 | [
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Polymorphous low-grade adenocarcinoma: a case series and determination of recurrence. | Information on polymorphous low-grade adenocarcinoma (PLGA) consists primarily of case reports and small institutional series with varying recurrence rates. In this report, we describe our institutional experience and conduct a review of the literature to assess the overall incidence of PLGA among oral salivary gland t... | 25,229,805 | [
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Diving and pregnancy: what do we really know? | Exercise during pregnancy has been advocated by many professional organizations to promote fetal heath and maternal well-being. Those same professional organizations do not recommend diving during pregnancy because of the potential adverse outcomes that have been observed in the animal model. In nonpregnant women, divi... | 25,229,824 | [
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Separation anxiety, attachment and inter-personal representations: disentangling the role of oxytocin in the perinatal period. | In this paper, we aimed to assess cross-sectionally and longitudinally associations between disturbances in maternal early attachment experiences, symptoms of separation anxiety and depression and oxytocin plasma levels. We examined a mediational model that tested the hypothesis that anxious attachment style arising fr... | 25,229,827 | [
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Synthesis and endothelin receptors binding affinity of new 1,3,5- substituted pyrrole-2-carboxylic acid derivatives. | The interest of researchers for ligands of the endothelin receptors ETA and ETB is due to their extensive therapeutic potential. In particular, receptor antagonists are useful in a number of diseases such as pulmonary hypertension, acute myocardial infarction, congestive heart failure, renal failure, and atherosclerosi... | 25,229,828 | [
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The standard centrifuge method accurately measures vulnerability curves of long-vesselled olive stems. | The standard centrifuge method has been frequently used to measure vulnerability to xylem cavitation. This method has recently been questioned. It was hypothesized that open vessels lead to exponential vulnerability curves, which were thought to be indicative of measurement artifact. We tested this hypothesis in stems ... | 25,229,841 | [
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Analysis of benzo[c]phenanthridine alkaloids in Eschscholtzia californica cell culture using HPLC-DAD and HPLC-ESI-MS/MS. | Effective HPLC-DAD and HPLC-ESI-MS/MS methods have been developed for the analysis of eight benzo[c]phenanthridine alkaloids (sanguinarine, chelirubine, macarpine, chelerythrine, dihydrosanguinarine, dihydrochelirubine, dihydromacarpine and dihydrochelerythrine), which are important metabolites in Eschscholtzia califor... | 25,229,843 | [
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Metabolic stability and inhibitory effect of O-methylated theaflavins on H2O2-induced oxidative damage in human HepG2 cells. | Seven new O-methylated theaflavins (TFs) were synthesized by using O-methyltransferase from an edible mushroom. Using TFs and O-methylated TFs, metabolic stability in pooled human liver S9 fractions and inhibitory effect on H(2)O(2)-induced oxidative damage in human HepG2 cells were investigated. In O-methylation of th... | 25,229,848 | [
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Dynamic changes in genes related to glucose uptake and utilization during pig skeletal and cardiac muscle development. | Skeletal and cardiac muscle have important roles in glucose uptake and utilization. However, changes in expression of protein coding genes and miRNAs that participate in glucose metabolism during development are not fully understood. In this study, we investigated the expression of genes related to glucose metabolism d... | 25,229,851 | [
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Purification and characterization of three β-glycosidases exhibiting high glucose tolerance from Aspergillus niger ASKU28. | Production and utilization of cellulosic ethanol has been limited, partly due to the difficulty in degradation of cellulosic feedstock. β-Glucosidases convert cellobiose to glucose in the final step of cellulose degradation, but they are inhibited by high concentrations of glucose. Thus, in this study, we have screened... | 25,229,852 | [
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Evaluation of chitosan-binding amino acid residues of chitosanase from Paenibacillus fukuinensis. | Chitosan oligosaccharides longer than a hexamer have higher bioactivity than polymer or shorter oligosaccharides, such as the monomer or dimer. In our previous work, we generated Paenibacillus fukuinensis chitosanase-displaying yeast using yeast cell surface displaying system and demonstrated the catalytic base. Here w... | 25,229,853 | [
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In vitro evaluation of glyceric acid and its glucosyl derivative, α-glucosylglyceric acid, as cell proliferation inducers and protective solutes. | We demonstrate that 0.78 mm glyceric acid activated the proliferation of human dermal fibroblasts by about 45%, whereas 34 mm α-glucosylglyceric acid (GGA) increased collagen synthesis by the fibroblasts by 1.4-fold compared to that in the absence of GGA. The two substances also exerted protective effects on both DNA s... | 25,229,854 | [
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Gold-catalyzed tandem cycloisomerization/functionalization of in situ generated α-oxo gold carbenes in water. | A gold-catalyzed tandem cycloisomerization/functionalization of in situ generated α-oxo gold carbenes in water has been developed, which provides ready access to highly functionalized indole derivatives from o-alkynyl anilines and ynamides. Importantly, gold serves dual catalytic roles to mediate both the cycloisomeriz... | 25,229,883 | [
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Perception of quality of life of a group of individuals subjected to bariatric surgery. | The study sought to identify the state of health and quality of life of post-bariatric surgery patients. This was a cross-sectional study conducted in 2012 with the participation of 338 individuals attending the private practice of a bariatric surgeon from Medellín (Colombia). With prior signed informed consent, the su... | 25,229,900 | [
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Full-length genomic analysis of Korean porcine Sapelovirus strains. | Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, is associated with diarrhea, pneumonia, severe neurological disorders, and reproductive failure in pigs. However, the structural features of the complete PSV genome remain largely unknown. To analyze the structural features ... | 25,229,940 | [
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Altered spontaneous neural activity in first-episode, unmedicated patients with major depressive disorder. | Abnormal brain function is presumed to be a pathophysiological aspect of major depressive disorder (MDD). However, the underlying patterns of spontaneous neural activity have been poorly characterized and replicated to date. In this study, we applied a novel approach of fractional amplitude of low-frequency fluctuation... | 25,229,945 | [
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[Relationship between serum 25-hydroxyvitamin D and bone mineral density in children under 7 years old]. | To evaluate the endogenous vitamin D level and its correlation with bone mineral density (BMD) in children under 7 years old. Totally 6 838 children who visited the Growth and Development Clinic due to "growth retardation, night terrors, hyperhidrosis, and dysphoria" were enrolled in the study. Serum 25-hydroxyvitamin ... | 25,229,952 | [
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[Effect of structural family therapy on family structure and function in children with hematological tumors]. | To explore the effect of structural family therapy (SFT), which refers to the application of the theory and technology of SFT for improving the internal family environment of pediatric patients through reorganization of the family roles, tasks, and boundaries, on the family structure and function in children with hemat... | 25,229,957 | [
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Normal values for inspiratory muscle function in children. | Assessment of inspiratory muscle function (IMF) is limited in children with neuromuscular disorders, because respiratory muscle tests are poorly standardized and valid normative data are unavailable. We investigated maximum inspiratory pressure after exhalation to residual volume (MIP), mouth occlusion pressure (P0.1) ... | 25,229,979 | [
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Pharmacokinetics of florfenicol after intravenous administration in Escherichia coli lipopolysaccharide-induced endotoxaemic sheep. | Experiments in different animal species have shown that febrile conditions, induced by Escherichia coli lipopolysaccharide (LPS), may alter the pharmacokinetic properties of drugs. The objective was to study the effects of a LPS-induced acute-phase response (APR) model on plasma pharmacokinetics of florfenicol (FFC) af... | 25,229,993 | [
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Asymmetric α-photoalkylation of β-ketocarbonyls by primary amine catalysis: facile access to acyclic all-carbon quaternary stereocenters. | We describe the direct construction of all-carbon quaternary stereocenters via α-photoalkylation of β-ketocarbonyls with high efficacy and enantioselectivities by merging photoredox catalysis and primary amine catalysis. The open-shell photoradical approach enables asymmetric α-alkylations that are difficult under ther... | 25,229,998 | [
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Venous ulcer: risk factors and the Nursing Outcomes Classification. | To explore the relationship between the risk factors for the development of venous ulcers and the indicators of tissue integrity from the Nursing Outcomes Classification. A cross-sectional study conducted in 2013 in a university hospital in Natal/RN (Brazil). Fifty individuals selected by consecutive sampling participa... | 25,230,036 | [
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Cytoskeletal proteins associate with components of the ribosomal maturation and translation apparatus in Xenopus stage I oocytes. | Actin-based cytoskeleton (CSK) and microtubules may bind to RNAs and related molecules implicated in translation. However, many questions remain to be answered regarding the role of cytoskeletal components in supporting the proteins involved in steps in the maturation and translation processes. Here, we performed co-im... | 25,230,050 | [
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Acrodermatitis chronica atrophicans of the face: a case report and a brief review of the literature. | Acrodermatitis chronica atrophicans is a rare late manifestation of tick-borne Borrelia burgdorferi infection, manifesting as inflammatory and atrophic lesions on acral skin. We describe the case of a 73-year-old woman with skin changes progressed to marked atrophy on her left hand and an edematous inflammatory involve... | 25,230,062 | [
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Clinical evaluation of rigid gas permeable contact lenses and visual outcome after repaired corneal laceration. | To evaluate the clinical value of rigid gas permeable contact lenses (RGPCLs) in patients with traumatic corneal scarring and address implications of primary corneal repair. Eighteen subjects with a history of corneal laceration were fit with RGPCLs. Scar locations were divided into two zones; each patient was examined... | 25,230,077 | [
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Protonation states of remote residues affect binding-release dynamics of the ligand but not the conformation of apo ferric binding protein. | We have studied the apo (Fe(3+) free) form of periplasmic ferric binding protein (FbpA) under different conditions and we have monitored the changes in the binding and release dynamics of H2PO4(-) that acts as a synergistic anion in the presence of Fe(3+). Our simulations predict a dissociation constant in agreement wi... | 25,230,090 | [
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... |
Iron-catalyzed coupling of aryl sulfamates and aryl/vinyl tosylates with aryl Grignards. | The iron-catalyzed coupling of aryl sulfamates and tosylates with aryl Grignard reagents is reported for the first time. The methodology employs air-stable, low-cost FeF3·3H2O and the N-heterocyclic carbene ligand IPr·HCl as the preligand to form a long-lived catalyst upon treatment with aryl Grignards. The reaction pr... | 25,230,097 | [
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Determination of Cystatin C in human serum by isotope dilution mass spectrometry using mass overlapping peptides. | We propose a peptide-based isotope dilution mass spectrometry approach for Cystatin C determination in human serum samples, a clinical marker for renal status for which backup by a mass spectrometry based primary method has been missing so far. In contrast to common protocols, the isotope labelled version of the proteo... | 25,230,103 | [
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NiCo2O4 nanostructure materials: morphology control and electrochemical energy storage. | Three types of NiCo2O4 nanostructure, homogeneous NiCo2O4 nanoneedle arrays, heterogeneous NiCo2O4 nanoflake arrays and NiCo2O4 nanoneedle-assembled sisal-like microspheres are synthesized via facile solution methods in combination with thermal treatment. The NiCo2O4 nanoneedle arrays are evaluated as supercapacitor el... | 25,230,142 | [
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... |
Characterization of a radical S-adenosyl-L-methionine epimerase, NeoN, in the last step of neomycin B biosynthesis. | The last step of neomycin biosynthesis is the epimerization at C-5‴ of neomycin C to give neomycin B. A candidate enzyme responsible for the epimerization was a putative radical S-adenosyl-L-methionine (SAM) enzyme, NeoN, which is uniquely encoded in the neomycin biosynthetic gene cluster and remained an unassigned pro... | 25,230,155 | [
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N-hydroxysuccinimidyl p-methoxybenzoate as suitable derivative reagent for isotopic dilution assay of biogenic amines in food. | We present a simple methodology for the simultaneous identification and determination of biogenic amines in food matrices, based on the use of a stable isotope-coded derivatization and liquid chromatography tandem mass spectrometry. The tagging reagent is N-hydroxysuccinimidyl ester of d(0)/d(4) -4-methoxybenzoic acid ... | 25,230,176 | [
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Characterization of mustard seeds and paste by DART ionization with time-of-flight mass spectrometry. | Direct analysis in real time (DART) is a novel technique with great potential for rapid screening analysis. The DART ionization method coupled with high-resolution time-of-flight mass spectrometry (TOF-MS) has been used for characterization of mustard seeds and table mustard. The possibility to use DART to analyse gluc... | 25,230,177 | [
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Proton-transfer-reaction mass spectrometry for the study of the production of volatile compounds by bakery yeast starters. | The aromatic impact of bakery yeast starters is currently receiving considerable attention. The flavor characteristics of the dough and the finished products are usually evaluated by gas chromatography and sensory analysis. The limit of both techniques resides in their low-throughput character. In the present work, pro... | 25,230,182 | [
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Reliable liquid chromatography-mass spectrometry method for investigation of primary aromatic amines migration from food packaging and during industrial curing of multilayer plastic laminates. | Primary aromatic amines (PAAs) can migrate from packaging into food from different sources such as polyurethanic adhesives used for the manufacture of multilayer films, which may contain residual aromatic isocyanates, or recycled paperboard, because of the presence of azo dyes in the printed paper massively used in the... | 25,230,184 | [
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An atmospheric pressure chemical ionization-ion-trap mass spectrometer for the on-line analysis of volatile compounds in foods: a tool for linking aroma release to aroma perception. | An atmospheric pressure chemical ionization ion-trap mass spectrometer was set up for the on-line analysis of aroma compounds. This instrument, which has been successfully employed for some years in several in vitro and in vivo flavour release studies, is described for the first time in detail. The ion source was fashi... | 25,230,189 | [
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The impact of dementia development concurrent with Parkinson's disease: a new perspective. | Dementia is the leading cause of disability worldwide among chronic diseases in the elderly and is a major contributor to mortality. Importantly, dementia that develops as a comorbid condition significantly compounds the burden of disease on the person, their caregivers and the health care system. Dementia is a frequen... | 25,230,219 | [
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Cholinergic system dysfunction and neurodegenerative diseases: cause or effect? | Acetylcholine (ACh) has been the first molecule to be identified as neurotransmitter. The cholinergic and cholinoceptive areas, both in central and peripheral nervous system, have been well documented. Acetylcholine has been described to control, during embryogenesis, cell proliferation as well as neuron and glial cell... | 25,230,223 | [
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Computational study of human tyrosine hydroxylase mutants to uphold [4-(Propan-2-yl) Phenyl]Carbamic acid as a potential inhibitor. | Neurodegenerative diseases that afflict nervous system are characterized by progressive nervous system dysfunction and associated with the one-set of many diseases like Segawa's syndrome (recessive form), autosomal recessive L-dopa-responsive dystonia, L-dopa non-responsive dystonia or progressive early-onset encephalo... | 25,230,230 | [
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Adjuncts should always be used in pediatric regional anesthesia. | A number of different adjuncts to local anesthetics can be used to prolong and optimize postoperative pain relief following regional anesthesia in children. The present text provides a slightly opinionated but evidence-based argument in favor of this practice. | 25,230,242 | [
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Markers of the progression of complications in patients with type 2 diabetes: a one-year longitudinal study. | Hyperglycemia induces tissue damage and complications by mechanisms that produce advanced glycation end-products (AGEs) and inflammation.To investigate the factors associated with the progression of complications in Type 2 diabetes patients.We recruited 157 patients (110 women and 47 men) with diabetes for more than 5 ... | 25,230,243 | [
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Preparation, characterization and origin of highly active and thermally stable Pd-Ce0.8Zr0.2O2 catalysts via sol-evaporation induced self-assembly method. | The Pd-Ce-Zr solid solution catalysts were in situ synthesized by a sol-evaporation induced self-assembly (SEISA) method. The catalytic performances of the as-prepared catalysts for CO oxidation and their physicochemical properties were investigated with various characterization techniques. The catalysts with low dopin... | 25,230,254 | [
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Quantifying mobile and immobile zones during simulated stormwater infiltration through a new permeable pavement material. | We have designed a new eco-material for use in permeable pavements in view to ensuring the sustainable management of stormwater in urban areas. The specific characteristic of this material is that it allows the infiltration of rainfall, storing the infiltrated water and trapping the pollutants carried by runoff such as... | 25,230,252 | [
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Arthroscopic single-bundle versus triple-bundle anterior cruciate ligament reconstruction. | The aim of this prospective, randomized study was to compare the clinical results of arthroscopic single-bundle (SB) and triple-bundle (TB) anterior cruciate ligament (ACL) reconstruction. The study included 105 patients who underwent arthroscopic SB ACL and TB ACL reconstruction. Anterior stress radiographs and the ma... | 25,230,264 | [
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... |
Distal tibial osteochondroma causing fibular deformity and deep peroneal nerve entrapment neuropathy: a case report. | Osteochondromas are the most common benign bone tumors, comprising 9% of all bone tumors and 35% of benign bone tumors. They are frequently diagnosed incidentally. Osteochondromas are mostly asymptomatic, but may cause mechanical findings depending on the location and size of the tumor. Rarely, they may originate from ... | 25,230,273 | [
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[Recommendations for physical exercise practice during pregnancy: a critical review]. | Physical exercise is recommended for all healthy pregnant women. Regular practice of exercises during pregnancy can provide many physical and psychological benefits, with no evidence of adverse outcomes for the fetus or the newborn when exercise is performed at mild to moderate intensity. However, few pregnant women en... | 25,230,282 | [
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Probable interaction between an oral vitamin K antagonist and turmeric (Curcuma longa). | We report a probable interaction between a vitamin K antagonist, fluindione, and the herbal medicine turmeric that resulted in the elevation of the international normalized ratio (INR). The case presented here underlines the importance of considering potential exposure to herbal medications when assessing adverse effec... | 25,230,280 | [
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Effect of intracoronary anisodamine and diltiazem administration during primary percutaneous coronary intervention in acute myocardial infarction. | The aim of this study was to examine the role of intracoronary anisodamine and diltiazem administration performed before stenting on the immediate angiographic and clinical outcome in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). STEMI patients dur... | 25,230,304 | [
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Raman spectroscopy for in-line water quality monitoring--instrumentation and potential. | Worldwide, the access to safe drinking water is a huge problem. In fact, the number of persons without safe drinking water is increasing, even though it is an essential ingredient for human health and development. The enormity of the problem also makes it a critical environmental and public health issue. Therefore, the... | 25,230,309 | [
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Screen-printed resistive pressure sensors containing graphene nanoplatelets and carbon nanotubes. | Polymer composites with nanomaterials such as graphene nanoplatelets and carbon nanotubes are a new group of materials with high application possibilities in printed and flexible electronics. In this study such carbon nanomaterials were used as a conductive phase in polymer composites. Pastes with dispersed nanomateria... | 25,230,310 | [
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Predictors of mortality in pediatric patients on venoarterial extracorporeal membrane oxygenation. | Currently, there are no established echocardiographic or hemodynamic predictors of mortality after weaning venoarterial extracorporeal membrane oxygenation in children. We wished to determine which measurements predict mortality. Over 3 years, we prospectively assessed six echo and six hemodynamic variables at 3-5 circ... | 25,230,312 | [
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Prevalence and outcome of diastolic dysfunction in children with fluid refractory septic shock--a prospective observational study. | Our primary objective was to determine the prevalence and outcome of diastolic dysfunction in children with fluid refractory septic shock. The secondary objective was to determine possible early predictors of diastolic dysfunction. Prospective observational study. PICU of a tertiary care teaching hospital. Consecutive ... | 25,230,313 | [
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Induction of hyperandrogenism in lean reproductive-age women stimulates proatherogenic inflammation. | We determined the effect of hyperandrogenemia as observed in polycystic ovary syndrome (PCOS) on fasting and glucose-stimulated proatherogenic inflammation markers in lean healthy reproductive-age women. Sixteen lean healthy ovulatory reproductive-age women were treated with 130 mg of DHEA or placebo (n=8 each) for 5 d... | 25,230,323 | [
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Clostridium difficile-induced colitis in mice is independent of leukotrienes. | Clostridium difficile is the major cause of antibiotic-associated diarrhea and pseudomembranous colitis in healthcare settings. However, the host factors involved in the intestinal inflammatory response and pathogenesis of C. difficile infection (CDI) are largely unknown. Here we investigated the role of leukotrienes (... | 25,230,329 | [
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Hydrogen sulfide: a neuromodulator and neuroprotectant in the central nervous system. | Hydrogen sulfide (H2S) used to be known as a toxic gas. However, in the last two decades, accumulating evidence has revealed its role as a bioactive molecule in the biological systems. H2S has relatively high expression in the brain, exerting multiple functions in both health and diseases. It modulates neurotransmissio... | 25,230,373 | [
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0.08323253,
0.02991688,
0.1225331,
-0.2380955,
0.2334116,
-0.02552244,
0.128143,
0.0168541,
0.0160074,
-0.1858318,
-0.06855996,
-0.02721011,
-0.07191076,
-0.04611388,
0.2783326,
-0.0977389... |
[Simultaneous procedure in patients with abdominal aortic aneurysm and renal carcinoma]. | Renal carcinoma (RC) is present in 0.1-3% of patients with abdominal aortic aneurysm (AAA). There are several options for surgical solution as regards the type and timing of the procedure. The authors discuss the simultaneous AAA resection and radical nephrectomy as a treatment option. 1168 patients with AAA including ... | 25,230,387 | [
-0.1386664,
0.1961283,
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0.2495553,
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0.21173,
0.02073068,
0.2555283,
0.4811293,
0.1242949,
-0.103623,
0.489... |
Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts. | We compared mouse embryonic stem (ES) cells and fibroblasts (MEFs) for their ability to metabolically activate the environmental carcinogens benzo[a]pyrene (BaP), 3-nitrobenzanthrone (3-NBA) and aristolochic acid I (AAI), measuring DNA adduct formation by (32)P-postlabelling and expression of xenobiotic-metabolism gene... | 25,230,394 | [
0.01168569,
0.2465996,
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0.2770775,
0.04518108,
0.2116644,
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0.266066,
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0.2409345,
0.2356883,
0.1437271,
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-0.... |
Superior dehydrogenation/hydrogenation kinetics and long-term cycling performance of K and Rb cocatalyzed Mg(NH(2))(2)-2LiH system. | The coaddition of KH and RbH significantly improves the hydrogen storage properties of the Mg(NH2)2-2LiH system. An Mg(NH2)2-2LiH-0.04KH-0.04RbH composite was able to reversibly store 5.2 wt % H2 when the dehydrogenation operates at 130 °C and the hydrogenation operates at 120 °C. The isothermal dehydrogenation rate at... | 25,230,404 | [
-0.3462926,
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0.02394047,
... |
Landscape corridors can increase invasion by an exotic species and reduce diversity of native species. | Landscape corridors are commonly used to mitigate negative effects of habitat fragmentation, but concerns persist that they may facilitate the spread of invasive species. In a replicated landscape experiment of open habitat, we measured effects of corridors on the invasive fire ant, Solenopsis invicta, and native ants.... | 25,230,454 | [
0.1884098,
0.09583632,
0.144711,
0.07282221,
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0.1873474,
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The impact of seasonality in temperature on thermal tolerance and elevational range size. | Environmental temperature variation can influence physiology, biogeography, and life history, with large consequences for ecology, evolution, and the impacts of climate change. Based on the seasonality hypothesis, greater annual temperature variation at high latitudes should result in greater thermal tolerance and, con... | 25,230,465 | [
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0.008261617,
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0.1340032,
0.007127488,
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0.1659653,
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Variability in root production, phenology, and turnover rate among 12 temperate tree species. | The timing of fine root production and turnover strongly influences both the seasonal potential for soil resource acquisition among competing root systems and the plant fluxes of root carbon into soil pools. However, basic patterns and variability in the rates and timing or fine root production and turnover are general... | 25,230,473 | [
0.03774786,
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0.5115401,
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... |
Chemical evidence for the liverwort complex, Chiloscyphus concavus and C. horizontalis. | During the phytochemical study of Chilean liverworts from Tierra del Fuego, two species were collected, Chiloscyphus concavus (Steph.) Hässel and C. horizontalis (Hook.) Nees. Their crude extracts, when analyzed by TLC and GC-MS, showed identical phytochemical profiles. In view of the macro- and micro-morphological dif... | 25,230,488 | [
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0.3005664,
0.08944868,
0.1893624,
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-0... |
Antioxidant properties of phenolic compounds from Baccharis articulata and B. usterii. | As a continuation of our research on the Baccharis genus, the evaluation of the antioxidant effect by TRAP and TBARS assays of three isolated compounds from n-butanol fractions of B. articulata and B. usterii is reported. The structures of these compounds were established as 4-O-beta-D-glucopyranosyl-3,5-dimethoxybenzy... | 25,230,498 | [
-0.121062,
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0.3812804,
0.3839408,
0.498602,
0.03593827,
-0.2242098,
-... |
Anti-inflammatory activity of constituents isolated from Terminalia chebula. | This study was aimed at the evaluation of the anti-inflammatory activity of twelve compounds isolated from the methanolic extract of fruits of Terminalia chebula. The activity was determined in terms of their ability to inhibit inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrop... | 25,230,505 | [
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0.2195402,
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0.0... |
Quantification and comparison of extraction methods for alkaloids in Aegle marmelos leaves by HPLC. | The leaves of Aegle marmelos are reported to contain multi-bioactive classes of compounds including coumarins, furanocoumarins and alkaloids. HPLC analysis of the crude extract was challenging due to low concentrations of the compounds in the leaves. Five compounds visible in the HPLC chromatogram were separated and id... | 25,230,509 | [
0.03635997,
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0.5030044,
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0.09561187,
0.2218689,
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0.01130... |
Symptoms and health complaints and their association with perceived stress at university: survey of students at eleven faculties in Egypt. | This study examined the relationships between perceived stress and a range of self reported symptoms and health complaints in a representative sample of students at one university in Egypt. The data (3,271 students) was collected during the academic year 2009-2010 at eleven faculties at the university of Assiut city, E... | 25,230,535 | [
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0.1480741,
0.1375384,
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0.06703003,
-0.0688... |
Smoking, awareness of smoking-associated health risks, and knowledge of national tobacco legislation in Gaza, Palestine. | To assess university students' extent of smoking, knowledge of smoking health risks, and awareness of existing national anti-smoking laws. Self-administered questionnaire was employed across 7 universities (1,104 students, equal proportions of males and females) located in Gaza Strip, Palestine. About 55% of participan... | 25,230,536 | [
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0.2810651,
0.2044743,
0.003574543,
... |
[Comparison of medical practices of 'massage' and 'gymnastics' - at the end of the 19th and the beginning of the 20th century (England, France, Germany, Switzerland)]. | Massage and medical gymnastics are very ancient form of medical practices and knowledge, nevertheless they seem to focus a growing attention between 1860 and World War I in Europe. These practices know a quick institutionalization, and the physiotherapy or "kinesitherapy" emerge as a discipline with some more structure... | 25,230,528 | [
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0.2447235,
-0.5539519,
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0.3017271,
0.2560677,
-0.1830971,
... |
[Titanium dioxide nanoparticles: occupational exposure limits]. | Titanium dioxide (TiO2) is produced in Poland as a high production volume chemical (HPVC). It is used mainly as a pigment for paints and coatings, plastics, paper, and also as additives to food and pharmaceuticals. Titanium dioxide nanoparticles are increasingly applied in cosmetics, textiles and plastics as the ultrav... | 25,230,569 | [
-0.07850557,
-0.1785177,
0.08183791,
0.08440387,
0.01976324,
-0.2210743,
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0.2415451,
0.3575078,
0.04625331,
-0.03395034,
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0.07701468,
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-0.3869509,
0.281364,
0.3109513,
-0.05558346,
0.07553969,
0.4321944,
-0.2043101... |
Ex vivo application of endocytoscopy for determining the longitudinal extent of bile duct cancer: a pathological analysis of 28 resected cases. | The aim was to examine the diagnostic ability of an endocytoscope system (ECS) for detecting the longitudinal extent of bile duct cancer. We observed the surfaces of the bile duct of 28 consecutive patients undergoing biliary surgery both directly and under methylene blue staining by using an ECS. Based on the change i... | 25,230,590 | [
-0.07838526,
-0.1441457,
-0.467005,
-0.009966985,
-0.05683872,
-0.0677925,
-0.09281068,
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0.1289847,
0.002934781,
-0.06740503,
0.1285103,
0.08860631,
0.1155474,
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-0.4982455,
0.2526228,
-0.04165773,
-0.1966476,
0.1940669,
-0.167041,
0.05323... |
Dengue. | Dengue viruses have spread rapidly within countries and across regions in the past few decades, resulting in an increased frequency of epidemics and severe dengue disease, hyperendemicity of multiple dengue virus serotypes in many tropical countries, and autochthonous transmission in Europe and the USA. Today, dengue i... | 25,230,594 | [
-0.2028339,
0.2465554,
0.03745633,
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0.0074037,
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0.141573,
0.2409817,
0.1803911,
-0.2301486,
-0.02908675,
0.1860503,
-0.2825908,
-... |
Ancient human genomes suggest three ancestral populations for present-day Europeans. | We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west E... | 25,230,663 | [
-0.003238125,
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0.03044669,
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0.3311398,
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0.06791085,
0.1324378,
0.2759866,
-0.2665406... |
Cross-sectional analysis of the reporting of continuous outcome measures and clinical significance of results in randomized trials of non-pharmacological interventions. | Reporting the scoring details of continuous outcome measures in randomized trials allows readers to interpret the size of any effect of the intervention. This study aimed to determine, in a sample of randomized trials: 1) the completeness of reporting of scoring details for continuous outcome measures, and 2) whether t... | 25,230,673 | [
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0.001106298,
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0.04176805,
-0.2968409,
0.3939164,
0.009105049,
0.1417021,
-0.0361... |
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