title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Generalization of Carey's equality and a theorem on stationary population. | Carey's Equality pertaining to stationary models is well known. In this paper, we have stated and proved a fundamental theorem related to the formation of this Equality. This theorem will provide an in-depth understanding of the role of each captive subject, and their corresponding follow-up duration in a stationary po... | 25,230,675 | [
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The complete mitochondria genome of Chrysomya pinguis (Diptera: Calliphoridae). | Chrysomya pinguis (Ch. pinguis) belongs to blowfly species of great medical and forensic importance. In this study, we report the complete mitochondrial genome of the Ch. pinguis for species identification. The 38 genes presented in the 15,838 bp circular genome has been found in a typical Metazoan genome, of which the... | 25,230,700 | [
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The complete mitochondrial genome sequence of an endometrial cancer inbred Donryu rat model. | The Donryu rat strain is a commonly used model for endometrial cancer disease study. We sequenced this rat strain mitochondrial genome for the first time (GenBank Accession No. KM114605). Its mitogenome was 16,307 bp and coding 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes. A total of 96 SNPs we... | 25,230,703 | [
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DUSP28 contributes to human hepatocellular carcinoma via regulation of the p38 MAPK signaling. | DUSP28, a member of the atypical dual‑specificity phosphatase (DUSP) family, is a candidate tumor-related gene in hepatocellular carcinoma (HCC) selected by genome‑wide approach, but its pathological role in HCC has not been elucidated. Here, we report for the first time that DUSP28 is involved in HCC progression. Quan... | 25,230,705 | [
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piRNA identification based on motif discovery. | Piwi-interacting RNA (piRNA) is a class of small non-coding RNAs about 24 to 32 nucleotides long, associated with PIWI proteins, which are involved in germline development, transposon silencing, and epigenetic regulation. Identification of piRNA loci on the genome is very useful for further studies in the biogenesis an... | 25,230,731 | [
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Social networking versus facebook advertising to recruit survey respondents: a quasi-experimental study. | Increasingly, social contact and knowledge of other people's attitudes and behavior are mediated by online social media such as Facebook. The main research to which this recruitment study pertains investigates the influence of parents on adolescent alcohol consumption. Given the pervasiveness of online social media use... | 25,230,740 | [
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Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models. | TAS-102 is a novel oral nucleoside antitumor agent containing trifluridine (FTD) and tipiracil hydrochloride (TPI). The compound improves overall survival of colorectal cancer (CRC) patients who are insensitive to standard chemotherapies. FTD possesses direct antitumor activity since it inhibits thymidylate synthase (T... | 25,230,742 | [
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Use of sodium hypochlorite for skin antisepsis before inserting a peripheral venous catheter: a pilot study. | Although it can be prevented, catheter-related bacteremia is common and dangerous. The antiseptics most widely used during insertion of peripheral venous catheters (PVCs) include povidone iodine, alcohol, and chlorhexidine. Another widely used antiseptic is a solution of 0.057 g sodium hypochlorite. This pilot study ex... | 25,230,748 | [
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IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation. | Eosinophils originate in the bone marrow from an eosinophil lineage-committed, IL-5Rα-positive, hematopoietic progenitor (eosinophil progenitor). Indeed, IL-5 is recognized as a critical regulator of eosinophilia and has effects on eosinophil progenitors, eosinophil precursors, and mature eosinophils. However, substant... | 25,230,753 | [
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A cross sectional survey examining the association between therapeutic relationships and service user satisfaction in forensic mental health settings. | This small-scale study examines an often neglected patient group (service users in forensic mental health settings). The research investigates their therapeutic relationship with staff and which therapeutic relationship factors are associated with their level of satisfaction with services. A cross sectional survey was ... | 25,230,757 | [
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Structure and photoluminescence of silver(i) trinuclear halopyrazolato complexes. | Five halogen substituted pyrazolates, 4-chloro-3,5-diisopropylpyrazole (4-Cl-3,5-iPr2pzH), 4-bromo-3,5-diisopropylpyrazole (4-Br-3,5-iPr2pzH), 4-iodo-3,5-diisopropylpyrazole (4-I-3,5-iPr2pzH), 4-chloro-3,5-diphenylpyrazole (4-Cl-3,5-Ph2pzH), and 4-bromo-3,5-diphenylpyrazole (4-Br-3,5-Ph2pzH), were conveniently prepared... | 25,230,795 | [
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Cerebral vasospasm patterns following aneurysmal subarachnoid hemorrhage: an angiographic study comparing coils with clips. | Cerebral vasospasm following aneurysmal subarachnoid hemorrhage (aSAH) results in significant morbidity due to ischemia. Subarachnoid hematoma evacuation during aneurysm clipping reduces the incidence of vasospasm. However, studies comparing endovascular coiling with open clipping have reported similar rates of spasm. ... | 25,230,840 | [
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A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract. | A new biflavone, 6,2',3″,5″,4‴-pentahydroxy-3,7″-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, β-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effe... | 25,230,855 | [
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[Study of the effects of high volume hemofiltration on extra vascular lung water and alveolar-arterial oxygen exchange in patients with septic shock]. | To explore the effects of high volume hemofiltration (HVHF) on inflammatory factors, extra vascular lung water and alveolar-arterial oxygen exchange in patients with septic shock. The data of 87 patients with septic shock underwent fluid resuscitation admitted to intensive care unit (ICU) of Shandong Provincial Hospita... | 25,230,859 | [
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[The assessment of ultrasonic measurement of superior vena cava blood flow for the volume responsiveness of patients with mechanical ventilation]. | To approach the evaluative effect of respiratory variation of superior vena cava peak flow velocity measured using transthoracic echocardiography (TTE) on fluid responsiveness in patients with mechanical ventilation. A prospective cohort study was conducted. All mechanical ventilated critically ill patients whose fluid... | 25,230,862 | [
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C5a stimulates the proliferation of breast cancer cells via Akt-dependent RGC-32 gene activation. | Complement system activation contributes to various immune and inflammatory diseases, as well as cancers.However, the role of complement activation in the proliferation of cancer cells is not clear. In the present study, we investigated the consequences of complement activation on the proliferation of breast cancer cel... | 25,230,890 | [
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Knowledge and use of edible mushrooms in two municipalities of the Sierra Tarahumara, Chihuahua, Mexico. | The Sierra Madre Occidental of Chihuahua in Northern Mexico is inhabited by indigenous Raramuris, mestizos, and other ethnic groups. The territory consists of canyons and ravines with pine, oak and pine-oak forests in the higher plateaus. A great diversity of potentially edible mushrooms is found in forests of the Muni... | 25,230,891 | [
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Thermogenic brown and beige/brite adipogenesis in humans. | Evidence from rodents established an important role of brown adipose tissue (BAT) in energy expenditure. Moreover, to sustain thermogenesis, BAT has been shown to be a powerful sink for draining and oxidation of glucose and triglycerides from blood. The potential of BAT activity in protection against obesity and metabo... | 25,230,914 | [
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Association of left atrial booster-pump function with heart failure symptoms in patients with severe aortic stenosis and preserved left ventricular ejection fraction. | Identification of heart failure (HF) symptoms in patients with severe aortic stenosis (AS) and preserved left ventricular (LV) ejection fraction (EF) is clinically important, but assessment of HF symptoms is challenging. It was recently reported that resting left atrium (LA) functions are related to exercise performanc... | 25,230,926 | [
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Association between serotype-specific antibody response and serotype characteristics in patients with pneumococcal pneumonia, with special reference to degree of encapsulation and invasive potential. | We studied the immunoglobulin (Ig) response to causative serotype-specific capsular polysaccharides in adult pneumococcal pneumonia patients. The serotypes were grouped according to their degree of encapsulation and invasive potential. Seventy patients with pneumococcal pneumonia, 20 of whom were bacteremic, were prosp... | 25,230,937 | [
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Factors associated with severe deep neck space infections: targeting multiple fronts. | To determine factors predictive of a severe deep neck space infection (DNSI), defined as those requiring surgery and/or postoperative intensive care unit (ICU) admission. To specifically examine dental practices and socioeconomic factors that may contribute to the development of a DNSI. Retrospective review. This study... | 25,230,978 | [
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The characteristics of the porcine (Sus scrofa) liver miRNAome with the use of next generation sequencing. | MicroRNAs (miRNAs) are a class of small, noncoding RNAs, which play a vital role in the regulation of gene expression by binding to the 3' untranslated region (3'UTR) of a target mRNA. Despite a significant improvement in the identification of miRNAs in a variety of species, the coverage of the porcine miRNAome is stil... | 25,230,983 | [
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Linking bioregulatory systems: reciprocal autonomic activation predicts sleep over 1 year in middle childhood. | This study examined reactivity to social-evaluative stress in the parasympathetic (PNS) and sympathetic (SNS) branches of the autonomic nervous system (ANS) as prospective predictors of sleep in middle childhood. Participants included 339 children (M age = 9 years and 5 months at T1; 54% female; 64% European American, ... | 25,230,991 | [
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Auras in generalized epilepsy. | We studied the frequency of auras in generalized epilepsy (GE) using a detailed semistructured diagnostic interview. In this cross-sectional study, participants with GE were drawn from the Epilepsy Phenome/Genome Project (EPGP). Responses to the standardized diagnostic interview regarding tonic-clonic (grand mal) seizu... | 25,230,998 | [
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Human polyomavirus 7-associated pruritic rash and viremia in transplant recipients. | Human polyomavirus 7 (HPyV7) is one of 11 HPyVs recently discovered through genomic sequencing technologies. Two lung transplant recipients receiving immunosuppressive therapy developed pruritic, brown plaques on the trunk and extremities showing a distinctive epidermal hyperplasia with virus-laden keratinocytes contai... | 25,231,015 | [
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High-level secretory expression and purification of unhydroxylated human collagen α1(III) chain in Pichia pastoris GS115. | Recombinant collagen and gelatin have been applied in biomedical materials field because of products from genetically engineered microorganisms with improved safety, traceability, reproducibility, and homogeneous quality. To obtain high-level secretory expression of single-chain full-length human collagen α1(III) chain... | 25,231,012 | [
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Robotic single-site hysterectomy: two institutions' preliminary experience. | To evaluate the feasibility, safety and peri- and postoperative outcomes of robotic single-site hysterectomy for gynaecological diseases. We studied 45 patients who underwent robotic single-site hysterectomy for benign and malignant disease at two institutions during May 2012-June 2013. We evaluated whether any correla... | 25,231,021 | [
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The ratio of acetate-to-glucose oxidation in astrocytes from a single 13C NMR spectrum of cerebral cortex. | The (13) C-labeling patterns in glutamate and glutamine from brain tissue are quite different after infusion of a mixture of (13) C-enriched glucose and acetate. Two processes contribute to this observation, oxidation of acetate by astrocytes but not neurons, and preferential incorporation of α-ketoglutarate into gluta... | 25,231,025 | [
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Rehabilitation of irradiated patients with chemically modified and conventional SLA implants: five-year follow-up. | The aim of this study is to evaluate the clinical and radiological parameters of standard SLA surface implants compared to chemically modified hydrophilic SLActive implants in irradiated patients after the initial 12-month loading period up to 5 years. Twenty patients with a mean age of 61·1 years were treated with den... | 25,231,029 | [
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Association of physical properties and maintenance of sterility of primary teeth in human tooth bank. | This study was carried out to evaluate the sterility and structural integrity of stored primary teeth in artificial saliva over a storage period of 12 weeks (3 months) in human tooth bank (HTB). A total of 80 freshly extracted teeth were taken and were categorized into four groups of 20 each. The samples were stored at... | 25,231,034 | [
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Obsessive compulsive disorder in dental setting. | Globally, 20% of children and adolescents suffer from a disabling psychologic illness. Among these, Obsessive Compulsive Disorder (OCD) is listed by the World Health Organization (WHO) as one of the 10 most disabling conditions, with prevalence rates of OCD in children ranging between 1 to 3%. Pediatric dentists are in... | 25,231,042 | [
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Type III B dens invaginatus: diagnostic and clinical considerations using 128-slice computed tomography. | Endodontic therapy is successful only when thorough knowledge of root canal morphology is understood. Dens invaginatus is malformation of teeth resulting from invagination of tooth before biological mineralization occurs. It is clinically significant with an early pulpal involvement and chronic periapical lesion, which... | 25,231,045 | [
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What makes people sick? Burmese refugee children's perceptions of health and illness. | Understanding children's perceptions of health and illness is important for health promotion so that age-appropriate health care services and preventative health programs can be developed. In this article, we discuss the perceptions and experiences of health and illness among refugee children, their health knowledge an... | 25,231,057 | [
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Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine. | Spectroscopic studies combined with computational analysis indicate the inherent conformational flexibility of the β-carbolin derivative evodiamine (EVD) featured with diverse pharmacological activities. Qualitative evaluation of the circular dichroism (CD) spectra of EVD enantiomers complemented with quantum chemical ... | 25,231,059 | [
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Gene network analysis: from heart development to cardiac therapy. | Networks offer a flexible framework to represent and analyse the complex interactions between components of cellular systems. In particular gene networks inferred from expression data can support the identification of novel hypotheses on regulatory processes. In this review we focus on the use of gene network analysis ... | 25,231,088 | [
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Sphingosine kinase 1 (Sphk1) negatively regulates platelet activation and thrombus formation. | Sphingosine 1-phosphate (S1P) is a powerful regulator of platelet formation. Enzymes generating S1P include sphingosine kinase 1. The present study thus explored the role of sphingosine kinase 1 in platelet formation and function. Activation-dependent platelet integrin αIIbβ3 activation and secretion of platelets lacki... | 25,231,106 | [
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Placental mesenchymal stem cells of fetal origin deposit epigenetic alterations during long-term culture under serum-free condition. | Fetal placental mesenchymal stem cells (fPMSCs) have shown promising cell therapy potentials. However, their genetic and epigenetic stability during in vitro propagation has not been well studied. We thus interrogated the methylation alterations and tumorigenicity of fPMSCs after in vitro expansion using serum-free med... | 25,231,124 | [
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Gleason drift in the NIHR ProtecT study. | There is increasing evidence of Gleason score (GS) drift in prostatic core biopsies during the last two decades. The ProtecT study is a randomized controlled study and provides an excellent cohort to study the effect of time, prostate-specific antigen (PSA) level, perineural invasion, tumour length and age on GS. The P... | 25,231,130 | [
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The 24-year clinical performance of porcelain laminate veneer restorations bonded with a two-liquid silane primer and a tri-n-butylborane-initiated adhesive resin. | This report describes the bonding technique and clinical course of porcelain laminate veneer restorations applied to discolored maxillary incisors and canines. The patient was an 18-year-old woman, and tooth reduction was limited to the enamel. Laminate veneer restorations were made with a feldspathic porcelain materia... | 25,231,150 | [
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New suture materials for midline laparotomy closure: an experimental study. | Midline laparotomy closure carries a significant risk of incisional hernia. This study examines the behavior of two new suture materials, an elastic material, polyurethane (PUe), and a barbed polydioxanone (PDXb) suture thread in a rabbit model of midline incision closure. Three 2-cm midline incisions were made in 68 N... | 25,231,161 | [
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Laparoscopic microwave ablation of human liver tumours using a novel three-dimensional magnetic guidance system. | Accurate antenna placement is essential for effective microwave ablation (MWA) of lesions. Laparoscopic targeting is made particularly challenging in liver tumours by the needle's trajectory as it passes through the abdominal wall into the liver. Previous optical three-dimensional guidance systems employing infrared te... | 25,231,167 | [
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Full-genome identification and characterization of NBS-encoding disease resistance genes in wheat. | Host resistance is the most economical, effective and ecologically sustainable method of controlling diseases in crop plants. In bread wheat, despite the high number of resistance loci that have been cataloged to date, only few have been cloned, underlying the need for genomics-guided investigations capable of providin... | 25,231,182 | [
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Differential impact of unrecognised brain infarction on stroke outcome in non-valvular atrial fibrillation. | There has been little information regarding the impact of unrecognised brain infarctions (UBIs) on stroke outcome in patients with non-valvular atrial fibrillation (NVAF). By using volumetric analysis of ischaemic lesions, we evaluated the potential impact of UBIs on clinical outcome according to their presence and cat... | 25,231,184 | [
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Clinicopathologic characteristics of breast cancer in BRCA-carriers and non-carriers in women 35 years of age or less. | Breast cancer diagnosed in women 35 years of age or less accounts for <2% of all breast cancer cases. Clinical and pathologic characteristics of early onset breast cancer are not well defined in BRCA mutation carriers and non-carriers. 194 women diagnosed with breast cancer at 35 years of age or less who had BRCA1/2... | 25,231,195 | [
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Directional hearing: from biophysical binaural cues to directional hearing outdoors. | When insects communicate by sound, or use acoustic cues to escape predators or detect prey or hosts they have to localize the sound in most cases, to perform adaptive behavioral responses. In the case of particle velocity receivers such as the antennae of mosquitoes, directionality is no problem because such receivers ... | 25,231,204 | [
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Detection of gastric precancerous conditions in daily clinical practice: a nationwide survey. | The burden of gastric precancerous conditions and factors associated with their detection have not been fully investigated in community-based settings. Little is known about adherence to Sydney system for histopathology of gastric biopsies. We aimed to investigate what really happens in clinical practice with regard to... | 25,231,208 | [
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Lacrimal disorders and surgery: historical perspectives. | The history and evolution of lacrimal surgeries has been a fascinating journey. And yet, as we move forward on this path in time, it appears not to have attracted students in sufficient numbers. This article provides a comprehensive history of surgical interventions for lacrimal disorders spanning the ancient and medie... | 25,231,209 | [
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Gluten-free dough-making of specialty breads: Significance of blended starches, flours and additives on dough behaviour. | The capability of different gluten-free (GF) basic formulations made of flour (rice, amaranth and chickpea) and starch (corn and cassava) blends, to make machinable and viscoelastic GF-doughs in absence/presence of single hydrocolloids (guar gum, locust bean and psyllium fibre), proteins (milk and egg white) and surfac... | 25,231,269 | [
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Effects of semi-group housing and floor type on pododermatitis, spinal deformation and bone quality in rabbit does. | The most common housing system for reproduction rabbits, individual cage housing on a wire floor, is increasingly scrutinized because of its potential detrimental impact on animal welfare. We compared three types of housing: (1) individual cage housing on a wire floor (3952 cm2/doe, maximum roof height 63 cm, one 1000 ... | 25,231,283 | [
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Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition. | Herpes simplex virus 1 (HSV-1) and HSV-2 are among the most prevalent human pathogens. Both viruses can recognize, via the surface envelope glycoprotein D (gD), human nectin-1 as a functional receptor. Previous studies have successfully elucidated the molecular basis of the binding between HSV-1 gD and nectin-1 by cocr... | 25,231,300 | [
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Elephant endotheliotropic herpesviruses EEHV1A, EEHV1B, and EEHV2 from cases of hemorrhagic disease are highly diverged from other mammalian herpesviruses and may form a new subfamily. | A family of novel endotheliotropic herpesviruses (EEHVs) assigned to the genus Proboscivirus have been identified as the cause of fatal hemorrhagic disease in 70 young Asian elephants worldwide. Although EEHV cannot be grown in cell culture, we have determined a total of 378 kb of viral genomic DNA sequence directly fr... | 25,231,303 | [
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The conserved disulfide bond within domain II of Epstein-Barr virus gH has divergent roles in membrane fusion with epithelial cells and B cells. | Epstein-Barr virus (EBV) infects target cells via fusion with cellular membranes. For entry into epithelial cells, EBV requires the herpesvirus conserved core fusion machinery, composed of glycoprotein B (gB) and gH/gL. In contrast, for B cell fusion it requires gB and gH/gL with gp42 serving as a cell tropism switch. ... | 25,231,307 | [
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Comparative genome analysis of four elephant endotheliotropic herpesviruses, EEHV3, EEHV4, EEHV5, and EEHV6, from cases of hemorrhagic disease or viremia. | The genomes of three types of novel endotheliotropic herpesviruses (elephant endotheliotropic herpesvirus 1A [EEHV1A], EEHV1B, and EEHV2) associated with lethal hemorrhagic disease in Asian elephants have been previously well characterized and assigned to a new Proboscivirus genus. Here we have generated 112 kb of DNA ... | 25,231,309 | [
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Vibration on board and health effects. | There is only limited knowledge of the exposure to vibrations of ships' crews and their risk of vibration-induced health effects. Exposure to hand-arm vibrations from the use of vibrating tools at sea does not differ from that in the land-based trades. However, in contrast to most other work places, seafarers are also ... | 25,231,326 | [
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0.5411702,
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Assessment of intelligence quotient among schoolchildren of fishermen community of Kutch, Gujarat, India. | The aim of the study was to assess the intelligence quotient of fishermen school children of Kutch, Gujarat, India. A descriptive cross-sectional study was conducted among 8 to 10 years old school children living in Kutch District, Gujarat, India, from January to February 2013. Seguin Form Board Test was used to assess... | 25,231,330 | [
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In Candida albicans hyphae, Sec2p is physically associated with SEC2 mRNA on secretory vesicles. | Candida albicans hyphae grow in a highly polarized fashion from their tips. This polarized growth requires the continuous delivery of secretory vesicles to the tip region. Vesicle delivery depends on Sec2p, the Guanine Exchange Factor (GEF) for the Rab GTPase Sec4p. GTP bound Sec4p is required for the transit of secret... | 25,231,350 | [
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Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis. | Chronic traumatic encephalopathy (CTE) is a recently revived term used to describe a neurodegenerative process that occurs as a long term complication of repetitive mild traumatic brain injury (TBI). Corsellis provided one of the classic descriptions of CTE in boxers under the name "dementia pugilistica" (DP). Much rec... | 25,231,386 | [
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Raising the bar for antineoplastic agents: how to choose threshold values for superiority trials in advanced solid tumors. | To establish the concept of minimum clinically meaningful outcome (mCMO) of treatment in advanced solid tumors, to establish its threshold and evaluate how many superiority trials of new antineoplastic agents pass this threshold. We chose overall survival as the primary indicator of patient benefit. Four conceptually d... | 25,231,398 | [
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A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014. | To estimate the maximum tolerated dose (MTD) for continuous oral administration of the γ-secretase inhibitor PF-03084014, determine the recommended phase II dose (RP2D), and evaluate safety and preliminary activity in patients with advanced solid tumors. This open-label, phase I study consisted of a dose-finding portio... | 25,231,399 | [
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Ecology of grazing lawns in Africa. | Grazing lawns are a distinct grassland community type, characterised by short-stature and with their persistence and spread promoted by grazing. In Africa, they reveal a long co-evolutionary history of grasses and large mammal grazers. The attractiveness to grazers of a low-biomass sward lies in the relatively high qua... | 25,231,416 | [
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Carotid Elongation Does Not Affect Angiographic Results of Mechanical Thrombectomy in Acute Stroke. | New techniques have substantially raised recanalization rates of mechanical thrombectomy in acute ischemic stroke in the last few years with initial prospective trials reporting good neurological outcome in up to 58 % of the cases. However some recent reports questioning the benefit of endovascular therapy have initiat... | 25,231,427 | [
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Central hypothyroidism in children. | Central congenital hypothyroidism (CCH) is an underdiagnosed disorder poorly described in childhood and adolescence. Congenital defects in thyroid-stimulating hormone (TSH) synthesis, secretion or bioactivity may lead to a state of 'regulatory' hypothyroidism expressed through aberrantly low or normal TSH levels and lo... | 25,231,446 | [
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Facilitators and barriers to weight loss and weight loss maintenance: a qualitative exploration. | The present study aimed to explore facilitators and barriers to weight loss (WL) and weight loss maintenance (WLM) in women who participated in a primary, 18-week comparative trial that promoted WL with an energy-restricted diet. Twenty-three women participated in seven focus groups conducted by a moderator and co-faci... | 25,231,461 | [
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Production of few-layer phosphorene by liquid exfoliation of black phosphorus. | We report the liquid exfoliation of black phosphorus in N-methyl-2-pyrrolidone to form few-layer phosphorene nanosheets. | 25,231,502 | [
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The neuro-ophthalmology of head trauma. | Traumatic brain injury (TBI) is a major cause of morbidity and mortality. Concussion, a form of mild TBI, might be associated with long-term neurological symptoms. The effects of TBI and concussion are not restricted to cognition and balance. TBI can also affect multiple aspects of vision; mild TBI frequently leads to ... | 25,231,523 | [
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Predictors of nosocomial pneumonia in intracerebral hemorrhage patients: a multi-center observational study. | Nosocomial pneumonia (NP) is a frequent complication among spontaneous intracerebral hemorrhage (sICH) patients. This study was aimed at identifying in-hospital risk factors that predispose sICH patients to NP. We identified 591 consecutive sICH subjects admitted to six tertiary care hospitals between 2008 and 2012. In... | 25,231,530 | [
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MicroRNA expression profile in exosome discriminates extremely severe infections from mild infections for hand, foot and mouth disease. | Changes of miRNAs in exosome have been reported in different disease diagnosis and provided as potential biomarkers. In this study, we compared microRNA profile in exosomes in 5 MHFMD and 5 ESHFMD as well as in 5 healthy children. Different expression of miRNAs in exosomes across all the three groups were screened usin... | 25,231,540 | [
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Long, titanium, cemented stems decreased late periprosthetic fractures and revisions in patients with severe bone loss and previous revision. | Long, cementless, femoral stem revisions are being used with increasing frequency. There is a relative lack of studies of late fractures after cementless implants, particularly in those patients who had a previous stem revision and are at higher risk for periprosthetic fracture after revision. In this paper, we review ... | 25,231,573 | [
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[Exanthems and fever in travellers returning from the tropics]. | Dengue fever with its subtle rash is today more common than malaria in travellers returning to Europe from the tropics (meta-analysis Geo Sentinel network). Up to 5 % of all safari tourists experience African tick bite fever during or soon after their journey; it is caused by rickettsiae and clinically presents with ex... | 25,231,591 | [
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Detection of biomarkers of pathogenic Naegleria fowleri through mass spectrometry and proteomics. | Emerging methods based on mass spectrometry (MS) can be used in the rapid identification of microorganisms. Thus far, these practical and rapidly evolving methods have mainly been applied to characterize prokaryotes. We applied matrix-assisted laser-desorption-ionization-time-of-flight mass spectrometry MALDI-TOF MS in... | 25,231,600 | [
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One-pot synthesis of high molecular weight synthetic heteroprotein dimers driven by charge complementarity electrostatic interactions. | Despite the importance of protein dimers and dimerization in biology, the formation of protein dimers through synthetic covalent chemistry has not found widespread use. In the case of maleimide-cysteine-based dimerization of proteins, we show here that when the proteins have the same charge, dimerization appears to be ... | 25,231,623 | [
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Jack of all trades: versatile catechol crosslinking mechanisms. | Catechols play an important role in many natural systems. They are known to readily interact with both organic (e.g., amino acids) and inorganic (e.g., metal ions, metal oxides) compounds, thereby providing a powerful system for protein curing. Catechol crosslinked protein networks, such as sclerotized cuticle and byss... | 25,231,624 | [
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Monoclonal antibodies against all known variants of EspA: development of a simple diagnostic test for enteropathogenic Escherichia coli based on a key virulence factor. | Enteropathogenic Escherichia coli (EPEC) are a major cause of infant diarrhoea in developing countries and a significant public health issue in industrialized countries. Currently there are no simple tests available for the diagnosis of EPEC. Serology of O-antigens is widely used routinely in many laboratories througho... | 25,231,626 | [
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Oxidant-antioxidant status in the blood of horses with symptomatic recurrent airway obstruction (RAO). | Systemic oxidative stress in horses with recurrent airway obstruction (RAO) is poorly characterized. The goal of this study was to investigate whether equine RAO is associated with systemic disturbances in the oxidant-antioxidant equilibrium. Seven healthy horses and 7 horses with symptomatic RAO. A prospective study. ... | 25,231,643 | [
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"Fighting an uphill battle": experience with the HCV triple therapy: a qualitative thematic analysis. | Hepatitis C virus (HCV) infections are a severe burden on public health worldwide, causing mortality rates triple that of the general population. Since 2011, for both therapy-naive and therapy-experienced genotype 1 patients, the first generation of direct acting antivirals (DAAs), i.e., the protease-inhibitors (PI) te... | 25,231,646 | [
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Personal identity as a form of freedom. | A commentary on "The Ethics of Anonymous Gamete Donation: Is There a Right to Know One's Genetic Origins?" by Inmaculada de Melo-Martín, in the March-April 2014 issue. | 25,231,651 | [
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Circulating progranulin level is associated with visceral fat and elevated liver enzymes: significance of serum progranulin as a useful marker for liver dysfunction. | Progranulin (PRGN) was recently identified as one of the adipokines involved in the development of insulin resistance. Thus, the aim of this study was to explore the importance of PRGN as a novel marker for metabolic diseases in Japanese. A total of 138 subjects were recruited by the Aijinkai Total Health Care Center. ... | 25,231,693 | [
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The pumping lid: investigating multi-material 3D printing for equipment-free, programmable generation of positive and negative pressures for microfluidic applications. | Equipment-free pumping is a challenging problem and an active area of research in microfluidics, with applications for both laboratory and limited-resource settings. This paper describes the pumping lid method, a strategy to achieve equipment-free pumping by controlled generation of pressure. Pressure was generated usi... | 25,231,706 | [
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Assessment of the prophylactic role of aspirin and/or clopidogrel on experimentally induced acute myocardial infarction in hypercholesterolemic rats. | Hyperlipidemia is a risk factor for cardiovascular diseases such as acute infarction. Inflammation and platelet activation are critical phenomena in acute myocardial infarction (AMI). The aim of the study was to assess potential protective effects of aspirin and/or clopidogrel on AMI in hypercholesterolemic rats. Forty... | 25,231,707 | [
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The complete mitochondrial genome of Lota lota (Gadiformes: Gadidae). | In this study, the complete mitochondrial genome (mitogenome) sequence of Lota lota has been determined by long polymerase chain reaction and primer walking methods. The mitogenome is a circular molecule of 16,547 bp in length and contains 37 mitochondrial genes including 13 protein-coding genes, 2 ribosomal RNA (rRNA)... | 25,231,712 | [
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Complete mitochondrial genome of the Freshwater Whipray Himantura dalyensis. | The complete mitochondrial genome of the Freshwater Whipray Himantura dalyensis is presented in this study. It is 17,693 bp in length and contains 37 genes in typical gene order and transcriptional orientation observed in vertebrates. There were a total of 86 bp short intergenic spacers and 22 bp overlaps in the genome... | 25,231,718 | [
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Morphology and Molecular Phylogeny of Pseudocyrtohymena koreana n. g., n. sp. and Antarctic Neokeronopsis asiatica Foissner et al., 2010 (Ciliophora, Sporadotrichida), with a Brief Discussion of the Cyrtohymena Undulating Membranes Pattern. | We discovered a new brackish water oxytrichid Pseudocyrtohymena koreana n. g., n. sp. in South Korea and investigated the new species on the basis of morphology, ontogenesis, and 18S rRNA gene sequences. The new genus has the 18 frontal-ventral-transverse cirri of typical oxytrichids with flexible body, cortical granul... | 25,231,725 | [
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0.03758891,
0.4161676,
-0.2243222,
0.2009439,
-0.1988963,
-0.2189034,
-0.410177,
0.3432521,
-0.2404549,
0.04201838,
-0.1250502,
-0.01404336,
0.2101397,
-0.2963201,
-0.06023025,
-0.4443344,
0.08461697,
-0.07318723,
-0.3159288,
0.2532486,
0.096393,
-0.1510093,
... |
A comparative ICF-CY-based analysis and cultural piloting of the assessment of preschool children's participation (APCP). | The aim of this study was to assess and compare the content and measurement construct of a new measure, the Assessment of Preschool Children's Participation (APCP), with other participation measures that have previously been linked to the ICF-CY, and pilot the APCP item relevance in a Norwegian context. All meaningful ... | 25,231,756 | [
-0.09619533,
0.1977227,
0.05141547,
-0.08358587,
-0.05581271,
-0.2901228,
-0.137523,
0.02763191,
-0.02930312,
-0.1206871,
-0.2171087,
0.005964036,
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-0.08310755,
0.2860363,
-0.4934694,
0.2944047,
0.2389201,
0.2132979,
0.173552... |
Impact of inflammatory bowel disease on disability. | Inflammatory bowel disease can impact individuals at a young age, thus compromising their work productivity. Besides the inability to engage in gainful work, the concept of disability also relates to the patients' diminished ability to undertake household and social activities. A literature search was performed of rece... | 25,231,757 | [
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0.06994358,
0.07589959,
0.1301671,
0.07796225,
-0.1947603,
0.4218557,
0.1289402,
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0.1329965,
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-0.2032355,
0.2177223,
-0.233019,
0.1602037,
-0.1973131,
0.4464948,
-0.02707773,
-... |
Preserving residual renal function in dialysis: what we know. | Residual renal function confers a survival benefit among dialysis patients thought to be related to greater volume removal and solute clearance. Whether the presence of residual renal function is protective or merely a marker for better health is not clear. The basic mechanisms governing the decline or persistence of r... | 25,231,758 | [
0.01019916,
0.03838525,
-0.02754382,
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0.2508758,
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0.03260901,
0.1577345,
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0.108068,
0.07564066,
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0.400218,
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0.01038744,
0.1547403,
0.01243473,
0.03673493,
-0.2972634,
0.1377229,
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... |
Hormone treatment of children and adolescents with gender dysphoria: an ethical analysis. | In the context of transgender health, most people are not comfortable with allowing a twelve-year-old child with gender dysphoria to elect to undergo gender reassignment surgery. The likelihood is too high that the child would be unable to fully comprehend the scope of a decision that carries significant, permanent con... | 25,231,782 | [
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0.06573541,
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0.3115053,
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-0.1256345,
0.3323924,
-0.06861067,
0.04076605,
0.2696351,
0.2822235,
-0.4237567,... |
Ensuring Appropriate Care for LGBT Veterans in the Veterans Health Administration. | Within health care systems, negative perceptions of lesbian, gay, bisexual, and transgender persons have often translated into denial of services, denial of visitation rights to same-sex partners, reluctance on the part of LGBT patients to share personal information, and failure of workers to assess and recognize the u... | 25,231,789 | [
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0.1480727,
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0.1252402,
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0.3167149,
0.04030043,
0.01436038,
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0.08169549,
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-0.5542305,
0.04787355,
0.06047238,
-0.4019926,
-0.04457576,
0.3521818,
-0.2... |
Harmonic demodulation and minimum enhancement factors in field-enhanced near-field optical microscopy. | Field-enhanced scanning optical microscopy relies on the design and fabrication of plasmonic probes which had to provide optical and chemical contrast at the nanoscale. In order to do so, the scattering containing the near-field information recorded in a field-enhanced scanning optical microscopy experiment, has to sur... | 25,231,792 | [
-0.3454555,
0.008562418,
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0.1609743,
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0.02297811,
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-0.5706741,
0.1091271,
0.05291937,
0.0690957,
0.3740736,
0.2429558,
-0.04033681,... |
Symmetry restoration and quantumness reestablishment. | A realistic quantum many-body system, characterized by a generic microscopic Hamiltonian, is accessible only through approximation methods. The mean field theories, as the simplest practices of approximation methods, commonly serve as a powerful tool, but unfortunately often violate the symmetry of the Hamiltonian. The... | 25,231,796 | [
-0.1031732,
0.2381219,
-0.1609713,
0.02820209,
-0.05038225,
-0.2046145,
-0.3452871,
-0.1270077,
0.2537454,
-0.0002055606,
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-0.1559538,
-0.07532453,
0.4449485,
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-0.1802876,
-0.3018802,
-0.1858826,
-0.005330091,
-0.05048694,
-0.0194054,
-0.05395613,
-... |
[Mediating effect of self-efficacy in the relationship between anger and functional health of homeless men]. | The purpose of this study was to examine the mediation of self-efficacy in the relationship between anger and the functional health of homeless men in order to provide a basis for planning nursing interventions to improve the functional health of homeless persons. The participants were 137 homeless men who lived in hom... | 25,231,801 | [
-0.07687819,
0.3312919,
-0.2033052,
0.04797957,
0.3930772,
-0.1783586,
0.05382343,
-0.2770852,
0.01155907,
-0.4221896,
0.1295107,
-0.2402278,
-0.05977841,
-0.1539333,
-0.6794001,
-0.5305789,
-0.006037206,
-0.130313,
0.2599319,
-0.05410153,
-0.07495527,
0.2145743,
-0.10349... |
[Factors affecting dementia prevalence in people aged 60 or over: a community based cross-sectional study]. | This study was done to examine the association between body mass index (BMI) and any type of clinical dementia. Participants were 60,321 people over 60 years of age enrolled in the Seoul Dementia Management Project in 2011. K-MMSE was used to classify participants as having a cognitive impairment and the Clinical Demen... | 25,231,804 | [
0.1337553,
0.3026759,
0.1211893,
-0.001547561,
0.2031584,
-0.3104366,
-0.1445071,
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-0.1601158,
-0.02782991,
0.2833211,
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0.3198099,
-0.2600241,
0.4721596,
0.2452281,
-0.2305076,
-0.4041024,
-0.04477054,
-0.1829809... |
[Association between efficiency and quality of health care in South Korea long-term care hospitals: using the data envelopment analysis and matrix analysis]. | Objectives of this study were to investigate the association between efficiency and quality of health care in Long-term Care Hospitals (LTCH) and determine related factors that would enable achievement of both high efficiency and high quality at the same time. Major data sources were the "2012 Korean Assessment of Prop... | 25,231,807 | [
-0.003962462,
-0.05299485,
0.4431444,
0.1879254,
0.2384956,
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0.5499813,
-0.2368521,
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-0.03520455,
-0.2724413,
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0.2656365,
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0.02601321,
0.2962393,
0.2414165,
-0.09377082,
-0.3048704,
0.1789764,
0.3427376,
0.1666522,
... |
[Effects of newborn care education for first-time fathers on their knowledge and confidence in newborn care at postpartum one month]. | This study was conducted to identify the effects of newborn care education for fathers on their knowledge and confidence in newborn care at postpartum one month. A nonequivalent control group pretest posttest design was used. The participants were 53 first-time fathers of newborns, 27 in experimental group, and 26 in c... | 25,231,808 | [
-0.2098364,
0.07535847,
-0.2863727,
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0.5682819,
0.08949149,
0.2206791,
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0.02842364,
0.1019746,
0.1852933,
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0.3171733,
-0.07850998,
-0.448344,
0.418713,
0.1025947,
0.05830562,
0... |
Hill-sachs lesions in shoulders with traumatic anterior instability: evaluation using computed tomography with 3-dimensional reconstruction. | In patients with traumatic anterior shoulder instability, a large Hill-Sachs lesion is a risk factor for postoperative recurrence. However, there is no consensus regarding the occurrence and enlargement of Hill-Sachs lesions. To investigate the influence of the number of dislocations and subluxations on the prevalence ... | 25,231,817 | [
-0.1881776,
0.1658375,
0.2130081,
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0.0147174,
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0.06941721,
0.3595589,
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0.2323788,
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0.06147559,
0.04153111,
-0.1455383,
0.196862,
0.1362165,
0.2303578,
0.223981,
0.2642553,
-0.1677821,
-0.10... |
Assessment of a Stool Symptom Screener and Understanding the Opioid-Induced Constipation Symptom Experience. | Many patients with chronic opioid-induced constipation (OIC) seek treatment to relieve their symptoms. A symptom screener may be useful in identifying symptomatic OIC patients. The aims of this study were to assess patient understanding of Stool Symptom Screener content and to evaluate how patients described their cons... | 25,231,829 | [
-0.01227374,
0.03305632,
0.03080342,
0.1065755,
-0.08625336,
-0.0009927285,
-0.200304,
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0.3242138,
-0.6227006,
0.0679512,
0.1005593,
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0.2099179,
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0.1393488,
-0.3603424,
0.4356455,
0.1437238,
0.02537015,
-0.2906557,
0.02666819,
-0.1689773,
... |
Metabolic phenotypes of obesity influence triglyceride and inflammation homoeostasis. | We examined the degree of postprandial triglyceride (TG) response over the day, representing a highly dynamic state, with continuous metabolic adaptations, among normal-weight, overweight and obese patients, according to their metabolically healthy or abnormal status. A total of 1002 patients from the CORDIOPREV clinic... | 25,231,836 | [
0.3730806,
0.07924622,
-0.1785383,
-0.3163342,
0.2090839,
-0.4915222,
0.04153262,
0.4757402,
0.1673154,
0.1045326,
0.0560853,
-0.04961286,
-0.01590038,
0.200747,
-0.3625896,
-0.2946882,
-0.2774779,
-0.05330249,
-0.06381789,
0.2438448,
-0.2570567,
0.3061041,
-0.1713466,
... |
Systemic inflammation induces a profound long term brain cell injury in rats. | The long term impact of neuroflammation induced by systemic inflammation on astroglial transcription factor nuclear factor (NF)-kappaB activation in the sub-region of hippocampus as well as its' association with the ultra-structural changes in brain cells are yet unknow. In this study, rats received 10 mg/kg of lipopol... | 25,231,849 | [
0.2063674,
-0.1223115,
-0.0339692,
0.08883612,
0.03659958,
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0.0720497,
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0.09058299,
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0.3533516,
-0.1241169,
0.1219442,
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0.4771265,
0.139792,
... |
Attempted suicide in patients with eating disorders. | Suicide is a major cause of mortality for patients with eating disorders (ED), especially for patients with anorexia nervosa. Attempted suicide is also relatively common in patients with anorexia or bulimia nervosa. This study aimed at examining associations between attempted suicide and trait- and state-dependent char... | 25,231,853 | [
0.03110209,
0.1943736,
0.02016464,
-0.2394054,
0.6919481,
-0.4741608,
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0.1905958,
0.1241676,
0.2535157,
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0.03438276,
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-0.6460696,
0.392419,
-0.04542538,
-0.04785349,
0.1080934,
0.1673612,
-0.1587739,
... |
The relation between diabetes self-efficacy and psychological distress among older adults: do racial and ethnic differences exist? | This study examined racial/ethnic differences in the relationship between diabetes self-efficacy and psychological distress among older adults with diabetes mellitus. Adults aged 60 or older with a diagnosis of diabetes mellitus (N = 3,067) were drawn from the 2009 California Health Interview Survey (CHIS). Hierarchica... | 25,231,883 | [
0.01876408,
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0.04040018,
0.2110474,
0.2355456,
-0.2358065,
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0.1308504,
-0.0755133... |
Expanded umbilical cord blood T cells used as donor lymphocyte infusions after umbilical cord blood transplantation. | Umbilical cord blood (UCB) is an alternative graft source for hematopoietic stem cell transplantation and has been shown to give results comparable to transplantation with other stem cell sources. Donor lymphocyte infusion (DLI) is an effective treatment for relapsed malignancies after hematopoietic stem cell transplan... | 25,231,890 | [
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0.4585454,
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0.1355179,
-0.1726962,
0.1011333,
0.5794739,
0.2765259,
0.1385812,
-... |
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