title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The Confidential Enquiry into Maternal Deaths in South Africa: a case study. | The Confidential Enquiry into Maternal Deaths (CEMD) in South Africa has been operational for 15 years. This case study describes the process of notification and independent assessment of maternal deaths, predominantly in facilities. In the earlier years of the Enquiry, institutional maternal mortality ratio increased ... | 25,236,634 | [
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Maternal near-miss case reviews: the UK approach. | The UK has a well-established programme of Confidential Enquiries into Maternal Deaths and a national system for research into near-miss maternal morbidities, the UK Obstetric Surveillance System. The addition of a programme of near-miss case reviews, the Confidential Enquiries into Maternal Morbidity, permits a comple... | 25,236,644 | [
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Norms, athletic identity, and concussion symptom under-reporting among male collegiate ice hockey players: a prospective cohort study. | Many athletes fail to report concussion symptoms to coaches or medical personnel, putting them at risk for potentially catastrophic neurologic consequences if additional brain trauma is sustained prior to full recovery. The purpose of this study was to determine whether concussion reporting norms prior to the start of ... | 25,236,670 | [
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ROTAS: a rotamer-dependent, atomic statistical potential for assessment and prediction of protein structures. | Multibody potentials accounting for cooperative effects of molecular interactions have shown better accuracy than typical pairwise potentials. The main challenge in the development of such potentials is to find relevant structural features that characterize the tightly folded proteins. Also, the side-chains of residues... | 25,236,673 | [
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Fine tuning the ionic liquid-vacuum outer atomic surface using ion mixtures. | Ionic liquid-vacuum outer atomic surfaces can be created that are remarkably different from the bulk composition. In this communication we demonstrate, using low-energy ion scattering (LEIS), that for ionic liquid mixtures the outer atomic surface shows significantly more atoms from anions with weaker cation-anion inte... | 25,236,677 | [
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Effect of tibial tunnel diameter on femoral tunnel placement in transtibial single bundle ACL reconstruction. | The purpose of this study was to identify the impact of tibial reamer size and placement on the position of femoral tunnel placement via a transtibial approach for anterior cruciate ligament (ACL) reconstruction. Eight cadaveric knee specimens were fixed to a stationary table at 90° of flexion and neutral rotation. Aft... | 25,236,681 | [
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Direct observation of respiratory treatments in cystic fibrosis: parent-child interactions relate to medical regimen adherence. | Use a standardized system to code parent-child interactions during respiratory treatments for cystic fibrosis (CF) and analyze relations between behaviors during treatments and medical regimen adherence. A total of 15 families (53% girls; M age = 8.9 years; SD = 1.8) had three respiratory treatments recorded in the hom... | 25,236,709 | [
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Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans. | Binge drinking, a common pattern of alcohol ingestion, is known to potentiate liver injury caused by chronic alcohol abuse. This study was aimed at investigating the effects of acute binge alcohol on hypoxia-inducible factor-1α (HIF-1α)-mediated liver injury and the roles of alcohol-metabolizing enzymes in alcohol-indu... | 25,236,742 | [
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Strengthening public health pesticide management in countries endemic with malaria or other major vector-borne diseases: an evaluation of three strategies. | Public health pesticides has been the mainstay control of vectors of malaria and other diseases, and public health pests, but there is increasing concern over how these pesticides are being managed. Poor pesticide management could lead to risks to human health and the environment, or diminish the effectiveness of inter... | 25,236,760 | [
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Beef quality traits of heifer in comparison with steer, bull and cow at various feeding environments. | The present review has been focused largely on the sex type differences in beef quality among heifers, cows, steers and bulls in various feeding environments. Genetic groups, feeding systems and gender are the major factors that change carcass characteristics and fatty acid profiles of cattle. Studies identified that h... | 25,236,779 | [
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Enhanced expression of the codon-optimized exo-inulinase gene from the yeast Meyerozyma guilliermondii in Saccharomyces sp. W0 and bioethanol production from inulin. | In the present study, after the exo-inulinase gene INU1 from Meyerozyma guilliermondii was optimized according to the codon usage bias of Saccharomyces cerevisiae, both the optimized gene INU1Y and the native gene INU1 were ligated into the homologous integration expression vector pMIRSC11 and expressed in Saccharomyce... | 25,236,803 | [
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Prevalence of sinus membrane thickening and association with unhealthy teeth: a retrospective review of 831 consecutive patients with 1,662 cone-beam scans. | The purposes of this retrospective review of cone-beam computed tomographic (CBCT) scans were to 1) determine the prevalence of sinus membrane thickening in a consecutive series of patients; 2) identify the prevalence of healthy or unhealthy teeth associated with sinus membrane thickening; and 3) document changes of th... | 25,236,817 | [
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Public Reporting and Demand Rationing: Evidence from the Nursing Home Industry. | This paper examines an under-explored unintended consequence of public reporting: the potential for demand rationing. Public reporting, although intended to increase consumer access to high-quality products, may have provided the perverse incentive for high-quality providers facing fixed capacity and administrative pri... | 25,236,842 | [
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Cytochrome P450 system proteins reside in different regions of the endoplasmic reticulum. | Cytochrome P450 (P450) function is dependent on the ability of these enzymes to successfully interact with their redox partners, NADPH-cytochrome P450 reductase (CPR) and cytochrome b5, in the endoplasmic reticulum (ER). Because the ER is heterogeneous in lipid composition, membrane microdomains with different characte... | 25,236,845 | [
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Effects of Cd injection on osmoregulation and stress indicators in freshwater Nile tilapia. | Freshwater tilapia (Oreochromis niloticus) were intraperitoneally injected with sublethal doses of cadmium (1.25 or 2.5 mg Cd kg(-1) body mass) and sampled after 1, 4 and 7 days in order to evaluate the mechanisms of Cd toxicity at physiological and biochemical levels. Cd levels were significantly elevated in the gill ... | 25,236,868 | [
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Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke. | Brain injury during stroke results in oxidative stress and the release of factors that include extracellular Ca(2+), hydrogen peroxide, adenosine diphosphate ribose, and nicotinic acid adenine dinucleotide phosphate. These alterations of the extracellular milieu change the activity of transient receptor potential melas... | 25,236,871 | [
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Efficacy and safety of linagliptin in subjects with long-standing type 2 diabetes mellitus (>10 years): evidence from pooled data of randomized, double-blind, placebo-controlled, phase III trials. | Long duration of type 2 diabetes mellitus (T2DM) is associated with progressive β-cell loss and may pose a challenge to maintenance of good glycemic control. This study aimed to assess the efficacy and safety of the dipeptidyl peptidase-4 inhibitor linagliptin in an understudied population of patients with long-standin... | 25,236,917 | [
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Molecular assessment of predation by hoverflies (Diptera: Syrphidae) in Mediterranean lettuce crops. | Hoverflies (Diptera: Syrphidae) are generalist predators of a great variety of pests. Nasonovia ribisnigri (Hemiptera: Aphididae) and Frankliniella occidentalis (Thysanoptera: Thripidae) are two common pests in Mediterranean lettuce crops, where they occur alongside alternative prey (e.g., Collembola). A semi-field exp... | 25,236,922 | [
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Max D. Cooper and the delineation of two lymphoid lineages in the adaptive immune system. | This article outlines the fundamental contribution of Max D. Cooper to the analysis of the role of the thymus and of the bursa of Fabricius in the development of immunologic competence both before and after birth, placing a new scientific paradigm in the definition of the ontogeny of the lymphoid tissues. | 25,236,938 | [
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The adaptor protein SAP regulates type II NKT-cell development, cytokine production, and cytotoxicity against lymphoma. | CD1d-restricted NKT cells represent a unique lineage of immunoregulatory T cells that are divided into two groups, type I and type II, based on their TCR usage. Because there are no specific tools to identify type II NKT cells, little is known about their developmental requirements and functional regulation. In our pre... | 25,236,978 | [
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A novel parainfluenza virus type 3 (PIV3) identified from goat herds with respiratory diseases in eastern China. | Parainfluenza virus type 3 (PIV3) is one of the most important viral respiratory pathogens for humans and for many animals, but goat infection has been rarely reported. Starting in Aug 2013, goats in the Jiangsu and Anhui provinces of eastern China suffered severe respiratory diseases. In order to identify the causativ... | 25,236,986 | [
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Dynamic medication adherence modeling in primary prevention of cardiovascular disease: a Markov microsimulation methods application. | Real-world patients' medication adherence is lower than that of clinical trial patients. Hence, the effectiveness of medications in routine practice may differ. The study objective was to compare the outcomes of an adherence-naive versus a dynamic adherence modeling framework using the case of statins for the primary p... | 25,236,996 | [
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Endometrial apical glycoproteomic analysis reveals roles for cadherin 6, desmoglein-2 and plexin b2 in epithelial integrity. | Implantation failure is one of the major causes of infertility and remains a major barrier to assisted reproduction success. Initial receptivity to implantation is regulated by the endometrial luminal epithelium under maternal hormonal control. Identification of epithelial cell surface components involved in embryo att... | 25,237,006 | [
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Primordial germ cell development in the marmoset monkey as revealed by pluripotency factor expression: suggestion of a novel model of embryonic germ cell translocation. | Primordial germ cells (PGCs) are the embryonic progenitors of sperm and egg cells. Mammalian PGCs are thought to actively migrate from the yolk sac endoderm over long distances across the embryo to reach the somatic genital ridges. The general principles of mammalian PGC development were discovered in mice. In contrast... | 25,237,007 | [
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Complete coding sequences of three members of the kokobera group of flaviviruses. | The Kokobera group of flaviviruses circulates in Australia and Papua, New Guinea, and has been associated with occasional human polyarticular disease. To facilitate future studies to identify virulence determinants, the complete coding regions of the Stratford virus, and isolates of the Bainyik virus and Torres virus w... | 25,237,018 | [
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Draft Genome Assembly of Bordetella bronchiseptica ATCC 10580, a Historical Canine Clinical Isolate. | We present the scaffolded genome of Bordetella bronchiseptica ATCC 10580, assembled into 98 contigs. This 5.1-Mb assembly (68.2% G+C content) contains 4,870 coding regions. The strain was originally isolated from canine lung tissue and is used in quality control testing. | 25,237,025 | [
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Inferences from genetically modified mouse models on the skeletal actions of vitamin D. | Vitamin D has pleiotropic extra-skeletal effects which have been noted in mouse models of deletion of either the 25-hydroxy vitamin D 1α-hydroxylase enzyme, cyp27b1 (1OHase(-/-) mice) or of the vitamin D receptor (Vdr(-/-) mice); these may be preventable or reversible by either restoring normal signaling of the 1,25(OH... | 25,237,033 | [
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The early stage of the atrial electroanatomic remodeling as substrates for atrial fibrillation in hypertensive patients. | Hypertension is one of the most important risk factors for atrial fibrillation (AF). Recent studies suggest right atrial remodeling in hypertensive patients may be associated with increased inducibility of AF. This study sought to characterize the electroanatomic features of left and right atria and pulmonary veins (PV... | 25,237,045 | [
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Novel role of kallistatin in vascular repair by promoting mobility, viability, and function of endothelial progenitor cells. | Kallistatin exerts pleiotropic activities in inhibiting inflammation, apoptosis, and oxidative stress in endothelial cells. Because endothelial progenitor cells (EPCs) play a significant role in vascular repair, we investigated whether kallistatin contributes to vascular regeneration by enhancing EPC migration and func... | 25,237,049 | [
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Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli. | Escherichia coli endoribonuclease E has a major influence on gene expression. It is essential for the maturation of ribosomal and transfer RNA as well as the rapid degradation of messenger RNA. The latter ensures that translation closely follows programming at the level of transcription. Recently, one of the hallmarks ... | 25,237,058 | [
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Endovascular treatment of acute intracranial vertebral artery dissection: long-term follow-up results of internal trapping and reconstructive treatment using coils and stents. | Endovascular internal trapping is an effective procedure for the treatment of acute vertebral artery dissection (VAD). However, the outcomes of reconstructive treatment have not been well established. The aim of our study is to evaluate the long-term clinical and angiographic results of endovascular internal trapping o... | 25,237,069 | [
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Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients. | Telomeric G-tails play a pivotal role in maintaining the intramolecular loop structure of telomeres. Previous in vitro studies have suggested that the erosion of telomeric G-tails triggers cellular senescence, leading to organ dysfunction and atherosclerosis. The authors recently established a method to measure telomer... | 25,237,070 | [
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Organic electronics. Room-temperature coupling between electrical current and nuclear spins in OLEDs. | The effects of external magnetic fields on the electrical conductivity of organic semiconductors have been attributed to hyperfine coupling of the spins of the charge carriers and hydrogen nuclei. We studied this coupling directly by implementation of pulsed electrically detected nuclear magnetic resonance spectroscopy... | 25,237,097 | [
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The genetic architecture of maize (Zea mays L.) kernel weight determination. | Individual kernel weight is an important trait for maize yield determination. We have identified genomic regions controlling this trait by using the B73xMo17 population; however, the effect of genetic background on control of this complex trait and its physiological components is not yet known. The objective of this st... | 25,237,113 | [
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Adolescent marijuana users have elevated risk-taking on the balloon analog risk task. | Adolescents who engage in regular marijuana use may have a higher propensity to take unsafe risks despite the possible negative consequences. We compared adolescents with a history of regular marijuana use to non-using teens on a behavioral measure of risk-taking. Given the involvement of the pre-frontal cortex in both... | 25,237,125 | [
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Arabidopsis myosin XI: a motor rules the tracks. | Plant cell expansion relies on intracellular trafficking of vesicles and macromolecules, which requires myosin motors and a dynamic actin network. Arabidopsis (Arabidopsis thaliana) myosin XI powers the motility of diverse cellular organelles, including endoplasmic reticulum, Golgi, endomembrane vesicles, peroxisomes, ... | 25,237,128 | [
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Rewards and challenges of providing HIV testing and counselling services: health worker perspectives from Burkina Faso, Kenya and Uganda. | The rapid scale-up of human immunodeficiency virus (HIV) testing, counselling and treatment throughout sub-Saharan Africa has raised questions about how to protect patients' rights to consent, confidentiality, counselling and care in resource-constrained settings. The Multi-country African Testing and Counselling for H... | 25,237,134 | [
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Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane division. | Drp1 is a dynamin-like GTPase that mediates mitochondrial and peroxisomal division in a process dependent on self-assembly and coupled to GTP hydrolysis. Despite the link between Drp1 malfunction and human disease, the molecular details of its membrane activity remain poorly understood. Here we reconstituted and direct... | 25,237,193 | [
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Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100. | Most genetic defects that arrest B-cell development in the bone marrow present early in life with agammaglobulinemia, whereas incomplete antibody deficiency is usually associated with circulating B cells. We report 3 related individuals with a novel form of severe B-cell deficiency associated with partial persistence o... | 25,237,204 | [
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Guidelines for the Investigation of Mediating Variables in Business Research. | Business theories often specify the mediating mechanisms by which a predictor variable affects an outcome variable. In the last 30 years, investigations of mediating processes have become more widespread with corresponding developments in statistical methods to conduct these tests. The purpose of this article is to pro... | 25,237,213 | [
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Comparison of the in vitro Effects of One-day Exposure to Amodiaquine and Praziquantel on Schistosoma mansoni Adult Worm Pairs. | It has been demonstrated that continuous exposure to amodiaquine (AQ) alone elicits in vitro antischistosomal activities at concentrations of 1-10 μg/ml. However, orally administered drugs reach a peak blood concentration within one or two hours and then gradually decrease. The blood concentration does not remain at a ... | 25,237,285 | [
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Knowledge-based identification of sleep stages based on two forehead electroencephalogram channels. | Sleep quality is important, especially given the considerable number of sleep-related pathologies. The distribution of sleep stages is a highly effective and objective way of quantifying sleep quality. As a standard multi-channel recording used in the study of sleep, polysomnography (PSG) is a widely used diagnostic sc... | 25,237,291 | [
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Corrigendum: The effect of stimulus context on the buildup to stream segregation. | [This corrects the article on p. 93 in vol. 8, PMID: 24808822.]. | 25,237,292 | [
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Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release. | Nicotinic acetylcholine receptors (nAChRs) potently regulate dopamine (DA) release in the striatum and alter cocaine's ability to reinforce behaviors. Since cocaine is a weak nAChR inhibitor, we hypothesized that cocaine may alter DA release by inhibiting the nAChRs in DA terminals in the striatum and thus contribute t... | 25,237,305 | [
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Predictors of acute kidney injury in geriatric patients undergoing total knee replacement surgery. | Few studies have focused on patients' characteristics that affects acute kidney injury (AKI) after total knee replacement surgery (TKR). The primary objective of this retrospective study was to identify patients' characteristics associated with AKI after TKR. Between January 2008 and December 2009, 659 patients with a ... | 25,237,322 | [
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A highly sensitive kinetic spectrophotometric method for the determination of ascorbic Acid in pharmaceutical samples. | In this study, a new reaction system for quantitative determination of ascorbic acid was introduced. The developed method is based on inhibitory effect of ascorbic acid on the Orange G-bromate system. The change in absorbance was followed spectrophotometrically at 478 nm. The dependence of sensitivity on the reaction v... | 25,237,333 | [
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Modeling of outpatient prescribing process in iran: a gateway toward electronic prescribing system. | Implementation of electronic prescribing system can overcome many problems of the paper prescribing system, and provide numerous opportunities of more effective and advantageous prescribing. Successful implementation of such a system requires complete and deep understanding of work content, human force, and workflow of... | 25,237,369 | [
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Effect of hepatitis B virus genotypes on the efficacy of adefovir dipivoxil antiviral therapy. | Hepatitis B is a common infectious disease in China. Many studies have shown that the genotype of hepatitis B virus (HBV) is probably associated with the efficacy of some antiviral drugs such as interferon α (IFN-α) and Lamivudine (LAM). However, the association between HBV genotype and adefovir dipivoxil (ADV) is cont... | 25,237,370 | [
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Empyema necessitatis in a patient on peritoneal dialysis. | Empyema necessitatis is a rare complication of an empyema. Although the incidence is thought to be decreased in the post-antibiotic era, immunocompromised patients such as patients with chronic kidney disease on dialysis are still at a higher risk. A 56-year-old woman on peritoneal dialysis presented with an enlarging ... | 25,237,382 | [
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Sequence Diversity Diagram for comparative analysis of multiple sequence alignments. | The sequence logo is a graphical representation of a set of aligned sequences, commonly used to depict conservation of amino acid or nucleotide sequences. Although it effectively communicates the amount of information present at every position, this visual representation falls short when the domain task is to compare b... | 25,237,396 | [
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Prevalence of diabetes mellitus in patients with newly evaluated papillary thyroid cancer. | This study investigates whether diabetes mellitus is a risk factor for the development of papillary thyroid cancer, using an age-, gender-, and race-matched analysis. We retrospectively reviewed the charts of 1559 patients with newly evaluated thyroid cancer over a 4-year period at our institution and identified 1313 p... | 25,237,398 | [
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Defining hospitalist physicians using clinical practice data: a systems-level pilot study of Ontario physicians. | Hospitalists have become dominant providers of inpatient care in many North American hospitals. Despite the global growth of hospital medicine, no objective method has been proposed for defining the hospitalist discipline and delineating among inpatient practices on the basis of physicians' clinical volumes. We propose... | 25,237,402 | [
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Antiallodynic effect of intrathecal epigallocatechin-3-gallate due to suppression of reactive oxygen species. | Green tea modulates neuropathic pain. Reactive oxygen species (ROS) are suggested as a key molecule in the underlying mechanism of neuropathic pain in the spinal cord. We examined the effect of epigallocatechin-3-gallate (EGCG), the major catechin in green tea, in neuropathic pain and clarified the involvement of ROS o... | 25,237,449 | [
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Risk of continuing planned surgery after endovascular repair of subclavian artery injury: a case report. | Endovascular repair with covered stents has been widely used to treat subclavian and axillary artery injuries and has produced promising early results. The possibility of a thromboembolism occurring in cerebral arteries during an endovascular procedure should be a cause for concern. In the case of endovascular manageme... | 25,237,452 | [
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Anesthetic management of transoral natural orifice transluminal endoscopic surgery: two cases report. | Natural orifice transluminal endoscopic surgery (NOTES) is an evolving field of minimally invasive surgery. NOTES reaches the target organ by inserting the endoscope through a natural orifice (e.g. mouth, anus, urethra, vagina) and offers advantages of less postoperative pain and lower complication rate. Since its firs... | 25,237,454 | [
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Hope, optimism and delusion. | Optimism is generally accepted by psychiatrists, psychologists and other caring professionals as a feature of mental health. Interventions typically rely on cognitive-behavioural tools to encourage individuals to 'stop negative thought cycles' and to 'challenge unhelpful thoughts'. However, evidence suggests that most ... | 25,237,497 | [
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The College reply to Francis misses the big question: a commentary on OP92. | The College has recently published an occasional paper in response to the Francis inquiry into the care at Mid Staffordshire NHS Foundation Trust. We consider that it overlooks one key question implicit in the inquiry's recommendations: 'Is the business model of care fit for purpose?' We question whether the business m... | 25,237,535 | [
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The demonisation of psychiatrists in fiction (and why real psychiatrists might want to do something about it). | To encourage psychiatric practitioners to be aware of and to work to counteract the representations of the profession as evil manipulators in fiction, film and popular culture. A wide-ranging number of representative sources portraying psychiatrists are explored. It is demonstrated that psychiatry is overwhelmingly pre... | 25,237,540 | [
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Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphism in Iranian Women With Idiopathic Recurrent Pregnancy Losses. | Recurrent pregnancy loss (RPL) is a serious problem for pregnancy. There is evidence that vascular complications play a principal role in RPL. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Polymorphisms (C677T, A1298C) of MTHFR gene are associated with decreased MTHFR activity. The a... | 25,237,572 | [
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Involvement of synaptic genes in the pathogenesis of autism spectrum disorders: the case of synapsins. | Autism spectrum disorders (ASDs) are heterogeneous neurodevelopmental disorders characterized by deficits in social interaction and social communication, restricted interests, and repetitive behaviors. Many synaptic protein genes are linked to the pathogenesis of ASDs, making them prototypical synaptopathies. An array ... | 25,237,665 | [
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Five-year outcome of a retrospective cohort study on the rehabilitation of completely edentulous atrophic maxillae with immediately loaded zygomatic implants placed extra-maxillary. | To report retrospectively on the 5-year follow-up results of the rehabilitation of complete edentulous atrophied maxillae, using extra-maxillary zygomatic implants alone or in combination with conventional implants. This retrospective report includes an initial cohort of 39 patients (30 women and 9 men), with a mean ag... | 25,237,671 | [
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Orally inhaled drug performance testing for product development, registration, and quality control. | A DPI can be split into three different modules; device, formulation, process. These are developed in parallel, and together with the user they provide the performance of an inhalation product. During product development, these modules are evolving and changing, whereas the requirements on an inhalation product are alw... | 25,237,712 | [
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Progressive neurodegenerative syndrome in a patient with X-linked agammaglobulinemia receiving intravenous immunoglobulin therapy. | A progressive encephalopathy of unknown etiology has been described in patients with primary immunodeficiency disorders. In this report, we characterize the clinical features of this progressive neurodegenerative dementing disorder in a young man with Bruton agammaglobulinemia, through neuropsychological tests and a vi... | 25,237,746 | [
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Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities. | The ubiquitin proteasome system (UPS) plays a role in the regulation of most cellular pathways, and its deregulation has been implicated in a wide range of human pathologies that include cancer, neurodegenerative and immunological disorders and viral infections. Targeting the UPS by small molecular regulators thus prov... | 25,237,759 | [
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Proteomic profiling during the pre-competent to competent transition of the biofouling polychaete Hydroides elegans. | The polychaete, Hydroides elegans, is a tube-building worm that is widely distributed in tropical and subtropical seas. It is a dominant fouling species and thus a major target organism in antifouling research. Here, the first high-throughput proteomic profiling of pre-competent and competent larvae of H. elegans is re... | 25,237,770 | [
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Stainless steel in coastal seawater: sunlight counteracts biologically enhanced cathodic kinetics. | The influence of sunlight of varying intensity on the performance of UNS S30400 stainless steel (SS) was explored under conditions of natural biofilm development in coastal seawater. In a series of tests performed outdoors under an opaque roof, a range of shades were fashioned to impart varied amounts of diurnal light.... | 25,237,771 | [
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Testicular malakoplakia: a rare sonographic mimic of malignancy. | Testicular malakoplakia is a rare, benign condition that most often occurs in an immunocompromised patient with chronic infection. Its occurrence is acute, with pain and testicular enlargement. Sonography is commonly performed to evaluate the patient for epididymitis or torsion. The appearance of testicular malakoplaki... | 25,237,793 | [
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Active liquid crystal tuning of metallic nanoantenna enhanced light emission from colloidal quantum dots. | A system comprising an aluminum nanoantenna array on top of a luminescent colloidal quantum dot waveguide and covered by a thermotropic liquid crystal (LC) is introduced. By heating the LC above its critical temperature, we demonstrate that the concomitant refractive index change modifies the hybrid plasmonic-photonic ... | 25,237,822 | [
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Clinicopathological characteristics and therapeutic outcomes in thyrotropin-secreting pituitary adenomas: a single-center study of 90 cases. | The aim of this study was to analyze clinicopathological characteristics and treatment outcomes in a large single-center clinical series of cases of thyrotropin (TSH)-secreting pituitary adenomas. The authors retrospectively reviewed clinical, pathological, and treatment characteristics of 90 consecutive cases of TSH-s... | 25,237,847 | [
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Human therapies as a successful liaison between chemistry and biology. | The development of novel therapies is arguably one of the most important roles of modern chemistry and biology. Here, we shed light on a particular class of human therapies in which synthetic chemical entities are attached to expressed biologicals (proteins) with the goal to enhance clinical activity. We focus our disc... | 25,237,852 | [
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The University of North Carolina's Health Care Pharmacy Assistance Progam. | UNC Health Care has a Pharmacy Assistance Program (PAP) that provides financial assistance to uninsured patients in North Carolina who need prescription medications. Despite significant investment in the program, little is known about the patients accessing it or the specific health care services they use. Our objectiv... | 25,237,867 | [
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Statistical analysis-based error models for the Microsoft Kinect(TM) depth sensor. | The stochastic error characteristics of the Kinect sensing device are presented for each axis direction. Depth (z) directional error is measured using a flat surface, and horizontal (x) and vertical (y) errors are measured using a novel 3D checkerboard. Results show that the stochastic nature of the Kinect measurement ... | 25,237,896 | [
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TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity. | p53 plays a key role in regulating DNA damage response by suppressing cell cycle progression or inducing apoptosis depending on extent of DNA damage. However, it is not clear why mild genotoxic stress favors growth arrest, whereas excessive lesions signal cells to die. Here we showed that TAp73, a p53 homologue thought... | 25,237,903 | [
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Photoinduced hydrogen evolution by a pentapyridine cobalt complex: elucidating some mechanistic aspects. | A new hydrogen evolving cobalt catalyst 1 based on a pentapyridine ligand has been synthesized and characterized. Its photocatalytic activity in the presence of a Ru(bpy)3(2+) sensitizer and ascorbic acid as a sacrificial electron donor has been screened in purely buffered aqueous solutions showing TONs and TOFs strong... | 25,237,910 | [
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Newly licensed registered nurse job turnover and turnover intent. | Through survey data, this study examines job leaving behaviors of newly licensed registered nurses and identifies educational and managerial issues that need to be addressed to retain them. Within 1.5-2.5 years of graduating, one third of all respondents had left their first job, most for work-related reasons. Predicto... | 25,237,913 | [
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Teaching nurses how to teach: strategies to enhance the quality of patient education. | This article describes the development of a training course for nurses that focused on teach-back as a key strategy for patient education. It describes evaluative methods used to collect feedback and determine effectiveness of education based on nurses' perception and self-assessment of their patient educational skills... | 25,237,917 | [
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Methods to estimate breeding values in honey bees. | Efficient methodologies based on animal models are widely used to estimate breeding values in farm animals. These methods are not applicable in honey bees because of their mode of reproduction. Observations are recorded on colonies, which consist of a single queen and thousands of workers that descended from the queen ... | 25,237,934 | [
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Tale of two diseases: amyotrophic lateral sclerosis and frontotemporal dementia. | Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) were independently described in clinical and pathological details more than a century ago. Recent breakthrough discoveries identifying common genes that are causal to either ALS or FTD or an overlapping ALS-FTD syndrome have dramatically transformed ... | 25,237,937 | [
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Evaluation of 1p and 14q status, MIB-1 labeling index and progesterone receptor immunoexpression in meningiomas: Adjuncts to histopathological grading and predictors of aggressive behavior. | Meningiomas are benign central nervous system tumors; however, significant fraction recurs, irrespective of histological grade. We performed fluorescence in-situ hybridization for 1p36 and 14q32, and immunohistochemistry for progesterone receptor (PR), p53 and MIB-1 on 84 meningiomas. Sixty-four were convexity tumors (... | 25,237,942 | [
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Subarachnoid hemorrhage with blister aneurysms: Endovascular management. | Blister aneurysms of are rare lesions representing a real challenge for diagnosis and management. They typically show small size, hemispherical shape, fragile wall, broad neck, and are arising from non-branching sites of intracranial arteries. We retrospectively reviewed all aneurysms treated at our institution. Sevent... | 25,237,945 | [
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Reduction in Pain and Inflammation Associated With Chronic Low Back Pain With the Use of the Medical Food Theramine. | Management of chronic back pain is a challenge for physicians. Although standard treatments exert a modest effect, they are associated with narcotic addiction and serious side effects from nonsteroidal antiinflammatory agents. Moreover, neurotransmitter depletion from both the pain syndrome and therapy may contribute t... | 25,237,981 | [
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Inhaled drug delivery in the hands of the patient. | Asthma and chronic obstructive pulmonary disease (COPD) are both diseases with an increasing prevalence worldwide. Inhaled therapy for these conditions has a number of advantages over systemic therapy, but requires the patients to use, and to master the use of, an inhaler device. However, many patients cannot use inhal... | 25,238,005 | [
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[In-hospitaltraumamanagement - trauma suite diagnostics]. | Whole-body CT is considered gold standard for diagnosis of the multiple injured patient in the trauma suite. So far, no guidelines exist concerning its indication. The trauma team (Trauma Surgery/Visceral Surgery, Anaesthesiology, Radiology) should use standardized triage-criteria for the indication of whole-body CT. T... | 25,238,013 | [
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-0.2463735,
0.2411047,
-0.01850783,
0.05815461,
0.5104918,
0.004802728,
-0.1054905,
0... |
Upconversion-agent induced improvement of g-C3N4 photocatalyst under visible light. | Herein, we report the use of upconversion agents to modify graphite carbon nitride (g-C3N4) by direct thermal condensation of a mixture of ErCl3·6H2O and the supramolecular precursor cyanuric acid-melamine. We show the enhancement of g-C3N4 photoactivity after Er(3+) doping by monitoring the photodegradation of Rhodami... | 25,238,039 | [
-0.1952238,
0.3169863,
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-0.1321497,
0.1750517,
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0.174669,
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0.1499938,
0.1416233,
0.05837484,
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0.1909468,
0.1192361,
-0.215251,
0.3875342,
0.1855583,
-0.02778249,
0.... |
The correlation of α-globin gene mutations and the XmnI polymorphism with clinical severity of Hb E/β-thalassemia. | Clinical severity assessment and molecular analysis of β-, α-globin genes and the -158 (C > T) XmnI polymorphism of the (G)γ-globin gene were performed in 80 pediatric patients with Hb E (HBB: c.79G > A)/β-thalassemia (β-thal) to investigate the effects of coinheritance of α-thalassemia (α-thal) and other molecul... | 25,238,043 | [
0.156216,
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0.5916137,
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0.2556633,
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0.04593998,
0.1650947,
0.1130493,
0.3426558,
0.3022641,
-0.003023258,... |
Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma. | Liposarcoma is one of the most common histologic types of soft tissue sarcoma and is frequently an aggressive cancer with poor outcome. Hence, alternative approaches other than surgical excision are necessary to improve treatment of well-differentiated/dedifferentiated liposarcoma (WDLPS/DDLPS). For this reason, we per... | 25,238,053 | [
0.1938699,
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0.1276633,
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0.06514394,
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0.07858615,
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0.1919707,
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0.01796057,
0.07502047,
-0.3488221,
... |
(Un)targeted metabolomics in Asteraceae: probing the applicability of essential-oil profiles of senecio L. (Senecioneae) taxa in chemotaxonomy. | The possible applicability of (un)targeted metabolomics (volatile metabolites) for revealing taxonomic/evolutionary relationships among Senecio L. species (Asteraceae; tribe Senecioneae) was explored. Essential-oil compositional data of selected Senecio/Senecioneae/Asteraceae taxa (93 samples in total) were mutually co... | 25,238,075 | [
-0.2074664,
0.1246524,
0.4784491,
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0.003450341,
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0.1431275,
0.1055566,
0.4880986,
0.194696,
0.6110937,
-0.3962787,
0.015... |
The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors. | Adaptation of malignant cells to the hostile milieu present in tumors is an important determinant of their survival and growth. However, the interaction between tumor-linked stress and antitumor immunity remains poorly characterized. Here, we show the critical role of the cellular stress sensor C/EBP-homologous protein... | 25,238,096 | [
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0.1287187,
0.03751909,
0.03206497,
-... |
Ctla-4 modulates the differentiation of inducible Foxp3+ Treg cells but IL-10 mediates their function in experimental autoimmune encephalomyelitis. | In vitro induced Foxp3+ T regulatory (iTreg) cells form a novel and promising target for therapeutic tolerance induction. However, the potential of these cells as a target for the treatment of various immune diseases, as well as the factors involved in their development and function, remain debated. Here, we demonstrat... | 25,238,105 | [
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0.01320794,
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0.3344642,
0.08395308,... |
DNA barcoding of commercially important Grouper species (Perciformes, Serranidae) in the Philippines. | Fish identification is generally challenging because of their unpronounced and overlapping morphological characters which is true in grouper species. In the Philippines, an updated, reliable and accurate inventory of this high value commercial groupers has not been carried out previously. Using molecular tools in the i... | 25,238,110 | [
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0.41488,
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0.3624398,
0.3490326,
0.1112161,
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0.14298,
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... |
Parallel alternating sliding knots are effective for ligation of mesenteric arteries during resection and anastomosis of the equine jejunum. | In literature only one article describes and compares methods of achieving hemostasis in equine mesenteric arteries during jejunal resection and anastomosis, and most textbooks favor ligating-dividing mechanical devices. The latter method cannot always be used, not least because the devices are expensive and in some ca... | 25,238,115 | [
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0.05034354,
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... |
Abdominal circumference or gastric residual volume as measure of feed intolerance in VLBW infants. | The aim of the study was to compare prefeed abdominal circumference (AC) and gastric residual volume (GRV) as a measure of feed intolerance in very-low-birth-weight infants (VLBW). Eighty VLBW infants were randomized to 2 groups; feed intolerance was monitored by measuring either GRV group or prefeed AC group. The prim... | 25,238,118 | [
0.2309237,
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0.02263364,
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0.1135289,
0.01064824,
... |
Bioactive hemicelluloses alkali-extracted from Fallopia sachalinensis leaves. | Fallopia sachalinensis, regarded as an invasive plant in Europe and designated for disposal, is traditionally used in Japan and China as herbal medicine. Attempted for valorization of the leaves, this paper reports on two protein-free polysaccharide fractions, a neutral (FS-5A) and an acidic (FS-5B) one, obtained via a... | 25,238,126 | [
-0.1612702,
0.05386723,
0.1536413,
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0.01326843,
0.5793349,
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... |
Bis(acetylacetonato)bis(pyrazolato)ruthenate(iii) as a redox-active scorpionate ligand. | The potential of a new anionic octahedral metal complex [Ru(III)(acac)2(pz)2](-) ((-)) (pzH = pyrazole) as a ligand with a scorpionate coordination behaviour like tris(pyrazolyl)borate (tp) and reversible redox activity is presented. Trinuclear metal complexes, [Ru(III)2Zn(II)(acac)4(pz)4] () and [Ru(II)Ru(III)2(acac)4... | 25,238,163 | [
0.04761494,
0.2024945,
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0.2344387,
0.1134037,
0.2364054,
-0.1083882,
0.06383052,
-0.1197212... |
Pomegranate seed oil: Effect on 3-nitropropionic acid-induced neurotoxicity in PC12 cells and elucidation of unsaturated fatty acids composition. | Seed oils are used as cosmetics or topical treatment for wounds, allergy, dandruff, and other purposes. Natural antioxidants from plants were recently reported to delay the onset or progress of various neurodegenerative conditions. Over one thousand cultivars of Punica granatum (Punicaceae) are known and some are tradi... | 25,238,165 | [
-0.2077878,
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0.0496707,
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0.05896312,
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0.3969444,
0.3381085,
0.1179796,
0.2604305,
-0.1321961,
-0... |
Adenocarcinoma in situ of the uterine cervix--a systematic review. | This study aimed to review literature if therapeutic strategies in adenocarcinoma in situ of the cervix could lead to a more conservative approach. A review of the literature was conducted using a Medline search for articles published between 1966 and 2013. Thirty-five studies showed that after a radical cone, 16.5% re... | 25,238,167 | [
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0.004076004,
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0.003095578,
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-0.06798244,
0.00134853,
-0.4075471,
0.1829896,
0.06132501,
-0.182060... |
High resolution 3D diffusion cardiovascular magnetic resonance of carotid vessel wall to detect lipid core without contrast media. | Without the need of contrast media, diffusion-weighted imaging (DWI) has shown great promise for accurate detection of lipid-rich necrotic core (LRNC), a well-known feature of vulnerable plaques. However, limited resolution and poor image quality in vivo with conventional single-shot diffusion-weighted echo planar imag... | 25,238,168 | [
-0.1104079,
0.1505002,
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0.01428553,
0.0158304,
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0.3804711,
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0.5161083,
-0.2194147,... |
Gastric cancer following bariatric surgery: a review. | Bariatric procedures can induce a massive weight loss that lasts for >15 years after surgery; in addition, they achieve important metabolic effects including diabetes resolution in the majority of morbidly obese patients. However, some bariatric interventions may cause gastroesophageal reflux disease and other serio... | 25,238,176 | [
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0.1583172,
-0.1843245,
-... |
High performance sulfur, nitrogen and carbon doped mesoporous anatase-brookite TiO₂ photocatalyst for the removal of microcystin-LR under visible light irradiation. | Carbon, nitrogen and sulfur (C, N and S) doped mesoporous anatase-brookite nano-heterojunction titania photocatalysts have been synthesized through a simple sol-gel method in the presence of triblock copolymer Pluronic P123. XRD and Raman spectra revealed the formation of anatase and brookite mixed phases. XPS spectra ... | 25,238,189 | [
-0.1945268,
0.1593032,
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0.2495972,
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0.1087025,
0.4994412,
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0.01871351,
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-0.1257... |
Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission. | Herein we aimed to understand how nanoscale clustering of RGD ligands alters the mechano-regulation of their integrin receptors. We combined molecular tension fluorescence microscopy with block copolymer micelle nanolithography to fabricate substrates with arrays of precisely spaced probes that can generate a 10-fold f... | 25,238,229 | [
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0.05619845,
-0.1497715,
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0.3688256,
0.07817269,
0.1... |
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